Microcirculation promoting essential oil based on carbonic acid hot spring extract and preparation method

Abstract

The invention discloses microcirculation promoting essential oil based on carbonic acid hot spring extract and a preparation method, and the essential oil comprises the following components by mass: 10%-30% of carbonic acid hot spring extract, 50%-70% of plant essential oil base oil, 4%-7% of a liquid crystal forming agent, 1%-3% of a fragrance glowing matrix, 1%-2% of an anti-aging brightening unit, 0.1%-0.5% of a tip penetration enhancer, and 0.5%-2% of an antioxidant, the carbonated hot spring extract is carbonated spring liquid encapsulated by microcapsules and contains dissolved carbon dioxide gas and mineral ions of calcium, magnesium and sodium. According to the microcirculation promoting essential oil based on the carbonic acid hot spring extract, microencapsulation and liquid crystal structure technologies are adopted, it is ensured that CO can stably exist in an essential oil matrix for a long time, barrier repairing and active matter conveying are enhanced, slow release and transdermal absorption of active matter are optimized, CO2 and mineral ions can more easily and directly reach a capillary region, and the microcirculation promoting essential oil is more beneficial to improving the microcirculation promoting effect of the carbonic acid hot spring extract. The skin metabolism is promoted, and the problems of dark skin color and local tissue fluid accumulation caused by unsmooth circulation are solved.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of functional essential oil technology, in particular to a microcirculation promoting essential oil based on carbonated spring extract and a preparation method thereof. BACKGROUND

[0002] Microcirculation is the most basic unit in the blood circulation system, directly involved in the exchange of substances between cells and blood, and microcirculation disorder is considered as an important inducement for many chronic diseases (such as hypertension, diabetic complications, cold hands and feet, etc.). Carbonated spring therapy has been clinically proven to effectively promote microcirculation for a long time. The mechanism is that carbon dioxide molecules in carbonated spring are absorbed into blood through skin pores, causing endothelial cells to release nitric oxide, promoting vasodilation, reducing blood flow resistance, and improving local blood circulation. However, existing products containing carbonated spring mainly rely on vasoactive substances or plant volatile components, and their transdermal behavior is uncontrollable, most of which are retained on the surface of the stratum corneum, and it is difficult to precisely act on the microvascular network of the dermis. The mechanism is also relatively single, and lacks multi-level and physiological synergistic regulation of the microcirculation system. At the same time, natural carbonated spring is mainly distributed in specific geological areas, and consumers need to travel a long distance to enjoy its therapeutic effect, which has strong geographical limitations. In addition, the carbon dioxide gas in the spring is easy to volatilize, and existing skin care products can only retain minerals, losing the immediate penetration and blood vessel starting function of key gases such as CO2, resulting in unsatisfactory actual effect. In addition, the essential oil system of existing products has poor stability, and the active ingredients are easy to lose activity. Volatile components in conventional formulations are easy to lose, and light and heat sensitive substances are easy to degrade. Different polar components are easy to separate. Even if the physical stability is improved by thickening or emulsification, the bioavailability and skin feel of active substances are often sacrificed. Programmed release cannot be achieved, and may cause adverse experiences such as greasy and stuffy skin. Therefore, the present application provides a microcirculation promoting essential oil based on carbonated spring extract and a preparation method thereof to solve the problems raised in the background art. SUMMARY

[0003] The present application aims to provide a microcirculation promoting essential oil based on carbonated spring extract and a preparation method thereof, which uses microencapsulation and liquid crystal structure technology to ensure the long-term stability of CO2 in the essential oil matrix, enhance barrier repair and active substance transport, optimize the slow release and transdermal absorption of active substances, and make CO2 and mineral ions more easily reach the microvascular area, promote skin metabolism, and improve the problem of local tissue fluid accumulation caused by poor circulation, to solve the problems raised in the background art.

[0004] To achieve the above-mentioned purpose, the present application provides the following technical solutions: A microcirculation promoting essential oil based on carbonated spring extract, comprising the following components in mass content: carbonated spring extract 10%-30%, plant essential oil base oil 50%-70%, liquid crystal forming agent 4%-7%, fragrance activation matrix 1%-3%, anti-aging lightening unit 1%-2%, advanced penetration enhancer 0.1%-0.5%, antioxidant 0.5%-2%, wherein the carbonated spring extract is a microencapsulated carbonated spring liquid containing dissolved carbon dioxide gas and calcium, magnesium, sodium mineral ions, and the encapsulation wall material is a gelatin-arabic gum composite wall material; the liquid crystal forming agent is a complex of lecithin and cetyl alcohol at a weight ratio of 2:1.

[0005] As a further scheme of the present application: the plant essential oil base oil is one or more of a complex of white pool flower seed oil, squalane and jojoba oil, with an unsaturated fatty acid content of ≥80%.

[0006] As a further scheme of the present application: the fragrance activation matrix is a mixture of rose essential oil and rosemary essential oil at a weight ratio of 1:1.

[0007] As a further scheme of the present application: the anti-aging lightening unit is a mixture of bakuchiol and 3-O-ethyl ascorbic acid at a weight ratio of 1:1.

[0008] As a further scheme of the present application: the advanced penetration enhancer is a peptide amino acid surfactant.

[0009] As a further scheme of the present application: the concentration of carbon dioxide in the microencapsulated carbonated spring extract is ≥1000ppm, the total mineral content is 1.5-2.5g / L, and the pH value is 5.0-5.8.

[0010] A preparation method of a microcirculation promoting essential oil based on carbonated spring extract, the method comprising the following steps: Step one, collecting natural carbonated spring water, filtering out impurities through a 0.22μm microporous filter membrane to obtain carbonated spring liquid; Step two, mixing the carbonated spring liquid with a gelatin-arabic gum composite wall material at a mass ratio of 1:1, and homogenously stirring at a stirring rate of 5000rpm at 45-50℃ for 10-15min to form an emulsion, then preparing microcapsules by spray drying method to obtain microencapsulated carbonated spring extract powder; Step three, selecting a plant essential oil base oil with an unsaturated fatty acid content of not less than 80%, purifying by molecular distillation technology at 90-100℃ and a vacuum degree of ≤10Pa to remove impurities and odors, and obtaining the pretreated plant essential oil base oil; Step four, mix 10%-30% microencapsulated carbonated spring extract powder, 50%-70% pretreated plant essential oil base oil, 4%-7% liquid crystal forming agent, 1%-3% fragrance activation matrix, 1%-2% anti-aging lightening unit, 0.1%-0.5% advanced penetration enhancer, and 0.5%-2% antioxidant vitamin E by weight percentage, and homogenize and emulsify at a stirring rate of 10,000-12,000 rpm at 25-30°C for 10-15 min to obtain an essential oil mixture; Step five, under a sterile environment, the essential oil mixture is sterilized by filtering through a 0.22 μm microporous filter, and then filled into a pre-sterilized brown glass bottle by nitrogen filling and sealed to prevent oxidation of active ingredients; Step six, randomly select the filled finished product for testing to ensure that the pH value, viscosity, stability, and microbial indicators of the finished product meet the quality standards.

[0011] As a further scheme of the present application, the encapsulation efficiency of the carbonated spring extract microcapsule powder in step two is ≥90%.

[0012] As a further scheme of the present application, the filling environment temperature of the essential oil mixture in step five is 20-25°C, and the temperature-sensitive active substance is added when the base oil is cooled to <40°C.

[0013] Compared with the prior art, the present application has the advantages that the preparation method of the microcirculation promoting essential oil based on carbonated spring extract proposed in the present application integrates the key components in the carbonated spring extract that promote microcirculation through microencapsulation, accelerates the removal of metabolic waste, and enhances the self-repairing ability of the skin. Then, a liquid crystal forming agent is introduced to spontaneously form a lamellar structure on the skin, mimic the skin lipid barrier, encapsulate the carbon dioxide and mineral ions in the carbonated spring, ensure the long-term stable existence of the active ingredients in the essential oil matrix, avoid volatilization and invalidation, optimize the sustained release and transdermal absorption of the active substances, make them directly reach the dermis to promote capillary blood flow increase, promote skin metabolism, improve dull skin color, and improve the problem of local tissue fluid accumulation caused by poor circulation. Moreover, the mild and long-lasting promotion of capillary blood flow increase produces a mild warming sensation, improves user comfort, and ensures the bioavailability and targeting efficiency of subsequent anti-aging and lightening active ingredients. BRIEF DESCRIPTION OF DRAWINGS

[0014] Figure 1 The flowchart of the preparation method of the microcirculation promoting essential oil based on carbonated spring extract according to an embodiment of the present application is shown in FIG. 1. Figure 2 The action schematic diagram of the microcirculation promoting essential oil based on carbonated spring extract according to an embodiment of the present application is shown in FIG. 2. DETAILED DESCRIPTION

[0015] Example 1 In combination Figure 1 and Figure 2 As shown in the figure, select CO2 concentration ≥ 1500 ppm, mineral content of 2.0 g / L, PH value of 6.5 natural carbonic acid hot spring, and prepare carbonic acid hot spring extract microcapsule powder with gelatin-Arabian gum solution as wall material according to the mass ratio of 1:1. The method for preparing carbonic acid hot spring extract microcapsule powder is as follows: Step one, select CO2 concentration ≥ 1500 ppm, mineral content of 2.0 g / L, PH value of 6.5 natural carbonic acid hot spring, filter impurities through 0.22 μm microporous filter membrane, and obtain carbonic acid spring liquid; Step two, mix the carbonic acid spring liquid with the gelatin-Arabian gum composite wall material according to the mass ratio of 1:1, homogenize and stir at 45-50°C and a stirring rate of 5000 rpm for 10 min to form an emulsion, then prepare microcapsules by spray drying method, control the inlet air temperature at 120°C and the outlet air temperature at 70°C, and obtain carbonic acid hot spring extract microcapsule powder with an encapsulation efficiency of 92%.

[0016] The carbonic acid hot spring extract microcapsule powder prepared by the above method obtains a white powder of carbonic acid hot spring extract microcapsule with a PH value of 5.2. After detection, its encapsulation efficiency is ≥90%, and after sealed and stored in the dark for 30 days at room temperature, the CO2 residual rate can still be maintained at more than 85%, thereby improving the stability of the core components of carbonic acid hot spring extract.

[0017] Example 2 Based on Example 1, 20% carbonic acid hot spring extract microcapsule powder, 60% white pool flower seed oil, 5% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 2% fragrance activation matrix (rose essential oil: rosemary essential oil = 1:1), 1.5% anti-aging lightening unit (bakuchiol: 3-O-ethyl ascorbic acid = 1:1), 0.3% advanced penetration enhancer (peptide amino acid surfactant), and 1.2% vitamin E are used to prepare a microcirculation promoting essential oil based on carbonic acid hot spring extract. The preparation method of the microcirculation promoting essential oil based on carbonic acid hot spring extract is as follows: Step one, purify the white pool flower seed oil by molecular distillation technology at 95°C and a vacuum degree of ≤10 Pa, remove impurities and odors, and obtain pretreated white pool flower seed oil; Step 2: By weight percentage, mix 20% carbonated hot spring extract microcapsule powder, 60% meadowfoam seed oil, 5% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 2% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 1.5% anti-aging brightening unit (bakuchiol: 3-O-ethyl ascorbic acid = 1:1), 0.3% advanced penetration enhancer (peptide amino acid surfactant), and 1.2% vitamin E, and preheat to 30℃. Then, homogenize and emulsify the mixture at a stirring speed of 10,000 rpm for 12 minutes to obtain the essential oil mixture. Step 3: In a sterile environment at 25°C, the essential oil mixture is filtered through a 0.22μm microporous membrane for sterilization. Then, it is filled with nitrogen and sealed in pre-sterilized glass bottles to isolate oxygen and light and prevent oxidation of active ingredients. Step 4: Randomly select finished products after filling for testing to ensure that the pH value, viscosity, stability and microbial indicators of the finished products meet the quality standards.

[0018] The microcirculation-promoting essential oil based on carbonated hot spring extract prepared using the above method is a pale yellow, transparent oily liquid with a pH of 5.5 and a CO2 sustained-release time of ≥4h. After an accelerated stability test at 40℃ for 30 days, the product showed no stratification, precipitation, or discoloration, and the total bacterial count was <10 CFU / g. After product use, facial microcirculation blood perfusion increased by 25%, skin radiance improved by 20%, and dark circles were reduced by 30%, demonstrating the synergistic effect of microcapsule and liquid crystal technology.

[0019] Example 3 Based on Example 1, a microcirculation-promoting essential oil based on carbonated hot spring extract was prepared using 25% carbonated hot spring extract microcapsule powder, 55% squalane, 6% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 3% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 2% anti-aging and brightening unit (bakuchiol: 3-O-ethyl ascorbic acid = 1:1), 0.5% advanced penetration enhancer (peptide amino acid surfactant), and 2% vitamin E. The preparation method of the microcirculation-promoting essential oil based on carbonated hot spring extract is as follows: Step 1: Squalane is purified by molecular distillation at 95℃ and a vacuum of ≤10Pa to remove impurities and odors, thus obtaining pretreated squalane. Step 2: By weight percentage, mix 25% carbonated hot spring extract microcapsule powder, 55% squalane, 6% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 3% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 2% anti-aging brightening unit (bakuchiol: 3-O-ethyl ascorbic acid = 1:1), 0.5% advanced penetration enhancer (peptide amino acid surfactant), and 2% vitamin E, and preheat to 30°C. Then, homogenize and emulsify the mixture at a stirring speed of 12000 rpm for 12 minutes to obtain the essential oil mixture. Step 3: In a sterile environment at 25°C, the essential oil mixture is filtered through a 0.22μm microporous membrane for sterilization. Then, it is filled with nitrogen and sealed in pre-sterilized glass bottles to isolate oxygen and light and prevent oxidation of active ingredients. Step 4: Randomly select finished products after filling for testing to ensure that the pH value, viscosity, stability and microbial indicators of the finished products meet the quality standards.

[0020] The microcirculation-promoting essential oil based on carbonated hot spring extract prepared using the above method is a pale yellow, transparent oily liquid with a pH of 5.4 and a CO2 sustained-release time of ≥5h. After an accelerated stability test at 40℃ for 30 days, the product showed no stratification, precipitation, or discoloration, and the total bacterial count was <10 CFU / g. After use, skin collagen density increased by 15%, skin radiance improved by 30%, and edema was reduced by 40%. Furthermore, laser speckle contrast imaging verified a 50% increase in microcirculation-promoting efficiency, highlighting the anti-aging advantages of the high-concentration formula.

[0021] Example 4 Based on Example 1, a microcirculation-promoting essential oil based on carbonated hot spring extract was prepared using 15% carbonated hot spring extract microcapsule powder, 65% jojoba oil, 4% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 1% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 1% anti-aging and brightening unit (bakuchiol: 3-O-ethyl ascorbic acid = 1:1), 0.1% advanced penetration enhancer (peptide amino acid surfactant), and 0.9% vitamin E. The preparation method of the microcirculation-promoting essential oil based on carbonated hot spring extract is as follows: Step 1: Jojoba oil is purified by molecular distillation at 95℃ and a vacuum of ≤10Pa to remove impurities and off-odors, thus obtaining pretreated jojoba oil. Step 2: By weight percentage, mix 15% carbonated hot spring extract microcapsule powder, 65% jojoba oil, 4% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 1% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 1% anti-aging brightening unit (bakuchiol: 3-O-ethyl ascorbic acid = 1:1), 0.1% advanced penetration enhancer (peptide amino acid surfactant), and 0.9% vitamin E, and preheat to 25°C. Then, homogenize and emulsify the mixture at a stirring speed of 10,000 rpm for 10 minutes to obtain the essential oil mixture. Step 3: In a sterile environment at 25°C, the essential oil mixture is filtered through a 0.22μm microporous membrane for sterilization. Then, it is filled with nitrogen and sealed in pre-sterilized glass bottles to isolate oxygen and light and prevent oxidation of active ingredients. Step 4: Randomly select finished products after filling for testing to ensure that the pH value, viscosity, stability and microbial indicators of the finished products meet the quality standards.

[0022] The microcirculation-promoting essential oil based on carbonated hot spring extract prepared using the above method is a pale yellow, transparent, oily liquid with a pH of 5.7 and a CO2 sustained-release time of ≥4.5h. After an accelerated stability test at 40℃ for 30 days, the product showed no stratification, precipitation, or discoloration, and the total bacterial count was <10 CFU / g. After use, the barrier repair score improved by 20%, and the edema reduction rate was 35%. The microbial indicators met the cosmetic safety standards. This formula is gentle and non-irritating, suitable for long-term use, and effectively solves the problem of cold hands and feet.

[0023] Example 5 Based on Example 1, a microcirculation-promoting essential oil based on carbonated hot spring extract was prepared using 20% ​​carbonated hot spring extract microcapsule powder, 60% compound plant essential oil base oil (30% meadowfoam seed oil, 30% squalane, total unsaturated fatty acid content ≥80%), 5% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 2% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 1.5% anti-aging and brightening unit (psoralen: 3-O-ethyl ascorbic acid = 1:1), 0.3% advanced penetration enhancer (peptide amino acid surfactant), and 1.2% vitamin E. The preparation method of the microcirculation-promoting essential oil based on carbonated hot spring extract is as follows: Step 1: The meadowfoam seed oil and squalane are purified by molecular distillation at 95℃ and vacuum degree ≤10Pa to remove impurities and odors, and then the pretreated meadowfoam seed oil and squalane are obtained. The pretreated meadowfoam seed oil and squalane are then mixed at a mass ratio of 1:1 to obtain a compound plant essential oil base oil. Step 2: By weight percentage, mix 20% carbonated hot spring extract microcapsule powder, 60% compound plant essential oil base oil (30% meadowfoam seed oil, 30% squalane, total unsaturated fatty acid content ≥80%), 5% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 2% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 1.5% anti-aging brightening unit (bakuchiol: 3-O-ethyl ascorbic acid = 1:1), 0.3% advanced penetration enhancer (peptide amino acid surfactant), and 1.2% vitamin E, and preheat to 25℃. Then, homogenize and emulsify the mixture at a stirring speed of 10000 rpm for 10 minutes to obtain the essential oil mixture. Step 3: In a sterile environment at 25°C, the essential oil mixture is filtered through a 0.22μm microporous membrane for sterilization. Then, it is filled with nitrogen and sealed in pre-sterilized glass bottles to isolate oxygen and light and prevent oxidation of active ingredients. Step 4: Randomly select finished products after filling for testing to ensure that the pH value, viscosity, stability and microbial indicators of the finished products meet the quality standards.

[0024] The microcirculation-promoting essential oil based on carbonated hot spring extract, prepared using the above method, is a pale yellow, transparent oily liquid with a pH of 5.5 and a CO2 sustained-release time of ≥4 hours. After an accelerated stability test at 40℃ for 30 days, the product showed no stratification, precipitation, or discoloration. The CO2 residue rate was ≥85%, the 3-O-ethyl ascorbic acid retention rate was >90%, the active ingredient retention rate was high, and the total bacterial count was <10 CFU / g. After product use, facial microcirculation blood perfusion increased by 28%, skin radiance improved by 25%, and dark circles decreased by 35%. The compound base oil combines the high stability of meadowfoam seed oil with the skin-friendly properties of squalane, synergistically enhancing the barrier repair effect.

[0025] Example 6 Based on Example 1, a microcirculation-promoting essential oil based on carbonated hot spring extract was prepared using 20% ​​carbonated hot spring extract microcapsule powder, 65% compound plant essential oil base oil (43.3% meadowfoam seed oil, 21.7% jojoba oil, total unsaturated fatty acid content ≥80%), 4% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 1% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 1% anti-aging and brightening unit (psoralen: 3-O-ethyl ascorbic acid = 1:1), 0.1% advanced penetration enhancer (peptide amino acid surfactant), and 0.9% vitamin E. The preparation method of the microcirculation-promoting essential oil based on carbonated hot spring extract is as follows: Step 1: The meadowfoam seed oil and jojoba oil are purified by molecular distillation at 95℃ and vacuum degree ≤10Pa to remove impurities and odors, and then the pretreated meadowfoam seed oil and jojoba oil are obtained. The pretreated meadowfoam seed oil and jojoba oil are then mixed at a mass ratio of 1:1 to obtain a compound plant essential oil base oil. Step 2: By weight percentage, mix 20% carbonated hot spring extract microcapsule powder, 65% compound plant essential oil base oil (43.3% meadowfoam seed oil, 21.7% jojoba oil, total unsaturated fatty acid content ≥80%), 4% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 1% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 1% anti-aging brightening unit (bakuchiol: 3-O-ethyl ascorbic acid = 1:1), 0.1% advanced penetration enhancer (peptide amino acid surfactant), and 0.9% vitamin E, and preheat to 25℃. Then, homogenize and emulsify the mixture at a stirring speed of 10000 rpm for 10 minutes to obtain the essential oil mixture. Step 3: In a sterile environment at 25°C, the essential oil mixture is filtered through a 0.22μm microporous membrane for sterilization. Then, it is filled with nitrogen and sealed in pre-sterilized glass bottles to isolate oxygen and light and prevent oxidation of active ingredients. Step 4: Randomly select finished products after filling for testing to ensure that the pH value, viscosity, stability and microbial indicators of the finished products meet the quality standards.

[0026] The microcirculation-promoting essential oil based on carbonated hot spring extract prepared using the above method is a pale yellow, transparent oily liquid with a pH of 5.6 and a CO2 sustained-release time of ≥4.5h. After an accelerated stability test at 40℃ for 30 days, the product showed no stratification, precipitation, or discoloration, and its microbial indicators were qualified. After use, the product improved the barrier repair score by 22% and reduced puffiness by 38%. It also has a light and gentle feel, making it suitable for sensitive skin. The base oil is formulated to utilize the antioxidant properties of meadowfoam seed oil and the moisturizing properties of jojoba oil to enhance the product's gentleness.

[0027] Example 7 Based on Example 1, a microcirculation-promoting essential oil based on carbonated hot spring extract was prepared using 20% ​​carbonated hot spring extract microcapsule powder, 65% compound plant essential oil base oil (27.5% squalane, 27.5% jojoba oil, total unsaturated fatty acid content ≥80%), 6% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 3% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 2% anti-aging and brightening unit (bakuchiol: 3-O-ethyl ascorbic acid = 1:1), 0.5% advanced penetration enhancer (peptide amino acid surfactant), and 2% vitamin E. The preparation method of the microcirculation-promoting essential oil based on carbonated hot spring extract is as follows: Step 1: Squalane and jojoba oil are purified by molecular distillation at 95℃ and vacuum degree ≤10Pa to remove impurities and odors, and then pretreated squalane and jojoba oil are obtained. The pretreated squalane and jojoba oil are then mixed at a mass ratio of 1:1 to obtain a compound plant essential oil base oil. Step 2: By weight percentage, mix 20% carbonated hot spring extract microcapsule powder, 65% compound plant essential oil base oil (27.5% squalane, 27.5% jojoba oil, total unsaturated fatty acid content ≥80%), 6% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 3% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 2% anti-aging brightening unit (bakuchiol: 3-O-ethyl ascorbic acid = 1:1), 0.5% advanced penetration enhancer (peptide amino acid surfactant), and 2% vitamin E, and preheat to 25℃. Then, homogenize and emulsify the mixture at a stirring speed of 10000 rpm for 10 minutes to obtain the essential oil mixture. Step 3: In a sterile environment at 25°C, the essential oil mixture is filtered through a 0.22μm microporous membrane for sterilization. Then, it is filled with nitrogen and sealed in pre-sterilized glass bottles to isolate oxygen and light and prevent oxidation of active ingredients. Step 4: Randomly select finished products after filling for testing to ensure that the pH value, viscosity, stability and microbial indicators of the finished products meet the quality standards.

[0028] The microcirculation-promoting essential oil based on carbonated hot spring extract prepared using the above method is a pale yellow, transparent oily liquid with a pH of 5.3 and a CO2 sustained-release time of ≥5.5h. After an accelerated stability test at 40℃ for 30 days, the product showed no stratification, precipitation, or discoloration, and its microbial indicators were qualified. After product use, skin collagen density increased by 18%, microcirculation promotion efficiency improved by 55%, and edema reduction rate was 42%. The compound base oil integrates the permeability of squalane and the stability of jojoba oil, optimizing the anti-aging effect.

[0029] Example 8 Based on Example 1, a microcirculation-promoting essential oil based on carbonated hot spring extract was prepared using 20% ​​carbonated hot spring extract microcapsule powder, 60% compound plant essential oil base oil (20% meadowfoam seed oil, 20% squalane, 20% jojoba oil, total unsaturated fatty acid content ≥80%), 5% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 2% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 1.5% anti-aging and brightening unit (psoralen: 3-O-ethyl ascorbic acid = 1:1), 0.3% advanced penetration enhancer (peptide amino acid surfactant), and 1.2% vitamin E. The preparation method of the microcirculation-promoting essential oil based on carbonated hot spring extract is as follows: Step 1: The meadowfoam seed oil, squalane, and jojoba oil are purified by molecular distillation at 95℃ and a vacuum degree ≤10Pa to remove impurities and off-odors, thus obtaining pretreated meadowfoam seed oil, squalane, and jojoba oil. Then, the pretreated meadowfoam seed oil, squalane, and jojoba oil are mixed at a mass ratio of 1:1 to obtain a compound plant essential oil base oil. Step 2: By weight percentage, mix 20% carbonated hot spring extract microcapsule powder, 60% compound plant essential oil base oil (20% meadowfoam seed oil, 20% squalane, 20% jojoba oil, total unsaturated fatty acid content ≥80%), 5% liquid crystal forming agent (lecithin: cetyl alcohol = 2:1), 2% fragrance revitalizing matrix (rose essential oil: rosemary essential oil = 1:1), 1.5% anti-aging brightening unit (bakuchiol: 3-O-ethyl ascorbic acid = 1:1), 0.3% advanced penetration enhancer (peptide amino acid surfactant), and 1.2% vitamin E, and preheat to 30℃. Then, homogenize and emulsify the mixture at a stirring speed of 10000 rpm for 12 minutes to obtain the essential oil mixture. Step 3: In a sterile environment at 25°C, the essential oil mixture is filtered through a 0.22μm microporous membrane for sterilization. Then, it is filled with nitrogen and sealed in pre-sterilized glass bottles to isolate oxygen and light and prevent oxidation of active ingredients. Step 4: Randomly select finished products after filling for testing to ensure that the pH value, viscosity, stability and microbial indicators of the finished products meet the quality standards.

[0030] The microcirculation-promoting essential oil based on carbonated hot spring extract prepared using the above method is a pale yellow, transparent oily liquid with a pH of 5.6 and a CO2 sustained-release time of ≥4.5h. After an accelerated stability test at 40℃ for 30 days, the product showed no stratification, precipitation, or discoloration, and its microbial indicators were qualified. After product use, facial microcirculation blood perfusion increased by approximately 25%, skin radiance improved by 25%, dark circles decreased by 30%, and puffiness was reduced by 35%. The compound base oil enhanced the formula's permeability and barrier repair effect, and the synergistic effect of microcapsule and liquid crystal technology achieved long-lasting sustained release.

[0031] Example 9 Based on Example 2, the microcirculation-promoting essential oil prepared in Example 2 based on carbonated hot spring extract was designated as Product A. The following method was used to test the microcirculation-promoting properties of Product A: Multiple groups of test subjects were recruited. All test subjects met the screening criteria of cold hands and feet or microcirculation disorders. They were asked to sit quietly for 30 minutes in a room with a constant temperature and humidity of 22±2℃ and 50±5% to acclimatize to the testing environment. Four testing areas (each 2cm × 2cm) were marked on the inner side of the test subjects' forearms. Area 1: No product applied, serving as a blank control; Area 2: Product B is a traditional blood-activating product. Product B contains capsaicin and plant essential oils, but does not contain carbonated hot spring ingredients. Area 3: Product C is selected. Product C is the microencapsulated extract of Product A, retaining only the base oil and liquid crystal forming agent.

[0032] Area 4: Select Product A; The product application rate in areas 2, 3 and 4 is 2 mg / cm². Before applying the product, the baseline blood flow value was measured using a laser Doppler flowmeter. After applying the product, the blood perfusion volume was continuously measured at 5 min, 15 min, 30 min, and 60 min. The average value was taken for each time point. The measurement results showed that Product A showed a peak blood flow improvement rate of 25±3% after 30 minutes of application, which was higher than that of traditional blood-activating products (Product B) by 15±2% and Product C (autologous matrix control) by 8±1%, while the blank control showed no significant change. Product A showed improvement lasting for more than 60 minutes, while the improvement of Product B lasted for 15-30 minutes before rapidly declining. The improvement rate of Product C (autologous matrix control) was consistently below 10%.

[0033] The results showed that the microencapsulation and liquid crystal technology of Product A ensured the slow release of CO2 and minerals, achieving a gentle and lasting promotion of microcirculation and avoiding short-term stimulation.

[0034] Example 10 Based on Example 2, the microcirculation-promoting essential oil prepared in Example 2 based on carbonated hot spring extract was designated as Product A. The transdermal behavior of active ingredients in Product A was tested using the following method: Test group: Product A (complete formulation, containing microencapsulated extract and liquid crystal forming agent) was selected. Control group: Product B was selected. Product B is a simple blend of essential oils (all active ingredients, such as carbonated spring water and anti-aging units, are directly mixed in meadowfoam seed oil without microencapsulation or liquid crystal structure). Using 0.5 mm thick artificial skin or excised pig skin as a barrier, the artificial skin or excised pig skin was fixed in a Franz diffusion cell with an effective diffusion area of ​​1.0 cm² and a receiving chamber volume of 5 mL. The receiving solution in the diffusion cell was a phosphate buffer solution with a pH of 7.4, and the temperature was kept constant at 37 °C.

[0035] 0.5g of sample was evenly applied to the barrier surface, and the receiving liquid was sampled at 1h, 2h, 4h, 6h and 8h. The CO2 release and 3-O-ethyl ascorbic acid concentration in the receiving liquid were detected by gas chromatography and HPLC. The structure was examined and it was found that: The cumulative permeation curves of CO2 and 3-O-ethyl ascorbic acid in Product A are flat and continuously rising, with total permeation amounts of 15.2 μg / cm² and 12.5 μg / cm² after 8 hours, respectively, indicating that the liquid crystal structure achieves programmed sustained release.

[0036] Product B, a blend of essential oils, exhibited a burst of release within the first 2 hours (penetration rate reaching 8 μg / cm²), but the penetration rate decreased significantly in the later stages, with the total penetration rate after 8 hours being only 60% of that of Product A. The results showed that Product A's delivery system was more efficient, avoided waste of active ingredients, extended the duration of action, and optimized the sustained release and transdermal absorption of active ingredients.

[0037] Example 11 Based on Example 2, the microcirculation-promoting essential oil prepared in Example 2 based on carbonated hot spring extract was designated as Product A. The stability and activity preservation of Product A were tested using the following methods: Test group: Product A; Control group 1: Product B was selected. Product B is a formula without liquid crystal forming agent (other ingredients are the same as product A, but the lecithin-cetyl alcohol complex is removed and meadowfoam seed oil is increased to 65%). Control group 2: Product C was selected. Product C was a formula with half the antioxidant (vitamin E content was reduced to 0.6%, while other ingredients were the same as product A). Products A, B, and C were placed in a constant temperature chamber at 40℃ and 75% relative humidity and stored for 3 months. Simultaneously, a thermal cycling test was conducted (-10℃ to 40℃, 10 cycles every 24 hours). The appearance of products A, B, and C was observed for stratification, precipitation, and discoloration. Then, the CO2 residue rate and 3-O-ethyl ascorbic acid content were detected by infrared spectroscopy and HPLC, and the retention rate was calculated. Finally, the appearance changes and active ingredient retention rates of products A, B, and C were compared.

[0038] The comparison results show that: Product A showed no stratification, precipitation, or discoloration after accelerated testing, with a CO2 residue rate of over 85% and a 3-O-ethyl ascorbic acid retention rate of over 90%.

[0039] Product B exhibited slight oil separation and precipitation, with CO2 residue dropping to 70% and active ingredient retention rate at only 75%. Product C showed no stratification, but the 3-O-ethyl ascorbic acid retention rate dropped to 80%, indicating that insufficient antioxidants led to degradation.

[0040] The results show that liquid crystal forming agents and antioxidants play a key role in maintaining formulation stability and active ingredient efficacy, and have a synergistic stabilizing effect.

[0041] Comparative Example 1 Based on Example 2, the microcirculation-promoting essential oil based on carbonated hot spring extract prepared in Example 2 was designated as Product A. Simultaneously, the liquid crystal forming agent in the preparation components of Product A was removed, and the content of meadowfoam seed oil was increased to 65%. The microcirculation-promoting essential oil based on carbonated hot spring extract was then prepared again using the same method as Product A, resulting in Product B. Product B had a pH of 6.5 and a CO2 sustained-release time of 2 hours. In vitro skin model testing of Product B revealed that, compared to Product A, the transdermal absorption rate of Product B was reduced by 50%, the barrier repair effect was not significant, and slight stratification occurred in the accelerated stability test.

[0042] Therefore, it can be seen that the liquid crystal structure is the core to ensure the sustained release and transdermal absorption of active ingredients, and its absence will lead to a significant decrease in efficacy.

[0043] Comparative Example 2 Based on Example 2, the microcirculation-promoting essential oil prepared in Example 2 based on carbonated hot spring extract was designated as Product A, and a traditional essential oil was designated as Product B. Product B contained only plant essential oil base oil (80% meadowfoam seed oil) and a fragrance revitalizing matrix (2% rose essential oil and rosemary essential oil combined), without microcapsule extracts, liquid crystal forming agents, anti-aging units, or advanced penetration enhancers. The preparation method was simple mixing and stirring, without any special processes.

[0044] A comparison of the effects of product A and product B revealed that, compared to product A, product B resulted in a 5% decrease in facial microcirculation blood flow perfusion, no increase in collagen density, and a deficiency in carbon dioxide and minerals, thus failing to address the root causes of skin problems.

[0045] The working principle of this invention is as follows: The microcirculation-promoting essential oil based on carbonated hot spring extract proposed in this application integrates key components of the carbonated hot spring extract that promote microcirculation through microencapsulation, accelerating the removal of metabolic waste and enhancing the skin's self-repair ability. Then, a liquid crystal forming agent is introduced to spontaneously form a layered structure on the skin, mimicking the skin's lipid barrier, encapsulating carbon dioxide and mineral ions from the carbonated spring, ensuring the long-term stable existence of active ingredients in the essential oil matrix, avoiding volatilization and inactivation, optimizing the sustained release and transdermal absorption of active ingredients, allowing them to reach the dermis layer to promote increased capillary blood flow, promote skin metabolism, improve dull skin tone and local tissue fluid accumulation caused by poor circulation. Moreover, it promotes increased capillary blood flow in a gentle and lasting manner, producing a gentle warming sensation, improving user comfort, and ensuring the bioavailability and targeted action efficiency of subsequent anti-aging, brightening, and other active ingredients.

[0046] The above description is merely a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in the present invention, based on the technical solution and inventive concept of the present invention, should be covered within the scope of protection of the present invention.

Claims

1. A microcirculation promoting essential oil based on a carbonated hot spring extract, characterized in that, The components include the following mass contents: carbonated hot spring extract 10%-30%, plant essential oil base oil 50%-70%, liquid crystal forming agent 4%-7%, fragrance revitalizing matrix 1%-3%, anti-aging lightening unit 1%-2%, tip penetration enhancer 0.1%-0.5%, antioxidant 0.5%-2%, wherein the carbonated hot spring extract is a microencapsulated carbonated spring liquid containing dissolved carbon dioxide gas and calcium, magnesium, sodium mineral ions, and the encapsulation wall material is a gelatin-arabic gum composite wall material; the liquid crystal forming agent is a complex of lecithin and cetyl alcohol at a weight ratio of 2:

1.

2. A microcirculation promoting essential oil based on carbonated spa extract according to claim 1, characterized in that, The plant essential oil base oil is a complex of one or more of white pool seed oil, squalane and jojoba oil, and the unsaturated fatty acid content is greater than or equal to 80%.

3. A microcirculation promoting essential oil based on carbonated spa extract according to claim 1, characterized in that, The fragrance revitalizing matrix is a mixture of rose essential oil and rosemary essential oil at a weight ratio of 1:

1.

4. A microcirculation promoting essential oil based on carbonated spa extract according to claim 1, characterized in that, The anti-aging lightening unit is a mixture of bakuchiol and 3-O-ethyl ascorbic acid at a weight ratio of 1:

1.

5. A microcirculation promoting essential oil based on carbonated spa extract according to claim 1, characterized in that, The tip penetration enhancer is a peptide amino acid surfactant.

6. A microcirculation promoting essential oil based on carbonated spa extract according to claim 1, characterized in that, The carbon dioxide concentration in the microencapsulated carbonated hot spring extract is greater than or equal to 1000 ppm, the total mineral content is 1.5-2.5 g / L, and the pH value is 5.0-5.

8.

7. A method for preparing a microcirculation promoting essential oil based on carbonated mineral spring extract according to any one of claims 1-6, characterized in that, The method comprises the following steps: Step one, collect natural carbonated hot spring water, filter out impurities through a 0.22 μm microporous filter membrane to obtain carbonated spring liquid; Step two, mix the carbonated spring liquid with the gelatin-arabic gum composite wall material at a mass ratio of 1:1, and homogenize and stir at 45-50°C and a stirring rate of 5000 rpm for 10-15 min to form an emulsion, then prepare microcapsules by spray drying to obtain microencapsulated carbonated hot spring extract powder; Step three, select a plant essential oil base oil with an unsaturated fatty acid content of not less than 80%, purify it by molecular distillation at 90-100°C and a vacuum degree of less than or equal to 10 Pa to remove impurities and odors, and obtain the pretreated plant essential oil base oil; Step four, mix 10%-30% microencapsulated carbonated hot spring extract powder, 50%-70% pretreated plant essential oil base oil, 4%-7% liquid crystal forming agent, 1%-3% fragrance revitalizing matrix, 1%-2% anti-aging lightening unit, 0.1%-0.5% tip penetration enhancer, and 0.5%-2% antioxidant vitamin E according to the weight percentage, and homogenize and emulsify at 25-30°C and a stirring rate of 10000-12000 rpm for 10-15 min to obtain an essence oil mixture; Step five, in a sterile environment, filter the essence oil mixture through a 0.22 μm microporous filter membrane, then fill it into a pre-sterilized brown glass bottle by nitrogen filling and seal it to prevent oxidation of active ingredients; Step six, randomly select the filled finished product for testing to ensure that the pH value, viscosity, stability and microbial indicators of the finished product meet the quality standards.

8. A method of preparing a microcirculation promoting essential oil based on carbonated spring extract according to claim 7, characterized in that, The encapsulation efficiency of the carbonated hot spring extract microcapsule powder in step two is greater than or equal to 90%.

9. The method for preparing a microcirculation-promoting essential oil based on carbonated hot spring extract according to claim 7, characterized in that, The filling environment temperature of the essential oil mixture in the step five is 20-25℃, and the temperature-sensitive active substance is added when the base oil is cooled to <40℃.

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