A silk protein composition for hair growth

Abstract

The application discloses a silk protein composition for hair growth, and belongs to the technical field of hair growth silk protein compositions. The composition comprises moisturizing agents, fragrance imparting agents, cationic surfactants, acidity adjusting agents, co-emulsifiers, preservatives, antioxidants, oily ingredients, trace ingredients, lauroylsarcosine sodium, cocoyl glutamic acid TEA salt, sodium lauroamphoacetate, sodium chloride, phenoxyethanol, sodium laurate, citric acid, allantoin, cocamide propyl betaine, hydroxybenzoic acid ester, nicotinamide and a silk protein solution. The application has the beneficial effect that the product contains proteins and amino acids, can supplement the required nutrients for damaged and fragile hair, can stimulate the cell proliferation of human head hair papilla cells and hair matrix cells, can make the head of people with thinning hair or baldness regenerate hair, and can prevent hair loss for people with normal hair.

Description

Technical Field

[0001] This invention relates to a silk protein composition for hair growth, belonging to the technical field of silk protein compositions for hair growth. Background Technology

[0002] Traditional hair growth agents, such as those with glyceryl pentadecanoate, adenosine, and minoxidil as main components, work by replenishing nutrients, promoting blood circulation, and improving scalp cells. Glyceryl pentadecanoate is generally considered an energy-supplying material, effective for hair follicles with low energy metabolism, but with poor results. Adenosine and minoxidil act on hair papilla cells, inducing the production of cell growth factors and activating hair follicle cells, but their hair growth effect is also poor. Traditional hair growth agents containing glyceryl pentadecanoate, adenosine, and minoxidil have not yielded satisfactory results, leading to a desire to develop a more effective hair growth composition. Summary of the Invention

[0003] The purpose of this invention is to provide a silk protein composition for hair growth that can regenerate hair on the scalp and has the effects of stopping hair loss and promoting hair growth.

[0004] To achieve the above objectives, the present invention provides a silk protein hair root activation composition. It comprises the following auxiliary agents and percentages: 1% moisturizer, 1% fragrance agent, 1% cationic surfactant, 1% co-emulsifier, 1% preservative, 1% antioxidant, 0.5% oily component, 0.5% acidity regulator, and 5% trace components, wherein the trace components include Sapindus mukorossi fruit extract, lauryl glucoside, and Citrus aurantium extract. Reticulata (Fructus Reticulatae) peel extract, sodium PCA, sodium lactate, arginine, aspartic acid, pyrrolidone carboxylic acid, glycine, alanine, serine, valine, proline, threonine, isoleucine, histidine, phenylalanine, sodium hyaluronate crosspolymer, sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed sodium hyaluronate, glycerin, butylene glycol, 1,2-hexanediol, ethylhexylglycerin, 1,2-pentanediol, potassium sorbate, and also includes the following substances and percentages: water 70%, sodium lauroyl sarcosinate 3%, TEA cocoyl glutamate 2%, sodium lauroyl amphoteric acid 2%, sodium chloride 1%, phenoxyethanol 1%, sodium laurylate 0.5%, citric acid 0.5%, allantoin 0.5%, cocamidopropyl betaine 2%, methylparaben 0.5%, silk protein solution 2%, nicotinamide 3%.

[0005] The aforementioned moisturizer is at least one of glycerin, propylene glycol, butylene glycol, panthenol, sorbitol, dipropylene glycol, hexanediol, isopropanol, xylitol, trimethylglycine, and polyethylene glycol; the aforementioned fragrance is a fragrance; the aforementioned antioxidant is at least one of Polygonum cuspidatum, tea, and rosemary; the aforementioned cationic surfactant is lauryltrimethylammonium chloride; the aforementioned oily component is at least one of vegetable oil, triglycerides, branched-chain fatty alcohols, branched-chain fatty acids, and dimethyl silicone oil, and the aforementioned vegetable oil is preferably ethoxylated vegetable oil; the aforementioned acidity regulator is citric acid or lactic acid; the aforementioned co-emulsifier is at least one of fatty alcohol, wax, and stearate, and the aforementioned fatty alcohol is preferably 16-18 alcohol; the aforementioned preservative is at least one of parabens, Kathon, ethylhexylglycerin, phenoxyethanol, IPBC, sodium benzoate, and benzyl alcohol.

[0006] The beneficial effects of this invention are as follows: This composition contains proteins and amino acids, which replenish the nutrients needed for damaged and fragile hair. It can stimulate the cell proliferation of hair papilla cells and hair matrix cells in the human scalp. In addition, the components complement and cooperate with each other. Hydrolyzed silk protein can coat the hair strands and interact strongly with the keratin in the hair strands, filling the protein in damaged hair and penetrating into the hair strands to replenish nutrients. Furthermore, since silk protein is composed of eighteen kinds of amino acids, it can promote hair growth. For people with thinning hair or baldness, it can promote hair regrowth; for people with normal hair, it can prevent hair loss. Detailed Implementation

[0007] The product of this invention is available in various forms, including liquid, paste, gel, foam, emulsion, and solid. Considering its effectiveness in promoting hair growth, liquid and gel forms are preferred. Its components have the effect of stimulating hair follicle matrix cells, and other ingredients have antibacterial and anti-inflammatory effects, thereby preventing hair loss and accelerating hair growth. The invention is described below with reference to specific embodiments. The term "product of this invention" as used below is an abbreviation for "trial product of this invention" or "a silk protein composition for hair growth."

[0008] 1. Preparation method of silk protein solution

[0009] The specific production process of silk fibroin solution includes the following steps: 1) Using a 0.4-6% sodium bicarbonate aqueous solution as a degumming agent, degumming silkworm cocoons under conditions of pH 8-11, hydrolysis temperature 50-80℃, and time 2-4 hours; after degumming, filtering is performed to obtain degummed hydrolysate and silk fibroin fibers; 2) The degummed hydrolysate is subjected to electrodialysis to remove the salt in the solution, and the process yields sericin hydrolysate and dialysis ion solution. The sericin hydrolysate is retained, and the dialysis ion solution will be used in the next preparation of sericin hydrolysate; 3) The silk obtained in step 1) is filtered... Silk fibroin fibers are dissolved in a neutral salt solution of calcium chloride or calcium hypochlorite at a temperature of 60-100℃ and a mass percentage of 30-60% to hydrolyze and obtain silk fibroin protein solution; 4) The hydrolyzed silk fibroin protein solution from step 3) is subjected to electrodialysis to remove ions from the solution, and the solution is circulated until the conductivity of the solution reaches 10-500 μS / cm to obtain a light yellow pure silk fibroin solution. The ion solution after electrodialysis can be recycled as the neutral salt solution in step 4); 5) The sericin hydrolysate from step 2) and the pure silk fibroin solution from step 4) are mixed evenly to obtain the silk fibroin solution.

[0010] 2. Preparation method of the product of the present invention. Before describing the preparation method, the meanings of phase A, phase B, and phase C mentioned below in this specification shall be explained. Phase A is formed by mixing the moisturizer, cationic surfactant, sodium lauroyl sarcosinate, TEA cocoyl glutamate, sodium lauroamphoacetate, sodium chloride, phenoxyethanol, sodium laurylate, citric acid, allantoin, cocamidopropyl betaine, methylparaben, silk fibroin, nicotinamide, and water. Phase B is formed by mixing the co-emulsifier, oily components, trace components, and silicone oil. Phase C is classified as hydrolyzed silk protein solution, preservative, fragrance, and acidity regulator.

[0011] The preparation method of the product of the present invention includes the following steps: (1) First, add each component of phase A to a water pot according to the mass ratio, and add each component of phase B to an oil pot according to the mass ratio and mix evenly, and heat them to 80-85℃ respectively; (2) 15-20% of phase A in the water pot is drawn into an emulsification pot, and phase B in the oil pot is drawn into the emulsification pot, and then homogenize for 5-10 minutes. During the homogenization process, the remaining material of phase A in the water pot is added step by step, and then vacuum stirring is maintained for 20 minutes; (3) Cool the mixture after vacuum stirring in step 2 to below 40℃, and then add silicone oil emulsion, hydrolyzed silk protein, preservative, fragrance and acidity regulator in phase C in sequence while stirring. After stirring and mixing evenly, cool to room temperature. After passing the test, the product of the present invention - "a silk protein composition for hair growth" is obtained. Its pH value is 4.5-7.0 when measured by dilution method at 25℃.

[0012] 3. Specific implementation method, trial on bald people.

[0013] (1) Li Moumou, male, 37 years old, doctor, bald, used the product of this invention on June 8, 2024. He used 15 ml of the product to wash his hair every day. On June 20, hair roots began to appear. On July 5, hair grew out and the length was 1 cm.

[0014] (2) Mr. Wei, male, 40 years old, bald, used the product of this invention on May 31, 2024. Every morning or afternoon, he took 15 ml of the preparation of this invention and applied it evenly to the bald area with his fingers, once a day, and washed it off with water after 20 minutes. On June 15, hair follicles began to appear, and on June 30, hair grew out with a length of 1.1 cm.

[0015] (3) Huang, a 36-year-old male radiologist at a certain Traditional Chinese Medicine hospital, worked night shifts every other day for a long time. His irregular work and rest schedule and insomnia led to baldness, patchy hair loss, and severe hair loss on his head. On June 8, 2024, he used the product invented by our company. The method of use was to apply it once a day, 15 ml each time. On June 15, hair roots began to appear. On June 28, hair grew in some areas, with a length of 1 cm.

[0016] (4) Mr. Yang, male, 72 years old, retired general manager of a company, with a bald spot on his forehead and head extending to the back of his head. He had been bald for 15 years. On June 16, 2024, he used the product of this invention. He applied it once a day, using 15 ml each time, and gently massaged his scalp for 3 minutes until absorbed. On June 27, hair roots began to appear on the top of his head and the back of his head, with a length of 1.2 cm. He continued to use it according to the course of treatment.

[0017] (5) Li Moumou, male, 42 years old, with hereditary baldness, used the product of this invention on June 2, 2024, applied it once a day, and used 15 ml each time. On June 18, hair roots began to appear, and on July 1, 2024, hair grew out with a length of 1 cm.

[0018] Example of a person with thinning hair. (6) Zhang Moumou, male, resident of Qingyuan Town, Yizhou District, 45 years old, with unexplained hair loss and thinning, and incomplete baldness. He started using the product of this invention on October 3, 2024, with the same usage and dosage as in example (4). On October 20, 2024, his family noticed that his hair was significantly thicker than before.

[0019] Example of preventing hair loss: (7) Mr. Feng, male, 49 years old, a staff member of a government agency in Yizhou District. Mr. Feng's hair was normal, without thinning or baldness. He used the product of this invention on August 22, 2024. Usage: Use this product as shampoo to wash his hair once a day, 10 to 15 ml each time. After two months of continuous use, on October 25, 2024, it was observed that his hair was thicker and denser than that of his peers, and even denser than that of his brother who did not use this product. It can be seen that the product of this invention has the effect of preventing hair loss. In the trial phase, 1,000 users have been tested and observed, and all have achieved good results. They are not listed here.

[0020] The above embodiments are merely examples to illustrate the effects of the present invention and are not within the scope of protection of the present invention. Any product made by simply changing the percentage of each component of the preparation of the present invention without creative thinking is still within the scope of protection of the present invention.

Claims

1. A silk protein composition for hair growth, comprising the following auxiliary preparations and percentages: 1% moisturizer, 1% fragrance agent, 1% cationic surfactant, 1% co-emulsifier, 1% preservative, 1% antioxidant, 0.5% oily component, 0.5% acidity regulator, and 5% trace components, wherein the trace components include Sapindus mukorossi fruit extract, lauryl glucoside, Citrus reticulata peel extract, sodium PCA, sodium lactate, arginine, aspartic acid, pyrrolidone carboxylic acid, glycine, alanine, serine, valine, proline, threonine, isoleucine, histidine, phenylalanine, sodium hyaluronate crosspolymer, sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed sodium hyaluronate, glycerin, butylene glycol, 1,2-hexanediol, ethylhexylglycerin, 1,2-pentanediol, and potassium sorbate, characterized in that... It also includes the following substances and percentages: water 70%, sodium lauroyl sarcosinate 3%, TEA cocoyl glutamate 2%, sodium lauroyl amphoteric acid 2%, sodium chloride 1%, phenoxyethanol 1%, sodium laurylate 0.5%, citric acid 0.5%, allantoin 0.5%, cocamidopropyl betaine 2%, methylparaben 0.5%, silk protein solution 2%, and nicotinamide 3%.

2. The silk protein composition for hair growth as described in claim 1, characterized in that... The moisturizer is at least one of glycerin, propylene glycol, butylene glycol, panthenol, sorbitol, dipropylene glycol, hexanediol, isopropanol, xylitol, trimethylglycine, and polyethylene glycol.

3. The silk protein composition for hair growth as described in claim 1, characterized in that, The fragrance agent is a flavoring, and the antioxidant is at least one of Polygonum cuspidatum, tea, and rosemary.

4. The silk protein composition for hair growth as described in claim 1, characterized in that, The cationic surfactant is lauryltrimethylammonium chloride.

5. The silk protein composition for hair growth as described in claim 1, characterized in that, The oily component is at least one of vegetable oil, triglycerides, branched-chain fatty alcohols, branched-chain fatty acids, and dimethyl silicone oil, and the vegetable oil is preferably ethoxylated vegetable oil.

6. The silk protein composition for hair growth as described in claim 1, characterized in that, The acidity regulator is citric acid or lactic acid.

7. The silk protein composition for hair growth as described in claim 1, characterized in that, The co-emulsifier is at least one of fatty alcohol, wax, and stearate, and the fatty alcohol is preferably 16-18 alcohol.

8. The silk protein composition for hair growth as described in claim 1, characterized in that, The preservative is at least one of parabens, Kathon, ethylhexylglycerin, phenoxyethanol, IPBC, sodium benzoate, and benzyl alcohol.