A topical filamentous biocare composition, its formulation, and a method for preparing a traditional Chinese medicine active ingredient.

Abstract

This invention belongs to the field of traditional Chinese medicine composition technology, specifically relating to a topical filamentous growth care composition, its formulation, and a method for preparing the active traditional Chinese medicine extract. The topical filamentous growth care composition includes the following raw materials: Cyperus rotundus, Equisetum hyemale, and Sandalwood. These three traditional Chinese medicines work synergistically to effectively soften and disperse nodules, soothe skin lesions, and improve local abnormal keratinization. This invention also provides a method for preparing the active traditional Chinese medicine extract of this composition, employing a segmented extraction process. First, Cyperus rotundus and Equisetum hyemale are boiled in water and simmered at a constant temperature. After cooling, Sandalwood is added and the mixture is sealed and simmered at a constant temperature. Then, the extract is concentrated under low temperature and reduced pressure to obtain the active extract. This method maximizes the retention of the effective components of each raw material and reduces external irritation. The traditional Chinese medicine composition of this invention is scientifically formulated, mild, safe, and suitable for long-term care of thin and delicate epidermis. It can effectively improve the symptoms of filamentous growths, reduce the recurrence rate, meets the requirements of industrial production, and has good prospects for industrial application.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine composition technology, specifically relating to a topical filamentous growth biological care composition, its formulation, and a method for preparing the active traditional Chinese medicine extract. Background Technology

[0002] Filamentous growths are benign skin lesions caused by low-risk human papillomavirus (HPV) infection of human epidermal cells, leading to abnormal differentiation and proliferation of epithelial cells. As a common type of warts, they often occur on exposed areas such as the neck, face, and eyelids. They are contagious and can spread through direct contact, scratching, and autoinoculation. They are prone to recurrence, seriously affecting the appearance of the patient's skin and causing psychological distress and inconvenience in daily life.

[0003] Currently, the treatment of human papillomavirus-related filamentous growths is mainly divided into two categories: physical therapy and topical care. Commonly used physical removal methods include liquid nitrogen cryotherapy, laser therapy, and electrocautery. While these methods can quickly remove the warts, they have significant drawbacks: they cause trauma to surrounding normal skin tissue during treatment, and postoperative scarring and pigmentation are common. They are particularly unsuitable for delicate areas like the face and neck, and cannot fundamentally inhibit viral-induced abnormal proliferation, leading to a high recurrence rate and failing to meet patients' needs for gentle and safe care.

[0004] Traditional Chinese medicine (TCM) possesses unique advantages in the field of topical care for skin growths due to its mild nature and minimal side effects. Attempts to utilize TCM compositions for topical care have emerged in related technologies. However, existing TCM-related technologies often employ two-component formulations, which have the following drawbacks: First, the synergistic effect of two-component formulations is insufficient, resulting in poor transdermal efficacy and difficulty in effectively targeting the affected skin, failing to fully realize the effects of softening and dispersing nodules and soothing skin lesions. Second, existing TCM compositions tend to be highly irritating, and long-term topical use can easily lead to problems such as skin dullness and dryness, making them unsuitable for the long-term care needs of the delicate epidermis of the face, head, and neck.

[0005] Meanwhile, in terms of the preparation process of traditional Chinese medicine compositions, existing technologies mostly adopt single decoction or mixed extraction methods, without taking into account the differences in the component characteristics of different traditional Chinese medicine raw materials.

[0006] In view of this, in response to the problems existing in the external care techniques for filamentous growths, such as large physical therapy trauma, unreasonable compatibility of traditional Chinese medicine compositions, imperfect preparation processes, single dosage forms, and insufficient safety and effectiveness, it is urgent to develop a topical traditional Chinese medicine care composition and its preparation method and formulation that is scientifically compatible, has a reasonable preparation process, is gentle and safe, is suitable for the care of thin and delicate epidermis, and can effectively improve the symptoms of filamentous growths and reduce the probability of recurrence. Summary of the Invention

[0007] Based on the above technical background, the main objective of this invention is to provide a topical filamentous growth care composition, its formulation, and a method for preparing a traditional Chinese medicine active liquid, so as to overcome the shortcomings of existing topical filamentous growth care compositions, such as unreasonable compatibility, insufficient safety and effectiveness, and high recurrence rate.

[0008] To achieve the aforementioned objectives, the technical solution adopted by this invention includes:

[0009] The first aspect of the present invention is to provide a topical filamentous growth care composition, the topical filamentous growth care composition comprising the following raw materials in parts by weight: 25-35 parts by weight of Cyperus rotundus, 25-35 parts by weight of Equisetum hyemale, and 4-8 parts by weight of sandalwood.

[0010] Preferably, the external filamentous growth care composition comprises the following raw materials in parts by weight: 30 parts by weight of Cyperus rotundus, 30 parts by weight of Equisetum hyemale, and 6 parts by weight of sandalwood.

[0011] Preferably, the external filamentous biocare composition comprises the following raw materials in parts by weight: 25 parts by weight of Cyperus rotundus, 25 parts by weight of Equisetum hyemale, and 4 parts by weight of sandalwood.

[0012] Preferably, the external filamentous biocare composition comprises the following raw materials in parts by weight: 35 parts by weight of Cyperus rotundus, 35 parts by weight of Equisetum hyemale, and 8 parts by weight of sandalwood.

[0013] The efficacy and function of each ingredient in the topical filamentous growth care composition are as follows: Cyperus rotundus: It is neutral in nature and pungent in taste. It has the effects of soothing the liver and relieving depression, regulating menstruation and relieving pain, and calming the fetus. It is mainly used to treat diseases such as liver qi stagnation, irregular menstruation, dysmenorrhea, amenorrhea, and fatigue.

[0014] Horsetail: It is mild in nature, sweet and bitter in taste, similar to ephedra. It has the effects of dispersing wind-heat, stopping bleeding, and improving eyesight. It can clear heat and dispel wind, induce sweating and relieve muscle tension, and can be used to treat sore throat, carbuncles, and other diseases. Horsetail can also moisten dryness, reduce heat, cool the blood and stop bleeding, and can be used to treat diarrhea, dysentery, metrorrhagia, leukorrhea, hemorrhoidal bleeding, and other diseases. Horsetail enters the liver and gallbladder meridians, and can dispel wind-heat in the blood of the liver and gallbladder meridians, causing blood to rush to the eyes, thus clearing away eye obstructions and improving vision. Horsetail also has anti-inflammatory effects, and has a good inhibitory effect on Staphylococcus aureus, Escherichia coli, Bacillus anthracis, Shigella, etc.

[0015] Sandalwood: pungent in taste and warm in nature, it enters the lung, stomach, and spleen meridians. It has the functions of warming the middle jiao (spleen and stomach), dispelling cold, regulating qi, harmonizing the stomach, and relieving pain. It is particularly effective in treating chest tightness and pain caused by cold pathogens. Sandalwood is also suitable for upper abdominal stomach pain caused by cold pathogens and can be used to treat stomach pain, belching, and hiccups.

[0016] The second aspect of this invention provides a method for preparing a topical herbal active ingredient solution for treating filamentous growths, wherein the herbal active ingredient solution is prepared from the herbal composition described in the first aspect of this invention, and the preparation method includes the following steps: Step 1: Add water to raw Cyperus rotundus and Equisetum hyemale, heat to a boil, and then simmer at a constant temperature. Step 2: Add sandalwood to the cooled decoction from Step 1, seal and simmer at a constant temperature, then separate the solid and liquid. Step 3: The filtrate obtained after solid-liquid separation is concentrated under low temperature and reduced pressure to obtain the active original solution of traditional Chinese medicine for external use in the care of filamentous growths.

[0017] The steps described above are described in detail below.

[0018] In step 1, the amount of water added is 8 to 12 times the total mass of raw Cyperus rotundus and Equisetum hyemale.

[0019] Preferably, the amount of water added is 10 times the total mass of raw Cyperus rotundus and Equisetum hyemale.

[0020] Add water to raw Cyperus rotundus and Equisetum hyemale, heat to a boil, and then simmer at a constant temperature for 20-30 minutes.

[0021] Preferably, water is added to raw Cyperus rotundus and Equisetum hyemale, heated to a boil, and then simmered at a constant temperature for 25 minutes.

[0022] In step 2, after the decoction from step 1 has cooled to 55-65°C, sandalwood is added to the decoction, and the mixture is then sealed and steeped at this temperature for 5-15 minutes.

[0023] Preferably, after the decoction from step 1 has cooled to 60°C, sandalwood is added to the decoction, and the mixture is then sealed and steeped at this temperature for 10 minutes.

[0024] The volatile oils in sandalwood are heat-sensitive and easily decompose and denature at high temperatures. Traditional high-temperature mixed extraction processes result in a significant loss of these volatile oils, which greatly reduces the activity and skin penetration of the composition, failing to fully realize its soothing and repairing effects. Furthermore, raw Cyperus rotundus and Equisetum hyemale require proper decoction to fully release their active ingredients. Therefore, this method first performs high-temperature water extraction on raw Cyperus rotundus and Equisetum hyemale, followed by constant-temperature soaking with sandalwood at a low temperature. This improves the extraction efficiency of the active ingredients in raw Cyperus rotundus, Equisetum hyemale, and sandalwood, and enhances the activity stability and repeatability of the prepared herbal formulation.

[0025] In step 3, the filtrate obtained after solid-liquid separation is concentrated under low temperature and reduced pressure. The concentration temperature is controlled at 45℃~55℃ and the vacuum degree is maintained at -0.06~-0.08 MPa. The concentration is carried out until the relative density of the original liquid is 1.05~1.10 (25℃). This is to preserve the active ingredients of each Chinese herbal raw material to the greatest extent and ensure the nursing efficacy of the composition.

[0026] Preferably, the filtrate obtained after solid-liquid separation is concentrated under low temperature and reduced pressure. The concentration temperature is controlled at 50°C and the vacuum degree is maintained at -0.07 MPa until the relative density of the original liquid is 1.07 to 1.10 (25°C).

[0027] A third aspect of the present invention is to provide a topical filamentous growth care preparation, wherein the topical filamentous growth care preparation is prepared from the topical filamentous growth care traditional Chinese medicine active stock solution obtained by the preparation method described in the second aspect of the present invention.

[0028] The nursing preparations include a wet compress solution for filamentous growth care, a skin repair gel, and a moisturizing and soothing cream.

[0029] The beneficial effects of this invention are as follows: (1) The composition of the present invention uses Cyperus rotundus, Equisetum hyemale and sandalwood in a specific weight ratio to overcome the limitations of the existing two-component composition. The three components work synergistically and are reasonably matched. They can effectively soften and disperse nodules, soothe skin lesions, improve local abnormal keratinization, and act specifically on human papillomavirus-related filamentous lesions. The composition is safer, has better nursing effect, and has a lower recurrence rate.

[0030] (2) The preparation method of the present invention first decocts raw Cyperus rotundus and Equisetum hyemale at high temperature, and then adds sandalwood to the decoction after cooling for soaking in a segmented extraction process. Combined with low temperature and low pressure concentration conditions, it can ensure the full release of the effective components in raw Cyperus rotundus and Equisetum hyemale, and retain the heat-sensitive volatile oil components in sandalwood to the greatest extent, thereby improving the retention rate of effective active components in the prepared Chinese medicine active original liquid, enhancing the skin penetration and utilization rate of active components, and reducing external irritation. This solves the problems of large loss of active components and insufficient efficacy in the existing process preparation method.

[0031] (3) The active liquid of traditional Chinese medicine prepared by the traditional Chinese medicine composition of the present invention does not contain strong acid corrosive substances or hormones. It can be gently applied to the skin lesion site without damaging normal skin tissue or the dermis. It will not leave scars or cause long-term pigmentation abnormalities. It has low irritation to the epidermis and can be used for long-term external care of thin and delicate epidermis such as the head, face and neck. It is suitable for a wide range of people and its safety is controllable.

[0032] (4) The Chinese medicine composition and the prepared Chinese medicine active liquid described in this invention can effectively inhibit the abnormal proliferation of skin growths, reduce the self-spread of filamentous growths, and significantly reduce the probability of recurrence. Compared with existing physical therapy and traditional Chinese medicine nursing methods, it can better meet the needs of patients for long-term care and reduce recurrence.

[0033] (5) The preparation method of the present invention has clear steps and is simple. The prepared active stock solution of traditional Chinese medicine has strong activity stability and good repeatability, which meets the requirements of industrial mass production and has good prospects for industrial application.

[0034] (6) Based on standardized active ingredients of traditional Chinese medicine, this invention can prepare three types of external preparations: wet compress solution, skin repair gel, and soothing and nourishing cream. This forms an integrated multi-dosage form matching technology, which can meet the nursing needs of patients with different scenarios and skin types, and solves the shortcomings of existing technologies with single dosage forms. It is gentle and safe and suitable for long-term care of thin and delicate epidermis, and can effectively improve the symptoms of filamentous growths and reduce the probability of recurrence. Detailed Implementation

[0035] The present invention will now be described in detail, and its features and advantages will become clearer and more apparent from these descriptions.

[0036] Example The present invention is further illustrated below with specific examples. These embodiments are merely illustrative and not intended to limit the scope of the invention. All raw materials used in the embodiments of the present invention are commercially available.

[0037] Example 1 A topical filamentous growth care composition comprising the following raw materials in parts by weight: 30 parts by weight of Cyperus rotundus, 30 parts by weight of Equisetum hyemale, and 6 parts by weight of sandalwood.

[0038] Example 2 A topical filamentous growth care composition comprising the following raw materials in parts by weight: 25 parts by weight of Cyperus rotundus, 25 parts by weight of Equisetum hyemale, and 4 parts by weight of sandalwood.

[0039] Example 3 A topical filamentous growth care composition comprising the following raw materials in parts by weight: 35 parts by weight of Cyperus rotundus, 35 parts by weight of Equisetum hyemale, and 8 parts by weight of sandalwood.

[0040] Example 4 A method for preparing a topical herbal active ingredient solution for treating filamentous growths, the method comprising the following steps: Weigh each raw material according to the weight proportions described in Example 1, and set aside for later use.

[0041] Step 1: Add water to the weighed raw Cyperus rotundus and Equisetum hyemale. The amount of water added should be 10 times the total mass of the raw Cyperus rotundus and Equisetum hyemale. Heat to a boil and then simmer at a constant temperature for 25 minutes to obtain the Chinese herbal medicine liquid. Step 2: After the decoction from Step 1 has cooled to 60°C, add the weighed sandalwood to the decoction and keep it sealed and soaked at this temperature for 10 minutes. Then, separate the solid and liquid.

[0042] Step 3: The filtrate obtained after solid-liquid separation in Step 2 is concentrated under low temperature and reduced pressure. The concentration temperature is controlled at 50℃ and the vacuum degree is maintained at -0.07 MPa. The concentration is carried out until the relative density of the original liquid is 1.07~1.10 (25℃) to obtain the active original liquid of traditional Chinese medicine.

[0043] Example 5 The preparation of the topical filamentous growth care herbal active stock solution was carried out in a manner similar to that of Example 4, except that the raw materials were weighed according to the weight proportions described in Example 2, and the remaining steps were the same as those in Example 4.

[0044] Example 6 The preparation of the topical filamentous growth care herbal active stock solution was carried out in a manner similar to that of Example 4, except that the raw materials were weighed according to the weight proportions described in Example 3, and the remaining steps were the same as those in Example 4.

[0045] Comparative Example Comparative Example 1 A topical filamentous growth care composition comprising the following raw materials in parts by weight: 30 parts by weight of Cyperus rotundus and 30 parts by weight of Equisetum hyemale.

[0046] A method for preparing a topical herbal active ingredient solution for treating filamentous growths, the method comprising the following steps: Weigh each ingredient according to the above-mentioned weight proportions and set aside.

[0047] Step 1: Add water to the weighed raw Cyperus rotundus and Equisetum hyemale. The amount of water added should be 10 times the total mass of the raw Cyperus rotundus and Equisetum hyemale. Heat to a boil and then simmer at a constant temperature for 25 minutes to obtain the Chinese herbal medicine liquid. Step 2: Separate the solid and liquid components of the Chinese herbal medicine liquid obtained in Step 1. Concentrate the obtained filtrate under low temperature and reduced pressure. The concentration temperature is controlled at 50℃ and the vacuum degree is maintained at -0.07 MPa. Concentrate until the relative density of the original liquid is 1.07~1.10 (25℃) to obtain the active original liquid of Chinese herbal medicine.

[0048] Comparative Example 2 A topical filamentous growth care composition comprising the following raw materials in parts by weight: 30 parts by weight of horsetail and 6 parts by weight of sandalwood.

[0049] A method for preparing a topical herbal active ingredient solution for treating filamentous growths, the method comprising the following steps: Weigh each raw material according to the weight proportions described in Example 1, and set aside for later use.

[0050] Step 1: Add water to the weighed horsetail, the amount of water being 10 times the total mass of the horsetail. Heat to a boil and then simmer at a constant temperature for 25 minutes to obtain the Chinese herbal medicine liquid. Step 2: After the decoction from Step 1 has cooled to 60°C, add the weighed sandalwood to the decoction and keep it sealed and soaked at this temperature for 10 minutes. Then, separate the solid and liquid.

[0051] Step 3: The filtrate obtained after solid-liquid separation in Step 2 is concentrated under low temperature and reduced pressure. The concentration temperature is controlled at 50℃ and the vacuum degree is maintained at -0.07 MPa. The concentration is carried out until the relative density of the original liquid is 1.07~1.10 (25℃) to obtain the active original liquid of traditional Chinese medicine.

[0052] Comparative Example 3 A topical filamentous biocare composition comprising the following raw materials in parts by weight: 30 parts by weight of Cyperus rotundus and 6 parts by weight of sandalwood.

[0053] A method for preparing a topical herbal active ingredient solution for treating filamentous growths, the method comprising the following steps: Weigh each raw material according to the weight proportions described in Example 1, and set aside for later use.

[0054] Step 1: Add water to the weighed raw Cyperus rotundus. The amount of water added should be 10 times the total mass of the raw Cyperus rotundus. Heat to a boil and then simmer at a constant temperature for 25 minutes to obtain the Chinese herbal medicine liquid. Step 2: After the decoction from Step 1 has cooled to 60°C, add the weighed sandalwood to the decoction and keep it sealed and soaked at this temperature for 10 minutes. Then, separate the solid and liquid.

[0055] Step 3: The filtrate obtained after solid-liquid separation in Step 2 is concentrated under low temperature and reduced pressure. The concentration temperature is controlled at 50℃ and the vacuum degree is maintained at -0.07 MPa. The concentration is carried out until the relative density of the original liquid is 1.07~1.10 (25℃) to obtain the active original liquid of traditional Chinese medicine.

[0056] Experimental Example Experiment Example 1 Effect Test The efficacy of the active traditional Chinese medicine extracts prepared in Examples 4-6 and Comparative Examples 1-3 was tested respectively. The specific testing process is as follows: (1) Test subjects: 210 patients who met the diagnostic criteria for filamentous growths were selected. Their ages ranged from 18 to 65 years, and the duration of their disease ranged from 3 months to 2 years. The lesions were mainly located on the neck, face, and eyelids, areas with thin and delicate epidermis. Patients with severe skin diseases, allergies, liver or kidney dysfunction, or who were pregnant or lactating were excluded. The patients were randomly divided into 7 groups of 30 patients each, corresponding to Examples 4-6 and Comparative Examples 1-3, respectively. There were no statistically significant differences in age, duration of disease, number of lesions, and location among the groups (P>0.05), making them comparable.

[0057] (2) Test samples: The active traditional Chinese medicine stock solution prepared in Examples 4 to 6 (corresponding to the compositions in Examples 1 to 3 respectively) and the active traditional Chinese medicine stock solution prepared in Comparative Examples 1 to 3. All samples were of the same specifications, sealed and stored at room temperature.

[0058] (3) Test method: Patients in each group applied the corresponding sample twice a day (once in the morning and once in the evening). Before application, clean the affected area with warm water and dry it. Take an appropriate amount of the original solution and apply it evenly to the affected area and the surrounding 0.5cm area of ​​skin. Gently massage until fully absorbed. Continuous use for 4 weeks constitutes one course of treatment. No other products, drugs or physical therapy methods related to the care of filamentous growths are used throughout the course.

[0059] (4) Observation indicators and records: Observe the changes in the patient's skin lesions and skin irritation reactions (such as redness, swelling, itching, desquamation, etc.) daily, and record the number and size of skin lesions once a week; after the course of treatment, count the number of cases with significant effect, effective and ineffective in each group, and calculate the total effective rate; after the course of treatment, follow up for 3 months, count the number of relapses in each group, and calculate the relapse rate.

[0060] (5) Judgment criteria: The following criteria shall be strictly followed to determine whether a product is effective, valid, or invalid.

[0061] Significant effect: After the course of treatment, the skin lesions completely disappeared (all warts fell off), the skin at the lesion site returned to normal, without redness, swelling, pigmentation, or obvious skin irritation; no recurrence was observed during the 3-month follow-up.

[0062] Effective: After the course of treatment, the skin lesions partially subside (≥50% of the warts fall off), the size of the skin lesions is significantly reduced (≥50%), there is no obvious redness, swelling or itching of the skin at the lesion site, and mild pigmentation can fade on its own; the recurrence rate is ≤10% during a 3-month follow-up.

[0063] Ineffective: If there is no significant change in the skin lesions after the course of treatment (wart shedding <50%) or the condition worsens, the skin lesion volume shrinks <50%, or there is a significant skin irritation reaction (such as severe redness, swelling, itching, desquamation, etc.), the use of the sample should be discontinued; the recurrence rate during the 3-month follow-up is >10%.

[0064] Note: Overall effective rate = (number of cases with significant effect + number of cases with effect) / total number of cases × 100%; relapse rate = number of relapsed cases / total number of effective cases × 100% (ineffective cases are not included in the relapse rate statistics). The test results are shown in Table 1.

[0065] Table 1

[0066] As shown in Table 1, the total effective rate of the active traditional Chinese medicine extracts prepared in Examples 4 and 5 was higher than 93%, and the recurrence rate was lower than 3.8%. In contrast, the total effective rate of the active traditional Chinese medicine extracts prepared in Comparative Examples 1 and 3 was lower than 60%, and the recurrence rate was higher than 25%. These results indicate that Cyperus rotundus, Equisetum hyemale, and Santalum album are all indispensable. Only by simultaneously using Cyperus rotundus, Equisetum hyemale, and Santalum album, and by combining and extracting them according to the dosages specified in this invention, can the therapeutic effect on filamentous growths be most effectively improved, and the recurrence rate of filamentous growths be inhibited.

[0067] The present invention has been described in detail above with reference to specific embodiments and exemplary examples; however, these descriptions should not be construed as limiting the present invention. Those skilled in the art will understand that various equivalent substitutions, modifications, or improvements can be made to the technical solutions and embodiments of the present invention without departing from the spirit and scope of the invention, and all such modifications and improvements fall within the scope of the present invention. The scope of protection of the present invention is defined by the appended claims.

Claims

1. An external filamentous excrescence care composition characterized in that, The topical filamentous growth care composition comprises the following raw materials in parts by weight: 25-35 parts by weight of Cyperus rotundus, 25-35 parts by weight of Equisetum hyemale, and 4-8 parts by weight of sandalwood.

2. The topical filamentous biocare composition according to claim 1, characterized in that, The topical filamentous growth care composition comprises the following raw materials in parts by weight: 30 parts by weight of Cyperus rotundus, 30 parts by weight of Equisetum hyemale, and 6 parts by weight of sandalwood.

3. The topical filamentous biocare composition according to claim 1, characterized in that, The topical filamentous growth care composition comprises the following raw materials in parts by weight: 25 parts by weight of Cyperus rotundus, 25 parts by weight of Equisetum hyemale, and 4 parts by weight of sandalwood.

4. The topical filamentous growth care kit according to claim 1, characterized in that, The topical filamentous growth care composition comprises the following raw materials in parts by weight: 35 parts by weight of Cyperus rotundus, 35 parts by weight of Equisetum hyemale, and 8 parts by weight of sandalwood.

5. A method for preparing a topical herbal active ingredient solution for treating filamentous growths, wherein the herbal active ingredient solution is prepared from the herbal composition according to any one of claims 1 to 4, and the preparation method includes the following steps: Step 1: Add water to raw Cyperus rotundus and Equisetum hyemale, heat to a boil, and then simmer at a constant temperature. Step 2: Add sandalwood to the cooled decoction from Step 1, seal and simmer at a constant temperature, then separate the solid and liquid. Step 3: The filtrate obtained after solid-liquid separation is concentrated under low temperature and reduced pressure to obtain the active original solution of traditional Chinese medicine for external use in the care of filamentous growths.

6. The production method according to claim 5, wherein In step 1, The amount of water added is 8 to 12 times the total mass of raw Cyperus rotundus and Equisetum hyemale; Add water to raw Cyperus rotundus and Equisetum hyemale, heat to a boil, and then simmer at a constant temperature for 20-30 minutes.

7. The preparation method according to claim 5, characterized in that, In step 2, After the decoction from step 1 has cooled to 55-65°C, add sandalwood to the decoction and keep it sealed and steeped at this temperature for 5-15 minutes.

8. The preparation method according to claim 5, characterized in that, In step 3, The filtrate obtained after solid-liquid separation is concentrated under low temperature and reduced pressure. The concentration temperature is controlled at 45℃~55℃ and the vacuum degree is maintained at -0.06~-0.08 MPa until the relative density of the original liquid is 1.05~1.10 (25℃).

9. A topical filamentous biocare preparation, characterized in that, The nursing preparation is prepared from the topical filamentous growth care traditional Chinese medicine active stock solution obtained by the preparation method described in any one of claims 5 to 8.

10. The topical filamentous biocare preparation according to claim 9, characterized in that, The topical filamentous growth care preparations include filamentous growth care wet compress liquid, skin repair gel, and moisturizing and soothing cream.

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