Microwave hyperthermia device for noninvasive measurement of temperature of tumor body

Abstract

The embodiment of the invention provides a microwave hyperthermia device for noninvasive measurement of tumor body temperature, and the device comprises a solid-state microwave source, and the bottom of one end of the solid-state microwave source is provided with a connector in an embedded manner; the microwave conduction device is fixedly installed in the connector, a treatment application device is installed at the bottom end of the microwave conduction device, and the treatment application device is connected with the solid-state microwave source through the microwave conduction device and the connector; the detection frame is fixedly mounted on one side of the solid-state microwave source, a plurality of microwave imaging devices are mounted in the detection frame, each microwave imaging device comprises a mounting seat, a microwave emission head and a receiving probe, the mounting seat is fixedly mounted in the detection frame, the microwave emission head is mounted at one end of the mounting seat in an embedded manner, and the receiving probe is mounted at the other end of the mounting seat. The microwave imaging device is adopted to carry out non-contact imaging scanning and temperature measurement on a focus, temperature distribution data images of the surface and the interior of a tumor are directly obtained, and accurate tumor positioning is achieved by fusing the temperature distribution data images with CT and nuclear magnetic resonance examination results.

Description

Technical Field

[0001] This application relates to the field of medical device technology, specifically to a non-invasive microwave hyperthermia device for measuring the temperature of a tumor. Background Technology

[0002] Microwave irradiation produces a thermal effect on living organisms, and the high temperature can directly kill tumor cells. Therefore, microwave thermotherapy is commonly used to treat tumors. The reason why microwave irradiation produces a microwave biological effect is that various tissues in the human body have inherent frequencies. When the microwave frequency is the same as the inherent frequency of a certain tissue, the tissue will resonate and absorb the energy. When the energy absorbed by the tissue exceeds a certain threshold, a biological effect will be caused. Thermotherapy not only plays a significant role in the treatment of malignant tumors, but also has remarkable effects in the treatment of many benign diseases. It has shown great development potential and broad application prospects in clinical applications, benefiting a large number of patients. The temperature of microwave thermotherapy is 42-45℃, with an error of ±0.3℃. Current microwave hyperthermia systems, when heating diseased tissues in the human body, mostly require manual movement of the temperature probe inside the temperature measuring component to the skin outside the diseased tissue. External force is also required to press the temperature probe into the skin, so that the measured temperature is close to the actual temperature of the diseased tissue. However, the measured value is not the actual temperature value of the diseased tissue, making it difficult for microwave hyperthermia to achieve precise treatment. The temperature probe in the aforementioned microwave thermotherapy device can cause pain or even damage to the skin when pressed against it, resulting in a poor user experience. Summary of the Invention

[0003] This application provides a non-invasive microwave hyperthermia device for measuring the temperature of a tumor, thereby addressing one of the aforementioned technical deficiencies.

[0004] To achieve the above objectives, this application provides the following technical solution: a non-invasive microwave thermotherapy device for measuring the temperature of a tumor, comprising: a solid-state microwave source, wherein a connector is embedded at the bottom of one end of the solid-state microwave source; The microwave conduction device is fixedly installed inside the connector, and a treatment applicator is installed at its bottom. The treatment applicator is connected to the solid-state microwave source through the microwave conduction device and the connector. The detector frame is fixedly installed on one side of the solid-state microwave source. Multiple microwave imaging devices are installed inside the detector frame. Each microwave imaging device includes a mounting base, a microwave transmitter head and a receiving probe. The mounting base is fixedly installed inside the detector frame. The microwave transmitter head is embedded in one end of the mounting base and the receiving probe is installed at one end of the mounting base and located below the microwave transmitter head. The positioning component, installed inside the treatment applicator, has a first operating state and a second operating state: In the first working state, the positioning component moves upward and is fixedly connected to the microwave imaging device on the detection frame; In the second working state, the positioning component moves downward to maintain a distance from the patient's skin.

[0005] In any of the above technical solutions, the positioning component further includes: The snap-fit ​​ring is vertically and movable inside the treatment applicator; The suction cup is attached to the inner wall of the snap ring; Two triangular plates are symmetrically and integrally molded at the bottom of the snap ring and located inside the treatment applicator. A concave rod is fitted to the bottom of a triangular plate, and the top of the end face of the concave rod near the triangular plate is set as an inclined surface; Push plate one is installed on one end face of the concave rod, and the bottom of the end face of push plate one near the triangular plate is set as an inclined surface; The placement groove is located inside the concave rod, and wavy recesses are provided at equal intervals at the top and bottom of the placement groove. The barrier block is fixedly installed inside the treatment applicator. The top and bottom of the barrier block are equally spaced wavy protrusions that match the depressions.

[0006] In any of the above technical solutions, the positioning component further includes: Two connecting strips are attached to the bottom of the concave rod. Push plate two is fixedly installed on one end face of the connecting strip; An L-shaped strip is fixedly installed at the bottom end of the connecting strip; A rectangular plate is disposed between the second push plate and the L-shaped strip. The top edge of the L-shaped strip facing the second push plate is set as an inclined surface, and the top edge of the second push plate facing the rectangular plate is set as an inclined surface. A support ring is connected to the bottom ends of the two rectangular plates, and a groove is provided in the middle of the bottom end of the inner wall of the support ring.

[0007] In any of the above technical solutions, the positioning component further includes: Magnetic pads are embedded in the grooves of the support ring; The magnetic strip is attached to the bottom of the magnetic pad. A raised ring is fixedly installed at the bottom end of the magnetic plate; An adhesive sheet is bonded to the bottom of the convex ring. The negative film is attached to the bottom of the adhesive film.

[0008] In any of the above technical solutions, the suction cup is made of medical-grade silicone rubber, the adhesive sheet is made of medical pressure-sensitive tape coated on a non-woven fabric substrate, and the backing film is made of PET film.

[0009] In any of the above technical solutions, the wave-shaped recess of the placement groove and the wave-shaped protrusion of the barrier block form a multi-level engagement structure, which is used to provide graded damping and positioning feedback when the positioning component moves.

[0010] In any of the above technical solutions, the bottom end of the triangular plate and the inclined surface of the top end of the concave rod cooperate with each other, and the inclined surface of the bottom end of the triangular plate push plate one cooperates to form an inclined surface transmission mechanism, which is used to convert the lateral movement into the vertical movement. The inclined surface of the top end of the rectangular plate and the L-shaped strip cooperate with each other, and the inclined surface of the top end of the rectangular plate and the push plate two cooperate with each other to form an inclined surface transmission mechanism, which is used to convert the lateral movement into the vertical movement.

[0011] In any of the above technical solutions, the adsorption force between the magnetic pad and the magnetic sheet is less than the adhesion force between the adhesive sheet and the patient's skin.

[0012] In any of the above technical solutions, the number of microwave imaging devices is twelve, which are equidistantly distributed along the inner edge of the probe frame. Each microwave imaging device has a microwave transmitter head and a receiver probe that form a pair, which are used to perform multi-angle imaging scanning and temperature measurement on the lesion (tumor) area.

[0013] In any of the above technical solutions, a treatment chair is further included, which is located in the middle area of ​​the probe frame, and the patient can receive treatment in a sitting, lying, or supine position on the treatment chair.

[0014] The microwave hyperthermia device for non-invasive measurement of tumor temperature provided in this application embodiment has the following technical advantages compared to the prior art: This invention uses a microwave imaging device to perform non-contact imaging scanning and temperature measurement on lesions, directly acquiring temperature distribution data images of the tumor surface and interior, and achieving precise tumor localization by fusing with CT and MRI examination results.

[0015] It should be understood that both the foregoing general description and the following detailed description are for illustrative purposes and do not necessarily limit the scope of this disclosure. The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate the subject matter of this disclosure. Furthermore, the specification and drawings serve to explain the principles of this disclosure. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the specific embodiments of this disclosure or the prior art, the accompanying drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this disclosure. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. The illustrative embodiments of this application and their descriptions are used to explain this application and do not constitute an improper limitation of this application.

[0017] Figure 1 This is a schematic diagram of the structure of an embodiment of the present disclosure; Figure 2 For this disclosure Figure 1 Schematic diagram of the structure of region A in the middle; Figure 3 This is a schematic diagram of the positioning component in an embodiment of the present disclosure; Figure 4 This is a schematic diagram of the mounting structure of the pusher plate in an embodiment of this disclosure; Figure 5 This is a schematic diagram of the support ring mounting structure in an embodiment of this disclosure; Figure 6 For this disclosure Figure 5 A schematic diagram of the structure of region B in the middle.

[0018] Icons: 1. Solid-state microwave source; 2. Connector; 3. Microwave conduction device; 4. Treatment applicator; 5. Detector frame; 6. Positioning component; 61. Snap ring; 62. Suction cup; 63. Triangular plate; 64. Concave rod; 65. Push plate one; 66. Placement slot; 67. Barrier block; 68. Connecting strip; 69. Push plate two; 610. Rectangular plate; 611. Support ring; 612. Magnetic pad; 613. Magnetic sheet; 614. Convex ring; 615. Adhesive sheet; 616. Film; 617. L-shaped strip; 7. Treatment chair; 8. Microwave imaging device; 81. Mounting base; 82. Microwave transmitter head; 83. Receiver probe. Detailed Implementation

[0019] This invention discloses a non-invasive microwave thermotherapy device for measuring tumor temperature, which solves the problem that existing temperature probes cause pain or even skin damage when pressed against the skin, resulting in a poor user experience.

[0020] To make the technical solutions and advantages of the embodiments of this application clearer, the exemplary embodiments of this application will be described in further detail below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not an exhaustive list of all embodiments. It should be noted that, unless otherwise specified, the embodiments and features in the embodiments of this application can be combined with each other.

[0021] Please see Figures 1-6 A non-invasive microwave thermotherapy device for measuring the temperature of a tumor includes: a solid-state microwave source 1, a connector 2 embedded at the bottom of one end of the solid-state microwave source 1, a microwave conduction device 3 fixedly installed inside the connector 2, the microwave conduction device 3 being a cable, a treatment applicator 4 installed at the bottom of the microwave conduction device 3, the treatment applicator 4 being a treatment head, and the treatment applicator 4 being connected to the solid-state microwave source 1 through the microwave conduction device 3 and the connector 2. A detector frame 5 is fixedly installed on one side of the solid-state microwave source 1. The detector frame 5 is circular in shape. Twelve microwave imaging devices 8 are equidistantly installed in the circumference of the detector frame 5. Each microwave imaging device 8 includes a mounting base 81 fixedly installed inside the solid-state microwave source 1. A microwave transmitter head 82 is embedded in one end of the mounting base 81. A receiver probe 83 is installed at the other end of the mounting base 81 below the microwave transmitter head 82. A treatment chair 7 is set in the middle of the detector frame 5. Patients can receive treatment in a sitting, lying, or supine position on the treatment chair 7. The treatment applicator 4 has a positioning component 6 installed inside. The positioning component 6 moves upward and is fixedly connected to the microwave imaging device 8 on the probe frame 5. The positioning component 6 moves downward and separates from the microwave imaging device 8, and maintains a constant distance from the patient's skin.

[0022] In use, the patient enters the treatment chair 7 through the interior of the circular probe frame 5, and then receives treatment in a sitting, lying, or supine position. Medical staff adjust the patient to a comfortable and treatment-friendly posture using the adjustment mechanism of the treatment chair 7 (this adjustment mechanism is existing technology and will not be elaborated upon here). Next, the microwave imaging device 8 is activated, and a preliminary scan of the lesion (tumor) area is performed using twelve pairs of microwave transmitters 82 and receiver probes 83 (the microwave transmitters 82 emit low-power microwave imaging signals for imaging and temperature measurement of the lesion (tumor) tissue). Then, the low-power microwave imaging signal is received by the receiving probe 83, and after data processing, a microwave grayscale image of the lesion (tumor) is obtained. This image is fused with the patient's preoperative CT and MRI examination results to generate accurate three-dimensional positioning information of the lesion (tumor), which is displayed on the screen of the control system. Then, the positioning component 6 is pushed, so that the positioning component 6 is separated from the treatment applicator 4 after operation. Then, the medical staff puts the treatment applicator 4 into the lesion (tumor) site of the patient. The medical staff starts the solid-state microwave source 1 through the control system. The solid-state microwave source 1 generates therapeutic microwave energy ( The frequency is typically 915MHz or 2450Hz, and the power is adjusted according to the size and depth of the lesion. This energy is transmitted to the treatment applicator 4 via connector 2 and microwave conduction device 3. The treatment applicator 4 radiates microwave energy to the patient's lesion (tumor) site, heating the lesion (tumor) tissue. When microwaves irradiate biological tissue, due to the difference in dielectric properties between the lesion (tumor) tissue and normal tissue, the lesion (tumor) tissue resonates and absorbs the microwaves, causing the temperature to rise. Simultaneously with the treatment, the microwave imaging device 8 on the detector 5 continues to operate, with twelve pairs of microwave transmitters 82 directed towards the lesion (tumor) area. The system emits a low-power microwave detection signal (milliwatt level, no thermal effect), and the receiving probe 83 receives the signal after it has been reflected and transmitted through the tissue. The control system calculates the temperature distribution data image of the lesion (tumor) surface and interior in real time based on the grayscale changes of the received signal. This temperature data is seamlessly transmitted to the microwave power control system via Bluetooth communication module and compared with the preset temperature value (42-45℃±0.3℃). (The above control system belongs to the prior art and will not be elaborated on here.) When the temperature decreases, the output power is increased. After the treatment time reaches the preset value, the control system automatically stops the microwave output of the solid-state microwave source 1.

[0023] Current microwave thermotherapy systems, when heating diseased tissues in the human body, mostly require manual movement of the temperature probe within the temperature measuring component onto the skin outside the diseased tissue. External force is also needed to press the probe into the skin, causing it to be embedded. This results in a temperature reading that approximates the true temperature of the diseased tissue, but the measured value is not the actual temperature of the diseased tissue. This makes precise treatment difficult with microwave thermotherapy. Furthermore, the pressure of the temperature probe on the skin in these devices can cause pain and even damage, leading to a poor user experience.

[0024] This invention uses a microwave imaging device 8 to perform non-contact imaging scanning and temperature measurement on lesions (tumors), directly acquiring temperature distribution data images of the surface and interior of the lesions (tumors), and achieving precise lesion (tumor) localization by fusing with CT and MRI examination results.

[0025] In a specific implementation of a non-invasive microwave hyperthermia device for measuring the temperature of a tumor, such as... Figure 3 and Figure 4 As shown, the positioning component 6 includes a vertically movable locking ring 61 inside the treatment applicator 4. The top of the treatment applicator 4 has a circular groove for placing the locking ring 61. The inner wall of the locking ring 61 has an angled edge, and a suction cup 62 is attached to the angled edge. A triangular plate 63 is symmetrically and integrally formed inside the treatment applicator 4 at the bottom of the locking ring 61. A rectangular groove is formed in the middle of the triangular plate 63, and a concave rod 64 is attached to the bottom of the triangular plate 63. A guide groove for the lateral movement of the concave rod 64 is provided inside the treatment applicator 4. A push plate 65 is installed on one end face of the concave rod 64. The top of the end face of the concave rod 64 near the triangular plate 63 is set as an inclined surface, and the bottom of the push plate 65 near the end face of the triangular plate 63... The triangular plate 63 is set as an inclined surface, and the inclined surface of the bottom end of the triangular plate 63 and the top end of the concave rod 64 cooperate with each other. The inclined surface of the bottom end of the triangular plate 63 pushes the inclined surface of the bottom end of the push plate 65 to form an inclined surface transmission mechanism, which is used to convert the horizontal movement into the vertical movement. The push plate 65 is located inside the rectangular hole of the triangular plate 63 and fits against it. The top of the end face of the concave rod 64 near the triangular plate 63 is on an inclined surface, and the bottom of the end face of the push plate 65 near the triangular plate 63 is on an inclined surface. The concave rod 64 has a placement groove 66 inside. The top and bottom ends of the placement groove 66 are equally spaced with wave-shaped depressions. The treatment applicator 4 has a blocking block 67 fixedly installed inside. The top and bottom ends of the blocking block 67 are equally spaced with wave-shaped protrusions, and the protrusions and depressions match. The concave rod 64, triangular plate 63, push plate 65, and blocking block 67 are all made of medical-grade stainless steel or polyoxymethylene (POM) material, which has good wear resistance and biocompatibility, ensuring transmission accuracy and tactile stability during long-term use.

[0026] In use, the concave rod 64 is pushed to move along the horizontal plane. As the concave rod 64 moves along the outside of the blocking block 67, a multi-level engagement structure is formed between the wavy protrusions at the top and bottom of the blocking block 67 and the wavy recesses at the top and bottom of the placement groove 66. This structure provides graded damping and positioning feedback when the concave rod 64 moves. As the concave rod 64 moves, it synchronously drives the push plate 65 to move. When the concave rod 64 moves toward the inclined surface of the concave rod 64, it drives the triangular plate 63 to rise through its engagement with the inclined surface of the triangular plate 63. When the triangular plate 63 rises, it drives the locking ring 61 and the suction cup 62 to rise, exposing the locking ring 61 and the suction cup 62 from the inside of the circular groove. Then, the locking ring 61 is locked to the outside of the mounting base 81, and then the suction cup 62 is used to attach and fix the structure, thereby keeping the treatment applicator 4 stable during placement and preventing swaying during placement. The snap-fit ​​between the snap-fit ​​ring 61 and the mounting base 81 adopts a tapered self-locking structure, and there is no radial or axial wobble after snap-fit. Conversely, pushing the concave rod 64 in the opposite direction separates the inclined surface of the concave rod 64 from the inclined surface of the triangular plate 63. At the same time, the inclined surface of the pushing plate 65 pushes the triangular plate 63 down, allowing the triangular plate 63 to enter the treatment applicator 4 for storage. This saves space and reduces interference from the external environment, thereby increasing usage time. Furthermore, the multi-level interlocking structure formed by the wavy protrusions and wavy recesses provides fixation and prevents self-movement.

[0027] In a specific implementation of a non-invasive microwave hyperthermia device for measuring the temperature of a tumor, such as... Figure 3 and Figure 4 As shown, the bottom end of the concave rod 64 is connected to two connecting strips 68. A push plate 69 is fixedly installed on one end face of the connecting strip 68. An L-shaped strip 617 is fixedly installed on the bottom end of each of the two connecting strips 68. A rectangular plate 610 is provided between the push plate 69 and the L-shaped strip 617. A square hole is opened in the middle of the rectangular plate 610. The top edge of the push plate 69 facing the rectangular plate 610 is set as an inclined surface. The push plate 69 is located inside the square hole and fits against it. An inclined surface is opened on the top of one end face of the L-shaped strip 617. The inclined surface of the L-shaped strip 617 cooperates with the push plate 69 through the square hole. The inclined surface at the top of the push plate 69 cooperates with the rectangular plate 610 to form an inclined plane transmission mechanism, which is used to convert the horizontal movement into the vertical movement. The bottom ends of the two rectangular plates 610 are connected to the same support ring 611.

[0028] In use, when the concave rod 64 moves, it simultaneously drives the two connecting bars 68 to move in the same direction. At this time, the connecting bars 68 drive the L-shaped bar 617 and the second push plate 69 to move synchronously. At the same time, the inclined surface of the L-shaped bar 617 cooperates with the second push plate 69 to drive the second push plate 69 to rise. When the second push plate 69 rises, it drives the support ring 611, so that the support ring 611 enters the bottom of the inner wall of the treatment applicator 4, thereby hiding the position of the support ring 611 and keeping the bottom of the treatment applicator 4 flat. As described above, the support ring 611 and the locking ring 61 rise and fall together, reducing the difficulty of operation and achieving the purpose of driving two objects to move synchronously in one step.

[0029] In a specific implementation of a non-invasive microwave hyperthermia device for measuring the temperature of a tumor, such as... Figure 3 and Figure 4 As shown, a groove is provided in the middle of the bottom end of the inner wall of the support ring 611. A magnetic pad 612 is embedded in the groove of the support ring 611. A magnetic sheet 613 is attached to the bottom end of the magnetic pad 612. A convex ring 614 is fixedly installed at the bottom end of the magnetic sheet 613. An adhesive sheet 615 is bonded to the bottom end of the convex ring 614. A base sheet 616 is bonded to the bottom end of the adhesive sheet 615. The suction cup 62 is made of medical-grade silicone rubber. The adhesive sheet 615 is made of medical pressure-sensitive tape coated on a non-woven fabric substrate. The base sheet 616 is made of PET film. The magnetic pad 612 is made of neodymium iron boron (NdFeB) permanent magnet material embedded in a medical-grade silicone matrix. The magnetic sheet 613 is made of pure iron or low carbon steel and is nickel-plated on the surface, which has good magnetic conductivity and rust prevention properties.

[0030] The user tears open the backing film 616, exposing the adhesive sheet 615. The user then places the treatment applicator 4 at the patient's lesion (tumor). The adhesive sheet 615 adheres to the patient. When the position needs adjustment or the adhesive sheet 615 needs replacement to prevent cross-interference, the attraction between the magnetic pad 612 and the magnetic sheet 613 is less than the adhesion between the adhesive sheet 615 and the patient's skin. The user simply lifts the treatment applicator 4 upwards, causing the magnetic sheet 613 to separate from the magnetic pad 612. After separation, the adhesive sheet 615 adheres to the patient's skin. Finally, the medical staff can remove it, thus achieving the purpose of single-use and changing the existing technology that requires prolonged handling by medical staff. This method reduces the handling time for medical staff.

[0031] Workflow: The patient enters through the circular probe frame 5 and sits on the treatment chair 7. Medical staff adjust the patient to a comfortable and treatment-friendly position (sitting, lying, or reclining) using the adjustment mechanism of the treatment chair 7, according to the location of the lesion and treatment needs (the treatment chair adjustment mechanism is existing technology). The microwave imaging device 8 is activated, and twelve pairs of microwave transmitters 82 transmit low-power microwave imaging signals (milliwatt level, frequency 1-10GHz) to the lesion (tumor) area. The receiving probe 83 receives the signals after tissue reflection and transmission. The control system processes the received signals to generate a microwave grayscale image of the lesion (tumor). The image is fused with the patient's preoperative CT and MRI results to generate precise three-dimensional localization information of the lesion (tumor), which is then displayed on the control system's screen. The fused image contains both anatomical structure information and real-time temperature distribution data, providing precise navigation for subsequent treatment. Next, the medical staff peeled off the bottom film 616 (PET release film) of the adhesive sheet 615 to expose the medical pressure-sensitive adhesive layer of the adhesive sheet 615, in preparation for placing the treatment applicator 4 on the patient's lesion site. Medical staff hold the treatment app 4 and move it to the surface projection area of ​​the patient's lesion site according to the fusion positioning information on the display screen. Then, they push the concave rod 64 forward, causing the concave rod 64 to move forward along the horizontal guide groove. When the concave rod 64 moves, the wave-shaped indentations at the top and bottom of the placement groove 66 inside it form a multi-level engagement structure with the wave-shaped protrusions at the top and bottom of the blocking block 67 fixed inside the treatment applicator 4, which provides clear feedback without causing laborious operation. The inclined surface at the front end of the concave rod 64 cooperates with the inclined surface at the bottom end of the triangular plate 63 to form an inclined plane transmission mechanism, which converts the horizontal movement of the concave rod 64 into the vertical descent of the triangular plate 63. The triangular plate 63 drives the locking ring 61 and the suction cup 62 to descend from the circular groove at the top of the treatment applicator 4. When the locking ring 61 descends to the lowest position, it completely separates from the outside of the mounting seat 81 on the probe frame 5 and enters the interior of the treatment applicator 4. Conversely, it is fixed to the mounting seat 81 by a cone, so that there is no wobbling in the radial and axial directions. At the same time, the suction cup 62 contacts and adheres to the surface of the mounting seat 81, providing double fixation protection. As the concave rod 64 moves, it drives the L-shaped rod 617 and the second push plate 69 to move horizontally synchronously via the connecting rod 68. The inclined surface of the L-shaped rod 617 engages with the second push plate 69, and the inclined surface of the second push plate 69 engages with the rectangular plate 610, forming a second set of inclined plane transmission mechanisms. This converts the horizontal movement into the vertical descent of the rectangular plate 610 and the support ring 611, and vice versa. The support ring 611 descends to the outside of the bottom of the treatment applicator 4, so that the magnetic pad 612, magnetic sheet 613, convex ring 614 and adhesive sheet 615 at its bottom are close to the patient's skin. When the support ring 611 descends to the point where the adhesive patch 615 contacts the patient's skin, the medical staff observes the display screen to confirm that the radiation area of ​​the treatment applicator 4 coincides with the fusion-positioned lesion (tumor) area. Then, the medical staff gently continues to press down on the treatment applicator 4 to ensure that the adhesive patch 615 fully adheres to the skin. At the same time, the bottom of the treatment applicator 4 maintains a constant distance from the skin to achieve non-contact treatment. Then, the treatment applicator 4 is fixed by adsorption, which reduces the time required to remove it. When removing it, because the adsorption force between the adhesive patch 615 and the patient's skin is greater than the adsorption force between the magnetic pad 612 and the magnetic patch 613, the magnetic pad 612 and the magnetic patch 613 separate when the treatment applicator 4 is removed, causing the adhesive patch 615 to adhere to the patient's skin. Then, the treatment applicator 4 is fixed to the probe frame 5 by the snap ring 61. During treatment, medical staff activate the solid-state microwave source 1 through the control system. The solid-state microwave source 1 generates therapeutic microwave energy (frequency 915MHz or 2450Hz, power adjusted according to the size and depth of the lesion). This energy is transmitted sequentially through the connector 2 and the microwave conduction device 3 (coaxial cable) to the treatment applicator 4. The treatment applicator 4 radiates the microwave energy to the lesion site of the patient, heating the tumor tissue. When microwaves irradiate biological tissue, due to the difference in dielectric properties between tumor tissue and normal tissue (tumor tissue has high water content, higher dielectric constant and conductivity), the tumor tissue resonates and absorbs the microwaves, and its temperature rises preferentially, while the normal tissue heats up more slowly, thus achieving selective thermotherapy. While the treatment is underway, the microwave imaging device 8 on the probe 5 continues to operate. The microwave transmitter 82 emits low-power microwave detection signals (milliwatt level, frequency 1-10 GHz, no thermal effect) towards the lesion (tumor) area. The receiver probe 83 receives the signals after tissue reflection and transmission. The control system calculates the temperature distribution data image of the lesion (tumor) surface and interior in real time based on the grayscale change (or phase change) of the transmitted and received signals. The real-time temperature data is seamlessly transmitted to the microwave power control system via Bluetooth communication module and compared with the preset temperature value (42-45℃±0.3℃). When the measured temperature is lower than the set lower limit, the control system automatically increases the output power of the solid-state microwave source 1. When the measured temperature is higher than the set upper limit, the control system automatically decreases the output power of the solid-state microwave source 1. When the temperature is within the set range, the current power is maintained. When the treatment time reaches the preset value, the control system automatically stops the microwave output of the solid-state microwave source 1, and at this time the treatment applicator 4 no longer radiates energy.

[0032] Based on the embodiments in this disclosure, all other embodiments obtained by those skilled in the art without inventive effort are within the scope of protection of this disclosure.

[0033] In the description of this disclosure, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this disclosure and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this disclosure. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0034] In the description of this disclosure, it should be noted that, unless otherwise expressly specified and limited, the terms "installation," "connection," and "linkage" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection between two components. Those skilled in the art can understand the specific meaning of the above terms in this disclosure based on the specific circumstances.

[0035] Although preferred embodiments of this application have been described, those skilled in the art, upon learning the basic inventive concept, can make other changes and modifications to these embodiments. Therefore, the appended claims are intended to be interpreted as including the preferred embodiments as well as all changes and modifications falling within the scope of this application.

[0036] Obviously, those skilled in the art can make various modifications and variations to this application without departing from the spirit and scope of this application. Therefore, if such modifications and variations fall within the scope of the claims of this application and their equivalents, this application also intends to include such modifications and variations.

Claims

1. A non-invasive microwave hyperthermia device for measuring the temperature of a tumor, characterized in that, include: Solid-state microwave source (1), with a connector (2) embedded at the bottom of one end of the solid-state microwave source (1). A microwave conduction device (3) is fixedly installed inside the connector (2), and a treatment applicator (4) is installed at its bottom end. The treatment applicator (4) is connected to the solid-state microwave source (1) through the microwave conduction device (3) and the connector (2). The detector frame (5) is fixedly installed on one side of the solid-state microwave source (1). Multiple microwave imaging devices (8) are installed inside the detector frame (5). Each microwave imaging device (8) includes a mounting base (81), a microwave transmitter (82), and a receiving probe (83). The mounting base (81) is fixedly installed inside the detector frame (5). The microwave transmitter (82) is embedded in one end of the mounting base (81). The receiving probe (83) is installed at one end of the mounting base (81) and located below the microwave transmitter (82). A positioning component (6) is installed inside the treatment applicator (4), and the positioning component (6) has a first working state and a second working state: In the first working state, the positioning component (6) moves upward and is fixedly connected to the microwave imaging device (8) on the detection frame (5); In the second working state, the positioning component (6) moves downward to maintain a distance from the patient's skin.

2. The microwave hyperthermia device for non-invasive measurement of tumor temperature according to claim 1, characterized in that, The positioning component (6) includes: The snap ring (61) is vertically movable inside the treatment applicator (4); The suction cup (62) is attached to the inner wall of the snap ring (61); Two triangular plates (63) are symmetrically and integrally formed at the bottom end of the snap ring (61) and located inside the treatment applicator (4); A concave rod (64) is attached to the bottom end of the triangular plate (63), and the top of one end face of the concave rod (64) near the triangular plate (63) is set as an inclined surface; Push plate 1 (65) is installed on one end face of the concave rod (64), and the bottom of the end face of push plate 1 (65) near the triangular plate (63) is set as an inclined surface; The placement groove (66) is opened inside the concave rod (64), and the top and bottom ends of the placement groove (66) are provided with wavy recesses at equal intervals; The barrier block (67) is fixedly installed inside the treatment applicator (4). The top and bottom ends of the barrier block (67) are provided with wavy protrusions at equal intervals, and the protrusions match the depressions.

3. The microwave hyperthermia device for non-invasive measurement of tumor temperature according to claim 2, characterized in that, The positioning component (6) further includes: Two connecting strips (68) are attached to the bottom end of the concave rod (64); Push plate 2 (69) is fixedly installed on one end face of the connecting strip (68); L-shaped strip (617) is fixedly installed at the bottom end of the connecting strip (68); A rectangular plate (610) is disposed between the second push plate (69) and the L-shaped strip (617). The top edge of the L-shaped strip (617) facing the second push plate (69) is set as an inclined surface, and the top edge of the second push plate (69) facing the rectangular plate (610) is set as an inclined surface. A support ring (611) is connected to the bottom of the two rectangular plates (610), and a groove is provided in the middle of the bottom of the inner wall of the support ring (611).

4. The microwave hyperthermia device for non-invasive measurement of tumor temperature according to claim 3, characterized in that, The positioning component (6) further includes: A magnetic pad (612) is embedded in the groove of the support ring (611); A magnetic sheet (613) is attached to the bottom of the magnetic pad (612); A convex ring (614) is fixedly installed at the bottom end of the magnetic absorbing sheet (613); An adhesive sheet (615) is bonded to the bottom end of the protruding ring (614); The substrate (616) is bonded to the bottom end of the adhesive sheet (615).

5. A non-invasive microwave hyperthermia device for measuring tumor temperature according to claim 4, characterized in that, The suction cup (62) is made of medical-grade silicone rubber, the adhesive sheet (615) is made of medical pressure-sensitive tape coated on a non-woven fabric substrate, and the substrate (616) is made of PET film.

6. The microwave hyperthermia device for non-invasive measurement of tumor temperature according to claim 2, characterized in that, The wave-shaped recess of the placement groove (66) and the wave-shaped protrusion of the blocking block (67) form a multi-level engagement structure, which provides graded damping and positioning feedback when the positioning component (6) moves.

7. The microwave hyperthermia device for non-invasive measurement of tumor temperature according to claim 3, characterized in that, The bottom end of the triangular plate (63) and the inclined surface of the top end of the concave rod (64) cooperate with each other. The bottom end of the triangular plate (63) and the inclined surface of the bottom end of the push plate one (65) cooperate to form an inclined surface transmission mechanism, which is used to convert the horizontal movement into the vertical movement. The rectangular plate (610) and the inclined surface of the top end of the L-shaped strip (617) cooperate with each other. The rectangular plate (610) and the push plate two (69) and the inclined surface of the top end cooperate to form an inclined surface transmission mechanism, which is used to convert the horizontal movement into the vertical movement.

8. A non-invasive microwave hyperthermia device for measuring tumor temperature according to claim 4, characterized in that, The attraction force between the magnetic pad (612) and the magnetic sheet (613) is less than the adhesion force between the adhesive sheet (615) and the patient's skin.

9. A non-invasive microwave hyperthermia device for measuring tumor temperature according to claim 1, characterized in that, The number of microwave imaging devices (8) is twelve, which are equidistantly distributed along the inner edge of the detector frame (5). Each microwave imaging device (8) has a microwave transmitter (82) and a receiver probe (83) forming a pair, which are used to perform multi-angle imaging scanning and temperature measurement on the lesion (tumor) area.

10. A non-invasive microwave hyperthermia device for measuring tumor temperature according to claim 1, characterized in that, It also includes a treatment chair (7), which is located in the middle area of ​​the probe frame (5), and the patient can receive treatment in a sitting, lying or supine position on the treatment chair (7).

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