A filtration device for separating radiolabeled substances
By designing a pressurization and stirring mechanism to work in tandem, the problems of raw material agglomeration and uneven stirring in traditional filtration devices are solved, achieving efficient separation of radiolabeled substances and improving filtration rate and separation purity.
Patent Information
- Application Number
- CN202610397001.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-03-30
- Publication Date
- 2026-05-29
AI Technical Summary
Traditional filtration devices are prone to clogging and uneven mixing due to raw material agglomeration when processing radiolabeled materials, which affects separation efficiency and purity.
A filtration device comprising a pressurizing mechanism, a stirring mechanism, and a driving mechanism was designed. By reciprocating the lifting and lowering of the pressurizing plate and intermittent air injection, combined with the circumferential stirring of multiple stirring rods, multi-zone stirring and uniform filtration of raw materials can be achieved.
It improves filtration rate and separation effect, reduces dead zones in stirring, enhances the uniformity of contact between raw materials and filter membrane, and improves separation purity and efficiency.
Smart Images

Figure CN122098202A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of marker processing technology, specifically to a filtration device for separating radioactive marker substances. Background Technology
[0002] Radiolabeled substances, as special functional materials, play an irreplaceable role in various fields such as medical diagnostics, biomedical research, and environmental monitoring. In medical diagnostics, radiolabeled drugs can be used for tumor imaging, cardiovascular disease detection, etc., helping doctors to accurately locate the position and extent of lesions. However, during the synthesis or preparation of radiolabeled substances, unreacted raw materials, byproducts, and other impurities are often present. The presence of these impurities can seriously affect the purity and effectiveness of the labeled substances. For example, in medical diagnostics, insufficient purity of radiolabeled drugs may lead to blurred imaging, interfering with doctors' diagnostic judgments, and even posing potential risks to patients' health due to the toxic side effects of impurities. In scientific research experiments, impurities can affect the accuracy of experimental data, leading to biased research conclusions. Therefore, efficient and precise separation and purification of radiolabeled substances is a key step in their practical application, and filtration, as one of the core methods of separation and purification, is widely used in the processing of radiolabeled substances.
[0003] However, traditional filtration devices face many problems in practical use. On the one hand, the raw material system of radiolabeled substances often exhibits agglomeration, especially when the raw material concentration is high or the viscosity is high. Agglomerated particles can clog the pores of the filter membrane, leading to a significant decrease in filtration rate and severely affecting separation efficiency. On the other hand, the stirring mechanism of traditional filtration devices mostly rotates in one direction, resulting in many dead zones and uneven contact between the raw material and the filter membrane. In some areas, the raw material cannot fully penetrate the filter membrane, thus affecting the separation purity. Therefore, it is necessary to develop a filtration device for the separation of radiolabeled substances. Summary of the Invention
[0004] The purpose of this section is to outline some aspects of the embodiments of the present invention and to briefly describe some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of this application, to avoid obscuring the purpose of this section, the abstract, and the title, and such simplifications or omissions should not be used to limit the scope of the invention.
[0005] To address the aforementioned technical problems, according to one aspect of the present invention, the present invention provides the following technical solution: A filtration device for separating radiolabeled substances includes a housing, a pressurizing mechanism, a stirring mechanism, and a driving mechanism; A grid frame is fixedly installed on the lower side of the inner cavity of the outer shell, and a filter membrane for filtering raw materials is fixedly covered on the upper surface of the grid frame. The pressurizing mechanism includes a pressurizing plate that is raised and lowered within the outer shell cavity and located above the filter membrane. When the pressurizing plate reciprocates, gas is intermittently injected between the pressurizing plate and the filter membrane, and the raw material is reciprocated and pressurized. The stirring mechanism is located between the filter membrane and the pressure plate and is used to stir the raw materials in multiple areas. It includes multiple stirring rods arranged in a circumferential rotation and multiple stirring blades fixed in a circumferential manner on each stirring rod. The drive mechanism is mounted on the outer casing and is used to drive the pressure plate to reciprocate up and down, and simultaneously drive the stirring rod to rotate and rise and fall.
[0006] As a preferred embodiment of the filtration device for separating radiolabeled substances according to the present invention, wherein: the outer shell is in the shape of a sealed "bucket", the pressure plate is in the shape of a "circular plate", and a sealing ring is fixedly provided on its outer side to fit against the inner wall of the outer shell; The top of the outer shell is fixedly provided with a feeding hopper that is wider at the top and narrower at the bottom in the shape of a funnel. The top of the feeding hopper is hinged with a sealing cover adapted to seal the feeding hopper. The sealing cover is provided with a handle and a lock. The lower end of the feeding hopper is fixedly provided with a first corrugated telescopic tube, and the lower end of the first corrugated telescopic tube is fixedly provided through the lower surface of the pressure plate. The bottom of the outer shell is shaped like a funnel, wider at the top and narrower at the bottom. A first discharge pipe, which connects to the inner cavity of the outer shell, is fixedly installed at the center of the bottom of the outer shell, and a valve is installed on the first discharge pipe. A second discharge pipe is fixedly installed on the side wall of the outer shell. One end of the second discharge pipe is connected to the pressure plate and the filter membrane. A valve is installed on the second discharge pipe.
[0007] As a preferred embodiment of the filtration device for separating radiolabeled substances according to the present invention, the pressurizing mechanism further includes an air storage cylinder fixed to the top of the outer shell by a bracket. A vent hole is provided at the center of the bottom of the inner cavity of the air storage cylinder. A vertical fixed pipe is fixedly installed at the bottom of the air storage cylinder. A one-way valve plate for controlling the opening and closing of the vent hole is hinged at the top of the inner cavity of the fixed pipe at the bottom of the air storage cylinder. An air supply bellows is fixedly installed on the side wall of the fixed pipe, below the one-way valve plate. The upper end of the air supply bellows communicates with the inner cavity of the fixed pipe, and the lower end is sealed and penetrates the bottom of the pressure plate and communicates with the pressure plate and the filter membrane. The bottom seal of the fixed tube passes through the top of the outer shell, and a vertical follower rack is provided through the bottom wall of its inner cavity for sliding movement. A "round plate" shaped push-pull plate is fixedly provided at the upper end of the follower rack, and a sealing ring that fits against the inner wall of the fixed tube is fixedly provided on the outer side of the push-pull plate. On the top wall of the inner cavity of the outer shell, there are support plates symmetrically fixed at the front and rear positions near the left side of the follower rack. A follower gear is rotatably arranged between the bottoms of the two support plates through a rotating shaft. On the top of the pressure plate, there is a vertical driving rack fixed near the left side of the follower gear. The right side of the follower gear meshes with the follower rack, and the left side of the follower gear meshes with the driving rack.
[0008] As a preferred scheme of a filtering device for separating radioactive labeled substances according to the present invention, when the one-way valve plate is turned downwards and the air vent hole is in an open state, the inner cavity of the air storage cylinder is connected to the space between the pressure plate and the filter membrane through an air delivery bellows. When the one-way valve plate is turned upwards and fits to block the air vent hole, the inner cavity of the air storage cylinder is disconnected from the space between the pressure plate and the filter membrane.
[0009] As a preferred scheme of a filtering device for separating radioactive labeled substances according to the present invention, a vertical self-locking threaded rod is screwed through the center of the top of the air storage cylinder. The lower end of the self-locking threaded rod is connected to a "round plate"-shaped lower pressure plate through a bearing. A sealing ring that fits with the inner side wall of the air storage cylinder is fixedly arranged on the outer side of the lower pressure plate. A knob is fixedly arranged at the upper end of the self-locking threaded rod. An inert gas that does not chemically react with the raw material is filled below the lower pressure plate in the inner cavity of the air storage cylinder. A barometer for monitoring the gas pressure and an air injection pipe for supplementing gas are arranged on the side wall of the air storage cylinder. A valve is arranged on the air injection pipe.
[0010] As a preferred scheme of a filtering device for separating radioactive labeled substances according to the present invention, the stirring mechanism further includes a mounting frame fixedly arranged around the bottom of the pressure plate. The mounting frame is in a "冂" shape and is arranged at equal angles with the pressure plate as the center. The ends where all the mounting frames靠拢 are jointly fixedly arranged with an "annular" mounting ring. The number and position of the mounting frames correspond to the number and position of the stirring rods. One end of the stirring rod is rotatably connected to the end of the mounting frame far from the mounting ring through a bearing, and the other end of the stirring rod is rotatably connected to the mounting ring through a bearing.
[0011] As a preferred scheme of a filtering device for separating radioactive labeled substances according to the present invention, the driving mechanism further includes a vertical hollow first hollow rod fixed on the top wall of the inner cavity of the outer shell. A vertical main rotating rod is rotatably penetrated through the inner side of the first hollow rod through a sealing bearing. A vertical reciprocating screw rod coaxial with itself is fixedly arranged at the lower end of the main rotating rod. Vertical guide rods are fixedly arranged around the main rotating rod and the reciprocating screw rod at equal intervals on the top wall of the inner cavity of the outer shell. A fixing frame is jointly fixedly arranged at the bottoms of all the guide rods. The lower end of the reciprocating screw rod is rotatably connected to the center of the top of the fixing frame through a bearing. A lifting plate is fixedly installed on the inner side of the mounting ring. The rod of the reciprocating screw moves through the center of the upper and lower walls of the lifting plate. The rod of the guide rod slides through the upper and lower walls of the lifting plate through a linear bearing. The rotating reciprocating screw drives the lifting plate to move up and down along the direction of the guide rod.
[0012] As a preferred embodiment of the filtration device for separating radiolabeled substances according to the present invention, wherein: the inner cavity top wall of the outer shell is fixedly arranged with vertical hollow second core rods at equal intervals around the first hollow core rod as the center; the upper and lower walls of the pressure plate are provided with through holes for the first hollow core rod, the second hollow core rod and the guide rod to pass through respectively; a sealing sleeve is provided on the inner side of each through hole; the number and position of the second hollow core rods correspond to the number and position of the stirring rods; a vertical secondary rotating rod is rotatably arranged through the inner side of each second hollow core rod via a sealed bearing; a vertical spline rod coaxial with itself is fixedly arranged at the lower end of each secondary rotating rod; and the lower end of each spline rod is rotatably connected to the top of the fixed frame via a bearing. The housing of the mounting ring has an annular sealed mounting cavity. Each splined rod has a matching splined sleeve slidably fitted on its outer side. All the splined sleeves rotate through the upper and lower surfaces of the sealed mounting cavity via bearings. The end of each stirring rod near the mounting ring is located inside the sealed mounting cavity via bearings. A follower bevel gear is fixedly installed at the end of the stirring rod located inside the sealed mounting cavity. A drive bevel gear is fixedly installed on the outer side of each splined sleeve located inside the sealed mounting cavity. The drive bevel gear meshes with its corresponding follower bevel gear.
[0013] As a preferred embodiment of the filtration device for separating radiolabeled substances according to the present invention, wherein: the top end of the main rotating rod extends rotatably out of the top of the outer shell and a main gear is fixedly provided on the outer side of the rod body; the top end of each of the auxiliary rotating rods extends rotatably out of the top of the outer shell and a secondary gear meshing with the main gear is fixedly provided on the outer side of the rod body; a follower bevel gear is fixedly provided at the top end of the main rotating rod; and a protective shell for housing the main gear, secondary gear and follower bevel gear is fixedly provided at the top of the outer shell. A servo motor is fixedly installed on the top of the housing. The output shaft of the servo motor rotates through the side wall of the protective housing via a sealed bearing. The output shaft of the servo motor is also fixedly equipped with a drive bevel gear that meshes with a follower bevel gear.
[0014] The beneficial effects of this invention are: 1. The pressure plate reciprocates to apply pressure to the raw material. At the same time, the push-pull plate is driven to move synchronously through the rack and pinion transmission. In conjunction with the one-way valve plate, intermittent gas injection is achieved. The gas can not only break up the raw material agglomerates, but also push the raw material through the filter membrane to improve the filtration rate. 2. The stirring mechanism adopts multiple surrounding stirring rods, each equipped with multiple stirring blades. The stirring rods are driven by a mechanism, and the combined motion of rotation and lifting can stir the raw material between the pressure plate and the filter membrane in multiple areas, reducing dead zones, improving the uniform contact of the raw material with the filter membrane, and enhancing the separation effect. Attached Figure Description
[0015] To more clearly illustrate the technical solutions of the embodiments of the present invention, the present invention will be described in detail below with reference to the accompanying drawings and detailed embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Wherein: Figure 1 This is a schematic diagram of the structure of the present invention; Figure 2 This is a structural schematic diagram of the internal components of the outer shell and gas storage cylinder, as well as the internal components of the protective shell of the present invention. Figure 3 This is a schematic diagram of the internal components of the gas storage cylinder of the present invention. Figure 4 This is a structural schematic diagram of the bottom component of the pressure plate of the present invention viewed from below. Figure 5 For the present invention Figure 4 A top-down structural diagram; Figure 6 This is a side-view structural diagram of the first and second hollow core rods and other components of the present invention. Figure 7 This is a schematic diagram of the internal components of the sealed mounting cavity of the present invention; Figure 8 This is a schematic diagram of the structure of the drive mechanism and other components of the present invention; Figure 9 This is a schematic diagram of the structure of the spline sleeve and the follower and drive bevel gears of the present invention.
[0016] In the diagram: Outer shell - 100; Filter membrane - 101; Feed hopper - 102; Sealing cap - 103; First corrugated telescopic tube - 104; First discharge pipe - 105; Second discharge pipe - 106; Pressurizing mechanism - 200; Pressurizing plate - 201; Support - 202; Air storage tank - 203; Fixed pipe - 205; One-way valve plate - 206; Air supply corrugated pipe - 207; Follower rack - 208; Push-pull plate - 209; Support plate - 210; Follower gear - 211; Drive rack - 212; Self-locking threaded rod - 213; Lower pressure plate - 214; Knob - 215; Barometer - 216; Air injection pipe - 217; Stirring mechanism - 300; Stirring Rod-301; Stirring blade-302; Mounting bracket-303; Mounting ring-304; Drive mechanism-400; First hollow rod-401; Main rotating rod-402; Reciprocating screw-403; Guide rod-404; Fixing bracket-405; Lifting plate-406; Second hollow rod-407; Secondary rotating rod-408; Spline rod-409; Sealed mounting cavity-410; Spline sleeve-411; Follower bevel gear-412; Drive bevel gear-413; Main gear-414; Secondary gear-415; Follower bevel gear-416; Protective shell-417; Servo motor-418; Drive bevel gear-419; Sealing sleeve-420. Detailed Implementation
[0017] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.
[0018] Many specific details are set forth in the following description in order to provide a full understanding of the invention. However, the invention may also be practiced in other ways different from those described herein, and those skilled in the art can make similar extensions without departing from the spirit of the invention. Therefore, the invention is not limited to the specific embodiments disclosed below.
[0019] Secondly, the present invention is described in detail with reference to the schematic diagrams. When detailing the embodiments of the present invention, for ease of explanation, the cross-sectional views illustrating the device structure may be partially enlarged, not according to the usual scale. Furthermore, the schematic diagrams are merely examples and should not limit the scope of protection of the present invention. In addition, actual fabrication should include three-dimensional spatial dimensions of length, width, and depth.
[0020] To make the objectives, technical solutions, and advantages of the present invention clearer, the embodiments of the present invention will be described in further detail below with reference to the accompanying drawings.
[0021] Please see Figures 1-9 The diagram shows a schematic representation of an embodiment of a filtration device for separating radiolabeled substances according to the present invention. Please refer to [link / reference]. Figures 1-9 This paper provides a detailed description of a filtration device for the separation of radiolabeled substances.
[0022] Example 1: A filtration device for separating radiolabeled substances, comprising a housing 100, a pressurizing mechanism 200, a stirring mechanism 300, and a driving mechanism 400, with the following specific structure: The outer shell 100 is in the shape of a sealed "bucket". The sealed design can effectively block radioactive materials and reduce the risk of leakage. A grid frame is fixedly installed on the lower side of the inner cavity of the outer shell 100. A filter membrane 101 for filtering raw materials is fixedly covered on the upper surface of the grid frame. The grid frame provides stable support for the filter membrane 101, preventing the filter membrane 101 from deforming or being damaged during the pressurization process and extending the service life of the filter membrane 101. A funnel-shaped feeding hopper 102, wider at the top and narrower at the bottom, is fixedly installed on the top of the outer casing 100. A sealing cover 103, adapted to seal the feeding hopper 102, is hinged to the top of the feeding hopper 102. The sealing cover 103 is equipped with a handle and a lock. The handle facilitates the opening and closing of the sealing cover 103, and the lock enhances the sealing effect of the feeding hopper 102, further improving the overall sealing performance of the device. A first corrugated telescopic tube 104 is fixedly installed at the outlet at the lower end of the feeding hopper 102. The lower end of the first corrugated telescopic tube 104 is fixedly inserted through the lower surface of the pressure plate 201. The first corrugated telescopic tube 104 can flexibly extend and retract with the lifting and lowering of the pressure plate 201, which is beneficial to the continuity of the feeding channel and does not damage the sealing environment of the pressurized area. The bottom of the outer shell 100 is funnel-shaped, wider at the top and narrower at the bottom. This structure facilitates the collection and discharge of filtered products, reducing product residue. A first discharge pipe 105, which connects to the inner cavity of the outer shell 100, is fixedly installed at the center of the bottom. A valve is installed on the first discharge pipe 105. A second discharge pipe 106 is fixedly installed on the side wall of the outer shell 100. One end of the second discharge pipe 106 is connected to the pressure plate 201 and the filter membrane 101. A valve is installed on the second discharge pipe 106. The two discharge pipes correspond to the discharge of filtered products and unfiltered raw materials, respectively, realizing classified collection and improving the convenience of operation.
[0023] In Example 2, based on Example 1, the pressurizing mechanism 200 includes a pressurizing plate 201 that is raised and lowered within the cavity of the outer shell 100 and located above the filter membrane 101. The pressurizing plate 201 is in the shape of a "circular plate", and a sealing ring is fixedly provided on its outer side to fit against the inner wall of the outer shell 100. The sealing ring can enhance the sealing performance between the pressurizing plate 201 and the outer shell 100 and improve the stability of the pressurizing effect. When the pressurizing plate 201 reciprocates, gas is intermittently injected between the pressurizing plate 201 and the filter membrane 101, and the raw material is reciprocated and pressurized. The reciprocating pressurization and intermittent gas injection work together to accelerate the filtration process of the raw material and help break up the agglomeration of the raw material through gas disturbance. The pressurizing mechanism 200 also includes an air storage cylinder 203 fixed to the top of the outer shell 100 by a bracket 202. A vent hole 204 is provided at the center of the bottom of the inner cavity of the air storage cylinder 203. A vertical fixed pipe 205 is fixedly installed at the bottom of the air storage cylinder 203. A one-way valve plate 206 for controlling the opening and closing of the vent hole 204 is hinged at the top of the inner cavity of the fixed pipe 205 at the bottom of the air storage cylinder 203. The one-way valve plate 206 can control the one-way flow of gas, avoid the backflow of raw materials or gas, and ensure the stability of the gas injection process. A gas delivery bellows 207 is fixedly installed on the side wall of the fixed pipe 205 below the one-way valve plate 206. The upper end of the gas delivery bellows 207 is connected to the inner cavity of the fixed pipe 205, and the lower end is sealed and penetrates the bottom of the pressurizing plate 201 and is connected to the pressurizing plate 201 and the filter membrane 101. The length of the gas delivery bellows 207 can be adjusted with the lifting and lowering of the pressurizing plate 201 to facilitate gas delivery. The bottom seal of the fixed tube 205 extends through the top of the outer shell 100, and a vertical follower rack 208 is slidably installed through its inner cavity bottom wall. A circular push-pull plate 209 is fixedly installed at the upper end of the follower rack 208. A sealing ring that fits against the inner wall of the fixed tube 205 is fixedly installed on the outer side of the push-pull plate 209. The sealing ring helps to ensure the sealing of the inner cavity of the fixed tube 205 during the movement of the push-pull plate 209. Supports are symmetrically fixed at the front and rear positions on the left side of the inner cavity top wall of the outer shell 100 near the follower rack 208. The bottom of the two support plates 210 is rotatably connected by a rotating shaft and a follower gear 211 is provided. A vertical drive rack 212 is fixedly provided on the top of the pressure plate 201 near the left side of the follower gear 211. The right side of the follower gear 211 meshes with the follower rack 208, and the left side of the follower gear 211 meshes with the drive rack 212. Through the meshing transmission of the rack and gear, the pressure plate 201 and the push-pull plate 209 can move synchronously without the need for additional power to drive the air injection action, thus improving the coordination of the mechanism. At the center of the top of the air storage cylinder 203, a vertical self-locking threaded rod 213 is screwed through. The lower end of the self-locking threaded rod 213 is connected with a "round plate"-shaped lower pressing plate 214 through a bearing. An outer side of the lower pressing plate 214 is fixedly provided with a sealing ring that fits the inner side wall of the air storage cylinder 203. The upper end of the self-locking threaded rod 213 is fixedly provided with a knob 215. By adjusting the lifting and lowering of the self-locking threaded rod 213 through the knob 215, the gas pressure inside the air storage cylinder 203 can be controlled to adapt to the filtration pressure requirements of different raw materials. Moreover, when the air pressure decreases, the air pressure inside the inner cavity of the air storage cylinder 203 can also be appropriately adjusted. An inert gas that does not chemically react with the raw materials is filled below the lower pressing plate 214 in the inner cavity of the air storage cylinder 203. The inert gas will not react with the radioactive labeling substance, avoiding affecting the purity of the raw materials and the separation effect; an air pressure gauge 216 for monitoring the gas pressure and an air injection pipe 217 for supplementing gas are provided on the side wall of the air storage cylinder 203. A valve is provided on the air injection pipe 217. The air pressure gauge 216 facilitates real-time understanding of the air pressure inside the air storage cylinder 203, and the air injection pipe 217 facilitates timely gas supplementation.
[0024] Embodiment 3. On the basis of Embodiment 1, a stirring mechanism 300 is arranged between the filter membrane 101 and the pressing plate 201 and is used for multi-region stirring of the raw materials, including multiple stirring rods 301 arranged in a circumferential rotation manner and multiple stirring blades 302 circumferentially fixed on the rod bodies of each stirring rod 301. The multiple stirring rods 301 and the multiple stirring blades 302 cooperate to expand the stirring coverage range and improve the stirring uniformity; The stirring mechanism 300 further includes an installation frame 303 circumferentially and fixedly arranged at the bottom of the pressing plate 201. The installation frame 303 is in a "冂" shape and is arranged at equal angles centered on the pressing plate 201. The converging ends of all the installation frames 303 are jointly and fixedly provided with an "annular" installation ring 304. The equally-angled distributed installation frames 303 are beneficial to the force balance of the stirring mechanism 300 and improve the operation stability; the number and position of the installation frames 303 are correspondingly set with the number and position of the stirring rods 301. One end of the stirring rod 301 is rotatably connected with the end of the installation frame 303 far from the installation ring 304 through a bearing, and the other end of the stirring rod 301 is rotatably connected with the installation ring 304 through a bearing. The bearing connection method reduces the rotation resistance of the stirring rod 301, reduces mechanical wear, and improves the service life of the mechanism.
[0025] Embodiment 4. On the basis of Embodiment 3, a driving mechanism 400 is arranged on the outer shell 100 and is used for driving the pressing plate 201 to reciprocate up and down, and synchronously driving the stirring rod 301 to rotate and lift, and a single power source realizes synchronous driving of multiple actions; The drive mechanism 400 also includes a vertical hollow first hollow rod 401 fixed to the top wall of the inner cavity of the outer shell 100. A vertical main rotating rod 402 is rotatably provided through the inner side of the first hollow rod 401 via a sealed bearing. The main rotating rod 402 is installed on the inner side of the first hollow rod 401 via a sealed bearing, so that when the main rotating rod 402 rotates, it will not affect the rotation of the pressure plate 201. A vertical reciprocating lead screw 403 coaxial with itself is fixedly installed at the lower end of the main rotating rod 402. Vertical guide rods 404 are fixedly installed in a ring around the main rotating rod 402 and the reciprocating lead screw 403 at equal intervals on the top wall of the inner cavity of the outer shell 100. A fixing frame 405 is fixedly installed at the bottom of all the guide rods 404. The lower end of the reciprocating lead screw 403 is rotatably connected to the top center of the fixing frame 405 through a bearing. The fixing frame 405 provides stable support for the reciprocating lead screw 403 and the guide rods 404, thereby improving the overall structural strength of the drive mechanism 400. A lifting plate 406 is fixedly installed on the inner side of the mounting ring 304. The rod body of the reciprocating screw 403 moves through the center of the upper and lower walls of the lifting plate 406. The rod body of the guide rod 404 slides through the upper and lower walls of the lifting plate 406 through a linear bearing. The rotating reciprocating screw 403 drives the lifting plate 406 to move up and down reciprocally along the direction of the guide rod 404. The guide rod 404 can limit the movement trajectory of the lifting plate 406, effectively preventing it from deviating, which is beneficial to completing the pressurization process. The inner cavity top wall of the outer shell 100 is fixedly provided with vertical hollow second hollow rods 407 at equal intervals around the first hollow rod 401. The number and position of the second hollow rods 407 correspond to the number and position of the stirring rods 301. A vertical auxiliary rotating rod 408 is rotatably provided through the inner side of each second hollow rod 407 via a sealed bearing. The auxiliary rotating rod 408 is installed on the inner side of the second hollow rod 407 via a sealed bearing, so that the rotation of the auxiliary rotating rod 408 will not affect the rotation of the pressure plate 201. A vertical spline rod 409 coaxial with itself is fixedly provided at the lower end of each auxiliary rotating rod 408. The lower end of each spline rod 409 is rotatably connected to the top of the fixing frame 405 via a bearing. The housing of the mounting ring 304 has an annular sealed mounting cavity 410 inside. Each spline rod 409 has a matching spline sleeve 411 slidably fitted on the outer side of its shaft. All the spline sleeves 411 pass through the upper and lower surfaces of the sealed mounting cavity 410 through the bearing. The spline connection can realize torque transmission and allow the spline sleeves 411 to slide along the axial direction of the spline rod 409, which can meet the combined motion requirements of the stirring rod 301 rotation and lifting. The end of each stirring rod 301 near the mounting ring 304 is located inside the sealed mounting cavity 410 through the bearing. A follower bevel gear 412 is fixedly installed at the end of the stirring rod 301 located inside the sealed mounting cavity 410. A drive bevel gear 413 is fixedly installed on the outer side of each spline sleeve 411 located inside the sealed mounting cavity 410. The drive bevel gear 413 meshes with the corresponding follower bevel gear 412. The bevel gear converts the vertical rotation into horizontal rotation, thereby driving the stirring rod 301 to rotate. The top end of the main rotating rod 402 extends out of the top of the outer casing 100, and a main gear 414 is fixedly installed on the outer side of the rod. The top end of each auxiliary rotating rod 408 extends out of the top of the outer casing 100, and an auxiliary gear 415 meshing with the main gear 414 is fixedly installed on the outer side of the rod. The main gear 414 meshes with multiple auxiliary gears 415 to achieve synchronous power distribution, which is beneficial to the consistent rotation speed of multiple stirring rods 301. A follower bevel gear 416 is fixedly installed at the top end of the main rotating rod 402. A protective shell 417 for housing the main gear 414, auxiliary gear 415 and follower bevel gear 416 is fixedly installed at the top of the outer casing 100. The protective shell 417 can prevent external dust and impurities from entering the gear transmission area, and at the same time prevent operators from contacting moving parts, thus improving the safety of the device. A servo motor 418 is fixedly installed on the top of the outer casing 100. The output shaft of the servo motor 418 rotates through the side wall of the protective casing 417 via a sealed bearing. The output shaft of the servo motor 418 is fixedly equipped with an active bevel gear 419 that meshes with the follower bevel gear 416. The servo motor 418 has high control precision and can realize the adjustment of speed and direction.
[0026] When using this filtration device to separate radiolabeled materials, first adjust the self-locking threaded rod 213 by knob 215 to move the lower pressure plate 214 inside the gas storage cylinder 203. With the help of the barometer 216, adjust the inert gas in the gas storage cylinder 203 to a suitable pressure. Then close the valve on the gas injection pipe 217. Open the sealing cover 103 and inject the radiolabeled material to be separated through the feeding hopper 102. The material enters the area between the pressure plate 201 and the filter membrane 101 through the first corrugated telescopic pipe 104. After the injection is completed, close the sealing cover 103 and lock the lock. The servo motor 418 is started, and its output shaft drives the active bevel gear 419 to rotate. The active bevel gear 419 meshes with the follower bevel gear 416, thereby driving the main rotating rod 402 to rotate. When the main rotating rod 402 rotates, it drives the reciprocating screw 403 at the lower end to rotate. The reciprocating screw 403 drives the lifting plate 406 to reciprocate along the guide rod 404. The lifting plate 406 drives the pressure plate 201 to reciprocate synchronously through the mounting ring 304 and the mounting bracket 303, thereby achieving reciprocating pressure on the raw material. On the other hand, the main rotating rod 402... Rod 402 drives the main gear 414 to rotate. The main gear 414 meshes with multiple secondary gears 415, which in turn drives the secondary rotating rod 408 to rotate. The secondary rotating rod 408 transmits torque to the spline sleeve 411 through the spline rod 409. The spline sleeve 411 drives the active bevel gear 413 to rotate. The active bevel gear 413 meshes with the follower bevel gear 412, which in turn drives the stirring rod 301 to rotate. At the same time, the lifting and lowering of the mounting ring 304 causes the spline sleeve 411 to slide axially along the spline rod 409, thereby achieving the synchronous lifting and lowering of the stirring rod 301 and achieving the effect of multi-zone mixing of raw materials. During the lifting and lowering of the pressure plate 201, the pressure plate 201 drives the active rack 212 to move synchronously. The active rack 212 meshes with the follower gear 211, driving the follower gear 211 to rotate. The follower gear 211 meshes with the follower rack 208, driving the follower rack 212 and the push-pull plate 209 to reciprocate up and down within the fixed tube 205. When the push-pull plate 209 descends, the air pressure in the space above the push-pull plate 209 in the fixed tube 205 decreases, the one-way valve plate 206 flips down, the vent 204 opens, and the inert gas in the air storage cylinder 203 enters the fixed tube 205, and then is injected into the raw material area through the air supply bellows 207. When the push-pull plate 209 rises, the air pressure in the fixed tube 205 increases, the one-way valve plate 206 flips up to block the vent 204, and the air injection stops, realizing the synchronous coordination of intermittent air injection, pressurization, and stirring. After filtration is completed, the servo motor 418 is turned off, the valve on the first discharge pipe 105 is opened, and the filtered product is collected. If unfiltered raw materials need to be discharged, the valve on the second discharge pipe 106 can be opened for discharge. The coordinated work of multiple mechanisms throughout the process improves filtration efficiency and separation effect.
[0027] Although the present invention has been described above with reference to embodiments, various modifications can be made and components can be replaced with equivalents without departing from the scope of the invention. In particular, as long as there is no structural conflict, the features in the disclosed embodiments can be combined with each other in any manner. The lack of an exhaustive description of these combinations in this specification is merely for the sake of brevity and resource conservation. Therefore, the present invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.
Claims
1. A filtration device for separating radiolabeled substances, comprising a housing (100), a pressurizing mechanism (200), a stirring mechanism (300), and a driving mechanism (400), characterized in that: A grid frame is fixedly provided on the lower side of the inner cavity of the outer shell (100), and a filter membrane (101) for filtering raw materials is fixedly covered on the upper surface of the grid frame. The pressurizing mechanism (200) includes a pressurizing plate (201) that is raised and lowered in the inner cavity of the outer shell (100) and located above the filter membrane (101). When the pressurizing plate (201) is raised and lowered, gas is injected intermittently between the pressurizing plate (201) and the filter membrane (101) to reciprocate and apply pressure to the raw material. The stirring mechanism (300) is disposed between the filter membrane (101) and the pressure plate (201) for multi-zone stirring of the raw materials. It includes multiple stirring rods (301) arranged in a circumferential rotation, and multiple stirring blades (302) fixed in a circumferential manner on the rod body of each stirring rod (301). The drive mechanism (400) is mounted on the housing (100) and is used to drive the pressure plate (201) to reciprocate up and down, and simultaneously drive the stirring rod (301) to rotate and rise and fall.
2. The filtration device for separating radiolabeled substances according to claim 1, characterized in that: The outer shell (100) is in the shape of a sealed "bucket", the pressure plate (201) is in the shape of a "circular plate", and a sealing ring is fixedly provided on its outer side to fit against the inner wall of the outer shell (100); The top of the outer shell (100) is fixedly provided with a feeding hopper (102) that is wider at the top and narrower at the bottom and is shaped like a funnel. The top of the feeding hopper (102) is hinged to a sealing cover (103) that is adapted to seal the feeding hopper (102). The sealing cover (103) is provided with a handle and a lock. The lower end of the feeding hopper (102) is fixedly provided with a first corrugated telescopic tube (104). The lower end of the first corrugated telescopic tube (104) is fixedly inserted through the lower surface of the pressure plate (201). The bottom of the outer shell (100) is funnel-shaped with a wider top and a narrower bottom. A first discharge pipe (105) is fixedly provided at the center of the bottom of the outer shell (100) and connects to its own inner cavity. A valve is provided on the first discharge pipe (105). The outer shell (100) is fixedly provided with a second discharge pipe (106) on its side wall. One end of the second discharge pipe (106) is connected to the pressure plate (201) and the filter membrane (101). A valve is provided on the second discharge pipe (106).
3. A filtration device for separating radiolabeled substances according to claim 1, characterized in that: The pressurizing mechanism (200) also includes an air storage cylinder (203) fixed to the top of the outer shell (100) by a bracket (202). A vent hole (204) is provided at the center of the bottom of the inner cavity of the air storage cylinder (203). A vertical fixed pipe (205) is fixedly provided at the bottom of the air storage cylinder (203). A one-way valve plate (206) for controlling the opening and closing of the vent hole (204) is hinged at the top of the inner cavity of the fixed pipe (205) at the bottom of the air storage cylinder (203). An air supply bellows (207) is fixedly provided on the side wall of the fixed pipe (205) below the one-way valve plate (206). The upper end of the air supply bellows (207) is connected to the inner cavity of the fixed pipe (205), and the lower end is sealed and penetrates the bottom of the pressurizing plate (201) and is connected to the pressurizing plate (201) and the filter membrane (101). The bottom seal of the fixed tube (205) passes through the top of the outer shell (100), and a vertical follower rack (208) is provided through the bottom wall of its inner cavity. A "round plate" shaped push-pull plate (209) is fixedly provided at the upper end of the follower rack (208), and a sealing ring that fits against the inner wall of the fixed tube (205) is fixedly provided on the outer side of the push-pull plate (209). The inner cavity top wall of the outer shell (100) is symmetrically fixed with support plates (210) at the front and rear positions of the left side of the follower rack (208). A follower gear (211) is rotatably arranged between the bottoms of the two support plates (210) through a rotating shaft. A vertical drive rack (212) is fixedly arranged at the top of the pressure plate (201) at the left side of the follower gear (211). The right side of the follower gear (211) meshes with the follower rack (208), and the left side of the follower gear (211) meshes with the drive rack (212).
4. A filtration device for separating radiolabeled substances according to claim 3, characterized in that: When the one-way valve plate (206) is flipped down and the vent (204) is in the open state, the inner cavity of the air storage cylinder (203) is connected to the pressure plate (201) and the filter membrane (101) through the air supply bellows (207); When the one-way valve plate (206) flips upward and fits to block the vent (204), the inner cavity of the air storage cylinder (203) is disconnected from the pressure plate (201) and the filter membrane (101).
5. A filtration device for separating radiolabeled substances according to claim 3, characterized in that: A vertical self-locking threaded rod (213) is threaded through the top center of the gas storage cylinder (203). The lower end of the self-locking threaded rod (213) is connected to a "circular plate" shaped lower pressure plate (214) via a bearing. A sealing ring that fits against the inner wall of the gas storage cylinder (203) is fixedly installed on the outer side of the lower pressure plate (214). A knob (215) is fixedly installed on the upper end of the self-locking threaded rod (213). The inner cavity of the gas storage cylinder (203) located below the lower pressure plate (214) is filled with an inert gas that does not chemically react with the raw materials. A barometer (216) for monitoring gas pressure and an injection pipe (217) for replenishing gas are installed on the side wall of the gas storage cylinder (203). A valve is installed on the injection pipe (217).
6. A filtration device for separating radiolabeled substances according to claim 1, characterized in that: The stirring mechanism (300) further includes a mounting frame (303) fixedly arranged in a surrounding manner at the bottom of the pressure plate (201). The mounting frame (303) is in an "L" shape and is arranged at equal angles centered on the pressure plate (201). The ends where all the mounting frames (303) come closer together are jointly fixedly provided with an "annular" mounting ring (304). The number and positions of the mounting frames (303) are correspondingly arranged with the number and positions of the stirring rods (301). One end of the stirring rod (301) is rotatably connected to the end of the mounting frame (303) far from the mounting ring (304) through a bearing, and the other end of the stirring rod (301) is rotatably connected to the mounting ring (304) through a bearing.
7. A filtration device for separating radiolabeled substances according to claim 6, characterized in that: The driving mechanism (400) further includes a vertical hollow first hollow rod (401) fixed to the top wall of the inner cavity of the housing (100). A vertical main rotating rod (402) is rotatably penetrated through the inside of the first hollow rod (401) by a sealed bearing. A vertical reciprocating screw rod (403) coaxial with itself is fixedly arranged at the lower end of the main rotating rod (402). Vertical guide rods (404) are fixedly arranged in a surrounding manner at equal intervals centered on the main rotating rod (402) and the reciprocating screw rod (403) on the top wall of the inner cavity of the housing (100). The bottoms of all the guide rods (404) are jointly fixedly provided with a fixing frame (405). The lower end of the reciprocating screw rod (403) is rotatably connected to the center of the top of the fixing frame (405) through a bearing; A lifting plate (406) is fixedly arranged inside the mounting ring (304). The rod body of the reciprocating screw rod (403) movably penetrates through the centers of the upper and lower walls of the lifting plate (406). The rod bodies of the guide rods (404) slide through the upper and lower walls of the lifting plate (406) through linear bearings. The rotating reciprocating screw rod (403) drives the lifting plate (406) to reciprocate up and down along the rod body direction of the guide rod (404).
8. A filtration device for separating radiolabeled substances according to claim 7, characterized in that: Vertical hollow second hollow rods (407) are fixedly arranged in a surrounding manner at equal intervals centered on the first hollow rod (401) on the top wall of the inner cavity of the housing (100). Through holes for the first hollow rod (401), the second hollow rods (407) and the guide rods (404) to penetrate respectively are formed in the upper and lower walls of the pressure plate (201). A sealing sleeve (420) is arranged inside each through hole. The number and positions of the second hollow rods (407) are correspondingly arranged with the number and positions of the stirring rods (301). A vertical sub-rotating rod (408) is rotatably penetrated through the inside of each second hollow rod (407) by a sealed bearing. A vertical spline rod (409) coaxial with itself is fixedly arranged at the lower end of each sub-rotating rod (408). The lower end of each spline rod (409) is rotatably connected to the top of the fixing frame (405) through a bearing; The housing of the mounting ring (304) has an annular sealing mounting cavity (410) inside. Each spline rod (409) has a matching spline sleeve (411) slidably fitted on the outer side of its shaft. All the spline sleeves (411) rotate through the upper and lower surfaces of the sealing mounting cavity (410) via bearings. One end of each stirring rod (301) near the mounting ring (304) rotates within the sealing mounting cavity (410) via bearings. A follower bevel gear (412) is fixedly installed at one end of the stirring rod (301) within the sealing mounting cavity (410). An active bevel gear (413) is fixedly installed on the outer side of each spline sleeve (411) within the sealing mounting cavity (410). The active bevel gear (413) meshes with its corresponding follower bevel gear (412).
9. A filtration device for separating radiolabeled substances according to claim 8, characterized in that: The top end of the main rotating rod (402) extends out of the top of the outer shell (100) and a main gear (414) is fixedly installed on the outside of the rod. The top end of each of the auxiliary rotating rods (408) extends out of the top of the outer shell (100) and a secondary gear (415) meshing with the main gear (414) is fixedly installed on the outside of the rod. A follower bevel gear (416) is fixedly installed at the top end of the main rotating rod (402). A protective shell (417) for housing the main gear (414), secondary gear (415) and follower bevel gear (416) is fixedly installed at the top of the outer shell (100). A servo motor (418) is fixedly installed on the top of the outer shell (100). The output shaft of the servo motor (418) rotates through the side wall of the protective shell (417) via a sealed bearing. The output shaft of the servo motor (418) is fixedly equipped with an active bevel gear (419) that meshes with the follower bevel gear (416).
