Natural orifice transluminal tissue ablation device and ablation system
By designing a tissue ablation device with an adjustable puncture needle and a detection and positioning mechanism, the problem of incomplete ablation caused by the irregular shape of uterine fibroids has been solved, achieving a more efficient ablation effect and a higher surgical success rate.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 武汉拓扑转化医学研究中心有限公司
- Filing Date
- 2024-12-03
- Publication Date
- 2026-06-05
AI Technical Summary
In existing technologies, the puncture and ablation treatment of uterine fibroids is difficult to adapt to irregular shapes, resulting in some areas being unable to be effectively ablated.
Design a tissue ablation device through natural cavities, comprising a sheath, a puncture element, and a sub-puncture needle. The puncture direction of the sub-puncture needle is adjusted by a direction adjustment mechanism, and combined with a detection and positioning mechanism, to ensure precise puncture and ablation of irregularly shaped uterine fibroids.
It has improved the success rate of uterine fibroid ablation surgery, ensured the coverage and precision of ablation treatment, and reduced surgical risks.
Smart Images
Figure CN122140363A_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of medical device technology, and in particular to a tissue ablation device and ablation system via natural cavities. Background Technology
[0002] Uterine fibroids are benign growths originating from the smooth muscle tissue of the uterus. This condition primarily affects women aged 30 to 50, although it is less common in women under 20, but can still occur. Potential patients may not experience any obvious symptoms and the disease is often discovered during a physical examination. Uterine fibroids are classified primarily based on their relationship to the uterine wall, such as intramural fibroids, subserosal fibroids, and submucosal fibroids, with intramural fibroids being the most common, occurring in 60% to 70% of cases.
[0003] Most patients with uterine fibroids are asymptomatic, but some may experience symptoms such as menstrual irregularities, increased vaginal discharge, abdominal masses, and lower abdominal distension. When fibroids compress the bladder or rectum, they can cause urinary frequency, difficulty urinating, painful defecation, and constipation.
[0004] In existing methods, ultrasound can be used to locate the uterine fibroid, and then a puncture ablation device can be inserted into the fibroid for ablation. However, because uterine fibroids can come in various shapes, some areas may be unsuitable for ablation during the puncture ablation procedure. Summary of the Invention
[0005] To address the shortcomings of existing technologies, the present invention aims to provide a tissue ablation device and ablation system via natural cavities to solve the aforementioned technical problems.
[0006] To achieve the above objectives, one technical solution adopted by the present invention is: providing a tissue ablation device via natural cavities, the tissue ablation device comprising:
[0007] An operating handle, a sheath, and an ablation mechanism; one end of the sheath is connected to the operating handle, and the other end is used to enter the body through a natural cavity; the ablation mechanism is disposed in the sheath and is configured to be exposed from the other end of the sheath.
[0008] The ablation mechanism includes a puncture element and a sub-puncture needle located within the puncture element; the puncture element is used to puncture the tissue to be ablated, and the sub-puncture needle is configured to extend out from a side opening of the puncture element to puncture other areas of the tissue to be ablated; the sub-puncture needle is connected to an external ablation device, which is used to send an ablation signal to the sub-puncture needle to perform ablation on the tissue to be ablated.
[0009] The direction in which the sub-puncture needle protrudes through the side opening of the puncture member is adjustable.
[0010] Optionally, the puncture tip of the puncture member is connected to the ablation device to perform ablation on the tissue to be ablated.
[0011] Optionally, the puncture member is provided with a direction adjustment mechanism, which includes an adjustment plate, a sliding rod, a pull wire, and an adjustment knob;
[0012] The puncture device has an internal channel, the sub-puncture needle is movably disposed in the internal channel, one end of the adjusting plate is located in the internal channel, and the other end extends to the side opening, the puncture head of the sub-puncture needle is disposed towards the adjusting plate, so that the puncture head extends out of the side opening through the guidance of the adjusting plate.
[0013] The sliding rod is connected to the adjusting plate, and the sliding rod is located on the side of the adjusting plate opposite to the sub-puncture needle. The sliding rod is slidably installed on the outer wall of the puncture member.
[0014] One end of the pull cable is connected to the sliding rod, and the other end extends along the internal channel to the operating handle;
[0015] The adjustment knob is rotatably mounted on the operating handle and connected to the other end of the pull cable.
[0016] Optionally, the outer wall of the puncture member is provided with a groove, the number of grooves is two, and the two grooves are respectively arranged on opposite sides of the side opening, and the opposite ends of the sliding rod are respectively movably arranged in the two grooves.
[0017] Optionally, the number of sub-puncture needles is at least two.
[0018] Optionally, the tissue ablation device further includes a detection mechanism, which includes a detection head, a pull rod, and an adjustment knob;
[0019] The detection head is rotatably mounted on the sheath; one end of the pull rod is hinged to the detection head, and the other end extends to the operating handle and is connected to the adjustment push button;
[0020] The adjustment knob is mounted on the operating handle and is capable of linear movement.
[0021] Optionally, the detection head is provided with a negative pressure hole.
[0022] Optionally, the sheath is further provided with an auxiliary positioning mechanism, which includes a positioning needle with a spirally extended end. The end of the positioning needle can puncture into the tissue to be ablated to further locate the tissue to be ablated.
[0023] Optionally, the number of positioning needles is at least two, and the two positioning needles are located on opposite sides of the puncture member.
[0024] To achieve the above objectives, one technical solution adopted by the present invention is to provide an ablation system, the ablation system comprising an ablation device and a tissue ablation apparatus as described above;
[0025] The ablation device is electrically connected to the sub-puncture needle.
[0026] This invention provides a tissue ablation device and system via natural cavities. In this application, by adjusting the direction of the side opening of the sub-puncture needle through the puncture device, the puncture position of the sub-puncture needle in the tissue to be ablated can be adjusted, thereby adjusting the ablation treatment position of the sub-puncture needle. This makes it suitable for ablation of irregularly shaped tissues after puncture, thereby improving the success rate of the surgery. Attached Figure Description
[0027] Figure 1 This is a schematic diagram of an embodiment of a tissue ablation device via a natural cavity provided in this application;
[0028] Figure 2 yes Figure 1 A magnified view of a portion of the tissue ablation device in region II;
[0029] Figure 3 yes Figure 1 A partial enlarged view of the puncture element in the tissue ablation device shown;
[0030] Figure 4 yes Figure 1 A schematic diagram of the sub-puncture needle in the tissue ablation device shown;
[0031] Figure 5 yes Figure 1 The diagram shows the structure of the ablation device after the positioning needle extends. Detailed Implementation
[0032] To make the above-mentioned objectives, features, and advantages of this application more apparent and understandable, the specific embodiments of this application are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of this application. However, this application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this application. Therefore, this application is not limited to the specific embodiments disclosed below.
[0033] In the description of this application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicating the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.
[0034] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.
[0035] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.
[0036] In this application, unless otherwise expressly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.
[0037] It should be noted that when an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. When an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used herein are for illustrative purposes only and do not represent the only possible implementation.
[0038] Please see Figures 1-4 , Figure 1 This is a schematic diagram of an embodiment of a tissue ablation device via a natural cavity provided in this application; Figure 2 yes Figure 1 A magnified view of a portion of the tissue ablation device in region II; Figure 3 yes Figure 1 A partial enlarged view of the puncture element in the tissue ablation device shown; Figure 4 yes Figure 1 A schematic diagram of the sub-puncture needle in the tissue ablation device shown.
[0039] This application provides a tissue ablation device 10 via a natural cavity, wherein the tissue ablation device 10 includes: an operating handle 110, a sheath 120, and an ablation mechanism 130; one end (referred to as proximal end a) of the sheath 120 is connected to the operating handle 110, and the other end (referred to as distal end b) is used to enter the body via a natural cavity; the ablation mechanism 130 is disposed in the sheath 120 and is configured to be exposed from the distal end b of the sheath 120.
[0040] The ablation mechanism 130 includes a puncture member 131 and a sub-puncture needle 132 located in the puncture member 131; the puncture member 131 is used to puncture the tissue to be ablated, and the sub-puncture needle 132 is configured to extend out from the side opening 101 of the puncture member 131 to puncture other areas of the tissue to be ablated; the sub-puncture needle 132 is connected to an external ablation device, which is used to send an ablation signal to the sub-puncture needle 132 to perform ablation on the tissue to be ablated; wherein, the direction in which the sub-puncture needle 132 extends out from the side opening 101 of the puncture member 131 is adjustable.
[0041] Please refer to Figure 2 The dotted line represents the position of the puncture needle 132 after it has passed through the side opening 101 of the puncture piece 131, after the direction has been adjusted.
[0042] Therefore, in the solution of this application, by adjusting the direction of the sub-puncture needle 132 through the side opening 101 of the puncture member 131, the puncture position of the sub-puncture needle 132 in the tissue to be ablated can be adjusted, thereby adjusting the ablation treatment position of the sub-puncture needle 132, which can be applied to ablation of irregularly shaped tissues after puncture, thereby improving the success rate of the operation.
[0043] For details, please refer to Figures 2-4 .
[0044] In this embodiment, the puncture member 131 is disposed inside the sheath 120 and can extend out of the end opening of the sheath 120 along the axial direction of the sheath 120, and can also retract into the end opening of the sheath 120 along the axial direction of the sheath 120.
[0045] When the distal end b of the sheath 120 enters the preset surgical position along the designated cavity, the puncture member 131 can extend from the end opening of the sheath 120 along the axial direction of the sheath 120. The end of the puncture member 131 is the puncture head 1311, which can further puncture into the designated position in the tissue to be ablated. The puncture member 131 has an internal channel, and the sub-puncture needle 132 is movably disposed in the internal channel. The side opening 101 is opened on the outer wall near one end of the puncture head 1311. The sub-puncture needle 132 can extend or retract from the side opening 101 along the internal channel of the puncture member 131. After the puncture member 131 punctures into the designated position in the tissue to be ablated, the direction of the sub-puncture needle 132 extending from the side opening 101 and the extension length of the sub-puncture needle 132 can be adjusted to puncture the sub-puncture needle 132 to the optimal treatment position, thereby completing the subsequent ablation operation.
[0046] A direction adjustment mechanism is provided at the side opening 101 of the puncture member 131.
[0047] The direction adjustment mechanism includes an adjustment plate 1331, a sliding rod 1332, a pull wire (not shown in the figure), and an adjustment knob 1333. One end of the adjustment plate 1331 is located in the internal channel of the puncture member 131, and the other end extends to the side opening 101. The puncture tip of the sub-puncture needle 132 can face the adjustment plate 1331 and can extend out of the side opening 101 guided by the adjustment plate 1331. The sliding rod 1332 is connected to the adjustment plate 1331 and is positioned on one side of the ion puncture needle 132 behind the adjustment plate 1331. A sliding groove 1312 is provided on the side of the puncture needle 131. There are two sliding grooves 1312, and the two sliding grooves 1312 are located on opposite sides of the side opening 101. The two ends of the sliding rod 1332 are respectively set in the two sliding grooves 1312. One end of the pull wire is connected to the sliding rod 1332, and the other end can extend along the sheath tube 120 to the operating handle 110. The adjusting knob 1333 is rotatably mounted on the operating handle 110, and the other end of the pull wire is connected to the adjusting knob 1333. By rotating the adjusting knob 1333, the sliding rod 1332 can move along the sliding groove 1312 toward the operating handle 110, which can drive the adjusting piece 1331 to move toward the operating handle 110. Therefore, due to the change in the position of the adjusting piece 1331, the direction of the puncture needle 132 after it extends out of the side opening 101 can be adjusted.
[0048] In this embodiment, the number of sub-puncture needles 132 can be one or at least two, and each sub-puncture needle 132 is provided with a direction adjustment mechanism to adjust the puncture direction of the sub-puncture needle 132.
[0049] The end of the sub-puncture needle 132 furthest from the side opening 101 extends to the operating handle 110. A push button 112 is provided on the operating handle 110, and the end of the sub-puncture needle 132 furthest from the side opening 101 is connected to the push button 112. The push button 112 is configured to move linearly on the operating handle 110 (using a groove and slider structure to achieve linear movement). By manually pushing the push button 112, the operator can control the extension or retraction of the sub-puncture needle 132 from the side opening 101. Furthermore, a motion damping mechanism is provided between the push button 112 and the operating handle 110, allowing the push button 112 to move any distance and then be fixed in position with the operating handle 110.
[0050] Furthermore, the sub-puncture needle 132 can be connected to an external ablation device via a connecting wire. The ablation device can be a radiofrequency ablation device, which can send radiofrequency current to the sub-puncture needle 132 to achieve radiofrequency ablation of the tissue to be ablated. The puncture head 1311 at the end of the puncture member 131 is also connected to the ablation device, that is, the puncture head 1311 can also receive radiofrequency current to perform ablation operations.
[0051] The puncture needle 132 is provided with a plurality of ablation sections 1321 spaced apart along its axial direction. The ablation sections 1321 can be used to perform radiofrequency ablation on the tissue to be ablated.
[0052] For further details, please refer to Figure 2 .
[0053] In this embodiment, a detection mechanism 140 is also provided at the distal end b of the sheath 120. The detection mechanism 140 is used to detect and locate the tissue to be ablated.
[0054] The detection mechanism 140 includes a detection head 141, a pull rod 142, and an adjustment knob 143. The detection head 141 is rotatably mounted on the distal end b of the sheath 120. One end of the pull rod 142 is connected to the detection head 141, and the other end is located inside the sheath 120 and extends along the axial direction of the sheath 120 into the operating handle 110, and is connected to the adjustment knob 143. By adjusting the knob 143, the pull rod 142 can be driven to pull the detection head 141 to rotate, thereby improving the detection range and detection flexibility of the detection head 141.
[0055] The detection head 141 can be equipped with an ultrasonic sensing device for ultrasonic detection, thereby detecting the location and outline of the tissue to be ablated. The detection head 141 can communicate with an external display device, and the image information detected by the detection head 141 can be displayed on the external display device. The operator can confirm the puncture position and depth of the puncture element 131 based on the image information such as the location and outline of the tissue to be ablated displayed on the display device. Similarly, the operator can also determine the puncture direction and depth of the sub-puncture needle 132.
[0056] The detection head 141 is equipped with a negative pressure port 1411, which can be used to adsorb and fix tissue for subsequent puncture by the puncture device 131. The negative pressure port 1411 is connected to a negative pressure tube 1412, which extends to the operating handle 110. The negative pressure tube 1412 is also connected to a feedback device (not shown in the figure). The feedback device can detect the adsorption force at the location of the negative pressure port 1411 to determine whether the negative pressure port 1411 has attracted and fixed the tissue. When the negative pressure port 1411 has attracted and fixed the tissue, the feedback device can send a feedback signal, allowing the operator to complete the subsequent puncture and ablation of the tissue to be ablated.
[0057] Furthermore, in this embodiment, an auxiliary positioning mechanism is also provided in the sheath. Please refer to [link / reference]. Figure 5 , Figure 5 yes Figure 1The diagram shows the structure of the ablation device after the positioning needle has extended. The auxiliary positioning mechanism includes a positioning needle 151, the end of which extends spirally. The end of the positioning needle 151 can puncture the tissue to be ablated for further positioning of the tissue.
[0058] Optionally, the number of positioning needles 151 is at least two, and the two positioning needles 151 are located on opposite sides of the puncture member 131. The positioning needles 151 can be rotated to insert into the tissue to be ablated to fix the tissue to be ablated, thereby facilitating the subsequent puncture operation of the puncture member 131.
[0059] In a specific application scenario, the tissue ablation device 10 via natural cavity provided in this application can perform uterine fibroid ablation surgery via the cervix.
[0060] Specifically, firstly, the distal end b of the sheath 120 is inserted into the uterus through the cervix along the vagina, with the puncture element 131 and the positioning needle 151 both housed within the sheath 120. Then, ultrasound detection is performed through the detection mechanism 140 to locate the uterine fibroid. The negative pressure port 1411 on the detection head 141 can also be used to adhere and fix the uterine wall corresponding to the fibroid's location. The positioning needle 151 can then be rotated to puncture the fibroid, fixing it in place. Next, the puncture element 131 is used for puncture, and the sub-puncture needle 132 is released for electro-ablation. After the set electro-ablation time, the positioning needle 151 and the puncture element 131 are retrieved back into the sheath 120, the negative pressure port 1411 is closed, and the distal end b of the sheath 120 is withdrawn from the uterus, completing the ablation of the uterine fibroid.
[0061] In this scheme, the negative pressure adsorption of the negative pressure hole 1411 corresponds to the uterine wall of the uterine fibroid, which can be used to roughly locate the position of the uterine fibroid. Then, the positioning needle 151 is spirally inserted into the uterine fibroid to accurately locate the position of the uterine fibroid. This can ensure that the puncture piece 131 can be successfully inserted into the uterine fibroid and ensure the accuracy of the puncture position of the puncture piece 131, thereby improving the success rate of the operation and reducing the surgical risk.
[0062] Furthermore, based on the same inventive concept, this application also provides an ablation system. The ablation system includes an ablation device and a tissue ablation apparatus 10 as described in the preceding embodiments.
[0063] The ablation device can be electrically connected to the puncture head 1311 and the sub-puncture needle 132 of the puncture member 131, so that radio frequency current signals can be sent to the puncture head 1311 and the puncture needle 132 to perform ablation operations. In addition, the ablation device may also include an ultrasound imaging device, which can be electrically connected to the ultrasound detection component in the detection head 141, so that it can receive the image information detected by the detection head 141 and form an ultrasound image for display, so that the operator can observe it.
[0064] In summary, this application provides a tissue ablation device and system via natural cavities. In this application, by adjusting the direction of the side opening of the sub-puncture needle exiting the puncture device, the puncture position of the sub-puncture needle in the tissue to be ablated can be adjusted, thereby adjusting the ablation treatment position of the sub-puncture needle. This makes it suitable for ablation of irregularly shaped tissues after puncture, thus improving the success rate of the procedure.
[0065] The above embodiments are merely illustrative examples of the present invention and not all embodiments. The present invention may also be implemented in other specific ways or forms without departing from the spirit or essential characteristics of the invention. Therefore, the described embodiments should be considered illustrative rather than limiting in any respect. The scope of the invention should be defined by the appended claims, and any variations equivalent to the intent and scope of the claims should also be included within the scope of the invention.
Claims
1. A tissue ablation device via natural cavities, characterized in that, The tissue ablation device includes: An operating handle, a sheath, and an ablation mechanism; one end of the sheath is connected to the operating handle, and the other end is used to enter the body through a natural cavity; the ablation mechanism is disposed in the sheath and is configured to be exposed from the other end of the sheath. The ablation mechanism includes a puncture element and a sub-puncture needle located within the puncture element; the puncture element is used to puncture the tissue to be ablated, and the sub-puncture needle is configured to extend out from a side opening of the puncture element to puncture other areas of the tissue to be ablated; the sub-puncture needle is connected to an external ablation device, which is used to send an ablation signal to the sub-puncture needle to perform ablation on the tissue to be ablated. The direction in which the sub-puncture needle protrudes through the side opening of the puncture member is adjustable.
2. The tissue ablation device as described in claim 1, characterized in that, The puncture tip of the puncture device is connected to the ablation device to perform ablation on the tissue to be ablated.
3. The tissue ablation device as described in claim 2, characterized in that, The puncture device is provided with a direction adjustment mechanism, which includes an adjustment plate, a sliding rod, a pull wire, and an adjustment knob. The puncture device has an internal channel, the sub-puncture needle is movably disposed in the internal channel, one end of the adjusting plate is located in the internal channel, and the other end extends to the side opening, the puncture head of the sub-puncture needle is disposed towards the adjusting plate, so that the puncture head extends out of the side opening through the guidance of the adjusting plate. The sliding rod is connected to the adjusting plate, and the sliding rod is located on the side of the adjusting plate opposite to the sub-puncture needle. The sliding rod is slidably installed on the outer wall of the puncture member. One end of the pull cable is connected to the sliding rod, and the other end extends along the internal channel to the operating handle; The adjustment knob is rotatably mounted on the operating handle and connected to the other end of the pull cable.
4. The tissue ablation device as described in claim 3, characterized in that, The outer wall of the puncture member is provided with a sliding groove, and there are two sliding grooves. The two sliding grooves are respectively arranged on opposite sides of the side opening, and the opposite ends of the sliding rod are respectively movably arranged in the two sliding grooves.
5. The tissue ablation device as described in claim 3, characterized in that, The number of sub-puncture needles is at least two.
6. The tissue ablation device according to any one of claims 1-5, characterized in that, The tissue ablation device also includes a detection mechanism, which includes a detection head, a pull rod, and an adjustment knob. The detection head is rotatably mounted on the sheath; one end of the pull rod is hinged to the detection head, and the other end extends to the operating handle and is connected to the adjustment push button; The adjustment knob is mounted on the operating handle and is capable of linear movement.
7. The tissue ablation device as described in claim 6, characterized in that, The detection head is equipped with a negative pressure hole.
8. The tissue ablation device as described in claim 6, characterized in that, The sheath is also provided with an auxiliary positioning mechanism, which includes a positioning needle. The end of the positioning needle extends spirally and can penetrate into the tissue to be ablated to further locate the tissue.
9. The tissue ablation device as described in claim 8, characterized in that, The number of positioning needles is at least two, and the two positioning needles are located on opposite sides of the puncture member.
10. An ablation system, characterized in that, The ablation system includes an ablation device and a tissue ablation apparatus as described in any one of claims 1-9; The ablation device is electrically connected to the sub-puncture needle.