A biological reagent sampling machine

Abstract

The present application relates to the field of biological reagent sampling equipment, and particularly relates to a biological reagent sampling machine, which comprises a biological reagent storage and access integrated machine, the integrated machine is composed of a reagent storage part, an automatic sampling bin and an agitation control part, a multidirectional sampling equipment is arranged at the automatic sampling bin; a push-pull limiting rod of the reagent storage part drives a biological reagent storage container to move and transfer, the agitation control part drives the container to rotate and prevent stratification through a driving gear, a driven gear and a plug-in linkage structure, and the multidirectional sampling equipment realizes multipoint sampling by means of a longitudinal and transverse movement structure; the biological reagent sampling machine can avoid stratification of reagents, improve sampling accuracy and representativeness, optimize reagent storage safety, reduce pollution risk, improve sampling operation efficiency and meet the sampling demand of multiple batches of reagents.

Description

Technical Field

[0001] This invention relates to the field of biological reagent sampling equipment, specifically a biological reagent sampling machine. Background Technology

[0002] In various fields such as biological experiments, pharmaceutical research and development, and clinical testing, biological reagent sampling is a crucial preliminary step for subsequent analysis and testing. Different biological reagents exhibit significant differences in properties, and some suspensions are prone to stratification, placing stringent requirements on the uniformity and accuracy of sampling. To meet the testing needs of multiple batches and types of reagents, relevant sampling equipment must integrate reagent storage and sampling functions. Operators must extract reagents from storage containers for subsequent experiments or analysis. This process requires not only ensuring the safety and stability of reagent storage but also guaranteeing the convenience of sampling operations and the reliability of sampling results. Therefore, biological reagent sampling machines with reasonable storage structures and precise sampling capabilities have become essential equipment in these fields.

[0003] Existing biological reagent sampling machines mostly use fixed reagent storage containers, and the sampling operation is performed directly at the location of the storage container. For biological reagents that are prone to separation, it is impossible to fully mix them before sampling, which can easily lead to deviations in sampling concentration, affecting the accuracy of subsequent test results. Furthermore, it can easily contaminate other unsampled reagents, which is not conducive to the long-term safe storage of reagents. Therefore, in view of the above situation, there is an urgent need to develop a biological reagent sampling machine to overcome the shortcomings in current practical applications. Summary of the Invention

[0004] The purpose of this invention is to provide a biological reagent sampling machine to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, the present invention provides the following technical solution:

[0006] A biological reagent sampling machine includes a biological reagent storage and retrieval integrated machine, which consists of a reagent storage unit, an automatic sampling chamber, and a stirring control unit, wherein the automatic sampling chamber is located between the reagent storage unit and the stirring control unit;

[0007] The integrated biological reagent storage and retrieval machine is also equipped with a multi-directional sampling device, which is located in the automatic sampling chamber and is used to extract reagents from different locations within the reagent storage section.

[0008] The reagent storage section is fitted with a push-pull limiting rod, and a biological reagent storage container is fixedly installed on the push-pull limiting rod; when the reagent is in storage state, the biological reagent storage container is located inside the reagent storage section;

[0009] When the reagent is being sampled, an external force pushes the push-pull limit rod and moves the biological reagent storage container into the automatic sampling chamber. At this time, the stirring control unit drives the biological reagent storage container to rotate in the automatic sampling chamber according to the reagent type, so as to avoid the reagent from being separated into layers in the biological reagent storage container and affecting the accuracy of sampling.

[0010] As a further aspect of the present invention: the multi-directional sampling device includes:

[0011] The slide rail is located inside the automatic sampling chamber, and a lifting sliding bracket is slidably installed on the slide rail, and the lifting sliding bracket is provided with a second sliding groove.

[0012] A sampling lateral moving device, wherein the sampling lateral moving device is mounted on the lifting sliding bracket;

[0013] And a sampling device, one end of which passes through the second slide and is fixedly connected to the sampling transverse mobile device, and the other end of which is fixedly installed with a sampling pressure head.

[0014] As a further aspect of the present invention: the multi-directional sampling device further includes:

[0015] Slide 1 and slide 3 are respectively opened on both sides of the integrated biological reagent storage and retrieval machine, and are both connected to the automatic sampling chamber;

[0016] A sliding support member, one end of which is fixedly connected to the lifting sliding bracket, and the other end of which is inserted into the slide groove three and slidably connected to the slide groove three.

[0017] And a sampling vertical mobile device, which is fixedly installed on the biological reagent storage and retrieval integrated machine, and the sampling vertical mobile device is connected to the lifting sliding bracket through a connecting slide column;

[0018] The connecting slide column passes through the first slide groove and is slidably connected to the first slide groove.

[0019] As a further aspect of the present invention: the sampling longitudinal moving device and the sampling transverse moving device have the same structure, both consisting of a motor, a screw and a threaded sleeve;

[0020] The threaded sleeve is fitted onto the screw. The motor drives the screw to rotate, thereby moving the threaded sleeve. The two threaded sleeves respectively drive the lifting sliding bracket and the sampling device to move.

[0021] As a further aspect of the present invention, it also includes: an information display block, which is fixedly installed at the end of the push-pull limiting rod and is used to display the reagent information of the corresponding biological reagent storage container;

[0022] And an opening and closing control mounting base, which is fixedly mounted on the push-pull limit rod and connected to the inlet of the biological reagent storage container, for controlling the opening and closing of the inlet of the biological reagent storage container.

[0023] As a further aspect of the present invention: the reagent storage unit includes:

[0024] The storage compartments are multiple, and the multiple storage compartments are evenly distributed on the integrated biological reagent storage and retrieval machine;

[0025] The storage compartment has a sliding cavity at its top, and the push-pull limiting rod is inserted into the sliding cavity and slidably connected to the sliding cavity.

[0026] And a guide section, which is connected to the storage compartment and the biological reagent storage container, respectively.

[0027] As a further aspect of the present invention: the guide portion includes a limiting guide portion and a limiting guide groove, wherein the limiting guide portion is fixedly installed at the bottom end of the biological reagent storage container;

[0028] The limiting guide groove is located at the bottom end of the storage compartment, and the limiting guide part is slidably connected to the limiting guide groove.

[0029] As a further aspect of the present invention: the stirring control unit includes:

[0030] A control motor is fixedly installed on the integrated biological reagent storage and retrieval machine, and a drive gear is fixedly installed at the output end of the control motor. The drive gear is located inside the automatic sampling chamber.

[0031] Driven gears, there are multiple driven gears, the multiple driven gears are evenly distributed on the biological reagent storage and retrieval integrated machine, and all are located in the automatic sampling chamber;

[0032] The multiple driven gears are respectively installed opposite to the multiple push-pull limiting rods, and the multiple driven gears are connected to the drive gear through a toothed belt;

[0033] And a plug-in linkage structure, which is connected to the push-pull limiting rod, the driven gear and the biological reagent storage container respectively.

[0034] As a further embodiment of the present invention: the plug-in linkage structure includes a cross-shaped slot, a U-shaped frame, and a cross-shaped insert plate;

[0035] The number of cross slots is multiple, and the multiple cross slots are respectively opened on the end face of multiple driven gears;

[0036] The two ends of the U-shaped frame are fixedly connected to the push-pull limiting rod and the biological reagent storage container, respectively, and a cross insert plate is also fixedly installed on the U-shaped frame. The cross insert plate and the cross slot can be detachably connected.

[0037] When the biological reagent storage container arrives at the sampling station, the cross-shaped insert is inserted into the cross-shaped slot; when the biological reagent storage container arrives at the reagent storage section, the cross-shaped insert separates from the cross-shaped slot.

[0038] As a further aspect of the present invention: the stirring control unit further includes a control panel, which is fixedly installed on the biological reagent storage and retrieval integrated machine and electrically connected to the control motor, for controlling the rotation speed and rotation time of the multiple driven gears driven by the control motor according to the reagent type.

[0039] Compared with the prior art, the beneficial effects of the present invention are:

[0040] 1. The stirring control unit can control the motor to drive the driven gear to rotate according to the reagent type, thereby driving the biological reagent storage container to rotate in the automatic sampling chamber, avoiding reagent stratification, ensuring uniform sampling concentration, and improving sampling accuracy.

[0041] 2. The multi-directional sampling device uses the screw drive structure of the longitudinal and lateral sampling moving devices to drive the sampling head to move precisely, so as to achieve multi-point sampling at different depths and lateral positions in the reagent storage container, thereby improving the representativeness of the samples.

[0042] 3. The reagent storage section is equipped with multiple evenly distributed storage compartments, which can store a variety of biological reagents at the same time to meet the needs of multiple batch sampling; the closed storage compartments, together with the guiding structure of the limiting guide part and the limiting guide groove, reduce the risk of reagents being contaminated by the outside world and damaged by collision.

[0043] 4. The plug-in linkage structure enables the driven gear and the biological reagent storage container to quickly engage and disengage through the detachable connection of the cross plate and the cross slot. This ensures both the mixing effect and facilitates the return of the container to the storage chamber after sampling, thus improving operational flexibility.

[0044] 5. The information display box can display information such as reagent name, concentration and expiration date in real time, without the need to check the ledger separately; the opening and closing control mounting base realizes the automatic opening and closing of the biological reagent storage container inlet, reducing the risk of contamination caused by manual operation, reducing the risk of reagent contamination and improving efficiency. Attached Figure Description

[0045] Figure 1 This is a three-dimensional structural diagram of the biological reagent sampling machine in an embodiment of the present invention.

[0046] Figure 2 This is a three-dimensional structural diagram of the installation position of the control panel in an embodiment of the present invention.

[0047] Figure 3 This is a three-dimensional structural diagram of the distribution of push-pull limiting rods in an embodiment of the present invention.

[0048] Figure 4 This is a three-dimensional structural diagram of the automatic sampling chamber in an embodiment of the present invention.

[0049] Figure 5 This is a three-dimensional structural diagram of the storage compartment distribution in an embodiment of the present invention.

[0050] Figure 6 This is a three-dimensional structural diagram showing the distribution of the sliding cavity and the limiting guide groove in an embodiment of the present invention.

[0051] Figure 7 This is a front view schematic diagram of the driven gear and toothed belt connection state in an embodiment of the present invention.

[0052] Figure 8 This is a three-dimensional structural diagram of the driven gear distribution in an embodiment of the present invention.

[0053] Figure 9 This is an enlarged structural schematic diagram of the lifting and sliding bracket in an embodiment of the present invention.

[0054] Figure 10 This is a three-dimensional structural diagram of the sampling horizontal mobile device in an embodiment of the present invention.

[0055] Figure 11 This is a three-dimensional structural diagram of the cross-shaped insert plate in an embodiment of the present invention.

[0056] Figure 12 This is an enlarged structural schematic diagram of the push-pull limiting rod in an embodiment of the present invention.

[0057] Figure 13 This is a three-dimensional structural diagram of the U-shaped frame in an embodiment of the present invention.

[0058] In the diagram: 1-Integrated biological reagent storage and retrieval machine, 2-Control panel, 3-Slide 1, 4-Sampling longitudinal movement device, 5-Control motor, 6-Lifting sliding bracket, 7-Slide 2, 8-Sampling lateral movement device, 9-Push-pull limit rod, 10-Sliding support, 11-Slide 3, 12-Automatic sampling chamber, 13-Information display block, 14-Sampling device, 15-Slide rail, 16-Storage chamber, 17-Sliding cavity, 18-Drive gear, 19-Driven gear, 20-Cross slot, 21-Toothed belt, 22-Sampling head, 23-Connecting slide column, 24-Opening and closing control mounting base, 25-Biological reagent storage container, 26-U-shaped frame, 27-Cross insert plate, 28-Limiting guide, 29-Limiting guide groove. Detailed Implementation

[0059] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0060] The specific implementation of the present invention will be described in detail below with reference to specific embodiments.

[0061] Please see Figures 1-13 The present invention provides a biological reagent sampling machine, which includes a biological reagent storage and retrieval integrated machine 1. The biological reagent storage and retrieval integrated machine 1 is composed of a reagent storage unit, an automatic sampling chamber 12 and a stirring control unit. The automatic sampling chamber 12 is located between the reagent storage unit and the stirring control unit.

[0062] The biological reagent storage and retrieval integrated machine 1 is also equipped with a multi-directional sampling device 14, which is located in the automatic sampling chamber 12 and is used to extract reagents from different locations in the reagent storage section.

[0063] The reagent storage section is fitted with a push-pull limiting rod 9, and a biological reagent storage container 25 is fixedly installed on the push-pull limiting rod 9; when the reagent is in storage state, the biological reagent storage container 25 is located inside the reagent storage section;

[0064] When the reagent is being sampled, an external force pushes the push-pull limit rod 9 and moves the biological reagent storage container 25 into the automatic sampling chamber 12. At this time, the stirring control unit drives the biological reagent storage container 25 to rotate in the automatic sampling chamber 12 according to the reagent type, so as to avoid the reagent from being separated into layers in the biological reagent storage container 25 and affecting the accuracy of sampling.

[0065] When biological reagent sampling is required, the operator pushes the push-pull limit lever 9, which is equipped with the information display block 13 (or existing mechanical equipment, such as a hydraulic system, can be used for pushing and pulling, which will not be elaborated here), so that the biological reagent storage container 25, which is originally stored in the reagent storage compartment 16, slides along the limit guide structure into the automatic sampling compartment 12. Compared with the existing technology of directly sampling from a fixed storage container, this invention avoids interference with other stored reagents during the sampling process by transferring the biological reagent storage container 25 to a dedicated sampling compartment. In addition to contaminated reagents, the stirring control unit drives the biological reagent storage container 25 to rotate at a preset speed in the automatic sampling chamber 12 according to the reagent type information transmitted by the information display block 13. For easily stratified suspension-type biological reagents, this rotation action can make the reagent components fully mixed, thereby avoiding sampling concentration deviation caused by reagent stratification and ensuring the accuracy of subsequent sampling and testing results. After sampling is completed, the biological reagent storage container 25 can be sent back to the reagent storage section for sealing by pulling the push-pull limit rod 9 in the opposite direction, which effectively improves the convenience of sampling operation and the safety of reagent storage.

[0066] In one embodiment of the present invention, please refer to Figures 1-13 The multi-directional sampling device 14 includes:

[0067] The slide rail 15 is located inside the automatic sampling chamber 12, and a lifting sliding bracket 6 is slidably installed on the slide rail 15. The lifting sliding bracket 6 is provided with a second sliding groove 7.

[0068] A sampling lateral moving device 8 is mounted on the lifting sliding bracket 6;

[0069] And sampling device 14, one end of which passes through the slide groove 7 and is fixedly connected to the sampling horizontal moving device 8, and the other end of the sampling device 14 is fixedly installed with a sampling pressure head 22.

[0070] The multi-directional sampling device 14 further includes:

[0071] Slide 3 and slide 11 are respectively opened on both sides of the integrated biological reagent storage and retrieval machine 1, and are both connected to the automatic sampling chamber 12.

[0072] A sliding support 10, one end of which is fixedly connected to the lifting sliding bracket 6, and the other end of which is inserted into the sliding groove 11 and slidably connected to the sliding groove 11.

[0073] And a sampling vertical moving device 4, which is fixedly installed on the biological reagent storage and retrieval integrated machine 1, and the sampling vertical moving device 4 is connected to the lifting sliding bracket 6 through a connecting sliding column 23;

[0074] The connecting slide post 23 passes through the slide groove 3 and is slidably connected to the slide groove 3.

[0075] The sampling longitudinal moving device 4 and the sampling transverse moving device 8 have the same structure, both consisting of a motor, a screw and a threaded sleeve;

[0076] The threaded sleeve is fitted onto the screw. The motor drives the screw to rotate, thereby moving the threaded sleeve. The two threaded sleeves respectively drive the lifting sliding bracket 6 and the sampling device 14 to move.

[0077] Both the longitudinal sampling device 4 and the transverse sampling device 8 adopt a screw drive structure with a motor-driven screw rotation. Compared with the traditional cylinder drive method, this structure has the advantages of high displacement control accuracy and stable operation. When it is necessary to sample reagents at different locations in the biological reagent storage container 25, the motor of the longitudinal sampling device 4 is started, driving the screw to rotate, causing the threaded sleeve to move along the screw axis. This, in turn, drives the lifting sliding bracket 6 to move longitudinally up and down along the slide rail 15 through the connecting slide column 23. At the same time, the sliding support 10 slides synchronously along the slide groove 11. (The sliding support 10 can be directly in the form of a slide column, only serving a guiding function, or it can adopt the same structure as the transverse sampling device 8 to ensure the smoothness of the lifting.) Stability (not elaborated here) provides stable support for the lifting sliding bracket 6, preventing it from shifting during movement. When the lifting sliding bracket 6 moves to the preset longitudinal height, the motor of the sampling lateral moving device 8 starts, driving the threaded sleeve connected to it to move, thereby pulling the sampling device 14 to move laterally along the slide groove 7 (wherein, the sampling device 14 can adopt a structure similar to a syringe and can be connected to external sampling test tubes and other structures), finally driving the sampling head 22 to move precisely to the target sampling position in the biological reagent storage container 25, realizing multi-point sampling of reagents at different depths and different lateral positions in the container, effectively improving the representativeness of the sampling, and solving the problem of one-sided test results caused by the single sampling position of the existing sampling equipment.

[0078] In one embodiment of the present invention, please refer to Figures 1-13 It also includes: an information display block 13, which is fixedly installed at the end of the push-pull limiting rod 9 and is used to display the reagent information of the corresponding biological reagent storage container 25;

[0079] And an opening and closing control mounting base 24, which is fixedly mounted on the push-pull limit rod 9 and connected to the inlet of the biological reagent storage container 25, for controlling the opening and closing of the inlet of the biological reagent storage container 25.

[0080] The information display block 13 is fixed to the end of the push-pull limit rod 9 (the information display block 13 has a small structural size, which makes it easy for staff to hold and push / pull, and also avoids collisions when the push-pull limit rod 9 rotates the information display block 13). It can display key information such as the name, concentration, and expiration date of the corresponding biological reagent storage container 25 in real time. Before sampling, the operator can directly obtain the reagent information through the block without having to check the ledger, thus improving sampling efficiency. At the same time, when the block is pressed by external force, it can automatically transmit parameters such as reagent type to the control panel 2, providing data support for the subsequent stirring control unit. The opening and closing control mounting base 24 adopts an electromagnet-controlled opening and closing structure. (Other existing automatic opening and closing structures can also be used.) It is equipped with an electromagnetic coil and a sealing valve core. Under normal conditions, the electromagnetic coil is de-energized, and the sealing valve core closes the inlet of the biological reagent storage container 25 under the action of a spring, preventing the reagent from being contaminated by the outside world and preventing reagent leakage during subsequent rotational mixing. When it is necessary to add reagents to the container or take samples, the control panel 2 supplies power to the electromagnetic coil according to the sampling command. The electromagnetic coil generates magnetic force to attract the sealing valve core to move, thereby opening the inlet of the biological reagent storage container 25. After the operation is completed, the electromagnetic coil is de-energized, and the sealing valve core automatically resets and closes the inlet. Compared with the traditional manual opening and closing structure, this design realizes the automated control of the container inlet and effectively reduces the risk of reagent contamination.

[0081] In one embodiment of the present invention, please refer to Figures 1-13 The reagent storage unit includes:

[0082] Storage compartment 16, there are multiple storage compartments 16, and the multiple storage compartments 16 are evenly distributed on the biological reagent storage and retrieval integrated machine 1;

[0083] The storage compartment 16 has a sliding cavity 17 at its top, and the push-pull limiting rod 9 is inserted into the sliding cavity 17 and slidably connected to the sliding cavity 17.

[0084] And a guide section, which is connected to the storage compartment 16 and the biological reagent storage container 25 respectively.

[0085] The guide portion includes a limiting guide portion 28 and a limiting guide groove 29, wherein the limiting guide portion 28 is fixedly installed at the bottom end of the biological reagent storage container 25;

[0086] The limiting guide groove 29 is located at the bottom end of the storage compartment 16, and the limiting guide part 28 is slidably connected to the limiting guide groove 29.

[0087] The reagent storage section is equipped with multiple evenly distributed storage compartments 16, which can simultaneously store various types of biological reagents to meet the needs of multiple batch sampling and testing. Each storage compartment 16 has a sliding cavity 17 at its top, and a push-pull limiting rod 9 is inserted into the sliding cavity 17 and can slide along it (and later, the push-pull limiting rod 9 can rotate within the sliding cavity 17). The biological reagent storage container 25 is fixedly connected to the push-pull limiting rod 9 via a U-shaped frame 26 (the structure of the end of the U-shaped frame 26 away from the biological reagent storage container 25 can be designed to adapt to the structure of the storage compartment 16 to seal the storage compartment 16 during reagent storage). A limiting guide 28 installed at its bottom is adapted to the limiting guide groove 29 at the bottom of the storage compartment 16. Pushing the push-pull limiting rod 9 moves the biological reagent storage container 25... During the movement, the limiting guide part 28 slides along the limiting guide groove 29, which can provide precise guidance for the biological reagent storage container 25 and prevent it from shaking or getting stuck during the transfer. At the same time, the structure of the storage chamber 16 is completely compatible with the structure of the biological reagent storage container 25, which can form a stable protective enclosure for the container in the reagent storage state, reducing the risk of container breakage due to external collisions (when a single biological reagent storage container 25 moves into the automatic sampling chamber 12, the space of the automatic sampling chamber 12 is large enough to be used for rotating the biological reagent storage container 25 to mix it evenly and avoid stratification). Compared with the open reagent storage structure in the prior art, the closed storage chamber 16 design of the present invention can effectively isolate external dust and microorganisms, and improve the safety of reagent storage.

[0088] In one embodiment of the present invention, please refer to Figures 1-13 The stirring control unit includes:

[0089] A control motor 5 is fixedly installed on the biological reagent storage and retrieval integrated machine 1, and a drive gear 18 is fixedly installed at the output end of the control motor 5. The drive gear 18 is located inside the automatic sampling chamber 12.

[0090] Driven gear 19, there are multiple driven gears 19, the multiple driven gears 19 are evenly distributed on the biological reagent storage and retrieval integrated machine 1, and are all located in the automatic sampling chamber 12;

[0091] The multiple driven gears 19 are respectively installed opposite to the multiple push-pull limiting rods 9, and the multiple driven gears 19 are connected to the drive gear 18 through a toothed belt 21.

[0092] And a plug-in linkage structure, which is connected to the push-pull limiting rod 9, the driven gear 19 and the biological reagent storage container 25 respectively.

[0093] The plug-in linkage structure includes a cross-shaped slot 20, a U-shaped frame 26, and a cross-shaped insert plate 27.

[0094] The number of cross slots 20 is multiple, and the multiple cross slots 20 are respectively opened on the end face of the multiple driven gears 19;

[0095] The two ends of the U-shaped frame 26 are fixedly connected to the push-pull limiting rod 9 and the biological reagent storage container 25, respectively. A cross insert plate 27 is also fixedly installed on the U-shaped frame 26. The cross insert plate 27 can be detachably connected to the cross slot 20.

[0096] When the biological reagent storage container 25 reaches the sampling station, the cross-shaped insert plate 27 is inserted into the cross-shaped slot 20. When the biological reagent storage container 25 reaches the reagent storage section, the cross-shaped insert plate 27 separates from the cross-shaped slot 20.

[0097] The stirring control unit also includes a control panel 2, which is fixedly installed on the biological reagent storage and retrieval integrated machine 1 and electrically connected to the control motor 5. It is used to control the rotation speed and rotation time of the multiple driven gears 19 driven by the control motor 5 according to the reagent type (which can be input by the information display block 13. For example, when the corresponding information display block 13 is pushed by an external force, the relevant information such as the reagent type will be sent to the control panel 2, such as when the reagent is easy to separate).

[0098] The control panel 2 is pre-stored with stirring parameters corresponding to different types of biological reagents, including stirring speed and stirring time (the display screen on the control panel 2 can also display reagent information). When the biological reagent storage container 25 is pushed to the sampling station in the automatic sampling chamber 12, the cross plate 27 on the U-shaped frame 26 is inserted into the cross slot 20 on the end face of the driven gear 19, completing the power connection. At this time, the control panel 2 retrieves the corresponding stirring parameters according to the reagent type information transmitted by the information display block 13 and sends a start command to the control motor 5. After the control motor 5 starts, it drives the drive gear 18 to rotate. The drive gear 18 drives multiple driven gears 19 to rotate synchronously through the toothed belt 21. Then, through the linkage between the cross plate 27 and the cross slot 20, the biological reagent storage container 25 is driven in the automatic sampling chamber 12. For biological reagents that are prone to stratification, the control motor 5 drives the container to rotate according to a preset speed and time, so that the components of the reagent are fully mixed. For reagents that are not prone to stratification, the motor 5 can be controlled to rotate at a low speed or not rotate at all to avoid excessive stirring affecting the activity of the reagent. After sampling, the operator pulls the push-pull limit rod 9 in the opposite direction, the cross plate 27 separates from the cross slot 20, the power connection is disconnected, and the biological reagent storage container 25 is sent back to the storage chamber 16. Compared with the fixed stirring structure in the prior art, the plug-in linkage structure of the present invention realizes the rapid separation and engagement of the stirring device and the storage container, which not only ensures the stirring and mixing effect, but also improves the flexibility of the sampling operation. The intelligent control logic of the control panel 2 can accurately adjust the stirring parameters according to the reagent type, further ensuring the accuracy of sampling and the safety of the reagent.

[0099] It should be noted that, in this invention, unless otherwise explicitly specified and limited, the terms "sliding," "rotating," "fixed," and "equipped" should be interpreted broadly. For example, they can refer to welded connections, bolted connections, or integral connections; they can refer to mechanical connections or electrical connections; they can refer to direct connections or indirect connections through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0100] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A biological reagent sampling machine, characterized in that, The biological reagent sampling machine includes a biological reagent storage and retrieval integrated machine, which consists of a reagent storage unit, an automatic sampling chamber, and a stirring control unit. The automatic sampling chamber is located between the reagent storage unit and the stirring control unit. The integrated biological reagent storage and retrieval machine is also equipped with a multi-directional sampling device, which is located in the automatic sampling chamber and is used to extract reagents from different locations within the reagent storage section. The reagent storage section is fitted with a push-pull limiting rod, and a biological reagent storage container is fixedly installed on the push-pull limiting rod; when the reagent is in storage state, the biological reagent storage container is located inside the reagent storage section; When the reagent is being sampled, an external force pushes the push-pull limit rod and moves the biological reagent storage container into the automatic sampling chamber. At this time, the stirring control unit drives the biological reagent storage container to rotate in the automatic sampling chamber according to the reagent type, so as to avoid the reagent from being separated into layers in the biological reagent storage container and affecting the accuracy of sampling.

2. The biological reagent sampling machine according to claim 1, characterized in that, The multi-directional sampling device includes: The slide rail is located inside the automatic sampling chamber, and a lifting sliding bracket is slidably installed on the slide rail, and the lifting sliding bracket is provided with a second sliding groove. A sampling lateral moving device, wherein the sampling lateral moving device is mounted on the lifting sliding bracket; And a sampling device, one end of which passes through the second slide and is fixedly connected to the sampling transverse mobile device, and the other end of which is fixedly installed with a sampling pressure head.

3. The biological reagent sampling machine according to claim 2, characterized in that, The multi-directional sampling device further includes: Slide 1 and slide 3 are respectively opened on both sides of the integrated biological reagent storage and retrieval machine, and are both connected to the automatic sampling chamber; A sliding support member, one end of which is fixedly connected to the lifting sliding bracket, and the other end of which is inserted into the slide groove three and slidably connected to the slide groove three. And a sampling vertical mobile device, which is fixedly installed on the biological reagent storage and retrieval integrated machine, and the sampling vertical mobile device is connected to the lifting sliding bracket through a connecting slide column; The connecting slide column passes through the first slide groove and is slidably connected to the first slide groove.

4. The biological reagent sampling machine according to claim 3, characterized in that, The sampling longitudinal moving device and the sampling lateral moving device have the same structure, both consisting of a motor, a screw, and a threaded sleeve; The threaded sleeve is fitted onto the screw. The motor drives the screw to rotate, thereby moving the threaded sleeve. The two threaded sleeves respectively drive the lifting sliding bracket and the sampling device to move.

5. The biological reagent sampling device according to any one of claims 1-4, characterized in that, Also includes: An information display block is fixedly installed at the end of the push-pull limiting rod and is used to display the reagent information of the corresponding biological reagent storage container; And an opening and closing control mounting base, which is fixedly mounted on the push-pull limit rod and connected to the inlet of the biological reagent storage container, for controlling the opening and closing of the inlet of the biological reagent storage container.

6. The biological reagent sampling machine according to claim 1, characterized in that, The reagent storage unit includes: The storage compartments are multiple, and the multiple storage compartments are evenly distributed on the integrated biological reagent storage and retrieval machine; The storage compartment has a sliding cavity at its top, and the push-pull limiting rod is inserted into the sliding cavity and slidably connected to the sliding cavity. And a guide section, which is connected to the storage compartment and the biological reagent storage container, respectively.

7. The biological reagent sampling machine according to claim 6, characterized in that, The guide portion includes a limiting guide portion and a limiting guide groove, and the limiting guide portion is fixedly installed at the bottom end of the biological reagent storage container; The limiting guide groove is located at the bottom end of the storage compartment, and the limiting guide part is slidably connected to the limiting guide groove.

8. The biological reagent sampling machine according to claim 1, characterized in that, The stirring control unit includes: A control motor is fixedly installed on the integrated biological reagent storage and retrieval machine, and a drive gear is fixedly installed at the output end of the control motor. The drive gear is located inside the automatic sampling chamber. Driven gears, there are multiple driven gears, the multiple driven gears are evenly distributed on the biological reagent storage and retrieval integrated machine, and all are located in the automatic sampling chamber; The multiple driven gears are respectively installed opposite to the multiple push-pull limiting rods, and the multiple driven gears are connected to the drive gear through a toothed belt; And a plug-in linkage structure, which is connected to the push-pull limiting rod, the driven gear and the biological reagent storage container respectively.

9. The biological reagent sampling machine according to claim 8, characterized in that, The plug-in linkage structure includes a cross-shaped slot, a U-shaped frame, and a cross-shaped insert plate; The number of cross slots is multiple, and the multiple cross slots are respectively opened on the end face of multiple driven gears; The two ends of the U-shaped frame are fixedly connected to the push-pull limiting rod and the biological reagent storage container, respectively, and a cross insert plate is also fixedly installed on the U-shaped frame. The cross insert plate and the cross slot can be detachably connected. When the biological reagent storage container arrives at the sampling station, the cross-shaped insert is inserted into the cross-shaped slot; when the biological reagent storage container arrives at the reagent storage section, the cross-shaped insert separates from the cross-shaped slot.

10. The biological reagent sampling machine according to claim 1, characterized in that, The stirring control unit also includes a control panel, which is fixedly installed on the biological reagent storage and retrieval integrated machine and electrically connected to the control motor. The control panel is used to control the rotation speed and rotation time of the multiple driven gears driven by the control motor according to the reagent type.

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