A toxin detection device for food and medicine

Abstract

This invention discloses a toxin detection device for food and pharmaceuticals, belonging to the field of biological detection technology. It includes a support base and a detection tube mounted on the support base. The detection tube has an upward-facing opening and its axis is parallel to the vertical direction. A sealing plate is installed at the opening of the detection tube. A central tube is coaxially rotatably mounted on the inner side of the detection tube. The upper end of the central tube passes through the sealing plate and is connected to a rotation drive device. An agitator and a defoaming device are simultaneously connected to the outer side of the central tube. A first float is slidably fitted on the outer side of the central tube, located between the agitator and the defoaming device. The first float has a cylindrical structure, and its outer wall slides and seals against the inner wall of the detection tube. A central channel is formed in the center of the central tube. An air inlet and an air outlet are opened on the wall of the central tube, located on the upper and lower sides of the first float, respectively. This invention can reduce air bubbles generated during reagent production and improve the accuracy of toxin detection results.

Description

Technical Field

[0001] This invention belongs to the field of biological detection technology, specifically relating to a toxin detection device for food and pharmaceuticals. Background Technology

[0002] Existing food and drug toxin detection equipment generates a large amount of foam during reagent addition and mixing due to mechanical stirring or liquid impact, leading to inaccurate sample concentration. Specifically, toxin molecules, as surfactants, tend to accumulate at the gas-liquid interface and are encapsulated by foam, resulting in a decrease in the actual concentration of the analyte in the liquid phase and affecting the accuracy of quantitative analysis. Summary of the Invention

[0003] In view of this, the purpose of the present invention is to provide a toxin detection device for food and pharmaceuticals, which can reduce the bubbles generated by reagents during the production process and improve the accuracy of toxin detection results.

[0004] To achieve the above objectives, the present invention provides the following technical solution: This invention discloses a toxin detection device for food and pharmaceuticals, comprising a support base and a detection tube mounted on the support base. The opening of the detection tube faces upward and its axis is parallel to the vertical direction. A sealing plate is installed at the opening of the detection tube. A central tube is coaxially and rotatably mounted on the inner side of the detection tube. The upper end of the central tube passes through the sealing plate and is connected to a rotation drive device. An agitation device and a defoaming device are simultaneously connected to the outer side of the central tube. A first float is slidably sleeved on the outer side of the central tube. The first float is located between the agitation device and the defoaming device. The first float has a cylindrical structure, and its outer side wall is slidably sealed with the inner side wall of the detection tube. A central channel is formed in the center of the central tube. An air inlet and an air outlet are opened on the tube wall of the central tube. The air outlet and the air inlet are located on the upper and lower sides of the first float, respectively. A liquid inlet and a liquid outlet are opened on the side wall of the detection tube. The liquid inlet and the liquid outlet are connected through a reflux channel. The liquid inlet and the liquid outlet are located on the upper and lower sides of the first float, respectively.

[0005] Furthermore, a delivery pump and a defoaming screen are installed in the central channel. The delivery pump is used to transport the air bubbles from the inlet to the outlet, and the defoaming screen is located below the delivery pump. The defoaming device breaks up the air bubbles after rotating.

[0006] Furthermore, the defoaming device includes an eccentric column, an upper top plate, a lower bottom plate, and defoaming blades. The upper top plate and the lower bottom plate are fixed at the upper and lower ends of the eccentric column, respectively. The upper top plate and the lower bottom plate are rotatably fitted with the inner side of the detection tube. A central hole connected to the detection tube is opened on the eccentric column. The defoaming blades are evenly spaced along the circumference of the eccentric column on the outer side of the eccentric column. An exhaust channel communicating with the air outlet is opened on the inner side of the defoaming blades. The exhaust port of the exhaust channel is located at the outer end of the defoaming blade.

[0007] Furthermore, a second float is provided on the upper side of the defoaming device. The second float is slidably sleeved on the outside of the central tube. The second float has a cylindrical structure and the outer wall of the second float slides and seals with the inner wall of the detection tube. A ball bearing is rolled on the upper side of the top plate and can contact the lower end of the second float.

[0008] Furthermore, the lower end of the second float is provided with an air collection groove, the detection tube is provided with an air collection port, a partition is fixed in the central channel, the air collection port and the air outlet are located on the upper and lower sides of the partition, and a one-way air outlet valve is installed on the upper side of the air collection port in the central channel.

[0009] Furthermore, an elastic support device is installed on the inner side of the sealing plate, and the output end of the elastic support device abuts against the upper end of the second float.

[0010] Furthermore, a first gear is installed on the outer side of the upper end of the detection tube. The first gear and the second gear mesh. The second gear is keyed to the output shaft and can move along the axial direction of the output shaft. The output shaft is connected to the motor. A lifting device is installed on the sealing plate. The output end of the lifting device is connected to a support plate, which is used to support the first gear and the second gear.

[0011] Furthermore, the detection tube includes a detachably connected bottom tube and a through tube. The lower end face of the through tube has an annular groove located outside the return channel, and an electric heating device is installed inside the annular groove.

[0012] The beneficial effects of this invention are as follows: This invention discloses a toxin detection device for food and pharmaceuticals. The device can stir the added reagents to ensure the concentration of the sample, and the device can eliminate the bubbles generated after stirring, thereby improving the accuracy of the toxin detection results. Attached Figure Description

[0013] To make the objectives, technical solutions, and beneficial effects of this invention clearer, the following figures are provided for illustration: Figure 1 This is a schematic diagram of the structure of the device of the present invention; Figure 2 for Figure 1 Enlarged view of point A in the middle; Figure 3 for Figure 1 Enlarged view of point B in the middle; Figure 4 This is a schematic diagram of the defoaming device; Figure 5 This is a schematic diagram of the exhaust channel.

[0014] The following components are labeled in the attached diagram: support base 1, detection tube 2, sealing plate 3, central tube 4, stirring device 5, defoaming device 6, first float 7, central channel 8, air inlet 9, air outlet 10, liquid inlet 11, liquid outlet 12, transfer pump 13, defoaming net 14, eccentric column 15, upper top plate 16, lower bottom plate 17, defoaming blade 18, central hole 19, exhaust channel 20, second float 21, ball bearing 22, air collecting groove 23, air collecting port 24, one-way air outlet valve 25, elastic support device 26, first gear 27, second gear 28, output shaft 29, motor 30, lifting device 31, support plate 32, bottom tube 33, through pipe 34, annular groove 35, electric heating device 36, partition block 37. Detailed Implementation

[0015] like Figures 1-5 As shown, the present invention discloses a toxin detection device for food and medicine, including a support base 1 and a detection tube 2 installed on the support base 1. The support base 1 adopts an existing structure and is used to support the detection tube 2. The detection tube 2 is installed on the support base 1 to ensure that the device will not shake during use.

[0016] The detection tube 2 of this invention has an upward-facing opening and its axis is parallel to the vertical direction, which facilitates sampling and allows for stirring of the sample inside, preventing liquid overflow. A sealing plate 3 is installed at the opening of the detection tube 2, and a central tube 4 is coaxially rotatably mounted inside the detection tube 2. The lower end of the central tube 4 is closed, and the upper end of the central tube 4 passes through the sealing plate 3 and is connected to a rotation drive device. An agitator 5 and a defoaming device 6 are simultaneously connected to the outside of the central tube 4. The rotation drive device drives the central tube 4 to rotate, and the central tube 4 drives the agitator 5 and the defoaming device 6 to operate.

[0017] A first float 7 is slidably fitted on the outer side of the central tube 4. The first float 7 can float on the upper side of the liquid. The first float 7 is located between the stirring device 5 and the defoaming device 6. The first float 7 has a cylindrical structure and its outer side wall is slidably sealed with the inner side wall of the detection tube 2. A central channel 8 is formed in the center of the central tube 4. An air inlet 9 and an air outlet 10 are opened on the tube wall of the central tube 4. The air outlet 10 and the air inlet 9 are respectively arranged on the upper and lower sides of the first float 7. A liquid inlet 11 and a liquid outlet 12 are opened on the side wall of the detection tube 2. The liquid inlet 11 and the liquid outlet 12 are connected through a reflux channel. The liquid inlet 11 and the liquid outlet 12 are respectively arranged on the upper and lower sides of the first float 7.

[0018] The working principle and process of the device of the present invention are as follows: After the reagent is injected into the detection tube 2, the first float 7 and the second float 21 are loaded into the central tube 4, the stirring device 5, and the defoaming device 6. The rotation drive is then activated, and the central tube 4 drives the stirring device 5 to agitate the reagent, improving the uniformity of the endotoxins within the reagent. Simultaneously, when bubbles are present on the upper side of the liquid surface, they can enter the central channel 8 through the air inlet 9 and then enter the defoaming device 6 through the air outlet 10. After being defoamed by the defoaming device 6, the broken bubbles are returned to the reagent below through the reflux channel. This avoids the problem in traditional devices where excessive bubbles reduce the actual concentration of the analyte in the liquid phase, affecting the accuracy of quantitative analysis.

[0019] In this embodiment, a delivery pump 13 and a defoaming net 14 are installed in the central channel 8. The delivery pump 13 is used to provide power and can be electrically controlled. Different delivery speeds can be selected according to different reagents. During the delivery process, defoaming can be performed by the defoaming net 14. The delivery pump 13 is used to deliver the bubbles in the air inlet 9 to the air outlet 10. The defoaming net 14 is located below the delivery pump 13. The defoaming device 6 breaks the bubbles after rotating.

[0020] In this embodiment, the defoaming device 6 includes an eccentric column 15, an upper top plate 16, a lower bottom plate 17, and defoaming blades 18. The upper top plate 16 and the lower bottom plate 17 are respectively fixed to the upper and lower ends of the eccentric column 15. The upper top plate 16 and the lower bottom plate 17 are rotatably engaged with the inner side of the detection tube 2. A central hole 19 connected to the detection tube 2 is opened on the eccentric column 15. The defoaming blades 18 are evenly spaced along the circumference of the eccentric column 15 on the outer side of the eccentric column 15. An exhaust channel 20 communicating with the air outlet 10 is opened on the inner side of the defoaming blades 18. The exhaust port of the exhaust channel 20 is located at the outer end of the defoaming blades 18.

[0021] In this embodiment, a second float 21 is provided on the upper side of the defoaming device 6. The second float 21 is slidably sleeved on the outside of the central tube 4. The second float 21 has a cylindrical structure, and its outer wall is slidably sealed to the inner wall of the detection tube 2. A ball bearing 22 is rolled on the upper side of the top plate 16, and the ball bearing 22 can contact the lower end of the second float 21. When the reagent vibrates during stirring, the vibration can be transmitted to the first float 7, and the vibration is damped by the air cavity between the first float 7 and the second float 21, increasing the stability of the structure during use. The second float 21 can also suppress the reagent from overflowing, thus acting as a limiting element.

[0022] In this embodiment, the lower end of the second float 21 is provided with a gas collecting groove 23, the detection tube 2 is provided with a gas collecting port 24, a partition 37 is fixed in the central channel 8, the gas collecting port 24 and the gas outlet 10 are respectively arranged on the upper and lower sides of the partition 37, and a one-way gas outlet valve 25 is installed on the upper side of the gas collecting port 24 in the central channel 8 to facilitate the discharge of gas.

[0023] In this embodiment, an elastic support device 26 is installed on the inner side of the sealing plate 3. The output end of the elastic support device 26 abuts against the upper end of the second float 21, which can be used to buffer the amplitude of the float.

[0024] In this embodiment, a first gear 27 is installed on the outer side of the upper end of the detection tube 2, and the first gear 27 meshes with a second gear 28. The second gear 28 is keyed to the output shaft 29 and can move along the axial direction of the output shaft 29. The output shaft 29 is connected to a motor 30. A lifting device 31 is installed on the sealing plate 3, and a support plate 32 is connected to the output end of the lifting device 31. The support plate 32 is used to support the first gear 27 and the second gear 28. By designing the lifting device 31, the depth of the central tube 4 inside the detection tube 2 can be changed, so that the air inlet 9 is adapted to the height of the liquid level as much as possible, which facilitates air intake and exhaust.

[0025] In this embodiment, the detection tube 2 includes a detachably connected bottom tube 33 and a through tube 34. The lower end face of the through tube 34 is provided with an annular groove 35. The annular groove 35 is located outside the return channel. An electric heating device 36 is installed in the annular groove 35. The electric heating device 36 includes a heating wire, a power supply and a controller. The heating wire is installed in the annular groove 35 and the temperature is controlled by the controller. By adding the electric heating device 36, the activity of the air is increased, which helps the bubbles to burst.

Claims

1. A toxin detection device for food and pharmaceuticals, characterized in that: The device includes a support base and a detection tube mounted on the support base. The opening of the detection tube faces upward and its axis is parallel to the vertical direction. A sealing plate is installed at the opening of the detection tube. A central tube is coaxially and rotatably mounted on the inner side of the detection tube. The upper end of the central tube passes through the sealing plate and is connected to a rotation drive device. An agitator and a defoaming device are connected to the outer side of the central tube. A first float is slidably sleeved on the outer side of the central tube. The first float is located between the agitator and the defoaming device. The first float has a cylindrical structure and its outer wall is slidably sealed to the inner wall of the detection tube. A central channel is formed in the center of the central tube. An air inlet and an air outlet are opened on the wall of the central tube. The air outlet and the air inlet are located on the upper and lower sides of the first float, respectively. A liquid inlet and a liquid outlet are opened on the side wall of the detection tube. The liquid inlet and the liquid outlet are connected through a reflux channel. The liquid inlet and the liquid outlet are located on the upper and lower sides of the first float, respectively.

2. The toxin detection device in food and medicine according to claim 1, characterized in that: A delivery pump and a defoaming screen are installed in the central channel. The delivery pump is used to transport the air bubbles from the inlet to the outlet. The defoaming screen is located below the delivery pump. The defoaming device breaks up the air bubbles after rotating.

3. The toxin detection device in food and medicine according to claim 2, characterized in that: The defoaming device includes an eccentric column, an upper top plate, a lower bottom plate, and defoaming blades. The upper top plate and the lower bottom plate are fixed at the upper and lower ends of the eccentric column, respectively. The upper top plate and the lower bottom plate are rotatably fitted with the inner side of the detection tube. A central hole connected to the detection tube is opened on the eccentric column. The defoaming blades are evenly spaced along the circumference of the eccentric column on the outer side of the eccentric column. An exhaust channel communicating with the air outlet is opened on the inner side of the defoaming blades. The exhaust port of the exhaust channel is located at the outer end of the defoaming blade.

4. The toxin detection device in food and medicine according to claim 3, characterized in that: A second float is provided on the upper side of the defoaming device. The second float is slidably sleeved on the outside of the central tube. The second float has a cylindrical structure and the outer wall of the second float slides and seals with the inner wall of the detection tube. A ball bearing is rolled on the upper side of the top plate and can contact the lower end of the second float.

5. The toxin detection device in food and medicine according to claim 4, characterized in that: The lower end of the second float is provided with an air collection groove, the detection tube is provided with an air collection port, a partition is fixed in the central channel, the air collection port and the air outlet are located on the upper and lower sides of the partition, and a one-way air outlet valve is installed on the upper side of the air collection port in the central channel.

6. The toxin detection device in food and medicine according to claim 5, characterized in that: An elastic support device is installed on the inner side of the sealing plate, and the output end of the elastic support device abuts against the upper end of the second float.

7. The toxin detection device in food and medicine according to claim 1, characterized in that: A first gear is installed on the outer side of the upper end of the detection tube. The first gear and the second gear mesh. The second gear is keyed to the output shaft and can move along the axial direction of the output shaft. The output shaft is connected to the motor. A lifting device is installed on the sealing plate. The output end of the lifting device is connected to a support plate, which is used to support the first gear and the second gear.

8. A toxin detection device for food and drugs according to any one of claims 1-7, characterized in that: The detection tube includes a detachably connected bottom tube and a through tube. The lower end face of the through tube has an annular groove located outside the return channel. An electric heating device is installed inside the annular groove.

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