Sample analyzer

Abstract

The present invention is applicable to the field of in vitro diagnostic equipment, and discloses a sample analyzer, the sample analyzer comprises a sample determination assembly, a display and a controller, the controller is configured to: in response to a first trigger instruction, control the display to display a first calibration result interface; the first calibration result interface at least displays an abscissa axis, a first ordinate axis, a second ordinate axis and a first calibration curve of the first item, the first calibration curve comprises a first section of calibration curve and a second section of calibration curve which are connected to form a continuous curve, and the first ordinate axis is used for indicating the ordinate of the first section of calibration curve; the second ordinate axis is used for indicating the ordinate of the second section of calibration curve, and the first ordinate axis and the second ordinate axis have at least one of the following differences: the scale value range and the meaning indicated by the scale value. According to the method, a calibration result interface is simplified, and an operator can quickly and visually check all calibration curves of the same detection item on the same interface.

Description

Technical Field

[0001] This invention relates to the field of in vitro diagnostic equipment, and more particularly to a sample analyzer. Background Technology

[0002] Traditional sample analyzers typically use a single detection parameter (such as a single optical sensor and a single fixed detection wavelength) to measure each item. However, because the range of target analyte concentrations that can be measured using a single detection parameter is limited, the accuracy of the sample test results decreases when the target analyte concentration exceeds the range that can be measured using that single detection parameter.

[0003] To address the problems of traditional technologies, related technologies propose a scheme for measuring samples with different concentration ranges using different detection parameters (such as different photometric components and different wavelengths) within a single sample analyzer. This scheme requires using different detection parameters to perform calibration measurements on the calibrator during project calibration, resulting in different calibration curves. However, in practical applications, this technology still has the following shortcomings: different calibration curves for the same test item obtained using different detection parameters are displayed separately, leading to a cluttered display of calibration results for the same test item. This hinders operators from quickly and intuitively viewing all calibration curves for the same test item and from quickly and intuitively identifying key calibration information for the test item. Summary of the Invention

[0004] The first objective of this invention is to provide a sample analyzer that addresses the technical problem in related art where displaying different calibration curves for the same detection item separately is inconvenient for viewing.

[0005] To achieve the above objectives, the present invention provides a sample analyzer, comprising:

[0006] A sample measurement assembly, the sample measurement assembly being used to perform a calibration procedure for a first item on a calibrator containing a target analyte and the concentration of the target analyte being known; and to perform a sample measurement procedure for a sample used to detect the target analyte;

[0007] A display, the display being used at least to display a first calibration result interface for the first item;

[0008] A controller configured to: in response to a first trigger command, control the display to show the first calibration result interface;

[0009] The first calibration result interface displays at least a horizontal axis, a first vertical axis, a second vertical axis, and a first calibration curve for the first item. The first calibration curve includes a first calibration curve segment and a second calibration curve segment, which are connected to form a continuous curve. The horizontal axis indicates the horizontal coordinate of the first calibration curve segment and the horizontal coordinate of the second calibration curve segment. The horizontal coordinate values ​​of all points on the first calibration curve segment, except for the connection point connecting to the second calibration curve segment, are either less than or greater than the horizontal coordinate values ​​of all points on the second calibration curve segment. The first vertical axis indicates the vertical coordinate of the first calibration curve segment, and the second vertical axis indicates the vertical coordinate of the second calibration curve segment. The first vertical axis and the second vertical axis are spaced apart along the horizontal axis, and the first vertical axis and the second vertical axis differ in at least one of the following: the range of scale values ​​and the meaning of the scale values.

[0010] Alternatively, the first calibration result interface may display at least the first calibration curve of the first item. The first calibration curve includes a first segment calibration curve generated based on the first photometric result and a second segment calibration curve generated based on the second photometric result. The first photometric result and the second photometric result are obtained by the sample measurement component performing the calibration process of the first item on the calibrator using different detection parameters. The first segment calibration curve and the second segment calibration curve are connected to form a continuous curve, and the first segment calibration curve and the second segment calibration curve have different display information in at least one of the following: color, line type, line width, and identifier.

[0011] In one implementation, the first calibration result interface displays at least the horizontal axis, the first vertical axis, the second vertical axis, and the first calibration curve of the first item, and the first calibration curve and the second calibration curve have different display information in at least one of the following: color, line type, line width, and identifier.

[0012] In one implementation, the color, line type, and line width of the first calibration curve are consistent with the color, line type, and line width of the first vertical axis, respectively; and the color, line type, and line width of the second calibration curve are consistent with the color, line type, and line width of the second vertical axis, respectively.

[0013] And / or, the first calibration curve segment and the first vertical axis both have the same first identifier, and the second calibration curve segment and the second vertical axis both have the same second identifier.

[0014] In one implementation, the first calibration result interface displays at least the horizontal axis, the first vertical axis, the second vertical axis, and the first calibration curve of the first item, and the first calibration curve and the second calibration curve are located between the first vertical axis and the second vertical axis in a direction parallel to the horizontal axis.

[0015] And / or, the first calibration result interface displays at least the horizontal axis, the first vertical axis, the second vertical axis, and the first calibration curve of the first item, wherein the horizontal axis is used to indicate the scale value used to characterize the concentration, the first vertical axis is used to indicate the scale value used to characterize the reactivity or absorbance or luminescence value, and the second vertical axis is used to indicate the scale value used to characterize the reactivity or absorbance or luminescence value.

[0016] In one implementation, the first calibration result interface displays at least the horizontal axis, the first vertical axis, the second vertical axis, and the first calibration curve of the first item. The horizontal coordinate values ​​of all points on the first calibration curve, except for the connection points connected to the second calibration curve, are smaller than the horizontal coordinate values ​​of all points on the second calibration curve. The scale value range of the first vertical axis is larger than the scale value range of the second vertical axis.

[0017] And / or, the connection between the first calibration curve segment and the second calibration curve segment is a smooth transition.

[0018] In one implementation, the controller is also configured to perform the following calibration procedure for the first item:

[0019] The sample measurement component is controlled to perform the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, thereby obtaining multiple first photometric results that correspond one-to-one with the multiple first calibrators;

[0020] The sample measurement component is controlled to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, thereby obtaining multiple second photometric results that correspond one-to-one with the at least two second calibrators;

[0021] The first calibration curve is generated based on the concentration of the target analyte in the plurality of first calibrators, the plurality of first photometric results, the concentration of the target analyte in the plurality of second calibrators, and the plurality of second photometric results;

[0022] Wherein, at least one of the plurality of second calibrators contains a concentration of the target analyte greater than the concentration of the target analyte in the plurality of first calibrators, and at least another of the plurality of second calibrators contains a concentration of the target analyte less than or equal to the concentration of the target analyte in at least one of the first calibrators;

[0023] The first optical measurement result and the second optical measurement result are obtained by the sample measurement component performing the first sub-calibration process of the first item on the first calibrator and the second sub-calibration process of the first item on the second calibrator using different detection parameters.

[0024] As one implementation, generating the first calibration curve based on the concentration of the target analyte in the plurality of first calibrators, the plurality of first photometric results, the concentration of the target analyte in the plurality of second calibrators, and the plurality of second photometric results includes:

[0025] The first calibration curve is generated based on the concentration of the target analyte in the plurality of first calibrators and the plurality of first photometric results.

[0026] The second calibration curve is generated based on the concentration of the target analyte in the plurality of second calibrators and the plurality of second photometric results.

[0027] The second calibration curve is shifted so that it is joined with the first calibration curve to form a continuous curve, thus obtaining the first calibration curve.

[0028] In one implementation, after the second calibration curve segment is translated to form a continuous curve by splicing the second calibration curve segment with the first calibration curve segment, the controller is further configured to scale the second calibration curve segment and the second ordinate to make the connection between the first calibration curve segment and the second calibration curve segment smooth.

[0029] In one embodiment, the sample measurement assembly includes a sample dispensing component, a reagent dispensing component, and an optical measurement component. The sample dispensing component is used to add the first calibrator and the second calibrator into different reaction containers, respectively. The reagent dispensing component is used to add reagents into the different reaction containers. The optical measurement component is used to perform optical measurement on the reaction solution in the reaction container, which is made of at least one of the first calibrator and the second calibrator and the reagent.

[0030] The different detection parameters include any of the following: different components and / or different concentrations of reagents, different photometric components, different wavelengths of light, different reaction times, and different blank times.

[0031] In one implementation, when the different detection parameters include reagents with different components and / or different concentrations, the control of the sample measurement component to perform a first sub-calibration process of the first item on multiple first calibrators containing the target analyte and with different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively:

[0032] The reagent dispensing component is controlled to add the first reagent into the first reaction vessel;

[0033] The sample dispensing component is controlled to add the first calibrator into the first reaction vessel;

[0034] The optical measurement component is controlled to perform optical measurement on the first reaction liquid in the first reaction container, which is made of at least the first calibrator and the first reagent, to obtain the first optical measurement result;

[0035] The control of the sample measurement component performs a second sub-calibration process of the first item on multiple second calibrators containing the target analyte and with different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively:

[0036] The reagent dispensing component is controlled to add the first reagent into the second reaction vessel;

[0037] The sample dispensing component is controlled to add the second calibrator into the second reaction vessel;

[0038] The reagent dispensing component is controlled to add the second reagent into the second reaction vessel;

[0039] The optical measurement component is controlled to perform optical measurement on the second reaction liquid in the second reaction vessel, which is made of at least the second calibrator, the first reagent and the second reagent, to obtain the second optical measurement result;

[0040] Wherein, the first reagent and the second reagent differ in at least one of the following: components and concentrations;

[0041] Alternatively, when the different detection parameters include different photometric components, the sample measurement assembly includes a first photometric component and a second photometric component. The control of the sample measurement assembly to perform a first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results that correspond one-to-one with the multiple first calibrators, includes performing the following process on the multiple first calibrators respectively: controlling the first photometric component to perform optical measurement on a first reaction liquid in a first reaction vessel made of at least the first calibrator and reagents, to obtain the first photometric result;

[0042] The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the second photometric component to perform optical measurement on the second reaction liquid in the second reaction vessel, which is at least made of the second calibrator and reagents, to obtain the second photometric result;

[0043] Among them, one of the first optical measurement component and the second optical measurement component is a transmission light detector, and the other is a scattering light detector;

[0044] Alternatively, when the different detection parameters include reagents with different components and / or different concentrations and different photometric components, the sample measurement assembly includes a first photometric component and a second photometric component;

[0045] The control of the sample measurement component to perform a first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the reagent dispensing component to add a first reagent into a first reaction container; controlling the sample dispensing component to add the first calibrator into the first reaction container; controlling the first photometric component to perform optical measurement on a first reaction solution in the first reaction container made of at least the first calibrator and the first reagent, to obtain the first photometric result;

[0046] The control of the sample measurement component to perform a second sub-calibration process of the first item on multiple second calibrators containing the target analyte and with different concentrations of the target analyte, to obtain multiple second photometric results corresponding one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the reagent dispensing component to add a first reagent into a second reaction container; controlling the sample dispensing component to add a second calibrator into a second reaction container; controlling the reagent dispensing component to add a second reagent into a second reaction container; controlling the second photometric component to perform optical measurement on a second reaction solution in the second reaction container made of at least the second calibrator, the first reagent, and the second reagent, to obtain the second photometric result;

[0047] Wherein, the first reagent and the second reagent differ in at least one of the following: components and concentrations;

[0048] One of the first optical measurement component and the second optical measurement component is a transmitted light detector, and the other is a scattered light detector;

[0049] Alternatively, when the different detection parameters include light of different wavelengths, the control of the sample measurement component performs the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the photometric component to perform optical measurement of light of the first wavelength on the first reaction liquid in the first reaction container, which is made of at least the first calibrator and the reagent, to obtain the first photometric result;

[0050] The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the photometric component to perform optical measurement of a second wavelength of light on a second reaction liquid in a second reaction vessel made of at least the second calibrator and reagents, to obtain the second photometric result;

[0051] Wherein, the wavelength of the second wavelength light is greater than or less than the wavelength of the first wavelength light;

[0052] Alternatively, when the different detection parameters include different reaction times, the control of the sample measurement component performs the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results that correspond one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the photometric component to perform optical measurement on the first reaction liquid in the first reaction container, which is at least made of the first calibrator and reagent under the first reaction time, to obtain the first photometric result;

[0053] The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the photometric component to perform optical measurement on the second reaction liquid in the second reaction vessel, which is at least made of the second calibrator and reagent under the second reaction time, to obtain the second photometric result;

[0054] Wherein, the second reaction time is greater than or less than the first reaction time;

[0055] Alternatively, when the different detection parameters include different blank durations, the control of the sample measurement component to perform the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the photometric component to perform optical measurement on the first reaction liquid in the first reaction vessel prepared by at least the first calibrator and reagent under the first blank duration, to obtain the first photometric result;

[0056] The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the photometric component to perform optical measurement on the second reaction liquid prepared in the second reaction vessel by at least the second calibrator and reagent under the second blank time, to obtain the second photometric result;

[0057] Wherein, the second blank duration is greater than or less than the first blank duration.

[0058] As one implementation, generating the first calibration curve based on the concentration of the target analyte in the plurality of first calibrators, the plurality of first photometric results, the concentration of the target analyte in the plurality of second calibrators, and the plurality of second photometric results includes: generating a second calibration curve based on the concentration of the target analyte in the plurality of first calibrators and the plurality of first photometric results, wherein the second calibration curve includes a first calibration curve segment and a third calibration curve segment connected to each other, and the abscissa values ​​of all points on the third calibration curve segment, except for the connection points connecting to the first calibration curve segment, are greater than the abscissa values ​​of all points on the first calibration curve segment; based on the concentration of the target analyte in the plurality of first calibrators, the plurality of first photometric results, the first calibration curve segment, the second calibration curve segment, the third ... The concentration of the target analyte in the two calibrators and the multiple second photometric results are used to generate a third calibration curve. The third calibration curve includes two interconnected calibration curve segments: the second and fourth. The x-coordinate values ​​of all points on the fourth calibration curve, except for the connection point with the second calibration curve segment, are smaller than the x-coordinate values ​​of all points on the second calibration curve segment. The third calibration curve is then shifted so that the connection point between the second and fourth calibration curve segments coincides with the connection point between the first and third calibration curve segments. Finally, the third and fourth calibration curve segments are deleted to obtain the first calibration curve.

[0059] And / or, in one of the plurality of first calibrators, the concentration of the target analyte in the first calibrator is equal to zero, and in one of the plurality of second calibrators, the concentration of the target analyte in the second calibrator is equal to zero.

[0060] In one implementation, the display is further configured to display a second calibration result interface for the first item, wherein the second calibration result interface displays at least the first calibration curve segment and the second calibration curve segment that are spaced apart from and / or independently set; the controller is further configured to: in response to a second trigger command, control the display to switch from displaying the first calibration result interface to displaying the second calibration result interface; and in response to a third trigger command, control the display to switch from displaying the second calibration result interface to displaying the first calibration result interface; wherein the second trigger command includes: an instruction formed by an operator performing an interface switching operation on the first calibration result interface through at least one of screen touch, mouse operation, keyboard operation, and voice input; and the third trigger command includes: an instruction formed by an operator performing an interface switching operation on the second calibration result interface through at least one of screen touch, mouse operation, keyboard operation, and voice input.

[0061] And / or, the display is also used to display a project calibration management interface, which at least displays calibration management information for the first project; the first trigger instruction includes: an instruction formed by an operator viewing the first project in the project calibration management interface through at least one of screen touch, mouse operation, keyboard operation, and voice input.

[0062] In one implementation, the first calibration result interface displays at least the horizontal axis, the first vertical axis, the second vertical axis, and the first calibration curve of the first item, and the first calibration result interface also displays a third vertical axis. The first calibration curve also includes a fifth calibration curve, and the first calibration curve, the second calibration curve, and the fifth calibration curve are connected sequentially to form a continuous curve.

[0063] The horizontal axis is also used to indicate the horizontal coordinate of the fifth calibration curve. The horizontal coordinate values ​​of all points on the fifth calibration curve, except for the connection point connected to the second calibration curve, are different from the horizontal coordinate values ​​of the points on the second calibration curve and the horizontal coordinate values ​​of the points on the first calibration curve.

[0064] The third vertical axis is used to indicate the vertical coordinate of the fifth calibration curve. Any two of the first, second, and third vertical axes are spaced apart along the horizontal axis, and any two of the first, second, and third vertical axes have at least one difference in the following aspects: the range of scale values ​​and the meaning of the scale values.

[0065] Preferably, the display information of the fifth calibration curve is different from the display information of the first calibration curve and the display information of the second calibration curve in at least one of the following: color, line type, line width, and identifier.

[0066] In one implementation, the controller is configured to control the sample measurement component to perform the sample measurement procedure of the first item on the sample to obtain a third optical measurement result and a fourth optical measurement result;

[0067] Based on the third photometric result and the first calibration curve, the first measurement data is obtained;

[0068] Based on the fourth photometric result and the second calibration curve, the second measurement data is obtained;

[0069] Based on the first measurement data and the second measurement data, the test results of the sample regarding the first item are obtained.

[0070] A second objective of the present invention is to provide a sample analyzer comprising:

[0071] A sample measurement assembly, the sample measurement assembly being used to perform a calibration procedure for a first item on a calibrator containing a target analyte and the concentration of the target analyte being known; and to perform a sample measurement procedure for a sample used to detect the target analyte;

[0072] The controller is configured to perform the following calibration procedure for the first item:

[0073] The sample measurement component is controlled to perform the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, thereby obtaining multiple first photometric results that correspond one-to-one with the multiple first calibrators;

[0074] The sample measurement component is controlled to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, thereby obtaining multiple second photometric results that correspond one-to-one with the at least two second calibrators;

[0075] Based on the concentration of the target analyte in the plurality of first calibrators, the plurality of first photometric results, the concentration of the target analyte in the plurality of second calibrators, and the plurality of second photometric results, a continuous first calibration curve is output;

[0076] Wherein, at least one of the plurality of second calibrators contains a concentration of the target analyte greater than the concentration of the target analyte in the plurality of first calibrators, and at least another of the plurality of second calibrators contains a concentration of the target analyte less than or equal to the concentration of the target analyte in at least one of the first calibrators;

[0077] The sample measurement assembly includes a sample dispensing component, a reagent dispensing component, and an optical measurement component. The sample dispensing component is used to add the first calibrator and the second calibrator into different reaction containers, respectively. The reagent dispensing component is used to add reagents into the different reaction containers. The optical measurement component is used to perform optical measurement on the reaction solution in the reaction container, which is made of at least one of the first calibrator and the second calibrator and the reagent.

[0078] The first optical measurement result and the second optical measurement result are obtained by the sample measurement component performing the first sub-calibration process of the first item on the first calibrator and the second sub-calibration process of the first item on the second calibrator using different detection parameters.

[0079] As one implementation, generating a continuous first calibration curve based on the concentration of the target analyte in the plurality of first calibrators, the plurality of first photometric results, the concentration of the target analyte in the plurality of second calibrators, and the plurality of second photometric results includes:

[0080] A first calibration curve is generated based on the concentration of the target analyte in the plurality of first calibrators and the plurality of first photometric results;

[0081] A second calibration curve is generated based on the concentration of the target analyte in the plurality of second calibrators and the plurality of second photometric results;

[0082] The second calibration curve is shifted so that it is joined with the first calibration curve to form a continuous curve, thus obtaining the first calibration curve.

[0083] As one implementation method, the different detection parameters include any of the following: different components and / or different concentrations of reagents, different photometric components, different wavelengths of light, different reaction times, and different blank times.

[0084] In one implementation, when the different detection parameters include reagents with different components and / or different concentrations, the control of the sample measurement component to perform a first sub-calibration process of the first item on multiple first calibrators containing the target analyte and with different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively:

[0085] The reagent dispensing component is controlled to add the first reagent into the first reaction vessel;

[0086] The sample dispensing component is controlled to add the first calibrator into the first reaction vessel;

[0087] The optical measurement component is controlled to perform optical measurement on the first reaction liquid in the first reaction container, which is made of at least the first calibrator and the first reagent, to obtain the first optical measurement result;

[0088] The control of the sample measurement component performs a second sub-calibration process of the first item on multiple second calibrators containing the target analyte and with different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively:

[0089] The reagent dispensing component is controlled to add the first reagent into the second reaction vessel;

[0090] The sample dispensing component is controlled to add the second calibrator into the second reaction vessel;

[0091] The reagent dispensing component is controlled to add the second reagent into the second reaction vessel;

[0092] The optical measurement component is controlled to perform optical measurement on the second reaction liquid in the second reaction vessel, which is made of at least the second calibrator, the first reagent and the second reagent, to obtain the second optical measurement result;

[0093] Wherein, the first reagent and the second reagent differ in at least one of the following: components and concentrations;

[0094] Alternatively, when the different detection parameters include different photometric components, the sample measurement assembly includes a first photometric component and a second photometric component. The control of the sample measurement assembly to perform a first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results that correspond one-to-one with the multiple first calibrators, includes performing the following process on the multiple first calibrators respectively: controlling the first photometric component to perform optical measurement on a first reaction liquid in a first reaction vessel made of at least the first calibrator and reagents, to obtain the first photometric result;

[0095] The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the second photometric component to perform optical measurement on the second reaction liquid in the second reaction vessel, which is at least made of the second calibrator and reagents, to obtain the second photometric result;

[0096] Among them, one of the first optical measurement component and the second optical measurement component is a transmission light detector, and the other is a scattering light detector;

[0097] Alternatively, when the different detection parameters include reagents with different components and / or different concentrations and different photometric components, the sample measurement assembly includes a first photometric component and a second photometric component. Controlling the sample measurement assembly to perform a first sub-calibration process of the first item on multiple first calibrators containing the target analyte and with different concentrations of the target analyte, yielding multiple first photometric results corresponding one-to-one with the multiple first calibrators, includes performing the following process on each of the multiple first calibrators:

[0098] The reagent dispensing component is controlled to add the first reagent into the first reaction vessel;

[0099] The sample dispensing component is controlled to add the first calibrator into the first reaction vessel;

[0100] The first optical measurement component is controlled to perform optical measurement on the first reaction liquid in the first reaction container, which is made of at least the first calibrator and the first reagent, to obtain the first optical measurement result;

[0101] The control of the sample measurement component performs a second sub-calibration process of the first item on multiple second calibrators containing the target analyte and with different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively:

[0102] The reagent dispensing component is controlled to add the first reagent into the second reaction vessel;

[0103] The sample dispensing component is controlled to add the second calibrator into the second reaction vessel;

[0104] The reagent dispensing component is controlled to add the second reagent into the second reaction vessel;

[0105] The second photometric component is controlled to perform optical measurements on the second reaction liquid in the second reaction vessel, which is made of at least the second calibrator, the first reagent and the second reagent, to obtain the second photometric result.

[0106] Wherein, the first reagent and the second reagent differ in at least one of the following: components and concentrations;

[0107] One of the first optical measurement component and the second optical measurement component is a transmitted light detector, and the other is a scattered light detector;

[0108] Alternatively, when the different detection parameters include light of different wavelengths, the control of the sample measurement component performs the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the photometric component to perform optical measurement of light of the first wavelength on the first reaction liquid in the first reaction container, which is made of at least the first calibrator and the reagent, to obtain the first photometric result;

[0109] The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the photometric component to perform optical measurement of a second wavelength of light on a second reaction liquid in a second reaction vessel made of at least the second calibrator and reagents, to obtain the second photometric result;

[0110] Wherein, the wavelength of the second wavelength light is greater than or less than the wavelength of the first wavelength light;

[0111] Alternatively, when the different detection parameters include different reaction times, the control of the sample measurement component performs the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results that correspond one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the photometric component to perform optical measurement on the first reaction liquid in the first reaction container, which is at least made of the first calibrator and reagent under the first reaction time, to obtain the first photometric result;

[0112] The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the photometric component to perform optical measurement on the second reaction liquid in the second reaction vessel, which is at least made of the second calibrator and reagent under the second reaction time, to obtain the second photometric result;

[0113] Wherein, the second reaction time is greater than or less than the first reaction time;

[0114] Alternatively, when the different detection parameters include different blank durations, the control of the sample measurement component to perform the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the photometric component to perform optical measurement on the first reaction liquid in the first reaction vessel prepared by at least the first calibrator and reagent under the first blank duration, to obtain the first photometric result;

[0115] The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the photometric component to perform optical measurement on the second reaction liquid prepared in the second reaction vessel by at least the second calibrator and reagent under the second blank time, to obtain the second photometric result;

[0116] Wherein, the second blank duration is greater than or less than the first blank duration.

[0117] The sample analyzer provided by this invention optimizes the first calibration result interface for a first item, displaying a continuous first calibration curve formed by connecting different calibration curve segments. This effectively simplifies the calibration result interface by processing different calibration curves for the same test item into a single continuous curve, allowing operators to quickly and intuitively view all calibration curves for the same test item on a single interface. Furthermore, this invention displays different calibration curve segments using different vertical axes and / or different display information on the same interface, facilitating operators to intuitively and quickly obtain the corresponding information for different calibration curve segments, thereby enabling them to quickly and intuitively acquire key calibration information for the test item. Attached Figure Description

[0118] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.

[0119] Figure 1 This is a schematic diagram of the first calibration curve provided in an embodiment of the present invention;

[0120] Figure 2 This is a schematic diagram of the second and third calibration curves provided in an embodiment of the present invention;

[0121] Figure 3 This is a schematic diagram of the sample analyzer provided in an embodiment of the present invention.

[0122] The diagram numbers are as follows: 100, sample dispensing component; 200, reagent dispensing component; 300, photometric component; 400, controller; 500, reaction carrier component; 600, reagent storage component; 700, sample injection component; L1, first calibration curve; L2, second calibration curve; L3, third calibration curve; L4, fourth calibration curve; X, horizontal axis; Y1, first vertical axis; Y2, second vertical axis. Detailed Implementation

[0123] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0124] The sample analyzer provided in this embodiment of the invention is suitable for expanding the measurable concentration range of a target analyte by using at least one of the following methods: different components and / or reagents of different concentrations, different photometric components, different wavelengths of light, different reaction times, and different blank times.

[0125] The sample analyzer provided in the first aspect of this invention includes a sample measurement component, which performs a sample measurement procedure on a sample to measure a target analyte in the sample. The sample is collected from a human or animal.

[0126] In one implementation, the sample measurement component is also used to perform a calibration procedure on a calibrator containing a target analyte at a known concentration. In addition to measuring samples, the sample analyzer of this embodiment requires periodic calibration using calibrators. The data obtained from the sample measurement is then calibrated based on the calibrated data to obtain the sample detection results, thereby ensuring the accuracy of the sample detection results.

[0127] Reference Figure 3 As shown, in one embodiment, the sample analyzer also includes a display and a controller 400. The display is used to show at least the calibration result interface. The controller 400 is configured to control the display to show the calibration result interface in response to a trigger command. The calibration result interface can display calibration data obtained according to the project calibration process. In this embodiment, displaying the calibration result interface on the display facilitates operators to quickly and intuitively view the relevant data of the project calibration.

[0128] In one implementation, the sample measurement component is used to perform a calibration procedure for a first item on a calibrator containing a target analyte and whose concentration is known; and to perform a sample measurement procedure for a sample used to detect the target analyte. The display is used to show at least a first calibration result interface for the first item. The controller 400 is configured to control the display to show the first calibration result interface in response to a first trigger command. The sample analyzer can perform calibration procedures and sample measurement procedures for multiple items. Each item's calibration procedure is performed, corresponding to calibration data for that item, which is displayed on the calibration result interface for that item. Furthermore, the calibration data for that item can be used to calibrate the sample measurement data for that item.

[0129] Reference Figure 1 As shown, in one embodiment, the first calibration result interface displays at least the horizontal axis X, the first vertical axis Y1, the second vertical axis Y2, and the first calibration curve of the first item. The first calibration curve includes a first calibration curve L1 and a second calibration curve L2, which are connected to form a continuous curve. The horizontal axis X is used to indicate the horizontal coordinate of the first calibration curve L1 and the horizontal coordinate of the second calibration curve L2. The horizontal coordinate values ​​of all points on the first calibration curve L1, except for the connection point with the second calibration curve L2, are all less than or greater than the horizontal coordinate values ​​of all points on the second calibration curve L2. The first vertical axis Y1 is used to indicate the vertical coordinate of the first calibration curve L1, and the second vertical axis Y2 is used to indicate the vertical coordinate of the second calibration curve L2. The first vertical axis Y1 and the second vertical axis Y2 are spaced apart along the horizontal axis X, and the first vertical axis Y1 and the second vertical axis Y2 differ in at least one of the following: the range of scale values ​​and the meaning of the scale values. The first calibration curve L1 and the second calibration curve L2 are displayed on the same interface, sharing a common horizontal axis but not a common vertical axis, within the same coordinate system. This implementation scheme optimizes the first calibration result interface for the first item, displaying a continuous first calibration curve formed by connecting different calibration curve segments. This effectively simplifies the calibration result interface by processing different calibration curves for the same test item into a single continuous curve, allowing operators to quickly and intuitively view all calibration curves for the same test item on a single interface. Furthermore, this implementation scheme displays different calibration curve segments using different vertical axes on the same interface, facilitating operators to intuitively and quickly obtain the corresponding information for different calibration curve segments, thereby enabling them to quickly and intuitively acquire key calibration information for the test item.

[0130] In one implementation, the scale values ​​of the first vertical axis Y1 and the second vertical axis Y2 are different, including at least one of the following situations: the difference between the maximum and minimum scale values ​​displayed on the first vertical axis Y1 is different from the difference between the maximum and minimum scale values ​​displayed on the second vertical axis Y2; the values ​​indicated by the scale on the first vertical axis Y1 are different from the values ​​indicated by the scale on the second vertical axis Y2; the difference between two adjacent scales on the first vertical axis Y1 is different from the difference between two adjacent scales on the second vertical axis Y2.

[0131] In one implementation, the scale values ​​of the first vertical axis Y1 and the second vertical axis Y2 have different meanings, including at least one of the following situations: one of the first vertical axis Y1 and the second vertical axis Y2 is used to characterize the scattered light measurement value, and the other is used to characterize the transmitted light measurement value; one of the first vertical axis Y1 and the second vertical axis Y2 is used to characterize the absorbance, and the other is used to characterize the luminescence value; one of the first vertical axis Y1 and the second vertical axis Y2 is used to characterize the reactivity, and the other is used to characterize the absorbance or luminescence value.

[0132] In one implementation, the first calibration curve L1 is generated based on the first photometric result, and the second calibration curve L2 is generated based on the second photometric result. That is, the first calibration curve includes the first calibration curve L1 generated from the first photometric result and the second calibration curve L2 generated from the second photometric result. The first and second photometric results are obtained by the sample measurement component performing the first calibration procedure on the calibrator using different detection parameters. By using different detection parameters, the sample analyzer can broaden the measurable range of the target analyte. For example, one detection parameter may have high accuracy for low concentration range measurements, while another may have high accuracy for high concentration range measurements, thus enabling the sample analyzer to meet a wider range of accurate measurement requirements. The first calibration curve L1 and the second calibration curve L2 are obtained by the sample measurement component performing the first calibration procedure on the calibrator using different detection parameters. In this implementation scheme, the first calibration curve L1 and the second calibration curve L2 obtained by calibration with different detection parameters are displayed in the same coordinate system by sharing a horizontal axis but not sharing a vertical axis, and are connected to form a continuous curve. This is equivalent to connecting different calibration curves obtained by calibrating the same test item with different detection parameters to form a continuous curve and displaying it in the same coordinate system. This makes the calibration result interface of the item relatively simple, and allows operators to quickly and intuitively view all calibration curves obtained by calibrating the same test item with different detection parameters on the same interface. This helps operators to quickly and intuitively obtain the key calibration information of the test item.

[0133] As one implementation method, different detection parameters include any of the following: different components and / or different concentrations of reagents, different photometric components 300, different wavelengths of light, different reaction times, and different blank times. The sample measurement assembly includes a photometric component 300. Reagents are used to react with samples or calibrators to prepare a reaction solution. The reaction time refers to the reaction time between the reagent and the sample, or the reaction time between the reagent and the calibrator, or the interval between the blank test point and the final test point of the sample. The blank time refers to the interval between the blank test point and the start of the measurement cycle. The photometric component 300 is used to measure the reaction solution using a preset wavelength of light. According to the applicant's research, samples or calibrators with different target concentrations can be accurately measured by reacting with reagents of different components and / or different concentrations, by using different photometric components 300, by measuring different wavelengths of light, by setting different reaction times, and by setting different blank times.

[0134] In one implementation, the first calibration curve L1 and the second calibration curve L2 differ in at least one of the following display information: color, line type, line width, and identifier. Line types include, but are not limited to, solid lines, dashed lines, and dotted lines. Different line widths specifically refer to the different thicknesses of the first calibration curve L1 and the second calibration curve L2. Identifiers include, but are not limited to, text identifiers, symbol identifiers, and pattern identifiers. Different identifiers can, for example, be used to characterize different detection parameters. In this implementation, the first calibration curve L1 and the second calibration curve L2 are obtained using different detection parameters for the same project, and are distinguished and displayed in the same coordinate system using different display methods, making it easier for operators to intuitively and quickly distinguish between the first calibration curve L1 and the second calibration curve L2. This implementation displays different segments of the calibration curve with different display information on the same interface, which helps operators intuitively and quickly obtain the corresponding information of different segments of the calibration curve, thereby facilitating operators to quickly and intuitively obtain the key calibration information of the detection project.

[0135] In one implementation, the first calibration result interface displays at least the horizontal axis X, the first vertical axis Y1, the second vertical axis Y2, and the first calibration curve of the first item. The first calibration curve L1 and the second calibration curve L2 differ in at least one of the following display information: color, line type, line width, and identifier. This implementation displays different segments of the calibration curve using different vertical axes and different display information on the same interface, making it easier for operators to intuitively and quickly distinguish the first calibration curve L1 and the second calibration curve L2, as well as the first and second vertical axes.

[0136] In one implementation, the display information of the first calibration curve L1 is consistent with the display information of the first vertical axis Y1, and the display information of the second calibration curve L2 is consistent with the display information of the second vertical axis Y2. This makes it easier for operators to view the first calibration curve L1 in relation to the first vertical axis Y1 and the second calibration curve L2 in relation to the second vertical axis Y2.

[0137] In one implementation, the color, line type, and line width of the first calibration curve L1 are consistent with the color, line type, and line width of the first vertical axis Y1, and the color, line type, and line width of the second calibration curve L2 are consistent with the color, line type, and line width of the second vertical axis Y2. This method achieves the effect of making the display information of the first calibration curve L1 consistent with the first vertical axis Y1, and the display information of the second calibration curve L2 consistent with the second vertical axis Y2.

[0138] In one implementation, when the first calibration curve L1, the first vertical axis Y1, the second calibration curve L2, and the second vertical axis Y2 all have labels, the first calibration curve L1 and the first vertical axis Y1 have the same first label, and the second calibration curve L2 and the second vertical axis Y2 have the same second label. That is, the first calibration curve L1 and the first vertical axis Y1 have the same label, and the second calibration curve L2 and the second vertical axis Y2 have the same label. The first label is different from the second label. The first label and the second label can be used to characterize different detection parameters, so that operators can better associate the first calibration curve L1 and the second calibration curve L2 with the corresponding detection parameters.

[0139] In one implementation, the first calibration curve L1 and the second calibration curve L2 are located between the first vertical axis Y1 and the second vertical axis Y2 in a direction parallel to the horizontal axis X. That is, the first vertical axis Y1 and the second vertical axis Y2 are located on the left and right sides of the horizontal axis X. This helps to avoid confusion between the first vertical axis Y1 and the second vertical axis Y2.

[0140] In one implementation, the second calibration curve L2 is located between the first calibration curve L1 and the second ordinate axis Y2 in a direction parallel to the x-axis. Specifically, the first calibration curve L1 is positioned closer to the first ordinate axis Y1, and the second calibration curve L2 is positioned closer to the second ordinate axis Y2. This allows operators to easily view the ordinate of the first calibration curve L1 against the first ordinate axis Y1 and the ordinate of the second calibration curve L2 against the second ordinate axis Y2.

[0141] In one implementation, the horizontal axis X is used to indicate the scale value used to characterize the concentration, with the unit being %. The first vertical axis Y1 is used to indicate the scale value used to characterize the reactivity, and the second vertical axis Y2 is used to indicate the scale value used to characterize the reactivity. The reactivity can be calculated using the endpoint method or the fixed-time method. When the reactivity is calculated using the endpoint method, the formula for calculating the reactivity is R = A. i -k*A b Where R is the reactivity and A i A represents the absorbance at the reaction time measurement point (i.e., the final test point of the sample above). b This refers to the absorbance at the blank time measurement point (i.e., the blank test point mentioned above); k is the volume correction factor, which varies depending on the parameters of different detection items. In this implementation scheme, the ordinates of different calibration curves measured with different parameters are converted into reactivity for display. This facilitates the processing of the first calibration curve L1 and the second calibration curve L2 into a continuous calibration curve, and allows operators to better compare and observe the differences between the first calibration curve L1 and the second calibration curve L2. Of course, in specific applications, as an alternative implementation scheme, the first ordinate axis Y1 can also be used to indicate the scale value used to characterize absorbance or luminescence, and the second ordinate axis Y2 can also be used to indicate the scale value used to characterize absorbance or luminescence.

[0142] In one implementation, the abscissa values ​​of all points on the first calibration curve L1, except for the connection point with the second calibration curve L2, are smaller than the abscissa values ​​of all points on the second calibration curve L2. The scale range of the first ordinate Y1 is larger than the scale range of the second ordinate Y2. The first calibration curve L1 is used to characterize low-value (low-concentration) calibration curves; that is, low-concentration samples calibrated using the first calibration curve L1 will have higher accuracy. The second calibration curve L2 is used to characterize high-value (high-concentration) calibration curves; that is, high-concentration samples calibrated using the second calibration curve L2 will have higher accuracy.

[0143] In one implementation, the connection between the first calibration curve L1 and the second calibration curve L2 is a smooth transition. In this embodiment, by processing the first calibration curve L1 and the second calibration curve L2, the connection between the first calibration curve L1 and the second calibration curve L2 can be made smooth, thereby making the connection between the first calibration curve L1 and the second calibration curve L2 more natural.

[0144] In one implementation, the controller 400 is further configured to perform the following calibration procedure for the first item: controlling the sample measurement component to perform a first sub-calibration procedure for the first item on multiple first calibrators containing target analytes with different concentrations of target analytes, obtaining multiple first photometric results corresponding one-to-one with the multiple first calibrators; controlling the sample measurement component to perform a second sub-calibration procedure for the first item on multiple second calibrators containing target analytes with different concentrations of target analytes, obtaining multiple second photometric results corresponding one-to-one with at least two second calibrators; and generating a first calibration curve based on the concentrations of target analytes in the multiple first calibrators, the multiple first photometric results, the concentrations of target analytes in the multiple second calibrators, and the multiple second photometric results. Wherein, at least one of the multiple second calibrators contains a target analyte concentration greater than the concentrations of target analytes in the multiple first calibrators, and at least another of the multiple second calibrators contains a target analyte concentration less than or equal to the concentration of target analytes in at least one first calibrator, i.e., the target analyte concentration ranges of the multiple first calibrators and the multiple second calibrators partially overlap. The first and second photometric results are obtained by the sample measurement component performing a first sub-calibration process for the first item on the first calibrator and a second sub-calibration process for the first item on the second calibrator using different detection parameters. In this embodiment, "multiple" refers to two or more. In this implementation, different detection parameters are used to calibrate the same item, and the target concentration ranges of the multiple first calibrators and the multiple second calibrators using different detection parameters partially overlap. That is, the abscissas of different segments of the calibration curves measured using different detection parameters have overlapping regions. This facilitates the processing of different segments of the calibration curves measured using different detection parameters into a continuous calibration curve.

[0145] In one implementation, generating a first calibration curve based on the concentrations of the target analyte in multiple first calibrators, multiple first photometric results, the concentrations of the target analyte in multiple second calibrators, and multiple second photometric results includes: generating a first calibration curve L1 based on the concentrations of the target analyte in multiple first calibrators and the multiple first photometric results; generating a second calibration curve L2 based on the concentrations of the target analyte in multiple second calibrators and the multiple second photometric results; and shifting the second calibration curve L2 so that it is joined with the first calibration curve L1 to form a continuous curve, thereby obtaining the first calibration curve. In this implementation, the first calibration curve L1 is obtained by calibrating multiple first calibrators using first detection parameters, and the second calibration curve L2 is obtained by calibrating multiple second calibrators using second detection parameters. Furthermore, the concentration ranges of the target analyte in the multiple first calibrators and the concentration ranges of the target analyte in the multiple second calibrators partially overlap, thereby facilitating the formation of a continuous calibration curve from the first calibration curve L1 and the second calibration curve L2.

[0146] In practical applications, the connection point is pre-identified in the overlapping region of the target concentration ranges of multiple first calibrators and multiple second calibrators. The target concentration range before the connection point is calibrated using the first calibration curve L1, and the target concentration range after the connection point is calibrated using the second calibration curve L2. This connection point can be preset in the sample analyzer. After obtaining the first and second calibration curves L1 and L2, the second calibration curve L2 is translated using the x-coordinate of the preset connection point as a reference, so that the first and second calibration curves L1 and L2 intersect at the connection point to obtain the first calibration curve. This implementation scheme uses the translation method to stitch the first and second calibration curves L1 and L2 into a continuous calibration curve, which is a simple process. Of course, in practical applications, other methods can also be used to process different calibration curves obtained from different detection parameters into a continuous calibration curve.

[0147] In one implementation, after translating the second calibration curve L2 to form a continuous curve by splicing it with the first calibration curve L1, the controller 400 is further configured to scale the second calibration curve L2 and the second ordinate Y2 to ensure a smooth transition at the junction of the first and second calibration curves L1 and L2. Since the curvatures of the first and second calibration curves L1 and L2 are different, the translated and spliced ​​calibration curves may have uneven transitions at the junctions. This implementation reduces the unevenness caused by the difference in curvature through scaling.

[0148] Reference Figure 3 As shown, in one embodiment, the sample measurement assembly includes a sample dispensing component 100, a reagent dispensing component 200, and an optical measurement component 300. The sample dispensing component 100 is used to add calibrators into the reaction container, the reagent dispensing component 200 is used to add reagents into the reaction container, and the optical measurement component 300 is used to perform optical measurements on the reaction solution in the reaction container, which is made from at least one of the calibrators and the reagents. Specifically, the sample dispensing component 100 is used to add a first calibrator into the reaction container and a second calibrator into the reaction container. The reagent dispensing component 200 is used to add reagents into different reaction containers, and the optical measurement component 300 is used to perform optical measurements on the reaction solution in the reaction container, which is made from at least one of the first and second calibrators and the reagents. The sample dispensing component 100 is mainly used to perform the function of dispensing calibrators and samples. The reagent dispensing component 200 is mainly used to perform the function of dispensing reagents. The optical measurement component 300 is mainly used to perform the function of optical measurement of the reaction solution.

[0149] As a first implementation of different detection parameters, when the different detection parameters include different components and / or different concentrations of reagents, the above-mentioned controlled sample measurement component performs a first sub-calibration process of a first item on multiple first calibrators containing target substances and having different concentrations of target substances, to obtain multiple first photometric results that correspond one-to-one with the multiple first calibrators. This includes performing the following process on the multiple first calibrators respectively: the controlled reagent dispensing component 200 adds the first reagent into the first reaction container; the controlled sample dispensing component 100 adds the first calibrator into the first reaction container; and the controlled photometric component 300 performs optical measurement on the first reaction liquid in the first reaction container, which is at least made of the first calibrator and the first reagent, to obtain the first photometric result. The aforementioned control sample measurement component performs a second sub-calibration process of the first item on multiple second calibrators containing target analytes at different concentrations, obtaining multiple second photometric results corresponding one-to-one with at least two second calibrators. This includes performing the following process on each of the multiple second calibrators: the control reagent dispensing component 200 adds a first reagent to a second reaction container; the control sample dispensing component 100 adds a second calibrator to a second reaction container; the control reagent dispensing component 200 adds a second reagent to a second reaction container; and the control photometric component 300 performs optical measurement on a second reaction solution in the second reaction container, which is at least composed of the second calibrator, the first reagent, and the second reagent, to obtain a second photometric result. The first reagent and the second reagent differ in at least one of the following: component and concentration. This embodiment innovatively proposes using reagents with different components and / or concentrations to react with calibrators or samples to obtain calibration curves with different concentration ranges, thereby broadening the measurable range of the sample analyzer. Its implementation is simple and can reduce the need for structural improvements to the sample analyzer. Furthermore, in this implementation scheme, the measurement cycle for different detection parameters is the same. Two different components and / or different concentrations of reagents in one set can complete two reactions, and the first reagent will not affect the subsequent reaction. Only the data from different stages are taken as the photometric results corresponding to the detection parameter. This is beneficial for using calibrators in overlapping areas within one measurement cycle to achieve the detection of different detection parameters, thereby reducing the number of calibrators.

[0150] Blank test points can be one of the following: immediately after the first reagent and calibrator are added, or immediately after the first reagent and sample are added; or after the first reagent and calibrator are added, or after the first reagent and sample are added, and before the second reagent is added; or after the first reagent is added, and before the calibrator or sample is added; or immediately after the first reagent and calibrator are added, and the second reagent is added, or immediately after the first reagent and sample are added, and the second reagent is added, and before the second reagent has fully reacted with the sample or calibrator.

[0151] The final test point for the sample can be one of the following: after adding the first reagent, calibrator, and second reagent and allowing them to react fully, or after adding the first reagent, sample, and second reagent and allowing them to react fully; or the end point of the measurement cycle.

[0152] Reference Figure 3 As shown, in a second implementation with different detection parameters, when the different detection parameters include different photometric components 300, the sample measurement assembly includes a first photometric component and a second photometric component, that is, the sample measurement assembly includes two photometric components 300, which are the first photometric component and the second photometric component, respectively. The above-mentioned control sample measurement assembly performs a first sub-calibration process of the first item on multiple first calibrators containing target substances with different concentrations of target substances, and obtains multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the first photometric component to perform optical measurement on the first reaction liquid in the first reaction vessel, which is at least made of the first calibrator and reagents, to obtain the first photometric result. The aforementioned control sample measurement component performs a second sub-calibration procedure of the first item on multiple second calibrators containing target analytes at different concentrations, obtaining multiple second photometric results corresponding one-to-one with at least two second calibrators. This includes performing the following procedure on each of the multiple second calibrators: controlling the second photometric component to perform optical measurements on the second reaction liquid in the second reaction vessel, which is at least composed of the second calibrators and reagents, to obtain second photometric results; wherein, one of the first and second photometric components is a transmission light detector, and the other is a scattering light detector. This embodiment, by setting different photometric components 300, achieves the purpose of broadening the measurement range of the sample analyzer, and is easy to implement.

[0153] Reference Figure 3As shown, in a third embodiment with different detection parameters, when the different detection parameters include reagents with different components and / or different concentrations and different photometric components 300, the sample measurement assembly includes a first photometric component and a second photometric component, that is, the sample measurement assembly includes two photometric components 300, which are the first photometric component and the second photometric component, respectively. The above-mentioned control sample measurement assembly performs a first sub-calibration process of the first item on multiple first calibrators containing target substances with different concentrations of target substances, and obtains multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the reagent dispensing component 200 to add the first reagent into the first reaction container; controlling the sample dispensing component 100 to add the first calibrator into the first reaction container; controlling the first photometric component to perform optical measurement on the first reaction liquid in the first reaction container, which is at least made of the first calibrator and the first reagent, to obtain the first photometric result. The aforementioned control sample measurement component performs a second sub-calibration procedure of the first item on multiple second calibrators containing target analytes with different concentrations, obtaining multiple second photometric results corresponding one-to-one with at least two second calibrators. This includes performing the following procedure on each of the multiple second calibrators: controlling the reagent dispensing component 200 to add a first reagent into a second reaction container; controlling the sample dispensing component 100 to add a second calibrator into a second reaction container; controlling the reagent dispensing component 200 to add a second reagent into a second reaction container; controlling the second photometric component to perform optical measurement on a second reaction solution in the second reaction container, which is at least composed of the second calibrator, the first reagent, and the second reagent, to obtain a second photometric result. The first reagent and the second reagent differ in at least one of the following: composition and concentration; one of the first photometric component and the second photometric component is a transmission light detector, and the other is a scattering light detector. This embodiment, by adding different reagents at different times during the measurement cycle and using different photometric components 300 to measure the reaction solution at different stages, can also broaden the measurable range of the sample analyzer.

[0154] In one implementation method, the optical measurement of the first reaction solution formed by the reaction of the first reagent and the calibrator is performed using turbidimetry; the optical measurement of the second reaction solution formed by the reaction of the second reagent and the calibrator is performed using colorimetry. Turbidimetry has high accuracy for detecting low concentrations, while colorimetry has high accuracy for detecting high concentrations.

[0155] In one implementation, the first optical measuring component is a scattered light detector, and the second optical measuring component is a transmitted light detector.

[0156] As a fourth implementation with different detection parameters, when the different detection parameters include light of different wavelengths, the aforementioned controlled sample measurement component performs a first sub-calibration procedure of the first item on multiple first calibrators containing target substances with different concentrations of target substances, obtaining multiple first photometric results corresponding one-to-one with the multiple first calibrators. This includes performing the following procedure on each of the multiple first calibrators: the controlled photometric component 300 performs optical measurement of a first reaction liquid in a first reaction vessel, which is made of at least the first calibrator and reagents, using a first wavelength of light, to obtain the first photometric result. The aforementioned controlled sample measurement component performs a second sub-calibration procedure of the first item on multiple second calibrators containing target substances with different concentrations of target substances, obtaining multiple second photometric results corresponding one-to-one with at least two second calibrators. This includes performing the following procedure on each of the multiple second calibrators: the controlled photometric component 300 performs optical measurement of a second reaction liquid in a second reaction vessel, which is made of at least the second calibrator and reagents, using a second wavelength of light, to obtain the second photometric result; wherein the wavelength of the second wavelength of light is greater than or less than the wavelength of the first wavelength of light. This embodiment, by setting different wavelengths of light to measure the reaction liquid, can also broaden the measurement range of the sample analyzer. Different wavelengths can be detected using a transmission light detector, or they can all be detected using a scattering light detector, or one wavelength can be detected using a transmission light detector and the other wavelength using a scattering light detector.

[0157] As a fifth implementation with different detection parameters, when the different detection parameters include different reaction times, the aforementioned controlled sample measurement component performs a first sub-calibration procedure of the first item on multiple first calibrators containing target analytes with different concentrations of target analytes, obtaining multiple first photometric results corresponding one-to-one with the multiple first calibrators. This includes performing the following procedure on each of the multiple first calibrators: the controlled photometric component 300 performs optical measurement on a first reaction solution prepared in a first reaction container by at least the first calibrator and reagent under the first reaction time, obtaining a first photometric result. The aforementioned controlled sample measurement component performs a second sub-calibration procedure of the first item on multiple second calibrators containing target analytes with different concentrations of target analytes, obtaining multiple second photometric results corresponding one-to-one with at least two second calibrators. This includes performing the following procedure on each of the multiple second calibrators: the controlled photometric component 300 performs optical measurement on a second reaction solution prepared in a second reaction container by at least the second calibrator and reagent under the second reaction time, obtaining a second photometric result; wherein the second reaction time is greater than or less than the first reaction time. This implementation, by setting different reaction times to measure the reaction solution, can also broaden the measurement range of the sample analyzer. Different reaction times can be detected using a transmitted light detector, or both can be detected using a scattered light detector, or one reaction time can be detected using a transmitted light detector and the other reaction time can be detected using a scattered light detector.

[0158] As a sixth implementation with different detection parameters, when the different detection parameters include different blank durations, the aforementioned control sample measurement component performs a first sub-calibration procedure of the first item on multiple first calibrators containing target analytes with different target analyte concentrations, obtaining multiple first photometric results corresponding one-to-one with the multiple first calibrators. This includes performing the following procedure on each of the multiple first calibrators: the control photometric component 300 performs optical measurement on a first reaction solution prepared in a first reaction vessel by at least the first calibrator and reagent under a first blank duration, obtaining a first photometric result. The aforementioned control sample measurement component performs a second sub-calibration procedure of the first item on multiple second calibrators containing target analytes with different target analyte concentrations, obtaining multiple second photometric results corresponding one-to-one with at least two second calibrators. This includes performing the following procedure on each of the multiple second calibrators: the control photometric component 300 performs optical measurement on a second reaction solution prepared in a second reaction vessel by at least the second calibrator and reagent under a second blank duration, obtaining a second photometric result; wherein the second blank duration is greater than or less than the first blank duration. This implementation, by setting different blank durations for measuring the reaction solution, can also broaden the measurement range of the sample analyzer. Different blank durations can all be detected using a transmitted light detector, or all can be detected using a scattered light detector, or one blank duration can be detected using a transmitted light detector and the other blank duration can be detected using a scattered light detector.

[0159] Reference Figure 2As shown, in one embodiment, generating a first calibration curve based on the concentration of the target analyte in multiple first calibrators, multiple first photometric results, the concentration of the target analyte in multiple second calibrators, and multiple second photometric results includes: generating a second calibration curve based on the concentration of the target analyte in multiple first calibrators and multiple first photometric results. The second calibration curve includes a first calibration curve L1 and a third calibration curve L3 that are interconnected. The abscissa values ​​of all points on the third calibration curve L3, except for the connection point with the first calibration curve L1, are greater than the abscissa values ​​of all points on the first calibration curve L1. The concentration of the target analyte and multiple second photometric results generate a third calibration curve. The third calibration curve includes two interconnected second calibration curves, L2 and L4. The x-coordinate values ​​of all points on the fourth calibration curve L4, except for the connection point with the second calibration curve L2, are smaller than the x-coordinate values ​​of all points on the second calibration curve L2. The third calibration curve is then shifted so that the connection point between the second calibration curve L2 and the fourth calibration curve L4 coincides with the connection point between the first calibration curve L1 and the third calibration curve L3. The third calibration curve L3 and the fourth calibration curve L4 are then deleted to obtain the first calibration curve. In practical applications, the connection points are obtained in advance and saved in the sample analyzer. When performing translation and splicing of calibration curves, only the connection points need to be spliced. The lower value calibration curve (i.e., the second calibration curve including the first calibration curve L1 and the third calibration curve L3) above the connection point (i.e., the third calibration curve L3) is deleted. The higher value calibration curve (i.e., the third calibration curve including the second calibration curve L2 and the fourth calibration curve L4) above the connection point (i.e., the fourth calibration curve L4) is also deleted.

[0160] In one implementation, one of the multiple first calibrators has a target analyte concentration of zero, and one of the multiple second calibrators also has a target analyte concentration of zero. The first calibrator with a target analyte concentration of zero and the second calibrator with a target analyte concentration of zero can be the same calibrator, such as deionized water, purified water, or distilled water. In this implementation, zero-point detection is required for different detection parameters.

[0161] In one implementation, the display is also used to show a project calibration management interface, which at least displays calibration management information for a first project. The first trigger command includes an instruction generated by an operator viewing the first project in the project calibration management interface via at least one of screen touch, mouse control, keyboard control, or voice input. In this implementation, the operator can access the calibration result interface from the project calibration management interface through human-computer interaction to view the calibration result of a specific project; the operation is simple.

[0162] In one implementation, the display is also used to display a second calibration result interface for the first item. The second calibration result interface displays at least a first calibration curve L1 and a second calibration curve L2 that are spaced apart and / or independently set. The controller 400 is further configured to: in response to a second trigger command, control the display to switch from displaying the first calibration result interface to displaying the second calibration result interface; and in response to a third trigger command, control the display to switch from displaying the second calibration result interface to displaying the first calibration result interface. The second trigger command includes an instruction formed by an operator performing an interface switching operation on the first calibration result interface through at least one of screen touch, mouse operation, keyboard operation, and voice input. The third trigger command includes an instruction formed by an operator performing an interface switching operation on the second calibration result interface through at least one of screen touch, mouse operation, keyboard operation, and voice input. In this implementation, the calibration result interface for the first item can switch display modes, displaying either a continuous calibration curve, two calibration curves before splicing that share the same horizontal axis, or two calibration curves in different coordinate systems (different horizontal and different vertical axes).

[0163] In one implementation, the first calibration result interface also displays a third ordinate. The first calibration curve also includes a fifth calibration curve segment. The first calibration curve segment L1, the second calibration curve segment L2, and the fifth calibration curve segment are sequentially connected to form a continuous curve. The horizontal axis X is also used to indicate the horizontal coordinate of the fifth calibration curve segment. The horizontal coordinate values ​​of all points on the fifth calibration curve segment, except for the connection point with the second calibration curve segment L2, are different from the horizontal coordinate values ​​of all points on the second calibration curve segment L2 and the first calibration curve segment L1. The third ordinate axis is used to indicate the vertical coordinate of the fifth calibration curve segment. Any two of the first ordinate axis Y1, the second ordinate axis Y2, and the third ordinate axis are spaced apart along the horizontal axis X, and any two of the first ordinate axis Y1, the second ordinate axis Y2, and the third ordinate axis have at least one difference in the following aspects: the range of scale values ​​and the meaning of the scale values. In this implementation, the first calibration curve of the first item is obtained by connecting three calibration curve segments, thereby further widening the measurement range. Of course, in specific applications, the first calibration curve of the first item can be obtained by connecting only two calibration curves, or it can be obtained by connecting four or more calibration curves.

[0164] In one implementation, the display information of the fifth calibration curve differs from that of the first calibration curve L1 and the second calibration curve L2 in at least one of the following: color, line type, line width, and identifier. That is, the three calibration curves are displayed differently, which facilitates the differentiation of different calibration curves.

[0165] In one implementation, the controller 400 is configured to: control the sample measurement component to perform a sample measurement procedure for the first item on the sample, obtaining a third optical measurement result and a fourth optical measurement result; obtain first measurement data based on the third optical measurement result and a first calibration curve L1; obtain second measurement data based on the fourth optical measurement result and a second calibration curve L2; and obtain the sample's detection result for the first item based on the first and second measurement data. In this implementation, during sample measurement, two sets of different measurement data are obtained using different detection parameters, and calibration is performed using different calibration curves. Then, the sample's detection result for the first item is obtained by comparing the data with a threshold.

[0166] In one embodiment, the sample dispensing component 100 includes a sample needle, a first suction and discharge power source for driving the suction and discharge action of the sample needle, and a first motion drive mechanism for driving the sample needle to perform spatial movement.

[0167] In one embodiment, the reagent dispensing component 200 includes a reagent needle, a first and second suction / dispensing power source for driving the reagent needle's suction and dispensing action, and a second motion drive mechanism for driving the reagent needle to perform spatial movement.

[0168] In one embodiment, the sample determination assembly also includes a reagent storage component 600 for storing reagent containers, and a reagent dispensing component 200 for drawing reagents from the reagent containers on the reagent storage component 600 and dispensing them into the reaction vessel.

[0169] In one embodiment, the reagent storage component 600 is disc-shaped, i.e., the reagent storage component 600 is a reagent tray. Of course, in specific applications, the reagent storage component 600 can also be other shapes.

[0170] In one embodiment, the sample determination assembly also includes a reaction support component 500, which supports the reaction container for the sample and reagents inside the reaction container to react.

[0171] In one embodiment, the reaction support component 500 is disc-shaped, that is, the reaction support component 500 is a reaction disk. Of course, in specific applications, the reaction support component 500 can also be other shapes.

[0172] In one embodiment, the photometric component 300 is used to perform optical measurements on the reaction liquid inside the reaction vessel on the reaction support component 500.

[0173] In one embodiment, the reagent dispensing component 200 is used to draw reagents from the reagent container on the reagent storage component 600 and dispense them into the reaction vessel located on the reaction support component 500.

[0174] In one embodiment, the sample dispensing component 100 is used to draw samples from a sample container and dispense them into a reaction container located on the reaction support component 500, and to draw calibrators from a calibrator container and dispense them into a reaction container located on the reaction support component 500.

[0175] In one embodiment, the sample determination assembly further includes an injection unit 700 for placing a sample container containing a sample to load the sample. A sample dispensing unit 100 is used to aspirate a sample from the sample container located in the injection unit 700 and dispense it into a reaction container located on the reaction support unit 500.

[0176] In one implementation, the sample analyzer is a biochemical analyzer, which can be used to detect biochemical items in samples. Of course, in specific applications, the sample analyzer can also be other types of analyzers, such as an immunoassay analyzer.

[0177] In practical applications, if multiple photometric components (300), reagents, methods, or reaction systems are involved in the same project, multiple calibration curves with different concentration ranges will be generated. This embodiment extracts the concentration range covered by each calibration curve, stitches them together, and displays their reactivity on the primary and secondary coordinate systems. To eliminate the differences in shape between the calibration curves fitted by different photometric components (300), reagents, methods, or reaction systems, the stitching points of multiple calibration curves are further smoothed mathematically. For example, the scale boundary range and precision unit of the secondary coordinate system are adjusted to achieve the visual effect of multiple calibration curves stitched into a single smooth curve. In addition, to more intuitively distinguish the concentration ranges corresponding to the reactivity on the primary and secondary coordinate systems, they can be differentiated by color, line width, or line type. That is, the color, line width, or line type of each calibration curve segment is consistent with the color, line width, and line type of the coordinate axis where its corresponding reactivity is located. Different segments of calibration curves corresponding to different reactions are distinguished by color, line width, or line type, thus solving the problem of how to simultaneously present multiple calibration curves with different reactivity range boundaries under the same coordinate system.

[0178] The sample analyzer provided in the second aspect of the present invention includes a sample measurement component and a controller 400. The sample measurement component is used to perform a calibration procedure of the first item on a calibrator containing a target analyte and having a known concentration of the target analyte; and to perform a sample measurement procedure of the first item on a sample for detecting the target analyte. The controller 400 is configured to perform the following calibration procedure of the first item: control the sample measurement component to perform a first sub-calibration procedure of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators; control the sample measurement component to perform a second sub-calibration procedure of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results corresponding one-to-one with at least two second calibrators; and output a continuous first calibration curve based on the concentration of the target analyte in the multiple first calibrators, the multiple first photometric results, the concentration of the target analyte in the multiple second calibrators, and the multiple second photometric results; wherein, at least one of the multiple second calibrators contains a target analyte with a concentration greater than that in the multiple first calibrators. The concentration of the target analyte is such that at least one of the second calibrators contains a concentration of the target analyte less than or equal to the concentration of the target analyte in at least one first calibrator. The sample measurement assembly includes a sample dispensing component 100, a reagent dispensing component 200, and an optical measurement component 300. The sample dispensing component 100 is used to add the first calibrator and the second calibrator to different reaction containers, respectively. The reagent dispensing component 200 is used to add reagents to different reaction containers. The optical measurement component 300 is used to perform optical measurements on the reaction solution in the reaction container, which is made of at least one of the first calibrator and the second calibrator and a reagent. The first optical measurement result and the second optical measurement result are obtained by the sample measurement assembly performing a first sub-calibration process of the first item on the first calibrator and a second sub-calibration process of the first item on the second calibrator using different detection parameters. The sample analyzer provided in the second aspect of the present invention differs from the first aspect in that it focuses on different aspects. Specifically, the first aspect focuses on limiting different segments of the calibration curves of the same item to be displayed as a continuous calibration curve in the same coordinate system and not sharing the vertical axis. In contrast, this embodiment focuses on limiting different detection parameters to obtain a continuous calibration curve.

[0179] In one implementation, a continuous first calibration curve is generated based on the concentration of the target analyte in multiple first calibrators, multiple first photometric results, the concentration of the target analyte in multiple second calibrators, and multiple second photometric results. This includes: generating a first calibration curve L1 based on the concentration of the target analyte in multiple first calibrators and multiple first photometric results; generating a second calibration curve L2 based on the concentration of the target analyte in multiple second calibrators and multiple second photometric results; and shifting the second calibration curve L2 so that it is joined with the first calibration curve L1 to form a continuous curve, thereby obtaining the first calibration curve.

[0180] As one implementation method, the different detection parameters mentioned above include any of the following: different components and / or different concentrations of reagents, different photometric components 300, different wavelengths of light, different reaction times, different blank times, and different methodologies (such as turbidimetry and colorimetry).

[0181] As a first implementation of different detection parameters, when the different detection parameters include different components and / or different concentrations of reagents, the above-mentioned controlled sample measurement component performs a first sub-calibration process of a first item on multiple first calibrators containing target substances and having different concentrations of target substances, to obtain multiple first photometric results that correspond one-to-one with the multiple first calibrators. This includes performing the following process on the multiple first calibrators respectively: the controlled reagent dispensing component 200 adds the first reagent into the first reaction container; the controlled sample dispensing component 100 adds the first calibrator into the first reaction container; and the controlled photometric component 300 performs optical measurement on the first reaction liquid in the first reaction container, which is at least made of the first calibrator and the first reagent, to obtain the first photometric result. The aforementioned control sample measurement component performs a second sub-calibration procedure of the first item on multiple second calibrators containing target analytes with different concentrations, obtaining multiple second photometric results corresponding one-to-one with at least two second calibrators. This includes performing the following procedure on each of the multiple second calibrators: the control reagent dispensing component 200 adds a first reagent to a second reaction container; the control sample dispensing component 100 adds a second calibrator to a second reaction container; the control reagent dispensing component 200 adds a second reagent to a second reaction container; and the control photometric component 300 performs optical measurement on a second reaction solution in the second reaction container, which is at least composed of the second calibrator, the first reagent, and the second reagent, to obtain a second photometric result. The first reagent and the second reagent differ in at least one of the following: composition and concentration. This embodiment, by changing the composition and / or concentration of the reagents, can obtain calibration curves with different concentration ranges, thereby broadening the measurable range of the sample analyzer. This method is simple and can reduce the need for structural modifications to the sample analyzer. Furthermore, in this implementation scheme, the measurement cycle for different detection parameters is the same, but data from different stages are taken as the photometric results corresponding to the detection parameter. This is beneficial for using calibrators in overlapping areas within one measurement cycle to achieve the detection of different detection parameters, thereby reducing the number of calibrators.

[0182] As a second implementation with different detection parameters, when the different detection parameters include different photometric components 300, the sample measurement assembly includes a first photometric component and a second photometric component. The above-mentioned control sample measurement assembly performs a first sub-calibration process of a first item on multiple first calibrators containing target substances with different concentrations of target substances, and obtains multiple first photometric results corresponding one-to-one with the multiple first calibrators. This includes performing the following process on the multiple first calibrators respectively: controlling the first photometric component to perform optical measurement on a first reaction liquid in a first reaction vessel made of at least the first calibrator and reagents, and obtaining the first photometric result. The above-mentioned control sample measurement assembly performs a second sub-calibration process of the first item on multiple second calibrators containing target substances with different concentrations of target substances, and obtains multiple second photometric results corresponding one-to-one with at least two second calibrators. This includes performing the following process on the multiple second calibrators respectively: controlling the second photometric component to perform optical measurement on a second reaction liquid in a second reaction vessel made of at least the second calibrator and reagents, and obtaining the second photometric result; wherein, one of the first photometric component and the second photometric component is a transmission light detector, and the other is a scattering light detector. This implementation scheme expands the measurement range of the sample analyzer by setting different photometric components 300, and is easy to implement.

[0183] As a third implementation with different detection parameters, when the different detection parameters include different components and / or reagents of different concentrations and different photometric components 300, the sample measurement assembly includes a first photometric component and a second photometric component. The above-mentioned controlled sample measurement assembly performs a first sub-calibration process of a first item on multiple first calibrators containing target analytes with different concentrations of target analytes, obtaining multiple first photometric results corresponding one-to-one with the multiple first calibrators. This includes performing the following process on each of the multiple first calibrators: controlling the reagent dispensing component 200 to add the first reagent into the first reaction container; controlling the sample dispensing component 100 to add the first calibrator into the first reaction container; controlling the first photometric component to perform optical measurement on the first reaction solution in the first reaction container, which is at least composed of the first calibrator and the first reagent, to obtain the first photometric result. The aforementioned control sample measurement component performs a second sub-calibration procedure of the first item on multiple second calibrators containing target analytes with different concentrations, obtaining multiple second photometric results corresponding one-to-one with at least two second calibrators. This includes performing the following procedure on each of the multiple second calibrators: controlling the reagent dispensing component 200 to add a first reagent into a second reaction container; controlling the sample dispensing component 100 to add a second calibrator into a second reaction container; controlling the reagent dispensing component 200 to add a second reagent into a second reaction container; controlling the second photometric component to perform optical measurement on a second reaction solution in the second reaction container, which is at least composed of the second calibrator, the first reagent, and the second reagent, to obtain a second photometric result. The first reagent and the second reagent differ in at least one of the following: composition and concentration; one of the first photometric component and the second photometric component is a transmission light detector, and the other is a scattering light detector. This embodiment, by adding different reagents at different times during the measurement cycle and using different photometric components 300 to measure the reaction solution at different stages, can also broaden the measurable range of the sample analyzer.

[0184] As a fourth implementation with different detection parameters, when the different detection parameters include light of different wavelengths, the aforementioned controlled sample measurement component performs a first sub-calibration procedure of the first item on multiple first calibrators containing target substances with different concentrations of target substances, obtaining multiple first photometric results corresponding one-to-one with the multiple first calibrators. This includes performing the following procedure on each of the multiple first calibrators: the controlled photometric component 300 performs optical measurement of a first reaction liquid in a first reaction vessel, which is made of at least the first calibrator and reagents, using a first wavelength of light, to obtain the first photometric result. The aforementioned controlled sample measurement component performs a second sub-calibration procedure of the first item on multiple second calibrators containing target substances with different concentrations of target substances, obtaining multiple second photometric results corresponding one-to-one with at least two second calibrators. This includes performing the following procedure on each of the multiple second calibrators: the controlled photometric component 300 performs optical measurement of a second reaction liquid in a second reaction vessel, which is made of at least the second calibrator and reagents, using a second wavelength of light, to obtain the second photometric result; wherein the wavelength of the second wavelength of light is greater than or less than the wavelength of the first wavelength of light. This embodiment, by setting different wavelengths of light to measure the reaction liquid, can also broaden the measurement range of the sample analyzer. Different wavelengths can be detected using a transmission light detector, or they can all be detected using a scattering light detector, or one wavelength can be detected using a transmission light detector and the other wavelength using a scattering light detector.

[0185] As a fifth implementation with different detection parameters, when the different detection parameters include different reaction times, the aforementioned controlled sample measurement component performs a first sub-calibration procedure of the first item on multiple first calibrators containing target analytes with different concentrations of target analytes, obtaining multiple first photometric results corresponding one-to-one with the multiple first calibrators. This includes performing the following procedure on each of the multiple first calibrators: the controlled photometric component 300 performs optical measurement on a first reaction solution prepared in a first reaction container by at least the first calibrator and reagent under the first reaction time, obtaining a first photometric result. The aforementioned controlled sample measurement component performs a second sub-calibration procedure of the first item on multiple second calibrators containing target analytes with different concentrations of target analytes, obtaining multiple second photometric results corresponding one-to-one with at least two second calibrators. This includes performing the following procedure on each of the multiple second calibrators: the controlled photometric component 300 performs optical measurement on a second reaction solution prepared in a second reaction container by at least the second calibrator and reagent under the second reaction time, obtaining a second photometric result; wherein the second reaction time is greater than or less than the first reaction time. This implementation, by setting different reaction times to measure the reaction solution, can also broaden the measurement range of the sample analyzer. Different reaction times can be detected using a transmitted light detector, or both can be detected using a scattered light detector, or one reaction time can be detected using a transmitted light detector and the other reaction time can be detected using a scattered light detector.

[0186] As a sixth implementation with different detection parameters, when the different detection parameters include different blank durations, the aforementioned control sample measurement component performs a first sub-calibration procedure of the first item on multiple first calibrators containing target analytes with different target analyte concentrations, obtaining multiple first photometric results corresponding one-to-one with the multiple first calibrators. This includes performing the following procedure on each of the multiple first calibrators: the control photometric component 300 performs optical measurement on a first reaction solution prepared in a first reaction vessel by at least the first calibrator and reagent under a first blank duration, obtaining a first photometric result. The aforementioned control sample measurement component performs a second sub-calibration procedure of the first item on multiple second calibrators containing target analytes with different target analyte concentrations, obtaining multiple second photometric results corresponding one-to-one with at least two second calibrators. This includes performing the following procedure on each of the multiple second calibrators: the control photometric component 300 performs optical measurement on a second reaction solution prepared in a second reaction vessel by at least the second calibrator and reagent under a second blank duration, obtaining a second photometric result; wherein the second blank duration is greater than or less than the first blank duration. This implementation, by setting different blank durations for measuring the reaction solution, can also broaden the measurement range of the sample analyzer. Different blank durations can all be detected using a transmitted light detector, or all can be detected using a scattered light detector, or one blank duration can be detected using a transmitted light detector and the other blank duration can be detected using a scattered light detector.

[0187] Apart from the above, other parts and principles of the sample analyzer provided in the second aspect of the present invention can be referred to the first aspect above, and will not be described in detail here.

[0188] The sample analyzer provided in the third aspect of the present invention includes a sample measurement component, a display, and a controller 400. The sample measurement component is used to perform a calibration procedure for a first item on a calibrator containing a target analyte and whose concentration is known; and to perform a sample measurement procedure for a sample used to detect the target analyte. The display is used to display at least a first calibration result interface for the first item. The controller 400 is configured to control the display to display the first calibration result interface in response to a first trigger command. The first calibration result interface displays at least a first calibration curve for the first item. The first calibration curve includes a first calibration curve L1 generated based on a first photometric result and a second calibration curve L2 generated based on a second photometric result. The first photometric result and the second photometric result are obtained by the sample measurement component performing the calibration procedure for the first item on the calibrator using different detection parameters. The first calibration curve L1 and the second calibration curve L2 are connected to form a continuous curve, and the first calibration curve L1 and the second calibration curve L2 have different display information in at least one of the following: color, line type, line width, and identifier. The sample analyzer provided in the third aspect of the present invention differs from the first aspect in that it focuses on different aspects. Specifically, the first aspect focuses on limiting different segments of calibration curves of the same item to be displayed as a continuous calibration curve in the same coordinate system and not sharing the same vertical axis; while this embodiment focuses on limiting different segments of calibration curves obtained by different detection parameters to be displayed on the same interface with different display information and connected as a continuous calibration curve.

[0189] Apart from the above, other parts and principles of the sample analyzer provided in the third aspect of the present invention can be referred to the first aspect above, and will not be described in detail here.

[0190] The above description is merely a preferred embodiment of the present invention and does not limit the patent scope of the present invention. Any equivalent structural transformations made using the contents of the present invention's specification and drawings under the inventive concept of the present invention, or direct / indirect applications in other related technical fields, are included within the patent protection scope of the present invention.

Claims

1. A sample analyzer, characterized in that: include: A sample measurement assembly for performing a calibration procedure for a first item on a calibrator containing a target analyte and the concentration of the target analyte is known. And a sample measurement procedure for performing the first item on a sample used to detect the target analyte; A display, the display being used at least to display a first calibration result interface for the first item; A controller configured to, in response to a first trigger command, control the display to show the first calibration result interface; The first calibration result interface displays at least a horizontal axis, a first vertical axis, a second vertical axis, and a first calibration curve for the first item. The first calibration curve includes a first calibration curve segment and a second calibration curve segment, which are connected to form a continuous curve. The horizontal axis indicates the horizontal coordinate of the first calibration curve segment and the horizontal coordinate of the second calibration curve segment. The horizontal coordinate values ​​of all points on the first calibration curve segment, except for the connection point connecting to the second calibration curve segment, are either less than or greater than the horizontal coordinate values ​​of all points on the second calibration curve segment. The first vertical axis indicates the vertical coordinate of the first calibration curve segment, and the second vertical axis indicates the vertical coordinate of the second calibration curve segment. The first vertical axis and the second vertical axis are spaced apart along the horizontal axis, and the first vertical axis and the second vertical axis differ in at least one of the following: the range of scale values ​​and the meaning of the scale values. Alternatively, the first calibration result interface may display at least the first calibration curve of the first item. The first calibration curve includes a first segment calibration curve generated based on the first photometric result and a second segment calibration curve generated based on the second photometric result. The first photometric result and the second photometric result are obtained by the sample measurement component performing the calibration process of the first item on the calibrator using different detection parameters. The first segment calibration curve and the second segment calibration curve are connected to form a continuous curve, and the first segment calibration curve and the second segment calibration curve have different display information in at least one of the following: color, line type, line width, and identifier.

2. The sample analyzer as described in claim 1, characterized in that: The first calibration result interface displays at least the horizontal axis, the first vertical axis, the second vertical axis, and the first calibration curve of the first item, and the first calibration curve and the second calibration curve have different display information in at least one of the following: color, line type, line width, and identifier.

3. The sample analyzer as described in claim 2, characterized in that: The color, line type, and line width of the first calibration curve are consistent with the color, line type, and line width of the first vertical axis, respectively; the color, line type, and line width of the second calibration curve are consistent with the color, line type, and line width of the second vertical axis, respectively. And / or, the first calibration curve segment and the first vertical axis both have the same first identifier, and the second calibration curve segment and the second vertical axis both have the same second identifier.

4. The sample analyzer according to any one of claims 1 to 3, characterized in that: The first calibration result interface displays at least the horizontal axis, the first vertical axis, the second vertical axis, and the first calibration curve of the first item, and the first calibration curve and the second calibration curve are located between the first vertical axis and the second vertical axis in the direction parallel to the horizontal axis; And / or, the first calibration result interface displays at least the horizontal axis, the first vertical axis, the second vertical axis, and the first calibration curve of the first item, wherein the horizontal axis is used to indicate the scale value used to characterize the concentration, the first vertical axis is used to indicate the scale value used to characterize the reactivity or absorbance or luminescence value, and the second vertical axis is used to indicate the scale value used to characterize the reactivity or absorbance or luminescence value.

5. The sample analyzer according to any one of claims 1 to 3, characterized in that: The first calibration result interface displays at least the horizontal axis, the first vertical axis, the second vertical axis, and the first calibration curve of the first item. The horizontal coordinate values ​​of all points on the first calibration curve, except for the connection points connected to the second calibration curve, are smaller than the horizontal coordinate values ​​of all points on the second calibration curve. The scale value range of the first vertical axis is larger than the scale value range of the second vertical axis. And / or, the connection between the first calibration curve segment and the second calibration curve segment is a smooth transition.

6. The sample analyzer as described in claim 1, characterized in that: The controller is also configured to perform the following calibration procedure for the first item: The sample measurement component is controlled to perform the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, thereby obtaining multiple first photometric results that correspond one-to-one with the multiple first calibrators; The sample measurement component is controlled to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, thereby obtaining multiple second photometric results that correspond one-to-one with the at least two second calibrators; The first calibration curve is generated based on the concentration of the target analyte in the plurality of first calibrators, the plurality of first photometric results, the concentration of the target analyte in the plurality of second calibrators, and the plurality of second photometric results; Wherein, at least one of the plurality of second calibrators contains a concentration of the target analyte greater than the concentration of the target analyte in the plurality of first calibrators, and at least another of the plurality of second calibrators contains a concentration of the target analyte less than or equal to the concentration of the target analyte in at least one of the first calibrators; The first optical measurement result and the second optical measurement result are obtained by the sample measurement component performing the first sub-calibration process of the first item on the first calibrator and the second sub-calibration process of the first item on the second calibrator using different detection parameters.

7. The sample analyzer as described in claim 6, characterized in that: The step of generating the first calibration curve based on the concentration of the target analyte in the plurality of first calibrators, the plurality of first photometric results, the concentration of the target analyte in the plurality of second calibrators, and the plurality of second photometric results includes: The first calibration curve is generated based on the concentration of the target analyte in the plurality of first calibrators and the plurality of first photometric results. The second calibration curve is generated based on the concentration of the target analyte in the plurality of second calibrators and the plurality of second photometric results. The second calibration curve is shifted so that it is joined with the first calibration curve to form a continuous curve, thus obtaining the first calibration curve.

8. The sample analyzer as described in claim 7, characterized in that: After the second calibration curve is translated to form a continuous curve by splicing the second calibration curve with the first calibration curve, the controller is further configured to scale the second calibration curve and the second ordinate to make the connection between the first calibration curve and the second calibration curve a smooth transition.

9. The sample analyzer according to any one of claims 6 to 8, characterized in that: The sample measurement assembly includes a sample dispensing component, a reagent dispensing component, and an optical measurement component. The sample dispensing component is used to add the first calibrator and the second calibrator into different reaction containers, respectively. The reagent dispensing component is used to add reagents into the different reaction containers. The optical measurement component is used to perform optical measurement on the reaction solution in the reaction container, which is made of at least one of the first calibrator and the second calibrator and the reagent. The different detection parameters include any of the following: different components and / or different concentrations of reagents, different photometric components, different wavelengths of light, different reaction times, and different blank times.

10. The sample analyzer as described in claim 9, characterized in that: When the different detection parameters include reagents with different components and / or different concentrations, the control of the sample measurement component performs the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and with different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: The reagent dispensing component is controlled to add the first reagent into the first reaction vessel; The sample dispensing component is controlled to add the first calibrator into the first reaction vessel; The optical measurement component is controlled to perform optical measurement on the first reaction liquid in the first reaction container, which is made of at least the first calibrator and the first reagent, to obtain the first optical measurement result; The control of the sample measurement component performs a second sub-calibration process of the first item on multiple second calibrators containing the target analyte and with different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: The reagent dispensing component is controlled to add the first reagent into the second reaction vessel; The sample dispensing component is controlled to add the second calibrator into the second reaction vessel; The reagent dispensing component is controlled to add the second reagent into the second reaction vessel; The optical measurement component is controlled to perform optical measurement on the second reaction liquid in the second reaction vessel, which is made of at least the second calibrator, the first reagent and the second reagent, to obtain the second optical measurement result; Wherein, the first reagent and the second reagent differ in at least one of the following: components and concentrations; Alternatively, when the different detection parameters include different photometric components, the sample measurement assembly includes a first photometric component and a second photometric component. The control of the sample measurement assembly to perform a first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results that correspond one-to-one with the multiple first calibrators, includes performing the following process on the multiple first calibrators respectively: controlling the first photometric component to perform optical measurement on a first reaction liquid in a first reaction vessel made of at least the first calibrator and reagents, to obtain the first photometric result; The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the second photometric component to perform optical measurement on the second reaction liquid in the second reaction vessel, which is at least made of the second calibrator and reagents, to obtain the second photometric result; Among them, one of the first optical measurement component and the second optical measurement component is a transmission light detector, and the other is a scattering light detector; Alternatively, when the different detection parameters include reagents with different components and / or different concentrations and different photometric components, the sample measurement assembly includes a first photometric component and a second photometric component; The control of the sample measurement component to perform a first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the reagent dispensing component to add a first reagent into a first reaction container; controlling the sample dispensing component to add the first calibrator into the first reaction container; controlling the first photometric component to perform optical measurement on a first reaction solution in the first reaction container made of at least the first calibrator and the first reagent, to obtain the first photometric result; The control of the sample measurement component to perform a second sub-calibration process of the first item on multiple second calibrators containing the target analyte and with different concentrations of the target analyte, to obtain multiple second photometric results corresponding one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the reagent dispensing component to add a first reagent into a second reaction container; controlling the sample dispensing component to add a second calibrator into a second reaction container; controlling the reagent dispensing component to add a second reagent into a second reaction container; controlling the second photometric component to perform optical measurement on a second reaction solution in the second reaction container made of at least the second calibrator, the first reagent, and the second reagent, to obtain the second photometric result; Wherein, the first reagent and the second reagent differ in at least one of the following: components and concentrations; One of the first optical measurement component and the second optical measurement component is a transmitted light detector, and the other is a scattered light detector; Alternatively, when the different detection parameters include light of different wavelengths, the control of the sample measurement component performs the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the photometric component to perform optical measurement of light of the first wavelength on the first reaction liquid in the first reaction container, which is made of at least the first calibrator and the reagent, to obtain the first photometric result; The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the photometric component to perform optical measurement of a second wavelength of light on a second reaction liquid in a second reaction vessel made of at least the second calibrator and reagents, to obtain the second photometric result; Wherein, the wavelength of the second wavelength light is greater than or less than the wavelength of the first wavelength light; Alternatively, when the different detection parameters include different reaction times, the control of the sample measurement component performs the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results that correspond one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the photometric component to perform optical measurement on the first reaction liquid in the first reaction container, which is at least made of the first calibrator and reagent under the first reaction time, to obtain the first photometric result; The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the photometric component to perform optical measurement on the second reaction liquid in the second reaction vessel, which is at least made of the second calibrator and reagent under the second reaction time, to obtain the second photometric result; Wherein, the second reaction time is greater than or less than the first reaction time; Alternatively, when the different detection parameters include different blank durations, the control of the sample measurement component to perform the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the photometric component to perform optical measurement on the first reaction liquid in the first reaction vessel prepared by at least the first calibrator and reagent under the first blank duration, to obtain the first photometric result; The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the photometric component to perform optical measurement on the second reaction liquid prepared in the second reaction vessel by at least the second calibrator and reagent under the second blank time, to obtain the second photometric result; Wherein, the second blank duration is greater than or less than the first blank duration.

11. The sample analyzer according to any one of claims 6 to 8, characterized in that: The step of generating the first calibration curve based on the concentration of the target analyte in the plurality of first calibrators, the plurality of first photometric results, the concentration of the target analyte in the plurality of second calibrators, and the plurality of second photometric results includes: generating a second calibration curve based on the concentration of the target analyte in the plurality of first calibrators and the plurality of first photometric results; the second calibration curve includes a first calibration curve segment and a third calibration curve segment connected to each other; the abscissa value of all points on the third calibration curve segment, except for the connection point with the first calibration curve segment, is greater than the abscissa value of all points on the first calibration curve segment; based on the concentration of the target analyte in the plurality of second calibrators, the first calibration curve segment is generated based on the concentration of the target analyte in the plurality of first calibrators and the plurality of first photometric results. Based on the concentration of the target analyte and the multiple second photometric results, a third calibration curve is generated. The third calibration curve includes two interconnected calibration curve segments: a second calibration curve segment and a fourth calibration curve segment. The abscissa values ​​of all points on the fourth calibration curve segment, except for the connection point with the second calibration curve segment, are smaller than the abscissa values ​​of all points on the second calibration curve segment. The third calibration curve segment is then shifted so that the connection point between the second and fourth calibration curve segments coincides with the connection point between the first and third calibration curve segments. Finally, the third and fourth calibration curve segments are deleted to obtain the first calibration curve. And / or, in one of the plurality of first calibrators, the concentration of the target analyte in the first calibrator is equal to zero, and in one of the plurality of second calibrators, the concentration of the target analyte in the second calibrator is equal to zero.

12. The sample analyzer according to any one of claims 1 to 3 or any one of claims 6 to 8, characterized in that: The display is also used to display a second calibration result interface for the first item, wherein the second calibration result interface displays at least the first calibration curve segment and the second calibration curve segment set at intervals and / or independently of each other; the controller is also configured to: in response to a second trigger command, control the display to switch from displaying the first calibration result interface to displaying the second calibration result interface. In response to a third trigger command, the display is controlled to switch from displaying the second calibration result interface to displaying the first calibration result interface; wherein, the second trigger command includes: an instruction formed by an operator performing an interface switching operation on the first calibration result interface through at least one of screen touch, mouse operation, keyboard operation, and voice input; the third trigger command includes: an instruction formed by an operator performing an interface switching operation on the second calibration result interface through at least one of screen touch, mouse operation, keyboard operation, and voice input; And / or, the display is also used to display a project calibration management interface, which at least displays calibration management information for the first project; the first trigger instruction includes: an instruction formed by an operator viewing the first project in the project calibration management interface through at least one of screen touch, mouse operation, keyboard operation, and voice input.

13. The sample analyzer according to any one of claims 1 to 3 or any one of claims 6 to 8, characterized in that: The first calibration result interface displays at least the horizontal axis, the first vertical axis, the second vertical axis, and the first calibration curve of the first item. The first calibration result interface also displays a third vertical axis. The first calibration curve also includes a fifth calibration curve. The first calibration curve, the second calibration curve, and the fifth calibration curve are connected in sequence to form a continuous curve. The horizontal axis is also used to indicate the horizontal coordinate of the fifth calibration curve. The horizontal coordinate values ​​of all points on the fifth calibration curve, except for the connection point connected to the second calibration curve, are different from the horizontal coordinate values ​​of the points on the second calibration curve and the horizontal coordinate values ​​of the points on the first calibration curve. The third vertical axis is used to indicate the vertical coordinate of the fifth calibration curve. Any two of the first, second, and third vertical axes are spaced apart along the horizontal axis, and any two of the first, second, and third vertical axes have at least one difference in the following aspects: the range of scale values ​​and the meaning of the scale values. Preferably, the display information of the fifth calibration curve is different from the display information of the first calibration curve and the display information of the second calibration curve in at least one of the following: color, line type, line width, and identifier.

14. The sample analyzer according to any one of claims 1 to 3 or any one of claims 6 to 8, characterized in that: The controller is configured to control the sample measurement component to perform the sample measurement process of the first item on the sample to obtain the third optical measurement result and the fourth optical measurement result; Based on the third photometric result and the first calibration curve, the first measurement data is obtained; Based on the fourth photometric result and the second calibration curve, the second measurement data is obtained; Based on the first measurement data and the second measurement data, the test results of the sample regarding the first item are obtained.

15. A sample analyzer, characterized in that: include: A sample measurement assembly for performing a calibration procedure for a first item on a calibrator containing a target analyte and the concentration of the target analyte is known. And a sample measurement procedure for performing the first item on a sample used to detect the target analyte; The controller is configured to perform the following calibration procedure for the first item: The sample measurement component is controlled to perform the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, thereby obtaining multiple first photometric results that correspond one-to-one with the multiple first calibrators; The sample measurement component is controlled to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, thereby obtaining multiple second photometric results that correspond one-to-one with the at least two second calibrators; Based on the concentration of the target analyte in the plurality of first calibrators, the plurality of first photometric results, the concentration of the target analyte in the plurality of second calibrators, and the plurality of second photometric results, a continuous first calibration curve is output; Wherein, at least one of the plurality of second calibrators contains a concentration of the target analyte greater than the concentration of the target analyte in the plurality of first calibrators, and at least another of the plurality of second calibrators contains a concentration of the target analyte less than or equal to the concentration of the target analyte in at least one of the first calibrators; The sample measurement assembly includes a sample dispensing component, a reagent dispensing component, and an optical measurement component. The sample dispensing component is used to add the first calibrator and the second calibrator into different reaction containers, respectively. The reagent dispensing component is used to add reagents into the different reaction containers. The optical measurement component is used to perform optical measurement on the reaction solution in the reaction container, which is made of at least one of the first calibrator and the second calibrator and the reagent. The first optical measurement result and the second optical measurement result are obtained by the sample measurement component performing the first sub-calibration process of the first item on the first calibrator and the second sub-calibration process of the first item on the second calibrator using different detection parameters.

16. The sample analyzer as described in claim 15, characterized in that: The step of generating a continuous first calibration curve based on the concentration of the target analyte in the plurality of first calibrators, the plurality of first photometric results, the concentration of the target analyte in the plurality of second calibrators, and the plurality of second photometric results includes: A first calibration curve is generated based on the concentration of the target analyte in the plurality of first calibrators and the plurality of first photometric results; A second calibration curve is generated based on the concentration of the target analyte in the plurality of second calibrators and the plurality of second photometric results; The second calibration curve is shifted so that it is joined with the first calibration curve to form a continuous curve, thus obtaining the first calibration curve.

17. The sample analyzer as described in claim 15 or 16, characterized in that: The different detection parameters include any of the following: different components and / or different concentrations of reagents, different photometric components, different wavelengths of light, different reaction times, and different blank times.

18. The sample analyzer as described in claim 17, characterized in that: When the different detection parameters include reagents with different components and / or different concentrations, the control of the sample measurement component performs the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and with different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: The reagent dispensing component is controlled to add the first reagent into the first reaction vessel; The sample dispensing component is controlled to add the first calibrator into the first reaction vessel; The optical measurement component is controlled to perform optical measurement on the first reaction liquid in the first reaction container, which is made of at least the first calibrator and the first reagent, to obtain the first optical measurement result; The control of the sample measurement component performs a second sub-calibration process of the first item on multiple second calibrators containing the target analyte and with different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: The reagent dispensing component is controlled to add the first reagent into the second reaction vessel; The sample dispensing component is controlled to add the second calibrator into the second reaction vessel; The reagent dispensing component is controlled to add the second reagent into the second reaction vessel; The optical measurement component is controlled to perform optical measurement on the second reaction liquid in the second reaction vessel, which is made of at least the second calibrator, the first reagent and the second reagent, to obtain the second optical measurement result; Wherein, the first reagent and the second reagent differ in at least one of the following: components and concentrations; Alternatively, when the different detection parameters include different photometric components, the sample measurement assembly includes a first photometric component and a second photometric component. The control of the sample measurement assembly to perform a first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results that correspond one-to-one with the multiple first calibrators, includes performing the following process on the multiple first calibrators respectively: controlling the first photometric component to perform optical measurement on a first reaction liquid in a first reaction vessel made of at least the first calibrator and reagents, to obtain the first photometric result; The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the second photometric component to perform optical measurement on the second reaction liquid in the second reaction vessel, which is at least made of the second calibrator and reagents, to obtain the second photometric result; Among them, one of the first optical measurement component and the second optical measurement component is a transmission light detector, and the other is a scattering light detector; Alternatively, when the different detection parameters include reagents with different components and / or different concentrations and different photometric components, the sample measurement assembly includes a first photometric component and a second photometric component. Controlling the sample measurement assembly to perform a first sub-calibration process of the first item on multiple first calibrators containing the target analyte and with different concentrations of the target analyte, yielding multiple first photometric results corresponding one-to-one with the multiple first calibrators, includes performing the following process on each of the multiple first calibrators: The reagent dispensing component is controlled to add the first reagent into the first reaction vessel; The sample dispensing component is controlled to add the first calibrator into the first reaction vessel; The first optical measurement component is controlled to perform optical measurement on the first reaction liquid in the first reaction container, which is made of at least the first calibrator and the first reagent, to obtain the first optical measurement result; The control of the sample measurement component performs a second sub-calibration process of the first item on multiple second calibrators containing the target analyte and with different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: The reagent dispensing component is controlled to add the first reagent into the second reaction vessel; The sample dispensing component is controlled to add the second calibrator into the second reaction vessel; The reagent dispensing component is controlled to add the second reagent into the second reaction vessel; The second photometric component is controlled to perform optical measurements on the second reaction liquid in the second reaction vessel, which is made of at least the second calibrator, the first reagent and the second reagent, to obtain the second photometric result. Wherein, the first reagent and the second reagent differ in at least one of the following: components and concentrations; One of the first optical measurement component and the second optical measurement component is a transmitted light detector, and the other is a scattered light detector; Alternatively, when the different detection parameters include light of different wavelengths, the control of the sample measurement component performs the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the photometric component to perform optical measurement of light of the first wavelength on the first reaction liquid in the first reaction container, which is made of at least the first calibrator and the reagent, to obtain the first photometric result; The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the photometric component to perform optical measurement of a second wavelength of light on a second reaction liquid in a second reaction vessel made of at least the second calibrator and reagents, to obtain the second photometric result; Wherein, the wavelength of the second wavelength light is greater than or less than the wavelength of the first wavelength light; Alternatively, when the different detection parameters include different reaction times, the control of the sample measurement component performs the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results that correspond one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the photometric component to perform optical measurement on the first reaction liquid in the first reaction container, which is at least made of the first calibrator and reagent under the first reaction time, to obtain the first photometric result; The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the photometric component to perform optical measurement on the second reaction liquid in the second reaction vessel, which is at least made of the second calibrator and reagent under the second reaction time, to obtain the second photometric result; Wherein, the second reaction time is greater than or less than the first reaction time; Alternatively, when the different detection parameters include different blank durations, the control of the sample measurement component to perform the first sub-calibration process of the first item on multiple first calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple first photometric results corresponding one-to-one with the multiple first calibrators, including performing the following process on the multiple first calibrators respectively: controlling the photometric component to perform optical measurement on the first reaction liquid in the first reaction vessel prepared by at least the first calibrator and reagent under the first blank duration, to obtain the first photometric result; The control of the sample measurement component to perform the second sub-calibration process of the first item on multiple second calibrators containing the target analyte and having different concentrations of the target analyte, to obtain multiple second photometric results that correspond one-to-one with the at least two second calibrators, including performing the following process on the multiple second calibrators respectively: controlling the photometric component to perform optical measurement on the second reaction liquid prepared in the second reaction vessel by at least the second calibrator and reagent under the second blank time, to obtain the second photometric result; Wherein, the second blank duration is greater than or less than the first blank duration.

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