An extraction process of phlorotannins, alginate and fucoidan in brown algae

By combining pre-cooling with high-temperature-low-temperature-high-temperature drying, cellulase treatment, and ethanol precipitation, the problem of low extraction rates of algal proteins, alginate, and fucoidan from brown algae was solved, achieving efficient extraction while maintaining biological activity.

CN122127494APending Publication Date: 2026-06-02YANGTZE DELTA REGION INST OF TSINGHUA UNIV ZHEJIANG
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
YANGTZE DELTA REGION INST OF TSINGHUA UNIV ZHEJIANG
Filing Date
2026-04-30
Publication Date
2026-06-02

AI Technical Summary

Technical Problem

In existing technologies, the extraction rates of algal proteins, alginate, and fucoidan from brown algae are low, and the extracts lose their biological activity. Traditional methods may cause high-temperature acid hydrolysis, which may damage the structure of fucoidan and reduce its biological activity.

Method used

The extraction process was optimized to maintain the integrity of the polysaccharide chain structure by adopting a drying mode of pre-cooling followed by high-temperature-low-temperature-high-temperature, combined with cellulase treatment, pH adjustment and addition of calcium chloride, combined with ethanol precipitation, and finally freeze drying.

Benefits of technology

It significantly improved the extraction rate of effective components from brown algae, maintained the bioactivity of fucoidan, and enhanced the purity and yield of the extract.

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Abstract

This invention provides an extraction process for algal proteins, alginate, and fucoidan from brown algae, relating to the field of algae processing technology. The extraction process comprises the following steps: pre-cooling brown algae and then performing stepwise drying to obtain a brown algae sample; ultra-finely pulverizing the brown algae sample, adding cellulase, and then extracting with water, repeating the extraction to obtain an aqueous filtrate; adjusting the pH of the aqueous filtrate, filtering and separating to obtain algal proteins and a separation liquid; adding calcium chloride to the separation liquid, allowing it to stand, adding ethanol at an alcohol-to-liquid ratio of 3-4:1, incubating overnight, centrifuging to obtain alginate and a supernatant; filtering the supernatant, and freeze-drying the filtrate to obtain fucoidan.
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