A supramolecular complex, a preparation method thereof, a cosmetic product and application

CN122163475APending Publication Date: 2026-06-09云南白药集团上海科技有限公司
View PDF 0 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
云南白药集团上海科技有限公司
Filing Date
2024-12-06
Publication Date
2026-06-09

AI Technical Summary

Technical Problem

Existing technologies for preparing plant active ingredient complexes suffer from poor water solubility, lack of targeting, and low bioavailability. Furthermore, the ethanol injection method and the thin film dispersion method are complex and carry the risk of solvent residue.

Method used

A supramolecular complex was prepared using a high-pressure homogenization method. Through the spontaneous binding between natural plant extracts, an ordered entity was formed in which the host active ingredient molecule encapsulates the guest active ingredient molecule. By using non-covalent bonding, a spherical encapsulation complex with a hydrophilic shell and a hydrophobic cavity was formed, thereby achieving the stability of the active ingredient and transdermal absorption.

Benefits of technology

It improves the solubility, transdermal absorption rate and bioavailability of active molecules, reduces cytotoxicity, simplifies the preparation process, is suitable for industrial production, and avoids the risk of solvent residue.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN122163475A_ABST
    Figure CN122163475A_ABST
Patent Text Reader

Abstract

This invention provides a supramolecular complex, its preparation method, cosmetic products, and applications. The supramolecular complex is formed by the non-covalent bonding of a host active ingredient molecule and a guest active ingredient molecule, with the host active ingredient molecule encapsulating the guest active ingredient molecule. Compared to traditional supramolecular amphiphilic compounds, the method of this invention possesses all the advantages of traditional supramolecular compounds, such as improved solubility, improved bioavailability, and improved stability. Furthermore, it can fully utilize the activity of the two host and guest active ingredient molecules or generate new activities without introducing other components besides the host and guest active ingredients. This method utilizes the compatibility relationship between natural plant extracts, forming a novel natural product through spontaneous non-covalent bonding. The bonding process uses only physical intervention, without any chemical methods. The host and guest active ingredient molecules have a synergistic effect, which is more conducive to their utilization in cosmetics.
Need to check novelty before this filing date? Find Prior Art