Pulmonary fibrosis model based on stem cell exosome treatment and construction method

Abstract

The application discloses a pulmonary fibrosis model based on stem cell exosome treatment and a construction method thereof, and belongs to the field of biomedical technology.The application solves the problems of low success rate of model construction, inaccurate evaluation of treatment effect and difficulty in effectively screening the best treatment preparation of the existing pulmonary fibrosis animal model construction method, and constructs a pulmonary fibrosis model capable of accurately simulating the pathological process of pulmonary fibrosis, effectively evaluating the treatment effect and mechanism of stem cell exosome by using a targeted stem cell exosome preparation modified by surface engineering and combining specific induction, application and detection steps.The model not only improves the success rate and stability of model construction, but also quantitatively evaluates the treatment effect through multidimensional detection means, provides a scientific basis for screening stem cell exosome preparations with the best treatment effect, and further promotes the research and optimization of pulmonary fibrosis treatment strategies.

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