Traditional Chinese medicine formula capable of losing weight and application thereof

Abstract

The invention discloses a traditional Chinese medicine formula capable of losing weight and application thereof, and belongs to the technical field of traditional Chinese medicine weight losing. According to the traditional Chinese medicine formula, on the basis of 1000 ml of a finished product preparation, the traditional Chinese medicine formula contains 80-100 g of cortex albiziae, 100-120 g of cortex lycii radicis and other core components, 40-50 g of moutan bark and other auxiliary components, and 100-150 ml of table vinegar, 80-100 g of honey and other blending auxiliary materials. The preparation method comprises the following steps: processing the raw materials, performing water decoction and vinegar extraction, refining, filtering, concentrating, blending, sterilizing and filling to obtain a liquid preparation. The core component synergistically promotes lipolysis, the pericarpium citri reticulatae and the vinegar synergistically prolong gastric emptying time to generate satiety, and two-dimensional weight loss of'reducing intake and promoting metabolism 'is realized. The formula is mild in medicine property, the occurrence rate of adverse reaction is only 5%, and the liquid dosage form is quick to absorb, convenient to take and suitable for people with various constitutions and has the effects of reducing weight and conditioning.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine formulas, specifically to a traditional Chinese medicine formula for weight loss and its application. Background Technology

[0002] With changing lifestyles, the incidence of obesity and related metabolic diseases is rising year by year, making weight loss a health concern for the entire population. Current weight loss techniques are mainly divided into four categories: chemical drugs, Western medicine preparations, traditional Chinese medicine, and dietary therapy. Chemical drugs and Western medicine preparations often contain ingredients such as orlistat, which may result in significant short-term weight loss, but are prone to causing adverse reactions such as gastrointestinal damage, abnormal liver and kidney function, and insomnia, making their safety difficult to guarantee. Dietary therapy, on the other hand, has the problem of mild effects and slow onset of action, making it difficult to meet the demand for rapid weight loss.

[0003] Traditional Chinese medicine is widely used in the weight loss field due to its "safe and mild" characteristics. However, existing Chinese medicine weight loss formulas still have many shortcomings: First, the formula design relies heavily on experience, and the core ingredients are not clearly defined. For example, some formulas use only a single herb as the main ingredient, lacking synergistic design, resulting in unstable weight loss effects. Second, the medicinal properties are too biased. For example, long-term use of cold herbs can easily damage the spleen and stomach's yang energy, leading to loss of appetite, while warm and drying herbs can easily cause symptoms of internal heat. Third, the dosage forms are mostly pills or decoctions. Pills have slow dissolution of active ingredients, and decoctions are inconvenient to take and difficult to control dosage. Moreover, most formulas do not address the core pain points of "easy hunger and difficulty in sticking to the regimen," resulting in poor user compliance.

[0004] Furthermore, existing traditional Chinese medicine (TCM) weight loss formulas often neglect the need for simultaneous weight loss and conditioning, focusing solely on decreasing weight, which can easily lead to metabolic disorders or rebound weight gain. Therefore, developing a TCM weight loss program with a scientifically formulated recipe, clearly defined core ingredients, mild and safe properties, convenient dosage form, and the ability to balance weight loss and dietary control has become an urgent technical challenge and is of great significance for promoting the development of TCM weight loss technology. Summary of the Invention

[0005] The technical problem to be solved by the present invention is to overcome the defects of the above-mentioned technology and provide a traditional Chinese medicine formula for weight loss and slimming and its application.

[0006] To solve the above-mentioned technical problems, the technical solution provided by the present invention is a traditional Chinese medicine formula for weight loss and its application: a traditional Chinese medicine formula for weight loss, characterized in that:

[0007] The traditional Chinese medicine formula, based on a 1000ml finished preparation, includes the following components by weight or volume: core active ingredients 80-100g Albizia bark, 100-120g Lycium bark, and 60-80g Mulberry bark; auxiliary regulating ingredients 40-50g Moutan bark, 20-30g Cinnamon bark, and 50-60g Tangerine peel; blending excipients 100-150ml edible vinegar and 80-100g honey; and solvent purified water, the amount of which is to be made up to 1000ml.

[0008] As an improvement, the vinegar is aged vinegar and the honey is acacia honey.

[0009] As an improvement, based on the dosage range of 100-150ml of edible vinegar and 80-100g of honey in the traditional Chinese medicine formula, the dosage ratio of edible vinegar to honey is 1:(0.8-1). This ratio can achieve the dual effect of flavor harmony and mild medicinal properties.

[0010] The preparation process of a traditional Chinese medicine formula for weight loss includes the following steps:

[0011] Raw material pretreatment: Screen and remove impurities and non-medicinal parts from the Albizia bark, Lycium bark, Mulberry bark, Peony bark, Cinnamon bark, and Dried tangerine peel; wash and pulverize to 20-40 mesh coarse powder; let the edible vinegar stand for 24 hours to remove sediment; melt the honey in a 50℃ water bath and filter to remove impurities.

[0012] Double extraction: Put the crude powder of the Chinese medicinal materials into the extraction tank, add 8 times the amount of purified water and soak for 30 minutes. After boiling, extract by simmering for 1.5 hours and collect the first extract. Add 6 times the amount of purified water to the residue and extract by simmering again for 1 hour. Collect the second extract and combine them. Mix the residue with 4 times the amount of edible vinegar and extract at a constant temperature of 50-60℃ for 1 hour. Collect the vinegar extract.

[0013] Refining filtration: Combine the extract and the acetic acid extract, coarsely filter through a 200-mesh filter cloth, centrifuge at 3000 r / min for 15 minutes, and then finely filter through a 0.45 μm microporous membrane;

[0014] Concentration and blending: Concentrate the filtrate to 500-600ml at 60-70℃ and vacuum degree -0.08MPa. After cooling to below 40℃, add the remaining edible vinegar and processed honey, stir well, and add purified water to make up to 1000ml. Adjust the pH value to 4.0-5.0.

[0015] Sterilization and filling: Sterilize the mixed preparation by keeping it at 70-80℃ for 30 minutes, and then fill and seal it under aseptic conditions after cooling.

[0016] As an improvement, the edible vinegar used for extraction in step 2 accounts for 60% of the total amount of edible vinegar used, and the edible vinegar added in step 4 accounts for 40% of the total amount of edible vinegar used.

[0017] As an improvement, the preparation process also includes a quality control step: the finished product is a clear brown liquid, with a total saponin content of not less than 0.5g per 20ml, a total bacterial count of ≤100cfu / ml, mold and yeast counts of ≤10cfu / ml, and no pathogenic bacteria detected.

[0018] The weight loss and slimming traditional Chinese medicine preparation prepared by the preparation process is in liquid dosage form. The traditional Chinese medicine preparation has the effects of promoting fat decomposition, prolonging gastric emptying time and producing a feeling of fullness.

[0019] As an improvement, the traditional Chinese medicine preparation is to be taken twice a day, 20ml each time.

[0020] The application of traditional Chinese medicine formulas in the preparation of weight loss products, which are presented in liquid dosage form, achieves a dual-dimensional weight loss effect of "reducing intake" and "promoting metabolism" by synergistically promoting fat decomposition with core active ingredients, optimizing metabolism with auxiliary regulatory ingredients, and prolonging gastric emptying time with excipients. Moreover, the weight loss products are mild in nature and suitable for long-term use by people of all constitutions.

[0021] The application of traditional Chinese medicine preparations in regulating glucose and lipid metabolism and reducing food intake involves the synergistic regulation of glucose and lipid metabolism by betaine from Lycium chinense root bark, saponins from Albizia julibrissin bark, and flavonoids from Morus alba root bark, which inhibits the activity of lipase. At the same time, the volatile oil of Citrus reticulata peel and the acidic components of edible acetic acid work together to prolong gastric emptying time, thereby reducing food intake. The traditional Chinese medicine preparations mentioned in this application will not damage the spleen and stomach function of the human body.

[0022] The advantages of this invention compared to existing technologies are as follows: Its core advantage lies in constructing a dual-dimensional synergistic weight loss system that combines "reduced intake + promoted metabolism," addressing the core pain points of weight loss. Among the core active ingredients, betaine from Lycium chinense root bark inhibits fat synthesis, Lycium chinense root bark extract promotes fat decomposition, Albizia julibrissin bark saponins improve insulin resistance, and Morus alba root bark flavonoids inhibit fat cell proliferation; these four ingredients synergistically enhance metabolic regulation. The volatile oils of Citrus reticulata peel and the acidic components of edible acetic acid prolong gastric emptying time, combined with Albizia julibrissin bark saponins to inhibit orexin secretion, creating a lasting feeling of fullness. In a 30-day experiment, the experimental group experienced an average weight loss of 5.3 kg and a 3.2% decrease in body fat percentage.

[0023] In terms of safety, it follows the traditional Chinese medicine concept of "balancing cold and heat". Cinnamon is used to balance the cold nature of Lycium bark and mulberry bark, and tangerine peel and honey are added to protect the spleen and stomach. Edible vinegar and honey are both food and medicine ingredients with no risk of chemical additives. The incidence of adverse reactions in the experimental group was only 5%, which is far lower than the 55% of commercially available chemical weight loss products.

[0024] The liquid dosage form is processed using a "water decoction + vinegar extraction" process, ensuring complete dissolution of the active ingredients and resulting in absorption 3-5 times faster than the solid dosage form. The convenient 20ml single-dose packaging enhances patient compliance. It also incorporates traditional Chinese medicine principles to alleviate obesity-related symptoms such as limb heaviness. Furthermore, the raw materials are readily available, the process is mature, and the cost per 1000ml is only 80-100 yuan, making it extremely valuable for industrialization. Attached Figure Description

[0025] Figure 1 This is a diagram of a traditional Chinese medicine formula for weight loss and slimming according to the present invention.

[0026] Figure 2 This is a diagram illustrating the preparation process of the traditional Chinese medicine formula for weight loss and slimming according to the present invention. Detailed Implementation

[0027] To facilitate understanding of this application, a more complete description will be provided below with reference to the accompanying drawings, which illustrate embodiments of the present application. However, the present application can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided so that the disclosure of this application will be thorough and complete.

[0028] Referring to the attached diagram, a traditional Chinese medicine formula for weight loss and its application are described. The formula is characterized by:

[0029] The traditional Chinese medicine formula, based on a 1000ml finished preparation, includes the following components by weight or volume: core active ingredients 80-100g Albizia bark, 100-120g Lycium bark, and 60-80g Mulberry bark; auxiliary regulating ingredients 40-50g Moutan bark, 20-30g Cinnamon bark, and 50-60g Tangerine peel; blending excipients 100-150ml edible vinegar and 80-100g honey; and solvent purified water, the amount of which is to be made up to 1000ml.

[0030] The vinegar is aged vinegar, and the honey is acacia honey.

[0031] Based on the dosage range of 100-150ml of edible vinegar and 80-100g of honey in the traditional Chinese medicine formula, the ratio of edible vinegar to honey is 1:(0.8-1), which can achieve the dual effect of flavor harmony and mild medicinal properties.

[0032] The preparation process of a traditional Chinese medicine formula for weight loss includes the following steps:

[0033] Raw material pretreatment: Screen and remove impurities and non-medicinal parts from the Albizia bark, Lycium bark, Mulberry bark, Peony bark, Cinnamon bark, and Dried tangerine peel; wash and pulverize to 20-40 mesh coarse powder; let the edible vinegar stand for 24 hours to remove sediment; melt the honey in a 50℃ water bath and filter to remove impurities.

[0034] Double extraction: Put the crude powder of the Chinese medicinal materials into the extraction tank, add 8 times the amount of purified water and soak for 30 minutes. After boiling, extract by simmering for 1.5 hours and collect the first extract. Add 6 times the amount of purified water to the residue and extract by simmering again for 1 hour. Collect the second extract and combine them. Mix the residue with 4 times the amount of edible vinegar and extract at a constant temperature of 50-60℃ for 1 hour. Collect the vinegar extract.

[0035] Refining filtration: Combine the extract and the acetic acid extract, coarsely filter through a 200-mesh filter cloth, centrifuge at 3000 r / min for 15 minutes, and then finely filter through a 0.45 μm microporous membrane;

[0036] Concentration and blending: Concentrate the filtrate to 500-600ml at 60-70℃ and vacuum degree -0.08MPa. After cooling to below 40℃, add the remaining edible vinegar and processed honey, stir well, and add purified water to make up to 1000ml. Adjust the pH value to 4.0-5.0.

[0037] Sterilization and filling: Sterilize the mixed preparation by keeping it at 70-80℃ for 30 minutes, and then fill and seal it under aseptic conditions after cooling.

[0038] The edible vinegar used for extraction in step 2 accounts for 60% of the total amount of edible vinegar used, and the edible vinegar added in step 4 accounts for 40% of the total amount of edible vinegar used.

[0039] The preparation process also includes a quality control step: the finished product is a clear brown liquid, with a total saponin content of not less than 0.5g per 20ml, a total bacterial count of ≤100cfu / ml, mold and yeast counts of ≤10cfu / ml, and no pathogenic bacteria detected.

[0040] The weight loss and slimming traditional Chinese medicine preparation prepared by the preparation process is in liquid dosage form. The traditional Chinese medicine preparation has the effects of promoting fat decomposition, prolonging gastric emptying time and producing a feeling of fullness.

[0041] The traditional Chinese medicine preparation is to be taken twice a day, 20ml each time.

[0042] The application of traditional Chinese medicine formulas in the preparation of weight loss products, which are presented in liquid dosage form, achieves a dual-dimensional weight loss effect of "reducing intake" and "promoting metabolism" by synergistically promoting fat decomposition with core active ingredients, optimizing metabolism with auxiliary regulatory ingredients, and prolonging gastric emptying time with excipients. Moreover, the weight loss products are mild in nature and suitable for long-term use by people of all constitutions.

[0043] The application of traditional Chinese medicine preparations in regulating glucose and lipid metabolism and reducing food intake involves the synergistic regulation of glucose and lipid metabolism by betaine from Lycium chinense root bark, saponins from Albizia julibrissin bark, and flavonoids from Morus alba root bark, which inhibits the activity of lipase. At the same time, the volatile oil of Citrus reticulata peel and the acidic components of edible acetic acid work together to prolong gastric emptying time, thereby reducing food intake. The traditional Chinese medicine preparations mentioned in this application will not damage the spleen and stomach function of the human body.

[0044] This invention discloses a traditional Chinese medicine formula for weight loss and its application. The technical solution of this invention is described in detail below, combining specific embodiments, traditional Chinese medicine theory, and modern pharmacological research, so that those skilled in the art can clearly understand and implement this invention. This invention designs a formula based on a 1000ml finished preparation, with each component working synergistically to achieve a safe and effective weight loss effect. Specific details are as follows.

[0045] Detailed Explanation of Raw Material System:

[0046] Raw material composition and functions:

[0047] The traditional Chinese medicine formula of this invention consists of core active ingredients, auxiliary regulatory ingredients, blending excipients, and solvents. Each component has a clearly defined dosage and complementary functions, working together to achieve the dual goals of "weight loss + conditioning." The core active ingredients are 80-100g of Albizia julibrissin bark, 100-120g of Lycium chinense root bark, and 60-80g of Morus alba root bark; the auxiliary regulatory ingredients are 40-50g of Paeonia suffruticosa root bark, 20-30g of Cinnamomum cassia bark, and 50-60g of Citrus reticulata peel; the blending excipients are 100-150ml of edible vinegar (preferably aged vinegar) and 80-100g of honey (preferably Sophora japonica honey); the solvent is purified water, with the dosage adjusted to a total of 1000ml.

[0048] The core functions of Albizia julibrissin bark are to soothe the liver, regulate qi, relieve depression, and calm the mind. Its saponin components can directly inhibit fat synthesis and improve metabolic imbalances caused by emotional disturbances, reducing fat accumulation caused by emotional eating at its source. Lycium chinense root bark, as a core weight-loss ingredient in the formula, has the effects of clearing heat and cooling blood, and regulating glucose and lipid metabolism. Its betaine components can promote fat decomposition and, pharmacologically verified, can effectively reduce serum triglyceride levels, making it a key component for achieving weight loss. Mulberry bark primarily functions to promote diuresis and reduce swelling, clear the lungs and relieve asthma. Its flavonoid components can accelerate fluid circulation, promote the excretion of metabolic waste and excess fat, and alleviate excessive weight caused by fluid retention.

[0049] Among the auxiliary regulatory ingredients, peony bark clears heat, invigorates blood circulation, removes blood stasis, and unblocks the meridians, improving gastrointestinal microcirculation and creating a favorable environment for the absorption of core ingredients, significantly enhancing the bioavailability of effective components; cinnamon bark is warm in nature and can warm and unblock the meridians, dispel cold, and relieve pain, precisely balancing the medicinal properties of cold ingredients such as lycium bark and mulberry bark in the formula, avoiding damage to the spleen and stomach yang qi from long-term use, and improving the safety of the formula; dried tangerine peel regulates qi, strengthens the spleen, dries dampness, and resolves phlegm. Its volatile oil components can prolong gastric emptying time, help the body produce a natural feeling of fullness, reduce the intake of regular meals, and assist in weight loss from the perspective of "controlling intake".

[0050] Edible vinegar, used as a blending excipient, not only promotes the dissolution of active ingredients in medicinal materials but also adjusts the pH value of the preparation, maintaining dosage form stability. Its acidic components also help inhibit lipase activity, enhancing the weight loss effect. Honey, on the other hand, can mitigate the acidity of vinegar, improving the palatability of the preparation and preventing decreased compliance due to unpleasant taste. It also provides a small amount of beneficial sugars, preventing hypoglycemia during weight loss. Purified water, as the matrix for extraction and preparation, ensures the full dissolution of all components and maintains dosage form stability, making it an indispensable basic component in preparation.

[0051] Raw material processing methods and their purpose:

[0052] The raw material processing of this invention strictly follows the standards of the 2025 edition of the Chinese Pharmacopoeia, while optimizing the process according to the efficacy requirements of the formulation to ensure the maximization of the medicinal value of the raw materials. The specific processing methods and purposes are as follows:

[0053] Albizia bark: The raw material is first manually screened to remove impurities and residual woody core. Then, it is quickly rinsed three times with purified water to prevent loss of active ingredients. After rinsing, it is placed in a moistening machine to thoroughly moisten (moistening time is controlled at 2-3 hours, ideally until the cross-section of the material has no white core). Next, it is cut into 2-4mm wide strips using a cutting machine. Finally, it is placed in a drying oven and dried at 60℃ until the moisture content is ≤12%. The core purpose of this processing is to remove the non-medicinal woody core and impurities. By cutting the material into strips, the contact area between the raw material and the extraction solvent is increased. Testing shows that this can increase the dissolution rate of saponins by more than 30%.

[0054] Lycium chinense root bark: Take the raw medicinal material, remove the impurities and woody parts attached to the surface, wash with purified water, and then place it in a drying yard to dry naturally or put it in a drying oven at 70℃. After drying, cut it into 5-8mm segments. The woody core accounts for 20%-30% of the weight of the raw Lycium chinense root bark and has no medicinal value. Removing it can increase the content of effective ingredients by about 25%, while avoiding the woody core components from being mixed into the preparation and affecting the purity.

[0055] Mulberry bark: Take the raw medicinal material, scrape off the rough outer skin with a special scraper, ensuring 100% removal. Then wash with purified water, thoroughly moisten, and cut into 3-5mm strips, which are then dried at 65℃. The rough outer skin is rich in fibrous impurities that cannot be absorbed by the human body. Removing it can increase the extraction efficiency of flavonoids by 40%, ensuring full utilization of the effective components.

[0056] Peony bark: Take the raw material, remove impurities, and quickly rinse with purified water to prevent the loss of the active ingredient paeonol due to prolonged soaking. After rinsing, thoroughly moisten the bark and slice it into 0.5-1mm thin slices using a slicer. Place the slices in a ventilated place to dry. Slicing ensures full exposure of paeonol and more thorough contact with the extraction solvent, which has been measured to increase the extraction efficiency by 35%.

[0057] Cinnamon: Take the raw material, remove impurities and moldy parts, quickly wash with purified water, and then place it in a cool, ventilated place to air dry (air drying time 5-7 days, moisture content controlled at 10%-12%). After air drying, crush it into a coarse powder of 20-40 mesh using a crusher. The active ingredient in cinnamon is volatile oil. Crushing makes the volatile oil easier to release, and air drying avoids the destruction of volatile oil by high temperature, so the volatile oil retention rate can reach over 90%.

[0058] Dried tangerine peel: Take the raw material, remove impurities and insect-damaged parts, spray with a small amount of purified water to moisten thoroughly (moistening time 1 hour), cut into strips 3-5mm wide, and then place in a cool, ventilated place to air dry. The temperature during the air drying process should not exceed 30℃ to maximize the retention of volatile oil components in the dried tangerine peel. If drying is used, the loss rate of volatile oil can reach 40%, while the retention rate of volatile oil after air drying exceeds 85%.

[0059] Edible vinegar and honey: The edible vinegar is brewed aged vinegar, placed in a sealed container and left to stand for 24 hours to allow the sediment to settle completely. The clear supernatant is then collected for later use. The honey is melted in a 50℃ constant temperature water bath, and then filtered through a 100-mesh filter cloth to remove pollen residue and impurities. The purpose of processing both is to remove impurities, ensure the clarity of the preparation, and prevent impurities from affecting the stability and safety of the preparation.

[0060] Supported by Traditional Chinese Medicine Theory:

[0061] Holistic concept reflected in:

[0062] Traditional Chinese medicine (TCM) believes that obesity is not simply a matter of being overweight; its core pathogenesis is "abnormal metabolism of Qi, blood, and body fluids, leading to the internal retention of phlegm, dampness, and turbidity," which is an external manifestation of overall bodily dysfunction. Therefore, treatment should follow the principle of "holistic regulation and addressing both the symptoms and the root cause." The formula in this invention fully embodies the holistic concept of TCM, not only targeting the "symptoms" of fat accumulation but also deeply regulating the "root cause" of obesity, achieving a synergistic improvement in both weight loss and overall health.

[0063] From the perspective of treating the "symptoms," the core active ingredient, Lycium chinense root bark, inhibits fat synthesis by regulating glucose and lipid metabolism; Morus alba root bark promotes diuresis and reduces swelling, eliminating excess body fluids and fat; and Albizia julibrissin bark reduces fat accumulation by improving mood disorders. The three work together to directly address the problem of fat accumulation. From the perspective of regulating the "root cause," the auxiliary ingredient, Paeonia suffruticosa root bark, improves gastrointestinal microcirculation, ensuring smooth flow of Qi and blood, and providing a favorable environment for weight loss. Cinnamomum cassia bark balances the medicinal properties of the formula, avoiding damage to the spleen and stomach from cold ingredients, and maintaining normal spleen and stomach function. Citrus reticulata peel regulates Qi and strengthens the spleen, enhancing the spleen and stomach's ability to transport and transform water and dampness, reducing the generation of phlegm and dampness from the root.

[0064] The blending ingredients, vinegar and honey, are both food and medicine ingredients, which not only exert their medicinal value but also enhance the safety of the preparation. This makes the overall medicinal properties of the formula mild and without any adverse effects, in line with the traditional Chinese medicine concept of "preventive treatment." It helps maintain the body's yin-yang balance while losing weight, avoiding problems such as rebound weight gain and damage to the body after weight loss.

[0065] Application of syndrome differentiation and treatment:

[0066] This invention's formula, based on Traditional Chinese Medicine (TCM) diagnosis, primarily targets obesity of the "phlegm-dampness obstruction and qi stagnation and blood stasis" type, a common clinical condition. This type of obesity accounts for over 60% of the total obese population. Common symptoms include overweight, heaviness in the limbs, abdominal distension and loose stools, and depression. The tongue appearance is pale with a white, greasy coating, and the pulse is slippery. The formula precisely targets the pathogenesis to achieve syndrome differentiation and treatment, as detailed below:

[0067] For the pathogenesis of "phlegm-dampness obstruction," mulberry bark promotes diuresis and reduces swelling, directly expelling excess phlegm and dampness from the body. Tangerine peel dries dampness and resolves phlegm, reducing phlegm-dampness production. The synergistic effect of the two has been observed in clinical practice, alleviating symptoms of limb heaviness, abdominal distension, and loose stools in more than 80% of people with this syndrome. For the pathogenesis of "qi stagnation and blood stasis," albizia bark soothes the liver and regulates qi, relieving qi stagnation caused by emotional depression. Moutan bark invigorates blood and removes blood stasis, improving qi and blood circulation and preventing further deposition of turbid fat in the body, thus helping to improve emotional eating problems. For the "spleen and stomach weakness" syndrome often accompanied by this type of person, cinnamon warms the spleen and stomach, while honey tonifies the middle jiao and replenishes qi. Together, they protect the spleen and stomach function, addressing problems such as loss of appetite and fatigue that may occur during weight loss, which aligns with the TCM principle of "strengthening the body's resistance and eliminating pathogenic factors."

[0068] Meanwhile, the formula of this invention has good universality and can be fine-tuned according to different constitutions, reflecting the flexibility of TCM syndrome differentiation and treatment. For example, people with Yin deficiency (common symptoms include dry mouth and throat, hot palms and soles) can increase the amount of Lycium chinense root bark by 10%-15% on the original formula to utilize its heat-clearing and Yin-nourishing effects to suit their constitution; people with Yang deficiency (common symptoms include aversion to cold, cold limbs) can appropriately increase the amount of Cinnamomum cassia bark by 5%-10% to enhance the warming effect and make the formula more suitable for individual needs.

[0069] Modern pharmacological analysis:

[0070] Pharmacological effects of core components:

[0071] The weight-loss efficacy of the formula in this invention has been fully confirmed by modern pharmacological research. Each core component exerts its weight-loss effect through a clearly defined mechanism of action, and there is a synergistic effect among the components, as detailed below:

[0072] Lycium chinense root bark: The main active ingredients are betaine and lycium chinense root extract, which work synergistically in the weight loss process. Betaine specifically inhibits the activity of fat synthase (FAS), a key enzyme in fatty acid synthesis; reducing its activity directly reduces the amount of fatty acids synthesized. Lycium chinense root extract activates AMP-activated protein kinase (AMPK). Once activated, AMPK promotes the breakdown of fat in adipocytes into fatty acids, which are further converted into acetyl-CoA and enter the tricarboxylic acid cycle for energy, thereby reducing the amount of fat accumulated in the body. In vitro experiments have shown that Lycium chinense root bark extract can reduce the activity of fat synthase by 45% and increase the activity of AMPK by 60%.

[0073] Albizia bark: The core active ingredient is albizia bark saponins, whose mechanism of action mainly involves two aspects. First, it reduces hunger by inhibiting the secretion of orexin, an important hormone regulating hunger. Albizia bark saponins can reduce orexin secretion by 30%. Second, it improves insulin resistance, enhances insulin sensitivity, and reduces the conversion of glycogen into fat. After insulin sensitivity is improved, the body's utilization efficiency of glucose increases, and the pathway of conversion of glycogen into fat after glycogen storage is inhibited. Experiments have verified that albizia bark extract can increase insulin sensitivity by 25%.

[0074] Mulberry bark: The main active ingredient is mulberry bark flavonoids, which can increase urine output by inhibiting the reabsorption of water and sodium in the renal tubules, promoting the excretion of excess body fluids and metabolic waste, and inhibiting the proliferation of adipocytes. Adipocyte proliferation is an important factor in the aggravation of obesity. Mulberry bark flavonoids can reduce the differentiation rate of preadipocytes into mature adipocytes by 50%, thereby reducing the number of adipocytes.

[0075] To quantify the synergistic effect of the core components, a synergy coefficient (S) is introduced for evaluation. The formula for calculating the synergy coefficient is as follows: Where A represents the weight loss effect of the combined action of Lycium chinense root bark and Albizia julibrissin bark, B represents the weight loss effect of the combined action of Lycium chinense root bark and Morus alba root bark, and AB represents the weight loss effect of the combined action of all three. When S>1, it indicates that there is a synergistic effect among the components. Experimental measurements showed that A = 3.2 kg / month, B = 2.8 kg / month, and AB = 7.5 kg / month. Substituting these values ​​into the formula, the weight loss was calculated as follows: S>1 confirms that the three components have a significant synergistic effect, and the weight loss effect is better than that of a single component or a combination of two components.

[0076] Pharmacological effects of excipients and auxiliary ingredients:

[0077] Although auxiliary regulatory ingredients and blending excipients do not directly play a major role in weight loss, they can assist in weight loss by improving the absorption efficiency of active ingredients and enhancing the safety of the formulation. Their specific pharmacological effects are as follows:

[0078] Peony bark: The core active ingredient is paeonol, which can dilate gastrointestinal blood vessels, improve gastrointestinal microcirculation, and increase the absorption area of ​​drug components on the gastrointestinal mucosa. Experimental results show that after adding peony bark, the absorption efficiency of betaine in lycium bark increased from 40% to 65%, significantly improving the bioavailability of the core ingredient.

[0079] Cinnamon: The main active ingredient is cinnamaldehyde, which has a warming pharmacological effect. It can inhibit excessive contraction of gastrointestinal smooth muscle and protect the gastric mucosal barrier function. Cold ingredients such as Lycium chinense root bark and mulberry bark can easily cause gastric mucosal damage. After adding cinnamon, the incidence of gastric mucosal damage decreased from 35% to 5%. At the same time, cinnamaldehyde can promote the secretion of digestive juices and improve the digestive function of the spleen and stomach.

[0080] Dried tangerine peel: Its core active ingredients are hesperidin and volatile oils. The volatile oils can prolong gastric emptying time, which increases the duration of satiety. Tests have shown that this can extend the duration of satiety from 2 hours to 4 hours, thereby reducing the intake of snacks and main meals. Hesperidin can regulate intestinal flora, increase the number of beneficial bacteria, improve the intestinal environment, and enhance the body's metabolic capacity.

[0081] Edible vinegar: Its main component is acetic acid. Acetic acid can lower the pH value of the extraction system, causing the effective components such as alkaloids and saponins in traditional Chinese medicine to change from a bound state to a free state, thereby increasing the dissolution rate. At the same time, acetic acid can inhibit the activity of lipase, a key enzyme in the fat digestion process. Reducing its activity can decrease the digestion and absorption of fat in food, and measurements have shown that it can reduce the fat digestibility and absorption rate by 15%.

[0082] Honey: Its main components are glucose and fructose, both of which can quickly replenish energy and prevent hypoglycemia caused by insufficient energy supply during weight loss. At the same time, the polysaccharides in honey can alleviate the irritation of acetic acid on the gastric mucosa. Experiments have verified that after adding honey, the irritation index of the preparation on the gastric mucosa decreased from 8.2 to 3.1 (the lower the irritation index, the less irritating), significantly improving the tolerability of the preparation.

[0083] Specific implementation methods and data verification:

[0084] Example 1: Preparation of Standard Formulation:

[0085] Prepare 1000ml of the finished formulation according to the following steps:

[0086] Step 1: Raw material preparation. Weigh the raw materials prepared by the above method according to the following amounts: 90g of Albizia bark, 110g of Lycium bark, 70g of Mulberry bark, 45g of Peony bark, 25g of Cinnamon bark, 55g of Dried tangerine peel, 120ml of aged vinegar, 90g of Sophora honey, and appropriate amount of purified water.

[0087] Step 2: Double extraction. Place the Chinese medicinal materials into a multi-functional extraction tank, add 8 times the amount of purified water (i.e., (90+110+70+45+25+55)×8=395×8=3160ml), soak for 30 minutes, then heat to boiling and maintain a gentle boil for 1.5 hours. Collect the first extract. Add 6 times the amount of purified water (395×6=2370ml) to the residue, and extract again at a gentle boil for 1 hour. Collect the second extract and combine them to obtain approximately 4500ml of combined extract. Place the residue into the extraction tank, add 4 times the amount of aged vinegar (120×60%=72ml), heat to 55℃ and extract at a constant temperature for 1 hour. Collect approximately 60ml of vinegar extract.

[0088] Step 3: Refining filtration. Mix the combined extract with the vinegar extract, first coarsely filter with a 200-mesh filter cloth to remove the residue particles, then send it to a high-speed centrifuge and centrifuge at 3000 r / min for 15 minutes to remove fine suspended particles. Finally, finely filter through a 0.45μm microporous membrane to obtain approximately 4200ml of refined filtrate.

[0089] Step 4: Concentration and blending. The filtrate is sent to a vacuum concentration tank and concentrated to 550ml at 65℃ and a vacuum of -0.08MPa. Then, the temperature is lowered to below 40℃. The remaining aged vinegar (120-72=48ml) and the melted and filtered acacia honey are added. After stirring evenly, purified water is added to make up to 1000ml. The pH value is adjusted to 4.5.

[0090] Step 5: Sterilization and filling. The prepared formulation is pasteurized at 75°C for 30 minutes. After sterilization, it is rapidly cooled to room temperature and filled into 20ml sterile glass bottles under aseptic conditions. The bottles are then sealed to obtain the finished product.

[0091] Example 2: Preparation of a Body Constitution Micro-adjustment Formula (Suitable for Yin Deficiency Constitution):

[0092] For people with Yin deficiency constitution, the dosage of Lycium chinense root bark was adjusted to 125g (an increase of 13.6%) based on Example 1. The dosage of other raw materials and the preparation process were the same as in Example 1. A finished preparation suitable for Yin deficiency constitution was prepared. This preparation retains the weight loss effect while enhancing the heat-clearing and Yin-nourishing effects, and avoids the dry mouth symptoms that occur after taking it by people with Yin deficiency constitution.

[0093] Data validation experiment:

[0094] To verify the weight loss effect and safety of the formula of this invention, 120 obese volunteers with the "phlegm-dampness obstruction, qi stagnation and blood stasis" type (aged 25-45, BMI ≥ 28 kg / m²) were selected. 2 BMI is calculated using the formula for weight and height. Volunteers were randomly divided into three groups: an experimental group (taking the preparation of Example 1 of this invention), a control group 1 (taking the preparation without the core ingredient Lycium chinense root bark), and a control group 2 (taking commercially available chemical weight-loss capsules). Each group consisted of 40 participants. The experimental period was 30 days. During the experiment, the volunteers in each group maintained the same diet and exercise habits. Specific experimental data are as follows:

[0095] Weight loss data: The experimental group's average weight decreased from 82.5 kg to 77.2 kg, an average weight loss of 5.3 kg, and their BMI decreased from 29.8 kg / m². 2 Reduced to 27.9 kg / m 2 In control group 1, the average weight decreased from 81.8 kg to 79.5 kg, a decrease of 2.3 kg, and the BMI decreased from 29.6 kg / m². 2 Reduced to 28.8 kg / m 2 In control group 2, the average weight decreased from 83.2 kg to 78.5 kg, an average weight loss of 4.7 kg, and the BMI decreased from 30.1 kg / m². 2 Reduced to 28.4 kg / m 2 The weight loss effect of the experimental group was significantly better than that of the control group 1. The weight loss effect was similar to that of the control group 2, but the body fat percentage of the experimental group decreased more significantly. The body fat percentage of the experimental group decreased by an average of 3.2%, while that of the control group 2 decreased by an average of 1.8%, which confirms that the formula of this invention is more effective in reducing fat.

[0096] Satiety data: The visual analog scale (VAS score, 0-10, higher scores indicate stronger satiety) was used to assess the satiety of volunteers in each group after medication. The experimental group had a VAS score of 7.8 at 2 hours and 5.2 at 4 hours after medication; control group 1 had a VAS score of 4.3 at 2 hours and 2.1 at 4 hours; and control group 2 had a VAS score of 3.5 at 2 hours and 1.8 at 4 hours. The duration and intensity of satiety in the experimental group were significantly better than those in the two control groups, confirming that the synergistic effect of tangerine peel and vinegar in the formula can effectively enhance satiety.

[0097] Safety data: Adverse reactions were recorded for each group of volunteers during the experiment. In the experimental group, only 2 volunteers experienced mild stomach discomfort (adverse reaction rate 5%), and the symptoms resolved spontaneously. In control group 1, 3 volunteers experienced stomach discomfort (adverse reaction rate 7.5%). In control group 2, 12 volunteers experienced stomach discomfort, 6 experienced diarrhea, and 4 experienced insomnia (adverse reaction rate 55%). The incidence of adverse reactions in the experimental group was significantly lower than that in control group 2, confirming that the formulation of this invention is mild and has higher safety.

[0098] Biochemical data: Serum triglyceride (TG) and total cholesterol (TC) levels were measured in each group of volunteers before and after the experiment. In the experimental group, serum TG decreased from 2.8 mmol / L to 1.9 mmol / L, and TC decreased from 5.6 mmol / L to 4.5 mmol / L. In control group 1, serum TG decreased from 2.7 mmol / L to 2.4 mmol / L, and TC decreased from 5.5 mmol / L to 5.1 mmol / L. In control group 2, serum TG decreased from 2.9 mmol / L to 2.1 mmol / L, and TC decreased from 5.7 mmol / L to 4.8 mmol / L. The improvement in biochemical indicators in the experimental group was better than that in control group 1 and close to that in control group 2, confirming that the formula of this invention can effectively regulate glucose and lipid metabolism.

[0099] Instructions for use and precautions:

[0100] Dosage instructions:

[0101] The recommended dosage of this invention is 20ml twice daily, 30 minutes before breakfast and 30 minutes before dinner, respectively. It can be taken directly without dilution. Taking it before breakfast can suppress appetite in the morning, reducing the amount consumed at breakfast and lunch; taking it before dinner can prolong the feeling of fullness at night, preventing late-night snacking. Furthermore, nighttime is the active period for fat synthesis, so taking it at this time can better exert its inhibitory effect on fat synthesis.

[0102] Beneficial effects:

[0103] The present invention discloses a traditional Chinese medicine formula for weight loss and its application. Compared with existing weight loss technologies and products, it achieves multi-dimensional technological breakthroughs and improved effects through scientific formula design, precise processing technology, reasonable preparation process and clear mechanism of action. Its beneficial effects are specifically reflected in multiple aspects such as weight loss mechanism, safety performance, dosage form application, traditional Chinese medicine conditioning and industrialization value. Moreover, the effects support each other and synergistically enhance each other, forming a complete technical system that combines scientificity and practicality.

[0104] Firstly, regarding the weight loss mechanism, this invention breaks through the limitations of traditional weight loss products that rely on a single weight loss path. It constructs a dual-dimensional synergistic weight loss system of "reduced intake + promoted metabolism," achieving both high efficiency and sustainability in weight loss. Traditional Chinese medicine for weight loss often relies solely on the metabolic regulation of a single ingredient or achieves short-term weight loss simply by suppressing appetite, which easily leads to problems such as fluctuating effects and incomplete weight loss. In contrast, this invention, through the precise ratio of core active ingredients and auxiliary regulatory ingredients, enables the weight loss effect to work simultaneously on multiple targets. From the perspective of promoting metabolism, the betaine component in Lycium chinense root bark can specifically inhibit the activity of lipase and reduce the amount of fatty acid synthesis. Lycium chinense root bark extract can activate AMP-activated protein kinase, promote the breakdown of fat in adipocytes into fatty acids and participate in energy metabolism. Albizia julibrissin in Albizia julibrissin bark can improve insulin resistance, enhance insulin sensitivity, and reduce the conversion of glycogen into fat. Morus alba root bark flavonoids can inhibit the proliferation of adipocytes and reduce the number of adipocytes. These four core components work synergistically to construct a complete metabolic promotion network from four levels: inhibition of fat synthesis, promotion of fat breakdown, regulation of metabolic pathways, and inhibition of adipocyte proliferation. From the perspective of reducing intake, the volatile oil components in dried tangerine peel and the acidic components in edible vinegar can jointly stimulate the gastrointestinal mucosa, prolong gastric emptying time, and produce a natural and lasting feeling of fullness. At the same time, albizia bark saponins can inhibit the secretion of orexin, reducing the transmission of hunger signals, while the sweet components in honey can alleviate the discomfort caused by hunger, preventing overeating caused by excessive hunger. This triple food control mechanism of "physiological satiety + signal inhibition + physical relief" effectively solves the core pain points of "easy hunger and difficulty in sticking to the diet" during weight loss. Data verification shows that the experimental group using the technical solution of this invention lost an average of 5.3 kg and decreased body fat percentage by 3.2% within a 30-day experimental period. The weight loss effect was not only significantly better than the control group 1 without the core ingredients, but the decrease in body fat percentage was also far greater than that of the control group 2 using commercially available chemical weight loss capsules. This confirms the high efficiency of this dual-dimensional weight loss mechanism, while also avoiding problems such as muscle loss that may be caused by simple weight loss, thus achieving the goal of healthy weight loss.

[0105] Secondly, regarding safety, this invention fully embodies the concept of "medicine and food from the same source, gentle weight loss," completely solving the safety issues of traditional weight loss products and providing a guarantee for long-term use by people of all constitutions. Chemical weight loss products often contain ingredients such as orlistat, which can easily cause adverse reactions such as gastrointestinal discomfort, liver and kidney damage, and insomnia. In the experiment, the incidence of adverse reactions in control group 2 was as high as 55%. Traditional Chinese medicine weight loss formulas also often cause problems such as spleen and stomach damage and physical imbalance due to excessively strong medicinal properties. This invention constructs a comprehensive safety assurance system from three levels: formula design, excipient selection, and process optimization. In terms of formula design, it follows the traditional Chinese medicine theory of "balance between cold and heat." The core active ingredients, such as Lycium chinense root bark and mulberry bark, are both cold in nature and easily damage the spleen and stomach's yang energy. Therefore, it is specially combined with cinnamon bark, which is warm in nature. The cinnamaldehyde in cinnamon bark warms the meridians, warms the spleen and stomach, and balances the overall medicinal properties of the formula. At the same time, dried tangerine peel regulates qi and strengthens the spleen, while honey replenishes qi and strengthens the spleen and stomach, further enhancing the protective effect and avoiding problems such as loss of appetite and fatigue caused by long-term use. In terms of excipient selection, both edible vinegar and honey are medicinal and edible ingredients. The ingredients, derived from the same source, not only possess medicinal value but also exhibit extremely high safety. Edible vinegar promotes the dissolution of active ingredients, while honey mitigates the acidity and irritation of vinegar. Their synergistic effect enhances the efficacy and palatability of the preparation while avoiding the risks associated with chemical additives. In terms of process optimization, all raw materials are processed strictly according to the standards of the Chinese Pharmacopoeia. By removing impurities and precisely controlling parameters such as temperature and humidity, the effective components are preserved to the maximum extent while harmful impurities are removed. The preparation process employs gentle processes such as low-temperature concentration and pasteurization to avoid the generation of toxic or harmful substances from high-temperature or chemical treatments. Experimental verification shows that the adverse reaction rate in the experimental group of this invention is only 5%, and only mild stomach discomfort, with symptoms that can be relieved spontaneously. Its safety is far superior to commercially available chemical weight-loss products and also better than traditional Chinese medicine formulas. Even for individuals with special constitutions such as excessive stomach acid, yin deficiency, or yang deficiency, the formula can be adapted by slightly adjusting the dosage. For example, individuals with yin deficiency can increase the dosage of Lycium chinense root bark by 10%-15%, and individuals with yang deficiency can increase the dosage of cinnamon bark by 5%-10%, further enhancing the universality and safety of the formula.

[0106] Third, regarding dosage form application, this invention selects a liquid dosage form and optimizes the preparation process, giving the formulation significant advantages of "rapid absorption, convenient administration, and high compliance," thus overcoming the limitations of traditional Chinese medicine dosage forms. Traditional Chinese medicine weight loss products are mostly available in the form of pills, tablets, and decoctions. Pills and tablets have slow dissolution of active ingredients, low absorption efficiency in the human body, and long onset of action, while decoctions have problems such as inconvenience of administration, difficulty in controlling dosage, and easy deterioration, all of which lead to poor user compliance. This invention employs a liquid dosage form, combining a dual extraction process of "water decoction + vinegar extraction" with a multi-step refining and filtration process to maximize the dissolution and absorption efficiency of the active ingredients. In the dual extraction process, water decoction fully dissolves water-soluble components in the medicinal materials, such as betaine in Lycium chinense root bark and saponins in Albizia julibrissin bark, while vinegar extraction specifically dissolves fat-soluble components, such as paeonol in Paeonia suffruticosa root bark. The combination of these two extraction methods achieves comprehensive extraction of the active ingredients, preventing component loss. The refining and filtration process involves coarse filtration through a 200-mesh filter cloth, centrifugation at 3000 r / min, and microfiltration at 0.45 μm. The three-step fine filtration process using a porous membrane removes medicinal residues, suspended particles, and other impurities, ensuring that the active ingredients are evenly dispersed in the formulation in small molecule form. This significantly improves the absorption efficiency of the human small intestine. The absorption rate of the liquid dosage form is 3-5 times faster than that of the solid dosage form, resulting in a more rapid onset of action. Furthermore, the liquid dosage form, after sterilization and filling, can be taken directly orally without the need for complicated operations such as brewing or decocting. Each 20ml bottle precisely corresponds to a single dose, making it convenient and quick to take. It is suitable for various scenarios such as home, office, and travel, significantly improving user compliance and providing convenient conditions for long-term weight loss.

[0107] Fourth, in terms of TCM conditioning, this invention deeply integrates the holistic concept and syndrome differentiation of TCM, achieving the goal of "simultaneous weight loss and conditioning," completely differentiating itself from traditional weight loss products that only focus on changes in weight numbers. TCM believes that obesity is essentially caused by "abnormal metabolism of Qi, blood, and body fluids, and internal retention of phlegm, dampness, and turbidity," an external manifestation of overall bodily dysfunction. Therefore, weight loss should not only treat the symptoms but also address the root cause. This invention's formula precisely targets the most common clinical type of obesity: "internal obstruction of phlegm and dampness, and stagnation of Qi and blood." The formula is designed from the perspective of "treating both the symptoms and the root cause": For the symptom of "internal obstruction of phlegm and dampness," mulberry bark promotes diuresis and reduces swelling, directly expelling excess phlegm and dampness from the body; tangerine peel dries dampness and resolves phlegm, reducing phlegm and dampness formation. For the pathogenesis of "stagnation of Qi and blood," albizia bark soothes the liver, regulates Qi, and relieves Qi stagnation caused by emotional depression; peony bark invigorates blood and removes blood stasis, improving Qi and blood circulation and preventing further deposition of turbidity. For the root cause of "weak spleen and stomach," cinnamon bark, tangerine peel, and honey work synergistically to strengthen the spleen and stomach's digestive function, reducing phlegm and dampness formation from the root. This approach, combining symptom treatment with overall conditioning, not only achieves weight loss but also alleviates common symptoms in obese individuals such as limb heaviness, abdominal distension, loose stools, and depression. Clinical observations show that over 80% of people with this condition experience symptom relief after taking the product. Furthermore, the formula of this invention offers excellent flexibility, allowing for adjustments based on individual constitutions. For example, for those with Yin deficiency, increasing the dosage of Lycium bark enhances its heat-clearing and Yin-nourishing effects; for those with Yang deficiency, increasing the dosage of Cinnamon bark strengthens its warming effect. This fully embodies the individualized advantages of traditional Chinese medicine's syndrome differentiation and treatment, achieving the goal of "weight loss without harming the body, and healthier slimming," aligning with modern health concepts.

[0108] Fifth, in terms of industrialization value, the technical solution of this invention has significant advantages such as "easy availability of raw materials, mature technology, controllable cost, and great market potential," providing a solid foundation for large-scale production and widespread application. The weight loss market has huge demand, but existing products fail to meet consumer needs due to insufficient safety, poor efficacy, or excessive cost. The medicinal materials used in this invention, such as Albizia julibrissin bark, Lycium chinense root bark, Morus alba root bark, Paeonia suffruticosa root bark, Cinnamomum cassia bark, and Citrus reticulata peel, are all commonly available medicinal materials in the market, with a stable supply chain and affordable prices. Edible vinegar and honey are also mass-market consumer products, making raw material costs controllable. According to calculations, the raw material cost per 1000ml of finished preparation is only 80-100 yuan, making the final price competitive in the market. The equipment involved in the preparation process, such as multi-functional extraction tanks, vacuum concentration tanks, and high-speed centrifuges, are all mature equipment in the field of traditional Chinese medicine preparations, requiring no special customization. Production enterprises can quickly realize equipment investment and capacity expansion. At the same time, the process steps are clear, and the parameters are well-defined, such as extraction temperature controlled at 50-70℃, centrifugation speed at 3000r / min, and sterilization temperature at 70-80℃, which facilitates standardized production and ensures stable product quality. The finished preparation has a shelf life of up to 12 months, making it easy to store and transport, and suitable for nationwide market promotion. Furthermore, the technical solution of this invention can not only be applied to weight loss products, but also to the fields of sub-health conditioning and metabolic syndrome improvement, as well as the regulation of sugar and lipid metabolism and the improvement of gastrointestinal function. This further expands the scope of market application and has extremely high industrialization value and market potential.

[0109] Finally, in terms of technological innovation and advancement, this invention constructs a three-in-one innovative system of "formula-process-efficacy," possessing outstanding substantive characteristics and significant progress. Regarding formula innovation, it is the first to use Albizia bark and Lycium bark as core active ingredients, combined with specific proportions of Mulberry bark, Peony bark, Cinnamon bark, and Dried tangerine peel, along with edible vinegar and honey to form a compound formula. This formula combination is not found in existing technologies and possesses novelty. In terms of process innovation, the dual extraction process of "water decoction + vinegar extraction" achieves comprehensive dissolution of both water-soluble and fat-soluble components. Multi-step refining filtration and gentle sterilization processes ensure the purity and stability of the preparation, and the process design is scientifically sound. Regarding efficacy innovation, the satiety design is integrated into the formula system, achieving a synergistic effect of "weight loss + food control," solving key technical problems in the weight loss field while also considering safety and conditioning effects. Its technical level far surpasses existing similar products. This comprehensive innovation ensures that the technical solution of this invention not only possesses the novelty, inventiveness, and practicality required for patent authorization but also provides a safe, efficient, and healthy new solution for the weight loss product market, promoting the development and progress of traditional Chinese medicine weight loss technology.

[0110] The present invention and its embodiments have been described above. This description is not restrictive, and the accompanying drawings are only one embodiment of the present invention; the actual structure is not limited thereto. In conclusion, if those skilled in the art are inspired by this description and design similar structures and embodiments without departing from the spirit of the invention, such designs should fall within the protection scope of the present invention.

Claims

1. A slimming traditional Chinese medicine formula, characterized in that: the formula comprises the following components by weight or volume, based on 1000 ml of the finished product: core active ingredients 80-100 g Albizia julibrissin, 100-120 g Colla Corii Asini, 60-80 g White Mulberry Root-Bark; auxiliary regulating ingredients 40-50 g Cortex Moutan, 20-30 g Cinnamomum Cassia, 50-60 g Citrus Peel; blending adjuvants 100-150 ml edible vinegar, 80-100 g honey; and solvent purified water, the amount of which is made up to 1000 ml. 2.The slimming traditional Chinese medicine formula of claim 1, characterized in that: the edible vinegar is aged vinegar, and the honey is Sophora honey. 3.The slimming traditional Chinese medicine formula of claim 1, characterized in that: based on the amount of 100-150 ml edible vinegar and 80-100 g honey in the formula, the amount ratio of the edible vinegar to the honey is 1:(0.8-1), which achieves the dual effects of flavor coordination and medicinal property moderation. 4.A preparation process of the slimming traditional Chinese medicine formula of any one of claims 1-3, characterized in that: the process comprises the following steps: raw material pretreatment: screening and removing impurities and non-medicinal parts from the Albizia julibrissin, Colla Corii Asini, White Mulberry Root-Bark, Cortex Moutan, Cinnamomum Cassia, and Citrus Peel, and then washing and crushing to 20-40 mesh coarse powder; standing the edible vinegar for 24 hours to remove the precipitate, and then filtering the melted honey at 50℃ to remove impurities; double extraction: putting the coarse powder of the traditional Chinese medicinal materials into an extraction tank, adding 8 times the amount of purified water to soak for 30 minutes, boiling and then extracting at a low boil for 1.5 hours to collect the first extraction liquid; adding 6 times the amount of purified water to the residue, and then extracting at a low boil for 1 hour to collect the second extraction liquid and combine; mixing the residue with 4 times the amount of edible vinegar, and then extracting at a constant temperature of 50-60℃ for 1 hour to collect the vinegar extraction liquid; refining and filtering: combining the extraction liquid and the vinegar extraction liquid, coarsely filtering through 200 mesh filter cloth, centrifuging at 3000 r / min for 15 minutes, and then fine filtering through a 0.45 μm microporous filter membrane; concentration and blending: concentrating the fine filtrate to 500-600 ml under the conditions of 60-70℃ and a vacuum degree of-0.08 MPa, and then adding the remaining edible vinegar and treated honey after cooling to below 40℃, stirring uniformly, and adding purified water to make up to 1000 ml, and adjusting the pH value to 4.0-5.0; sterilization and filling: sterilizing the blended preparation at 70-80℃ for 30 minutes, and then filling and sealing in a sterile environment after cooling. 5.The preparation process of the slimming traditional Chinese medicine formula of claim 4, characterized in that: the edible vinegar used for extraction in step 2 accounts for 60% of the total amount of edible vinegar, and the edible vinegar added in step 4 accounts for 40% of the total amount of edible vinegar. 6.The preparation process of the slimming traditional Chinese medicine formula of claim 4, characterized in that: ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ The preparation process also comprises a quality control step: the finished product is a brownish clear liquid, the total saponin content is not less than 0.5 g per 100 ml, the total number of colonies is ≤100 cfu / ml, the number of molds and yeasts is ≤10 cfu / ml, and no pathogenic bacteria are detected.

7. A weight loss and slimming traditional Chinese medicine preparation prepared by the preparation process of any one of claims 4-6, characterized in that: The traditional Chinese medicine preparation is in liquid dosage form, and the traditional Chinese medicine preparation has the effects of promoting fat decomposition and prolonging gastric emptying time to produce satiety.

8. The weight loss and slimming traditional Chinese medicine preparation prepared by the preparation process of claim 7, characterized in that: The traditional Chinese medicine preparation is taken 2 times a day, and 20 ml is taken each time.

9. Use of the traditional Chinese medicine formula of any one of claims 1-3 in the preparation of a weight loss and slimming product, characterized in that: The weight loss and slimming product is in liquid dosage form, the weight loss and slimming product realizes the dual-dimension weight loss effect of "reducing intake" and "promoting metabolism" through the synergistic promotion of fat decomposition by the core efficacy components, the optimization of body metabolism by the auxiliary adjusting components, and the prolongation of gastric emptying time by the harmonizing auxiliary materials, and the weight loss and slimming product is mild in nature and suitable for long-term use by people of all constitutions.

10. Use of the traditional Chinese medicine preparation of claim 7 in the regulation of sugar and lipid metabolism and the reduction of food intake, characterized in that: The traditional Chinese medicine preparation synergistically regulates sugar and lipid metabolism through betaine in periploca, saponins in albizzia julibrissin, and flavonoid components in mulberry bark, and inhibits the activity of fat synthesis enzyme, while the traditional Chinese medicine preparation prolongs gastric emptying time through the combined action of volatile oil in pericarpium citri reticulatae and acidic components in edible vinegar to reduce food intake, and the traditional Chinese medicine preparation does not cause damage to the functions of the human spleen and stomach in the use.

Images