Porous structure
By introducing lattice unit structures into the porous structure, combining large and small pores, the problem of balancing nutrient delivery and cell adhesion is solved, improving bone ingrowth and structural stability, and reducing surgical trauma and costs.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2023-06-15
- Publication Date
- 2026-04-10
AI Technical Summary
Existing porous structure designs cannot simultaneously address nutrient delivery and cell adhesion functions, resulting in bone graft chamber designs that are highly invasive, costly, and have poor fusion outcomes.
The lattice unit structure is adopted, combined with the design of large-aperture and small-aperture channels, which are used for nutrient transport and cell attachment and growth, respectively. Primary and secondary channels are set on the surface of the lattice unit structure and between adjacent structures, with pore sizes ranging from 300-1500μm and 100-300μm, respectively.
It achieves the dual functions of nutrient delivery and cell adhesion, improves bone ingrowth, enhances the stability of porous structures, and reduces surgical trauma and costs.
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Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the field of orthopedics, in particular to a porous structure. BACKGROUND
[0002] Orthopedic implants have been developed for many years and have become mature. Traditional orthopedic implants, especially spinal products, are basically provided with bone grafting bins. The size of the bone grafting bin determines the early bone growth area. If the bone grafting bin is too large, the contact area between the orthopedic implant and the vertebrae is too small, which can cause the orthopedic implant to loosen, collapse, and not fuse, thereby causing economic burden to the patient.
[0003] The porous structure part of the conventional porous structure orthopedic implant is usually arranged in a regular lattice. The regular lattice is usually a regular tetrahedron, a hexahedron or other polyhedral structure. The bone grafting bin is usually a hollow region passing through the center of the orthopedic implant. The porous structure design in the prior art cannot meet the two functional requirements of nutrient transport and cell adhesion. These two functional requirements correspond to different pore size ranges. The porous structure in the prior art does not combine the porous structure units that meet the two pore size ranges together to form a full range of bone growth channels.
[0004] In bone grafting surgery, doctors need to extract autologous bone or use allogeneic bone grafting materials. Extracting autologous bone can cause greater trauma to the patient, and using allogeneic bone can cause additional costs, higher surgical costs, and cancellation of the bone grafting bin can simplify the surgical procedure, reduce the operation time, reduce the probability of surgical errors, and reduce the risk of intraoperative infection.
[0005] The present application relates to a porous structure that can replace the bone grafting bin design, which has a large pore size and a small pore size combined structure with nutrient transport and cell adhesion functions. SUMMARY
[0006] The purpose of the present application is to provide a porous structure to replace the bone grafting bin design in the prior art orthopedic implant, and to solve the technical problem that the porous structure cannot meet the nutrient transport and cell adhesion functions.
[0007] The embodiment of the present application is implemented as follows: the present application provides a porous structure, which comprises: a lattice unit structure;
[0008] The lattice unit structure is provided with a plurality of lattice unit structures arranged in order. The lattice unit structure has a first pore for nutrient transport and waste discharge. The surface of the lattice unit structure and any four adjacent lattice unit structures are provided with a second pore, and the second pore is used for cell adhesion and growth.
[0009] Further, the second pore includes a primary pore and a secondary pore.
[0010] The primary pore is located on the surface of the lattice unit structure, and the secondary pore is between any four adjacent lattice unit structures.
[0011] Further, the first pore has a pore size ranging from 300 to 1500 μm, and the second pore has a pore size ranging from 100 to 300 μm.
[0012] Further, the lattice unit structure is a hexadecahedron, a dodecahedron, a diamond configuration or other porous structure.
[0013] Further, the first pore is an octagonal, decagonal or polygonal structure in the transverse cross section and longitudinal cross section of the lattice unit structure.
[0014] Further, the primary pore is a quadrilateral, pentagonal, hexagonal, octagonal or polygonal structure.
[0015] Further, the surface of the connecting rod structure is provided with a particle structure having a diameter ranging from 1 to 1000 nanometers.
[0016] As described above, the present application has the following advantages:
[0017] The present application provides a porous structure, which comprises a lattice unit structure; each lattice unit structure has a first pore for nutrient substance transmission, waste discharge and cell adhesion and growth; a second pore is arranged on the surface of each lattice unit structure and between any four adjacent lattice unit structures, and the second pore is used for cell adhesion and growth; the arranged lattice unit structures have a bone space maintaining ability, each lattice unit structure is provided with a convex structure, which is beneficial to increase friction and improve the stability of the porous structure. The first pore and the second pore can provide micro-flow field medium transmission capacity required by blood supply, and the first pore and the second pore are more conducive to the flow of tissue fluid, promote the formation of capillary network in the lattice unit structure, provide necessary blood supply for bone growth, and solve the technical problems that the bone growth effect is poor and the structure is difficult to maintain stable for a long time under external load in the prior art. BRIEF DESCRIPTION OF DRAWINGS
[0018] Figure 1 FIG. 1 is a schematic diagram of the overall structure of an intervertebral fusion cage according to an embodiment of the present application;
[0019] Figure 2 FIG. 2 is a front view of the overall structure of the intervertebral fusion cage according to an embodiment of the present application;
[0020] Figure 3 FIG. 3 is a top view of the overall structure of the intervertebral fusion cage according to an embodiment of the present application;
[0021] Figure 4 This is another schematic diagram of the overall structure of the interbody fusion device in one embodiment of the present invention;
[0022] The reference numerals in the attached figures are as follows: 1. Crystal unit structure; 2. First channel; 3. Second channel; 4. Primary channel; 5. Secondary channel. Detailed Implementation
[0023] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.
[0024] See Figures 1 to 4 According to the present invention, the porous structure includes a lattice unit structure 1; a first channel 2; a second channel 3; a primary channel 4; and a secondary channel 5.
[0025] See Figures 1 to 4 The porous structure region is composed of multiple orderly arranged lattice unit structures 1. The lattice unit structures 1 are hexahedral, dodecahedral, diamond-shaped, or other porous structures, and are connected by rod-like structures. Each face of the lattice unit structure 1 has rod-like protrusions. This structural design provides initial stability during product implantation, large-aperture channels for nutrient transport and waste removal in the blood, and multiple small-aperture channels for cell attachment and growth.
[0026] The aperture range of the first channel 2 is 300-1500μm; the aperture range of the second channel 3 is 100-300μm.
[0027] The first channel 2 is formed by connecting the surface linkage structure of the lattice unit structure 1, and has a quadrilateral, pentagonal, hexagonal, octagonal, decagonal or polygonal structure. The structure of the first channel 2 has a large aperture, which can provide enough space for blood delivery and nutrient delivery, and at the same time provide sufficient space for the small aperture primary channel 4, realizing the protruding structure design of the primary channel 4.
[0028] The primary channel 4 has a quadrilateral, pentagonal, hexagonal, octagonal, or polygonal structure.
[0029] The beneficial effects of this invention are:
[0030] This invention proposes a porous structure combining large and small pore sizes, which can replace traditional bone graft chamber structures and can be applied to all major orthopedic fields related to bone integration, such as joint, spine, trauma, and sports medicine. The porous structure combining large and small pore sizes can simultaneously achieve blood and nutrient delivery and cell adhesion and growth, resulting in better bone ingrowth, effectively increasing the bone fusion area, reducing the product's elastic modulus, and alleviating surgical trauma and financial burden for patients.
[0031] Those skilled in the art will understand that the features described in the various embodiments and / or claims of this disclosure can be combined and / or combined in various ways, even if such combinations or combinations are not explicitly described in this application. In particular, without departing from the spirit and teachings of this application, the features described in the various embodiments and / or claims of this application can be combined and / or combined in various ways, and all such combinations and / or combinations fall within the scope of this application.
[0032] This document uses specific embodiments to illustrate the principles and implementation methods of the present invention. The descriptions of these embodiments are merely illustrative of the method and core concepts of the present invention and are not intended to limit this application. Those skilled in the art can make changes to the specific implementation methods and application scope based on the ideas, spirit, and principles of the present invention. Any modifications, equivalent substitutions, or improvements made should be included within the scope of protection of this application.
Claims
1. A porous structure, characterized in that, include: Crystal unit cell structure; The lattice unit structure is provided in multiple ways, and the multiple lattice unit structures are arranged in an orderly manner; The surface of the lattice unit structure has a first channel that facilitates nutrient transport, waste removal, and cell attachment and growth; a second channel is provided between the surface of the lattice unit structure and between any four adjacent lattice unit structures, and the second channel is used for cell attachment and growth.
2. The porous structure as described in claim 1, characterized in that, The second channel includes a primary channel and a secondary channel; the primary channel is located on the surface of the lattice unit structure, and the secondary channel is located between any four adjacent lattice unit structures.
3. The porous structure as described in claim 2, characterized in that, The pore size of the first channel ranges from 300 to 1500 μm; the pore size of the second channel ranges from 100 to 300 μm.
4. The porous structure as described in claim 3, characterized in that, The lattice unit structure is hexahedral, dodecahedral, diamond configuration, or other porous structure.
5. The porous structure as described in claim 4, characterized in that, The first channel is formed by connecting the surface linkage structure of the lattice unit structure, and is in the form of a quadrilateral, pentagon, hexagon, octagon, decagon or polygon structure.
6. The porous structure as described in claim 5, characterized in that, The primary channel has a quadrilateral, pentagonal, hexagonal, octagonal, or polygonal structure.
7. The porous structure as described in claim 6, characterized in that, The surface of the connecting rod structure is provided with a granular structure, the diameter of which ranges from 1 to 1000 nanometers.