Sterile filling and plugging machine for preparing animal vaccines

Abstract

The invention relates to the technical field of animal vaccine preparation, and discloses a sterile filling and plugging machine for preparing animal vaccine.The sterile filling and plugging machine comprises a rack, and a filling piece and a plugging piece are installed on the rack; the conveying assembly comprises a rotating disc and an adjusting part, the rotating disc is rotationally connected to the rack, a plurality of penicillin bottles are stored in the rotating disc, the height of the penicillin bottles is adjusted through the adjusting part, and the filling part and the plugging part are located on the two sides of the rotating disc respectively and used for conducting filling and plugging on the penicillin bottles; the plurality of shielding pieces are arranged on the rotating disc in the circumferential direction, and after the penicillin bottles are filled, the shielding pieces shield the penicillin bottles; and the output assembly comprises a screening piece and an output piece, the output piece is arranged on the rack and used for receiving the penicillin bottles with the plugs, and the screening piece is arranged on the output piece and used for screening the penicillin bottles. The device is small in occupied area, vaccine pollution is avoided, and the vaccine product quality is guaranteed.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of animal vaccine preparation, and particularly relates to a sterile filling and capping machine for preparing an animal vaccine. BACKGROUND

[0002] In the production process of an animal vaccine, filling and capping are crucial processes, which must be carried out in a sterile environment with high cleanliness to prevent the drug from being contaminated. The traditional filling and capping equipment usually adopts linear conveying, has a large equipment footprint, and the exposure time of a vial is relatively long during the transfer between stations, thereby increasing the risk of contamination.

[0003] In addition, in the existing equipment, the bottle opening is usually in an open state after filling until entering the capping station, and during this period, particles and microorganisms in the environment may fall into the bottle, causing the vaccine to be contaminated. In the output link, there is a lack of online detection function for the capping quality (such as whether the stopper is installed in place), and the defective products may flow into the subsequent process.

[0004] Therefore, there is an urgent need for a sterile filling and capping machine for preparing an animal vaccine to solve the above problems. SUMMARY

[0005] The present application aims to provide a sterile filling and capping machine for preparing an animal vaccine to solve the problems existing in the prior art.

[0006] To achieve the above-mentioned purpose, the present application provides the following scheme: the present application provides a sterile filling and capping machine for preparing an animal vaccine, comprising:

[0007] a rack, a filling part and a capping part are installed on the rack;

[0008] a conveying assembly, comprising a turntable and an adjusting part, the turntable is rotationally connected to the rack, a plurality of vials are stored in the turntable, the height of the vials is adjusted by the adjusting part, and the filling part and the capping part are located on the two sides of the turntable for filling and capping the vials;

[0009] a plurality of shielding parts are circumferentially arranged on the turntable, and the shielding parts shield the vials after the vials are filled;

[0010] an output assembly, comprising a screening part and an output part, the output part is arranged on the rack for receiving the capped vials, and the screening part is arranged on the output part for screening the vials.

[0011] Preferably, a plurality of placing grooves are arranged on the rotating disc in the circumferential direction, vertical grooves are arranged on opposite side walls of the placing grooves, first sealing pipes are fixedly connected to inner top ends of the vertical grooves, first sealing blocks are slidably connected into the first sealing pipes, one end of a first connecting rod is fixedly connected to the first sealing block, the other end of the first connecting rod extends out of the first sealing pipe and is fixedly connected to an arc-shaped clamping plate, and the penicillin bottle is located between the two arc-shaped clamping plates.

[0012] Preferably, the adjusting member comprises a plurality of support rings, the support rings are fixedly connected to the bottom end of the rotating disc in the circumferential direction and correspond to the placing grooves one by one, a slide rod is slidably connected to the support ring, a top block is fixedly connected to the top end of the slide rod, second connecting rods are fixedly connected to both ends of the top block, a second sealing pipe is fixedly connected to the bottom of the vertical groove, a second sealing block is fixedly connected to one end of the second connecting rod extending into the second sealing pipe, the second sealing pipe is in communication with the first sealing pipe, and a lifting member is arranged on the rack and used for controlling the lifting of the slide rod.

[0013] Preferably, the lifting member comprises a fixed ring fixedly connected to the rack, protrusions are arranged on both top ends of the fixed ring, a pulley is arranged on the bottom end of the slide rod, and the pulley is in contact with the top end of the fixed ring.

[0014] Preferably, a spring is sleeved on the slide rod, and both ends of the spring are fixedly connected with the fixed ring and the pulley, respectively.

[0015] Preferably, the shielding member comprises an air outlet mounted on the top end of the placing groove in the circumferential direction, the air outlet is in communication with an external air filtering module, and the air outlet is used for forming a sterile air flow at the top end of the placing groove.

[0016] Preferably, the output member comprises a conveying table fixedly connected to the rack, two conveying belts are arranged on the conveying table, baffles are fixedly connected to the conveying belts in the circumferential direction, the baffles on the two conveying belts correspond to each other, the gap between the placing grooves and the two conveying belts corresponds to the placing grooves, and a pneumatic cylinder is arranged in the placing groove, an output end of the pneumatic cylinder is fixedly connected with a push plate, and the push plate is used for pushing the penicillin bottle to the conveying belt.

[0017] Preferably, the screening member comprises a detection module fixedly connected to the conveying table, and the detection module is used for monitoring the stopper.

[0018] Preferably, the filling member comprises a filling needle mounted on the rack, and the filling needle is in communication with external liquid medicine through a peristaltic pump.

[0019] Preferably, the capping device comprises a hydraulic cylinder and a mechanical hand, the hydraulic cylinder and the mechanical hand are fixedly connected to the frame, the mechanical hand is used for transferring the bottle plug, the output end of the hydraulic cylinder is used for extruding the bottle plug, and the output end of the hydraulic cylinder is provided with a pressure sensor.

[0020] Compared with the prior art, the application has the following advantages and technical effects:

[0021] The application provides a sterile filling and capping machine for preparing animal vaccines, when in use, the bottles are placed on the rotating disc and rotate with the rotating disc, are lifted for filling at the filling part, are lowered and stored in the rotating disc after filling, air flow is blocked by the shielding part, external pollutants are prevented from entering, are lifted for capping at the capping part, are output by the output part after capping, and are detected by the screening part during the output process, and the products with unqualified capping are screened out. The application has small occupied area, avoids vaccine pollution, and guarantees the quality of vaccine products. BRIEF DESCRIPTION OF DRAWINGS

[0022] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiments. Obviously, the drawings in the following description only show some embodiments of the present application, and for those skilled in the art, other drawings can also be obtained from these drawings without creative labor:

[0023] Figure 1 It is a schematic diagram of the overall structure of the present application;

[0024] Figure 2 It is a schematic diagram of the output part structure of the present application;

[0025] Figure 3 It is a schematic diagram of the output part structure of the present application; Figure 2 It is a partial enlarged view of A in the present application;

[0026] Figure 4 It is a partial enlarged view of B in the present application; Figure 2 It is a partial enlarged view of B in the present application;

[0027] Figure 5 It is a schematic diagram of the adjusting part structure of the present application;

[0028] 1, rack; 2, turntable; 3, a vial; 4, placing groove; 5, vertical groove; 6, first sealing pipeline; 7, first sealing block; 8, first connecting rod; 9, arc clamping plate; 10, support ring; 11, slide bar; 12, top block; 13, second connecting rod; 14, second sealing pipeline; 15, second sealing block; 16, fixed ring; 17, protrusion; 18, pulley; 19, air outlet; 20, air filter module; 21, conveying belt; 22, baffle; 23, air cylinder; 24, push plate; 25, detection module; 26, filling needle; 27, peristaltic pump; 28, hydraulic cylinder; 29, pressure sensor; 30, spring; 31, conveying table. DETAILED DESCRIPTION

[0029] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all the other embodiments obtained by those skilled in the art without creative work fall within the protection scope of the present application.

[0030] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the present application will be further described in detail below with reference to the drawings and specific embodiments.

[0031] Animal vaccines are products prepared from pathogenic microorganisms with good immunogenicity after propagation and treatment. After inoculation into the animal body, the animal body produces specific antibodies, and when the antibody titer in the body reaches a certain value, the animal body can resist the invasion and infection of the pathogenic microorganisms, thereby playing a role in preventing diseases. In the preparation process of animal vaccines, a sterile tank is needed to load and plug the animal vaccines.

[0032] The related technology discloses a kind of sterile filling and stoppering machines for preparing animal vaccine, including operation platform, the lower end of operation platform is fixedly installed with support frame, the lower end of support frame is fixedly installed with rubber pad, the upper end of operation platform is connected with rotating mechanism in middle part, the lower part of rotating mechanism is fixedly installed with support frame, the upper end left side of operation platform is fixedly installed with fixed frame, the lower end right side of fixed frame is connected with transmission mechanism, the upper end right side of transmission mechanism is connected with stoppering mechanism, stoppering mechanism is slidably installed with transmission mechanism, the upper end rear part of operation platform is fixedly installed with bottle plug placing table, the upper end of bottle plug placing table is provided with bottle plug, the front end left side of operation platform is fixedly installed with control panel, rotating mechanism is provided with multiple filling bottles.The sterile filling and stoppering machine for preparing animal vaccine can clamp and fix different sizes of filling bottles, is firm, has high versatility, and the stoppering force can be controlled conveniently, and processing is efficient.In the above related technology, after filling, the bottle mouth is usually in an open state until it enters the stoppering station, and during this period, particles and microorganisms in the environment can fall into the bottle, causing contamination of the vaccine, and there is no online detection function for whether the bottle plug is installed in place in the output link, and defective products can flow into subsequent processes.In order to solve the above problems, the present application provides the following scheme:

[0033] Reference Figures 1-5 The present application provides a kind of sterile filling and stoppering machines for preparing animal vaccine, comprising:

[0034] Frame 1, filling part and stoppering part are installed on frame 1;

[0035] Conveying assembly, including rotating disc 2 and adjusting part, rotating disc 2 is rotatably connected to frame 1, rotating disc 2 stores several test tubes 3, the height of test tube 3 is adjusted by adjusting part, filling part and stoppering part are located on both sides of rotating disc 2 for filling and stoppering test tube 3;

[0036] Several shielding parts are circumferentially arranged on rotating disc 2, and shielding parts shield test tube 3 after filling;

[0037] Output assembly, including screening part and output part, output part is arranged on frame 1 for receiving stoppered test tube 3, and screening part is arranged on output part for screening test tube 3.

[0038] In one embodiment of the present application, in use, test tube 3 is placed on rotating disc 2 and rotates with rotating disc 2, rises to fill at filling part, and after filling, is lowered and stored in rotating disc 2, and is shielded by the shielding part to prevent external pollutants from entering, rises to stopper at stoppering part, and after stoppering, is connected to output part for output, and is detected by screening part during output process to screen out unqualified products.

[0039] As an optional implementation, a plurality of placing grooves 4 are formed on the rotating disc 2 in the circumferential direction, vertical grooves 5 are formed on opposite side walls in each of the placing grooves 4, a first sealing pipe 6 is fixedly connected to the inner top of each of the vertical grooves 5, a first sealing block 7 is slidably connected in the first sealing pipe 6, one end of a first connecting rod 8 is fixedly connected to the first sealing block 7, the other end of the first connecting rod 8 extends out of the first sealing pipe 6 and is fixedly connected to an arc-shaped clamping plate 9, and the vial 3 is located between the two arc-shaped clamping plates 9.

[0040] In one embodiment of the present application, when in use, the vial 3 is pushed into the placing groove 4 and rotates with the rotating disc 2, and when the vial 3 rotates to the filling and stoppering position, the arc-shaped clamping plate 9 is arranged to clamp the vial 3.

[0041] As an optional implementation, the adjusting member includes a plurality of support rings 10, the plurality of support rings 10 are fixedly connected to the bottom end of the rotating disc 2 in the circumferential direction and correspond to the plurality of placing grooves 4 one by one, a slide rod 11 is slidably connected to each of the support rings 10, a top block 12 is fixedly connected to the top end of the slide rod 11, a second connecting rod 13 is fixedly connected to both ends of the top block 12, a second sealing pipe 14 is fixedly connected to the bottom of each of the vertical grooves 5, a second sealing block 15 is fixedly connected to one end of the second connecting rod 13 extending into the second sealing pipe 14, the second sealing pipe 14 is in communication with the first sealing pipe 6, and a lifting member is arranged on the rack 1 and used to control the lifting of the slide rod 11.

[0042] In one embodiment of the present application, when the slide rod 11 is lifted, the vial 3 is lifted, the second sealing block 15 is arranged to extrude air to drive the first sealing block 7 to move, and thus the clamping of the vial 3 is controlled, and the stability of the vial 3 is ensured during the filling and stoppering.

[0043] As an optional implementation, the lifting member includes a fixed ring 16 fixedly connected to the rack 1, protrusions 17 are arranged at the top ends of both sides of the fixed ring 16, a pulley 18 is mounted at the bottom end of the slide rod 11, and the pulley 18 is arranged in contact with the top end of the fixed ring 16.

[0044] In one embodiment of the present application, the positions of the two protrusions 17 correspond to the filling and stoppering points, the slide rod 11 is lifted by the contact between the pulley 18 and the protrusion 17, and conversely, the slide rod 11 is in a horizontal state and in contact with the fixed ring 16, at this time, the vial 3 is located in the placing groove 4 and will not be lifted.

[0045] As an optional implementation, a spring 30 is sleeved on the slide rod 11, and the spring 30 is fixedly connected to the fixed ring 16 and the pulley 18 at both ends, respectively.

[0046] In one embodiment of the present application, the spring 30 provides a buffer, makes the pulley 18 more stable, and ensures the reset of the slide rod 11.

[0047] As an optional implementation, the shielding member comprises an air outlet 19 installed at the top end of the placing groove 4 in a circumferential direction, the air outlet 19 is communicated with an external air filtering module 20, and the air outlet 19 is used to form a sterile air flow at the top end of the placing groove 4.

[0048] In an embodiment of the present application, a vertical downward sterile air flow curtain (such as laminar air flow) is formed above the bottle mouth through the air outlet 19 after filling and before stoppering, so that the pollutants in the surrounding environment are effectively isolated, and continuous positive pressure sterile protection is provided for the opening stage of the penicillin bottle, thereby greatly reducing the product pollution risk.

[0049] As an optional implementation, the output member comprises a conveying table 31 fixedly connected to the rack 1, two conveying belts 21 are installed on the conveying table 31, the conveying belts 21 are fixedly connected with baffles 22 in a circumferential direction, the baffles 22 on the two conveying belts 21 are one-to-one corresponding, the gap between the placing groove 4 and the two conveying belts 21 is corresponding, and a pneumatic cylinder 23 is arranged in the placing groove 4. The output end of the pneumatic cylinder 23 is fixedly connected with a push plate 24, and the push plate 24 is used to push the penicillin bottle 3 to the conveying belt 21.

[0050] In an embodiment of the present application, the conveying belt 21 cooperates with the baffle 22 to orderly transfer the stoppered penicillin bottle 3 from the rotating disc 2 to the next process, and the conveying is stable.

[0051] As an optional implementation, the screening member comprises a detection module 25 fixedly connected to the conveying table 31, and the detection module 25 is used to monitor the stopper.

[0052] In an embodiment of the present application, the detection module 25 (such as a visual sensor or a mechanical measuring device) is arranged, so that the stoppered penicillin bottle 3 can be monitored in real time on line, and unqualified products such as missing stoppers and improper installation of stoppers can be automatically screened out, thereby improving the quality consistency of the final product and the intelligent level of production.

[0053] As an optional implementation, the filling member comprises a filling needle 26 installed on the rack 1, and the filling needle 26 is communicated with external liquid medicine through a peristaltic pump 27.

[0054] In an embodiment of the present application, the peristaltic pump 27 is used for filling, so that the high precision of liquid medicine metering is ensured.

[0055] As an optional implementation, the stoppering member comprises a hydraulic cylinder 28 and a mechanical hand, the hydraulic cylinder 28 and the mechanical hand are both fixedly connected to the rack 1, the mechanical hand is used to transfer the stopper, the output end of the hydraulic cylinder 28 is used to extrude the stopper, and the output end of the hydraulic cylinder 28 is provided with a pressure sensor 29.

[0056] In one embodiment of the present application, the capping device uses hydraulic cylinder 28 in cooperation with pressure sensor 29 to accurately control the capping pressure, ensuring that each bottle cap is pressed into place and will not damage the bottle or cap due to excessive pressure, thus ensuring the reliability of the capping quality.

[0057] In the description of the present application, it should be understood that the terms "longitudinal", "transverse", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the present application.

[0058] The above-described embodiments are only preferred modes of the present application and are not intended to limit the scope of the present application, and various modifications and improvements to the technical solutions of the present application made by those skilled in the art without departing from the design spirit of the present application shall fall within the protection scope of the present application as defined by the claims.

Claims

1. A sterile filling and capping machine for preparing animal vaccines, characterized in that, include: A frame (1) on which filling components and stopper components are mounted; The conveying assembly includes a turntable (2) and an adjusting component. The turntable (2) is rotatably connected to the frame (1). The turntable (2) contains a number of vials (3). The height of the vials (3) is adjusted by the adjusting component. The filling component and the stoppering component are located on both sides of the turntable (2) for filling and stoppering the vials (3). Several shielding components are arranged circumferentially on the turntable (2). When the vial (3) is filled, the shielding components shield the vial (3). The output component includes a filter and an output component, the output component being disposed on the frame (1) for receiving the stoppered vials (3), and the filter being disposed on the output component for filtering the vials (3).

2. The aseptic filling and capping machine for preparing animal vaccines according to claim 1, characterized in that: The turntable (2) has several placement slots (4) along its circumference. Vertical grooves (5) are provided on the opposite side walls of each placement slot (4). A first sealing pipe (6) is fixedly connected to the top of the vertical groove (5). A first sealing block (7) is slidably connected inside the first sealing pipe (6). One end of a first connecting rod (8) is fixedly connected to the first sealing block (7). The other end of the first connecting rod (8) extends out of the first sealing pipe (6) and is fixedly connected to an arc-shaped clamping plate (9). The vial (3) is located between the two arc-shaped clamping plates (9).

3. The aseptic filling and capping machine for preparing animal vaccines according to claim 2, characterized in that: The adjusting component includes several support rings (10), which are fixedly connected to the bottom of the turntable (2) along the circumference and correspond one-to-one with several placement slots (4). A slide rod (11) is slidably connected to the support ring (10), and a top block (12) is fixedly connected to the top of the slide rod (11). A second connecting rod (13) is fixedly connected to both ends of the top block (12). A second sealing pipe (14) is fixedly connected to the bottom of the vertical groove (5). One end of the second connecting rod (13) extends into the second sealing pipe (14) and is fixedly connected to a second sealing block (15). The second sealing pipe (14) is connected to the first sealing pipe (6). A lifting component is provided on the frame (1), which is used to control the lifting of the slide rod (11).

4. The aseptic filling and capping machine for preparing animal vaccines according to claim 3, characterized in that: The lifting component includes a fixed ring (16) fixedly connected to the frame (1). The top of both sides of the fixed ring (16) are provided with protrusions (17). The bottom of the slide rod (11) is equipped with a pulley (18), and the pulley (18) is in contact with the top of the fixed ring (16).

5. The aseptic filling and capping machine for preparing animal vaccines according to claim 4, characterized in that: A spring (30) is fitted on the slide rod (11), and the two ends of the spring (30) are fixedly connected to the fixed ring (16) and the pulley (18) respectively.

6. The aseptic filling and capping machine for preparing animal vaccines according to claim 2, characterized in that: The shielding component includes an air outlet (19) installed circumferentially at the top of the placement slot (4), the air outlet (19) being connected to an external air filtration module (20) for forming a sterile airflow at the top of the placement slot (4).

7. The aseptic filling and capping machine for preparing animal vaccines according to claim 2, characterized in that: The output component includes a conveyor platform (31) fixedly connected to the frame (1). Two conveyor belts (21) are installed on the conveyor platform (31). Baffles (22) are fixedly connected to the conveyor belts (21) along the circumferential direction. Several baffles (22) on the two conveyor belts (21) correspond one to one. The gap between the placement groove (4) and the two conveyor belts (21) corresponds. A cylinder (23) is provided in the placement groove (4). A push plate (24) is fixedly connected to the output end of the cylinder (23). The push plate (24) is used to push the vial (3) towards the conveyor belt (21).

8. The aseptic filling and capping machine for preparing animal vaccines according to claim 7, characterized in that: The screening component includes a detection module (25) fixedly connected to the conveyor (31), and the detection module (25) is used to monitor the bottle stopper.

9. The aseptic filling and capping machine for preparing animal vaccines according to claim 1, characterized in that: The filling component includes a filling needle (26) mounted on the frame (1), and the filling needle (26) is connected to the external liquid medicine through a peristaltic pump (27).

10. The aseptic filling and capping machine for preparing animal vaccines according to claim 1, characterized in that: The stopper assembly includes a hydraulic cylinder (28) and a robotic arm. Both the hydraulic cylinder (28) and the robotic arm are fixedly connected to the frame (1). The robotic arm is used to transfer the stopper. The output end of the hydraulic cylinder (28) is used to squeeze the stopper. A pressure sensor (29) is installed at the output end of the hydraulic cylinder (28).

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