Chemical analysis automatic sampling device and system

Abstract

The application discloses a chemical medicine analysis automatic sampling device and system, which comprises a bottom frame, fixed frames and limiting cylinders which are arranged at the top of the bottom frame, and an adjusting mechanism which comprises a first servo motor installed at the top of the fixed frame. The application has the beneficial effects that: the first servo motor and the second servo motor cooperate with the screw rod transmission and are driven by the hydraulic cylinder, so that the longitudinal, transverse and multidimensional position adjustment of the sampling needle tube is realized; the efficient transmission of the servo motor and the screw rod and the limiting effect of the guide component guarantee the adjustment accuracy; the fastening frame, the L-shaped frame and the multiple sliding components provide stable installation and support; the four cylindrical connecting rods balanceably support the sampling needle tube at multiple points, so that the components are not loose and the needle tube is not bent and shaken during the sampling process; the electric push rod drives the piston pull rod to realize automatic suction sampling, accurately controls the sampling amount, replaces manual operation and reduces sample pollution.

Description

Technical Field

[0001] This invention belongs to the field of chemical pharmaceutical analysis technology, specifically relating to an automatic sampling device and system for chemical pharmaceutical analysis. Background Technology

[0002] In the production and quality testing of chemical pharmaceuticals, it is necessary to conduct batch and continuous sampling and analysis of the pharmaceuticals to ensure that the quality of each batch of pharmaceuticals meets the standards.

[0003] A drug analysis sampler, disclosed in patent publication number CN221260531U, includes a sampling stage with a support cylinder fixedly connected to it. A moving component is located inside the support cylinder, and a sampling component is located on one side of the moving component. The sampling component includes a housing with a fixed rod fixedly connected to its outer end face. A first motor is fixedly connected to one side of the housing, and a gear is fixedly connected to the output shaft of the first motor. One side of the gear meshes with a rack movably fitted inside the housing. A push plate is fixedly connected to the bottom of the rack, and two push rods are fixedly connected to the push plate. A sampling tube is movably fitted outside the push rods, and a fixed ring is fixedly fitted outside the sampling tubes. A needle is fixedly fitted to the bottom of the sampling tubes. A piston block is fixedly connected to one end of the push rods that extends into the sampling tubes, and a limiting spring is movably fitted on the push rods.

[0004] Most existing chemical sampling devices can only be used with a single type of bottle, which cannot meet diverse sampling needs and limits the improvement of sampling and testing efficiency. Summary of the Invention

[0005] The purpose of this invention is to provide an automatic sampling device and system for chemical drug analysis, which improves the system's adaptability to different sizes of medicine bottles and increases sampling and detection efficiency.

[0006] To achieve the above objectives, the present invention provides the following technical solution: an automatic sampling device for chemical analysis, comprising... The base frame has fixed frames and limiting cylinders that are spaced apart on its top. The adjustment mechanism includes a first servo motor mounted on the top of a fixed frame, the output shaft of which passes through the fixed frame and is connected to a first lead screw; a first threaded seat threadedly connected to the first lead screw; a hydraulic cylinder mounted on the front surface of the first threaded seat; a fastening frame located at the output end of the hydraulic cylinder; a second servo motor mounted on the inner side of the fastening frame; a second lead screw located on the output shaft of the second servo motor; a second threaded seat threadedly connected to the second lead screw; a connecting rod and an electric push rod mounted at the bottom of the second threaded seat; a sampling needle located at the bottom of the connecting rod; and a piston rod located at the output end of the electric push rod capable of drawing liquid chemicals.

[0007] As a preferred technical solution of the present invention, it further includes a first slide groove formed on the fixed frame and a first slide plate disposed on the rear surface of the first threaded seat and slidably connected to the first slide groove.

[0008] As a preferred technical solution of the present invention, it further includes an L-shaped bracket disposed at the bottom of the first threaded seat, and the fastening bracket and the L-shaped bracket are provided with sliding components.

[0009] As a preferred technical solution of the present invention, the sliding component includes a second sliding groove opened on the top of the L-shaped frame and a second sliding plate disposed at the bottom of the fastening frame that can slide within the second sliding groove.

[0010] As a preferred embodiment of the present invention, it further includes a guide rod installed on the inner side of the fastener and a guide hole opened inside the second threaded seat for the guide rod to pass through.

[0011] As a preferred embodiment of the present invention, the connecting rod is a cylindrical structure, and four connecting rods are provided.

[0012] As a preferred embodiment of the present invention, the length of the first threaded seat is less than the length of the fixed frame, and the front end of the first threaded seat is located outside the fixed frame.

[0013] This invention also discloses an automated sampling system for chemical analysis, including an automated sampling device for chemical analysis, and further comprising... The detection module is used to detect the composition and purity of the sample after sampling. The control module is electrically connected to the automatic sampling device and the detection module respectively; the control module includes a controller, a touch screen display and a wireless communication unit.

[0014] Compared with the prior art, the beneficial effects of the present invention are: The sampling needle is adjusted longitudinally, laterally, and backward in multiple dimensions by means of a first servo motor, a second servo motor, a lead screw drive, and a hydraulic cylinder drive. The efficient transmission of the servo motor and lead screw, as well as the limiting function of the guide components, ensures adjustment accuracy. The fastening frame, L-shaped frame, and multiple sets of sliding components provide stable installation and support. Four columnar connecting rods provide balanced support for the sampling needle at multiple points, ensuring that the components do not loosen and the needle does not bend or shake during sampling. The electric push rod drives the piston rod to achieve automated sampling, accurately control the sampling volume, replace manual operation, and reduce sample contamination. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the first axial side structure of the present invention; Figure 2This is a schematic diagram of the second axial side structure of the present invention; Figure 3 This is a partial structural diagram of the present invention. Figure 1 ; Figure 4 This is a partial structural diagram of the present invention. Figure 2 ; Figure 5 For the present invention Figure 2 A schematic diagram of a local structure in the image; In the picture: 1. Base frame; 2. Fixed frame; 21. First servo motor; 210. First lead screw; 22. First slide groove; 3. First threaded seat; 31. First slide plate; 32. L-shaped frame; 320. Second slide groove; 4. Fastening frame; 41. Second servo motor; 410. Second lead screw; 42. Guide rod; 43. Second slide plate; 5. Hydraulic cylinder; 6. Second threaded seat; 61. Connecting rod; 62. Guide hole; 7. Sampling needle tube; 8. Electric push rod; 81. Piston rod; 9. Limiting cylinder. Detailed Implementation

[0016] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0017] Please see Figures 1 to 5 This invention provides an automatic sampling device for chemical drug analysis, comprising: The base frame 1 provides a stable support foundation for the entire device, ensuring that the device is not prone to shaking during sampling. This lays the structural foundation for the stable operation and accurate sampling of subsequent components. The top of the base frame 1 is equipped with spaced fixed frames 2 and limiting cylinders 9, which clearly define the functional areas of the fixed frames 2 and limiting cylinders 9 and prevent them from interfering with each other. The fixed frames 2 provide a stable mounting carrier for the adjustment mechanism, ensuring the installation stability of the adjustment mechanism. The limiting cylinders 9 can initially limit the position of the medicine bottle to prevent it from shifting when placed, ensuring that the sampling needle 7 can be accurately aligned with the mouth of the medicine bottle. The adjustment mechanism includes a first servo motor 21 mounted on the top of the fixed frame 2. The first servo motor 21 provides precise power output to the adjustment mechanism. The servo motor features high control precision and fast response speed, ensuring the accuracy of subsequent position adjustments and adapting to the sampling position requirements of different sized medicine bottles. The output shaft of the first servo motor 21 directly passes through the fixed frame 2 and connects to the first lead screw 210, resulting in a short transmission path and low power loss, efficiently converting the motor's rotational motion into the linear drive power of the lead screw. The fixed frame 2 provides auxiliary support for the connection between the motor output shaft and the lead screw, improving transmission stability. The first threaded seat 3, threadedly connected to the first lead screw 210, converts the rotational motion of the first servo motor 21 into the first thread... The linear movement of seat 3 ensures high transmission accuracy and smooth operation, enabling precise longitudinal position adjustment of the first threaded seat 3 and subsequent sampling components. The hydraulic cylinder 5, mounted on the front surface of the first threaded seat 3, possesses advantages such as high driving force and smooth operation. Mounted on the front surface of the first threaded seat 3, it moves synchronously with the first threaded seat 3 and can independently provide telescopic power in the forward and backward directions, expanding the movement dimension of the sampling components. The fastening bracket 4, located at the output end of the hydraulic cylinder 5, acts as a load-bearing component, transmitting the driving force of the hydraulic cylinder 5 to subsequent components such as the second servo motor 41 and the sampling needle tube 7, while providing a stable mounting platform for these components. Its secure connection to the output end of the hydraulic cylinder 5 ensures that it does not loosen during power transmission. To ensure the positional stability of the sampling components, a second servo motor 41 is installed on the inner side of the fastening frame 4, and a second lead screw 410 is set on the output shaft of the second servo motor 41. The second lead screw 410 can efficiently convert the rotational motion of the second servo motor 41 into linear drive power, with high transmission efficiency and high precision, providing stable power support for the lateral movement of the second threaded seat 6. The second threaded seat 6 is threadedly connected to the second lead screw 410, and a connecting rod 61 and an electric push rod 8 are installed at the bottom of the second threaded seat 6. A sampling needle tube 7 is set at the bottom of the connecting rod 61, realizing the horizontal and lateral precise movement of the second threaded seat 6, the bottom sampling needle tube 7, the electric push rod 8, and other components. A piston rod 81 that can draw liquid chemicals is set at the output end of the electric push rod 8. The mounting base 6 provides a stable foundation for the connecting rod 61 and the electric push rod 8, ensuring that both are installed accurately and securely. The integrated installation of the connecting rod 61 and the electric push rod 8 concentrates the support and sampling power components of the sampling needle tube 7, facilitating synchronous position adjustment and improving the compactness of the device structure. The connecting rod 61 provides vertical support and positioning for the sampling needle tube 7, ensuring that the sampling needle tube 7 always remains vertical and preventing bending or tilting during sampling. As the component that directly contacts the sample, the sampling needle tube 7 has a simple structure, is easy to clean and disinfect, and can reduce the risk of cross-contamination between different samples. The electric push rod 8 drives the piston rod 81 to achieve reciprocating motion, which can precisely control the movement stroke of the piston rod 81, thereby precisely controlling the sampling amount and improving sampling accuracy.Automated suction methods replace manual operation, reducing human contact with chemicals, lowering the risk of contamination, and improving sampling efficiency.

[0018] In this embodiment, a first slide groove 22 is provided on the fixed frame 2, and a first slide plate 31 is provided on the rear surface of the first threaded seat 3 and slidably connected to the first slide groove 22. The first slide plate 31 and the first slide groove 22 slide together to form a guide and limit structure. On the one hand, it reduces the frictional resistance between the first threaded seat 3 and the fixed frame 2, making the first threaded seat 3 move more smoothly; on the other hand, it further improves the moving accuracy of the first threaded seat 3 and ensures the adjustment accuracy of the sampling component.

[0019] In this embodiment, an L-shaped frame 32 is also provided at the bottom of the first threaded seat 3. Sliding components are provided on the fastening frame 4 and the L-shaped frame 32. The sliding components can reduce the relative friction between the fastening frame 4 and the L-shaped frame 32, making the fastening frame 4 move more smoothly in the back and forth process and reducing power loss. At the same time, it plays a guiding role in the movement of the fastening frame 4, preventing the fastening frame 4 from deviating when it moves, and ensuring the positional accuracy of the sampling needle tube 7.

[0020] In this embodiment, the sliding component includes a second sliding groove 320 opened on the top of the L-shaped frame 32 and a second sliding plate 43 disposed at the bottom of the fastening frame 4 that can slide within the second sliding groove 320. The second sliding plate 43 and the second sliding groove 320 are precisely matched to realize smooth sliding between the fastening frame 4 and the L-shaped frame 32 and reduce friction and wear. At the same time, the cooperation of the two can play a vertical limiting role for the fastening frame 4, preventing the fastening frame 4 from shaking vertically during operation and ensuring the stability of the sampling needle tube 7.

[0021] In this embodiment, a guide rod 42 is installed on the inner side of the fastening frame 4, and a guide hole 62 is opened inside the second threaded seat 6 for the guide rod 42 to pass through. The guide hole 62 and the guide rod 42 are precisely matched, so that the second threaded seat 6 can slide smoothly along the guide rod 42. The guide rod 42 plays a dual role of limiting and guiding the second threaded seat 6, further improving the movement accuracy of the second threaded seat 6 and ensuring the lateral adjustment accuracy of the sampling needle tube 7.

[0022] In this embodiment, the connecting rod 61 is a cylindrical structure, and four connecting rods 61 are provided. The cylindrical connecting rod 61 has stable mechanical properties and strong load-bearing capacity, which can effectively support the sampling needle tube 7. The four connecting rods 61 are evenly distributed, which can provide multi-point balanced support for the sampling needle tube 7, avoiding bending or displacement of the sampling needle tube 7 due to single-point force, and further improving the installation stability and sampling accuracy of the sampling needle tube 7.

[0023] In this embodiment, the length of the first threaded seat 3 is less than the length of the fixed frame 2, and the front end of the first threaded seat 3 is located outside the fixed frame 2. The shorter length of the first threaded seat 3 compared to the fixed frame 2 prevents collisions and interference with both ends of the fixed frame 2 during movement, ensuring sufficient travel for the first threaded seat 3 and expanding the longitudinal adjustment range of the sampling components. The front end of the first threaded seat 3 being located outside the fixed frame 2 allows components such as the fastening frame 4 and the sampling needle 7 to fully extend out of the fixed frame 2, facilitating sampling of medicine bottles outside the fixed frame 2 and increasing the applicability of the device.

[0024] An automated sampling system for chemical analysis includes an automated sampling device for chemical analysis, and further includes... The detection module is used to detect the composition and purity of the sample after sampling. As the core detection component of the system, the detection module can directly connect to the sample after sampling to achieve seamless connection between sampling and detection. There is no need for manual sample transfer, which reduces the risk of contamination or leakage during sample transfer and improves detection efficiency. The control module is electrically connected to both the automatic sampling device and the detection module. It receives real-time operating status signals from both modules and accurately issues control commands, ensuring seamless coordination between them and improving system stability and reliability. The control module includes a controller, a touchscreen display, and a wireless communication unit. The touchscreen provides an intuitive interface for operators to set sampling parameters (such as sampling volume and vial specifications), view system operating status (such as sampling progress and component working status), and receive test results. This user-friendly interface reduces the difficulty of operation. The wireless communication unit enables data transmission and remote control between the system and a remote monitoring terminal. Operators can monitor system operation and receive test results in real-time without on-site supervision, while also remotely issuing control commands. This enhances system management convenience and flexibility, making it suitable for large-scale batch sampling and testing scenarios.

[0025] The working principle and usage process of this invention are as follows: During use, the operator sets system parameters, including sampling volume and bottle specifications, via a touchscreen display. The system is then started, and the bottle to be sampled is placed within the limiting cylinder 9 for initial positioning. The controller controls the first servo motor 21 to start, driving the first lead screw 210 to rotate, causing the first threaded seat 3 to slide along the first slide groove 22, adjusting the position of the sampling needle tube 7. The controller controls the hydraulic cylinder 5 to start, driving the fastening frame 4 to slide along the second slide groove 320 of the L-shaped frame 32 via the second sliding plate 43, adjusting the front-to-back position of the sampling needle tube 7. The controller controls the second servo motor 41 to start, driving the second lead screw 410 to rotate, causing the second threaded seat 6 to slide along the guide rod 42, adjusting the horizontal position of the sampling needle tube 7. After the sampling needle tube 7 moves directly above the bottle, the controller 401 controls the electric push rod 8 to start, driving the piston rod 81 to move upwards, creating a negative pressure inside the sampling needle tube 7, and simultaneously inserting the sampling needle tube 7 into the bottle to complete the sampling.

[0026] Although embodiments of the invention have been shown and described (see the detailed description above), it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An automatic sampling device for chemical analysis, characterized in that: include The base frame (1) is equipped with a fixed frame (2) and a limiting cylinder (9) that are spaced apart on the top of the base frame (1). The adjustment mechanism includes a first servo motor (21) installed on the top of the fixed frame (2), and the output shaft of the first servo motor (21) passes through the fixed frame (2) and is connected to a first lead screw (210), a first threaded seat (3) threadedly connected to the first lead screw (210), a hydraulic cylinder (5) installed on the front surface of the first threaded seat (3), a fastening frame (4) set at the output end of the hydraulic cylinder (5), a second servo motor (41) installed on the inner side of the fastening frame (4), a second lead screw (410) set on the output shaft of the second servo motor (41), a second threaded seat (6) threadedly connected to the second lead screw (410), a connecting rod (61) and an electric push rod (8) installed at the bottom of the second threaded seat (6), a sampling needle tube (7) set at the bottom of the connecting rod (61), and a piston rod (81) set at the output end of the electric push rod (8) for drawing liquid chemicals.

2. The automatic sampling device for chemical analysis according to claim 1, characterized in that: It also includes a first groove (22) opened on the fixed frame (2) and a first slide plate (31) disposed on the rear surface of the first threaded seat (3) and slidably connected to the first groove (22).

3. The automatic sampling device for chemical analysis according to claim 1, characterized in that: It also includes an L-shaped bracket (32) disposed at the bottom of the first threaded seat (3), and sliding components are provided on the fastening bracket (4) and the L-shaped bracket (32).

4. The automatic sampling device for chemical analysis according to claim 3, characterized in that: The sliding component includes a second slide groove (320) opened on the top of the L-shaped frame (32) and a second slide plate (43) disposed at the bottom of the fastening frame (4) and capable of sliding within the second slide groove (320).

5. The automatic sampling device for chemical analysis according to claim 1, characterized in that: It also includes a guide rod (42) installed on the inner side of the fastener (4) and a guide hole (62) opened inside the second threaded seat (6) for the guide rod (42) to pass through.

6. The automatic sampling device for chemical analysis according to claim 1, characterized in that: The connecting rod (61) is a cylindrical structure, and there are four connecting rods (61).

7. The automatic sampling device for chemical analysis according to claim 1, characterized in that: The length of the first threaded seat (3) is less than the length of the fixed frame (2), and the front end of the first threaded seat (3) is located outside the fixed frame (2).

8. An automated sampling system for chemical analysis, characterized in that: Including the automated chemical sampling device for analysis as described in any one of claims 1-7, further comprising: The detection module is used to detect the composition and purity of the sample after sampling. The control module is electrically connected to the automatic sampling device and the detection module respectively; the control module includes a controller, a touch screen display and a wireless communication unit.

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