A medicine inspection sample pollution prevention and control processing device

Abstract

The application relates to the technical field of medicine inspection, and discloses a medicine inspection sample pollution prevention and control treatment device, which comprises a bottom plate, a plurality of supporting rods and a supporting frame. The top of each supporting rod is fixedly connected with an L-shaped plate. A moving assembly is arranged on the inner wall of the L-shaped plate. A moving plate is arranged on the left side of the moving assembly. A rotating assembly is arranged on the inner wall of the L-shaped plate. A plurality of placing assemblies are arranged on the inner wall of the rotating assembly. A fixed plate is fixedly connected to the right side of the L-shaped plate. A folding and unfolding assembly is arranged on the top of the fixed plate. In the application, the device is suitable for multiple scene extraction, improves the use flexibility, and is provided with movable and liftable extraction supports and a folding and unfolding extraction pipe, so that the sample can be extracted flexibly in different specifications of medicine containers and open medicine pools. The moving assembly and the lifting assembly are matched, the extraction height and the horizontal position can be freely adjusted, the sampling dead angle is eliminated, and the device is suitable for different inspection scenes and equipment layouts.

Description

Technical Field

[0001] This invention relates to the field of pharmaceutical testing technology, and in particular to a device for preventing and controlling contamination of pharmaceutical testing samples. Background Technology

[0002] Drug testing samples are generally drawn from drug containers or drug reaction tanks. Drug testing samples refer to a small, representative sample drawn according to prescribed methods from drug raw materials, semi-finished products, finished products, formulation reaction tanks, drug solution storage tanks, or various drug packaging containers for drug quality inspection, component analysis, purity testing, impurity inspection, microbial limit testing, and contamination screening. During the extraction, transportation, distribution, and testing processes, drug testing samples are highly susceptible to exogenous contamination and batch-to-batch cross-contamination caused by environmental factors, equipment, and manual operation, leading to distorted test data and misinterpretations, seriously affecting drug quality evaluation and medication safety. Traditional manual sampling and simple equipment cannot achieve closed, standardized, and contamination-free operations, failing to meet the high precision and cleanliness requirements of drug testing. Drug testing sample contamination prevention and control detection and processing devices achieve contamination prevention and control throughout the entire process of sample extraction, filtration, quantification, transportation, and testing, ensuring the authenticity, accuracy, and reliability of test results.

[0003] Drug testing sample processing devices suffer from poor compatibility. Traditional sampling equipment can only accommodate containers of a single size or fixed reagent pools, failing to adapt to drug containers of different diameters and volumes, or open reaction pools. The fixed sampling location and lack of flexibility easily lead to sampling dead zones and insufficient sample contact. Furthermore, the risk of contamination is high. During manual sampling or sampling with simple equipment, sampling tubes and reagent addition lines are prone to cross-contamination with the external environment and non-target samples, causing exogenous contamination. Simultaneously, the sampling lines lack dedicated storage and cleaning filtration structures, allowing residual reagents to easily lead to batch-to-batch cross-contamination, affecting test results. Accuracy issues include: low quantitative control precision, with reagent addition and sample extraction relying heavily on manual operation, making accurate quantification difficult and prone to reagent overdose, sample waste, or insufficient sampling, increasing testing costs and reducing data reliability; inconvenient sample tube placement and replacement, lack of stable limiting and quick-change structures, resulting in messy placement, easy tipping and breakage during batch testing, low replacement efficiency, and inability to meet the needs of continuous multiple sampling; and non-adjustable equipment height and position, with fixed sampling bracket height and limited movement, making it difficult to adapt to different operating table heights and sampling points, resulting in poor operational convenience and affecting testing efficiency.

[0004] To address the aforementioned issues, a device for preventing and controlling contamination of drug testing samples is proposed. Summary of the Invention

[0005] To overcome the above shortcomings, this invention provides a drug testing sample contamination prevention and treatment device, which aims to improve the problems of poor sampling adaptability, high risk of contamination, low quantitative control accuracy, inconvenient sample tube placement and replacement, and non-adjustable equipment position and height of traditional drug testing sample processing devices, which seriously affect the accuracy, efficiency and ease of operation of the test.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a drug testing sample contamination prevention and treatment device, comprising a base plate, multiple support rods, and a support frame. An L-shaped plate is fixedly connected to the top of each support rod. A movable component is provided on the inner wall of the L-shaped plate. A movable plate is installed on the left side of the movable component. A rotating component is provided on the inner wall of the L-shaped plate. Multiple placement components are provided on the inner wall of the rotating component. A fixed plate is fixedly connected to the right side of the L-shaped plate. A retraction component is provided on the top of the fixed plate. A lifting component is provided on the right side of the inner wall of the base plate. A water pump is fixedly connected to the top right side of the L-shaped plate. A connecting pipe 1 is fixedly connected to the inner wall of the device. An inlet valve is fixedly installed through the outer wall of the connecting pipe 1. A filter chamber is fixedly connected to the outer wall of the connecting pipe 1. A filter plate is installed on the inner wall of the filter chamber. A liquid outlet pipe 2 is fixedly installed on the inner wall of the filter chamber. A reaction chamber is fixedly connected to the outer wall of the liquid outlet pipe 2. A connecting pipe 3 is fixedly connected to the inner wall of the reaction chamber. A connecting pipe 2 is fixedly connected to the inner wall of the connecting pipe 3. A metering component is provided at the bottom of the outer wall of the connecting pipe 2. A squeezing component is provided at the bottom of the metering component. A display panel is fixedly connected to the top front side of the moving plate. A detector is fixedly connected to the bottom right side of the moving plate.

[0007] As a further description of the above technical solution: The lifting assembly includes a sleeve rod, which is fixedly connected to the right side of the inner wall of the base plate. A toothed rod is slidably connected to the inner wall of the sleeve rod. A connecting frame is fixedly connected to the top of the outer wall of the sleeve rod. A gear is installed on the rear side of the inner wall of the connecting frame. A connecting rod is fixedly connected to the inner wall of the gear. A ratchet is fixedly connected to the left side of the connecting rod. A locking block one is engaged with the inner wall of the ratchet. A locking block two is engaged with the inner wall of the ratchet. A spring one is hung on the outer wall of the locking block two. A handle is installed on the outer wall of the locking block one. Universal wheels are fixedly connected to the four corners of the bottom of the base plate. A handrail is fixedly connected to the left side of the inner wall of the base plate.

[0008] As a further description of the above technical solution: The take-up and take-down assembly includes a second motor, which is fixedly connected to the top rear side of the fixed plate. Two trapezoidal blocks are fixedly connected to the top front side of the second motor. A drive wheel is fixedly connected to the output end of the second motor. A belt is fitted on the outer wall of the drive wheel, and a driven wheel is fitted on the inner wall of the belt. A winding roller is installed on the inner wall of each of the two trapezoidal blocks. An extraction tube is wound on the outer wall of the winding roller, and a pump head is fixedly installed on the outer wall of the extraction tube.

[0009] As a further description of the above technical solution: The rotating assembly includes a motor five, which is fixedly connected to the inner wall of the base plate. A bevel gear one is fixedly connected to the output end of the motor five. A bevel gear two is rotatably connected to the inner wall of the L-shaped plate. A rotating disk is fixedly connected to the outer wall of the bevel gear two. A limit ring is installed on the outer wall of the rotating disk.

[0010] As a further description of the above technical solution: The placement assembly includes multiple placement blocks, which are fixedly connected to the inner wall of the rotating disk. Multiple limiting blocks are slidably connected to the inner wall of each placement block, and multiple springs are installed on the inner wall of each placement block. A sample tube is inserted into the inner wall of each placement block, and a tube cap is snapped onto the top of the outer wall of the sample tube.

[0011] As a further description of the above technical solution: The quantitative component includes a connecting block three, which is fixedly connected to the bottom of the outer wall of the connecting tube two. The bottom of the connecting block three is fixedly connected to the connecting block two. The inner wall of the connecting block two is fixedly connected to a motor four. The output end of the motor four is fixedly connected to an eccentric wheel two. The outer wall of the eccentric wheel two is provided with a lifting column. The top of the lifting column is fixedly connected to a moving rod. The bottom of the outer wall of the moving rod is fitted with a spring two. The top of the moving rod is fixedly connected to a quantitative cylinder. The top of the outer wall of the moving rod is slidably connected to a connecting column. The inner wall of the connecting column is fixedly connected to a liquid guide tube.

[0012] As a further description of the above technical solution: The extrusion assembly includes a connecting block 1, which is fixedly connected to the bottom of a connecting block 2. A motor 3 is fixedly connected to the right side of the inner wall of the connecting block 1. An eccentric wheel 1 is fixedly connected to the output end of the motor 3. A connecting rod 1 is rotatably connected to the outer wall of the eccentric wheel 1. A connecting rod 2 is rotatably connected to the inner wall of the connecting rod 1. A push plate is fixedly connected to the inner wall of the connecting rod 2. A liquid outlet pipe 1 is installed on the front side of the connecting block 1.

[0013] As a further description of the above technical solution: The moving component includes a motor, which is fixedly connected to the top front side of the L-shaped plate. A threaded rod is fixedly connected to the output end of the motor, and a threaded block is threadedly connected to the outer wall of the threaded rod. A slider is fixedly connected to the rear right side of the moving plate.

[0014] As a further description of the above technical solution: The rack and gear are meshed together, the connecting rod passes through the inner wall of the connecting frame and is fixedly connected to the inner wall of the gear, and the spring is hung on the outer wall of the locking block.

[0015] As a further description of the above technical solution: The connecting column is fixedly connected to the top of the inner wall of the second connecting block, the liquid guide tube passes through the inner wall of the second connecting block, and the metering cylinder is set on the inner wall of the third connecting block.

[0016] The present invention has the following beneficial effects: 1. In this invention, the sampling is adapted to multiple scenarios, improving the flexibility of use. The control and processing device is equipped with a movable and liftable sampling bracket and a retractable sampling tube, which can flexibly extract samples from different sizes of drug containers and open drug pools. The moving component and the lifting component work together to freely adjust the sampling height and horizontal position, eliminate sampling dead angles, and adapt to different testing scenarios and equipment layouts.

[0017] 2. In this invention, pollution control is implemented throughout the entire process to ensure the accuracy of testing. An independent filtration chamber and filter plate are set up to pre-treat the extracted liquid and detection reagent to remove impurities and sources of contamination. The extraction tube uses a dedicated take-up and put-down assembly to avoid contamination from exposed pipelines. The sample tube uses a sealed tube cap and a limiting and fixing structure to reduce external contact. The entire process from sampling and transfer to reaction reduces the risk of cross-contamination and external contamination.

[0018] 3. In this invention, precise quantitative sampling and reagent addition reduce sample waste. The quantitative component and the squeezing component work together to achieve precise quantitative addition of the detection reagent and precise quantitative extraction of the sample, avoiding reagent overdose and sample waste. The quantitative structure is stable and controllable, ensuring that the single sampling amount and dosage are consistent, and improving the repeatability and reliability of test data.

[0019] 4. In this invention, continuous multiple sampling is supported, which improves the testing efficiency. The rotating component drives the multi-station placement component to circulate and change positions, which can place multiple sample tubes at the same time, realizing continuous multiple automatic sampling without frequent shutdowns for replacement. The sample tube adopts a quick-connect limiting structure, which makes insertion and removal convenient and greatly improves the efficiency of batch sample processing.

[0020] 5. In this invention, the structure is stable and adjustable, and the operation is convenient and safe. The control and treatment device is equipped with universal wheels and a handle for easy movement and transfer. The lifting component adopts a ratchet self-locking structure, and the height is stable and does not slip after adjustment. The placement component has an elastic limit block to adapt to sample tubes of different diameters, and it is firmly fixed and not easy to tip over. The overall integrated design simplifies the operation process and reduces the intensity of manual operation and the error rate.

[0021] 6. This invention features high functional integration and wide applicability. It integrates sample extraction, filtration and purification, quantitative dosing, quantitative sampling, sample tube placement and replacement, and position and height adjustment. It is suitable for various scenarios such as pharmaceutical production, distribution, and testing institutions, and meets the pre-testing processing needs of various drug samples, including injectables, oral preparations, and traditional Chinese medicine extracts. Attached Figure Description

[0022] Figure 1 This is a perspective view of the base plate of a drug testing sample contamination prevention and treatment device proposed in this invention; Figure 2 This is a schematic diagram of an L-shaped plate structure for a drug testing sample contamination prevention and treatment device proposed in this invention; Figure 3 This is a schematic diagram of the moving plate structure of a drug testing sample contamination prevention and treatment device proposed in this invention; Figure 4 In this invention Figure 3 Enlarged view of point A in the middle; Figure 5 This is a schematic diagram of the rotating component structure of a drug testing sample contamination prevention and control device proposed in this invention; Figure 6 This is a schematic diagram of the spring three-section structure of a drug testing sample contamination prevention and control treatment device proposed in this invention; Figure 7 This is a schematic diagram of the reaction chamber structure of a drug testing sample contamination prevention and treatment device proposed in this invention; Figure 8 This is a schematic cross-sectional view of the connecting block of a drug testing sample contamination prevention and control device proposed in this invention. Figure 9 This is a schematic diagram of the extrusion assembly structure of a drug testing sample contamination prevention and control treatment device proposed in this invention; Figure 10 This is a schematic diagram of the quantitative component structure of a drug testing sample contamination prevention and control treatment device proposed in this invention; Figure 11 This is a schematic cross-sectional view of the liquid guide tube of a drug testing sample contamination prevention and control device proposed in this invention.

[0023] Legend: 1. Base plate; 2. Moving plate; 3. L-shaped plate; 4. Fixed plate; 5. Moving assembly; 501. Motor 1; 502. Threaded rod; 503. Threaded block; 504. Slider; 6. Lifting assembly; 601. Sleeve rod; 602. Gear rack; 603. Connecting frame; 604. Gear; 605. Connecting rod; 606. Hand lever; 607. Locking block 1; 608. Spring 1; 609. Ratchet; 610. Locking block 2; 7. 701. Retractable / Unretractable Assembly; 702. Motor II; 703. Trapezoidal Block; 704. Drive Wheel; 705. Belt; 706. Driven Wheel; 707. Bundling Roller; 708. Extraction Pipe; 709. Pump Head; 8. Extrusion Assembly; 801. Motor III; 802. Eccentric Wheel I; 803. Connecting Rod I; 804. Connecting Rod II; 805. Connecting Block I; 806. Push Plate; 807. Discharge Pipe I; 9. Metering Assembly; 901. Connecting... Block 2; 902, Connecting Block 3; 903, Motor 4; 904, Eccentric Wheel 2; 905, Lifting Column; 906, Spring 2; 907, Connecting Column; 908, Moving Rod; 909, Metering Cylinder; 910, Liquid Guide Pipe; 10, Handrail; 11, Support Rod; 12, Casters; 13, Support Frame; 14, Water Pump; 15, Connecting Pipe 1; 16, Inlet Valve; 17, Filter Chamber; 18, Discharge Pipe 2; 19, Filter 20. Plate; 20. Placement assembly; 2001. Placement block; 2002. Sample tube; 2003. Tube cap; 2004. Limiting block; 2005. Spring three; 21. Rotating assembly; 2101. Motor five; 2102. Bevel gear one; 2103. Bevel gear two; 2104. Limiting ring; 2105. Rotating disk; 22. Connecting tube two; 23. Reaction chamber; 24. Connecting tube three; 25. Display panel; 26. Detector. Detailed Implementation

[0024] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0025] Reference Figure 1-11An embodiment of the present invention provides a drug testing sample contamination prevention and control treatment device, comprising a base plate 1, multiple support rods 11, and a support frame 13. An L-shaped plate 3 is fixedly connected to the top of each support rod 11. A moving assembly 5 is provided on the inner wall of the L-shaped plate 3. A moving plate 2 is installed on the left side of the moving assembly 5. A rotating assembly 21 is provided on the inner wall of the L-shaped plate 3. Multiple placement assemblies 20 are provided on the inner wall of the rotating assembly 21. A fixed plate 4 is fixedly connected to the right side of the L-shaped plate 3. A retracting assembly 7 is provided on the top of the fixed plate 4. A lifting assembly 6 is provided on the right side of the inner wall of the base plate 1. The top right side of the L-shaped plate 3... A water pump 14 is fixedly connected. A connecting pipe 15 is fixedly connected to the inner wall of the water pump 14. An inlet valve 16 is fixedly installed through the outer wall of the connecting pipe 15. A filter chamber 17 is fixedly connected to the outer wall of the connecting pipe 15. A filter plate 19 is installed on the inner wall of the filter chamber 17. A liquid outlet pipe 18 is fixedly installed on the inner wall of the filter chamber 17. A reaction chamber 23 is fixedly connected to the outer wall of the liquid outlet pipe 18. A connecting pipe 24 is fixedly connected to the inner wall of the reaction chamber 23. A connecting pipe 22 is fixedly connected to the inner wall of the connecting pipe 24. A metering component 9 is provided at the bottom of the outer wall of the connecting pipe 22. The device includes a compression assembly 8, a display panel 25 fixedly connected to the top front side of the movable plate 2, and a detector 26 fixedly connected to the bottom right side of the movable plate 2. This design is for the upper end of the support rod 11 to fix the inner side of the L-shaped plate 3 to install the movable assembly 5 and the rotating assembly 21 respectively. The movable assembly 5 is connected to the movable plate 2 on the left side, and multiple sets of placement assemblies 20 are installed inside the rotating assembly 21. A fixing plate 4 is fixed to the right side of the L-shaped plate 3, and a take-up and release assembly 7 is set above the fixing plate 4. A lifting assembly 6 is placed on the right side inside the base plate 1, and a water pump 14 is installed on the top right side of the L-shaped plate 3. The water pump 14 is connected in sequence to a connecting pipe 15, an inlet valve 16, and a filter. The device comprises a chamber 17, a filter plate 19, a second outlet pipe 18, a reaction chamber 23, a third connecting pipe 24, a second connecting pipe 22, a quantitative component 9, and a squeezing component 8. A display panel 25 and a detector 26 are installed on the moving plate 2. This device integrates sample extraction, filtration and purification, quantitative distribution, closed transmission, automatic tube replacement, position adjustment, and online detection into one unit. It reduces external contamination and cross-contamination through closed pipelines and structured partitions, and is compatible with sampling from different sized containers and drug pools. It achieves accurate, efficient, and pollution-free pretreatment of drug test samples, solving problems such as poor compatibility, easy contamination, inaccurate quantification, and cumbersome operation of traditional devices.

[0026] The lifting assembly 6 includes a sleeve rod 601, which is fixedly connected to the right side of the inner wall of the base plate 1. A gear 602 is slidably connected to the inner wall of the sleeve rod 601. A connecting frame 603 is fixedly connected to the top of the outer wall of the sleeve rod 601. A gear 604 is installed on the rear side of the inner wall of the connecting frame 603. A connecting rod 605 is fixedly connected to the inner wall of the gear 604. A ratchet 609 is fixedly connected to the left side of the connecting rod 605. A locking block 607 is engaged with the inner wall of the ratchet 609. A locking block 610 is engaged with the inner wall of the ratchet 609. A spring 608 is hung on the outer wall of the locking block 610. A hand lever 606 is installed on the outer wall of the locking block 607. Universal wheels 12 are fixedly connected to the four corners of the bottom of the base plate 1. A handrail 10 is fixedly connected to the left side of the inner wall of the base plate 1. This design allows the lifting assembly 6 to consist of a sleeve rod 601, a gear 602, a connecting frame 603, a gear 604, and a connecting rod 605. The device consists of a connecting rod 605, a hand lever 606, a ratchet 609, a locking block 607, a locking block 610, and a spring 608. A sleeve rod 601 is fixedly installed on the right side of the base plate 1. A toothed rod 602 slides with the sleeve rod 601. A gear 604 meshes with the toothed rod 602 to form a lifting transmission. A connecting rod 605 connects the gear 604 and the ratchet. The locking block and the spring form a one-way self-locking mechanism. Universal wheels 12 are installed at the four corners of the base plate 1. A handrail 10 is set on the left side to facilitate pushing and transferring. The height of the L-shaped plate 3 and the upper mechanism can be adjusted by driving the gear 604 through the hand lever 606. The ratchet self-locking ensures that it will not fall back or slip after positioning. With the universal wheels 12, it can be quickly moved to different inspection positions. It can flexibly adapt to drug containers, reaction tanks and operating tables of different heights, improve sampling flexibility and operational safety, meet the inspection needs of multiple scenarios and heights, and improve the versatility and stability of the device.

[0027] The take-up and take-down assembly 7 includes a second motor 701, which is fixedly connected to the top rear side of the fixed plate 4. Two trapezoidal blocks 702 are fixedly connected to the top front side of the second motor 701. A drive wheel 703 is fixedly connected to the output end of the second motor 701. A belt 704 is fitted on the outer wall of the drive wheel 703, and a driven wheel 705 is fitted on the inner wall of the belt 704. A winding roller 706 is installed on the inner wall of each of the two trapezoidal blocks 702. A suction tube 707 is wound on the outer wall of the winding roller 706, and a pump head 708 is fixedly installed on the outer wall of the suction tube 707. This design allows the take-up and take-down assembly 7 to consist of the second motor 701, trapezoidal blocks 702, drive wheel 703, belt 704, and driven wheel 705. The device consists of a winding roller 706, an extraction tube 707, and a pump head 708. A motor 701 is fixed to the rear of a fixed plate 4. The motor drives the winding roller 706 to rotate synchronously via a drive wheel 703, a belt 704, and a driven wheel 705, enabling the extraction tube 707 to automatically wind up and release. When not in use, the extraction tube 707 is stored and protected to prevent exposure to dust, microorganisms, or residual medications that could cause batch cross-contamination. When in use, the tube can be extended to the required length to reach the bottom of a container or medicine tank for sampling. This keeps the sampling pipeline clean, reduces external contamination, and adapts to extraction needs at different depths and locations, improving the device's contamination control capabilities and sampling adaptability, and ensuring sample purity and reliable test results.

[0028] The rotating assembly 21 includes a motor 2101, which is fixedly connected to the inner wall of the base plate 1. A bevel gear 2102 is fixedly connected to the output end of the motor 2101. A bevel gear 2103 is rotatably connected to the inner wall of the L-shaped plate 3. A rotating disk 2105 is fixedly connected to the outer wall of the bevel gear 2103. A limit ring 2104 is installed on the outer wall of the rotating disk 2105. This design ensures that the rotating assembly 21 consists of the motor 2101, bevel gear 2102, bevel gear 2103, rotating disk 2105, and limit ring 2104. The motor 2101 is fixedly installed on... Inside the base plate 1, the rotating disk 2105 is driven to rotate smoothly through a bevel gear pair. The limiting ring 2104 ensures accurate rotation positioning and no shaking. Multiple placement components 20 are evenly arranged on the rotating disk 2105, which can simultaneously load multiple sample tubes 2002, realize automatic cyclical switching of multiple workstations, and continuously complete sample injection, liquid separation, detection, and material discharge. Automatic rotation replaces the frequent manual replacement of sample tubes 2002, reduces the intensity of operation and the probability of contamination, and improves the efficiency of batch detection. Combined with the closed liquid separation structure, it realizes continuous and automated operation, solving the problems of messy sample placement, easy tipping, and low replacement efficiency in traditional methods.

[0029] The placement assembly 20 includes multiple placement blocks 2001, which are fixedly connected to the inner wall of the rotating disk 2105. Multiple limiting blocks 2004 are slidably connected to the inner wall of each placement block 2001. Multiple springs 2005 are installed on the inner wall of each placement block 2001. A sample tube 2002 is inserted into the inner wall of each placement block 2001, and a tube cap 2003 is snapped onto the top of the outer wall of the sample tube 2002. This design ensures that the placement assembly 20 consists of placement blocks 2001, sample tube 2002, tube cap 2003, limiting blocks 2004, and springs 2005. Inserted into the placement block 2001, spring three 2005 pushes the limiting block 2004 to elastically clamp the sample tube 2002 from multiple directions, which can accommodate sample tubes 2002 of different diameters. It is firmly fixed and not easy to tip over or break. The top of the sample tube 2002 is equipped with a tube cap 2003 to reduce tube opening exposure and external contamination. Insertion and replacement are quick and easy, facilitating rapid replacement and batch management. The orderly layout of multiple workstations, together with the rotating component 21, realizes continuous automatic sampling, reduces manual contact throughout the process, reduces the risk of sample leakage, contamination and loss, improves the standardization of sample management and the safety of the inspection process, and ensures stable and reliable test data.

[0030] The metering component 9 includes a connecting block 3 902, which is fixedly connected to the bottom of the outer wall of the connecting tube 2 22. A connecting block 2 901 is fixedly connected to the bottom of the connecting block 3 902. A motor 4 903 is fixedly connected to the inner wall of the connecting block 2 901. An eccentric wheel 2 904 is fixedly connected to the output end of the motor 4 903. A lifting column 905 is provided on the outer wall of the eccentric wheel 2 904. A moving rod 908 is fixedly connected to the top of the lifting column 905. A spring 2 906 is sleeved on the bottom of the outer wall of the moving rod 908. A metering cylinder 909 is fixedly connected to the top of the moving rod 908. A connecting column 907 is slidably connected to the top of the outer wall of component 908, and a liquid guide tube 910 is fixedly connected to the inner wall of the connecting column 907. This design is for the quantitative component 9, which consists of connecting block 2 901, connecting block 3 902, motor 4 903, eccentric wheel 2 904, lifting column 905, spring 2 906, moving rod 908, quantitative cylinder 909, connecting column 907, and liquid guide tube 910. Motor 4 903 drives eccentric wheel 2 904 to push the lifting column 905 and moving rod 908 up and down, enabling the quantitative cylinder 909 to complete quantitative liquid aspiration and discharge. The liquid guide tube 910 ensures a sealed and unobstructed liquid path. This structure enables high-precision quantitative distribution of samples and reagents, with good quantitative repeatability and small error, avoiding sample waste and excessive reagent addition, reducing testing costs, and improving data consistency. The fully enclosed operation reduces contamination and volatilization, meeting the stringent requirements of precise quantification in pharmaceutical testing, and reducing errors and contamination caused by human operation.

[0031] The extrusion assembly 8 includes a connecting block 1 805, which is fixedly connected to the bottom of a connecting block 2 901. A motor 3 801 is fixedly connected to the right side of the inner wall of the connecting block 1 805. An eccentric wheel 1 802 is fixedly connected to the output end of the motor 3 801. A connecting rod 1 803 is rotatably connected to the outer wall of the eccentric wheel 1 802. A connecting rod 2 804 is rotatably connected to the inner wall of the connecting rod 1 803. A push plate 806 is fixedly connected to the inner wall of the connecting rod 2 804. A liquid outlet pipe 1 807 is installed on the front side of the connecting block 1 805. This design allows the extrusion assembly 8 to consist of a connecting block 1 805, a motor 3 801, an eccentric wheel 1 802, a connecting rod 1 803, a connecting rod 2 804, a push plate 806, and a liquid outlet pipe 1 807. The motor 3 801 drives the eccentric wheel 1 802 and the connecting rod mechanism to drive the push plate 806 to reciprocate, smoothly extruding the quantified sample into the sample tube 2002. With gentle action and uniform liquid dispensing, it avoids air bubbles or sample splashing caused by impact. Combined with the quantitative component 9, it achieves precise liquid dispensing. The entire process is closed and leak-free, reducing the risk of contamination. Its compact structure and stable operation make it suitable for continuous batch testing operations, improving sample processing consistency and testing efficiency, and ensuring accurate and reliable results.

[0032] The moving component 5 includes a motor 501, which is fixedly connected to the top front side of the L-shaped plate 3. A threaded rod 502 is fixedly connected to the output end of the motor 501, and a threaded block 503 is threadedly connected to the outer wall of the threaded rod 502. A slider 504 is fixedly connected to the rear right side of the moving plate 2. This design allows the moving component 5 to consist of the motor 501, threaded rod 502, threaded block 503, and slider 504. The motor 501 drives the threaded rod 502 to rotate, causing the threaded block 503 and the moving plate 2 to move horizontally. The slider 504 provides guidance and support, ensuring smooth operation. The detector 26 and sampling position can be precisely adjusted to achieve horizontal coverage without blind spots, adapting to medicine containers of different diameters and positions, eliminating sampling blind spots. Combined with the lifting component 6, two-dimensional position adjustment is achieved, improving extraction flexibility and sample representativeness, ensuring sufficient and uniform sampling, and improving testing accuracy and device compatibility.

[0033] The rack 602 and gear 604 are meshed together. The connecting rod 605 passes through the inner wall of the connecting frame 603 and is fixedly connected to the inner wall of the gear 604. The spring 608 is hung on the outer wall of the latch block 607. This design ensures stable meshing between the rack 602 and gear 604. The connecting rod 605 passes through the connecting frame 603 and is fixedly connected to the gear 604, ensuring reliable transmission and even force distribution. The spring 608 and the latch block 607 form a ratchet with one-way self-locking, making lifting and adjustment easy and smooth, and ensuring firm positioning without slippage or falling back. The overall mechanical strength is high, and the durability is good. It can withstand long-term frequent adjustments without failure. It is suitable for continuous operation scenarios in inspection agencies, improving the stability of height adjustment and the service life of the device, providing reliable support for flexible sampling in multiple scenarios, and ensuring operational safety and stable operation.

[0034] The connecting column 907 is fixedly connected to the top of the inner wall of the connecting block 2 901. The liquid guide tube 910 passes through the inner wall of the connecting block 2 901. The quantitative cylinder 909 is set on the inner wall of the connecting block 3 902. This design allows the connecting column 907 to be fixed to the top of the inner wall of the connecting block 2 901, the liquid guide tube 910 to pass through the connecting block 2 901, and the quantitative cylinder 909 to be installed inside the connecting block 3 902. The pipeline routing is reasonable, the sealing is tight, there is no liquid accumulation, no leakage, and no dead corners. The quantitative cylinder 909 has a regular movement space, and the lifting and lowering are smooth and unobstructed, ensuring accurate and stable quantitative action, stable sample and reagent transfer, reducing the risk of cross-contamination, high structural integration, and simple maintenance. It effectively improves the quantitative control accuracy and the reliability of device operation, ensures accurate and reliable test data, and meets the high cleanliness and high precision requirements of drug testing.

[0035] Working principle: Before starting the drug control and processing device, the sample tube 2002 is inserted into the placement block 2001 of the placement component 20. The spring 3 2005 pushes the limiting block 2004 to automatically clamp the sample tube 2002, and the tube cap 2003 seals to reduce contamination. The device is moved to the sampling position by the handle 10 and the universal wheel 12. The lever 606 of the lifting component 6 is operated to drive the gear 604 and the rack 602 to mesh and adjust the L-shaped plate and the upper mechanism to a suitable height. The ratchet 609, the locking block and the spring 1 608 form a self-locking mechanism to ensure that the height is stable and does not fall back. The moving component 5 is started, and the motor 1 501 drives the threaded rod 502 to rotate, which drives the threaded block 503 and the moving plate 2 to move horizontally, aligning the detector 26 and the sampling mechanism with the target sampling point, realizing horizontal and vertical positioning, adapting to drug containers of different diameters and volumes and open reaction pools, eliminating sampling dead angles, and ensuring that the sample is fully extracted and representative.

[0036] During sampling, the motor 701 of the take-up and release assembly 7 starts, driving the winding roller 706 to rotate via the drive wheel 703, belt 704, and driven wheel 705, releasing the extraction tube 707 into the liquid. The pump head 708, in conjunction with the water pump 14, generates negative pressure, drawing the drug sample into the pipeline through the extraction tube 707. The sample then flows sequentially through the connecting pipe 15 and the inlet valve 16 into the filter chamber 17. The filter plate 19 in the filter chamber 17 pre-treats the sample, removing particulate impurities and potential contaminants, reducing interference, and protecting subsequent pipelines and devices, thus purifying the sample. The purified sample then enters the outlet pipe 18. The sample enters the reaction chamber 23, where necessary pretreatment or mixing with the detection reagent can be completed to prepare for detection. The reacted liquid enters the quantitative component 9 through the connecting tube 3 24 and the connecting tube 2 22. The motor 4 903 drives the eccentric wheel 2 904 to rotate, which in turn drives the lifting column 905, the moving rod 908 and the quantitative cylinder 909 to move up and down. The quantitative cylinder 909 completes quantitative liquid aspiration and discharge during the lifting process, realizing high-precision quantitative distribution of sample and detection reagent, avoiding sample waste and reagent overdose, ensuring that the sample volume and dosage are consistent each time, and improving the repeatability and reliability of test data.

[0037] After quantitative sampling is completed, the motor 801 of the squeezing assembly 8 starts, driving the eccentric wheel 802, connecting rod 803 and connecting rod 804 to move, driving the push plate 806 to smoothly squeeze the liquid path, and accurately injecting the quantitative sample into the sample tube 2002 below through the liquid outlet tube 807. The motor 2101 of the rotating assembly 21 works synchronously, and through the meshing transmission of bevel gear 2102 and bevel gear 2103, it drives the rotating disk 2105 and the placement assembly 20 to rotate at a uniform speed, sending the empty sample tubes 2002 to the liquid dispensing position in sequence, realizing continuous, automatic and batch sampling, eliminating the need for frequent manual replacement of sample tubes 2002, greatly improving the detection efficiency, and avoiding contamination caused by manual contact. After receiving the sample, the sample tube 2002 continues to be moved with the rotating disk 2105, and can be capped, transferred or tested online in sequence. The detector 26 on the moving plate 2 performs real-time detection on the sample, and the detection data is displayed intuitively by the display panel 25, which is convenient for operators to record and judge.

[0038] After sampling, motor 2 701 reverses to drive the winding roller 706 to retract the extraction tube 707, returning the pipeline to its original position for safekeeping. This prevents exposed contamination and drug residue, reducing the risk of cross-contamination between batches. The entire sampling, transmission, filtration, quantification, reaction, and detection process is completed within a closed pipeline and structured components, maximizing the isolation from airborne dust, human contact, and cross-contamination of equipment. This achieves full-process contamination control from sampling to detection. The lifting component 6, moving component 5, rotating component 21, quantitative component 9, and extrusion component 8 are all driven by motor 1 501, motor 2 701, motor 3 801, motor 4 903, and motor 5 2101. With the help of self-locking and guiding structures, the operation is stable, the positioning is accurate, and the operation is simple, reducing manual labor and operational errors.

[0039] The drug control and processing device integrates lifting components 6, moving components 5, rotating components 21, quantitative components 9, squeezing components 8, tube replacement, online detection, and contamination control functions. Its compact structure and strong adaptability meet the needs of various scenarios, including pharmaceutical manufacturers, testing institutions, and medical institutions. It is suitable for testing various liquid drug samples such as injections, oral liquids, and traditional Chinese medicine extracts. It solves the problems of poor compatibility, susceptibility to contamination, inaccurate quantification, low efficiency, and inconvenient operation associated with traditional equipment, improving the authenticity, accuracy, and reliability of drug testing results and ensuring drug quality and medication safety.

[0040] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A device for preventing and controlling contamination of drug testing samples, comprising a base plate (1), multiple support rods (11), and a support frame (13), characterized in that: An L-shaped plate (3) is fixedly connected to the top of the support rod (11). A moving component (5) is provided on the inner wall of the L-shaped plate (3). A moving plate (2) is installed on the left side of the moving component (5). A rotating component (21) is provided on the inner wall of the L-shaped plate (3). Multiple placement components (20) are provided on the inner wall of the rotating component (21). A fixed plate (4) is fixedly connected to the right side of the L-shaped plate (3). A retraction component (7) is provided on the top of the fixed plate (4). A lifting component (6) is provided on the right side of the inner wall of the base plate (1). A water pump (14) is fixedly connected to the top right side of the L-shaped plate (3). A connecting pipe (15) is fixedly connected to the inner wall of the water pump (14). An inlet valve is fixedly installed through the outer wall of the connecting pipe (15). (16) A filter chamber (17) is fixedly connected to the outer wall of the first connecting pipe (15). A filter plate (19) is installed on the inner wall of the filter chamber (17). An outlet pipe (18) is fixedly installed on the inner wall of the filter chamber (17). A reaction chamber (23) is fixedly connected to the outer wall of the outlet pipe (18). A third connecting pipe (24) is fixedly connected to the inner wall of the reaction chamber (23). A second connecting pipe (22) is fixedly connected to the inner wall of the third connecting pipe (24). A quantitative component (9) is provided at the bottom of the outer wall of the second connecting pipe (22). A squeezing component (8) is provided at the bottom of the quantitative component (9). A display panel (25) is fixedly connected to the top front side of the moving plate (2). A detector (26) is fixedly connected to the bottom right side of the moving plate (2).

2. The drug testing sample contamination prevention and treatment device according to claim 1, characterized in that: The lifting assembly (6) includes a sleeve rod (601), which is fixedly connected to the right side of the inner wall of the base plate (1). A toothed rod (602) is slidably connected to the inner wall of the sleeve rod (601). A connecting frame (603) is fixedly connected to the top of the outer wall of the sleeve rod (601). A gear (604) is installed on the rear side of the inner wall of the connecting frame (603). A connecting rod (605) is fixedly connected to the inner wall of the gear (604). The left side of the connecting rod (605) A ratchet (609) is fixedly connected to the side. A locking block 1 (607) is engaged with the inner wall of the ratchet (609). A locking block 2 (610) is engaged with the inner wall of the ratchet (609). A spring 1 (608) is hung on the outer wall of the locking block 2 (610). A handle (606) is installed on the outer wall of the locking block 1 (607). Universal wheels (12) are fixedly connected to the four corners of the bottom of the base plate (1). A handrail (10) is fixedly connected to the left side of the inner wall of the base plate (1).

3. The drug testing sample contamination prevention and treatment device according to claim 1, characterized in that: The take-up and release assembly (7) includes a second motor (701), which is fixedly connected to the top rear side of the fixed plate (4). Two trapezoidal blocks (702) are fixedly connected to the top front side of the second motor (701). A drive wheel (703) is fixedly connected to the output end of the second motor (701). A belt (704) is sleeved on the outer wall of the drive wheel (703). A driven wheel (705) is sleeved on the inner wall of the belt (704). A winding roller (706) is installed on the inner wall of each of the two trapezoidal blocks (702). An extraction tube (707) is wound on the outer wall of the winding roller (706). A pump head (708) is fixedly installed on the outer wall of the extraction tube (707).

4. The drug testing sample contamination prevention and treatment device according to claim 1, characterized in that: The rotating assembly (21) includes a motor five (2101), which is fixedly connected to the inner wall of the base plate (1). The output end of the motor five (2101) is fixedly connected to a bevel gear one (2102). The inner wall of the L-shaped plate (3) is rotatably connected to a bevel gear two (2103). The outer wall of the bevel gear two (2103) is fixedly connected to a rotating disk (2105). A limit ring (2104) is installed on the outer wall of the rotating disk (2105).

5. The drug testing sample contamination prevention and treatment device according to claim 1, characterized in that: The placement assembly (20) includes multiple placement blocks (2001), which are fixedly connected to the inner wall of the rotating disk (2105). Multiple limiting blocks (2004) are slidably connected to the inner wall of the placement block (2001). Multiple springs (2005) are installed on the inner wall of the placement block (2001). A sample tube (2002) is inserted into the inner wall of the placement block (2001), and a tube cap (2003) is snapped onto the top of the outer wall of the sample tube (2002).

6. The drug testing sample contamination prevention and treatment device according to claim 1, characterized in that: The quantitative component (9) includes a connecting block three (902), which is fixedly connected to the bottom of the outer wall of the connecting tube two (22). The bottom of the connecting block three (902) is fixedly connected to the connecting block two (901). The inner wall of the connecting block two (901) is fixedly connected to the motor four (903). The output end of the motor four (903) is fixedly connected to the eccentric wheel two (904). The outer wall of the eccentric wheel two (904) is provided with a lifting column (905). The top of the lifting column (905) is fixedly connected to a moving rod (908). The bottom of the outer wall of the moving rod (908) is fitted with a spring two (906). The top of the moving rod (908) is fixedly connected to a quantitative cylinder (909). The top of the outer wall of the moving rod (908) is slidably connected to a connecting column (907). The inner wall of the connecting column (907) is fixedly connected to a liquid guide tube (910).

7. The drug testing sample contamination prevention and treatment device according to claim 1, characterized in that: The extrusion assembly (8) includes a connecting block one (805), which is fixedly connected to the bottom of a connecting block two (901). A motor three (801) is fixedly connected to the right side of the inner wall of the connecting block one (805). An eccentric wheel one (802) is fixedly connected to the output end of the motor three (801). A connecting rod one (803) is rotatably connected to the outer wall of the eccentric wheel one (802). A connecting rod two (804) is rotatably connected to the inner wall of the connecting rod one (803). A push plate (806) is fixedly connected to the inner wall of the connecting rod two (804). A liquid outlet pipe one (807) is installed on the front side of the connecting block one (805).

8. The drug testing sample contamination prevention and treatment device according to claim 1, characterized in that: The moving component (5) includes a motor (501), which is fixedly connected to the top front side of the L-shaped plate (3). The output end of the motor (501) is fixedly connected to a threaded rod (502), and the outer wall of the threaded rod (502) is threadedly connected to a threaded block (503). The right rear end of the moving plate (2) is fixedly connected to a slider (504).

9. The drug testing sample contamination prevention and treatment device according to claim 2, characterized in that: The rack (602) and the gear (604) are meshed together. The connecting rod (605) passes through the inner wall of the connecting frame (603) and is fixedly connected to the inner wall of the gear (604). The spring (608) is hung on the outer wall of the locking block (607).

10. A drug testing sample contamination prevention and treatment device according to claim 6, characterized in that: The connecting column (907) is fixedly connected to the top of the inner wall of the connecting block two (901), the liquid guide tube (910) passes through the inner wall of the connecting block two (901), and the metering cylinder (909) is set on the inner wall of the connecting block three (902).

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