Anti-aging lifting skin care essence as well as preparation method and application thereof
By combining sodium hyaluronate with other ingredients, the problem of deep penetration in existing serums has been solved, achieving multiple skincare effects such as deep penetration, long-lasting hydration, and anti-wrinkle firming, while enhancing the skin's deep nourishment and structural repair capabilities.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
- Filing Date
- 2026-02-14
- Publication Date
- 2026-05-12
AI Technical Summary
Existing serums are unable to achieve deep penetration, resulting in active ingredients not being able to effectively reach the dermis, thus failing to simultaneously achieve multiple skincare goals such as deep penetration, long-lasting hydration, and anti-wrinkle and firming effects.
It uses a combination of ingredients such as sodium hyaluronate, moisturizers, antioxidants, pH adjusters, chelating agents and skin conditioning agents. The sodium hyaluronate of different molecular weights achieves high permeability and long-lasting moisturizing. Combined with the multiple targeted effects of skin conditioning agents, it forms a firming, lifting and anti-wrinkle effect.
It achieves multiple skincare goals, including deep penetration, long-lasting hydration, and anti-wrinkle firming, enhancing the skin's deep nourishment and structural repair effects.
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Figure CN122005357A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of skincare technology, specifically to an anti-aging and lifting skincare essence, its preparation method, and its application. Background Technology
[0002] With social progress, economic development, and the continuous improvement of people's living standards, people's demand for beauty, skincare, and cosmetics is also upgrading. While pursuing beauty, consumers are paying more and more attention to the efficacy of products, driving the beauty industry towards a more targeted direction.
[0003] As a core category in skincare, serums play a crucial role in skin management with their high concentration of active ingredients and precise formulations. They can penetrate deep into the skin to achieve effects such as anti-aging, wrinkle reduction, skin brightening, skin texture evening, and pigmentation inhibition. However, most serums on the market currently use sodium hyaluronate as their main ingredient, which makes it difficult to achieve effective deep skin penetration. As a result, most active ingredients remain only in the epidermis and cannot reach the dermis for long-term nourishment and structural repair. Therefore, they often fail to simultaneously achieve multiple skincare goals such as deep penetration, long-lasting hydration, and anti-wrinkle firming, and their actual efficacy is significantly limited. Summary of the Invention
[0004] This invention provides an anti-aging and lifting skincare essence, its preparation method, and its application, which can achieve multiple skincare goals such as deep penetration, long-lasting moisturizing, and anti-wrinkle and firming.
[0005] According to a first aspect of the present invention, an anti-aging and lifting skin care essence is provided, comprising, by weight, the following components: 0.01-6 parts sodium hyaluronate, 1-30 parts moisturizer, 0.1-1 part antioxidant, 0.01-1 part pH adjuster, 0.01-0.1 part chelating agent, 1-10 parts skin conditioning agent, and 50-85 parts water.
[0006] Optionally, sodium hyaluronate includes at least one of sodium hyaluronate with a molecular weight of 800-1500 kDa, sodium hyaluronate with a molecular weight of 10-1000 kDa, sodium hyaluronate with a molecular weight of 2-8 kDa, acetylated sodium hyaluronate, and cross-linked sodium hyaluronate.
[0007] And / or, the moisturizer includes at least one of glycerin, 1,3-propylene glycol, 1,2-propylene glycol, dipropylene glycol, butylene glycol, 1,2-pentanediol, methyl gluceth-20, 1,2-hexanediol and 2,3-butanediol;
[0008] And / or, antioxidants include at least one of p-hydroxyacetophenone, tocopherol, and ergothioneine;
[0009] And / or, the pH adjuster includes at least one of sodium hydroxide, potassium hydroxide, arginine, triethanolamine, citric acid, and sodium citrate;
[0010] And / or, the chelating agent includes at least one of sodium phytate, gluconolactone, and disodium EDTA.
[0011] Optionally, by weight, sodium hyaluronate comprises: 0.01-1 part of sodium hyaluronate with a molecular weight of 800-1500 kDa, 0.01-2 parts of sodium hyaluronate with a molecular weight of 10-1000 kDa, and 0.01-3 parts of sodium hyaluronate with a molecular weight of 2-8 kDa.
[0012] And / or, by weight, the moisturizer includes: 1-5 parts butylene glycol and 0.1-5 parts 1,2-hexanediol;
[0013] And / or, the antioxidant is p-hydroxyacetophenone;
[0014] And / or, by weight, the pH adjuster includes: 0.001-0.1 parts arginine and 0.001-0.1 parts citric acid;
[0015] And / or, the chelating agent is disodium ethylenediaminetetraacetate.
[0016] Optionally, skin conditioning agents include niacinamide, Ganoderma lucidum extract, and complex peptides;
[0017] The complex polypeptides include dipeptide diaminobutyryl benzylamide diacetate, acetyl hexapeptide-8, palmitoyl pentapeptide-5, and arginine / lysine polypeptide.
[0018] Optionally, the skin conditioning agents also include daisy flower extract, sodium mannose phosphate, and soursop fruit extract.
[0019] Optionally, the skin conditioning agent may include, by weight, 1-5 parts niacinamide, 0.01-1 part daisy extract, 0.01-1 part Ganoderma lucidum extract, 0.01-1 part complex polypeptide, 0.01-1 part sodium mannose phosphate, and 0.01-1 part custard apple fruit extract.
[0020] Optionally, skin conditioning agents include caffeine and ascorbic acid peptides.
[0021] Optionally, skin conditioning agents may also include niacinamide and quinoa seed extract;
[0022] And / or, the ascorbic acid peptide is a stable vitamin C derivative.
[0023] Optionally, the skin conditioning agent may include, by weight, 1-5 parts niacinamide, 0.01-1 part ascorbic acid peptide, and 0.01-1 part quinoa seed extract.
[0024] Optionally, skin conditioning agents include bakuchiol, thermophilic bacteria ferment products, and collagen.
[0025] Optionally, the skin conditioning agent may also include magnolia flower extract.
[0026] Optionally, the skin conditioning agent may include, by weight, 0.01-1 part of thermophilic bacteria fermentation product, 0.01-1 part of magnolia flower extract, and 0.00001-0.1 part of collagen.
[0027] According to a second aspect of the present invention, a method for preparing an anti-aging and lifting skincare essence is provided, comprising:
[0028] Add water to the emulsification pot, then add sodium hyaluronate, moisturizer, antioxidant, pH adjuster and chelating agent to the emulsification pot, heat to 80-85℃ and stir to obtain the first mixture;
[0029] Cool the first mixture to 40-45℃, then add the skin conditioning agent and mix to obtain the second mixture;
[0030] Cool the second mixture to 30-35℃ to obtain an anti-aging and lifting skincare essence.
[0031] According to a third aspect of the present invention, the application of the above-mentioned anti-aging and lifting skincare essence in skincare products is provided.
[0032] The anti-aging and lifting skincare essence provided by this invention comprises, by weight, the following components: 0.01-6 parts sodium hyaluronate, 1-30 parts moisturizer, 0.1-1 part antioxidant, 0.01-1 part pH adjuster, 0.01-0.1 part chelating agent, 1-10 parts skin conditioning agent, and 50-85 parts water. Through the synergistic effect of sodium hyaluronate with moisturizer, antioxidant, pH adjuster, chelating agent, skin conditioning agent, and water, high permeability and long-lasting hydration are achieved. Furthermore, the addition of skin conditioning agent provides multiple targeted effects (such as anti-wrinkle and brightening, firming and lifting, and wrinkle reduction), thus enabling the anti-aging and lifting skincare essence to achieve multiple skincare goals: deep penetration, long-lasting hydration, and anti-wrinkle and firming effects. Attached Figure Description
[0033] To more clearly illustrate the technical solutions in the embodiments of the present invention, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0034] Figure 1This is a comparison of the effects of the essence in Example 2. Figure 1 ;
[0035] Figure 2 This is a comparison of the effects of the essence in Example 2. Figure 2 ;
[0036] Figure 3 This is a comparison of the effects of the essence in Example 3. Figure 1 ;
[0037] Figure 4 This is a comparison of the effects of the essence in Example 3. Figure 2 . Detailed Implementation
[0038] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.
[0039] The following embodiments provide an anti-aging and lifting skincare essence, its preparation method, and its application. Detailed descriptions are provided below. It should be noted that the order of description in the following embodiments is not intended to limit the preferred order of the embodiments. Furthermore, in the description of this invention, the term "comprising" means "including but not limited to". The terms first, second, third, etc., are used merely as illustrative and do not impose numerical requirements or establish an order. Various embodiments of this invention may exist in the form of a range; it should be understood that the description in the form of a range is merely for convenience and brevity and should not be construed as a rigid limitation on the scope of the invention; therefore, it should be considered that the range description has specifically disclosed all possible sub-ranges and single numerical values within that range. For example, it should be considered that the range description from 1 to 6 has specifically disclosed sub-ranges, such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6, etc., and single numbers within the range, such as 1, 2, 3, 4, 5, and 6, regardless of the range. Additionally, whenever a numerical range is indicated herein, it means including any referenced number (fraction or integer) within the indicated range.
[0040] In a first aspect, embodiments of the present invention provide an anti-aging and lifting skin care essence, comprising the following components by weight: 0.01-6 parts sodium hyaluronate, 1-30 parts moisturizer, 0.1-1 part antioxidant, 0.01-1 part pH adjuster, 0.01-0.1 part chelating agent, 1-10 parts skin conditioning agent, and 50-85 parts water.
[0041] The anti-aging and lifting skincare essence provided in this invention comprises, by weight, the following components: 0.01-6 parts sodium hyaluronate, 1-30 parts moisturizer, 0.1-1 part antioxidant, 0.01-1 part pH adjuster, 0.01-0.1 part chelating agent, 1-10 parts skin conditioning agent, and 50-85 parts water. Through the synergistic effect of sodium hyaluronate with moisturizer, antioxidant, pH adjuster, chelating agent, skin conditioning agent, and water, high permeability and long-lasting hydration are achieved. Furthermore, the addition of skin conditioning agent provides multiple targeted effects (e.g., anti-wrinkle and brightening, firming and lifting, and wrinkle reduction), thus enabling the anti-aging and lifting skincare essence to achieve multiple skincare goals: deep penetration, long-lasting hydration, and anti-wrinkle and firming effects.
[0042] In some embodiments, sodium hyaluronate includes at least one of sodium hyaluronate with a molecular weight of 800-1500 kDa, sodium hyaluronate with a molecular weight of 10-1000 kDa, sodium hyaluronate with a molecular weight of 2-8 kDa, acetylated sodium hyaluronate, and cross-linked sodium hyaluronate.
[0043] Sodium hyaluronate with a molecular weight of 800-1500 kDa can form a breathable hydrating film on the skin surface, reducing transepidermal water loss, improving water retention, and its higher viscosity can soothe the skin. Sodium hyaluronate with a molecular weight of 10-1000 kDa can penetrate into the intercellular space of the stratum corneum, replenishing intercellular lipids, enhancing the skin's hydration capacity, and its lower viscosity reduces stickiness. Sodium hyaluronate with a molecular weight of 2-8 kDa can reach the dermis, promoting fibroblast activity, stimulating collagen synthesis, and has anti-wrinkle and repairing effects. Acetylated sodium hyaluronate is lipid-soluble, enhancing its adhesion to the stratum corneum and helping to form a tight moisturizing film. Cross-linked sodium hyaluronate has a three-dimensional network structure, which can form a stable gel through chemical cross-linking, prolonging the water release time and exhibiting anti-degradation properties.
[0044] In some embodiments, the humectant includes at least one of the following polyols: glycerin, 1,3-propylene glycol, 1,2-propylene glycol, dipropylene glycol, butylene glycol, 1,2-pentanediol, methyl gluceth-20, 1,2-hexanediol, and 2,3-butanediol.
[0045] The above substances are all rich in hydrogen groups, which can form hydrogen bonds with water molecules and improve their moisturizing properties.
[0046] In some embodiments, the antioxidant includes at least one of p-hydroxyacetophenone, tocopherol, and ergothioneine.
[0047] p-Hydroxyacetophenone can reduce lipid oxidation and free radical generation by chelating metal ions, and it is highly stable and resistant to acids and alkalis. Tocopherol can neutralize peroxidation free radicals in lipids and terminate chain reactions. Ergothioneine can scavenge superoxide ions and can penetrate cell membranes.
[0048] In some embodiments, the pH adjuster includes at least one of sodium hydroxide, potassium hydroxide, arginine, triethanolamine, citric acid, and sodium citrate.
[0049] All of the above substances are either acidic or alkaline, can be used to adjust pH, and have good stability and safety.
[0050] In some embodiments, the chelating agent includes at least one of sodium phytate, gluconolactone, and disodium EDTA.
[0051] Sodium hyaluronate has multiple phosphate groups, enabling it to form stable chelates with metal ions and reduce their oxidation. Gluconolactone can capture ions such as iron and copper, preventing oxidation and discoloration. As a polyhydroxy acid, its large molecular weight and slow penetration reduce irritation. Disodium ethylenediaminetetraacetate contains four carboxyl groups and two nitrogen atoms, allowing it to form stable chelates with most divalent metal ions, inhibiting free radical generation and ensuring antioxidant effects.
[0052] In some embodiments, sodium hyaluronate comprises, by weight: 0.01-1 part of sodium hyaluronate with a molecular weight of 800-1500 kDa, 0.01-2 parts of sodium hyaluronate with a molecular weight of 10-1000 kDa, and 0.01-3 parts of sodium hyaluronate with a molecular weight of 2-8 kDa.
[0053] By using sodium hyaluronate with different molecular weights, layered moisturizing can be achieved, allowing sodium hyaluronates of different molecular weights to exert a good synergistic effect, breaking the efficacy limitations of sodium hyaluronate with a single molecular weight.
[0054] In some embodiments, the humectant includes, by weight, 1-5 parts of butylene glycol and 0.1-5 parts of 1,2-hexanediol.
[0055] By combining butylene glycol and 1,2-hexanediol, the rapid hydration of butylene glycol and the long-lasting moisture retention of 1,2-hexanediol can be utilized to improve the overall moisturizing effect. Both are low in irritation, highly stable, and have a good skin feel.
[0056] In some embodiments, the antioxidant is p-hydroxyacetophenone.
[0057] In some embodiments, the pH adjuster comprises, by weight, 0.001-0.1 parts arginine and 0.001-0.1 parts citric acid.
[0058] By using arginine and citric acid as pH adjusters, a buffer system can be formed with anti-interference capabilities, enabling dynamic pH regulation.
[0059] In some embodiments, the chelating agent is disodium ethylenediaminetetraacetate.
[0060] In some embodiments, the skin conditioning agent includes niacinamide, Ganoderma lucidum extract, and a complex peptide. The complex peptide includes dipeptide diaminobutyryl benzylamide diacetate, acetyl hexapeptide-8, palmitoyl pentapeptide-5, and arginine / lysine peptide.
[0061] Niacinamide (chemical formula C6H6N2O) is an amide compound of nicotinic acid and an essential water-soluble vitamin for the human body. It can inhibit the transport of melanin to keratinocytes, accelerate keratin metabolism, lighten pigmentation, and improve dullness. It can also promote the synthesis of ceramides and free fatty acids, strengthen the skin's moisture barrier, reduce moisture loss, and relieve sensitivity and redness. Furthermore, it can regulate sebum secretion, reduce oil production and enlarged pores, help inhibit Propionibacterium acnes, stimulate collagen production, reduce glycation, and improve fine lines and skin elasticity. In the complex polypeptide, the dipeptide diaminobutyryl benzylamide diacetate (a snake venom-like peptide) can antagonize acetylcholine receptors and reduce muscle cell contraction; acetyl hexapeptide-8 can specifically inhibit the formation of the SNARE complex and reduce acetylcholine levels; and palmitoyl pentapeptide-5 can target and close Ca2+ receptors. 2+ Channels; arginine / lysine peptides can act on multiple ion channels and can block Na+. + Channels. The complex peptides can comprehensively block signal transmission through the combined action of the pre-, mid-, and post-channels, thereby achieving the goal of rapidly reducing wrinkles.
[0062] In some embodiments, the skin conditioning agent also includes daisy flower extract, sodium mannose phosphate, and soursop fruit extract.
[0063] Daisy flower extract is rich in flavonoids and polyphenols, possessing a powerful ability to scavenge free radicals, significantly reducing the expression of inflammatory factors, and relieving skin redness and sensitivity. Sodium mannose phosphate contains hydrophilic groups, which can absorb moisture, enhance moisturizing effects, and promote keratinocyte differentiation, repairing damaged skin barriers. Anelmint leaf extract contains polyphenols and alkaloids, which can inhibit matrix metalloproteinase activity, reduce collagen activity, enhance fibroblast activity, and stimulate collagen synthesis.
[0064] This skin conditioning agent contains niacinamide, Ganoderma lucidum extract, complex peptides, daisy flower extract, sodium mannose phosphate, and Annona squamosa fruit extract. Combined with other ingredients in the anti-aging and lifting skincare essence, it offers multiple functions including highly effective hydration, long-lasting moisturizing, anti-aging, wrinkle reduction, firming, and skin barrier repair. Furthermore, the anti-aging and lifting skincare essence effectively repairs damaged keratinocytes, deeply nourishes the skin, improves skin texture, and enhances cell activity, thereby achieving a comprehensive anti-aging effect that smooths wrinkles, strengthens the skin's foundation, and provides lasting rejuvenation.
[0065] In some embodiments, the skin conditioning agent comprises, by weight, 1-5 parts niacinamide, 0.01-1 part daisy extract, 0.01-1 part Ganoderma lucidum extract, 0.01-1 part complex polypeptide, 0.01-1 part sodium mannose phosphate, and 0.01-1 part custard apple fruit extract.
[0066] By including the above-mentioned components in the skin conditioning agent, the effects of each component can be balanced, achieving a good synergistic effect.
[0067] In some embodiments, the skin conditioning agent includes caffeine and ascorbic acid peptides.
[0068] Caffeine, as a natural alkaloid and a powerful antioxidant, can combat oxidative damage from photopollutation by scavenging free radicals, synergistically strengthening the anti-photoaging protection system. Furthermore, as a phosphodiesterase inhibitor, it effectively promotes subcutaneous microcirculation, accelerates the metabolism of water and metabolic waste, reduces puffiness, and helps regulate local fat metabolism, contributing to a firmer contour and reduced under-eye cellulite. In addition, caffeine possesses clear anti-inflammatory and soothing properties, helping to alleviate skin redness and stress responses, and enhancing skin tolerance. The circulation-promoting, anti-swelling, antioxidant, and anti-inflammatory effects of caffeine, combined with the three-dimensional moisturizing network of sodium hyaluronate, can achieve comprehensive anti-aging goals such as firmer, more defined contours, and a radiant complexion.
[0069] In some embodiments, the skin conditioning agent also includes niacinamide and quinoa seed extract.
[0070] The effects of niacinamide have been described above and will not be repeated here. Quinoa seed extract is a small-molecule plant polypeptide active ingredient. Its natural plant carnitine can promote the breakdown of fat cells, helping to reduce fat accumulation under the eyes; at the same time, it can stimulate the synthesis of extracellular matrix proteins and enhance the integrity of skin structure, thereby achieving multiple skin care goals such as improving eye bags and smoothing fine lines.
[0071] In some embodiments, the ascorbic acid peptide is a stable vitamin C derivative.
[0072] Stable vitamin C derivatives significantly improve the stability of the components while maintaining high biocompatibility, effectively overcoming the technical bottleneck of traditional vitamin C's susceptibility to oxidative inactivation. Stable vitamin C derivatives exhibit significant anti-aging effects in improving skin elasticity, evening skin tone, and reducing wrinkles.
[0073] By using skin conditioning agents including caffeine, ascorbic acid peptides, niacinamide, and quinoa seed extract, combined with other components such as sodium hyaluronate in the anti-aging and lifting skin care essence, it can achieve a complex anti-aging effect that combines anti-oxidation, circulation promotion, edema reduction, wrinkle reduction and firming, and barrier repair.
[0074] In some embodiments, the skin conditioning agent comprises, by weight, 1-5 parts niacinamide, 0.01-1 parts ascorbic acid peptide, and 0.01-1 parts quinoa seed extract.
[0075] By including the above-mentioned components in the skin conditioning agent, the effects of each component can be balanced, achieving a good synergistic effect.
[0076] In some embodiments, the skin conditioning agent includes bakuchiol, thermophilic bacteria fermentation products, and collagen.
[0077] Bakuchiol is a pure terpene phenol abundant in the seeds and leaves of Psoralea corylifolia L. Its structure is similar to retinol, and its skincare effects are also similar. In in vitro experiments, bakuchiol can promote the production of type I, III, and IV collagen. Furthermore, human trials have shown that bakuchiol can improve wrinkles, lighten skin tone, increase skin elasticity and firmness, and reduce photodamage. It is gentler than retinol and is recommended as a retinol alternative. Fermentation products of *Thermus thermophilus* can scavenge free radicals and provide protection against mitochondrial damage caused by infrared radiation. It maintains mitochondrial hydration and structural integrity under environmental stress, optimizes cellular energy metabolism, and thus enhances skin hydration and vitality from the skin's base. Collagen can stimulate the synthesis of endogenous collagen in the skin, strengthen the dermal support structure, thereby improving skin elasticity, firmness, and facial contour definition.
[0078] In some embodiments, the skin conditioning agent also includes magnolia flower extract.
[0079] Magnolia biondii flower extract is rich in natural lignans such as magnolin and honokiol, which have excellent antioxidant and soothing repair effects. It helps to strengthen the skin barrier function, resist external stimuli, improve uneven skin tone, and smooth out early signs of aging.
[0080] By using skin conditioning agents including bakuchiol, thermophilic bacteria ferment products, collagen, and magnolia flower extract, combined with other components in the anti-aging and lifting skincare essence, it can synergistically achieve deep repair, antioxidant defense, collagen regeneration promotion, and long-lasting moisturizing, comprehensively improving the skin's internal health and external radiance.
[0081] In some embodiments, the skin conditioning agent comprises, by weight, 0.01-1 part of thermophilic bacteria fermentation product, 0.01-1 part of magnolia flower extract, and 0.00001-0.1 part of collagen.
[0082] By including the above-mentioned components in the skin conditioning agent, the effects of each component can be balanced, achieving a good synergistic effect.
[0083] The anti-aging and lifting skincare essence provided in this invention first establishes a common basic ingredient including sodium hyaluronate. Through differentiated formulations of skin conditioning agents, it can achieve the effects of anti-wrinkle and brightening, anti-swelling and anti-oxidation, and firming and reducing wrinkles, thus forming a complete skincare solution covering brightening, anti-aging and wrinkle reduction, and realizing a systematic and matrix-like product efficacy layout.
[0084] Secondly, embodiments of the present invention provide a method for preparing an anti-aging and lifting skincare essence, used to prepare the above-mentioned anti-aging and lifting skincare essence, comprising:
[0085] Add water to the emulsification pot, then add sodium hyaluronate, humectant, pH adjuster and chelating agent to the emulsification pot, heat to 80-85℃ and stir to obtain the first mixture;
[0086] Cool the first mixture to 40-45℃, then add the skin conditioning agent and mix to obtain the second mixture;
[0087] Cool the second mixture to 30-35℃ to obtain an anti-aging and lifting skincare essence.
[0088] The method for preparing the anti-aging and lifting skincare essence provided in this invention has all the beneficial effects of the anti-aging and lifting skincare essence described above, which will not be repeated here. Furthermore, the method for preparing the anti-aging and lifting skincare essence provided in this invention is simple, efficient, and suitable for large-scale production applications.
[0089] Thirdly, embodiments of the present invention provide the application of the above-mentioned anti-aging and lifting skincare essence in skincare products.
[0090] By applying the anti-aging and lifting skincare essence as described above to skincare products, high penetration and long-lasting hydration can be achieved. With the addition of skin care agents, multiple targeted effects can be achieved (such as anti-wrinkle and brightening, firming and lifting, and anti-wrinkle and wrinkle reduction). Thus, the anti-aging and lifting skincare essence can achieve multiple skincare goals of deep penetration, long-lasting hydration, and anti-wrinkle and firming.
[0091] For example, anti-aging and lifting skincare serums can be used in conjunction with beauty devices. By applying the serum to the skin's surface and then using the beauty device to promote absorption, the skincare effect can be enhanced.
[0092] Example 1
[0093] Prepare the basic serums according to the formulas in Table 1 (Formula 1, Formula 2, and Formula 3). In Table 1, "qs" indicates an appropriate amount to be added, and "To 100%" indicates to be supplemented to 100%, with the proportions being by weight.
[0094] Table 1
[0095]
[0096] Formulas 1, 2, and 3 provided in this embodiment utilize the synergistic effect of high molecular weight sodium hyaluronate, medium molecular weight sodium hyaluronate, and low molecular weight sodium hyaluronate. High molecular weight sodium hyaluronate ensures basic moisturizing effects, while low molecular weight sodium hyaluronate can penetrate the epidermis and reach the dermis, clearing free radicals in cells, reducing the activity of inflammatory factors, inhibiting inflammatory responses, thereby repairing damaged cells and reducing skin inflammation and sensitivity.
[0097] Sensory evaluation showed that the sample in Formula 2 exhibited moderate viscosity and a refreshing feel, combining excellent spreadability with a dry, clean finish after absorption. Human testing demonstrated good soothing and moisturizing effects.
[0098] Example 2
[0099] The formula of the anti-aging and lifting skincare essence in this embodiment is shown in Table 2. In Table 2, "qs" indicates an appropriate amount to be added, and "To 100%" indicates to be supplemented to 100%, with the proportions being by weight.
[0100] Table 2
[0101]
[0102] After human efficacy testing, it can achieve multiple effects such as soothing and brightening, improving firmness, and reducing wrinkles after use.
[0103] The test method is as follows: (1) Clean the skin and test the baseline data after 5 minutes; (2) Apply the serum to the right face with your hand and then use a beauty device (JM20, the same below) to import for 3 minutes, use a beauty device to import for 1 minute on the right forehead, and do not use serum or beauty device on the left face; (3) Take a photo with Meitu Yifu after use to monitor the immediate and long-term test results.
[0104] The test indicators included: skin texture, firmness, nasolabial fold area, soothing (a and E values), melanin, and ITA. Test time points were D1 (baseline data from day one), immediately (3 minutes after applying the serum), and D5 (daily use, morning application on day five, afternoon testing). Ten participants were tested, and the average value was taken.
[0105] The test results are shown in Table 3:
[0106] Table 3
[0107]
[0108] In Table 3, “△immediately” represents the difference between the test results 3 minutes after use and the baseline data, and “△5” represents the difference between the test results 5 days after use and the baseline data. Both are expressed as percentages. When the value is positive, it indicates an improvement relative to the baseline data, and when the value is negative, it indicates a decrease relative to the baseline data.
[0109] As shown in Table 3, the a-value, skin hemoglobin, and melanin levels decreased in the experimental group compared to the control group, while the ITA value increased, indicating improved skin redness and a lighter skin tone. The proportion of periorbital wrinkles, cheek skin texture score, and nasolabial fold area decreased in the experimental group compared to the control group, indicating a better anti-wrinkle effect in the experimental group. The elasticity R2 level increased in the experimental group compared to the control group, indicating a better immediate firming effect in the experimental group.
[0110] like Figure 1 and Figure 2 As shown, where Figure 1 and Figure 2 In the diagram, "D1" represents a photo taken one day after use, and "D7" represents a photo taken seven days after use. It can be seen that after one week of continuous use of the anti-aging and lifting skincare essence in Example 2, the subjects showed significant, visible improvements in skin brightness and smoothness.
[0111] This product, formulated with skin conditioning agents containing niacinamide, Ganoderma lucidum extract, complex peptides, daisy flower extract, sodium mannose phosphate, and Annona squamosa fruit extract, combined with other ingredients in its anti-aging and lifting skincare essence, offers multiple benefits including highly effective hydration, long-lasting moisturizing, anti-aging, wrinkle reduction, firming, and skin barrier repair. Furthermore, the anti-aging and lifting skincare essence effectively repairs damaged keratinocytes, deeply nourishes the skin, improves skin texture, and enhances cell activity, thereby achieving a comprehensive anti-aging effect that smooths wrinkles, strengthens the skin's foundation, and provides lasting rejuvenation.
[0112] Example 3
[0113] The formula of the anti-aging and lifting skincare essence in this embodiment is shown in Table 4. In Table 4, "qs" indicates an appropriate amount to be added, and "To 100%" indicates to be supplemented to 100%, with the proportions being by weight.
[0114] Table 4
[0115]
[0116] After human efficacy testing, it can achieve firming and swelling reduction effects after use.
[0117] The testing methods are as follows: (1) Cleanse face and test baseline data after 5 minutes; (2) D1, D2: 5 minutes after cleansing face, test all baseline values; then apply the basic essence of formula 2 in Example 1 to the left face and the essence of Example 3 to the right face; after 30 minutes, use Meitu Yifu to take a picture to test the chin angle values of the left and right faces of the V face; (3) D3: 5 minutes after cleansing face, test the baseline values of the left and right faces; then apply the basic essence of formula 2 in Example 1 to the left face and the essence of Example 3 to the right face; after applying the essence to the left and right faces for 3 minutes with a beauty device, gently pat the face to apply the essence. (4) D4: The left face used the basic essence of Formula 2 in Example 1, and the right face used the essence of Example 3; (5) D5: After cleansing the face, wait 5 minutes and test the data values of the left and right faces; then the left face used the basic essence of Formula 2 in Example 1, and the right face used the essence of Example 3; after applying the essence to the left and right faces for 3 minutes with the beauty device, gently pat the face until the essence is absorbed; (6) D6, D7: The left face used the basic essence of Formula 2 in Example 1, and the right face used the essence of Example 3; (7) D8: The subjects were followed up and the data values were tested after cleansing the face.
[0118] The test indicators include: skin firmness, hemoglobin content (EI value), red zone a value, skin color ITA value, subject sensory evaluation, moisture content, and V-shaped chin angle.
[0119] The test results are shown in Table 5:
[0120] Table 5
[0121]
[0122] In Table 5, “△1” represents the difference between the test results on the first day after use and the initial data, and “△7” represents the difference between the test results after 7 days of use and the baseline data. Both are expressed as percentages. When the value is positive, it indicates an improvement relative to the original data, and when the value is negative, it indicates a decrease relative to the original data.
[0123] As shown in Table 5, compared to the base group (left cheek treated with the base serum from Formula 2 of Example 1), the experimental group (right cheek treated with the serum from Example 3) showed a significant improvement in elasticity R2 and elasticity R5, indicating a marked increase in skin elasticity. The experimental group also showed a significant increase in ITA value, indicating a better effect on skin tone improvement. Compared to the base group, the experimental group showed a significant decrease in redness a value and heme content, indicating a better effect on improving heme content. Furthermore, compared to the base group, the experimental group also showed a significant increase in skin moisture content.
[0124] like Figure 3 and Figure 4 As shown, the subject's left cheek measured 33.543° immediately after using the anti-aging and lifting skincare essence in Example 3 (D1 immediate), which was significantly better than the baseline value of 43.345° before use (D1); after continued use until the second day (D2), the measured value further improved.
[0125] The temperature remained at 41.399°, still lower than the initial level. The results indicate that the anti-aging and lifting skincare essence in Example 3 has a significant immediate firming and anti-swelling effect, and can maintain a certain firming trend in the short term.
[0126] The product is formulated with skin conditioning agents including caffeine, ascorbic acid peptides, niacinamide, and quinoa seed extract, combined with other components such as sodium hyaluronate in the anti-aging and lifting skincare essence. This combination provides a complex anti-aging effect, including antioxidant properties, improved circulation, reduced puffiness, anti-wrinkle firming, and barrier repair.
[0127] Example 4
[0128] The formula of the anti-aging and lifting skincare essence in this embodiment is shown in Table 4. In Table 4, "qs" indicates an appropriate amount to be added, and "To 100%" indicates to be supplemented to 100%, with the proportions being by weight.
[0129] Table 6
[0130]
[0131] The anti-aging and lifting skincare essence in Example 4 was used for testing. The number of test participants was 10. The testing method was as follows: (1) Cleanse the face and test the baseline data after 5 minutes; (2) Day 1: After cleansing the face, test the baseline value after 5 minutes and distribute test samples (the left face was to use the basic essence of Formula 2 in Example 1, and the right face was to use the essence in Example 4); (3) Day 2: Cleanse the face and test the data after 5 minutes; (4) Day 3: After cleansing the face, wait 5 minutes and test the baseline values of the left and right faces; then the left face was to use the basic essence of Formula 2 in Example 1, and the right face was to use the essence in Example 4. After 3 minutes of beauty device application, gently apply the essence to the left face and the right face. (5) D4: Use the basic essence of Formula 2 in Example 1 on the left face and the essence of Example 4 on the right face; (6) D5: After cleansing the face, wait 5 minutes and test the baseline values of the left and right faces; then use the basic essence of Formula 2 in Example 1 on the left face and the essence of Example 4 on the right face. After 3 minutes of using a beauty device to import the essence, gently pat the face until the essence is absorbed and test the immediate indicators; (7) D6, D7: Use the basic essence of Formula 2 in Example 1 on the left face and the essence of Example 4 on the right face; (8) D8: Follow up with the subjects and test the data values after cleansing the face.
[0132] The test indicators include Meitu Skin Test (nasolabial folds, crow's feet), elasticity test, skin texture score, collagen content, moisture content, and subject sensory evaluation.
[0133] The test results are shown in Table 7:
[0134] Table 7
[0135]
[0136] In Table 7, "△1" represents the difference between the test results on the first day after use and the initial data, and "△7" represents the difference between the test results after 7 days of use and the baseline data. Both are expressed as percentages. When the value is positive, it indicates an improvement relative to the original data, and when the value is negative, it indicates a decrease relative to the original data.
[0137] As shown in Table 7, compared to the base group (left cheek treated with the base essence from Formula 2 of Example 1), the experimental group (right cheek treated with the essence from Example 3) showed a significant increase in both elasticity R2 and elasticity R5, indicating improved skin elasticity. Compared to the base group, the experimental group also showed a significant increase in collagen and moisture content. Furthermore, compared to the base group, the experimental group showed a significant decrease in the proportion of crow's feet and nasolabial folds, and a substantial increase in scores for crow's feet, nasolabial folds, and skin texture, demonstrating a significant improvement in anti-wrinkle and wrinkle-reducing effects.
[0138] The product is formulated with skin conditioning agents including bakuchiol, thermophilic bacteria ferment filtrate, collagen, and magnolia flower extract, combined with other components in the anti-aging and lifting skincare essence. This synergistic effect enables deep repair, antioxidant defense, collagen regeneration promotion, and long-lasting hydration, comprehensively improving the skin's internal health and external radiance.
[0139] In summary, the embodiments of the present invention first provide a basic ingredient for an anti-aging and lifting skincare essence, which can achieve multiple skincare goals such as deep penetration, long-lasting moisturizing, and anti-wrinkle and firming. It achieves anti-wrinkle and brightening (essence one corresponding to embodiment 2), firming and lifting (essence two corresponding to embodiment 3), and anti-wrinkle and wrinkle reduction (essence three corresponding to embodiment 4) through different skin conditioning agents, thereby accurately covering and effectively integrating the complex needs of consumers and ensuring comprehensive skincare effects.
[0140] The above provides a detailed description of an anti-aging and lifting skincare essence, its preparation method, and its application, as provided in the embodiments of the present invention. Specific examples have been used to illustrate the principles and implementation methods of the present invention. The descriptions of the above embodiments are only for the purpose of helping to understand the method and core ideas of the present invention. At the same time, for those skilled in the art, there will be changes in the specific implementation methods and application scope based on the ideas of the present invention. Therefore, the content of this specification should not be construed as a limitation of the present invention.
Claims
1. An anti-aging and lifting skincare essence, characterized in that, By weight, it comprises the following components: 0.01-6 parts sodium hyaluronate, 1-30 parts moisturizer, 0.1-1 part antioxidant, 0.01-1 part pH adjuster, 0.01-0.1 part chelating agent, 1-10 parts skin conditioning agent, and 50-85 parts water.
2. The anti-aging and lifting skincare essence according to claim 1, characterized in that, The sodium hyaluronate includes at least one of sodium hyaluronate with a molecular weight of 800-1500 kDa, sodium hyaluronate with a molecular weight of 10-1000 kDa, sodium hyaluronate with a molecular weight of 2-8 kDa, acetylated sodium hyaluronate, and cross-linked sodium hyaluronate. And / or, the moisturizer includes at least one of glycerin, 1,3-propylene glycol, 1,2-propylene glycol, dipropylene glycol, butylene glycol, 1,2-pentanediol, methyl gluceth-20, 1,2-hexanediol, and 2,3-butanediol; And / or, the antioxidant includes at least one of p-hydroxyacetophenone, tocopherol, and ergothioneine; And / or, the pH adjuster includes at least one of sodium hydroxide, potassium hydroxide, arginine, triethanolamine, citric acid, and sodium citrate; And / or, the chelating agent includes at least one of sodium phytate, gluconolactone, and disodium EDTA.
3. The anti-aging and lifting skincare essence according to claim 2, characterized in that, By weight, the sodium hyaluronate comprises 0.01-1 parts of sodium hyaluronate with a molecular weight of 800-1500 kDa, 0.01-2 parts of sodium hyaluronate with a molecular weight of 10-1000 kDa, and 0.01-3 parts of sodium hyaluronate with a molecular weight of 2-8 kDa. And / or, by weight, the humectant comprises 1-5 parts of butylene glycol and 0.1-5 parts of 1,2-hexanediol; And / or, the antioxidant is p-hydroxyacetophenone; And / or, by weight, the pH adjuster comprises 0.001-0.1 parts arginine and 0.001-0.1 parts citric acid; And / or, the chelating agent is disodium ethylenediaminetetraacetate.
4. The anti-aging and lifting skincare essence according to any one of claims 1-3, characterized in that, The skin conditioning agent includes niacinamide, Ganoderma lucidum extract, and complex peptides; The composite polypeptide includes dipeptide diaminobutyryl benzylamide diacetate, acetyl hexapeptide-8, palmitoyl pentapeptide-5, and arginine / lysine polypeptide.
5. The anti-aging and lifting skincare essence according to claim 4, characterized in that, The skin conditioning agent also includes daisy flower extract, sodium mannose phosphate, and soursop fruit extract.
6. The anti-aging and lifting skincare essence according to claim 5, characterized in that, The skin conditioning agent comprises, by weight, 1-5 parts niacinamide, 0.01-1 parts daisy extract, 0.01-1 parts Ganoderma lucidum extract, 0.01-1 parts complex polypeptide, 0.01-1 parts sodium mannose phosphate, and 0.01-1 parts custard apple fruit extract.
7. The anti-aging and lifting skincare essence according to any one of claims 1-3, characterized in that, The skin conditioning agent includes caffeine and ascorbic acid peptides.
8. The anti-aging and lifting skincare essence according to claim 7, characterized in that, The skin conditioning agent also includes niacinamide and quinoa seed extract; And / or, the ascorbic acid polypeptide is a stable vitamin C derivative.
9. The anti-aging and lifting skincare essence according to claim 8, characterized in that, The skin conditioning agent comprises, by weight, 1-5 parts niacinamide, 0.01-1 parts ascorbic acid polypeptide, and 0.01-1 parts quinoa seed extract.
10. The anti-aging and lifting skincare essence according to any one of claims 1-3, characterized in that, The skin conditioning agent includes bakuchiol, thermophilic bacteria fermentation products, and collagen.
11. The anti-aging and lifting skincare essence according to claim 10, characterized in that, The skin conditioning agent also includes magnolia flower extract.
12. The anti-aging and lifting skincare essence according to claim 11, characterized in that, The skin conditioning agent comprises, by weight, 0.01-1 parts of thermophilic bacteria fermentation product, 0.01-1 parts of magnolia flower extract, and 0.00001-0.1 parts of collagen.
13. A method for preparing an anti-aging and lifting skincare essence, used to prepare the anti-aging and lifting skincare essence as described in any one of claims 1-12, characterized in that, include: Add water to an emulsification pot, then add sodium hyaluronate, humectant, antioxidant, pH adjuster, and chelating agent to the emulsification pot, heat to 80-85℃ and stir to obtain the first mixture; The first mixture is cooled to 40-45°C, and then a skin conditioning agent is added and mixed to obtain the second mixture. The second mixture is cooled to 30-35℃ to obtain an anti-aging and lifting skincare essence.
14. The use of the anti-aging and lifting skincare essence according to any one of claims 1-12 in skincare products.