Automatic radio-pharmaceutical dispensing device

Abstract

This invention relates to the field of radiopharmaceutical dispensing technology, specifically to an automated radiopharmaceutical dispensing device, including a dispensing cabinet. The dispensing cabinet is horizontally divided into a dispensing area and a temporary storage area. The device further includes: a first linear actuator disposed along the length of the dispensing cabinet in the dispensing area; a robotic arm mounted on the first linear actuator, the first linear actuator driving the robotic arm to move along the length of the dispensing cabinet, the robotic arm gripping a syringe to dispense the drug, the syringe being coated with a lead layer; and a stock solution storage module, having multiple modules arranged parallel to the length of the first linear actuator in the dispensing area, the upper part of the stock solution storage module having an opening that can be opened or closed, and a stock solution bottle for storing radiopharmaceutical stock solution located directly below the opening. This invention reduces radiation exposure for medical personnel during handling and use.

Description

Technical Field

[0001] This invention relates to the field of radiopharmaceutical dispensing technology, specifically to an automated radiopharmaceutical dispensing device. Background Technology

[0002] When treating patients, some patients need to receive radiopharmaceutical therapy. Before treatment, medical staff need to use a syringe to extract a certain amount of drug solution from the radiopharmaceutical source solution for use in the treatment. However, the extraction process must be strictly followed, otherwise the patient may be harmed by radioactive substances. In order to overcome the above problems, existing technologies have also designed systems that can automatically dispense radiopharmaceuticals.

[0003] For example, Chinese Patent Publication No. CN114796719B discloses an automatic radiopharmaceutical dispensing system, comprising: a drug source for providing radiopharmaceuticals; a fixing frame for temporarily fixing a syringe consisting of an injection body and a cap, the fixing frame including a frame body, one side of which is provided with a lower locking component for limiting the cap and an upper locking component for limiting the injection body, wherein the injection body on the fixing frame can detach from the cap and be removed from the fixing frame in a first direction, and the injection body and the cap can be removed from the fixing frame simultaneously in a second direction, the first direction and the second direction being perpendicular, and the first direction being the length direction of the injection body; an activity measuring mechanism, the activity measuring mechanism including an activity meter, a measuring frame and a lifting assembly, the activity meter having a well-directed measuring channel, the measuring frame being positioned in the direction of the well-directed measuring channel and capable of carrying a syringe or injection body, the lifting assembly being capable of driving the measuring frame to rise and fall, so that the syringe or injection body carried thereon can enter and exit the well-directed measuring channel.

[0004] While the aforementioned solution enables automated dispensing of radiopharmaceuticals, avoiding the direct radiation risk associated with manual drug extraction by medical personnel, significant safety hazards remain during the actual dispensing process. Firstly, the radiopharmaceutical source solution lacks an effective sealed protective structure during dispensing, remaining directly exposed to the outside air. The ionizing radiation it releases continues to diffuse into the operating environment, contaminating surrounding medical equipment and creating a long-term radiation environment. Secondly, the syringes used in the existing system are conventional medical syringes without dedicated radiation shielding layers, failing to prevent radiation penetration by the radiopharmaceutical solution. The syringes themselves remain radioactive after dispensing. More critically, the operating area of ​​the existing automated dispensing system lacks a sealed radiation shielding chamber, directly connecting to the external environment. Medical personnel must approach the operating area when retrieving the dispensed syringes, directly exposing themselves to secondary radiation from the source solution exposure and syringe radiation. From a clinical perspective, medical staff who are engaged in radiopharmaceutical packaging work for a long time may suffer irreversible damage to organs such as the hematopoietic system and thyroid gland even from low-dose cumulative radiation, seriously threatening their health. This also does not comply with the safety protection standards for radiopharmaceutical handling. Summary of the Invention

[0005] To address the aforementioned issues, an automated radiopharmaceutical dispensing device is provided. This device utilizes a dispensing cabinet divided into a dispensing area and a temporary storage area. It is equipped with a first linear actuator positioned along the length of the cabinet, a robotic arm that moves under its drive, and multiple parallel-arranged stock solution storage modules. This achieves automated dispensing of radiopharmaceuticals, eliminating the need for manual handling and transfer by medical personnel and avoiding the risk of direct radiation exposure. The robotic arm's operating area covers both areas, ensuring smooth handling and transfer. The multiple stock solution storage modules can store different drugs in different categories. The syringes are coated with a lead layer to effectively block radiation penetration, reducing radiation damage during handling and use by medical personnel.

[0006] To address the problems of the prior art, the present invention provides an automated radiopharmaceutical dispensing device, including a dispensing cabinet;

[0007] The repackaging cabinet is horizontally divided into a repackaging area and a temporary storage area. The repackaging device also includes:

[0008] A first linear actuator is disposed in the dispensing area along the length of the dispensing cabinet;

[0009] A robotic arm is mounted on a first linear actuator, which drives the robotic arm to move along the length of the dispensing cabinet. The operating area formed by the robotic arm under the drive of the first linear actuator covers the dispensing area and the temporary storage area. The robotic arm is used to grip a syringe to pick up medicine. The syringe is covered with a lead layer.

[0010] The raw material storage module has multiple components arranged in the dispensing area parallel to the length direction of the first linear actuator. The upper part of the raw material storage module is provided with an opening that can be opened or closed, and a raw material bottle for storing radiopharmaceutical source solution is located directly below the opening.

[0011] Preferably, the stock solution storage module is further provided with:

[0012] A baffle is movably positioned below the opening; when the baffle is moved to the position directly below the opening, the opening closes.

[0013] The drive unit, located on one side of the moving plate, is used to drive the baffle plate to move.

[0014] Preferably, both the shield and the outer casing of the original liquid storage module are made of lead.

[0015] Preferably, the stock solution storage module is further provided with:

[0016] The lifting frame is vertically movable and positioned below the baffle plate, and the original liquid bottle is positioned on the upper surface of the lifting frame.

[0017] Preferably, a stopper is fixedly provided at the lower part of the shield, and the stopper can cover the upper part of the original liquid bottle.

[0018] Preferably, the side wall of the stock solution storage module is provided with an exhaust port, and the side wall of the dispensing area is provided with a fan to introduce filtered outside air into the dispensing area.

[0019] Preferably, the outer side of the stock solution storage module is provided with a radioactive material filter that communicates with the exhaust port.

[0020] Preferably, a partition that moves vertically between the dispensing area and the temporary storage area is provided, and the partition can separate the dispensing area and the temporary storage area into two independent regions.

[0021] Preferably, a transparent observation window is also provided on the side wall of the dispensing area.

[0022] Preferably, the temporary storage area is provided with a rack for placing the syringe.

[0023] The advantages of this invention compared to the prior art are:

[0024] 1. This invention achieves automated dispensing of radiopharmaceuticals by setting up a dispensing cabinet and dividing its interior into a dispensing area and a temporary storage area, coupled with a first linear actuator positioned along the length of the dispensing cabinet, a robotic arm that can move under its drive, and multiple parallel-arranged stock solution storage modules. This eliminates the need for medical personnel to manually handle and transfer the drugs, thus avoiding the risk of direct exposure to radiation. The robotic arm's operating area covers both areas, ensuring smooth handling and transfer. The multiple stock solution storage modules can store different drugs in different categories. The syringes are coated with a lead layer to effectively block radiation penetration, reducing radiation damage to medical personnel during handling and use, complying with safety protection regulations, and improving dispensing efficiency and standardization.

[0025] 2. By setting up a lead shield and the outer shell of the raw material storage module, along with the shield's drive unit and the raw material bottle sealing plug, and the coordinated action of the lifting frame and the second linear actuator, the raw material storage is fully sealed and protected, avoiding exposure and volatilization of radioactive drug raw materials, reducing radiation diffusion, and preventing radiation interference between different drugs, thus ensuring efficacy. This solves the core problems of insufficient raw material protection and continuous radiation diffusion in existing technologies, further improving the radiation protection level of the device and meeting safe operation specifications.

[0026] 3. Through the coordinated operation of fans, exhaust ports, and radioactive material filters, combined with the partitioned isolation design of liftable partitions, a complete airflow filtration and area protection system is formed. This system can prevent the volatilization and diffusion of radioactive drugs during liquid extraction, purify the exhaust airflow to avoid polluting the external environment, and effectively isolate the dispensing area from the temporary storage area to prevent cross-contamination of radiation. It balances cleanliness and safety, further improving the overall protection performance of the device. Attached Figure Description

[0027] Figure 1 This is a three-dimensional schematic diagram of an automatic radiopharmaceutical dispensing device according to the present invention.

[0028] Figure 2 This is a partially cross-sectional three-dimensional schematic diagram of an automatic radiopharmaceutical dispensing device according to the present invention.

[0029] Figure 3 This invention relates to an automated radiopharmaceutical dispensing device. Figure 2 A cross-sectional view at point A in the middle.

[0030] Figure 4 This is a side view of an automated radiopharmaceutical dispensing device according to the present invention.

[0031] Figure 5 This invention relates to an automated radiopharmaceutical dispensing device. Figure 4 Schematic diagram of cross-section at point BB.

[0032] Figure 6This is a cross-sectional three-dimensional schematic diagram of an automated radiopharmaceutical dispensing device according to the present invention. Figure 1 .

[0033] Figure 7 This is a cross-sectional three-dimensional schematic diagram of an automated radiopharmaceutical dispensing device according to the present invention. Figure 2 .

[0034] Figure 8 This is a partially cross-sectional three-dimensional schematic diagram of the stock solution storage module in an automatic radiopharmaceutical dispensing device of the present invention.

[0035] Figure 9 This is a three-dimensional schematic diagram of the original liquid storage module in an automatic radiopharmaceutical dispensing device of the present invention after the outer shell portion has been removed.

[0036] The diagram is labeled as follows: 1. Packaging cabinet; 11. Packaging area; 12. Temporary storage area; 13. Fan; 14. Partition; 15. Transparent observation window; 16. Placement rack; 2. First linear actuator; 3. Robotic arm; 4. Original solution storage module; 41. Opening; 42. Original solution bottle; 43. Baffle plate; 431. Plug; 44. Drive unit; 441. First gear; 442. Second gear; 443. Rotary actuator; 45. Lifting frame; 46. Second linear actuator; 47. Exhaust port; 5. Syringe; 6. Radioactive material filter. Detailed Implementation

[0037] To further understand the features, technical means, and specific objectives and functions achieved by the present invention, the present invention will be described in further detail below with reference to the accompanying drawings and specific embodiments.

[0038] Reference Figures 1 to 8 An automated dispensing device for radiopharmaceuticals, comprising a dispensing cabinet 1;

[0039] The dispensing cabinet 1 is horizontally divided into a dispensing area 11 and a temporary storage area 12. The dispensing device also includes:

[0040] The first linear actuator 2 is disposed in the dispensing area 11 along the length direction of the dispensing cabinet 1;

[0041] A robotic arm 3 is mounted on a first linear actuator 2. The first linear actuator 2 is used to drive the robotic arm 3 to move along the length direction of the dispensing cabinet 1. The operating area formed by the robotic arm 3 under the drive of the first linear actuator 2 covers the dispensing area 11 and the temporary storage area 12. The robotic arm 3 is used to hold the syringe 5 to pick up the medicine. The syringe 5 is covered with a lead layer.

[0042] The stock solution storage module 4 has multiple components arranged in the dispensing area 11 parallel to the length direction of the first linear actuator 2. The upper part of the stock solution storage module 4 is provided with an opening 41 that can be opened or closed, and a stock solution bottle 42 for storing radiopharmaceutical stock solution is located directly below the opening 41.

[0043] When the automated radiopharmaceutical dispensing device is in operation, the syringe 5 is first placed in the temporary storage area 12. Then, the first linear actuator 2 is activated, driving the robotic arm 3 to move along the length of the dispensing cabinet 1, allowing the robotic arm 3 to enter the temporary storage area 12 and grip the syringe 5. After gripping, the first linear actuator 2 drives the robotic arm 3 to move along the length of the dispensing cabinet 1 to the side of the corresponding stock solution storage module 4 in the dispensing area 11. At this time, the opening 41 on the upper part of the stock solution storage module 4 opens, and the robotic arm 3, gripping the syringe 5 with an outer lead coating, takes the drug solution from the opened opening 41. After taking the solution, the first linear actuator 2 drives the robotic arm 3 to move along the length of the dispensing cabinet 1 again, transferring the syringe 5 back to the temporary storage area 12, completing one dispensing operation. The above operation can be repeated to achieve continuous dispensing of multiple syringes 5. Moreover, driven by the first linear actuator 2, the operating area of ​​the robotic arm 3 can cover the entire dispensing area 11 and the temporary storage area 12, ensuring the smooth progress of the dispensing process.

[0044] By setting up a dispensing cabinet 1 and dividing its interior into a dispensing area 11 and a temporary storage area 12, the dispensing operation and the storage of syringes 5 are separated, reducing the spread of radiopharmaceutical radiation. The first linear actuator 2 drives the robotic arm 3 to move along the length of the dispensing cabinet 1, and the robotic arm 3's operating area covers both the dispensing area 11 and the temporary storage area 12. Throughout the process, medical personnel do not need to manually extract the drug solution or transfer the syringes 5, avoiding the risk of direct contact with the radiopharmaceutical source solution and preventing radiation damage that may result from manual operation. Multiple raw material storage modules 4 are arranged parallel to the length of the first linear actuator 2, enabling the classified storage and dispensing of different radiopharmaceuticals, improving dispensing efficiency and facilitating standardized management. The syringes 5 are externally coated with a lead layer, effectively blocking radiation penetration of the radiopharmaceutical solution inside the syringes 5, reducing the radiation risk posed by the syringes 5 themselves after dispensing, and minimizing the radiation impact on medical personnel during handling and use of the syringes 5, protecting their health and complying with safety protection regulations for radiopharmaceutical handling. In addition, the upper part of the original liquid storage module 4 is provided with an opening 41 that can be opened or closed. It can be opened when taking liquid and closed after taking liquid, which reduces the time that the radiopharmaceutical source liquid is exposed to the outside air, reduces the possibility of radiation diffusion and drug volatilization, further improves the safety of the dispensing process, and can also ensure the efficacy of radiopharmaceutical to a certain extent.

[0045] Reference Figure 8 and Figure 9The original solution storage module 4 is also equipped with:

[0046] A baffle plate 43 is movably positioned below the opening 41. When the baffle plate 43 moves to directly below the opening 41, the opening 41 closes.

[0047] The drive unit 44 is located on one side of the movable plate and is used to drive the baffle plate 43 to move.

[0048] The drive unit 44 includes a first gear 441, a second gear 442, and a rotary driver 443. The baffle plate 43 has a fan-shaped structure. The first gear 441 is fixedly installed at the center of the baffle plate 43, and the second gear 442 is installed on one side of the first gear 441. The first gear 441 and the second gear 442 mesh with each other. The output end of the rotary driver 443 is fixedly connected to the second gear 442. The rotary driver 443 drives the first gear 441 to rotate through the second gear 442, thereby causing the baffle plate 43 to rotate. The baffle plate 43 achieves the blocking and opening of the opening 41 by rotating, thereby enabling the opening 41 to open or close.

[0049] During the dispensing of radiopharmaceuticals, when the robotic arm 3 moves the syringe 5 to the side of the corresponding original solution storage module 4 to prepare for liquid retrieval, the drive unit 44 starts working. The rotary driver 443 starts and drives the second gear 442 to rotate. Since the first gear 441 and the second gear 442 mesh with each other, the rotation of the second gear 442 will drive the first gear 441 to rotate synchronously. The first gear 441 is fixed at the center of the fan-shaped shield 43, which in turn drives the shield 43 to rotate, so that the shield 43 moves out from directly below the opening 41, opening the opening 41. This makes it easier for the robotic arm 3 to grip the syringe 5, descend, and pass through the opening 41 to retrieve the liquid. After the liquid retrieval is completed, the robotic arm 3 drives the syringe 5 to rise, and the rotary driver 443 starts in the reverse direction. Through the second gear 442, the first gear 441 is driven to rotate in the reverse direction, driving the shield 43 to rotate directly below the opening 41 and closing the opening 41.

[0050] The opening 41 is opened and closed by driving the baffle plate 43 to rotate through the drive unit 44. The opening 41 can be closed in time after liquid extraction, avoiding prolonged exposure of the radiopharmaceutical source liquid in the dispensing area 11, reducing radiation diffusion and drug volatilization, solving the radiation pollution problem caused by the exposure of the original liquid in the prior art, and improving the safety of the dispensing process. At the same time, the fan-shaped baffle plate 43 and the gear transmission structure can achieve precise opening and closing of the opening 41, ensuring the smoothness of the liquid extraction process.

[0051] Reference Figures 1 to 9 Both the shielding plate 43 and the outer casing of the original liquid storage module 4 are made of lead.

[0052] Both the shielding plate 43 and the outer shell of the raw material storage module 4 are made of lead. During operation, the outer shell of the raw material storage module 4 provides all-around radiation shielding for the stored radiopharmaceutical raw materials, preventing ionizing radiation released by the radiopharmaceuticals from penetrating the outer shell and spreading to the dispensing area 11 and even the external environment. When the opening 41 is closed, the shielding plate 43 acts as a shielding structure at the opening 41, forming a complete shield with the outer shell, further preventing radiation leakage from the opening 41. The technical advantage of this structure lies in the excellent radiation shielding performance of lead. By using lead for both the shielding plate 43 and the outer shell of the raw material storage module 4, the problem of insufficient effective sealing protection and continuous radiation diffusion in the raw material dispensing process in existing technologies is effectively solved. This avoids the potential for radiation contamination of surrounding medical equipment and the formation of a long-term radiation environment. At the same time, it also reduces the radiation interaction between radiopharmaceuticals in different raw material storage modules 4, ensuring the efficacy of each drug and further improving the radiation protection capability of the device, complying with the safety protection specifications for radiopharmaceutical operations.

[0053] Reference Figures 6 to 8 The original solution storage module 4 is also equipped with:

[0054] The lifting frame 45 is vertically movable and positioned below the baffle plate 43, and the original liquid bottle 42 is positioned on the upper end face of the lifting frame 45.

[0055] A second linear drive 46 for driving the movement of the lifting frame 45 is provided on one side of the lifting frame 45.

[0056] Before the liquid extraction operation, when it is necessary to open the opening 41 of the stock solution storage module 4, the second linear actuator 46 is activated first, driving the lifting frame 45 to descend vertically. The stock solution bottle 42 on the upper surface of the lifting frame 45 descends synchronously with the lifting frame 45, so that the upper part of the stock solution bottle 42 separates from the bottom of the baffle plate 43 at the opening 41, avoiding interference between the baffle plate 43 and the stock solution bottle 42 when it rotates. After the baffle plate 43 rotates out and the opening 41 is fully opened, the second linear actuator 46 drives the lifting frame 45 to descend vertically. The machine moves upward in a straight line, causing the original liquid bottle 42 to rise to a preset height. When the original liquid bottle 42 reaches the preset height, there is a gap between the upper part of the original liquid bottle 42 and the opening 41. Then, the robot arm 3 holds the syringe 5 and passes it through the opening 41 to enter the original liquid bottle 42 to extract the liquid. After the liquid extraction is completed, the second linear actuator 46 drives the lifting frame 45 to descend. Then, the baffle plate 43 rotates to close the opening 41. The second linear actuator 46 drives the original liquid bottle 42 to rise and reset, so that the upper part of the original liquid bottle 42 contacts the bottom of the baffle plate 43.

[0057] The lifting frame 45 is driven to rise and fall by the second linear actuator 46, thereby realizing the adjustment of the height of the original liquid bottle 42. This solves the problem of interference between the rotation of the baffle 43 and the original liquid bottle 42, ensuring that the baffle 43 can smoothly open and close the opening 41. At the same time, the height of the original liquid bottle 42 can be adjusted according to the liquid extraction needs of the syringe 5, making the liquid extraction process smoother and avoiding problems such as insufficient liquid extraction or collision damage between the syringe 5 and the original liquid bottle 42 due to the fixed position of the original liquid bottle 42. This further improves the stability and reliability of the dispensing operation, and also reduces the volatilization of radioactive drugs and radiation leakage during the liquid extraction process.

[0058] It is worth noting that a display screen is installed on the side wall of the dispensing device, and the aforementioned preset positions and related data can be input into the display screen in advance and automatically controlled by the program.

[0059] Reference Figure 9 A stopper 431 is fixedly provided at the lower part of the shielding plate 43, and the stopper 431 can cover the upper part of the original liquid bottle 42.

[0060] When the device is not dispensing, the baffle plate 43 is located directly below the opening 41. At this time, the stopper 431 at the bottom of the baffle plate 43 covers the upper part of the original liquid bottle 42, sealing the liquid outlet of the original liquid bottle 42. When liquid dispensing is required, the second linear actuator 46 drives the lifting frame 45 to descend, which in turn lowers the original liquid bottle 42, separating the liquid outlet of the original liquid bottle 42 from the stopper 431. Then, the baffle plate 43 rotates under the drive of the drive unit 44, opening the opening 41, and the lifting frame 45 rises to the preset height. After liquid dispensing is completed, the baffle plate 43 rotates back to directly below the opening 41, and the second linear actuator 46 drives the lifting frame 45 to rise, which in turn raises the original liquid bottle 42, so that the stopper 431 covers the liquid outlet of the original liquid bottle 42 again, achieving the sealing of the original liquid bottle 42. By setting a stopper 431 at the lower part of the baffle plate 43, the original liquid bottle 42 can be sealed when not in liquid extraction mode, avoiding the problem of radioactive drug volatilization, further reducing the amount of radioactive drug volatilization during storage and placement, reducing the risk of radiation diffusion, and preventing external impurities from entering the original liquid bottle 42 and contaminating the drug solution, thus ensuring the efficacy of the radioactive drug. Combined with the lifting action of the lifting frame 45, the stopper 431 can be accurately closed and separated from the liquid extraction port of the original liquid bottle 42 without affecting normal liquid extraction operation, further improving the sealing and safety of the device.

[0061] Reference Figure 5 The original liquid storage module 4 is provided with an exhaust port 47 on its side wall, and the dispensing area 11 is provided with a fan 13 on its side wall to introduce filtered outside air into the dispensing area 11.

[0062] When the liquid is taken out, the fan 13 starts when the opening 41 of the raw liquid storage module 4 is opened, and the filtered air from the outside is introduced into the dispensing area 11. The introduced air forms an airflow in the dispensing area 11, flows from top to bottom through the opening 41 into the interior of the raw liquid storage module 4, and is then discharged through the exhaust port 47 on the side wall of the raw liquid storage module 4, forming a stable airflow circulation. The introduction of filtered air by the fan 13 to form a top-down airflow effectively prevents the volatilization of radioactive drugs during the liquid extraction process, avoiding the intrusion of volatilized radioactive drugs into the dispensing area 11 and their diffusion into the external environment. This solves the radiation pollution problem caused by the volatilization of the original liquid in the prior art. At the same time, the filtered air can prevent external impurities from entering the original liquid storage module 4 and the dispensing area 11, ensuring the cleanliness of the liquid and the dispensing environment and preventing the liquid from being contaminated. When the airflow passes over the original liquid bottle 42, it can also blow the residual liquid attached to the outside of the syringe 5 back into the original liquid bottle 42, reducing liquid waste and avoiding additional radiation from the residual liquid, further improving the safety and economy of the dispensing process.

[0063] Reference Figure 6 and Figure 7 The outer side of the original liquid storage module 4 is provided with a radioactive material filter 6 that is connected to the exhaust port 47.

[0064] When the fan 13 is operating and the airflow exits the raw material storage module 4 through the exhaust port 47, the airflow first enters the radioactive material filter 6 connected to the exhaust port 47. The radioactive material filter 6 filters and adsorbs the radioactive volatiles contained in the airflow, trapping the radioactive materials. The filtered clean air is then discharged to the external environment. By setting up the radioactive material filter 6, the diffusion path of radioactive materials is blocked, avoiding secondary harm to the surrounding environment and medical personnel from radiation. At the same time, the filter can effectively trap radioactive materials in the airflow, preventing them from contaminating the outside air and medical equipment, meeting the environmental protection and safety protection requirements for radiopharmaceutical operations, further improving the overall protection performance of the device, and ensuring that the entire dispensing process complies with safety regulations.

[0065] Reference Figure 2 and Figure 5 A vertically movable partition 14 is provided between the dispensing area 11 and the temporary storage area 12, which can separate the dispensing area 11 and the temporary storage area 12 into two independent areas.

[0066] The partition 14 can be either electrically driven or pneumatically driven.

[0067] During the liquid retrieval operation, the partition 14 rises vertically, separating the dispensing area 11 and the temporary storage area 12 into two independent zones. At this time, the radioactive drug radiation in the dispensing area 11 is blocked by the partition 14 and cannot diffuse into the temporary storage area 12. After liquid retrieval is completed, as the robotic arm 3 moves the syringe 5 to the temporary storage area 12, the partition 14 descends vertically, connecting the dispensing area 11 and the temporary storage area 12, facilitating the transfer of the syringe 5 by the robotic arm 3. After the transfer is complete, the partition 14 rises again, restoring the isolation between the two zones. The partition 14 can be raised and lowered via electric or pneumatic drive, ensuring smooth and precise lifting movements. By setting up a liftable partition 14, the dispensing area 11 and the temporary storage area 12 can be switched and isolated, which solves the problem of direct connection between the operating area and the outside world and easy radiation diffusion in the prior art. It can effectively block the radioactive radiation in the dispensing area 11 from spreading to the temporary storage area 12, avoid radiation contamination of the syringe 5 in the temporary storage area 12, and also reduce the possibility of radiation spreading to the external environment. In the state of isolation between the two areas, the cleanliness of the dispensing area 11 can be guaranteed, and impurities in the temporary storage area 12 can be prevented from entering the dispensing area 11 and contaminating the medicine, thus improving the standardization and safety of the dispensing operation. The electric or pneumatic drive method can ensure the convenience and stability of the lifting and lowering of the partition 14, adapting to different usage scenarios.

[0068] Reference Figure 1 A transparent observation window 15 is also provided on the side wall of the dispensing area 11.

[0069] Throughout the entire dispensing process, medical personnel can observe the working status of the dispensing area 11 in real time through the transparent observation window 15 on the side wall of the dispensing area 11. This includes the movement of the robotic arm 3, the liquid extraction process of the syringe 5, and the opening and closing of the opening 41 of the original liquid storage module 4. The dispensing progress and operational status can be monitored without opening the dispensing cabinet 1. The technical advantage of this structure is that the transparent observation window 15 ensures the airtightness of the dispensing area 11, preventing radiation leakage caused by opening the dispensing cabinet 1. It also solves the problem in existing technologies where medical personnel cannot observe the dispensing process in real time and cannot easily detect operational abnormalities. Medical personnel can use the observation window to promptly check for problems such as abnormal gripping of the robotic arm 3 and unsmooth liquid extraction, preventing the malfunction from escalating. At the same time, observation can be completed without approaching the dispensing area 11, further reducing the radiation exposure to medical personnel, improving the convenience and safety of operation, and complying with the safety protection specifications for radiopharmaceutical operations.

[0070] Reference Figure 2 The temporary storage area 12 is provided with a rack 16 for placing the syringe 5.

[0071] A switch door is installed on the side wall of the temporary storage area 12. When medical staff need to retrieve the syringe 5, they can open the switch door and retrieve the syringe 5 from the shelf 16.

[0072] Working principle: Each raw material storage module has a raw material bottle 42. The raw material bottle 42 in each raw material storage module stores different radiopharmaceuticals. Before dispensing, the shielding plate 43 in each raw material storage module 4 covers the opening 41. Since the outer shell of the raw material storage module 4 and the shielding plate 43 are both made of lead, the interaction between different radiopharmaceuticals can be avoided, thus ensuring the efficacy of the drug.

[0073] Before dispensing, sterilized syringes 5 are placed sequentially on the rack 16, and the door of the temporary storage area 12 is closed. The temporary storage area 12 is equipped with a sterilization device, which sterilizes the temporary storage area 12 each time the door is opened and closed. The specific structure of the sterilization device is existing technology and will not be described in detail here. Subsequently, the first linear actuator 2 drives the robotic arm 3 to move to the end of the dispensing area 11 near the temporary storage area 12, and the partition 14 is lowered. At this time, the dispensing area 11 and the temporary storage area 12 are connected. The robotic arm 3 has a gripping end, which passes over the partition 14 and enters the temporary storage area 12, gripping and removing a syringe 5 placed on the rack 16. Then, according to the program settings, the robotic arm 3 and the syringe 5 it grips move to the side of the corresponding original liquid storage module 4 driven by the first linear actuator 2. Then the partition 14 rises, separating the dispensing area 11 and the temporary storage area 12. During dispensing, the opening 41 on the corresponding stock solution storage module 4 is open, while the openings 41 on the other stock solution storage modules 4 are closed. That is, the baffle 43 in the corresponding stock solution storage module 4 moves out from directly below the opening 41. It is worth noting that the upper part of the stock solution bottle 42 is provided with a dispensing port for the syringe 5 to draw liquid. To prevent the stock solution bottle 42 from remaining open and causing the radiopharmaceutical to evaporate, before dispensing, the stopper 431 at the lower part of the baffle 43 is inserted into the dispensing port at the upper part of the stock solution bottle 42. Therefore, before the baffle 43 rotates, the first... The second linear actuator 46 drives the lifting frame 45 to descend, causing the original liquid bottle 42 to detach from the cap. Then, the drive unit 44 drives the baffle plate 43 to rotate, causing the baffle plate 43 to move out from the opening 41. At this time, the fan 13 starts, and the filtered air from the outside is introduced into the dispensing area 11. The air enters the original liquid storage module 4 through the open opening 41 and is discharged through the exhaust port 47 on the original liquid storage module 4, so that the airflow at the opening 41 flows from top to bottom, avoiding the volatilization of radioactive drugs during liquid extraction, which would cause radioactive drugs to enter the dispensing area 11. Then, liquid retrieval begins. During retrieval, the gripper end of the robotic arm 3 holds the syringe 5 and lowers it to retrieve the liquid. The lower end of the syringe 5 passes through the opening 41 and the retrieval port from top to bottom. After retrieval is completed, the gripper end of the robotic arm 3 holds the syringe 5 and raises it, causing the lower end of the syringe 5 to remain at the opening 41 for a period of time. This is because the airflow at the opening 41 flows from top to bottom. Through the flow of airflow, the residual liquid adhering to the outside of the syringe 5 can fall back into the original liquid bottle 42. This process only takes one to two seconds, and the air in the dispensing area 11 has been filtered, so the falling liquid will not contaminate the original liquid bottle 42.Subsequently, the robotic arm 3, holding the syringe 5, rises above the original liquid storage module 4. The drive unit 44 drives the baffle 43 to block the opening 41. The first linear actuator 2 drives the robotic arm 3 to move towards the temporary storage area 12. Then, the partition 14 descends, and the gripping end of the robotic arm 3 places the syringe 5, after liquid dispensing, onto the placement rack 16. The robotic arm 3 then grips other syringes 5 placed on the placement rack 16 again, repeating the above operation. It is worth noting that the syringes 5 on the placement rack 16 are covered with a lead layer, which can ensure that the liquids in the dispensing syringes 5 are different and will not cause mutual interference of radioactivity between the liquids. At the same time, it can also reduce the radiation exposure of medical staff when using the syringes 5 to inject patients.

[0074] The above embodiments only illustrate one or more implementations of the present invention, and their descriptions are relatively specific and detailed, but they should not be construed as limiting the scope of protection of the present invention. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these all fall within the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be determined by the appended claims.

Claims

1. An automated dispensing device for radiopharmaceuticals, comprising a dispensing cabinet (1); Its features are, The dispensing cabinet (1) is divided into a dispensing area (11) and a temporary storage area (12) along the horizontal direction. The dispensing device also includes: The first linear actuator (2) is disposed in the dispensing area (11) along the length direction of the dispensing cabinet (1); A robotic arm (3) is mounted on a first linear actuator (2). The first linear actuator (2) is used to drive the robotic arm (3) to move along the length direction of the dispensing cabinet (1). The operating area formed by the robotic arm (3) under the drive of the first linear actuator (2) covers the dispensing area (11) and the temporary storage area (12). The robotic arm (3) is used to hold a syringe (5) to take medicine. The syringe (5) is covered with a lead layer. The original liquid storage module (4) has multiple components arranged in the dispensing area (11) parallel to the length direction of the first linear actuator (2). The upper part of the original liquid storage module (4) is provided with an opening (41) that can be opened or closed. The original liquid bottle (42) for storing radiopharmaceutical original liquid is located directly below the opening (41).

2. The automatic radiopharmaceutical dispensing device according to claim 1, characterized in that, The original liquid storage module (4) is also equipped with: A baffle plate (43) is movably positioned below the opening (41). When the baffle plate (43) moves to the position directly below the opening (41), the opening (41) closes. A drive unit (44) is located on one side of the moving plate and is used to drive the shield (43) to move.

3. The automatic dispensing device for radiopharmaceuticals according to claim 2, characterized in that, The outer casing of both the shield (43) and the original liquid storage module (4) is made of lead.

4. The automatic dispensing device for radiopharmaceuticals according to claim 2, characterized in that, The original liquid storage module (4) is also equipped with: The lifting frame (45) is vertically movable and positioned below the shield (43), and the original liquid bottle (42) is positioned on the upper surface of the lifting frame (45).

5. The automatic dispensing device for radiopharmaceuticals according to claim 4, characterized in that, A stopper (431) is fixedly provided at the lower part of the shield (43), and the stopper (431) can cover the upper part of the original liquid bottle (42).

6. The automatic dispensing device for radiopharmaceuticals according to claim 1, characterized in that, The original liquid storage module (4) is provided with an exhaust port (47) on its side wall, and the dispensing area (11) is provided with a fan (13) that introduces filtered outside air into the dispensing area (11) on its side wall.

7. The automatic dispensing device for radiopharmaceuticals according to claim 6, characterized in that, The outer side of the original liquid storage module (4) is provided with a radioactive material filter (6) that is connected to the exhaust port (47).

8. The automatic dispensing device for radiopharmaceuticals according to claim 1, characterized in that, A vertically movable partition (14) is provided between the dispensing area (11) and the temporary storage area (12), which can separate the dispensing area (11) and the temporary storage area (12) into two independent areas.

9. An automatic radiopharmaceutical dispensing device according to claim 1, characterized in that, A transparent observation window (15) is also provided on the side wall of the dispensing area (11).

10. An automatic radiopharmaceutical dispensing device according to claim 1, characterized in that, The temporary storage area (12) is provided with a rack (16) for placing the syringe (5).

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