Atrial shunt integrated with PH monitoring and used for monitoring and relieving heart failure

Abstract

The invention provides an atrial shunt integrated with PH monitoring and used for monitoring and relieving heart failure, and the atrial shunt is characterized in that the atrial shunt comprises a main structure which is provided with a through-flow hole, and the through-flow hole is used for establishing a blood flow channel of an atrial; the support is arranged at the axial end of the main structure and used for fixing the main structure to a puncture hole of a heart interval. The electromagnetic actuator comprises an opening and closing structure which can be arranged in the through-flow hole in an opening and closing mode and a permanent magnet arranged on the main structure, the opening and closing structure comprises a plurality of movable sharp petals which are annularly arranged at the end opening of the through-flow hole and have the function of a one-way valve, and the permanent magnet is configured to drive the sharp petals to conduct opening and closing actions so as to change the circulation area of the through-flow hole; the composite sensor is arranged on the main structure and is used for detecting the intracardiac pressure in the atrium and the pH value of intracardiac fluid and generating a sensing signal; the control circuit is arranged on the main structure and electrically connected with the composite sensor and the electromagnetic actuator. The control circuit is configured to control opening and closing actions of the electromagnetic actuator according to the received sensing signals.

Description

TECHNICAL FIELD

[0001] Embodiments of the present disclosure belong to the technical field of atrial shunt, and particularly relate to an atrial shunt integrated with PH monitoring for monitoring and relieving heart failure. BACKGROUND

[0002] As an interventional therapy for treating heart failure, atrial shunt creates a shunt passage in the atrial septum to divert left atrial blood to the right atrium, thereby reducing the left atrial pressure load. However, the traditional passive atrial shunt has a significant defect: it is difficult to avoid the reverse shunt from the right atrium to the left atrium under the periodic pressure fluctuations of the heart, resulting in the mixing of arterial blood and venous blood, disrupting the double-circulation physiological circuit of "systemic circulation-pulmonary circulation", not only reducing blood oxygen delivery efficiency, but also increasing the volume load of the right atrium, which may cause or exacerbate right heart failure in the long term.

[0003] In addition, the traditional shunt lacks real-time pressure monitoring and flow regulation functions, and cannot dynamically adapt to the patient's hemodynamic state. If the left atrial pressure needs to be continuously monitored, an independent wireless pressure sensor must be implanted, which not only increases the complexity and cost of the operation, but also cannot form a closed-loop linkage control between the sensor and the shunt.

[0004] Therefore, there is an urgent need for an atrial shunt device integrated with real-time monitoring and active regulation functions to achieve precise, safe, and dynamic heart failure management and to avoid secondary damage caused by blood reflux. In addition, the existing shunt cannot realize real-time monitoring of the local environment such as pH value in the heart, and heart failure patients often have metabolic disorders or acid-base changes caused by local ischemia. The lack of pH parameters limits the comprehensiveness and early warning ability of treatment. SUMMARY

[0005] Embodiments of the present disclosure aim to at least solve one of the technical problems existing in the prior art, and provide an atrial shunt integrated with PH monitoring for monitoring and relieving heart failure.

[0006] In one aspect of embodiments of the present disclosure, an atrial shunt integrated with PH monitoring for monitoring and relieving heart failure is provided, comprising: a main structure provided with a through-flow hole penetrating through its axial direction, the through-flow hole being used to establish a blood flow passage between atria; a stent provided at an axial end of the main structure, the stent being used to fix the main structure at a puncture hole of the heart septum; an electromagnetic actuator comprising an opening and closing structure provided in the through-flow hole in an openable and closable manner, and a permanent magnet provided on the main structure, the opening and closing structure comprising a plurality of movable sharp petals having a one-way valve function and arranged in a ring at a port of the through-flow hole, the permanent magnet being configured to drive the opening and closing action of the sharp petals to change the flow area of the through-flow hole. a composite sensor disposed on the main structure, the composite sensor being configured to detect an intracardiac pressure and a pH value of an intracardiac fluid in an atrium and generate a sensing signal; and a control circuit disposed on the main structure and electrically connected to the composite sensor and the electromagnetic actuator, respectively, the control circuit being configured to control an opening and closing action of the electromagnetic actuator according to the received sensing signal.

[0007] Optionally, the cusp includes a planar inductor, and a flexible membrane disposed on opposite sides of the planar inductor and connected to the main structure.

[0008] Optionally, the peripheral wall of the main structure is provided with a prefabricated groove, and the permanent magnets are in the shape of a circular arc and are provided with two, wherein the two permanent magnets are installed in the prefabricated groove in a magnetically central symmetric manner to form a ring-distributed concentrated magnetic field.

[0009] Optionally, the control circuit includes a rectifier bridge, a voltage stabilizing filter circuit, and a switch control unit connected in sequence; the rectifier bridge and the voltage stabilizing filter circuit are configured to rectify and stabilize the alternating current obtained wirelessly; the switch control unit is electrically connected to the composite sensor and the electromagnetic actuator, respectively, and is configured to control the current direction and on-off of the planar inductor according to the sensing signal.

[0010] Optionally, the composite sensor is a passive and wireless pressure-pH composite sensor.

[0011] Optionally, the composite sensor includes a wire-wound inductor, a pressure-sensitive capacitor, and a pH sensing unit, the wire-wound inductor is disposed on the outer periphery of the main structure, the pressure-sensitive capacitor is disposed on the axial end of the main structure, and the pH sensing unit is disposed on the surface of the control circuit or the surface of a biocompatible packaging layer, and forms an RLC parallel resonance circuit with the wire-wound inductor and the pressure-sensitive capacitor, and the resonance frequency of the RLC parallel resonance circuit is configured to respond to changes in intracardiac pressure, and the bandwidth responds to changes in the pH of the intracardiac fluid.

[0012] Optionally, it further includes a flange structure disposed on the axial end of the main structure, the flange structure being configured to fix the wire-wound inductor to the main structure.

[0013] Optionally, the pressure-sensitive capacitor is a parallel-plate variable capacitor.

[0014] Optionally, the pH sensing unit includes an iridium oxide or polyaniline-based thin film electrode, wherein the resistance value of the thin film electrode responds to changes in the pH value of the intracardiac fluid.

[0015] Optionally, the stent is constrained in the through-flow hole in the delivery state, and the radial dimension of the stent is less than or equal to the diameter of the main structure; in the release state, the stent is deployed in the heart, and the radial dimension of the stent after deployment is greater than the diameter of the main structure and the diameter of the puncture hole.

[0016] The beneficial effects of embodiments of the present disclosure include: The atrial shunt of the present application integrates pH and intracardiac pressure monitoring functions, and the through-flow hole can achieve shunt between the left atrium and the right atrium to reduce the left atrial pressure or the right atrial pressure. The cusp structure has a one-way valve function, which can effectively prevent the left and right atrial regurgitation, avoid excessive mixing of arterial and venous blood, and avoid excessive load on the right atrium. The composite sensor can continuously monitor the intracardiac pressure to provide real-time intracardiac pressure data support. The electromagnetic actuator can dynamically adjust the opening degree of the through-flow hole according to the sensing signal of the composite sensor, and realize precise and active control of the shunt effect.

[0017] Compared with the traditional passive shunt, the present application can significantly reduce the risk of regurgitation and left / right heart complications while ensuring effective shunt and pressure reduction, and improve the closed-loop management ability and long-term safety of heart failure treatment. In addition, the pH sensing unit is integrated in the composite sensor to form an RLC parallel resonance system, which can realize passive and wireless synchronous monitoring of the intracardiac liquid pH value, provide early warning for complications such as heart failure combined with metabolic acidosis, and enhance the comprehensiveness and forward-looking of treatment. BRIEF DESCRIPTION OF DRAWINGS

[0018] Figure 1 is a structural schematic diagram of an atrial shunt for monitoring and relieving heart failure provided by an embodiment of the present application, which integrates PH monitoring; Figure 2 is a partial structural schematic diagram of an atrial shunt for monitoring and relieving heart failure provided by an embodiment of the present application, which integrates PH monitoring; Figure 3 is a structural cross-sectional view of an atrial shunt for monitoring and relieving heart failure provided by an embodiment of the present application, which integrates PH monitoring; Figure 4 is a partial circuit schematic diagram of an atrial shunt for monitoring and relieving heart failure provided by an embodiment of the present application, which integrates PH monitoring; Figure 5 is a circuit simulation verification diagram of an atrial shunt for monitoring and relieving heart failure provided by an embodiment of the present application, which integrates PH monitoring.

[0019] In the figure, 1, double cylindrical structure; 2, winding inductance; 3, through-flow hole; 4, opening and closing structure; 5, permanent magnet; 6, flange structure; 7, prefabricated groove; 8, biocompatible packaging layer; 9, pressure-sensitive capacitor; 10, control circuit; 11, planar inductance; 12, fixing rib; 13, support beam; 14, left atrial side support; 15, right atrial side support. DETAILED DESCRIPTION

[0020] In order for those skilled in the art to better understand the technical solutions of the present disclosure, the present disclosure will be further described in detail below in combination with the drawings and specific embodiments.

[0021] The embodiments of the present application will be further described in detail below in combination with the drawings and examples. The detailed description of the following examples and the drawings are used to exemplarily illustrate the principles of the present application, but cannot be used to limit the scope of the present application, i.e., the present application is not limited to the described embodiments. In the description of the present application, it should be noted that, unless otherwise specified, the meaning of "a plurality of" is two or more; the orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", "inner", "outer" and the like only serves to facilitate the description of the present application and simplify the description, and does not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the present application. In addition, the terms "first", "second" and the like are only for descriptive purposes and cannot be understood as indicating or implying relative importance. "Vertical" is not strictly vertical, but within the allowable range of error. "Parallel" is not strictly parallel, but within the allowable range of error.

[0022] In the description of the present application, it should also be noted that, unless otherwise specified and limited, the terms "mounting", "connection", "connection" should be broadly understood, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected; it can be directly connected, or indirectly connected through an intermediate medium. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0023] As shown in Figures 1-3 An atrial shunt for monitoring and relieving heart failure with integrated PH monitoring includes a main structure, a stent, an electromagnetic actuator, a composite sensor, and a control circuit.

[0024] The main structure is provided with a through-flow hole penetrating through its axial direction, and the through-flow hole is used to establish a blood flow passage between atrial chambers. The stent is arranged at the axial end of the main structure, and the stent is used to fix the main structure at the puncture hole of the heart septum.

[0025] The electromagnetic actuator comprises an open-close structure arranged in the through-flow hole, and a permanent magnet arranged in the main structure. The open-close structure comprises a plurality of movable cusp valves arranged around the through-flow hole port and having a one-way valve function. The permanent magnet is configured to drive the open-close action of the cusp valves to change the flow area of the through-flow hole.

[0026] A composite sensor is arranged in the main structure, and is configured to detect the intracardiac pressure and the pH value of the intracardiac fluid in the atrium and generate a sensing signal. A control circuit is arranged in the main structure and electrically connected to the composite sensor and the electromagnetic actuator, respectively. The control circuit is configured to control the open-close action of the electromagnetic actuator according to the received sensing signal.

[0027] In some embodiments, the cusp valve comprises a planar inductor, and a flexible membrane arranged on opposite sides of the planar inductor and connected to the main structure.

[0028] In some embodiments, the peripheral wall of the main structure is provided with a prefabricated groove, and the permanent magnet is in the shape of a circular arc and has two. The two permanent magnets are installed in the prefabricated groove in a magnet pole center-symmetrical manner to form a ring-distributed concentrated magnetic field.

[0029] In some embodiments, the control circuit comprises a rectifier bridge, a voltage stabilizing filter circuit and a switch control unit connected in sequence. The rectifier bridge and the voltage stabilizing filter circuit are used to rectify and stabilize the alternating current obtained wirelessly. The switch control unit is electrically connected to the composite sensor and the electromagnetic actuator, respectively, and is configured to control the current direction and on-off of the planar inductor according to the sensing signal.

[0030] In some embodiments, the composite sensor is a passive wireless pressure-pH composite sensor.

[0031] In some embodiments, the composite sensor comprises a wire-wound inductor, a pressure-sensitive capacitor and a pH sensing unit. The wire-wound inductor is arranged on the outer periphery of the main structure, the pressure-sensitive capacitor is arranged on the axial end of the main structure, and the pH sensing unit is arranged on the surface of the control circuit or the surface of a biocompatible packaging layer and constitutes an RLC parallel resonance circuit with the wire-wound inductor and the pressure-sensitive capacitor. The resonance frequency of the RLC parallel resonance circuit is configured to respond to the change of intracardiac pressure, and the bandwidth responds to the change of pH of intracardiac fluid.

[0032] In some embodiments, it further comprises a flange structure arranged on the axial end of the main structure, which is used to fix the wire-wound inductor to the main structure.

[0033] In some embodiments, the pressure-sensitive capacitor is a parallel-plate variable capacitor.

[0034] In some embodiments, the pH sensing unit comprises an iridium oxide or polyaniline based thin film electrode, wherein the resistance value of the thin film electrode is responsive to changes in the pH value of the intracardiac fluid.

[0035] In some embodiments, the stent is constrained within the through-flow hole in a delivery state, and the radial dimension of the stent is less than or equal to the diameter of the main structure. In a released state, the stent is deployed within the heart, and the radial dimension of the stent after deployment is greater than the diameter of the main structure and the diameter of the puncture hole.

[0036] The atrial shunt of the present application integrates pH and intracardiac pressure monitoring functions, and the through-flow hole can achieve shunting between the left atrium and the right atrium to reduce the left atrial pressure or the right atrial pressure. The cusp structure has a one-way valve function, which can effectively prevent left-to-right atrial regurgitation and avoid excessive mixing of arterial and venous blood and excessive load on the right atrium. The composite sensor can continuously monitor the intracardiac pressure to provide real-time intracardiac pressure data support. The electromagnetic actuator can dynamically adjust the opening and closing degree of the through-flow hole according to the sensing signal of the composite sensor, and realize precise and active control of the shunting effect.

[0037] Compared with traditional passive shunts, the present application can significantly reduce the risk of regurgitation and left / right heart complications while ensuring effective shunting and pressure reduction, and improve the closed-loop management capability and long-term safety of heart failure treatment. In addition, the pH sensing unit is integrated into the composite sensor to form an RLC parallel resonance system, which can realize passive and wireless synchronous monitoring of the pH value of the intracardiac fluid, provide early warning for complications such as heart failure combined with metabolic acidosis, and enhance the comprehensiveness and forward-looking of treatment.

[0038] Specifically, the present embodiment provides an atrial shunt for monitoring and relieving heart failure, which integrates PH monitoring, as shown in Figures 1-2 As shown, the first direction, the second direction and the third direction are defined to be perpendicular to each other, wherein the first direction is the X-axis direction in the Cartesian coordinate system, the second direction is the Y-axis direction in the Cartesian coordinate system, and the third direction is the Z-axis direction in the Cartesian coordinate system, and the second direction is parallel to the axial direction of the main body. The shunt comprises a main structure, a stent, a composite sensor, an electromagnetic actuator and a control circuit.

[0039] The main structure comprises a double-cylinder structure 1 and a through-flow hole 3, the double-cylinder structure 1 comprises two equal-height cylinders with different diameters stacked along the second direction axis, and the through-flow hole 3 penetrates the center of the double-cylinder structure 1 along the axis of the double-cylinder structure 1. The stent is arranged at both ends of the double-cylinder structure 1 along the second direction, and the stent comprises a left atrial stent 14 and a right atrial stent 15, which are woven by nitinol memory alloy wires and used to fix the atrial shunt as a whole in the cardiac puncture hole.

[0040] The composite sensor is a pressure-pH composite sensor structure, which adopts RLC resonance principle and includes a winding inductance 2, a pressure-sensitive capacitor 9 and a low-resistance pH sensing unit. The winding inductance 2 is fixed to the outside of the smaller cylinder of the double-cylinder structure 1, and its position is fixed by the larger cylinder and the flange structure 6. The pressure-sensitive capacitor 9 is a parallel-plate variable capacitor, which is arranged on the end face of the double-cylinder structure 1 along the positive or negative direction of the second direction. The upper plate of the pressure-sensitive capacitor 9 is combined with an elastic film, which can change the distance between the plates in response to the change of blood pressure, thereby causing the change of resonance frequency. The low-resistance pH sensing unit can be made of a conductive polymer film, which is arranged on the surface of the control circuit 10 or the outer surface of the biocompatible packaging layer 8. The resistance value of the low-resistance pH sensing unit changes with the pH value of the surrounding body fluid, which can affect the Q value of the RLC parallel resonance circuit. The in-vitro reading device can detect the shift of the resonance frequency and demodulate the pressure and pH information synchronously.

[0041] The electromagnetic actuator includes an opening and closing structure 4 and a permanent magnet 5. The opening and closing structure 4 includes a plurality of cusp structures arranged in a circumferential annular array along the through-flow hole 3, and the cross section of the cusp structure is a sandwiched structure of “flexible film-flat inductor 11-flexible film”. The flat inductor 11 specifically adopts a planar spiral inductor, and the bottom of the cusp is fixed or hinged to the edge of the side wall of the through-flow hole 3 along the positive direction of the second direction. The permanent magnet 5 includes two 1 / 4 circular arc-shaped ferrite permanent magnet pieces, which are installed in the prefabricated groove 7 of the main structure in a magnet pole center-symmetrical manner, and are used for forming a ring-distributed concentrated magnetic field to enhance the magnetic force acting on the flat inductor 11.

[0042] The control circuit 10 is electrically connected with the RLC resonance circuit of the composite sensor and the flat inductor 11 of the electromagnetic actuator, and includes a rectifier bridge, a voltage stabilizing circuit and a switching control unit, which are used for realizing energy collection, signal processing and selection and control of the opening and closing action of the opening and closing structure 4. The control circuit 10 can also include a simple impedance matching network to optimize the energy transmission and signal reading efficiency between the RLC resonance circuit and the in-vitro reader.

[0043] As shown in Figure 5 , the filter XSC4 channel A (blue) is connected to the two end ports of the RLC parallel resonance circuit, which is used for measuring the induced voltage obtained by the resonance circuit from the external coil. Channel B (green) is connected to the rear port of the rectifier bridge, which is used for measuring the output DC voltage of the rectifier bridge. XSC1 (red) is connected to the ends of the current-limiting resistor R1 (as shown in Figure 4 ) with a resistance of 0.1 Ω, which is used for calculating the load current of the flat inductor 11 in combination with the resistance value of the current-limiting resistor. The simulation results show that the circuit can obtain energy by coupling with the external coil and drive the inductive load with small voltage and large current.

[0044] The integrated pH and intracardiac pressure monitoring and heart failure relieving atrial shunt provided by the embodiment can realize left atrium to right atrium shunt to reduce left atrial pressure. The cusp structure has a one-way valve function in a natural state, which can effectively prevent blood reflux. The composite sensor can continuously monitor the intracardiac pressure, and the control circuit 10 drives the electromagnetic actuator according to the sensing signal of the composite sensor to dynamically adjust the effective flow area of the flow hole 3, so as to realize precise and active control of the shunt effect, thereby reducing the left heart load while avoiding excessive right heart load, and improving the safety and effectiveness of treatment.

[0045] Specifically, as shown in Figure 1 and Figure 2 , the flange structure 6 is located at the negative end of the double-cylinder structure 1 along the second direction, which is used to fix the wire-wound inductor 2. The bracket is in a stretched state along the second direction before release, and restores to an umbrella shape after release under the action of body temperature, which has a diameter greater than the diameter of the main structure and the diameter of the heart puncture hole, so as to realize reliable anchoring.

[0046] Referring to Figure 2 , the permanent magnet 5 is arranged in the prefabricated groove 7 through the fixing rib 12, and the two groove walls opposite to each other are supported and connected through the support beam 13.

[0047] As shown in Figure 3 , the permanent magnet 5 is installed in the prefabricated groove 7, and the annular magnetic field generated thereby can enhance the efficiency of wireless coupling with the extracorporeal device. The planar inductor 11 can generate an additional force to open or close the cusp under the action of the magnetic field after being energized, thereby enhancing or weakening the shunt effect of the flow hole 3.

[0048] It should be noted that the second direction positive direction in the embodiment generally points to the left atrium side, and the second direction negative direction points to the right atrium side. The installation surface (top surface or bottom surface) of the pressure-sensitive capacitor 9 determines the adjustment logic preference of the system, for example, focusing on monitoring left atrial pressure or peak ejection pressure, but the core control principle is the same. The arrangement of the permanent magnet 5 needs to ensure that all devices use the same magnetic field direction (clockwise or counterclockwise) to ensure the consistency of the control circuit 10 driving logic.

[0049] It can be understood that the above embodiments are only exemplary embodiments adopted for illustrating the principles of the present disclosure, but the present disclosure is not limited thereto. Various modifications and improvements can be made by those skilled in the art without departing from the spirit and essence of the present disclosure, and these modifications and improvements are also considered as the protection scope of the present disclosure.

Claims

1. An integrated PH monitoring atrial shunt for monitoring and relieving heart failure, characterized by, The application relates to a main structure provided with a through-flow hole penetrating through the axial direction of the main structure, the through-flow hole being used for establishing a blood flow channel of an atrium; a support arranged at the axial end of the main structure, the support being used for fixing the main structure to a puncture hole of a cardiac septum; an electromagnetic actuator comprising an opening and closing structure arranged in the through-flow hole in an openable and closable mode, the opening and closing structure comprising a plurality of movable sharp petals provided with a one-way valve function and arranged at the port of the through-flow hole, and a permanent magnet arranged on the main structure, the permanent magnet being configured to drive the opening and closing action of the sharp petals to change the flow area of the through-flow hole; a composite sensor arranged on the main structure, the composite sensor being used for detecting the intracardiac pressure and the pH value of intracardiac liquid in the atrium and generating a sensing signal; and a control circuit arranged on the main structure and electrically connected with the composite sensor and the electromagnetic actuator respectively, the control circuit being configured to control the opening and closing action of the electromagnetic actuator according to the received sensing signal. The sharp petals comprise a planar inductor and a flexible film arranged on the opposite sides of the planar inductor and connected with the main structure. The peripheral wall of the main structure is provided with a prefabricated groove, the permanent magnet is in the shape of a circular arc and is provided with two, and the two permanent magnets are installed in the prefabricated groove in a magnet pole center symmetrical mode to form a ring-distributed concentrated magnetic field. The control circuit comprises a rectifier bridge, a voltage stabilizing filter circuit and a switch control unit connected in sequence, the rectifier bridge and the voltage stabilizing filter circuit are used for rectifying and stabilizing alternating current obtained wirelessly, and the switch control unit is electrically connected with the composite sensor and the electromagnetic actuator respectively and is configured to control the current direction and on-off of the planar inductor according to the sensing signal. The composite sensor is a passive wireless pressure-pH composite sensor. The composite sensor comprises a wire-wound inductor, a pressure-sensitive capacitor and a pH sensing unit, the wire-wound inductor is arranged on the outer periphery of the main structure, the pressure-sensitive capacitor is arranged at the axial end of the main structure, and the pH sensing unit is arranged on the surface of the control circuit or the surface of a biocompatible packaging layer and constitutes an RLC parallel resonance circuit with the wire-wound inductor and the pressure-sensitive capacitor, and the resonance frequency of the RLC parallel resonance circuit is configured to respond to the intracardiac pressure change, and the bandwidth thereof responds to the pH change of the intracardiac liquid.

2. An integrated PH monitoring atrial shunt for monitoring and relieving heart failure according to claim 1, characterized in that, The application further comprises a flange structure arranged at the axial end of the main structure, the flange structure being used for fixing the wire-wound inductor to the main structure.

3. An integrated PH monitoring atrial shunt for monitoring and relieving heart failure according to claim 2, characterized in that, The pressure-sensitive capacitor is a parallel-plate variable capacitor.

4. An integrated PH monitoring atrial shunt for monitoring and relieving heart failure according to claim 2, characterized in that, The pH sensing unit comprises an iridium oxide or polyaniline-based thin film electrode, and the resistance value of the thin film electrode responds to the pH value change of the intracardiac liquid.

5. An integrated PH monitoring atrial shunt for monitoring and relieving heart failure according to claim 1, wherein, The support is constrained in the through-flow hole in a delivery state, and the radial dimension of the support is less than or equal to the diameter of the main structure; in a release state, the support is unfolded in the heart, and the radial dimension of the unfolded support is greater than the diameter of the main structure and the diameter of the puncture hole.

6. An integrated PH monitoring atrial shunt for monitoring and relieving heart failure according to claim 1, characterized in that, ​ 7. An integrated PH monitoring atrial shunt for monitoring and relieving heart failure according to claim 6, characterized in that, ​ 8. The integrated PH monitoring atrial shunt for monitoring and mitigating heart failure of claim 6, wherein, ​ 9. An integrated PH monitoring atrial shunt for monitoring and relieving heart failure according to claim 6, wherein, ​ 10. The integrated PH monitoring atrial shunt for monitoring and relieving heart failure of claim 1, wherein, ​

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