Enhanced matrix removal (EMR) cartridges

By using EMR columns and blended adsorbents, the problems of insufficient matrix removal and target loss in food samples are solved, achieving efficient and rapid sample preparation and purification, which is suitable for the analysis of multiple types of pollutants with multiple residues.

CN122180879APending Publication Date: 2026-06-09AGILENT TECHNOLOGIES INC
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Patent Information

Application Number
CN202480071944.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Priority Date
2023-11-15
Filing Date
2024-11-11
Publication Date
2026-06-09

AI Technical Summary

Technical Problem

Existing technologies for analyzing chemical contaminants in food samples suffer from problems such as insufficient matrix removal, time-consuming and labor-intensive sample preparation, incomplete matrix purification, and severe target loss. In particular, it is difficult to achieve efficient and rapid sample preparation and purification in complex food matrices.

Method used

An enhanced matrix removal (EMR) hybrid-mode permeation purification method is adopted, using EMR columns and blended adsorbents such as EMR-lipids, Carbon S, N-propylethylenediamine (PSA), and EC-C18 to remove the matrix through multiple interaction mechanisms, simplifying the sample preparation process and improving target recovery and purification efficiency.

Benefits of technology

It achieves efficient matrix removal from complex food matrices, improves target recovery rate, simplifies sample preparation process, reduces time and effort consumption, and reduces matrix effect and instrument contamination risk. It is suitable for high-throughput analysis of multiple types and residual pollutants.

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Abstract

In some examples, the method includes specifying an adsorbent formulation for food contaminant analysis of a target category, and utilizing an enhanced matrix removal (EMR) mixed mode penetrance purification and the specified adsorbent formulation. In other examples, an EMR cartridge can include a specified adsorbent formulation for food contaminant analysis of a target category. The EMR cartridge can utilize an EMR mixed mode penetrance purification and the specified adsorbent formulation.
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