Anti-oxidation sunscreen composition and preparation method thereof

Abstract

The invention belongs to the technical field of cosmetic preparation, and particularly relates to an antioxidant sunscreen composition and a preparation method thereof. The herba portulacae extract, the gentiana veitchiorum extract and the broad-leaved epiphyllum extract serve as active components, ethyl hexyl triazinone, methylene bis-benzotriazolyl tetramethyl butyl phenol, glycerin, butanediol and other components are added, ultraviolet rays with specific wavelengths are absorbed through a molecular structure, and stimulation of the ultraviolet rays can be reduced; the raw materials such as polyglycerol-3 methyl glucose distearate, carbomer and xanthan gum are added, so that the product is prevented from layering or inactivating, and the irritation of the chemical sun-screening agent is reduced. Therefore, the sunscreen composition provided by the invention has the advantages of physical barrier reflection, chemical absorption conversion and synergistic interaction, and the composition is stable in system, good in skin feeling, high in safety, capable of efficiently resisting oxidation and remarkably blocking sunshine, and gives consideration to both broad-spectrum protection and use experience.

Description

Technical Field

[0001] This invention belongs to the field of cosmetic preparation technology, specifically relating to a sunscreen composition for anti-oxidation and its preparation method. Background Technology

[0002] Organisms produce reactive oxygen free radicals during metabolism. Although the body's antioxidant system (such as superoxide dismutase SOD and glutathione GSH) can maintain the dynamic balance of free radicals under normal physiological conditions, when the body is exposed to external stimuli such as ultraviolet radiation and environmental pollution, the body's own antioxidant system function will decline, triggering oxidative stress, which is not conducive to the body's healthy development.

[0003] Antioxidant sunscreen compositions are a research hotspot in this field. For example, Chinese patent CN 104224600 A describes an antioxidant sunscreen essential oil that combines sweet almond oil, squalene, titanium dioxide, anthocyanins, tomato extract, lavender essential oil, and chamomile essential oil through a special process. This oil can prevent melanin production and provide sun protection and antioxidant effects. Another example is CN 104606068 A, which provides an emulsion containing 0.1-20% bioactive peptides and 1-30% sunscreen agents. The bioactive peptides in this patent are dipeptides and tripeptides with antioxidant activity. The dipeptide is carnosine, and the tripeptide is selected from one or more of glutathione, synthetic tripeptide phenylalanine-lysine-leucine, and collagen tripeptide. These components protect the skin from UV radiation while eliminating free radical damage. While the aforementioned solutions can also be used for anti-oxidation and sun protection, existing products can no longer fully meet market demands due to consumers' increasing pursuit of "natural, effective, and gentle" skincare. Therefore, providing a combination that offers excellent anti-oxidation and sun protection while being gentle and non-irritating would broaden market demand in this field. Summary of the Invention

[0004] The purpose of this invention is to provide a sunscreen composition for anti-oxidation and a method for preparing the same. The composition is highly effective in anti-oxidation, has high safety, and a good skin feel, and can be used to prepare sunscreen products.

[0005] This invention provides a sunscreen composition for anti-oxidation, comprising, by weight parts, the following raw materials: Ethylhexyl triazine 2.5-3.5 parts, methylene bis-benzotriazolyl tetramethyl butylphenol 5-6 parts, glycerin 4-5 parts, butylene glycol 1-2 parts, 1,3-propanediol 0.5-1 parts, sodium hyaluronate 0.1-0.5 parts, polyglycerol-3-methyl glucoside distearate 1-3 parts, behenol 1-2 parts, decyl glucoside 1-2 parts, carbomer 0.1-0.5 parts, C10-30 alkanol acrylate crosspolymer 0.1-0.5 parts, xanthan gum 0.05-0.2 parts, diol preservative 1.5-2.5 parts, ethylhexyl glycerin 0.1-0.5 parts, vitamin E 0.1-0.5 parts, active ingredient 0.08-0.3 parts, and water 50-70 parts; The diol preservatives include: 1,2-hexanediol and 1,2-pentanediol; The active ingredients include: purslane extract, hosta extract, gentian extract, and epiphyllum extract.

[0006] Preferably, the mass ratio of purslane extract, hosta extract, gentian extract, and epiphyllum extract in the active components is 0.2-0.6:0.5-0.9:1-1.5; In the diol preservative, the mass ratio of 1,2-hexanediol to 1,2-pentanediol is 1:1-2.5.

[0007] Preferably, by weight, the following raw materials are included: 3.5 parts ethylhexyl triazine ketone, 6 parts methylene bis-benzotriazolyl tetramethyl butylphenol, 5 parts glycerin, 2 parts butanediol, 1 part 1,3-propanediol, 0.5 parts sodium hyaluronate, 3 parts polyglycerol-3-methyl glucoside distearate, 2 parts behenol, 2 parts decyl glucoside, 0.5 parts carbomer, 0.5 parts C10-30 alkanol acrylate crosspolymer, 0.2 parts xanthan gum, 2.5 parts diol preservative, 0.5 parts ethylhexyl glycerin, 0.5 parts vitamin E, 0.3 parts active ingredient, and 70 parts water; The active ingredients have a mass ratio of purslane extract, hosta extract, gentian extract, and epiphyllum extract of 0.2:0.6:1.1. In the diol preservative, the mass ratio of 1,2-hexanediol to 1,2-pentanediol is 1:1.3.

[0008] Preferably, by weight, the product comprises the following raw materials: 3 parts ethylhexyl triazine ketone, 5 parts methylene bis-benzotriazolyl tetramethyl butylphenol, 5 parts glycerin, 2 parts butanediol, 1 part 1,3-propanediol, 0.5 parts sodium hyaluronate, 3 parts polyglycerol-3-methyl glucoside distearate, 2 parts behenol, 2 parts decyl glucoside, 0.5 parts carbomer, 0.5 parts C10-30 alkanol acrylate crosspolymer, 0.2 parts xanthan gum, 2.5 parts diol preservative, 0.5 parts ethylhexyl glycerin, 0.5 parts vitamin E, 0.2 parts active ingredient, and 71.6 parts water; The active ingredients have a mass ratio of purslane extract, hosta extract, gentian extract, and epiphyllum extract of 0.2:0.6:1.1. In the diol preservative, the mass ratio of 1,2-hexanediol to 1,2-pentanediol is 1:1.3.

[0009] Preferably, the purslane extract includes: purslane aqueous extract; The preparation method of the blue hosta gentian extract is as follows: The whole plant of Gentiana scabra was mixed with acetone solution and microwaved for extraction. Solid-liquid separation, concentration and drying were then performed to obtain Gentiana scabra extract. The volume concentration of the acetone solution is 55%-65%.

[0010] Preferably, during microwave extraction, the mass-to-volume ratio of the whole plant of Gentiana scabra to the acetone solution is 1g:12-15mL; The microwave extraction power is 250-350w, the time is 20-30min, and the temperature is 48-53℃.

[0011] Preferably, the method for preparing the epiphyllum extract is as follows: Using an ethanol solution with a volume concentration of 3%-8% as an entrainer, the petals of Epiphyllum oxypetalum were extracted by supercritical CO2 extraction to obtain Epiphyllum oxypetalum residue; The residue of Epiphyllum oxypetalum was mixed and soaked with an ethanol solution with a volume concentration of 30-40%. After solid-liquid separation, activated carbon was added, and then the mixture was filtered to obtain the filtrate. After recovering ethanol from the filtrate, the solution was spray-dried to obtain the epiphyllum extract.

[0012] Preferably, the supercritical CO2 extraction is performed at a pressure of 15-25 MPa, a temperature of 40-50°C, and a time of 30-40 min.

[0013] Preferably, during the mixed soaking, the mass-to-volume ratio of the epiphyllum residue to the ethanol solution with a volume concentration of 30-40% is 1g: 5.5-7.5mL; The temperature for mixing and soaking is 25-30℃, and the time is 5-8 hours.

[0014] This invention provides a method for preparing the sunscreen composition described above, comprising the following steps: S1. Preparation of oil phase: Ethylhexyl triazine ketone, polyglycerol-3-methyl glucoside distearate and behenol are dissolved at 70-75℃ to obtain the oil phase; S2. Aqueous phase preparation: Glycerin, butanediol, 1,3-propanediol and water are mixed to obtain a first mixture; the first mixture is then mixed with carbomer at 70-75°C to obtain a second mixture. Methylenebis-benzotriazolyltetramethylbutylphenol was mixed thoroughly with 1,2-hexanediol to obtain a third mixture; the second and third mixtures were then mixed to obtain an aqueous phase. S3, Emulsification stage: After mixing the oil phase and the aqueous phase, xanthan gum, sodium hyaluronate and active components are added at 40-45℃ and stirred evenly to obtain the emulsion product; S4. Post-processing adjustment: At 35-40℃, mix the emulsion product, vitamin E, 1,2-pentanediol, decyl glucoside, C10-30 alkanol acrylate crosspolymer and ethylhexylglycerin, and adjust the pH to 5.5-6.0 to obtain the sunscreen composition.

[0015] Beneficial effects: This invention provides a sunscreen composition for anti-oxidation, comprising, by weight parts: 2.5-3.5 parts ethylhexyl triazine, 5-6 parts methylene bis-benzotriazolyl tetramethyl butylphenol, 4-5 parts glycerin, 1-2 parts butylene glycol, 0.5-1 part 1,3-propanediol, 0.1-0.5 parts sodium hyaluronate, 1-3 parts polyglycerol-3-methylglucose distearate, 1-2 parts behenol, 1-2 parts decyl glucoside, 0.1-0.5 parts carbomer, 0.1-0.5 parts C10-30 alkanol acrylate crosspolymer, 0.05-0.2 parts xanthan gum, 1.5-2.5 parts diol preservative, 0.1-0.5 parts ethylhexylglycerin, and vitamin E. 0.1-0.5 parts, 0.08-0.3 parts of active ingredient and 50-70 parts of water; the diol preservatives include 1,2-hexanediol and 1,2-pentanediol; the active ingredients include purslane extract, hosta gentian extract and epiphyllum extract.

[0016] This invention, by adding ingredients such as ethylhexyl triazine ketone, methylene bis-benzotriazolyl tetramethylbutylphenol, and vitamin E, absorbs specific wavelengths of ultraviolet light through its molecular structure, thus reducing the irritation caused by ultraviolet radiation. The addition of polyglycerol-3-methylglucose distearate, carbomer, and xanthan gum not only helps prevent product delamination or inactivation but also reduces the irritation of chemical sunscreens. Furthermore, the addition of purslane extract, gentian extract, and epiphyllum extract enhances the skin's antioxidant properties. Therefore, the sunscreen composition provided by this invention has the advantages of physical barrier reflection, chemical absorption and conversion, and synergistic effects. The system is stable, has a good skin feel, and is safe, balancing broad-spectrum protection with a pleasant user experience. Detailed Implementation

[0017] In this invention, unless otherwise specified, all raw materials and equipment used are conventionally purchased.

[0018] The sun protection factor (SPF) meter described in this invention is from Shanghai Yichi. 290AS Sun Protection Factor Tester.

[0019] The methylene bis-benzotriazolyltetramethylbutylphenol used in this invention is preferably nano-sized methylene bis-benzotriazolyltetramethylbutylphenol; the xanthan gum is preferably suspended nanoparticle xanthan gum.

[0020] To further illustrate the present invention, the solutions provided by the present invention will be described in detail below with reference to the embodiments, but they should not be construed as limiting the scope of protection of the present invention.

[0021] Example 1 The steps for preparing a sunscreen composition for antioxidant purposes are as follows: (1) Preparation of purslane extract Purslane ( Purslane The whole herb of L. was cleaned, dried and crushed to obtain the crushed material; The pulverized material was mixed with water at a mass ratio of 1:20 and cooked for 1 hour. The mixture was then filtered to obtain the filtrate. The filtrate was concentrated and dried until the mass of the substance no longer changed, thus obtaining the purslane water extract.

[0022] (2) Preparation of Gentiana scabra extract Blue jade hairpin and gentian ( Gentianaceae The whole herb (Hemsl.) was washed, dried, and crushed to obtain a powder. The pulverized material was mixed with a 55% acetone solution at a mass-to-volume ratio of 1 g: 15 mL, and microwaved at 250 W and 48 °C for 20 min to obtain a microwave extract. The microwave extract was filtered, and the filtrate was concentrated and dried until the mass of the substance no longer changed, thus obtaining the Gentiana scabra extract.

[0023] (3) Preparation of Epiphyllum extract Epiphyllum ( Epiphyllum oxypetalum (DC.) Supercritical CO2 extraction was performed on the petals of Haw. The CO2 extraction pressure was 15 MPa, the temperature was 40℃, and the time was 30 min. A 3% ethanol solution was used as an entrainer to obtain a mixture of Epiphyllum residue and ethanol. Epiphyllum residue and 30% ethanol solution were mixed at a mass-volume ratio of 1g:6mL and soaked at 30℃ for 5h. After filtration, the first filtrate was obtained. The first filtrate was mixed with activated carbon at a mass ratio of 100:0.2 and stirred for 30min. The activated carbon was then removed to obtain the second filtrate. After recovering the ethanol from the second filtrate, the extract of Epiphyllum oxypetalum was obtained by spray drying.

[0024] (4) Raw materials used in antioxidant sunscreen compositions The sunscreen composition for antioxidant purposes, by weight, comprises: 3.5 parts ethylhexyl triazine, 6 parts methylene bis-benzotriazolyl tetramethyl butylphenol, 5 parts glycerin, 2 parts butylene glycol, 1 part 1,3-propanediol, 0.5 parts sodium hyaluronate, 3 parts polyglycerol-3-methyl glucoside distearate, 2 parts behenol, 2 parts decyl glucoside, 0.5 parts carbomer, 0.5 parts C10-30 alkanol acrylate crosspolymer, 0.2 parts xanthan gum, 2.5 parts diol preservative, 0.5 parts ethylhexyl glycerin, 0.5 parts vitamin E, 0.3 parts active ingredient, and 70 parts water; The active ingredients have a mass ratio of purslane extract, hosta extract, gentian extract, and epiphyllum extract of 0.2:0.6:1.1. In the diol preservative, the mass ratio of 1,2-hexanediol to 1,2-pentanediol is 1:1.3.

[0025] (5) Preparation method of antioxidant sunscreen composition S1. Preparation of oil phase: Ethylhexyl triazine ketone, polyglycerol-3-methyl glucoside distearate and behenol were dissolved at 75°C to obtain the oil phase; S2. Aqueous phase preparation: Glycerol, butanediol, 1,3-propanediol and water are mixed to obtain a first mixture; the first mixture is then mixed with carbomer at 75°C to obtain a second mixture. Methylenebis-benzotriazolyltetramethylbutylphenol was mixed thoroughly with 1,2-hexanediol to obtain a third mixture; the second and third mixtures were then mixed to obtain an aqueous phase. S3, Emulsification stage: After mixing the oil phase and the aqueous phase, xanthan gum, sodium hyaluronate and active components are added at 40-45℃ and stirred evenly to obtain the emulsion product; S4. Post-processing adjustment: At 35-40℃, mix the emulsion product, vitamin E, 1,2-pentanediol, decyl glucoside, C10-30 alkanol acrylate crosspolymer and ethylhexylglycerin, and adjust the pH to 5.5-6.0 to obtain the sunscreen composition.

[0026] Example 2 The steps for preparing a sunscreen composition for antioxidant purposes are as follows: (1) Preparation of purslane extract Same as step (1) in Example 1; (2) Preparation of Gentiana scabra extract Clean the whole plant of Gentiana scabra, dry it, and then crush it to obtain the crushed material; The pulverized material was mixed with a 65% acetone solution at a mass-to-volume ratio of 1 g: 12 mL, and microwaved at 250 W and 48 °C for 20 min to obtain a microwave extract. The microwave extract was filtered, and the filtrate was concentrated and dried until the mass of the substance no longer changed, thus obtaining the Gentiana scabra extract.

[0027] (3) Preparation of Epiphyllum extract The petals of the Epiphyllum oxypetalum were subjected to supercritical CO2 extraction at a pressure of 15 MPa, a temperature of 40 °C, and a time of 30 min. An 8% ethanol solution was used as an entrainer to obtain a mixture of Epiphyllum oxypetalum residue and ethanol. Epiphyllum residue and 40% ethanol solution were mixed at a mass-volume ratio of 1g:6mL and soaked at 30℃ for 5h. After filtration, the first filtrate was obtained. The first filtrate was mixed with activated carbon at a mass ratio of 100:0.2 and stirred for 30min. The activated carbon was then removed to obtain the second filtrate. After recovering the ethanol from the second filtrate, the extract of Epiphyllum oxypetalum was obtained by spray drying.

[0028] (4) Raw materials used in antioxidant sunscreen compositions The sunscreen composition for antioxidant purposes, by weight, comprises: 3 parts ethylhexyl triazine, 5 parts methylene bis-benzotriazolyl tetramethyl butylphenol, 5 parts glycerin, 2 parts butylene glycol, 1 part 1,3-propanediol, 0.5 parts sodium hyaluronate, 3 parts polyglycerol-3-methyl glucoside distearate, 2 parts behenol, 2 parts decyl glucoside, 0.5 parts carbomer, 0.5 parts C10-30 alkanol acrylate crosspolymer, 0.2 parts xanthan gum, 2.5 parts diol preservative, 0.5 parts ethylhexyl glycerin, 0.5 parts vitamin E, 0.2 parts active ingredient, and 71.6 parts water; The active ingredients have a mass ratio of purslane extract, hosta extract, gentian extract, and epiphyllum extract of 0.2:0.6:1.1. In the diol preservative, the mass ratio of 1,2-hexanediol to 1,2-pentanediol is 1:1.3.

[0029] (5) Preparation method of antioxidant sunscreen composition The same as step (5) in Example 1.

[0030] Comparative Example 1 The steps for preparing a sunscreen composition for antioxidant purposes are as follows: (1) Preparation of purslane extract Same as step (1) in Example 1; (2) Raw materials used in antioxidant sunscreen compositions The sunscreen composition for antioxidant purposes, by weight, comprises: 3.5 parts ethylhexyl triazine, 6 parts methylene bis-benzotriazolyl tetramethyl butylphenol, 5 parts glycerin, 2 parts butylene glycol, 1 part 1,3-propanediol, 0.5 parts sodium hyaluronate, 3 parts polyglycerol-3-methyl glucoside distearate, 2 parts behenol, 2 parts decyl glucoside, 0.5 parts carbomer, 0.5 parts C10-30 alkanol acrylate crosspolymer, 0.2 parts xanthan gum, 2.5 parts diol preservative, 0.5 parts ethylhexyl glycerin, 0.5 parts vitamin E, 0.3 parts active ingredient, and 70 parts water; The active ingredient is purslane extract; In the diol preservative, the mass ratio of 1,2-hexanediol to 1,2-pentanediol is 1:1.3.

[0031] (3) Preparation method of antioxidant sunscreen composition The same as step (5) in Example 1.

[0032] Comparative Example 2 The steps for preparing a sunscreen composition for antioxidant purposes are as follows: (1) Preparation of purslane extract Same as step (1) in Example 1; (2) Preparation of Gentiana scabra extract The whole plant of Gentiana scabra was washed, dried and crushed to obtain the powder. The pulverized material was mixed with water at a mass ratio of 1:20 and cooked for 1 hour. The mixture was then filtered to obtain the filtrate. The filtrate was concentrated and dried until the mass of the substance no longer changed, thus obtaining the Gentiana scabra aqueous extract.

[0033] (3) Preparation of Epiphyllum extract Same as step (3) in Example 1; (4) Raw materials used in antioxidant sunscreen compositions Same as step (4) in Example 1; (5) Preparation method of antioxidant sunscreen composition The same as step (5) in Example 1.

[0034] Comparative Example 3 The steps for preparing a sunscreen composition for antioxidant purposes are as follows: (1) Preparation of purslane extract Same as step (1) in Example 1; (2) Preparation of Gentiana scabra extract Same as step (2) in Example 1; (3) Preparation of Epiphyllum extract Clean the petals of the epiphyllum, dry them, and crush them to obtain the crushed material; The pulverized material was mixed with water at a mass ratio of 1:20 and cooked for 1 hour. The mixture was then filtered to obtain the filtrate. The filtrate was concentrated and dried until the quality of the substance no longer changed, thus obtaining the Epiphyllum oxypetalum water extract.

[0035] (4) Raw materials used in antioxidant sunscreen compositions Same as step (4) in Example 1; (5) Preparation method of antioxidant sunscreen composition The same as step (5) in Example 1.

[0036] Comparative Example 4 The steps for preparing a sunscreen composition for antioxidant purposes are as follows: (1) Preparation of purslane extract Same as step (1) in Example 1; (2) Preparation of Gentiana scabra extract Clean the whole plant of Gentiana scabra, dry it, and then crush it to obtain the crushed material; The pulverized material was mixed with a 65% ethanol solution at a mass-to-volume ratio of 1g:15mL, and microwaved at 250w and 48℃ for 20min to obtain a microwave extract. The microwave extract was filtered, and the filtrate was concentrated and dried until the mass of the substance no longer changed, thus obtaining the Gentiana scabra extract.

[0037] (3) Preparation of Epiphyllum extract Same as step (3) in Example 1; (4) Raw materials used in antioxidant sunscreen compositions Same as step (4) in Example 1; (5) Preparation method of antioxidant sunscreen composition The same as step (5) in Example 1.

[0038] Comparative Example 5 The steps for preparing a sunscreen composition for antioxidant purposes are as follows: (1) Preparation of purslane extract Same as step (1) in Example 1; (2) Preparation of Gentiana scabra extract Same as step (2) in Example 1; (3) Preparation of Epiphyllum extract The petals of Epiphyllum oxypetalum were subjected to supercritical CO2 extraction at a pressure of 15 MPa, a temperature of 40 °C, and a time of 30 min to obtain Epiphyllum oxypetalum residue and extract (the extract is referred to as Epiphyllum oxypetalum extract). (4) Raw materials used in antioxidant sunscreen compositions Same as step (4) in Example 1; (5) Preparation method of antioxidant sunscreen composition The same as step (5) in Example 1.

[0039] Comparative Example 6 The steps for preparing a sunscreen composition for antioxidant purposes are as follows: (1) Preparation of purslane extract Same as step (1) in Example 1; (2) Preparation of Gentiana scabra extract Same as step (2) in Example 1; (3) Preparation of Epiphyllum extract Same as step (3) in Example 1; (4) Raw materials used in antioxidant sunscreen compositions The sunscreen composition for antioxidant purposes, by weight, comprises: 3.5 parts ethylhexyl triazine, 6 parts methylene bis-benzotriazolyl tetramethyl butylphenol, 5 parts glycerin, 2 parts butylene glycol, 1 part 1,3-propanediol, 0.5 parts sodium hyaluronate, 3 parts polyglycerol-3-methyl glucoside distearate, 2 parts behenol, 2 parts decyl glucoside, 0.5 parts carbomer, 0.5 parts C10-30 alkanol acrylate crosspolymer, 0.2 parts xanthan gum, 2.5 parts diol preservative, 0.5 parts ethylhexyl glycerin, 0.5 parts vitamin E, 0.3 parts active ingredient, and 70 parts water; The active ingredients have a mass ratio of purslane extract, hosta extract, gentian extract, and epiphyllum extract of 1:1:1. In the diol preservative, the mass ratio of 1,2-hexanediol to 1,2-pentanediol is 1:1.3.

[0040] (5) Preparation method of antioxidant sunscreen composition The same as step (5) in Example 1.

[0041] Comparative Example 7 The steps for preparing a sunscreen composition for antioxidant purposes are as follows: (1) Preparation of purslane extract Same as step (1) in Example 1; (2) Preparation of Gentiana scabra extract Same as step (2) in Example 1; (3) Preparation of Epiphyllum extract Same as step (3) in Example 1; (4) Raw materials used in antioxidant sunscreen compositions The sunscreen composition for antioxidant purposes, by weight, comprises: 3.5 parts ethylhexyl triazine, 6 parts methylene bis-benzotriazolyl tetramethyl butylphenol, 5 parts glycerin, 2 parts butylene glycol, 1 part 1,3-propanediol, 0.5 parts sodium hyaluronate, 3 parts polyglycerol-3-methyl glucoside distearate, 2 parts behenol, 2 parts decyl glucoside, 0.5 parts carbomer, 0.5 parts C10-30 alkanol acrylate crosspolymer, 0.2 parts xanthan gum, 2.5 parts diol preservative, 0.5 parts ethylhexyl glycerin, 0.5 parts vitamin E, 0.3 parts active ingredient, and 70 parts water; The active ingredients have a mass ratio of purslane extract, hosta extract, gentian extract, and epiphyllum extract of 0.2:0.6:1.1. The diol preservative is 1,2-hexanediol.

[0042] (5) Preparation method of antioxidant sunscreen composition The same as step (5) in Example 1.

[0043] Sun Protection Factor (SPF) Measurement The sun protection factor (SPF) values ​​of the sun protection compositions prepared in Examples 1-2 and Comparative Examples 1-7 were measured using a sun protection factor meter. Each sample was tested in triplicate. The SPF values ​​and PA values ​​(sun protection factor and PA values) of different sun protection compositions were statistically analyzed. The results are shown in Table 1 (only integers are entered in Table 1).

[0044] Table 1. SPF and PA values ​​of different sunscreen compositions

[0045] As can be seen from the data in Table 1, the sunscreen compositions prepared in Examples 1-2 have excellent sunscreen effects. Compared with the comparative examples, the sunscreen compositions in the examples have higher SPF and PA values.

[0046] Antioxidant efficacy test Vitamin C was used as the positive group (vitamin C was dissolved in 95% ethanol solution to obtain vitamin C with a concentration of 1 mg / mL), and the sunscreen compositions prepared in Examples 1-2 and Comparative Examples 1-7 were used as test solutions (each test substance was dissolved in 95% ethanol solution to obtain each test solution with a concentration of 0.01 g / mL). DPPH was dissolved in 95% ethanol solution to obtain a 0.06 mmol / L DPPH solution for later use. Using the 95% ethanol solution as a reference solution, the baseline was scanned, and the concentration of the 0.06 mmol / L DPPH solution at 400 °C was measured. The maximum absorption wavelength at 600nm is 517nm.

[0047] Group A0: Take 4 mL of 0.06 mmol / L DPPH solution into a 10 mL transparent tube, add 1 mL of 95% ethanol solution, mix and stabilize, and then measure the absorbance at 517 nm. Ar group: Take 4 mL of 0.06 mmol / L DPPH solution into a 10 mL transparent tube, then add 1 mL of each test solution, mix and stabilize, and measure the absorbance at 517 nm. Group As: Take 4 mL of 95% ethanol solution into a 10 mL transparent tube, then add 1 mL of each test solution, mix and stabilize, and measure the absorbance at 517 nm. Wherein, free radical scavenging rate (%) = [1 [(Ar-As) / A0]×100%; The free radical scavenging rate results for different test solutions are shown in Table 2.

[0048] Table 2 Free radical scavenging rates of different test solutions

[0049] As shown in Table 2, the sunscreen compositions prepared in Example 1 or Example 2 have an anti-free radical effect comparable to 1 mg / mL vitamin E, exhibiting strong antioxidant capacity. Therefore, in practical applications, they can effectively eliminate free radicals that negatively impact the skin, reducing skin damage and aging caused by ultraviolet radiation. However, altering the preparation method of the active ingredients or the amount of each raw material in the comparative examples did not utilize the composition's effectiveness. Furthermore, although the sunscreen composition prepared in Comparative Example 5 has a good anti-free radical effect, its SPF and PA values ​​are low.

[0050] Human skin patch test In accordance with the relevant requirements of the "Human Skin Patch Test" in the 2015 edition of the "Cosmetic Safety Technical Specifications", 31 volunteers were selected, including 30 females and 1 male, aged 18-50 years.

[0051] The sunscreen compositions prepared in Examples 1 and 2 were tested according to the test methods specified in the 2015 edition of the "Cosmetic Safety Technical Specifications". The skin reactions of volunteers were observed at 0.5h, 24h and 48h respectively.

[0052] The results showed that all volunteer subjects had negative experimental results, with no adverse skin reactions. Therefore, the sunscreen compositions prepared in the examples and comparative examples do not cause allergic reactions, are non-irritating, and have high safety.

[0053] User experience test Forty volunteers were selected in accordance with the relevant requirements of the "Human Skin Patch Test" in the 2015 edition of the "Cosmetic Safety Technical Specifications". There were 30 females and 10 males, aged 18-50.

[0054] The sunscreen compositions prepared in Examples 1 and 2 were used as test substances. Each test substance was applied according to the volunteers' usual application habits (the interval between the application of the two test substances was 4 hours). The degree of refreshing and non-sticky feeling was then evaluated. The results are shown in Table 3.

[0055] Evaluation Criteria: A (Positive user experience): ≥32 volunteers did not find it greasy or heavy; B (General user experience): ≥20 and <32 volunteers did not feel it was greasy or heavy; C (Poor user experience): <20 volunteers did not feel it was greasy or heavy.

[0056] Table 3. Results of user experience with different test substances

[0057] As shown in Table 3, the sunscreen compositions prepared in Examples 1 and 2 are refreshing and non-sticky, providing a good user experience.

[0058] In summary, this invention, by adding ingredients such as ethylhexyl triazine ketone, methylene bis-benzotriazolyl tetramethylbutylphenol, and vitamin E, absorbs specific wavelengths of ultraviolet light through its molecular structure, thus reducing the irritation caused by ultraviolet radiation. The addition of polyglycerol-3-methylglucose distearate, carbomer, and xanthan gum not only helps prevent product delamination or inactivation but also reduces the irritation of chemical sunscreens. Furthermore, the addition of purslane extract, gentian extract, and epiphyllum extract enhances the skin's antioxidant properties. Therefore, the sunscreen composition provided by this invention possesses advantages in physical barrier reflection, chemical absorption and conversion, and synergistic effects. It is stable, has a good skin feel, and is highly safe, providing efficient antioxidant protection and significant sun protection while also offering broad-spectrum protection and a pleasant user experience.

[0059] Although the above embodiments have provided a detailed description of the present invention, they are only some embodiments of the present invention, and not all embodiments. People can obtain other embodiments based on these embodiments without creative effort, and these embodiments all fall within the protection scope of the present invention.

Claims

1. A sunscreen composition for antioxidant use, characterized by, The product comprises, by weight parts, the following raw materials: 2.5-3.5 parts ethylhexyl triazine ketone, 5-6 parts methylene bis-benzotriazolyl tetramethyl butylphenol, 4-5 parts glycerin, 1-2 parts butylene glycol, 0.5-1 part 1,3-propanediol, 0.1-0.5 parts sodium hyaluronate, 1-3 parts polyglycerol-3-methyl glucoside distearate, 1-2 parts behenol, 1-2 parts decyl glucoside, 0.1-0.5 parts carbomer, 0.1-0.5 parts C10-30 alkanol acrylate crosspolymer, 0.05-0.2 parts xanthan gum, 1.5-2.5 parts diol preservative, 0.1-0.5 parts ethylhexyl glycerin, 0.1-0.5 parts vitamin E, 0.08-0.3 parts active ingredient, and 50-70 parts water; The diol preservatives include: 1,2-hexanediol and 1,2-pentanediol; The active ingredients include: purslane extract, hosta extract, gentian extract, and epiphyllum extract.

2. The sunscreen composition of claim 1, wherein The mass ratio of Portulaca oleracea extract, Gentiana scabra extract, and Epiphyllum oxypetalum extract in the active components is 0.2-0.6:0.5-0.9:1-1.

5. In the diol preservative, the mass ratio of 1,2-hexanediol to 1,2-pentanediol is 1:1-2.

5.

3. The sunscreen composition according to claim 1 or 2, characterized in that, The product comprises, by weight parts, the following raw materials: 3.5 parts ethylhexyl triazine ketone, 6 parts methylene bis-benzotriazolyl tetramethyl butylphenol, 5 parts glycerin, 2 parts butylene glycol, 1 part 1,3-propanediol, 0.5 parts sodium hyaluronate, 3 parts polyglycerol-3-methyl glucoside distearate, 2 parts behenol, 2 parts decyl glucoside, 0.5 parts carbomer, 0.5 parts C10-30 alkanol acrylate crosspolymer, 0.2 parts xanthan gum, 2.5 parts diol preservative, 0.5 parts ethylhexyl glycerin, 0.5 parts vitamin E, 0.3 parts active ingredient, and 70 parts water; The active ingredients have a mass ratio of purslane extract, hosta extract, gentian extract, and epiphyllum extract of 0.2:0.6:1.

1. In the diol preservative, the mass ratio of 1,2-hexanediol to 1,2-pentanediol is 1:1.

3.

4. The sunscreen composition according to claim 1 or 2, characterized in that, The product comprises, by weight parts, the following raw materials: 3 parts ethylhexyl triazine ketone, 5 parts methylene bis-benzotriazolyl tetramethyl butylphenol, 5 parts glycerin, 2 parts butanediol, 1 part 1,3-propanediol, 0.5 parts sodium hyaluronate, 3 parts polyglycerol-3-methyl glucoside distearate, 2 parts behenol, 2 parts decyl glucoside, 0.5 parts carbomer, 0.5 parts C10-30 alkanol acrylate crosspolymer, 0.2 parts xanthan gum, 2.5 parts diol preservative, 0.5 parts ethylhexyl glycerin, 0.5 parts vitamin E, 0.2 parts active ingredient, and 71.6 parts water; The active ingredients have a mass ratio of purslane extract, hosta extract, gentian extract, and epiphyllum extract of 0.2:0.6:1.

1. In the diol preservative, the mass ratio of 1,2-hexanediol to 1,2-pentanediol is 1:1.

3.

5. The sunscreen composition according to claim 1 or 2, characterized in that, The purslane extract includes: purslane water extract; The preparation method of the Gentiana rhodantha extract is as follows: the whole plant of Gentiana rhodantha is mixed with an acetone solution to perform microwave extraction, solid-liquid separation and concentration drying to obtain the Gentiana rhodantha extract; the volume concentration of the acetone solution is 55%-65%.

6. The sunscreen composition according to claim 5, wherein During the microwave extraction, the mass-volume ratio of the whole plant of Gentiana rhodantha to the acetone solution is 1g:12-15mL; The power of the microwave extraction is 250-350w, the time is 20-30min, and the temperature is 48-53℃.

7. The sunscreen composition according to claim 1 or 2, characterized in that, The preparation method of the Epiphyllum extract is as follows: the petals of Epiphyllum are subjected to supercritical CO2 extraction with an ethanol solution with a volume concentration of 3%-8% as an entraining agent to obtain Epiphyllum residue; the Epiphyllum residue is mixed with an ethanol solution with a volume concentration of 30-40% for immersion, and after solid-liquid separation, activated carbon is added, and then filtration is performed to obtain a filtrate; after the ethanol in the filtrate is recovered, spray drying is performed to obtain the Epiphyllum extract.

8. The sunscreen composition according to claim 7, wherein During the supercritical CO2 extraction, the pressure is 15-25MPa, the temperature is 40-50℃, and the time is 30-40min.

9. The sunscreen composition of claim 7, wherein, During the mixing immersion, the mass-volume ratio of the Epiphyllum residue to the ethanol solution with a volume concentration of 30-40% is 1g:5.5-7.5mL; The temperature of the mixing immersion is 25-30℃, and the time is 5-8h.

10. Process for the preparation of a sunscreen composition according to any one of claims 1 to 9, characterized in that, The method comprises the following steps: S1, oil phase preparation: ethylhexyl triazone, polyglyceryl-3 methylglucose distearate and behenyl alcohol are dissolved at 70-75℃ to obtain an oil phase; S2, water phase preparation: glycerin, butylene glycol, 1,3-propanediol and water are mixed to obtain a first mixture; the first mixture and carbomer are uniformly mixed at 70-75℃ to obtain a second mixture; Methylene bis-benzotriazolyl tetramethylbutylphenol and 1,2-hexanediol are uniformly mixed to obtain a third mixture; the second mixture and the third mixture are mixed to obtain a water phase; S3, emulsification stage: after the oil phase and the water phase are mixed, xanthan gum, sodium hyaluronate and active ingredients are added at 40-45℃ and uniformly stirred to obtain an emulsified product; S4, late adjustment: the emulsified product, vitamin E, 1,2-pentanediol, decyl glucoside, C10-30 alkyl acrylate crosspolymer and ethylhexylglycerin are mixed at 35-40℃, the pH is adjusted to 5.5-6.0 to obtain a sunscreen composition.

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