Pesticide composition containing chlorine indole hydrazide and application thereof

Abstract

The invention relates to a pesticide composition containing chlorine indole hydrazide and application of the pesticide composition, and belongs to the technical field of pesticide compositions. The active ingredients in the composition are chloroindole hydrazide and propineb, wherein the weight ratio of chloroindole hydrazide to propineb is (1: 50)-(50: 1). According to the pesticide composition provided by the invention, the chloroindole hydrazide and the propineb are mixed according to a specific proportion, and the compounded chloroindole hydrazide and propineb have an obvious synergistic effect, so that the application effect is obviously superior to the sum of theoretical effects of a single agent, the harm of virus diseases can be better controlled, and the activity of the virus diseases is greatly reduced.

Description

Technical Field

[0001] This invention relates to the technical field of pesticide compositions, and more specifically to a pesticide composition containing chlorine indolehydrazine and its application. Background Technology

[0002] Plant viral diseases are caused by plant viruses and are the second most common plant diseases, often referred to as "plant cancer." Severe outbreaks can significantly impact plant growth and yield, even leading to total crop failure. Plant viral diseases typically manifest in four forms: mosaic, yellowing, necrosis, and malformation. They are primarily transmitted through seeds or by piercing-sucking insects such as thrips, aphids, broad mites, and whiteflies.

[0003] Chloroindolehydrazine is a novel compound developed based on tetrahydrocarbylhydrazine compounds. It can activate the antioxidant system and salicylic acid pathway in plants, exhibiting some control efficacy against diseases such as powdery mildew, Fusarium head blight, and downy mildew. Preliminary trials have demonstrated its effectiveness against tomato mosaic virus, pepper malformation virus, and melon shrunkenness virus. The structural formula of chloroindolehydrazine is as follows: .

[0004] Propineb is a long-lasting, fast-acting, broad-spectrum protective fungicide. Its mechanism of action primarily involves acting on the cell wall and protein synthesis of fungi and inhibiting the oxidation of pyruvate within the pathogen, thereby suppressing spore infection and germination, as well as mycelial growth. Preliminary experiments have demonstrated its good control effect against viral diseases. Furthermore, this fungicide contains zinc, which is easily absorbed by crops, and can inactivate viruses, reduce viral activity, and slow down viral replication in plant cells. The structural formula of propineb is as follows: .

[0005] Chlorindolehydrazine (CDIH) exhibits good control efficacy against crop viral diseases such as tomato mosaic virus, pepper malformation virus, and melon wrinkle virus. However, its effectiveness is limited against other crop viral diseases, such as wheat dwarf virus and rice stripe mosaic virus. To address the limitations of existing single-agent pesticides in controlling crop viral diseases, including narrow control spectrum and poor efficacy, and to further expand the agricultural application of CDIH, the development of highly effective, broad-spectrum, and less likely to induce resistance-related viral disease control agents has become a pressing technical challenge in the field of agricultural plant protection. Surprisingly, the inventors discovered in batch experiments that the combination of CDIH and propineb exhibits a significant synergistic effect. Summary of the Invention

[0006] To address the problems of narrow control spectrum and poor efficacy against some plant viruses when using existing single-agent chloroindolehydrazine, this invention provides a pesticide composition containing chloroindolehydrazine and its application to solve the above problems.

[0007] The technical solution of this invention is as follows: In a first aspect, the present invention provides a pesticide composition containing chlorindolehydrazine, wherein the active ingredients in the composition are chlorindolehydrazine and propineb, wherein the weight ratio of chlorindolehydrazine to propineb is 1:50 to 50:1.

[0008] As a more preferred embodiment, the weight ratio of chloroindolehydrazine and propineb in the pesticide composition is 1:10 to 10:1.

[0009] As a more preferred embodiment, the weight ratio of chloroindolehydrazine and propineb in the pesticide composition is 1:4 to 3:1.

[0010] As the most preferred embodiment, the weight ratio of chloroindolehydrazine to propineb is 1~2:2~1.

[0011] In a preferred embodiment, the active ingredients chloroindolehydrazine and propineb account for 1% to 90% of the total weight of the pesticide composition.

[0012] As a more preferred embodiment, the active ingredients chloroindolehydrazine and propineb account for 15% to 70% of the total weight of the pesticide composition.

[0013] As a preferred embodiment, the formulation of the composition for preventing and controlling plant viral diseases is a suspension concentrate, water-dispersible granules, wettable powder, granules, dispersible oil suspension, or microcapsule suspension.

[0014] As a more preferred embodiment, the pesticide composition is in the form of a suspension or a microcapsule suspension.

[0015] In addition to the active ingredient, the pesticide composition also includes agriculturally acceptable adjuvants, such as one or more of the following: dispersants, wetting agents, thickeners, defoamers, antifreeze agents, emulsifiers, disintegrants, preservatives, stabilizers, penetrants, solvents, and carriers.

[0016] in, Dispersants can be: sodium lignosulfonate, sodium polyphosphate, sodium methylene bis(thalassium)sulfonate, alkylphenol polyoxyethylene ether, nonylphenol polyoxyethylene ether, polyoxyethylene polyoxypropylene ether block copolymer, sodium lauryl polyoxyethylene ether sulfate, alkylnaphthalene formaldehyde condensate sulfonate, alkyl polyoxyethylene ether sulfonate, sodium alkylnaphthalene sulfonic acid condensate, alkylphenol polyoxyethylene ether, polyacrylic acid, phosphates, polycarboxylate, etc.

[0017] Wetting agents can be: dodecyl phosphate, sodium butylnaphthalene sulfonate, dodecylbenzene sulfonate, polysulfonate, polyvinyl alcohol, polythiol, polycarboxylate, sodium alkylphenol polyoxyethylene ether sulfate, fatty alcohol polyoxyethylene ether, fatty acid polyoxyethylene ester, phenol sulfonate formaldehyde condensate, glycerin, pyridine, separating powder, tea seed cake, soapberry powder, etc.

[0018] Thickeners can include: sodium polyacrylate, coconut oil diethanolamide, xanthan gum, sodium chloride, potassium chloride, ammonium chloride, methylcellulose gum arabic, sodium alginate, magnesium aluminum silicate, lauryl alcohol, and carboxymethyl cellulose, etc.

[0019] Defoamers can be: silicone oil, polydimethylsiloxane, alumina, silica, C10. C20 saturated fatty acid compounds, silicates, sulfonates, etc.

[0020] Antifreeze agents can include: ethylene glycol, propylene glycol, isopropanol, n-butanol, vegetable oil, vegetable oil derivatives, and mineral oil, etc.

[0021] Emulsifiers can include: sodium dodecyl sulfate, sodium stearate, sodium carboxymethyl cellulose, fatty alcohol polyoxyethylene ether, polysorbate, phenethylphenol polyoxyethylene ether polyoxypropylene ether, diphenylethyl biphenol polyoxyethylene ether, lauryl alcohol polyoxyethylene ether, glyceryl monostearate, lecithin, lanolin, beeswax, gum arabic, diglycerol, alkylphenol formaldehyde resin polyoxyethylene ether, rosin acid polyoxyethyl dithiophosphate, and fatty acid esters, etc.

[0022] Disintegrants can include: aluminum chloride, sodium chloride, ammonium chloride, sodium sulfate, ammonium sulfate, urea, sodium carbonate, sodium bicarbonate, bentonite, glucose, sucrose, starch, cellulose, etc.

[0023] Preservatives can include sodium benzoate, calcium benzoate, etc.

[0024] Stabilizers can be: epoxidized vegetable oil, 2,6 Di-tert-butyl-p-cresol, triethanolamine oleate, disodium hydrogen phosphate, oxalic acid, succinic acid, adipic acid, borax, bentonite, attapulgite, talc, starch, etc. Penetrants can be: sodium dioctyl sulfosuccinate, menthol, clove volatile oil, sodium dioctyl maleate sulfonate, T-70, fatty alcohol polyoxyethylene ether, sodium butylnaphthalene sulfonate, sodium alkyl sulfate, etc.

[0025] Solvents can be: toluene, xylene, chlorobenzene, methanol, methyl sulfoxide, water, ethanol, ethylene glycol, glycerol, pentanol, acetone, dimethylformamide, pyrrolidone, hydrocarbon carbonate, diesel, cyclohexanone, solvent oil, etc.

[0026] The carrier can be: bentonite, kaolin, calcium carbonate, precipitate, attapulgite, diatomaceous earth, etc.

[0027] Secondly, the present invention provides the application of a pesticide composition containing chlorindolehydrazine in the prevention and control of crop diseases, wherein the crop disease is a plant viral disease; and the crop is a chili pepper, tomato, wheat, rice or tobacco.

[0028] In a preferred embodiment, the viral disease is mosaic virus disease, streak virus disease, yellowing and curling leaf virus disease, leaf curling virus disease, or dwarf vine disease.

[0029] In a preferred embodiment, the crop is one of food crops, fruit trees, or vegetables.

[0030] In a preferred embodiment, the effective application rate of the pesticide composition is 60-120 g·ai / hm2 2 .

[0031] As a preferred embodiment, the pesticide composition is applied to the roots, stems, leaves, flowers, or fruits of plants by means of spraying, root irrigation, furrow application, or seed soaking.

[0032] The beneficial effects of this invention are as follows: The pesticide composition provided by this invention achieves a significant synergistic effect by compounding chlorindolehydrazine and propineb in a specific ratio. Its technical effect far exceeds the theoretical sum of the effects of using chlorindolehydrazine or propineb alone, solving the technical problem of limited efficacy of existing single pesticide formulations against viral diseases and difficulty in completely inhibiting viral activity. Specifically, this compound composition can more efficiently control viral diseases, significantly reducing viral activity. It not only improves the control effect and spectrum of viral diseases, reducing the incidence of diseased plants and the disease index, but also ensures crop yield and quality. Furthermore, compared to single formulations, it can reduce the dosage of active ingredients while achieving the same control effect, reducing pesticide usage, minimizing environmental pollution, delaying the development of viral resistance to single pesticides, extending pesticide lifespan, and reducing agricultural production costs. It has significant economic, ecological, and application prospects. Detailed Implementation

[0033] To enable those skilled in the art to better understand the technical solutions of this invention, the technical solutions in the embodiments of this invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of this invention, and not all embodiments. Based on the embodiments of this invention, all other embodiments obtained by those skilled in the art without creative effort should fall within the scope of protection of this invention.

[0034] The chloroindolehydrazine used in the examples was prepared in-house by Shandong Jingbo Agricultural Chemical Technology Co., Ltd. Propineb zinc and other auxiliaries and unlisted reagents were all commercially available substances.

[0035] Example 1 42% chloroindolehydrazine + propineb suspension (20:1) The suspension comprises the following components by weight percentage: 40% chloroindolehydrazine, 2% zinc propineb, 3% sodium polycarboxylate (dispersant), 2% sodium lignosulfonate (dispersant), 3% phenethylphenol polyoxyethylene ether (wetting agent), 0.12% xanthan gum (thickener), 1% magnesium aluminum silicate (thickener), 0.3% polydimethylsiloxane (defoamer), 3% ethylene glycol (antifreeze agent), and deionized water to make up to 100%.

[0036] Preparation method: According to the formulation ratio in the example, the active ingredients, dispersant, wetting agent, thickener, defoamer and antifreeze are placed in the reaction vessel, water is added and mixed evenly, and then subjected to high-speed shearing, wet sand milling and finally homogenization filtration to obtain 42% chloroindolehydrazine + propineb suspension.

[0037] Example 2 44% chloroindolehydrazine + propineb suspension (10:1) The suspension comprises the following components by weight percentage: 40% chloroindolehydrazine, 4% zinc propineb, 3% sodium polycarboxylate (dispersant), 2% sodium lignosulfonate (dispersant), 3% phenethylphenol polyoxyethylene ether (wetting agent), 0.12% xanthan gum (thickener), 1% magnesium aluminum silicate (thickener), 0.3% polydimethylsiloxane (defoamer), 3% ethylene glycol (antifreeze agent), and deionized water to make up to 100%.

[0038] The preparation method is the same as in Example 1.

[0039] Example 3 54% chloroindolehydrazine + propineb suspension (5:1) The suspension comprises the following components by weight percentage: chloroindolehydrazine 45%, zinc propineb 9%, sodium polycarboxylate (dispersant) 3%, sodium lignosulfonate (dispersant) 2%, phenethylphenol polyoxyethylene ether (wetting agent) 3%, xanthan gum (thickener) 0.12%, magnesium aluminum silicate (thickener) 1%, polydimethylsiloxane (defoamer) 0.3%, ethylene glycol (antifreeze agent) 3%, and deionized water to make up to 100%.

[0040] The preparation method is the same as in Example 1.

[0041] Example 4 40% chloroindolehydrazine + propineb suspension (4:1) The suspension comprises the following components by weight percentage: chloroindolehydrazine 32%, zinc propineb 8%, sodium polycarboxylate (dispersant) 3%, sodium lignosulfonate (dispersant) 2%, phenethylphenol polyoxyethylene ether (wetting agent) 3%, xanthan gum (thickener) 0.12%, magnesium aluminum silicate (thickener) 1%, polydimethylsiloxane (defoamer) 0.3%, ethylene glycol (antifreeze agent) 3%, and deionized water to make up to 100%.

[0042] The preparation method is the same as in Example 1.

[0043] Example 5 32% chloroindolehydrazine + propineb suspension (3:1) The suspension comprises the following components by weight percentage: 24% chloroindolehydrazine, 8% zinc propineb, 3% sodium polycarboxylate (dispersant), 2% sodium lignosulfonate (dispersant), 3% phenethylphenol polyoxyethylene ether (wetting agent), 0.12% xanthan gum (thickener), 1% magnesium aluminum silicate (thickener), 0.3% polydimethylsiloxane (defoamer), 3% ethylene glycol (antifreeze agent), and deionized water to make up to 100%.

[0044] The preparation method is the same as in Example 1.

[0045] Example 6 30% chloroindolehydrazine + propineb suspension (2:1) The suspension comprises the following components by weight percentage: 20% chloroindolehydrazine, 10% zinc propineb, 3% sodium polycarboxylate (dispersant), 2% sodium lignosulfonate (dispersant), 3% phenethylphenol polyoxyethylene ether (wetting agent), 0.12% xanthan gum (thickener), 1% magnesium aluminum silicate (thickener), 0.3% polydimethylsiloxane (defoamer), 3% ethylene glycol (antifreeze agent), and deionized water to make up to 100%.

[0046] The preparation method is the same as in Example 1.

[0047] Example 7 20% chloroindolehydrazine + propineb suspension (1:1) The suspension comprises the following components by weight percentage: 10% indolehydrazine chlorohydrin, 10% zinc propineb, 3% sodium polycarboxylate (dispersant), 2% sodium lignosulfonate (dispersant), 3% phenethylphenol polyoxyethylene ether (wetting agent), 0.12% xanthan gum (thickener), 1% magnesium aluminum silicate (thickener), 0.3% polydimethylsiloxane (defoamer), 3% ethylene glycol (antifreeze agent), and deionized water to make up to 100%.

[0048] The preparation method is the same as in Example 1.

[0049] Example 8 30% chloroindolehydrazine + propineb suspension (1:2) The suspension comprises the following components by weight percentage: 10% chloroindolehydrazine, 20% zinc propineb, 3% sodium polycarboxylate (dispersant), 2% sodium lignosulfonate (dispersant), 3% phenethylphenol polyoxyethylene ether (wetting agent), 0.12% xanthan gum (thickener), 1% magnesium aluminum silicate (thickener), 0.3% polydimethylsiloxane (defoamer), 3% ethylene glycol (antifreeze agent), and deionized water to make up to 100%.

[0050] The preparation method is the same as in Example 1.

[0051] Example 9 32% chloroindolehydrazine + propineb suspension (1:3) The suspension comprises the following components by weight percentage: 8% chloroindolehydrazine, 24% zinc propineb, 3% sodium polycarboxylate (dispersant), 2% sodium lignosulfonate (dispersant), 3% phenethylphenol polyoxyethylene ether (wetting agent), 0.12% xanthan gum (thickener), 1% magnesium aluminum silicate (thickener), 0.3% polydimethylsiloxane (defoamer), 3% ethylene glycol (antifreeze agent), and deionized water to make up to 100%.

[0052] The preparation method is the same as in Example 1.

[0053] Example 10 40% chloroindolehydrazine + propineb suspension (1:4) The suspension comprises the following components by weight percentage: 8% chloroindolehydrazine, 32% zinc propineb, 3% sodium polycarboxylate (dispersant), 2% sodium lignosulfonate (dispersant), 3% phenethylphenol polyoxyethylene ether (wetting agent), 0.12% xanthan gum (thickener), 1% magnesium aluminum silicate (thickener), 0.3% polydimethylsiloxane (defoamer), 3% ethylene glycol (antifreeze agent), and deionized water to make up to 100%.

[0054] The preparation method is the same as in Example 1.

[0055] Example 11 54% chloroindolehydrazine + propineb suspension (1:5) The suspension comprises the following components by weight percentage: chloroindolehydrazine 9%, zinc propineb 45%, sodium polycarboxylate (dispersant) 3%, sodium lignosulfonate (dispersant) 2%, phenethylphenol polyoxyethylene ether (wetting agent) 3%, xanthan gum (thickener) 0.12%, magnesium aluminum silicate (thickener) 1%, polydimethylsiloxane (defoamer) 0.3%, ethylene glycol (antifreeze agent) 3%, and deionized water to make up to 100%.

[0056] The preparation method is the same as in Example 1.

[0057] Example 12 44% chloroindolehydrazine + propineb suspension (1:10) The suspension comprises the following components by weight percentage: 4% chloroindolehydrazine, 40% zinc propineb, 3% sodium polycarboxylate (dispersant), 2% sodium lignosulfonate (dispersant), 3% phenethylphenol polyoxyethylene ether (wetting agent), 0.12% xanthan gum (thickener), 1% magnesium aluminum silicate (thickener), 0.3% polydimethylsiloxane (defoamer), 3% ethylene glycol (antifreeze agent), and deionized water to make up to 100%.

[0058] The preparation method is the same as in Example 1.

[0059] Example 13 42% chloroindolehydrazine + propineb suspension (1:20) The suspension comprises the following components by weight percentage: 2% chloroindolehydrazine, 40% zinc propineb, 3% sodium polycarboxylate (dispersant), 2% sodium lignosulfonate (dispersant), 3% phenethylphenol polyoxyethylene ether (wetting agent), 0.12% xanthan gum (thickener), 1% magnesium aluminum silicate (thickener), 0.3% polydimethylsiloxane (defoamer), 3% ethylene glycol (antifreeze agent), and deionized water to make up to 100%.

[0060] The preparation method is the same as in Example 1.

[0061] Example 14 30% Chloroindolehydrazine suspension The suspension comprises the following components by weight percentage: 30% chloroindolehydrazine, 3% sodium polycarboxylate (dispersant), 2% sodium lignosulfonate (dispersant), 3% phenethylphenol polyoxyethylene ether (wetting agent), 0.12% xanthan gum (thickener), 1% magnesium aluminum silicate (thickener), 0.3% polydimethylsiloxane (defoamer), 3% ethylene glycol (antifreeze agent), and deionized water to make up to 100%.

[0062] The preparation method is the same as in Example 1.

[0063] Example 15 30% Propineb suspension The suspension comprises the following components by weight percentage: 30% zinc propineb, 3% sodium polycarboxylate (dispersant), 2% sodium lignosulfonate (dispersant), 3% phenethylphenol polyoxyethylene ether (wetting agent), 0.12% xanthan gum (thickener), 1% magnesium aluminum silicate (thickener), 0.3% polydimethylsiloxane (defoamer), 3% ethylene glycol (antifreeze agent), and deionized water to make up to 100%.

[0064] The preparation method is the same as in Example 1.

[0065] Test case The following test cases illustrate the investigation methods, data analysis, and statistical methods used before and after drug treatment: Five points are randomly selected from each area, and six plants are checked at each point. If there are fewer than 30 plants in a protected area, the entire area should be investigated. The investigation should be conducted by plant and graded, including the total number of plants and the number of diseased plants at each grade.

[0066] Note: During each efficacy survey, observe whether any pesticide damage (such as burns, wilting, leaf drop, flower drop, fruit drop, poor growth, and leaf deformities) occurs in each treated area.

[0067] The disease grading standards are as follows: Level 0: No symptoms; Grade 1: Heart-shaped leaves with prominent veins or lightly variegated leaves; Grade 3: Mottled foliage on the heart and middle leaves, sometimes with necrotic spots on the leaves; Level 5: Most leaves are mosaic, a few leaves are deformed or wrinkled, sometimes necrotic spots appear on the leaves or neck, or short streaks appear on the neck; Level 7: Most leaves are deformed and thin, or the stems and leaf veins show systematic necrosis, and the plant is stunted; Level 9: The plant has severe systemic mosaic and deformities, or sometimes severe systemic necrosis, and the plant is significantly stunted or even dies.

[0068] Method for calculating the severity of illness: ; .

[0069] The method for determining whether two active ingredients have a synergistic effect is as follows: The theoretical efficacy of the compound formulation is calculated based on the actual control effect of a single agent: E0 = [X a +X b (X a ×X b ÷100)]×100%.

[0070] in: X a The control effect (%) of a single agent of chloroindolehydrazine.

[0071] X b The control efficacy (%) of a single application of propineb.

[0072] E0 represents the theoretical prevention and control effect (%) of the compound formulation.

[0073] E represents the actual efficacy of chloroindolehydrazine and propineb mixed in the above proportions.

[0074] Evaluation criteria: E-E0 > 10% indicates a synergistic effect; E-E0 < -10% indicates an antagonistic effect; E-E0 between ±10% indicates an additive effect.

[0075] Test Example 1 Field trials of pepper mosaic virus disease Experiment location: Pangjia Rural Revitalization Industrial Park, Binzhou City, Shandong Province.

[0076] Experimental Methods: Each treatment was set up with three replicates, with 30 plants per replicate. The pesticide was applied during the seedling stage of peppers. The disease index of pepper mosaic virus was investigated 15 days after application, and the control effect was then calculated. In this experiment, the symptoms of pepper virus disease on the stems and leaves after pesticide application were investigated and graded, mainly focusing on various symptoms such as fern-like leaves, mosaic patterns, vein separation, dwarfing, yellowing, necrosis, terminal bud dieback, and malformation. The pepper virus disease index (or disease severity index) was then calculated, and the control effect was statistically analyzed. Specific pesticide concentrations and the control effect on pepper virus disease are shown in Table 1 below. No phytotoxicity was observed in any of the examples 15 days after application.

[0077] Table 1 - Inhibition results of various drug treatments on pepper virus disease

[0078] The comparison between the actual and theoretical control effects of pepper virus disease in Table 1 shows that the combination of chlorindolehydrazine and propineb in a weight ratio of 3:1 to 1:4 has a synergistic effect on the control of pepper virus disease.

[0079] Test Example 2 Field trials of tomato yellow leafroll virus disease Experiment location: Pangjia Rural Revitalization Industrial Park, Binzhou City, Shandong Province.

[0080] Experimental Methods: Each treatment was set up with three replicates, with 30 plants per replicate. The application period was during the tomato seedling stage. Fifteen days after application, the disease index of tomato yellowing and leaf curl virus was investigated, and the control effect was calculated. In this experiment, the symptoms of tomato viral diseases were investigated and graded after application, mainly focusing on various symptoms such as fern-like leaves, mosaic patterns, vein clearing, dwarfing, yellowing, necrosis, terminal bud dieback, and malformation. The tomato viral disease index (or disease severity index) was then calculated, and the control effect was statistically analyzed. Specific application concentrations and the control effects on tomato viral diseases are shown in Table 2 below. No phytotoxicity was observed in any of the examples 15 days after application.

[0081] Table 2 - Inhibition results of various pesticide treatments on tomato viral diseases

[0082] The comparison between the actual and theoretical control effects of tomato virus diseases in Table 2 shows that the combination of chlorindolehydrazine and propineb in a weight ratio of 3:1 to 1:4 has a synergistic effect on the control of tomato virus diseases.

[0083] Test Example 3 Field trials of wheat dwarf disease Experiment location: Pangjia Rural Revitalization Industrial Park, Binzhou City, Shandong Province.

[0084] Experimental Methods: Each treatment was set up with three replicates, with 30 plants per replicate. The application period was during the wheat seedling stage. The disease index of wheat dwarf disease was investigated 15 days after application, and the control effect was calculated. In this experiment, the viral symptoms of wheat dwarf disease after application were investigated and graded, mainly focusing on various symptoms such as mosaic, dwarfing, yellowing, necrosis, and terminal dieback. The wheat dwarf disease index (or disease severity index) was then calculated, and the control effect was statistically analyzed. Specific application concentrations and control effects on wheat dwarf disease are shown in Table 3 below. No phytotoxicity was observed in any of the examples 15 days after application.

[0085] Table 3 - Inhibition results of various pesticide treatments on wheat dwarf disease

[0086] The comparison between the actual and theoretical control effects of wheat dwarf disease in Table 3 shows that the combination of chlorindolehydrazine and propineb in a weight ratio of 3:1 to 1:4 has a synergistic effect on the control of wheat dwarf disease.

[0087] Test Example 4 Field trials of rice stripe mosaic virus Experiment location: Rice-growing area of ​​Yiyang City, Hunan Province.

[0088] Experimental Methods: Each treatment was set up with three replicates, each with 30 plants. The pesticide was applied during the rice seedling stage. Fifteen days after application, the disease index of rice stripe mosaic virus was investigated, and the control effect on rice stripe mosaic virus was calculated. In this experiment, the symptoms of rice stripe mosaic virus after pesticide application were investigated and graded, mainly focusing on various symptoms such as mosaic, stunting, yellowing, necrosis, and top dieback. The rice stripe mosaic virus index (or disease index) was then calculated, and the control effect was statistically analyzed. Specific pesticide concentrations and the control effect on rice stripe mosaic virus are shown in Table 4 below. No phytotoxicity was observed in any of the examples 15 days after application.

[0089] Table 4 - Inhibition results of various pesticide treatments on rice stripe mosaic virus

[0090] The comparison between the actual and theoretical control effects of rice stripe mosaic disease in Table 4 shows that the combination of chlorindolehydrazine and propineb in a weight ratio of 3:1 to 1:4 has a synergistic effect on the control of rice stripe mosaic disease.

[0091] Test Example 5 Test Examples 1-4 verified, using the Gowing method, that the combined use of chlorindolehydrazine and propineb exhibited a synergistic effect against pepper viral diseases, tomato viral diseases, wheat dwarf disease, and rice stripe mosaic disease within a certain proportion range. To further verify the synergistic effect of chlorindolehydrazine and propineb, field efficacy trials were conducted on chlorindolehydrazine alone, propineb alone, and combinations of chlorindolehydrazine and propineb against pepper viral diseases, tomato viral diseases, wheat dwarf disease, and rice stripe mosaic disease, with consistent dosages of the active ingredients in each treatment.

[0092] Experiment location: The field efficacy trials for pepper virus disease, tomato virus disease, and wheat dwarf disease were conducted at Pangjia Rural Revitalization Industrial Park in Binzhou City, Shandong Province.

[0093] The field efficacy test for rice stripe mosaic virus was conducted in rice-growing areas of Yiyang City, Hunan Province.

[0094] Experimental Methods: Field efficacy experiments for pepper virus diseases, tomato virus diseases, wheat dwarf virus, and rice stripe mosaic virus were conducted, referring to Application Examples 1-4 except for the dosage of the active ingredient in each treatment. Specific application concentrations and control effects on rice stripe mosaic virus are shown in Table 5 below. No phytotoxicity was observed in any of the examples 15 days after application.

[0095] Table 5 - Inhibition results of various pesticide treatments on different plant viral diseases

[0096] By comparing the actual control effects of each agent on pepper virus disease, tomato virus disease, wheat dwarf disease, and rice stripe mosaic disease when the effective ingredients are the same (60 g / ha) in Table 5, it can be seen that when chlorindolehydrazine is combined with propineb in a weight ratio of 3:1 to 1:4, it is superior to chlorindolehydrazine or propineb alone in controlling pepper virus disease, tomato virus disease, wheat dwarf disease, and rice stripe mosaic disease.

[0097] Although the present invention has been described in detail by way of preferred embodiments, the present invention is not limited thereto. Various equivalent modifications or substitutions can be made to the embodiments of the present invention by those skilled in the art without departing from the spirit and essence of the invention, and such modifications or substitutions should all be within the scope of the present invention. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in the present invention should also be covered within the protection scope of the present invention.

Claims

1. A pesticide composition containing chlorindolehydrazine, characterized in that, The active ingredients in the composition are chloroindolehydrazine and propineb, wherein the weight ratio of chloroindolehydrazine to propineb is 1:50 to 50:

1.

2. The pesticide composition containing chlorinated indolehydrazine as described in claim 1, characterized in that, The weight ratio of chlorindolehydrazine and propineb in the pesticide composition is 1:10 to 10:

1.

3. The pesticide composition containing chlorinated indolehydrazine as described in claim 1, characterized in that, The weight ratio of chlorindolehydrazine and propineb in the pesticide composition is 1:4 to 3:

1.

4. A pesticide composition containing chlorinated indolehydrazine as described in any one of claims 1-3, characterized in that, The weight ratio of chloroindolehydrazine to propineb is 1~2:1~1.

5. The pesticide composition containing chlorinated indolehydrazine as described in claim 4, characterized in that, The active ingredients, chloroindolehydrazine and propineb, account for 1% to 90% of the total weight of the pesticide composition.

6. The pesticide composition containing chlorinated indolehydrazine as described in claim 5, characterized in that, The active ingredients, chloroindolehydrazine and propineb, account for 15% to 70% of the total weight of the pesticide composition.

7. The pesticide composition containing chlorinated indolehydrazine as described in claim 1, characterized in that, The formulation of the composition for preventing and controlling plant viral diseases is a suspension concentrate, water-dispersible granules, wettable powder, granules, dispersible oil suspension, or microcapsule suspension.

8. The application of a pesticide composition containing chlorinated indolehydrazine as described in claim 1 in the control of crop diseases, characterized in that, The crop disease is a plant viral disease; the crop is a chili pepper, tomato, wheat, rice, or tobacco.

9. The application as described in claim 8, characterized in that, The viral diseases mentioned are mosaic virus disease, streak virus disease, yellowing and curling leaf virus disease, leaf curling virus disease, or dwarfism.

10. The application as described in claim 8, characterized in that, The effective application rate of the pesticide composition is 60-120 g ai / hm. 2 .

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