一种膨腹海马肽及其在制备抗疲劳制品中的应用

By discovering and preparing the highly bioactive DGGFVF peptide sequence of the bloated hippocampus, and embedding it into the Nrf2 active pocket to activate antioxidant enzymes, the problem of insufficient research on the anti-fatigue effects of the bloated hippocampus was solved, and significant anti-fatigue effects and muscle enhancement were achieved.

CN121949465BActive Publication Date: 2026-07-17OCEAN UNIV OF CHINA

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
OCEAN UNIV OF CHINA
Filing Date
2026-04-03
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing research on the activity of bloated hippocampus, especially in anti-fatigue applications, is limited. There is a need to explore more bloated hippocampus peptide resources that meet practical needs and satisfy new demands for technological development.

Method used

Research has revealed a highly bioactive bloated hippocampal peptide sequence, DGGFVF, which can embed into the active pocket of Nrf2, activate SOD and GSH-Px enzymes, reduce exercise-induced oxidative damage to skeletal muscle, and be used to prepare anti-fatigue products.

Benefits of technology

The expansion of hippocampal peptides significantly prolongs the time to exhaustion during weight-bearing swimming in experimental animals and enhances muscle strength, providing a new direction for the development of anti-fatigue products.

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Abstract

本发明涉及生物肽的制备与应用领域,尤其涉及一种膨腹海马肽及其在制备抗疲劳制品中的应用。本发明研究得到了1条具有高生物活性的活性肽序列,通过动物行为学实验验证了所述膨腹海马肽能够延长游泳力竭时间、增强肌肉力量,具有显著的抗疲劳效果,为海马抗疲劳制品开发提供了新的途径。
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