A method for purifying and preparing safflower red pigment components
CN122103072APending Publication Date: 2026-05-29DALIAN INSTITUTE OF CHEMICAL PHYSICS CHINESE ACADEMY OF SCIENCES
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Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- DALIAN INSTITUTE OF CHEMICAL PHYSICS CHINESE ACADEMY OF SCIENCES
- Filing Date
- 2024-11-28
- Publication Date
- 2026-05-29
AI Technical Summary
Technical Problem
Safflower red pigment has a complex composition and low content of active ingredients. Existing purification techniques have poor reproducibility and limited purity, making it difficult to achieve efficient quality control and good stability in purification.
Method used
A gradient extraction method of ethanol-water-50% ethanol-water combined with C18 packing material was used for purification. Impurities were removed through multi-step solvent selection and chromatographic separation to obtain high-purity red pigment.
Benefits of technology
The preparation of high-purity red pigment has been achieved, with high extraction and recovery rate, good stability, simple and controllable operation, strong repeatability, and suitability for automated production.
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Figure CN122103072A_ABST
Abstract
The application provides a method for purifying safflower red pigment components. The molecular weight of the red pigment is 583. The medicinal material is extracted twice with ethanol to remove weak polar components, then extracted three times with water to remove strong polar components, and finally the red pigment is extracted with 50% ethanol water, compared with direct extraction with 50% ethanol water, the recovery rate of the red pigment is 90%, most of the impurities can be removed, and the red pigment component with high purity is obtained, and the method can be used as the extraction method of the safflower red pigment. Further, the red pigment with high purity is obtained through C18YE purification. The scheme is simple, and no acid or alkali is used in the purification process, which is beneficial to the stability of the sample.
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