Water-oil double-layer permeation-promoting cosmetic composition and preparation method thereof

By combining isosorbide dicaprylate, dipropylene glycol, and glyceryl glucoside, a lipid microchannel and hydrogen bond network were constructed, which solved the problem of unstable penetration enhancement in water-oil dual-layer cosmetic systems. This achieved efficient and stable penetration of ingredients with different polarities without damaging the skin barrier.

CN122097178AActive Publication Date: 2026-05-29HUNAN YUJIA COSMETICS MFG CO LTD
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Patent Information

Application Number
CN202610578510.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-04-29
Publication Date
2026-05-29
Estimated Expiration
2046-04-29

AI Technical Summary

Technical Problem

In existing water-oil dual-layer cosmetic systems, the uneven distribution of traditional penetration enhancers leads to unstable effects. Single penetration enhancers have limited ability to enhance the penetration of ingredients with different polarities. High concentrations of penetration enhancers can easily cause skin irritation. There is a lack of broad-spectrum and efficient synergistic penetration enhancement solutions.

Method used

By employing a combination of isosorbide dicaprylate, dipropylene glycol, and glyceryl glucoside, this product achieves a synergistic enhancement of penetration efficiency through the construction of lipid microchannels, enhanced stratum corneum hydration, and activation of AQP3 aquaporin. This process forms a hydrogen bond network and a co-solubility mechanism, promoting the homogenization and synchronous penetration of active ingredients on the skin surface.

Benefits of technology

It achieves broad-spectrum penetration enhancement capabilities for active ingredients with different polarities, stable penetration effect, does not damage the integrity of the skin barrier, significantly improves penetration effect by 4.3-4.7 times, and is stably distributed in the oil and water phases.

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Abstract

The invention provides a water-oil double-layer permeation-promoting cosmetic composition and a preparation method thereof, and relates to the field of cosmetics. The water-oil double-layer permeation-promoting cosmetic composition is prepared from the following raw materials in percentage by mass: 5-30% of an oil phase and 70-95% of a water phase, the raw materials of the water phase comprise dipropylene glycol, glycosylglycerol and water; the raw materials of the oil phase comprise caprylic / capric triglyceride and isosorbide dicaprylate. The isosorbide dicaprylate in the water-oil double-layer permeation-enhancing cosmetic composition constructs a lipid microchannel, the dipropylene glycol enhances hydration of a cuticle, the glycosylglycerol activates AQP3 aquaporin, and the three channels synergistically improve the permeation efficiency without damaging the integrity of a skin barrier; the penetration enhancer has strong broad-spectrum penetration enhancing capacity on functional components with different polarities, has stable penetration enhancing effect, and can be stably distributed in an oil phase and a water phase.
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