Anti-bubble dispensing device for protein-containing drugs

Abstract

The invention discloses an anti-bubble dispensing device for protein-containing drugs, relates to the technical field of anti-bubble dispensing, and provides the following scheme that the anti-bubble dispensing device comprises a dispensing tank, a driving motor is arranged at the top of the dispensing tank, and a partition plate is fixedly installed on the upper portion of the interior of the dispensing tank; and a liquid separation plate is fixedly mounted on the inner wall of the dispensing tank and located below the partition plate. The liquid distribution plate is trumpet-shaped and provided with holes, medicine can be preliminarily dispersed, the liquid guide plate is matched with the liquid distribution plate, the electric push rod drives the liquid distribution plate to move up and down, the falling state of the medicine is changed, the medicine slowly flows along the tank wall, the bubble generation probability is reduced, the vacuum pump creates a low-air-pressure environment to further inhibit bubbles, and the quality and convenience are improved. The driving motor drives the stirring component to fully mix medicine, quality is guaranteed, the assembly in the supporting frame drives the defoaming teeth to conduct defoaming at different heights according to liquid level signals, the PLC is connected with all the components, automatic control is achieved, and operation convenience is greatly improved.

Description

Technical Field

[0001] This invention relates to the field of anti-bubble dispensing technology, and more specifically to an anti-bubble dispensing device for protein-containing drugs. Background Technology

[0002] In the preparation of protein-containing drugs, due to the special properties of protein solutions, bubbles are easily generated during stirring and mixing. The presence of bubbles not only affects the appearance quality of the drug, but more importantly, it negatively impacts the stability and efficacy of the drug. For example, bubbles may alter the microstructure of proteins, affecting their biological activity and thus reducing the therapeutic effect of the drug. Moreover, bubbles may also cause a series of problems in subsequent filling and storage processes, such as leading to inaccurate drug dosage. Therefore, there is an urgent need for a drug preparation device that can effectively prevent the generation of bubbles.

[0003] Most existing drug preparation devices are simple in structure and have limited functions, making it difficult to meet the requirements for preventing air bubbles when preparing protein-containing drugs. Some devices only have basic stirring functions, which cannot effectively control the generation of air bubbles during stirring, and may even introduce more air bubbles due to improper stirring methods. Although some devices have some anti-air bubble design, the design is not reasonable enough to effectively solve the problem of air bubbles affecting drug quality. Therefore, we propose an anti-air bubble preparation device for protein-containing drugs to solve the above problems. Summary of the Invention

[0004] In view of the deficiencies mentioned above in the background technology, a technical solution is provided for an anti-bubble dispensing device for protein-containing drugs.

[0005] It includes a dispensing tank, a drive motor is installed on the top of the dispensing tank, a partition is fixedly installed in the upper part of the inside of the dispensing tank, a liquid distribution plate is fixedly installed on the inner wall of the dispensing tank and below the partition, a liquid guide plate is installed below the liquid distribution plate, a support frame is installed inside the dispensing tank and below the liquid guide plate, a lifting plate is slidably connected in the frame of the support frame, multiple rows of defoaming teeth are evenly installed on the bottom surface of the lifting plate, a vacuum pump is installed on the left side of the dispensing tank, a vacuum tube is installed at the input end of the vacuum pump, and the other end of the vacuum tube passes through and extends into the inside of the dispensing tank.

[0006] In the above-mentioned technical solution for an anti-bubble dispensing device for protein-containing drugs, preferably: a mounting plate is fixedly installed on the right side of the top surface of the dispensing tank, and the drive motor is fixedly installed on the left side wall of the mounting plate.

[0007] Preferably, the top of the liquid guide plate is an upwardly convex arc shape, and a liquid baffle tube is fixedly installed at the center of the top of the liquid guide plate, and the edge of the liquid guide plate is inclined.

[0008] Preferably, the liquid distribution plate is funnel-shaped, the top of the liquid distribution plate has a through hole, and the inclined edge of the liquid guide plate matches the funnel shape of the liquid distribution plate.

[0009] Preferably, an electric push rod is fixedly installed on both sides of the top inner wall of the medicine dispensing tank, and the output end of the electric push rod is connected to a lifting rod through a coupling. The end of the lifting rod away from the electric push rod is fixedly connected to both sides of the top surface of the liquid guide plate.

[0010] Preferably, the output end of the drive motor is equipped with a rotating shaft that passes through the partition. The rotating shaft passes through the inside of the liquid-blocking pipe and extends to the lower part of the medicine tank. A rotating plate is installed at the bottom of the rotating shaft inside the medicine tank. Stirring rods are installed on both sides of the top surface of the rotating plate.

[0011] Preferably, an installation rod is fixedly installed on the right inner wall of the dispensing tank and below the liquid guide plate, and the support frame is fixedly installed on the end of the installation rod away from the inner wall of the dispensing tank.

[0012] Preferably, the inner walls on both sides of the support frame are equipped with electric slide rails, and electric slide blocks are provided on the electric slide rails. The electric slide blocks are connected to the two side walls of the lifting plate. Both the electric slide rails and the electric slide blocks are waterproof. A liquid level sensor is also installed at the bottom of the lifting plate.

[0013] Preferably, a support frame is fixedly installed on the left side wall of the dispensing tank, a mounting base is fixedly installed on the left side wall of the support frame, the vacuum pump is installed on the mounting base, a counterweight base is fixedly installed at the bottom of the support frame, and a PLC controller is also installed on the support frame, and the PLC controller is connected to the vacuum pump, drive motor, electric push rod and liquid level sensor.

[0014] Preferably, a dosing pipe is installed at an angle on the upper left side wall of the drug preparation tank, located between the partition and the dividing plate. The dosing pipe is equipped with a sealing cap. A discharge pipe is installed at the bottom of the drug preparation tank, and a valve is installed on the discharge pipe.

[0015] As can be seen from the above technical solution, the present invention provides an anti-bubble dispensing device for protein-containing drugs. Compared with the prior art, the present invention has the following beneficial effects:

[0016] 1. This anti-bubble dispensing device for protein-containing drugs features a funnel-shaped dispensing plate with a through-hole at the top for initial dispersion of the added drug. The top of the guide plate is an upward-convex arc shape with inclined edges that match the dispensing plate, further guiding the drug flow. An electric push rod moves the guide plate up and down via a lifting rod, changing the drug's falling state and allowing it to flow slowly down the inner wall of the dispensing tank, reducing the probability of bubble formation. Simultaneously, a vacuum pump extracts air from the dispensing tank through a vacuum tube, creating a low-pressure environment to further suppress bubble formation.

[0017] 2. This anti-foaming dispensing device for protein-containing drugs uses a drive motor to rotate a shaft, rotating plate, and stirring rod, achieving thorough mixing of the drugs in the tank and ensuring drug quality. An electric slide rail and electric slide block within the support frame move a lifting plate, allowing the defoaming teeth to defoam at different liquid levels based on signals from a liquid level sensor, thus improving the defoaming effect. A PLC controller is connected to the vacuum pump, drive motor, electric push rod, and liquid level sensor, enabling automated control and improving operational convenience. Attached Figure Description

[0018] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the accompanying drawings used in the description of the embodiments of the present invention or the prior art will be briefly introduced and explained below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a schematic diagram of the overall structure of an anti-bubble dispensing device for protein-containing drugs according to the present invention;

[0020] Figure 2 This is a cross-sectional view of the dispensing tank of an anti-bubble dispensing device for protein-containing drugs according to the present invention.

[0021] Figure 3 This is a cross-sectional view of the dispensing tank and partition of an anti-bubble dispensing device for protein-containing drugs according to the present invention.

[0022] Figure 4 This is a schematic diagram of the dispensing plate and the guiding plate of an anti-bubble dispensing device for protein-containing drugs according to the present invention;

[0023] Figure 5 This is a schematic diagram of the lifting plate and defoaming teeth structure of an anti-foaming dispensing device for protein-containing drugs according to the present invention.

[0024] Appendix Figure 1 - Appendix Figure 5The correspondence between the components is as follows:

[0025] In the diagram: 1. Dosing tank; 2. Discharge pipe; 3. Counterweight base; 4. Support frame; 5. Mounting base; 6. Vacuum pump; 7. Vacuum pipe; 8. Dosing pipe; 9. Drive motor; 10. Mounting plate; 11. Partition plate; 12. Separating plate; 13. Support frame; 14. Lifting plate; 15. Defoaming teeth; 16. Stirring rod; 17. Rotating plate; 18. Rotating shaft; 19. Liquid guide plate; 20. Electric push rod; 21. Liquid baffle pipe; 22. Lifting rod; 23. Mounting rod. Detailed Implementation

[0026] To enable those skilled in the art to better understand the present invention, the technical solution of the present invention will be described in further detail below with reference to the embodiments and accompanying drawings. Obviously, the described embodiments are merely some, not all, of the embodiments of the present invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative effort should fall within the scope of protection of the present invention.

[0027] It should be noted that, unless otherwise specified, the embodiments and features described in the present invention can be combined with each other. The present invention will now be described in detail with reference to the embodiments.

[0028] Example 1: Please refer to Figures 1-5 An anti-bubble dispensing device for protein-containing drugs includes a dispensing tank 1. When using the anti-bubble dispensing device for protein-containing drugs, first open the sealing cap on the dosing pipe 8, and add the raw material of the protein-containing drug into the dispensing tank 1 through the dosing pipe 8. The dosing pipe 8 is installed at an angle to facilitate the smooth flow of the drug into the tank. After the drug is added, close the sealing cap to ensure the airtightness of the tank.

[0029] During the dosing process through the dosing tube 8, the medicine first passes through the funnel-shaped dispensing plate 12. The top of the dispensing plate 12 has a through hole, which allows the medicine to fall evenly. The top of the guide plate 19 below it is an upward-convex arc shape, and the edge is inclined and matches the funnel shape of the dispensing plate 12, which can further guide the flow direction of the medicine. At the same time, the electric push rods 20 on both sides of the inner wall of the top of the dosing tank 1 are activated, and the lifting rod 22 connected by the coupling drives the guide plate 19 to move up and down, adjusting the speed of the medicine falling. Moreover, under the action of the guide plate 19, the medicine can flow into the dosing tank 1 along the inner wall of the dosing tank 1, which can reduce the generation of air bubbles during the dosing process.

[0030] Next, start the drive motor 9, which will make the drive motor 9 rotate at low speed. Since the drive motor 9 is fixedly installed on the left side wall of the mounting plate 10 on the right side of the top surface of the medicine tank 1, the rotating shaft 18 installed at its output end passes through the partition plate 11 and passes through the pipe of the baffle tube 21 at the top center of the liquid guide plate 19, extending to the lower part of the medicine tank 1. The stirring rod 16 on the rotating plate 17 installed at the bottom of the rotating shaft 18 starts to rotate, stirring and mixing the medicine in the tank.

[0031] When bubbles are generated during stirring, the electric slide rails on both sides of the inner wall of the support frame 13 are activated, driving the electric slide to move. Since the electric slide is connected to the side walls of the lifting plate 14, the lifting plate 14 slides within the support frame 13. Multiple rows of defoaming teeth 15 are evenly installed at the bottom of the lifting plate 14 to eliminate bubbles. In addition, the liquid level sensor installed at the bottom of the lifting plate 14 monitors the liquid level in real time and transmits the signal to the PLC controller installed on the support frame 4. The PLC controller controls the operation of the electric slide rails according to the liquid level, so that the lifting plate 14 is in the appropriate position for defoaming.

[0032] In addition, the vacuum pump 6 set on the left side of the drug preparation tank 1 is started, and the air inside the tank is extracted through the vacuum tube 7 to reduce the air pressure inside the tank and further reduce the generation of bubbles. After the drug preparation is completed, the sealing cover on the drug addition tube 8 can be opened to balance the air pressure inside the drug preparation tank 1. Then the valve on the drug discharge tube 2 at the bottom of the drug preparation tank 1 can be opened to discharge the prepared medicine.

[0033] Example 2: Please refer to Figures 1-5 When starting to prepare the medicine, the protein-containing medicine raw materials are added into the medicine preparation tank 1 through the medicine addition pipe 8 and the sealing cap is closed. First, the electric push rod 20 is controlled by the PLC controller to put the liquid guide plate 19 in a suitable position. Under the action of the liquid distribution plate 12 and in cooperation with the liquid distribution plate 12, the medicine can slowly flow into the interior of the medicine preparation tank 1 along the inner wall of the medicine preparation tank 1, so as to reduce the generation of bubbles in the initial stage.

[0034] The drive motor 9 is started, and the stirring rod 16 begins to stir. As stirring proceeds, when the liquid level sensor detects that the liquid level has risen to a certain level, it sends a signal to the PLC controller. The PLC controller controls the electric slide rail to start, causing the lifting plate 14 to descend. The defoaming teeth 15 are then immersed in the medicine to begin defoaming. During the defoaming action of the defoaming teeth 15, the vacuum pump 6 continues to work to maintain a low air pressure environment inside the medicine preparation tank 1, minimizing the generation of bubbles. After the medicine preparation is completed, the medicine is discharged through the discharge pipe 2.

[0035] Example 3: Please refer to Figures 1-5After adding the protein-containing drug raw materials to the mixing tank 1, the drive motor 9 is not started immediately. Instead, the vacuum pump 6 is turned on and the vacuum tube 7 is used to evacuate the inside of the mixing tank 1 to create a low-pressure environment and reduce the possibility of bubbles being generated during subsequent stirring.

[0036] After a period of vacuuming, the drive motor 9 is started, and the stirring rod 16 begins to stir the medicine. At this time, the PLC controller controls the electric push rod 20 according to the preset program, so that the liquid guide plate 19 moves up and down in a certain pattern, so that the medicine falls down the inner wall of the medicine tank 1, reducing the generation of bubbles. At the same time, the liquid level sensor monitors the liquid level in real time. When the liquid level reaches a suitable height, the PLC controller controls the electric slide rail to drive the lifting plate 14 down, and the defoaming teeth 15 begin to defoam.

[0037] During the stirring and defoaming process, the working status of the vacuum pump 6 can be adjusted at any time through the PLC controller, and the air pressure can be precisely controlled according to the actual situation inside the tank. After the medicine is prepared, the valve on the discharge pipe 2 is opened to discharge the medicine.

[0038] Implementation effect: The anti-bubble dispensing device uses a funnel-shaped liquid separator 12 with a through hole at the top to initially disperse the added medicine. The top of the liquid guide plate 19 is an upwardly convex arc shape with inclined edges that match the liquid separator 12, which can further guide the flow of medicine. The electric push rod 20 drives the liquid guide plate 19 to move up and down through the lifting rod 22, changing the falling state of the medicine and allowing the medicine to flow slowly down the inner wall of the dispensing tank 1, reducing the probability of bubble generation. At the same time, the vacuum pump 6 extracts air from the dispensing tank 1 through the vacuum tube 7 to create a low-pressure environment, further suppressing the generation of bubbles.

[0039] The drive motor 9 drives the rotating shaft 18, rotating plate 17, and stirring rod 16 to rotate, thereby achieving thorough mixing of the medicine in the tank and ensuring the quality of the medicine. The electric slide rail and electric slide seat in the support frame 13 drive the lifting plate 14 to move, so that the defoaming tooth 15 can perform defoaming at different liquid levels according to the signal fed back by the liquid level sensor, thereby improving the defoaming effect. The PLC controller is connected to the vacuum pump 6, drive motor 9, electric push rod 20, and liquid level sensor, which can realize automated control and improve the convenience of operation.

[0040] The above specific embodiments are merely explanations of the present invention and are not intended to limit the present invention. After reading this specification, those skilled in the art can make modifications to these embodiments without contributing any inventive step, but as long as they are within the scope of the claims of the present invention, they are protected by patent law.

Claims

1. A bubble-proof dispensing device for protein-containing drugs, comprising a dispensing tank (1), characterized in that: A drive motor (9) is provided on the top of the medicine preparation tank (1). A partition (11) is fixedly installed on the upper part of the inside of the medicine preparation tank (1). A liquid separating plate (12) is fixedly installed on the inner wall of the medicine preparation tank (1) and below the partition (11). A liquid guiding plate (19) is provided below the liquid separating plate (12). A support frame (13) is provided inside the medicine preparation tank (1) and below the liquid guiding plate (19). A lifting plate (14) is slidably connected inside the support frame (13). Multiple rows of defoaming teeth (15) are evenly installed on the bottom surface of the lifting plate (14). A vacuum pump (6) is provided on the left side of the medicine preparation tank (1). A vacuum tube (7) is installed at the input end of the vacuum pump (6). The other end of the vacuum tube (7) passes through and extends into the inside of the medicine preparation tank (1).

2. The anti-bubble dispensing device for protein-containing drugs according to claim 1, characterized in that: An installation plate (10) is fixedly installed on the right side of the top surface of the medicine dispensing tank (1), and the drive motor (9) is fixedly installed on the left side wall of the installation plate (10).

3. The anti-bubble dispensing device for protein-containing drugs according to claim 1, characterized in that: The top of the liquid guide plate (19) is an upwardly convex arc shape, and a liquid baffle (21) is fixedly installed at the center of the top of the liquid guide plate (19). The edge of the liquid guide plate (19) is inclined.

4. The anti-bubble dispensing device for protein-containing drugs according to claim 1, characterized in that: The liquid distribution plate (12) is funnel-shaped, and a through hole is provided at the top of the liquid distribution plate (12). The inclined edge of the liquid guide plate (19) matches the funnel shape of the liquid distribution plate (12).

5. The anti-bubble dispensing device for protein-containing drugs according to claim 1, characterized in that: Electric push rods (20) are fixedly installed on both sides of the top inner wall of the medicine dispensing tank (1). The output end of the electric push rod (20) is connected to a lifting rod (22) through a coupling. The end of the lifting rod (22) away from the electric push rod (20) is fixedly connected to both sides of the top surface of the liquid guide plate (19).

6. The anti-bubble dispensing device for protein-containing drugs according to claim 1, characterized in that: The output end of the drive motor (9) is equipped with a rotating shaft (18) that passes through the partition (11). The rotating shaft (18) passes through the inside of the baffle pipe (21) and extends to the lower part of the medicine tank (1). A rotating plate (17) is installed at the bottom of the rotating shaft (18) inside the medicine tank (1). Stirring rods (16) are installed on both sides of the top surface of the rotating plate (17).

7. The anti-bubble dispensing device for protein-containing drugs according to claim 1, characterized in that: An installation rod (23) is fixedly installed on the right inner wall of the medicine preparation tank (1) and below the liquid guide plate (19). The support frame (13) is fixedly installed at the end of the installation rod (23) away from the inner wall of the medicine preparation tank (1).

8. The anti-bubble dispensing device for protein-containing drugs according to claim 1, characterized in that: Electric slide rails are installed on both sides of the inner wall of the support frame (13), and electric slide blocks are provided on the electric slide rails. The electric slide blocks are connected to the two side walls of the lifting plate (14). Both the electric slide rails and the electric slide blocks are waterproof. A liquid level sensor is also installed at the bottom of the lifting plate (14).

9. A bubble-proof dispensing device for protein-containing drugs according to claim 1, characterized in that: A support frame (4) is fixedly installed on the left side wall of the medicine preparation tank (1). A mounting base (5) is fixedly installed on the left side wall of the support frame (4). The vacuum pump (6) is installed on the mounting base (5). A counterweight base (3) is fixedly installed at the bottom of the support frame (4). A PLC controller is also installed on the support frame (4). The PLC controller is connected to the vacuum pump (6), the drive motor (9), the electric push rod (20), and the liquid level sensor.

10. A bubble-proof dispensing device for protein-containing drugs according to claim 1, characterized in that: The dosing pipe (8) is installed at an incline on the upper left side wall of the dosing tank (1) between the partition plate (11) and the liquid separator (12). The dosing pipe (8) is equipped with a sealing cap. The bottom of the dosing tank (1) is equipped with a discharge pipe (2), and each discharge pipe (2) is equipped with a valve.

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