A pesticide synergist and its preparation method

Abstract

This invention discloses a pesticide synergist and its preparation method. The synergist is composed of 7-9 parts potassium oleate, 1-2 parts dipotassium hydrogen phosphate, and 1-2 parts 2-hydroxy-4-methylvaleric acid in a specific mass ratio. The preparation method involves stirring and mixing the above components at room temperature until completely dissolved to form a homogeneous solution. This synergist can be used in combination with chemical pesticides such as triadimefon, carbendazim, and pyraclostrobin. By enhancing the adhesion, penetration, and binding efficiency of pesticides to plant surfaces and pathogen targets, it can maintain over 90% control efficacy even with a 50%-80% reduction in chemical pesticide usage, significantly reducing pesticide residues and environmental risks. The raw materials are readily available, the process is simple, and the cost is low, making it suitable for large-scale production and of great significance for achieving reduced pesticide use and increased efficiency in agriculture and sustainable development.

Description

Technical Field

[0001] This invention relates to the field of pesticide technology, and in particular to a pesticide synergist and its preparation method. Background Technology

[0002] Fungal diseases are very common plant diseases, affecting staple crops, fruit trees, and flowers. In recent years, fungal diseases have continued to cause damage in various planting areas of my country, becoming a major disease for many plants. These diseases can cause infection of leaves and roots in mild cases, and death of the entire plant in severe cases, seriously affecting crop growth and yield, and causing significant agricultural economic losses.

[0003] Currently, the main methods for controlling fungal diseases include chemical control using fungicides, biological control using biocontrol microorganisms, breeding disease-resistant varieties, and strengthening field management. However, due to the lack of crop varieties with comprehensive resistance to fungal diseases, the most urgent need remains to continuously control disease occurrence using economical and effective methods. Therefore, despite the significant negative impacts of chemical pesticide control on the ecological environment and biological survival, such as pesticide residues, environmental pollution, and increased pathogen resistance, it is still widely used globally due to its low cost and rapid effectiveness.

[0004] However, this also presents a problem: the control of fungal diseases requires the application of large amounts of chemical pesticides, which inevitably leads to pesticide residues, affecting grain quality and safety, and ultimately threatening human health. Therefore, how to significantly reduce the use of chemical pesticides while ensuring control effectiveness has become a key technical issue that urgently needs to be addressed to maintain safe agricultural production and food safety.

[0005] While some existing pesticide synergist technologies can improve efficacy to a certain extent, they often suffer from limited synergistic effects, high costs, or poor environmental compatibility, making it difficult to maintain high control efficacy while achieving significant reductions in pesticide use.

[0006] Therefore, developing a highly efficient, low-cost, and environmentally friendly pesticide synergist is of great significance for promoting the sustainable development of agriculture. Summary of the Invention

[0007] The purpose of this invention is to provide a pesticide synergist that is highly efficient, low-cost, and environmentally friendly.

[0008] To achieve the above objectives, the present invention adopts the following technical solution:

[0009] In a first aspect of the present invention, a pesticide synergist is provided, the pesticide synergist comprising, by weight parts:

[0010] Potassium oleate 7-9 parts, dipotassium hydrogen phosphate 1-2 parts, 2-hydroxy-4-methylvaleric acid 1-2 parts.

[0011] Furthermore, the pesticide synergist comprises, by weight parts:

[0012] Potassium oleate 6 parts, dipotassium hydrogen phosphate 1.5 parts, 2-hydroxy-4-methylvaleric acid 1.5 parts.

[0013] In a second aspect of the invention, a method for preparing the aforementioned pesticide synergist is provided, the method comprising:

[0014] Potassium oleate, dipotassium hydrogen phosphate, and 2-hydroxy-4-methylvaleric acid were mixed in proportion and stirred at room temperature until completely dissolved to form a homogeneous solution.

[0015] Furthermore, the stirring is carried out under normal pressure and at 20-30°C for 30-60 minutes.

[0016] In a third aspect of the invention, the application of the aforementioned pesticide synergist in enhancing the control of plant fungal diseases by chemical pesticides is provided.

[0017] Furthermore, the chemical pesticide includes at least one of triadimefon, carbendazim, and pyraclostrobin.

[0018] Furthermore, when the synergist is combined with chemical pesticides, the amount of chemical pesticides used can be reduced by 50%-80%.

[0019] In a fourth aspect of the invention, a pesticide is provided comprising the pesticide synergist as described in claim 1 or 2, and a chemical pesticide.

[0020] One or more technical solutions in the embodiments of the present invention have at least the following technical effects or advantages:

[0021] The pesticide synergist and its application provided by this invention, through comparison of experimental data from examples and comparative examples, demonstrate the following significant technical effects:

[0022] 1. Excellent pesticide reduction effect: As shown in Examples 1 and 2, this synergist, when combined with triadimefon and carbendazim, can achieve a 75% (0.5% → 0.12%) and 80% (0.05% → 0.01%) reduction in pesticide dosage, respectively. Example 3 shows that when combined with azoxystrobin, a 50% (0.02% → 0.01%) reduction can be achieved. This significantly reduces the direct use of chemical pesticides.

[0023] 2. Stable and excellent efficacy: While achieving a significant reduction in pesticide use, the control effect is not diminished; in fact, in most cases, it is comparable to or slightly improved compared to the conventional dosage. For example, the control efficacy of a 75% reduced dose of triadimefon plus a synergist reached 92.1%, superior to the 90.8% of the conventional dosage of triadimefon; the control efficacy of an 80% reduced dose of carbendazim plus a synergist was 90.2%, comparable to the 89.6% of the conventional dosage of carbendazim. This indicates that this synergist can effectively maintain or even enhance the biological activity of pesticides.

[0024] 3. Environmentally friendly and highly safe: Due to the significant reduction in the use of chemical pesticides, the amount of pesticide residues in crops and the environment is reduced from the source, which helps to improve the quality and safety of agricultural products, reduce the risks to the environment and non-target organisms, and meet the development needs of green agriculture.

[0025] 4. Strong synergistic effect: This synergist shows significant synergistic effects on three different chemical pesticides (triazole, benzimidazole, and methoxyacrylate) with different mechanisms of action (triadimefon, carbendazim, and pyraclostrobin), indicating that it has broad application potential.

[0026] 5. Simple and economical preparation process: The preparation method of this synergist only requires mixing and stirring at room temperature, without the need for complex equipment or harsh conditions, and the cost is low, making it very suitable for large-scale industrial production. Attached Figure Description

[0027] To more clearly illustrate the technical solutions in the embodiments of the present invention, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0028] Figure 1 The diagram shows a comparison of the effects of using 0.12% triadimefon combined with the synergist of this invention and using 0.5% triadimefon at the conventional dosage in controlling tobacco powdery mildew after 14 days, as shown in Experiment Example 1.

[0029] Figure 2 The image shows a comparison of the effects of using 0.01% carbendazim combined with the synergist of this invention and using 0.05% carbendazim at the conventional dosage in controlling powdery mildew of pumpkin 14 days after Experiment Example 2. Detailed Implementation

[0030] The present invention will be described in detail below with reference to specific embodiments and examples, thereby making the advantages and various effects of the present invention more clearly apparent. Those skilled in the art should understand that these specific embodiments and examples are for illustrative purposes only and are not intended to limit the present invention.

[0031] Throughout this specification, unless otherwise specified, the terminology used herein should be understood as having the meaning commonly used in the art. Therefore, unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In the event of any conflict, this specification shall prevail.

[0032] Unless otherwise specified, all raw materials, reagents, instruments and equipment used in this invention can be obtained by purchasing them from the market or by existing methods.

[0033] The following will provide a detailed description of a pesticide synergist of this application, in conjunction with embodiments, comparative examples, and experimental data.

[0034] Example 1: Preparation of the pesticide synergist of the present invention

[0035] Weigh out 6 kg of potassium oleate, 1.5 kg of dipotassium hydrogen phosphate, and 1.5 kg of 2-hydroxy-4-methylvaleric acid, place them in a mixing container, and stir at room temperature (25°C) for 45 minutes until all components are completely dissolved to form a homogeneous and transparent solution, which is the pesticide synergist described in this invention.

[0036] Example 2: Preparation of the pesticide synergist of the present invention

[0037] Weigh 7 kg of potassium oleate, 2 kg of dipotassium hydrogen phosphate, and 2 kg of 2-hydroxy-4-methylvaleric acid, place them in a mixing container, and stir at room temperature (25°C) for 45 minutes until all components are completely dissolved to form a homogeneous and transparent solution, which is the pesticide synergist described in this invention.

[0038] Example 3: Preparation of the pesticide synergist of the present invention

[0039] Weigh out 9 kg of potassium oleate, 1 kg of dipotassium hydrogen phosphate, and 1 kg of 2-hydroxy-4-methylvaleric acid, place them in a mixing container, and stir at room temperature (25°C) for 45 minutes until all components are completely dissolved to form a homogeneous and transparent solution, which is the pesticide synergist described in this invention.

[0040] Application Example 1: The pesticide synergist of this invention, combined with triadimefon, is used to control tobacco powdery mildew.

[0041] 1. Experimental Design:

[0042] Experimental group: 0.12% triadimefon + synergist prepared in Example 1.

[0043] Comparative Example 1: 0.5% triadimefon (normal dosage control group).

[0044] Comparative Example 2: The synergist prepared in Example 1 was used alone (without pesticides).

[0045] Blank control: Water treatment.

[0046] 2. Test methods:

[0047] Foliar spraying was performed at the early stage of tobacco powdery mildew. The disease index was investigated 14 days after application, and the relative control efficacy was calculated. The results are shown in the table below.

[0048] 3. Test Results

[0049] Table 1: Efficacy of triadimefon in the control of tobacco powdery mildew

[0050]

[0051] From Table 1 and Figure 1 It is evident that, compared to the conventional dosage of triadimefon (Comparative Example 1), the experimental group, even with a 75% reduction in triadimefon dosage, achieved a slightly higher control efficacy (92.1%) than the conventional dosage group (90.8%). The synergist alone (Comparative Example 2) showed almost no control effect, indicating that it does not possess fungicidal activity itself; its core function lies in significantly enhancing the efficacy of the pesticide.

[0052] Application Example 2: The pesticide synergist of this invention, combined with carbendazim, is used to control powdery mildew in pumpkins.

[0053] 1. Experimental Design:

[0054] Experimental group: 0.01% carbendazim + synergist prepared in Example 1.

[0055] Comparative Example 3: 0.05% carbendazim (conventional dosage control group).

[0056] Comparative Example 2 and the blank control are the same as in Example 2.

[0057] 2. Test methods:

[0058] Foliar spraying was applied to pumpkin at the early stage of powdery mildew. The disease index was investigated 14 days after application, and the relative control efficacy was calculated. The results are shown in the table below.

[0059] 3. Experimental Results:

[0060] Table 2: Effect of carbendazim compound treatment on powdery mildew control in pumpkin

[0061]

[0062] From Table 2 and Figure 2 It can be seen that after the experimental group reduced the dosage of carbendazim by 80%, its control efficacy (90.2%) was comparable to that of the conventional dosage group (89.6%), which once again proves the excellent effect of the synergist of this invention in significantly reducing the amount of pesticides used.

[0063] Application Example 3: The pesticide synergist of this invention, combined with azoxystrobin, is used to control wheat rust.

[0064] 1. Experimental Design:

[0065] Experimental group: 0.01% azoxystrobin + synergist prepared in Example 1.

[0066] Comparative Example 4: 0.02% azoxystrobin (conventional dosage control group).

[0067] Comparative Example 2 and the blank control are the same as those in the aforementioned examples.

[0068] 2. Test methods:

[0069] Foliar spraying was performed at the early stage of wheat rust disease. The disease index was investigated 14 days after application, and the relative control efficacy was calculated. The results are shown in the table below.

[0070] 3. Experimental Results:

[0071] Table 3: Efficacy of azoxystrobin compound in controlling wheat rust

[0072]

[0073] As shown in Table 3, after reducing the dosage of azoxystrobin by 50%, the control efficacy (89.6%) in the experimental group was comparable to or even slightly improved compared to the conventional dosage group (88.5%). This indicates that the synergist of this invention has a universal synergistic effect on different types of chemical pesticides (triazoles, benzimidazoles, and methoxyacrylates).

[0074] By comparing the above embodiments with the comparative examples, we can conclude that:

[0075] (1) Excellent pesticide reduction effect: The synergist of this invention, when combined with triadimefon, carbendazim and pyraclostrobin, can achieve pesticide reduction of 75%, 80% and 50% respectively, with a huge reduction in pesticide dosage.

[0076] (2) Stable control effect: While the amount of pesticides was greatly reduced, the control effect of each experimental group (all exceeding 90% or equivalent to the conventional dosage) did not decrease, fully meeting the control needs in agricultural production.

[0077] (3) Strong versatility: This synergist has shown significant synergistic effects on a variety of chemical pesticides with different mechanisms of action and has a wide range of applications.

[0078] (4) Environmentally friendly: By significantly reducing the amount of chemical pesticides used, pesticide residues and environmental risks can be effectively reduced from the source, which is in line with the development direction of green agriculture.

[0079] Experimental Example 1: Validation Experiment of the Synergistic Effect of the Synergist of the Invention (Taking Triadimefon Compound as an Example)

[0080] 1. Experimental objective:

[0081] The purpose of this study is to verify whether the combination of the three components (potassium oleate, dipotassium hydrogen phosphate, and 2-hydroxy-4-methylvaleric acid) in the synergist of this invention produces a synergistic effect, rather than a simple additive effect.

[0082] 2. Experimental Design:

[0083] All treatment groups used a 75% reduction in triadimefon (0.12%) as a base, with different combinations of adjuvants added for comparison.

[0084] Experimental group (this invention): 0.12% triadimefon + 6 parts potassium oleate + 1.5 parts dipotassium hydrogen phosphate + 1.5 parts 2-hydroxy-4-methylvaleric acid (complete formula).

[0085] Comparative Example 5: 0.12% triadimefon + potassium oleate alone (9 parts, with the upper limit of its mass parts being equivalent to the total mass).

[0086] Comparative Example 6: 0.12% triazolone + 2-hydroxy-4-methylvaleric acid alone (2 parts, maximum by weight).

[0087] Comparative Example 7: 0.12% triadimefon + 6 parts potassium oleate + 1.5 parts dipotassium hydrogen phosphate (lacking 2-hydroxy-4-methylpentanoic acid).

[0088] Comparative Example 8: 0.12% triadimefon + 6 parts potassium oleate + 1.5 parts 2-hydroxy-4-methylvaleric acid (lacking dipotassium hydrogen phosphate).

[0089] Comparative Example 9: 0.12% triadimefon + 1.5 parts dipotassium hydrogen phosphate + 1.5 parts 2-hydroxy-4-methylvaleric acid (potassium oleate was missing).

[0090] Comparative Example 1 (Baseline): 0.5% triadimefon (normal dosage).

[0091] Blank control: Water treatment.

[0092] 3. Experimental Results and Analysis:

[0093] The table below shows the control effect on tobacco powdery mildew 14 days after application.

[0094] Table 4: Effects of different combinations of synergists on the efficacy of triadimefon

[0095]

[0096] 4. Summary of Experimental Examples:

[0097] From the data in Table 4 and Figure 1The following key conclusions can be drawn from the trend:

[0098] Synergistic effect confirmed: The efficacy of the experimental group (three-component complete formulation) (92.1%) was far higher than that of any single component (comparative examples 5 and 6). This indicates that the three components worked together to produce a synergistic effect, rather than a simple additive effect.

[0099] The indispensability of each component: The absence of any one of the three components significantly reduces the efficacy. This indicates that potassium oleate (surface activity and penetration), dipotassium hydrogen phosphate (nutrient and pH regulation), and 2-hydroxy-4-methylvaleric acid (target binding enhancement) all play irreplaceable roles in the system, together forming the core of the synergistic effect.

[0100] Finally, it should be noted that the terms “comprising,” “including,” or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0101] Although preferred embodiments of the invention have been described, those skilled in the art, upon learning the basic inventive concept, can make other changes and modifications to these embodiments. Therefore, the appended claims are intended to be interpreted as including both the preferred embodiments and all changes and modifications falling within the scope of the invention.

[0102] Obviously, those skilled in the art can make various modifications and variations to this invention without departing from its spirit and scope. Therefore, if these modifications and variations fall within the scope of the claims of this invention and their equivalents, this invention also intends to include these modifications and variations.

Claims

1. The application of pesticide synergists in enhancing the control of plant fungal diseases by chemical pesticides, characterized in that, The pesticide synergist comprises, by weight parts: The chemical pesticide comprises 7-9 parts potassium oleate, 1-2 parts dipotassium hydrogen phosphate, and 1-2 parts 2-hydroxy-4-methylvaleric acid, and includes at least one of triadimefon, carbendazim, and pyraclostrobin.

2. The application of pesticide synergists in enhancing the control of plant fungal diseases by chemical pesticides, characterized in that, The pesticide synergist comprises, by weight, 6 parts potassium oleate, 1.5 parts dipotassium hydrogen phosphate, and 1.5 parts 2-hydroxy-4-methylvaleric acid, and the chemical pesticide includes at least one of triadimefon, carbendazim, and pyraclostrobin.

3. The application according to any one of claims 1 or 2, characterized in that, The preparation method of the pesticide synergist includes: mixing potassium oleate, dipotassium hydrogen phosphate and 2-hydroxy-4-methylvaleric acid in a certain proportion, stirring at room temperature until completely dissolved to form a homogeneous solution.

4. The application according to claim 3, characterized in that, The stirring is carried out under normal pressure and at 20-30℃ for 30-60 minutes.

5. The application according to claim 1 or 2, characterized in that, When the pesticide synergist is combined with the chemical pesticide, the amount of chemical pesticide used is reduced by 50%-80%.

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