Hair growing and protecting method for improving scalp health and application of hair growing and protecting method

Abstract

The invention relates to the field of A61K8 / 18, in particular to a hair growing and protecting method for improving scalp health and application of the hair growing and protecting method, and the method is realized by preparing hair growing essence containing a hair growth promoting composition and enabling the hair growing essence to act on the scalp surface with health problems, and is applied to improving scalp health, treating alopecia and protecting and nourishing hair.

Description

Technical Field

[0001] This invention relates to the field of A61K8 / 18, specifically to a method for improving scalp health and promoting hair growth and its application. Background Technology

[0002] The scalp is covered by hair. Hair follicles and blood vessels are more abundant than other skin tissues, and the nerve distribution is also very dense. Blood vessels and lymphatic vessels located in the subcutaneous tissue supply nutrients and oxygen to the scalp, thus providing an environment for hair growth. However, harmful substances and waste excreted by the scalp mix with sebum and accumulate on the scalp surface, which can clog scalp pores, leading to scalp health problems, inducing inflammation, and even hair loss.

[0003] Currently, there are many treatments for hair loss, including topical medications, oral medications, health supplements, gene transplantation surgery, and hair transplantation surgery. However, these methods cannot effectively improve scalp health to achieve effective hair loss treatment and avoid minor side effects. Even minoxidil, which is approved by the FDA, may cause imbalances in the body, leading to side effects such as decreased sexual function, allergies, depression, and local inflammation. Chinese patent application CN108186531A discloses a hair growth essence and its preparation method and application. Specifically, it uses a variety of traditional Chinese medicines, including raw stemona root, arborvitae leaf, raw he shou wu, purple salvia root, raw rhubarb, and whole angelica root, as raw materials. After pulverizing, extracting, and filtering, a hair growth essence is obtained. However, the hair loss treatment effect of this product is not significant. Currently, other cosmetic compositions for treating hair loss on the market contain active ingredients that are very difficult to penetrate the skin, and cannot achieve substantial effects in preventing hair loss or improving scalp health. Summary of the Invention

[0004] Therefore, in order to solve the above problems, the present invention provides a method for improving scalp health through hair growth and care. This method is achieved by preparing a hair growth essence including a hair growth promoting composition and applying it to the surface of a scalp with health problems.

[0005] The preparation process of the hair growth essence comprising a hair growth promoting composition includes at least the following steps: (1) Preparation of a hair growth promoting composition; (2) The hair growth promoting composition prepared is mixed with the active ingredient composition to obtain a hair growth essence product.

[0006] As a preferred technical solution, the raw materials for preparing the hair growth promoting composition in step (1) by weight include at least the following components: 0.5-2 parts of active protein, 0.01-2 parts of complex amino acids, 0.01-1 parts of dihydroquercetin glucoside, 0.01-0.1 parts of epigallocatechin-3-gallate-glucoside, 0.1-1 parts of diguanidine tetraphosphate, and 4-8 parts of carboxymethyl chitosan.

[0007] As a preferred technical solution, the active protein includes at least one of hydrolyzed rice protein, hair growth peptide, potent active protein, and stem cell stimulating protein; preferably, the active protein is a combination of hydrolyzed rice protein, hair growth peptide, potent active protein, and stem cell stimulating protein; the mass ratio of the hydrolyzed rice protein, hair growth peptide, potent active protein, and stem cell stimulating protein is (6-10):(3-5):(1-3):(0.8-1.2); based on the system of the present invention, by introducing the above-mentioned active protein, especially the hydrolyzed rice protein, hair growth peptide, potent active protein, and stem cell stimulating protein included in the mass ratio of (6-10):(3-5):(1-3):(0.8-1.2), under the action of other active ingredients and raw materials in the system, it can effectively penetrate the scalp, quickly stimulate scalp stem cells, induce dermal and hair follicle cell differentiation, activate hair follicles, greatly accelerate the growth of new hair, help hair and skin resist free radicals, effectively prevent cell aging, and improve scalp health.

[0008] The compound amino acids were purchased from Shanghai Baihaobo Chemical Co., Ltd.

[0009] As a preferred technical solution, the mass ratio of dihydroquercetin glucoside to epigallocatechin-3-gallate-glucoside is (0.08-0.3):(0.04-0.08). Preferably, the dihydroquercetin glucoside (DHQG) is derived from one of Mongolian oak extract, fir extract, and larch extract; preferably, the epigallocatechin-3-gallate-glucoside (EGCG) is derived from one of camellia flower, walnut, apple peel, and tea. Based on the system of this invention, by controlling the mass ratio of introduced dihydroquercetin glucoside and epigallocatechin-3-gallate-glucoside to (0.08-0.3):(0.04-0.08), the two can synergistically inhibit the expression of inflammatory factors, promote the activation and lipid proliferation of hair follicle cells, and cause the dermal cells of hair follicles that were lost in the resting phase to re-expand, thus promoting rapid hair growth. On the other hand, it prevents hair loss by strengthening hair anchoring and activating hair follicle regeneration, maintains hair health by increasing nutrient and oxygen supply through vasodilation, inhibits the conversion of testosterone to dihydrotestosterone, and delays scalp cell aging.

[0010] As a preferred technical solution, the mass ratio of diguanidine tetraphosphate to carboxymethyl chitosan is (0.4-0.8):(4-6). Based on the system of the present invention, by controlling the hair growth promotion composition to have a mass ratio of diguanidine tetraphosphate to carboxymethyl chitosan of (0.4-0.8):(4-6), the growth of scalp bacteria and fungi is effectively inhibited, thereby inhibiting inflammation and improving scalp health, and the provided composition maintains better stability under high and low temperature conditions.

[0011] Preferably, the hair growth promoting composition in step (1) is prepared by stirring and mixing active protein, complex amino acids, dihydroquercetin glucoside, epigallocatechin-3-gallate-glucoside, diguanidine tetraphosphate, and carboxymethyl chitosan.

[0012] As a preferred technical solution, the mass ratio of the hair growth promoting composition to the effective ingredient composition in step (2) is (0.1-12):(88-99.9); preferably, the mass ratio of the hair growth promoting composition to the effective ingredient composition in step (2) is (6-10):(90-94). As a preferred technical solution, the active ingredient composition comprises, by weight, at least 8-12 parts of amino acid surfactant, 0.5-1 part of antioxidant, 4-8 parts of alcohol compound, and 75-80 parts of deionized water; As a preferred technical solution, the amino acid surfactant is sodium lauroyl glutamate. Based on the system of the present invention, the use of sodium lauroyl glutamate as an amino acid surfactant fully ensures the stability of the system.

[0013] As a preferred technical solution, the antioxidant is at least one selected from lutein, retinaldehyde, and carotene. Preferably, the antioxidant is carotene.

[0014] As a preferred technical solution, the alcohol compound is glycerol; As a preferred technical solution, the specific preparation method of the hair growth essence product in step (2) includes at least the following steps: S1. The active ingredient composition is obtained by stirring and mixing amino acid surfactants, antioxidants, alcohol compounds and deionized water at 40-50℃ for 10-20 minutes. S2. Control the temperature to 30-40℃, add the hair growth promoting composition to the active ingredient composition, stir and mix for 20-40 minutes to obtain the hair growth essence.

[0015] Based on the system of this invention, under a specific formula, by designing a preparation process for hair growth essence products, the effective ingredient composition is first prepared at 40-50℃, and then the hair growth promoting composition is added to the effective ingredient composition at a controlled temperature of 30-40℃ to prepare the hair growth promoting composition system, which has good physicochemical stability.

[0016] Another aspect of the present invention provides an application of a hair growth and care method for improving scalp health, applicable to improving scalp health, treating hair loss, and caring for and nourishing hair.

[0017] Beneficial effects: 1. This invention provides a method for improving scalp health through hair growth and care. The method involves preparing a hair growth essence comprising a hair growth promoting composition and applying it to the surface of a scalp with health problems. This method is used to improve scalp health, treat hair loss, and care for hair.

[0018] 2. Based on the system of the present invention, by introducing the above-mentioned active proteins, especially hydrolyzed rice protein, hair growth peptides, potent active proteins, and stem cell stimulating proteins in a mass ratio of (6-10):(3-5):(1-3):(0.8-1.2), under the action of other active ingredients and raw materials in the system, it can effectively penetrate the scalp, quickly stimulate scalp stem cells, induce dermal and hair follicle cell differentiation, activate hair follicles, greatly accelerate the growth of new hair, help hair and skin resist free radicals, effectively prevent cell aging, and improve scalp health. 3. Based on the system of this invention, by controlling the mass ratio of introduced dihydroquercetin glucoside and epigallocatechin-3-gallate-glucoside to (0.08-0.3):(0.04-0.08), the two can synergistically inhibit the expression of inflammatory factors, promote the activation and lipid proliferation of hair follicle cells, and cause the dermal cells of hair follicles lost in the resting phase to re-expand, thus promoting rapid hair growth. On the other hand, it prevents hair loss by strengthening hair anchoring and activating hair follicle regeneration, maintains hair health by increasing nutrient and oxygen supply through vasodilation, inhibits the conversion of testosterone to dihydrotestosterone, and delays scalp cell aging.

[0019] 4. Based on the system of the present invention, by controlling the mass ratio of diguanidine tetraphosphate and carboxymethyl chitosan in the hair growth promoting composition to (0.4-0.8):(4-6), the growth of scalp bacteria and fungi is effectively inhibited, thereby inhibiting inflammation and improving scalp health, and the provided composition maintains better stability under high and low temperature conditions.

[0020] 5. Based on the system of the present invention, under a specific formula, by designing a preparation process for hair growth essence products, the effective ingredient composition is first prepared at 40-50℃, and then the hair growth promoting composition is added to the effective ingredient composition at a controlled temperature of 30-40℃ to obtain the hair growth promoting composition system with good physicochemical stability. Detailed Implementation

[0021] Example 1 Embodiment 1 of the present invention provides a method for improving scalp health through hair growth and care. This method is achieved by preparing a hair growth essence comprising a hair growth promoting composition and applying it to the surface of a scalp with health problems.

[0022] The preparation process of the hair growth essence including the hair growth promoting composition includes the following steps: (1) Preparation of a hair growth promoting composition; (2) The hair growth promoting composition prepared is mixed with the active ingredient composition to obtain a hair growth essence product.

[0023] By weight, the raw materials for preparing the hair growth promoting composition in step (1) include the following components: 1.5 parts of active protein, 1 part of complex amino acids, 0.2 parts of dihydroquercetin glucoside, 0.06 parts of epigallocatechin-3-gallate-glucoside, 0.6 parts of diguanidine tetraphosphate, and 5 parts of carboxymethyl chitosan.

[0024] The active protein is a combination of hydrolyzed rice protein, hair growth peptide, active protein, and stem cell stimulating protein; the mass ratio of the hydrolyzed rice protein, hair growth peptide, active protein, and stem cell stimulating protein is 8:4:2:1.

[0025] The compound amino acids were purchased from Shanghai Baihaobo Chemical Co., Ltd.

[0026] The mass ratio of dihydroquercetin glucoside to epigallocatechin-3-gallate-glucoside is 0.2:0.06. The dihydroquercetin glucoside (DHQG) is derived from fir extract; the epigallocatechin-3-gallate-glucoside (EGCG) is derived from camellia flower. The mass ratio of diguanidine tetraphosphate to carboxymethyl chitosan is 0.6:5.

[0027] The hair growth promoting composition in step (1) is prepared by mixing active protein, complex amino acids, dihydroquercetin glucoside, epigallocatechin-3-gallate-glucoside, guanidine tetraphosphate, and carboxymethyl chitosan.

[0028] In step (2), the mass ratio of the hair growth promoting composition to the active ingredient composition is 8.36:91.64; The active ingredient composition, by weight, includes 10 parts of amino acid surfactant, 0.64 parts of antioxidant, 5 parts of alcohol compound, and 76 parts of deionized water; The amino acid surfactant is sodium lauroyl glutamate; The antioxidant is carotene.

[0029] The alcohol compound is glycerol.

[0030] The specific preparation method of the hair growth essence product in step (2) includes the following steps: S1. An active ingredient composition is obtained by stirring and mixing amino acid surfactants, antioxidants, alcohol compounds, and deionized water at 45°C for 15 minutes. S2. Control the temperature at 35℃, add the hair growth promoting composition to the active ingredient composition, stir and mix for 30 minutes to obtain the hair growth essence.

[0031] Another aspect of Embodiment 1 of the present invention provides an application of a hair growth and care method for improving scalp health, which is applied to improving scalp health, treating hair loss, and caring for and nourishing hair.

[0032] Example 2 Example 2 of the present invention provides a method for improving scalp health and hair growth and care, and its application. The specific preparation method is the same as that in Example 1, except that, by weight, the raw materials for preparing the hair growth promoting composition in step (1) include the following components: 1.5 parts of active protein, 1 part of complex amino acids, 0.18 parts of dihydroquercetin glucoside, 0.08 parts of epigallocatechin-3-gallate-glucoside, 0.6 parts of diguanidine tetraphosphate, and 5 parts of carboxymethyl chitosan.

[0033] Example 3 Example 3 of the present invention provides a method for improving scalp health through hair growth and care, and its application. The specific preparation method is the same as that in Example 1, except that the specific preparation method of the hair growth essence product in step (2) includes the following steps: S1. An active ingredient composition is obtained by stirring and mixing amino acid surfactants, antioxidants, alcohol compounds, and deionized water at 20°C for 15 minutes. S2. Control the temperature at 20℃, add the hair growth promoting composition to the active ingredient composition, stir and mix for 30 minutes to obtain the hair growth essence.

[0034] Performance testing methods (1) Physicochemical stability: The hair growth essence product prepared in the example was placed in a constant temperature chamber at 50℃, 25℃ and 0℃ for 14 days. After 14 days, it was taken out and observed. The state of the hair growth essence product at 50℃, 25℃ and 0℃ was observed. If the product did not separate into layers, the physicochemical stability was recorded as "qualified"; if the product separated into layers, the physicochemical stability was recorded as "unqualified". The results are shown in Table 1.

[0035] (2) Efficacy test: (1) Test the effects of the hair growth stem cell essence product provided in Example 1 on hair growth, scalp health and prevention of baldness in individuals with severe hair loss.

[0036] 1) A 34-year-old male patient used the product provided in Example 1, applying it twice daily to the balding areas of his scalp for four consecutive months. Photorecognition of the patient's scalp revealed a significant increase in new hair follicles and new hair tips. These follicles were stronger and thicker, increasing the coverage of the affected area of ​​the scalp by increasing hair volume.

[0037] 2) A 55-year-old woman used the product provided in Example 1 and applied it twice a day to the balding areas of her scalp. After two months of continuous use, the patient reported that her scalp and head had improved, her hair had grown and increased in volume, and her scalp felt healthy.

[0038] 3) A 61-year-old male used the product provided in Example 1 and applied it twice daily to the balding areas of his scalp. After two months of continuous use, the patient reported an increase in new hair follicles and new hair growth, which were stronger and thicker, resulting in increased scalp coverage.

[0039] (2) Test the dependence and effect of individuals with severe hair loss on the hair growth stem cell essence product provided in Example 1.

[0040] 1) Ten subjects with severe hair loss used the hair growth stem cell essence product provided in Example 1, applying it twice a day to the hair loss area of ​​the scalp for 8 consecutive weeks. After stopping use, hair growth still existed and continued, proving that the product has low dependence.

[0041] 2) Two female subjects with severe hair loss and thinning hair used the product provided in Example 1 for 6 weeks, applying it twice a day to the hair loss area of ​​the scalp. Photosensitive physical examination showed that the subjects had a significant increase in new hair follicles and a substantial increase in hair volume.

[0042] 3) In 8 male subjects with varying degrees of hair loss, the product provided in Example 1 was applied twice daily to the balding areas of the scalp for four consecutive weeks. Photosensitive physical examination showed that the subjects exhibited a significant peach-like effect in the growth of new terminal hairs, increasing scalp coverage and resulting in stronger and thicker hair.

Claims

1. A method for promoting hair growth and conditioning hair to improve scalp health, characterized in that, This method is achieved by preparing a hair growth essence comprising a hair growth promoting composition and applying it to the surface of a scalp with health problems.

2. The hair growth and care method for improving scalp health according to claim 1, characterized in that, The preparation process of the hair growth essence comprising a hair growth promoting composition includes at least the following steps: (1) Preparation of a hair growth promoting composition; (2) The hair growth promoting composition prepared is mixed with the active ingredient composition to obtain a hair growth essence product.

3. The hair growth and care method for improving scalp health according to claim 2, characterized in that, By weight, the raw materials for preparing the hair growth promoting composition in step (1) include at least the following components: 0.5-2 parts of active protein, 0.01-2 parts of complex amino acids, 0.01-1 parts of dihydroquercetin glucoside, 0.01-0.1 parts of epigallocatechin-3-gallate-glucoside, 0.1-1 parts of diguanidine tetraphosphate, and 4-8 parts of carboxymethyl chitosan.

4. The hair growth and care method for improving scalp health according to claim 3, characterized in that, The active protein includes at least one of hydrolyzed rice protein, hair growth peptide, potent active protein, and stem cell stimulating protein.

5. A method for improving scalp health and promoting hair growth according to claim 4, characterized in that, The mass ratio of dihydroquercetin glucoside to epigallocatechin-3-gallate-glucoside is (0.08-0.3):(0.04-0.08).

6. A method for improving scalp health and promoting hair growth according to claim 5, characterized in that, The dihydroquercetin glucoside is derived from one of the following: Mongolian oak extract, fir extract, and larch extract.

7. A method for improving scalp health and promoting hair growth according to any one of claims 3-6, characterized in that, The hair growth promoting composition in step (1) is prepared by mixing active protein, complex amino acids, dihydroquercetin glucoside, epigallocatechin-3-gallate-glucoside, guanidine tetraphosphate, and carboxymethyl chitosan.

8. A method for improving scalp health and promoting hair growth according to claim 7, characterized in that, In step (2), the mass ratio of the hair growth promoting composition to the effective ingredient composition is (0.1-12):(88-99.9); the effective ingredient composition, by weight, includes at least 8-12 parts of amino acid surfactant, 0.5-1 parts of antioxidant, 4-8 parts of alcohol compound, and 75-80 parts of deionized water.

9. A method for improving scalp health and promoting hair growth according to claim 8, characterized in that, The specific preparation method of the hair growth essence product in step (2) includes at least the following steps: S1. The active ingredient composition is obtained by stirring and mixing amino acid surfactants, antioxidants, alcohol compounds and deionized water at 40-50℃ for 10-20 minutes. S2. Control the temperature to 30-40℃, add the hair growth promoting composition to the active ingredient composition, stir and mix for 20-40 minutes to obtain the hair growth essence.

10. An application of the hair growth and care method for improving scalp health according to claim 9, characterized in that, It is used to improve scalp health, treat hair loss, and care for hair.

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