Improvements in or relating to organic compounds

Abstract

This invention relates to improvements in or related to organic compounds. Specifically, it relates to fragrance compositions suitable for improving sleep quality and consumer products comprising said fragrance compositions. The fragrance composition contains at least two fragrance ingredients having a known Sandman classification (SC) value of at least 1.35. Preferred fragrance compositions exhibit SC values ​​of 1.35 to about 150, more specifically 1.35 to about 75, and still more specifically 1.35 to about 3. This composition improves sleep quality.

Description

[0001] This application is a divisional application of Chinese patent application No. 201680015897.2, filed on March 16, 2016, entitled "Improvements in or related to organic compounds".

[0002] This invention relates to fragrance compositions suitable for improving sleep quality and consumer products containing said fragrance compositions.

[0003] It has been observed that fragrance components and essential oils can influence mood states, and in particular, they have been suggested to produce feelings of relaxation and well-being. However, perceptions of scent are subjective, and while individuals within a cultural group may share common associations with specific scents, these associations are not always recognized across cultures and regions. For example, lavender may have a profound relaxing effect on consumers in Western Europe, but people in other geographical areas may not share this association.

[0004] While the transient psychological effects of fragrances on human behavior and mood have been studied, few experimental studies have observed the effects of fragrances on sleep quality. Some research suggests that scents can have a positive impact on sleep quality. However, these studies primarily rely on the effects of single ingredients or on highly basic combinations of ingredients that lack the expected pleasurable properties and complexity of fragrances suitable for inclusion in consumer products. Some work has been conducted using electroencephalography (EEG) to investigate the effects of scents on sleep patterns. As is well known in the art, EEG is a method for measuring real-time brain activity from the scalp surface with high transient resolution and therefore remains the most commonly used technique for describing the differences between wakefulness and sleep.

[0005] The existing technology suggests that certain odors may affect the mood and emotions of human subjects and also affect sleep patterns. EEG is known to be a technique that can measure brain activity as a response to odor exposure. To the best of the applicant's knowledge, the existing technology does not teach a reliable and objective method for selecting a combination of fragrance ingredients that is both effective and complex and that is associated with improved sleep quality.

[0006] The applicant has addressed this deficiency in the prior art and provided a method that allows fragrance manufacturers to create a harmony of functional fragrances that both promote sleep quality and possess pleasurable properties and complexity.

[0007] Therefore, in a first aspect, the present invention provides a flavoring composition comprising at least two, more specifically at least five, more specifically ten or more flavoring ingredients having a known Sandman Classifier (SC) value of at least 1.35. Preferred flavoring compositions exhibit SC values ​​of 1.35 to about 150, more specifically 1.35 to about 75, and still more specifically 1.35 to about 3.

[0008] The Sandman classification (SC) value of the flavoring composition is derived from the brainwave activity of human subjects measured after inhalation of the flavoring composition. Brainwave activity was measured via EEG using a standard 10-20 electrode system. The SC value is provided by the following formula:

[0009] SC = ((а1 ce + Θ ce ) / δ tem ) + (Θ / а2)

[0010] in:

[0011] a1 ce This indicates an oscillation frequency of 8-12 Hz at the center electrodes C3, C4, and Cz. -1 Amplitude value of brainwave activity

[0012] Θ ce This represents the amplitude of theta brainwave activity with an oscillation frequency of 4-7 Hz at the central electrodes C3, C4, and Cz.

[0013] δ tem The amplitude values ​​of theta brainwave activity with oscillation frequencies of 0.1-3 Hz on the temporal electrodes T7 and T8; and

[0014] Θ / а2 represents the amplitude of theta brainwave activity with an oscillation frequency of 4-7 Hz and an oscillation frequency of 12-15 Hz through all electrodes. -2 is the ratio of brainwave amplitude values.

[0015] In one specific embodiment of the present invention, the fragrance composition comprises a fragrance ingredient selected from:

[0016] A) At least one citrus component, particularly selected from the group consisting of about 1 wt% to about 30 wt%, more specifically about 1.2 wt% to 28.9 wt%, of the total amount of flavoring ingredients used in the flavoring composition:

[0017] Bergamot oil, essential oil, extract, fragrance base, substitutes or alternatives, such as Italian pressed bergamot oil; Bergamot REC ABX5638; Bergamot fragrance base 104 / 4; Citrile; Citral TECH; Citral diethyl acetal R; Citronellol; Cypermethrin; Dihydromyrcenol; Dimethyloctenone; 2,6-Dimethylheptanol; Fropi; Grapefruit oil, essential oil, extract, substitutes or alternatives, such as ultra-concentrated grapefruit juice 7108A or grapefruit oil COSMOS; Lemon oil, essential oil, extract, fragrance base, substitutes or alternatives, such as distilled pure California lemon oil; Italian lemon oil ORPUR COSMOS; Reconstituted lemon oil 1385; Spanish lemon DQ (AC) XN 41482TT; Citrin; Linalool Oxide; Synthetic Linaloyl Acetate; Litsea cubeba oil, essential oil, extract, substitute or alternative, such as Chinese Litsea cubeba oil; Orange oil, essential oil, extract, fragrance base, substitute or alternative, such as MANDARIN ARTESSENCE OIL; Brazilian Fresh Orange Oil ORPUR; Italian Colorless Orange Oil MDORPUR; Washed Orange Oil COSMOS; Mandarin Orange 32048 SAE; Mandarin Orange 32048 SAE / 2; Mandarin Orange MATCH CF; Chrysodium Methane; Myrcene 90; Orange Oil, essential oil, extract, fragrance base, substitute or alternative, such as Orange 49; Orange Aldehyde; California Orange DQ (AC) XN 41228TT; Brazilian Orange Oil; Colorless Orange Oil NS; Florida Orange Oil; SAVON Concentrated Orange Oil (ORANGE SAVON CONC) OIL); Orange (ORANGETERPENELESS) DQ (AC) 41483TT; Distilled Orange Terpenes; Orange Leaf Oil, Essential Oil, Extract, Flavor Base, Substitute or Substitute, e.g., Orange Leaf Oil ORPUR; Cyclocarya Aldehyde B; Isoprene Acetate; Cyclocarya Ether; Tamarind Oil, Essential Oil, Extract, Flavor Base, Substitute or Substitute, e.g., Tamarind AB8212; Mandarin Oil, Essential Oil, Extract, Flavor Base, Substitute or Substitute, e.g., South African Mandarin DQ AC XN41957TT; Terpinene; Isorpinene; and Terpinene Acetate;

[0018] And at least one of at least five ingredients from groups B1-B20, in the amounts shown:

[0019] B1) At least one aldehyde fragrance component comprising about 0.01 wt% to about 1.5 wt%, more specifically about 0.01 wt% to about 1.41 wt% of the fragrance components used in the fragrance composition, selected from: decanal; undecenal; undecenal; lauraldehyde; methyl nonanal; octanal; isononanal; nonanal; nonenal 1% / TEC; C12 aldehyde (dodecanal); isoundecenal; saffron aldehydes, such as saffron 10% / TEC; trans-4-decenal, such as decenal-4-trans, decenal-4-trans 10% / TEC; dihydrofaryl; dodecanal, such as dodecanal 10% / TEC; MYRALDENE; and saffron ester;

[0020] B2) At least one amber component comprising about 0.01 wt% to about 25 wt%, more specifically about 0.01 wt% to about 22.49 wt% of the fragrance components used in the fragrance composition, selected from: ambergris acetal, such as ambergris acetal 1% / TEC; ambergris acetal IPM; Ambermax, such as AMBERMAX 10% / TEC, AMBERMAX 50% / DOWANOL TPM; imperial ambergris, such as imperial ambergris 10% / DPG; ambergris furan; ambergris furan tablets; Belambre, such as BELAMBRE 50% / IPM; ethoxymethoxycyclododecane; cedrol acetate liquid; cedrol methyl ether; super ambergris ether; ambergris ketone; carrageenan; KEPHALIS; TIMBEROL; TRIMFIX O;

[0021] B3) At least one animalic / leather fragrance component, comprising about 0.01 wt% to about 1.5 wt%, more specifically about 0.01 wt% to about 1.41 wt%, of the fragrance components used in the fragrance composition, selected from: ANIMALIS 1745 SUBST. PMF2; juniper oil, essential oil, extract, substitute, or alternative, such as Spanish juniper oil; guaiacol; indole; indole, such as indole, indole 1% / TEC; indoleene liquid, such as indoleene liquid 50% / caster oil; suederal components, such as SUEDERAL LT 0710;

[0022] B4) At least one anise component, selected from: anethole; star anise oil; anisaldehyde; anisyl acetate; dihydroanenethole; tarragon; sweet cumin oil, essential oil, extract, flavor base, substitute or alternative, such as sweet cumin 50% DQ (AC) 24190TT; sweet cumin DQ (AC) N 41632TT; sweet cumin oil; sweet cumin oil TECH;

[0023] B5) At least one balsamic fragrance component comprising about 0.01 wt% to about 0.2 wt%, more specifically about 0.01 wt% to about 0.13 wt% of the fragrance components used in the fragrance composition, selected from: benzoin oil, essential oil, extract, substitute or alternative, such as benzoin SI GU ETA 50% BB AAF0515 41235EH; benzyl alcohol; benzyl cinnamate; frankincense oil, essential oil, extract, substitute or alternative, such as OLIBANUM COEUR DEP FREE 50% / TEC; Somali frankincense oil ORPUR; phenylethylphenyl acetate;

[0024] B6) At least one camphor-like / aromatic ingredient comprising about 0.01 wt% to about 10 wt%, more specifically about 0.01 wt% to about 8.13 wt% of the fragrance ingredients used in the fragrance composition, selected from: artemisia oil, essential oil, extract, substitute or alternative, such as Moroccan artemisia oil ORPUR COSMOS; camphor and camphor oil, essential oil, extract, substitute or alternative, such as camphor; white camphor oil; eucalyptol and eucalyptol oil, essential oil, extract, substitute or alternative, such as eucalyptol; Chinese eucalyptol oil COSMOS; hybrid lavender oil, essential oil, extract, substitute or alternative, such as LAVANDIN BRIALIS DQ(AC) XN 41665TT; French hybrid lavender oil ORPUR; hybrid lavender RGV 4; lavender oil, extract, essential oil, substitute or alternative, such as lavender DQ (AC) XN 41569TT; Rosemary oil, essential oil, extract, substitute or alternative, such as rosemary oil; reconstituted rosemary oil; Thuja oil, essential oil, extract, substitute or alternative, such as Korean Thuja oil;

[0025] B7) At least one floral fragrance component comprising about 30 wt% to about 80 wt%, more specifically about 32 wt% to about 79 wt% of the fragrance components used in the fragrance composition, selected from: acetal CD; pentyl cinnamaldehyde; amyl salicylate; pure nerolidin benzyl acetate; benzyl salicylate; borschtal; citronellol; citronellol acetate; p-cresol methyl ether; extra virgin aldehyde; cyclohexanal; cyclohexyl salicylate; methyl o-aminobenzoate; dimethylphenyl thyl carbinol; dobicarbamate; ethyl linalool; lily of the valley pyran; lily of the valley pyran HC; geraniol; geranium oil, essential oil, extract, substitute or substitute, such as geranium oil 230 / 3 MOD; geranium oil ABQ5629; bourbon geranium oil DQ (AC)XN 41563TT; Gynostemma pentaethyl acetate; Gynostemma pentaethyl butyrate; Methyl dihydrojasmonate; Methyl dihydrojasmonate HC; Salicylate foliol; Hexyl cinnamaldehyde; Hexyl cinnamaldehyde DQ AC XI 41505TT; Hexyl salicylate; Hydroxycitronellal; Isobutylphenyl acetate; Isobutyl salicylate; Hexylcyclopentanone; Jasmine oil, essential oil, extract, substitutes or alternatives, such as Jasmine absolute DQ (AC) 41568TT; JASMIN ARGENT 2; Cis-jasmone; Jasmine ester; Jasmine furan; Lily aldehyde and lily aldehyde substitutes; Linalool; Rose alcohol; Methyl anthranilate; Extra methyl anthranilate; Methyl benzoate; Methyl phenyl acetate; Neroli oil, essential oil, extract, substitutes or alternatives, such as Neroli essential oil base AB 7632; Neroli essential oil (NEROLI) PHASE ESS); NEROLINE crystals; NEROLIONE; orange oil, essential oil, extract, substitute or alternative, e.g., neroli TEC AB 2169E; sweet orange crystals; ORANGER FLEUR CREME 1103 / 20; tetrahydrogeraniol; paeonol; PETALIA; phenyl ethyl acetate; phenethyl alcohol; phenyl ethyl isovalerate; phenyl ethyl salicylate crystals; crystallized rose; 9-decenol; rose oil, essential oil, extract, substitute or alternative, e.g., rose base ABF0339A - K182572; rose TW 62 / 10 / 20; super mugwort; pure terpineol; tetrahydrolinalool; linden ester; ethylnaphthyl methyl ether; ylang-ylang oil, essential oil, extract, substitute or alternative, e.g., ylang-ylang AB 0388A; ylang-ylang ECO essential oil;

[0026] B8) At least one fruity aroma component comprising about 0.01 wt% to about 22 wt%, more specifically about 0.01 wt% to about 21.08 wt% of the aroma components used in the aroma composition, selected from: hexyl acetate; o-tert-butylcyclohexyl acetate; gluconate; allyl hexanoate; pineapple ester; allyl heptaate; amyl butyrate; avermanyl ester; apple oil, essential oil, extract, substitute or alternative, such as apple base ABF1016 - K108004; banana oil, essential oil, extract, substitute or alternative, such as banana base ABF0961A - K108784; benzyl butyrate; benzyl isobutyrate; benzyl propionate; butyl acetate; butyric acid; blackcurrant (Cassis) oil, essential oil, extract, substitute or alternative, such as blackcurrant base 345-F CS / 4 / 20; blackcurrant base 345B RECO TEC AB 8408D; Extra Grade Connaught White Oil DQ (AC) 41547TT; Cyclocarpine; Damascene; A-D ... 2927R; Diethyl malonate; Dimethyl benzyl acetate; Dimethyl benzyl butyrate; Dodecyl butyrate; Dodecyl butyrate; Ethyl acetoacetate; Ethyl butyrate; Ethyl hexanoate; Ethyl octanoate; Ethyl isopentyl ketone; Ethyl isobutyrate; Ethyl methyl-2-butyrate; Ethyl heptanoate; Ethyl nonanoate; Ethyl propionate; Ethyl crocinate; Tricyclodecenyl propionate; Strawberry ester; Apple ester; Fructose ester; Tricyclodecenyl isobutyrate; Chivadon; Guard oil, essential oil, extract, substitute or alternative, such as GUAVE DUPLICATION / 2; cis-3-hexenyl butyrate; cis-3-hexenyl isobutyrate; hexyl butyrate; hexyl isobutyrate; premium grade isoamyl acetate; isoamyl butyrate FR; tricyclodecenyl acetate; chamomile ester; melon oil, essential oil, extract, substitute or alternative, such as cantaloupe / 2; methoxyphenyl methyl ethyl ketone; pure methyl heptanone; methyl hexyl ketone; methyl-2-pentenoic acid; 2-fenazate; octyl lactone; peach aldehyde; phenoxyethyl isobutyrate; phenethyl isobutyrate; coconut aldehyde; raspberry aldehyde (N112); strawberry aldehyde;

[0027] B9) At least one fungal ingredient, selected from: pentylvinyl alcohol; ocimene, comprising about 0.001 wt% to about 0.01 wt%, more specifically about 0.001 wt% to about 0.002 wt% of the fragrance ingredients used in the fragrance composition;

[0028] B10) At least one gourmand ingredient, comprising about 0.01 wt% to about 1 wt%, more specifically about 0.01 wt% to about 0.86 wt%, of the flavoring ingredients used in the flavoring composition, selected from: acetyl methyl alcohol; acetyl pyrazine, such as acetyl pyrazine 1% / TEC; benzaldehyde; butyl butyryl lactate; chocolate oil, essential oil, extract, substitute or alternative, such as CHOCOLAT NOIR 1130 TEC / 3; CORYLONE DRIED; CYCLOTENE; ethyl maltol, such as ethyl maltol; ethyl maltol 1% / BA; high furanone, such as high furanone 20% / TEC; hydroxyethylmethylthiazole, such as hydroxyethylmethylthiazole 10% / TEC; vanillyl isobutyrate; maltol isobutyrate;

[0029] B11) At least one green fragrance component, comprising about 0.01 wt% to about 5 wt%, more specifically 0.041 wt% to about 4.28 wt% of the fragrance components used in the fragrance composition, selected from: acetal E; hexanol; food-grade hexanal; sec-butylquinoline; privet aldehyde; diphenyl ether; elintaal; ethyl decantereate (ETHYL) DECADIENOATE); Ethyl dimethyl pyrazine, e.g., pyrazine 1% / TEC; Grupone, e.g., Grupone 10%; Pure Grupone; Styrax acetate; trans-2-hexenal, e.g., trans-2-hexenal 10% / TEC; trans-2-hexenool; cis-3-hexenool; cis-3-hexeno acetate; cis-3-hexeno benzoate; cis-3-hexeno propionate; Isocyclocitral; Isohexylmethoxypyrazine, e.g., isohexylmethoxypyrazine 1% / TEC; Chlorpheniramine; Privet acetal; Marseillealdehyde; Octyryne carboxylate methyl ester; Neofull ester; Nonadienal, e.g., nonadienal; Nonadienal 1% / TEC C; 2,6-Nonadienol; cis-6-nonenal, e.g., cis-6-nonenal 10% / TEC; cis-6-nonenol; orange leaf oil, essential oil, extract, substitute or alternative, e.g., orange leaf ECO essential oil; Paraguayan orange leaf oil; phenoxyacetaldehyde, e.g., phenoxyacetaldehyde 50; phenylacetaldehyde, e.g., phenylacetaldehyde 50% / phenylethanol; pyralone; RESEDAL; rose ether; aromatic rose ether; olein; tricyclic terpenoid aldehyde; neoprivet aldehyde; undecanetriene; methyldecenol; iononitrile, e.g., iononitrile 0.1% / TEC; iononitrile 10% / TEC; phenylacetaldehyde dimethyl acetal;

[0030] B12) At least one herbal ingredient comprising about 0.01 wt% to about 0.5 wt%, more specifically 0.01 wt% to about 0.1 wt% of the fragrance ingredients used in the fragrance composition, selected from: basil oil, essential oil, extract, substitute or alternative, such as Egyptian basil oil ORPUR; chamomile oil, essential oil, extract, substitute or alternative, such as British chamomile DQ(AC) XN 41528TT; citronellal; clary sage oil, essential oil, extract, substitute or alternative, such as clary sage oil COSMOS; French clary sage oil ORPUR; CYPRISATE; eucalyptus oil, extract, essential oil, substitute or alternative, such as Brazilian lemon eucalyptus oil; lavender oxane; pinoacetal dehyde; tanaisone; thyme oil, essential oil, extract, substitute or alternative, such as thyme red oil 40-45%; thyme white oil DQ(AC). XN 41491TT; Thymol crystals;

[0031] B13) At least one marine / aquatic fragrance ingredient, comprising about 0.01 wt% to about 5 wt%, more specifically about 0.01 wt% to about 4.3 wt%, of the fragrance ingredients used in the fragrance composition, selected from: adolphin; azurone, such as AZURONE 10% / TEC; citrulline 1951; anisealdehyde; floralozone; anthocyanin; melon aldehyde; scentenal; jasmine aldehyde; senna aldehyde;

[0032] B14) At least one peppermint ingredient comprising about 0.01 wt% to about 0.5 wt%, more specifically about 0.01 wt% to about 0.47 wt% of the flavoring ingredients used in the flavoring composition, selected from: bromelain oil, essential oil, extract, substitute or alternative, such as South African bromelain oil COSMOS; L-carvone; Asian peppermint oil, essential oil, extract, substitute or alternative, such as Asian peppermint oil (CORNMINT OIL DEMENTHOLIZED); fresh peppermintone; isomenthone DL; L-menthol; menthol-DL; menthone; menthyl acetate; peppermint oil, essential oil, extract, substitute or alternative, such as PEPPERMINTAM FAR WEST DQ AC 41624TT; PEPPERMINT AM MID WEST MIW DQ AC 41253TT; PEPPERMINTAM WILL REDIST DQ AC 24150TT; PEPPERMINT AM WILLAM NAT DQ AC 37968TT; PEPPERMINT AMER 9303 DQ (AC) 37934TT; PEPPERMINT CHINESE T'LES (EXCN) DQ24329TT; PEPPERMINT CHINESE TR (CN) DQ 24109TT; PEPPERMINT CN TERPLESS FDC DQAC 37921TT; PEPPERMINT HMF DQ 24817TT; PEPPERMINT INDIAN TPC-1 DQ AC 24049TT; PEPPERMINT OIL BLEND; PEPPERMINT PIP IND REC.FDC DQ AC 24040TT; Spearmint oil, essential oil, extract, substitute or alternative, such as Spearmint AM FW NAT DQ AC XN 41610TT; Spearmint oil USA TYPE;

[0033] B15) At least one musk component, comprising about 0.01 wt% to about 50 wt%, more specifically about 0.01 wt% to about 44.43 wt% of the fragrance components used in the fragrance composition, selected from: asterolone; cashmere; musk; cyclopentadecanolone, such as cyclopentadecanolone DQ 1% PG; musk T; galacmus; galacmus S; cyclopentadecanolone; musk ketone; protomus C14; white musk (SERENOLIDE); cyclohexadecylolone; sylkolide; cyclohexadecylone;

[0034] B16) At least one iris component, comprising about 0.01 wt% to about 10 wt% of the fragrance components used in the fragrance composition, selected from: allyl ionone; dihydro-ethyl ionone; ethyl ionone; methyl ionone; pure ionone; isomethyl ionone 70; isomethyl ionone 95; irisone;

[0035] B17) At least one spice component comprising about 0.01 wt% to about 1 wt%, more specifically about 0.01 wt% to about 0.45 wt% of the spice components used in the spice composition, selected from: cardamom oil, essential oil, extract, substitute or alternative, such as cardamom seed oil ORPUR; cardamom substitute 1527 F; cardamom substitute 1527 F / 2; caryophyllene; cinnamyl alcohol; cinnamyl alcohol; cinnamaldehyde; cinnamon leaf oil, essential oil, extract, substitute or alternative, such as washed cinnamon leaf oil ORPUR; clove oil, essential oil, extract, substitute or alternative, such as clove bud oil; colorless clove leaf oil; refined clove leaf oil RB COSMOS; coriander oil, essential oil, extract, substitute or alternative, such as coriander seed oil ORPUR. COSMOS; elemenine oil, essential oil, extract, substitute or alternative, e.g., elemenine resin 50% / BB; ethyl cinnamate; eugenol; ginger oil, essential oil, extract, substitute or alternative, e.g., Indian ginger oil ORPUR; fresh ginger root slices; isoeugenol; methyl cinnamate; methyl isoeugenol; MYSTIKAL; nutmeg oil, essential oil, extract, substitute or alternative, e.g., Indonesian nutmeg oil; pepper oil, essential oil, extract, substitute or alternative, e.g., Madagascar black pepper oil ORPUR; Sichuan pepper (ASH BARK) DQ AF 24070TT;

[0036] B18) At least one sulfur-containing component, comprising about 0.01 wt% to about 0.5 wt%, more specifically about 0.01 wt% to about 0.21 wt% of the fragrance ingredients used in the fragrance composition, selected from: Anjeruk, e.g., ANJERUK 0.01% / TEC; Corps cassis, e.g., CORPS CASSIS 0.1% / TEC; CORPS CASSIS 10% / TEC; Corps pamplemousse, e.g., CORPS PAMPLEMOUSSE PURE 1% / TEC; CORPS PAMPLEMOUSSEPURE 10% / TEC; dimethyl sulfide, e.g., dimethyl sulfide; dimethyl sulfide 1% / TEC; cyclic amine (GARDAMIDE); rapin, e.g., rapin 1% / IPM-TEC; thiol compounds, e.g., mercapto-8-menthene-1 PARA 0.1% IN TEC; Methylisopropylthiazole; Nardozeste oil, essential oil, extract, substitute or alternative, such as NARDOZESTE ABQ5031; NEOCASPIRENE EXTRA; Nolanylamine 1% triacetin; Oxane, such as Oxane 50% / TEC; Fruit amide; Paramenthone, such as Paramenthone 1% / TEC;

[0037] B19) At least one sweet / powdery fragrance component, comprising about 0.01 wt% to about 10 wt%, more specifically about 0.2 wt% to about 7.83 wt%, of the fragrance components used in the fragrance composition, selected from: acetophenone; aubepine paracresol; dicyclononalactone; coumarin; ethyl lactone, such as ethyl lactone 1% / TEC; ethyl vanillin; jasmine aldehyde vanilla oil, essential oil, extract, substitute or alternative, such as vanilla absolute 20 FOLD DQ AC41493TT; vanilla S / ABS DEC 50% PG AAF0517 L228655; vanilla SUP ABS DEC DQ P17 SBAC 41561TT; vanilla DQ (AF) 41319TT; vanillin; vanillin DQ (AF) 41320TT; Vanolia Oil, essential oil, extract, substitute or alternative, such as VANOLIA fragrance base ABF0303B; veratraldehyde (VERATRIC ALDEHYDE);

[0038] B20) comprises, in about 0.01 wt% to about 15 wt%, more specifically about 0.01 wt% to about 10.37 wt%, of at least one woody / rosin component selected from: borneol; borneol acetate liquid; p-butylcyclohexanol; p-butylcyclohexyl acetate; cedarwood oil, essential oil, extract, substitute or alternative, such as Virginia cedarwood oil ORPUR; fennelol; ebony alcohol; synthetic oakmoss; fennel acetate; guaiac oil, essential oil, extract, substitute or alternative, such as Paraguayan guaiac oil; isononyl acetate; Java sandalwood; gentamicin; dihydrorosinyl acetate (MENTHANYL) ACETATE; methyl cedryl ketone; nobutyl acetate; spironolactone; oxyoctalineformate; patchouli oil, essential oil, extract, substitute or alternative, such as Indonesian colorless patchouli oil; Indonesian iron-free patchouli oil (COSMOS); methyl-pinene; ethyl-pinene; santalol; super santalol; turpentine oil, essential oil, extract, substitute or alternative, such as refined turpentine oil; superior grade methyl cedryl ketone; vetiver oil, essential oil, extract, substitute or alternative, such as Haitian vetiver oil (ORPUR ORGANIC COSMOS);

[0039] and optional

[0040] B21) At least one component comprising about 0.01 wt% to about 10 wt% of the fragrance ingredients used in the fragrance composition, selected from: C12 aldehyde (dodecanoic acid; menthyl acetate);

[0041] When generic names are used to describe the aforementioned useful flavoring ingredients, a skilled flavor maker will understand that these are names commonly used by flavor makers. However, a skilled flavor maker will also understand that these ingredients can be identified through other common synonyms, CAS registry numbers, or more formal nomenclature such as IUPAC nomenclature. Furthermore, a skilled flavor maker will be familiar with these additional common synonyms and more formal nomenclature, or at least know standard reference books, such as The Good Scent Company website, which contains a comprehensive list of generic names, registry numbers, and more formal nomenclatures for flavoring ingredients included in a flavor maker's palette.

[0042] The fragrance composition of the present invention may consist entirely of the fragrance ingredients described above. These fragrance ingredients may be referred to as "functional fragrance ingredients." Alternatively, the functional fragrance ingredients may form only a portion of the fragrance composition.

[0043] In one specific embodiment of the invention, the fragrance component accounts for 0.1 wt% to 100 wt%, more specifically 8.5 wt% to 100 wt%, and still more specifically 34 wt% to 71 wt% of the fragrance composition.

[0044] In addition to the functional flavoring ingredients described above, the flavoring compositions of the present invention may also contain other flavoring ingredients. A comprehensive list of other suitable flavoring ingredients can be found in the flavoring literature, such as "Perfume & Flavor Chemicals," S. Arctander (Allured Publishing, 1994) and subsequent editions of that work, which are incorporated herein by reference.

[0045] The fragrance compositions of the present invention may contain other non-fragrance ingredients. In particular, ingredients or excipients that are typically used in combination with fragrances in fragrance compositions, such as carrier materials and other auxiliaries commonly used in the art, such as solvents, such as dipropylene glycol (DPG), isopropyl myristate (IPM), benzyl acetate (BA), propylene glycol (PG), and triethyl citrate (TEC).

[0046] The fragrance compositions of the present invention can be present in the form of free oil, or they can be encapsulated. Several encapsulation media are known in the art for encapsulating fragrance formulations, and all of them are suitable for the present invention. Specific encapsulation media include microcapsules formed from amino plastic resins, such as melamine-formaldehyde resin, polyurea, polyamide, and copolymers of acrylic acid, methacrylic acid, and their esters.

[0047] The fragrance compositions of the present invention can be used to impart a desired odor impression on various forms of consumer products. However, they are preferably incorporated into consumer products used by consumers during sleep or in preparation for sleep, or placed in close proximity to the consumer while they sleep. More specifically, the fragrance compositions of the present invention can be used in laundry care products, personal care products for treating the hair and skin of human subjects, oral care products, and air care products.

[0048] Therefore, in another aspect of the invention, consumer products comprising a flavoring composition as defined herein are provided.

[0049] In one specific aspect of the invention, the consumer product is a laundry care product. Laundry care products include powdered and liquid detergents and fabric softeners, stain removers and pre-wash treatments, conditioners and softeners (including standard and concentrated conditioners, softeners and desiccant sheets); laundry aids (including stain removers, ironing aids, bleaches and color care products and other auxiliary fabric care products); laundry detergents (including machine wash liquid detergents, other machine wash detergents (including powders, capsules and tablets) and hand sanitizers (powders, flakes and cakes / sticks)); tablet sprays; clothing sprays; clothing fragrances; desiccant sachets; fragrance sachets; desiccant tablets; laundry soap; laundry detergents; gourmet detergents; ironing sprays; starch; fragrance tablets; pillow mists; drawer liners; cedar closet spray; linen water and refills, and combinations thereof.

[0050] Laundry care products contain active cleaning ingredients. Active cleaning ingredients are substances that play an active role in the washing process. These active cleaning ingredients include, but are not limited to, detergency surfactants (anionic, nonionic, cationic, amphoteric, and amphoteric surfactants), extenders (inorganic and organic extender substances), bleach, bleach activators, bleach stabilizers, bleach catalysts, enzymes, soil-suspended or dispersed polymers, chelating agents, or combinations thereof, but are not limited to these groups of substances.

[0051] Laundry care products may contain stain-removing polymers, antioxidants, colorants, preservatives, optical brighteners, opacifiers, stabilizers such as guar gum and polyethylene glycol, anti-shrinkage agents, anti-wrinkle agents, stain removers, fabric embrittlement agents, reducing agents, spotting agents, bactericides, fungicides, corrosion inhibitors, defoamers, and one or more color-correcting dyes.

[0052] Laundry care products may contain fabric-softening active ingredients. Non-limiting examples include silicones, fatty acids, fatty esters, polyglycerol esters, polyethylene waxes, sucrose esters, clays, triglycerides, cationic starches, and cationic polymers.

[0053] In another aspect of the invention, the consumer products are personal care products. Personal care products include soaps, shower gels, body lotions, moisturizers, deodorant sprays, perfumes, cosmetics, floating bath oils, aftershaves, creams, emulsions, deodorants (including stick deodorants), pre-electric shave lotions, aftershave washes, antiperspirants, shampoos, conditioning agents, and rinses, as well as related products, including skin care products, eye cosmetics, bath liquids, protective skin preparations, lipsticks, lip balms, after-bath splashes, and pre-sun and sun products (including sunscreens). In fact, any chemical product that comes into contact with hair or skin and may include one or more of the compositions of the present invention in an effective amount or concentration can be considered a personal care product of the present invention.

[0054] In another specific aspect of the invention, the consumer product is an oral care product. Oral care products include toothpaste, dental cream, gels or powders, odontic products, oral washes including stain-removing liquids, typically comprising a water / alcohol solution, humectants, sweeteners, foaming agents, colorants, and optional enzymes; pre- or post-brushing rinse preparations, chewing gum, lozenges, and candies. Toothpaste and dental gels typically comprise abrasive and polishing materials, foaming agents, flavoring agents, humectants, binders, thickeners, sweeteners, whitening / bleaching / stain removers, water, and optional enzymes.

[0055] In another specific aspect of the invention, the consumer product is an air care product. Air care products include candles, air freshener devices such as liquid-electro-air freshener devices, aerosols, pump-operated sprays, scented candles, membrane permeation devices, liquid wick devices, oil-based gel fragrances, and hydrogels.

[0056] Air care products may contain one or more fragrance ingredients having a vapor pressure of less than 0.01 mmHg at 25 degrees Celsius. Suitable fragrance ingredients are listed in S. Arctander, “Perfume and Flavor Chemicals: Volume 1, Allured Publishing Corporation 1969 or any subsequent edition thereof, as well as in the IFRA (International Fragrance Research Association) database and the RIFM (Research Institute of Fragrance Materials) database, the entire contents of which are incorporated herein by reference.

[0057] In addition, air care products may contain one or more low vapor pressure solvents or carriers to assist in the evaporation of the fragrance ingredients mentioned above.

[0058] Low vapor pressure solvents are defined herein as organic solvents having a vapor pressure of less than 0.1 mmHg at 20°C, and are included in the category of so-called LVPVOCs (Low Vapor Pressure Volatile Organic Compounds) approved by the California Air Resources Board (CARB). Examples of low vapor pressure solvents include dipropylene glycol methyl ether acetate (DPMA), available under the trade name Dowanol® DPMA; Dowanol TPM (ditripropylene glycol methyl ether); Dowanol DPNB (propylene glycol n-butyl ether); Dowanol DPNP (propylene glycol n-propyl ether); and other suitable DowChemical Dow P series glycol ethers.

[0059] Based on the total weight of the fragrance composition used in the air care product, the low vapor pressure solvent may be present in an amount of 10% or more, more preferably 20% or more, and more specifically 30% or more. Based on the total weight of the composition used in the air care product, the upper limit of the low vapor pressure solvent may be up to 60%, more specifically up to 70%, and still more particularly up to 80%.

[0060] In addition to or instead of the low vapor pressure solvents described above, the fragrance compositions of the present invention may contain one or more fragrance ingredients having similar evaporation properties to those listed in the CARB VOCs above. Suitable fragrance ingredients are those (and their equivalents) described in EP2328625, which is incorporated herein as a so-called “FPC” ingredient. FPC ingredients include, but are not limited to, isononyl acetate, dihydromyrcenol, linalool, geraniol, d-limonene, and benzyl acetate.

[0061] The fragrance composition may additionally include a carrier material consisting of one or more volatile aromatic chemicals. Volatile aromatic chemicals are defined as a group of fragrance components that are highly volatile, for example, having a vapor pressure of 0.1 mmHg or higher at 25 degrees Celsius, more specifically at least about 0.2 mmHg or at least about 0.5 mmHg or at least 1 mmHg.

[0062] Exemplary volatile aromatic chemicals include hexyl acetate, 3,3,5-trimethylhexyl acetate, borneol formate, 3-hexenyl butyrate, phenethyl acetal, butyl hexanoate, isononol, acetone alcohol, isopentenyl acetate, isobutyl 2-pentanoate, pentyl propionate, herbal dioxane, furfuryl formate, methyl acetylacetone, and butyl acetoacetate.

[0063] Other volatile aromatic chemicals are selected from any of the compounds listed in Table 1 of US 8,603,963, which are incorporated herein by reference.

[0064] In addition to the materials listed above, the compositions of the present invention may also contain one or more surfactants selected from agents that provide fabric conditioning or softening, fabric freshening, air freshening or deodorizing, and odor removal. Surfactants may also include surfactants, emulsifiers, solubilizers, polymers, odor-resistant agents, buffers, zinc ions, etc.

[0065] Air care devices suitable for the compositions of the present invention include electric air purifiers, which refer to devices or systems that incorporate electrical or battery power. The term "electric air purifier" includes heated liquid wick systems, piezoelectric spray systems, liquid flow measuring devices, and devices powered by solar energy or other alternative forms of energy.

[0066] Devices of any suitable size, shape, form, or configuration may be used. Suitable devices may be made of any suitable material, including but not limited to: natural materials, artificial materials, fibrous materials, non-fibrous materials, porous materials, non-porous materials, and combinations thereof.

[0067] In some embodiments, a typical device utilizes a combination of a core and a dispensing surface to dispense a liquid composition in a liquid composition reservoir.

[0068] Devices for dispensing volatile liquids into the atmosphere (e.g., "wicking devices") are known, such as fragrances, deodorants, disinfectants, or pesticide active agents. Typical air care devices utilize a combination of a wick and a radiating surface to dispense volatile liquids from a liquid reservoir. The device should be designed to allow the liquid composition to be dispensed into the ambient atmosphere at a stable and controlled rate, while maintaining consistent olfactory characteristics throughout the device's lifespan.

[0069] In one embodiment of the invention, the device includes an electrically or battery-operated energy source, comprising a heated liquid wick delivery system, a piezoelectric spray system, an electrospray device, or a liquid flow measuring device. Commercial examples of electrically powered liquid air care devices include, but are not limited to, Glade® PlugIns® fragrance oils sold by SC Johnson & Sons and Air Wick and Air Wick X-Press® fragrance oils sold by Reckitt Benckiser; Febreze Noticeables sold by Proctor & Gamble Co.; Electric HomeAir Fresheners sold by Yankee Candle Co.; and Renuzit fragrance oils sold by Henkel AG.

[0070] The spice composition of the present invention can be used as a spice that can be prepared from all the types of spice blending devices described above.

[0071] The fragrance compositions of the present invention are evaporated in a controlled manner. Specifically, the evaporation rate, measured at 0.2-0.6 g / day per unit time relative to the weight loss of fragrance, is relatively constant within a specified time period (e.g., 30, 40, or 60 days). The evaporation rate is substantially constant, for example, the difference in fragrance weight loss per unit time within the specified time period is less than ±5%, ±10%, or ±20%.

[0072] Furthermore, the evaporation rate is such that the reservoir containing the liquid composition of the present invention is empty, or substantially empty, before the rate decays to below 0.2 g / day.

[0073] The level at which a fragrance composition is incorporated into a consumer product can vary widely and depends to some extent on the specific application and consumer product. In liquid electro-air care devices, for example, the entire composition to be evaporated typically consists of a fragrance composition.

[0074] Based on the total weight of the consumer product, the incorporation of the flavoring composition ranges from about 1 wt% to about 100 wt%, more specifically from about 1 wt% to 60 wt%, and still more particularly from about 0.01 wt% to 25 wt%.

[0075] In one specific embodiment of the invention, the fragrance composition for use in an air freshener composition comprises about 0.01 wt% to 25 wt% of a functional fragrance ingredient based on the weight of the air freshener composition.

[0076] In another specific embodiment, the fragrance composition for use in an oral care composition comprises about 0.01 wt% to about 60 wt% of a functional fragrance ingredient based on the weight of the oral care composition.

[0077] In another specific embodiment, the fragrance composition for the fabric care composition comprises about 0.01 wt% to about 20 wt% of a functional fragrance ingredient based on the weight of the fabric care composition.

[0078] In another specific embodiment, the fragrance composition for use in a personal care composition comprises about 0.01 wt% to about 20 wt% of a functional fragrance ingredient based on the weight of the personal care composition.

[0079] In another specific aspect of the invention, the consumer product is a household care product. Household care products are specifically designed for cleaning, rinsing, caring for, or treating industrial, domestic, or public hard surfaces and textile surfaces; their purpose is to impart beneficial properties to the treated surface, such as water resistance, dirt release, stain resistance, anti-fogging, surface repair, wrinkle resistance, gloss, lubrication, and / or improvement of the residue, effect, or efficacy of the active substances contained in the active ingredients of the composition. Therefore, the household care compositions of the present invention include: surface cleaning compositions (e.g., glass, floors, countertops, bathrooms, toilet bowls, sinks, appliances, and furniture cleaning compositions); disinfectants (e.g., sprays and solid air disinfectants (including gels); sprays, solids, liquids, and pastes of surface disinfectants); waxes and other surface protection and / or polishing compositions; and carpet shampoos. Household care compositions may include additional ingredients such as enzymes, bleach, brighteners, color care agents, fabric softeners, antifoaming agents, dispersants, dye transfer inhibitors, chelating agents, aerosol sprays, gelling agents, thickeners, and combinations thereof.

[0080] In another specific embodiment, the fragrance composition for use in a home care composition comprises about 0.01 wt% to about 34 wt% of a functional fragrance ingredient based on the weight of the home care composition.

[0081] The fragrance compositions of the present invention are designed according to fragrance manufacturing rules for addressing sleep quality, and provide performance and desired pleasure consistency suitable for specific consumer product applications. More specifically, the fragrance compositions are selected from combinations of functional fragrance ingredients, and based on the SC values ​​of those ingredient combinations.

[0082] Therefore, in another aspect of the invention, a method for preparing a fragrance composition for improving sleep quality is provided, the method comprising the step of combining functional fragrance ingredients in such a manner that the composition has a Sandman classification value greater than 1.35.

[0083] In another aspect of the invention, a method for preparing a consumer product is provided, the method comprising incorporating a fragrance composition having a known Sandman classification value greater than 1.35, as defined herein, into a consumer product matrix.

[0084] The applicant has conducted extensive research on the relationship between fragrance compositions and sleep quality in human subjects who inhaled the compositions. The research employed consumer testing and electroencephalography (EEG) to measure brain activity and to statistically analyze the resulting data. In this manner, the applicant has elucidated a new parameter that enables fragrance manufacturers to objectively design high-performance and complex fragrance compositions that positively influence sleep quality.

[0085] The applicant now provides further examples of the invention with reference to the embodiments and detailed descriptions of EEG and consumer testing methods.

[0086] Sandman classification (SC) scores were determined using electroencephalography (EEG) with a standard 10-20 electrode system.

[0087] The 10-20 system is a well-known, standardized method for describing and applying scalp electrode placements associated with subcortical regions of the brain. A detailed description is not required here, and the applicant merely draws attention to Jasper HH., the 10-20 electrode system of the International Federation. Electroencephalogr Clin Neurophysiol 1958;10:371-375, which is incorporated herein by reference.

[0088] Twenty-five female participants (aged 32-52) participated in this study. All participants gave informed consent to participate in this test.

[0089] Fragrance compositions were prepared by aspirating 0.1 g of fragrance oil into a sorborod and allowing it to stand for 24 hours. Five fragrance compositions were included for comparison in this test, excluding one odorless control (blank sorborod). Each composition was served once during the test. The order in which the fragrance compositions were served was balanced with the participants.

[0090] The test consisted of two elements, repeated multiple times throughout the experiment: the first element comprised an alert / active task, and the second element comprised a relaxation task. For the alert / active task, participants performed a short 2-minute math task to ensure they were alert. Following this 2-minute math lesson, participants then performed the relaxation task. During the relaxation task, EEG was recorded as participants sat comfortably while wearing blindfolds to eliminate unwanted visual stimuli (e.g., from the sorborod). Participants were instructed at the start of the experiment to close their eyes and sit awake, but remain relaxed to avoid unnecessary movement / muscle tension and continue normal breathing. Immediately after participants closed their eyes, a spice composition was presented to them using sorborods fixed approximately 5–6 cm below the nose. The spice composition was held under the nose for 5 minutes. At the end of the 5 minutes, participants opened their eyes and completed a questionnaire that included ratings about their mood and the scent. Afterward, participants again performed the alert math task, followed by the relaxation task, and then the next spice composition was presented. This test was repeated for all spice compositions. Each spice composition / sorbarod (4 compositions and 1 odorless blank) was presented twice during the task, meaning that participants completed a total of 10 math tasks and 10 relaxation tasks.

[0091] In each experiment, Ag / AgCl electrodes, positioned according to the 10-20 international system (AEEGS, 1991) and mounted on an EasyCap, were used to record EEG using NuAmp amplifiers (Neuroscan, El Paso, TX) from 18 scalp sites. The spliced ​​images included four midline sites (FZ, FCZ, CZ, PZ) and seven sites on each hemisphere (FP1 / FP2, F3 / F4, FC3 / FC4, C3 / C4, CP3 / CP4, P3 / P4, O1 / O2). Additional electrodes were used as ground and reference sites. The correct mastoid process (behind the ear) was used as the active reference. Data were then re-compared offline to the algebraic mean of the right and left mastoid processes. Respiratory signals were simultaneously recorded using piezoelectric sensors embedded in the abdominal breathing band. EEG signals were digitized at a sampling rate of 1000 Hz. Data were recorded using a 300 Hz low-pass filter, but without a high-pass filter (DC). During the experiment, digital codes were sent to an EEG recording computer to label the presentation of odor stimuli.

[0092] For each experiment, EEG data were filtered offline using a bandpass filter of 1–50 Hz. Digital codes were used to mark the time of odor stimulus presentation (during exhalation), and then the codes were timed to coincide with the start of the next breath using markers from the respiratory band traces. This ensured that all odor stimuli were timely and consistent throughout the experiment, and coincided with the start of the next breath. EEG recordings were taken within the time window of odor presentation. Excessive noise or drift (+ / - 50 Hz) was excluded. Measurement intervals for V) were rejected. Furthermore, all tests were visually inspected for minor artifacts and drifts, and discarded if necessary.

[0093] Following methods generally known in the art, Fast Fourier Transform (FFT) analysis was used to analyze data from the time window of interest (presented every 5 minutes of spice / sorbarod) in the frequency domain. The FFT analysis converted the EEG signal into an energy spectrum, where the X-axis reflects frequency (Hz) and the Y-axis reflects power (power reflects the amplitude of each frequency within the time window and the relative amount of those waves, i.e., how long a specific frequency of each waveform exists within the window). The main frequency band used in this experiment is... The band (8-12Hz) is pre-associated with relaxation.

[0094] Frequency analysis was performed on each participant for each fragrance condition (averaging the results of two replicates). The data from the entire group of participants were then averaged to generate the average spectrum for each fragrance condition. Spectral responses were compared between the fragrance and unfragrant conditions, and among the individual fragrance conditions. Then, specific frequency bands of interest were analyzed. A statistical analysis (ANOVA) was performed on the samples to test for significant differences between conditions. Analyses were performed in different brain regions to examine more specific effects through the frontal and posterior regions.

[0095] The results of sleep research were validated using EEG test data to determine whether the EEG data were relevant to actual sleep experience.

[0096] Initially, 70 women aged 25–60 years were pre-screened for suitability and eligibility using a predefined questionnaire. Twenty participants (aged 34–56 years) were selected based on negotiated criteria, including sleep performance, lifestyle, nighttime routines, general health, and aroma allergies. All participants gave informed consent before participation. Participants were selected based on average or below-average sleep quality (i.e., neither poor nor very poor sleep). Participants were instructed to maintain their usual sleep habits and nighttime routines and avoid excessive alcohol consumption throughout the study.

[0097] Different test fragrance compositions were selected for this study. The environmental strength of the compositions was based on an average of 10.5 m. 2The selection was based on a standard bedroom size and a wide range of guidelines for nighttime use. An ambient fragrance was provided in the room using a Reed diffuser device containing 7 rattan sticks (20% fragrance, 50g filler volume). When screening volunteers, bedroom size and whether the volunteer slept with the bedroom door and windows open or closed were taken into consideration. For the unscented diffuser (control), a mixture of DPM and DPG was used. Participants were instructed to place the Reed diffuser near the bed (e.g., on a dresser / drawer) rather than on the bedside table (to avoid accidental placement).

[0098] The study lasted for two weeks for each participant. Each week, participants were provided with a Reed fragrance diffuser containing either a fragrance test composition or a control liquid. Participants were informed that they would be tested with two fragrance samples, the intensity of which could vary, and that one of the diffusers was not explicitly stated to be fragrance-free. During week 1, participants slept with the control diffuser in the presence to measure baseline sleep quality (control week). During the second week, participants slept with the fragrance composition in the presence. The allocation of fragrance and unfragrant conditions in weeks 1 and 2 was coordinated and balanced among participants.

[0099] Participants were provided with information on how to use the reed diffuser. Participants simply needed to set up the diffuser at the agreed location at the beginning of each week and replace / remove the diffuser at the end of each week.

[0100] Participants were provided with a 7-question sleep diary each week. Participants wore the activity tracker every night as instructed. They completed the sleep diary 15 minutes after waking up each morning. The diary included questions about sleep quality and quantity, as well as questions about scent awareness. At the end of the 2-week test, participants were interviewed and reported on their experiences during the test.

[0101] Twenty participants recorded their sleep diaries daily using a sleep diary questionnaire. Sleep diary measures included those related to sleep quality (sleep quality score, morning wakefulness score) and sleep volume (sleep duration, expected sleep time, estimated number of awakenings). These measures are established sleep parameters and can be sensitive to differences in sleep performance.

[0102] Sleep quality scores were recorded daily by participants: Last night I slept: Very good (= 5)...Good (= 4)...Fairly good (= 3)...Fairly bad (= 2)...Very bad (= 1). Therefore, higher scores were associated with better sleep quality. Average questionnaire results for each test week showed that participants reported significantly better sleep in the presence of fragrance compared to the unfragranted control group (p=0.002).

[0103] Participants also noted in their sleep diaries how alert they felt 15 minutes after waking up: 15 minutes after waking up, I felt: very alert (= 5)... alert (= 4)... not alert (= 3)... tired (= 2)... extremely tired (= 1). Therefore, higher values ​​were associated with participants feeling more alert as the first thing in the morning. Average results per test week showed that participants reported feeling more alert as the first thing in the morning after sleep compared to the unflavored control group (p=0.022).

[0104] In their daily sleep diaries, participants recorded their estimated time to fall asleep: for example, "As far as I remember, it took me... minutes to fall asleep." Weekly average results showed that participants perceived that they took significantly less time to fall asleep in the presence of the flavoring composition compared to the unflavored control group (p=0.043).

[0105] Participants also recorded the estimated number of times they woke up at night in their diaries: for example, "I remember waking up... times last night." Weekly average results showed that, compared with the unscented control group, participants reported a significantly reduced number of frequent awakenings during sleep in the presence of the fragrance composition (p=0.02).

[0106] Mean sleep duration was calculated based on participants' perceived expected time to fall asleep (time taken to fall asleep after lights out) and time of wakefulness in the morning. The average duration was then taken over the week. Results showed no significant difference in self-reported sleep duration between the spice composition week (7 hours 29 minutes) and the control week (7 hours 36 minutes) (p=0.5).

[0107] Use the Philips Actiwatch® to monitor nighttime sleep quality. The device, worn by the participant, is small and lightweight, similar to a wristwatch. The Actiwatch® is strapped to the non-dominant wrist each night and removed upon waking the next morning. Participants can press a small "event marker" button to indicate "falling asleep" and "waking up in the morning." The Actiwatch® records body movements during sleep at 30-second intervals. The activity tracking module includes implementations of activity tracking devices manufactured by: ActiGraph LLC, ActiTrainer (formerly CSA / MTI), Ambulatory Monitoring Inc., Motionlogger Actigraph, Cambridge Neurotechnology Actiwatch, Consultoria Eletronica Four Parameter Brazilian Actigraph, GulfCoast Data Concepts USB Accelerometer, MetriSense, Inc. – a distributor of activity monitors from CamNtech, Ltd., UK, PAL Technologies Ltd – and a manufacturer of activity monitors, Philips Respironics Actiwatch.

[0108] Three parameters were analyzed from Actiwatch® records: sleep efficiency (an overall measure of sleep quality), wake-up time (calculated based on the total number of wake-ups during the night, including the time required to fall asleep), and the percentage of time spent awakening during the night relative to the time spent falling asleep. All three measurements were based on validated software algorithms and are well-established measurements used in sleep research.

[0109] Sleep efficiency scores were calculated using the built-in algorithm in Actiware software. Efficiency scores were assigned to each participant nightly and compared using ANOVA (subject-, condition-, week-, day-factor) over two test weeks. Data showed a strong trend towards higher sleep efficiency scores in the presence of ambient fragrance compared to the control week, although the percentage of participants who scored higher did not reach statistical significance (p=0.080).

[0110] Two additional parameters recorded by Actiwatch® were wake-up time (in minutes) and the percentage of time spent awake during the night (relative to the time spent sleeping). Scores for each parameter were calculated for each night and for each participant, and comparisons were made using ANOVA over two test weeks. The wake-up time analysis showed a strong trend of reduced nighttime awakenings in the presence of ambient scents compared to the control week. However, this did not reach significance at the 95% level (p=0.1).

[0111] This result was supported by analyzing the percentage of awake time relative to sleep time. Statistical analysis of the percentage of nighttime awakenings compared to sleep showed that participants who fell asleep in the presence of ambient fragrances had fewer awakenings during nights compared to unscented control nights. However, this did not reach the 95% significance level (p=0.078).

[0112] Further analysis was conducted to determine whether the objective measurements of sleep recorded by the activity recorder were consistent with the self-reported responses recorded in the daily sleep diary (data with and without added fragrance were combined).

[0113] A correlation analysis was conducted between sleep quality scores recorded in daily sleep diaries and objective parameters recorded by a motion tracker. The results showed a significant correlation between self-reported sleep quality levels (diary) and sleep efficiency (motion tracker) (p=0.005). Better sleep quality scores from the diary were associated with higher sleep efficiency scores. This suggests a good consistency between sleep quality scores reported by participants in their daily sleep diaries and objective measurements of sleep quality monitored by the motion tracker.

[0114] Similarly, a correlation analysis was conducted between the wakefulness rating recorded in daily sleep diaries and the objective parameters recorded by the activity tracker. Visual observation of the results suggested that wakefulness (diary) and sleep efficiency rating (activity tracker) were roughly consistent across participants, although this was not significant (p=N / S). This suggests that the effect of wakefulness on wakefulness scores is not as effective as that of sleep quality scores in terms of consistency with activity tracker data.

[0115] The present invention will now be described in more detail with reference to embodiments and experimental examples. However, it should be understood that these embodiments are for illustrative purposes only and should not be construed as limiting the scope of the invention.

[0116] Example

[0117] The fragrance compositions detailed in Table 1 were prepared and subjected to various test protocols. Those fragrances labeled as Fragrance 41 (= Example - Fragrance 4) and Fragrance 47 (= Example - Fragrance 6) are fragrance compositions of the present invention, while those fragrances labeled as Fragrance 44 (Example - Fragrance 1) and Fragrance 37 are comparative examples that do not meet the conditions of the present invention, but do not violate the guidance values ​​of the specific odor families that have been highlighted.

[0118]

[0119]

[0120] Table 1

[0121] The range (minimum and maximum) values ​​of the tested spices are compared to the range values ​​of the "Good Sleep" spices. (In bold) Italic The cells with numbers indicate violations of the recommended range. The last row details the recommended outcome (yes or no), specifically whether the spice was considered to have sleep-enhancing properties.

[0122] Compare Example-Flavor-1 with Examples-Flavor-2, Example-Flavor-3, Example-Flavor-4, Example-Flavor-5, Example-Flavor-6 and Example-Flavor-7.

[0123] As an example of the above summary, the spices identified by EEG yielded the following results:

[0124]

[0125] Table 2

[0126] Sandman classification and verification measurements for testing spices

[0127] Verification measurement value = Sleep % + (Sleep quality)²

[0128] Sleep % is a measurement derived from the algorithm in the activity log check and is an overall measurement of sleep quality, while sleep quality is a subjective measurement with a value of 1-5.

[0129] By directly comparing the Sandman classification value of Example-Flavor-1 with the equivalent values ​​of any of Example-Flavor-2, Example-Flavor-3, Example-Flavor-4, Example-Flavor-5, Example-Flavor-6, or Example-Flavor-7, we observed that Example-Flavor-1 has a lower Sandman classification value than any other fragrance. Furthermore, the Sandman classification value of Example-Flavor-1 is below a specified threshold of 1.35. Therefore, we can predict that Example-Flavor-1 will significantly enhance sleep worse than any other fragrance. Indeed, our validation measurements demonstrate this result.

[0130] The present invention also specifically includes the following technical solutions:

[0131] 1. A flavoring composition comprising at least two, more specifically at least five, still more specifically ten or more flavoring ingredients having a known Sandman classification (SC) value of at least 1.35.

[0132] 2. The fragrance composition of claim 1, wherein the fragrance component with a known SC value accounts for 0.1 wt% to 100 wt% of the fragrance composition, more specifically 8.5 wt% to 100 wt%, and still more specifically 34 wt% to 71 wt%.

[0133] 3. The fragrance composition according to claim 1 or 2, comprising at least 0.01% by weight of a fragrance material selected from the group consisting of:

[0134] A) At least one citrus component, particularly selected from the group consisting of about 1 wt% to about 30 wt%, more specifically about 1.2 wt% to 28.9 wt%, of the total amount of flavoring ingredients used in the flavoring composition:

[0135] Bergamot oil, essential oil, extract, fragrance base, substitutes or alternatives, such as Italian pressed bergamot oil; Bergamot REC ABX5638; Bergamot fragrance base 104 / 4; Citrile; Citral TECH; Citral diethyl acetal R; Citronellol; Cypermethrin; Dihydromyrcenol; Dimethyloctenone; 2,6-Dimethylheptanol; Fropi; Grapefruit oil, essential oil, extract, substitutes or alternatives, such as ultra-concentrated grapefruit juice 7108A or grapefruit oil COSMOS; Lemon oil, essential oil, extract, fragrance base, substitutes or alternatives, such as distilled pure California lemon oil; Italian lemon oil ORPUR COSMOS; Reconstituted lemon oil 1385; Spanish lemon DQ (AC) XN 41482TT; Citrin; Linalool Oxide; Synthetic Linaloyl Acetate; Litsea cubeba oil, essential oil, extract, substitute or alternative, such as Chinese Litsea cubeba oil; Orange oil, essential oil, extract, fragrance base, substitute or alternative, such as MANDARIN ARTESSENCE OIL; Brazilian Fresh Orange Oil ORPUR; Italian Colorless Orange Oil MDORPUR; Washed Orange Oil COSMOS; Mandarin Orange 32048 SAE; Mandarin Orange 32048 SAE / 2; Mandarin Orange MATCH CF; Chrysodium Methane; Myrcene 90; Orange Oil, essential oil, extract, fragrance base, substitute or alternative, such as Orange 49; Orange Aldehyde; California Orange DQ (AC) XN 41228TT; Brazilian Orange Oil; Colorless Orange Oil NS; Florida Orange Oil; SAVON Concentrated Orange Oil (ORANGE SAVON CONC) OIL); Orange (ORANGETERPENELESS) DQ (AC) 41483TT; Distilled Orange Terpenes; Orange Leaf Oil, Essential Oil, Extract, Flavor Base, Substitute or Substitute, e.g., Orange Leaf Oil ORPUR; Cyclocarya Aldehyde B; Isoprene Acetate; Cyclocarya Ether; Tamarind Oil, Essential Oil, Extract, Flavor Base, Substitute or Substitute, e.g., Tamarind AB8212; Mandarin Oil, Essential Oil, Extract, Flavor Base, Substitute or Substitute, e.g., South African Mandarin DQ AC XN41957TT; Terpinene; Isorpinene; and Terpinene Acetate;

[0136] And at least one of at least five ingredients from groups B1-B20, in the amounts shown:

[0137] B1) At least one aldehyde fragrance component comprising about 0.01 wt% to about 1.5 wt%, more specifically about 0.01 wt% to about 1.41 wt% of the fragrance components used in the fragrance composition, selected from: decanal; undecenal; undecenal; lauraldehyde; methyl nonanal; octanal; isononanal; nonanal; nonenal 1% / TEC; C12 aldehyde (dodecanal); isoundecenal; saffron aldehydes, such as saffron 10% / TEC; trans-4-decenal, such as decenal-4-trans, decenal-4-trans 10% / TEC; dihydrofaryl; dodecanal, such as dodecanal 10% / TEC; MYRALDENE; and saffron ester;

[0138] B2) At least one amber component comprising about 0.01 wt% to about 25 wt%, more specifically about 0.01 wt% to about 22.49 wt% of the fragrance components used in the fragrance composition, selected from: ambergris acetal, such as ambergris acetal 1% / TEC; ambergris acetal IPM; Ambermax, such as AMBERMAX 10% / TEC, AMBERMAX 50% / DOWANOL TPM; imperial ambergris, such as imperial ambergris 10% / DPG; ambergris furan; ambergris furan tablets; Belambre, such as BELAMBRE 50% / IPM; ethoxymethoxycyclododecane; cedrol acetate liquid; cedrol methyl ether; super ambergris ether; ambergris ketone; carrageenan; KEPHALIS; TIMBEROL; TRIMFIX O;

[0139] B3) At least one animalic / leather fragrance component, comprising about 0.01 wt% to about 1.5 wt%, more specifically about 0.01 wt% to about 1.41 wt%, of the fragrance components used in the fragrance composition, selected from: ANIMALIS 1745 SUBST. PMF2; juniper oil, essential oil, extract, substitute, or alternative, such as Spanish juniper oil; guaiacol; indole; indole, such as indole, indole 1% / TEC; indoleene liquid, such as indoleene liquid 50% / caster oil; suederal components, such as SUEDERAL LT 0710;

[0140] B4) At least one anise component, selected from: anethole; star anise oil; anisaldehyde; anisyl acetate; dihydroanenethole; tarragon; sweet cumin oil, essential oil, extract, flavor base, substitute or alternative, such as sweet cumin 50% DQ (AC) 24190TT; sweet cumin DQ (AC) N 41632TT; sweet cumin oil; sweet cumin oil TECH;

[0141] B5) At least one balsamic fragrance component comprising about 0.01 wt% to about 0.2 wt%, more specifically about 0.01 wt% to about 0.13 wt% of the fragrance components used in the fragrance composition, selected from: benzoin oil, essential oil, extract, substitute or alternative, such as benzoin SI GU ETA 50% BB AAF0515 41235EH; benzyl alcohol; benzyl cinnamate; frankincense oil, essential oil, extract, substitute or alternative, such as OLIBANUM COEUR DEP FREE 50% / TEC; Somali frankincense oil ORPUR; phenylethylphenyl acetate;

[0142] B6) At least one camphor-like / aromatic ingredient comprising about 0.01 wt% to about 10 wt%, more specifically about 0.01 wt% to about 8.13 wt% of the fragrance ingredients used in the fragrance composition, selected from: artemisia oil, essential oil, extract, substitute or alternative, such as Moroccan artemisia oil ORPUR COSMOS; camphor and camphor oil, essential oil, extract, substitute or alternative, such as camphor; white camphor oil; eucalyptol and eucalyptol oil, essential oil, extract, substitute or alternative, such as eucalyptol; Chinese eucalyptol oil COSMOS; hybrid lavender oil, essential oil, extract, substitute or alternative, such as LAVANDIN BRIALIS DQ(AC) XN 41665TT; French hybrid lavender oil ORPUR; hybrid lavender RGV 4; lavender oil, extract, essential oil, substitute or alternative, such as lavender DQ (AC) XN 41569TT; Rosemary oil, essential oil, extract, substitute or alternative, such as rosemary oil; reconstituted rosemary oil; Thuja oil, essential oil, extract, substitute or alternative, such as Korean Thuja oil;

[0143] B7) At least one floral fragrance component comprising about 30 wt% to about 80 wt%, more specifically about 32 wt% to about 79 wt% of the fragrance components used in the fragrance composition, selected from: acetal CD; pentyl cinnamaldehyde; amyl salicylate; pure nerolidin benzyl acetate; benzyl salicylate; borschtal; citronellol; citronellol acetate; p-cresol methyl ether; extra virgin aldehyde; cyclohexanal; cyclohexyl salicylate; methyl o-aminobenzoate; dimethylphenyl thyl carbinol; dobicarbamate; ethyl linalool; lily of the valley pyran; lily of the valley pyran HC; geraniol; geranium oil, essential oil, extract, substitute or substitute, such as geranium oil 230 / 3 MOD; geranium oil ABQ5629; bourbon geranium oil DQ (AC)XN 41563TT; Gynostemma pentaethyl acetate; Gynostemma pentaethyl butyrate; Methyl dihydrojasmonate; Methyl dihydrojasmonate HC; Salicylate foliol; Hexyl cinnamaldehyde; Hexyl cinnamaldehyde DQ AC XI 41505TT; Hexyl salicylate; Hydroxycitronellal; Isobutylphenyl acetate; Isobutyl salicylate; Hexylcyclopentanone; Jasmine oil, essential oil, extract, substitutes or alternatives, such as Jasmine absolute DQ (AC) 41568TT; JASMIN ARGENT 2; Cis-jasmone; Jasmine ester; Jasmine furan; Lily aldehyde and lily aldehyde substitutes; Linalool; Rose alcohol; Methyl anthranilate; Extra methyl anthranilate; Methyl benzoate; Methyl phenyl acetate; Neroli oil, essential oil, extract, substitutes or alternatives, such as Neroli essential oil base AB 7632; Neroli essential oil (NEROLI) PHASE ESS); NEROLINE crystals; NEROLIONE; orange oil, essential oil, extract, substitute or alternative, e.g., neroli TEC AB 2169E; sweet orange crystals; ORANGER FLEUR CREME 1103 / 20; tetrahydrogeraniol; paeonol; PETALIA; phenyl ethyl acetate; phenethyl alcohol; phenyl ethyl isovalerate; phenyl ethyl salicylate crystals; crystallized rose; 9-decenol; rose oil, essential oil, extract, substitute or alternative, e.g., rose base ABF0339A - K182572; rose TW 62 / 10 / 20; super mugwort; pure terpineol; tetrahydrolinalool; linden ester; ethylnaphthyl methyl ether; ylang-ylang oil, essential oil, extract, substitute or alternative, e.g., ylang-ylang AB 0388A; ylang-ylang ECO essential oil;

[0144] B8) At least one fruity aroma component comprising about 0.01 wt% to about 22 wt%, more specifically about 0.01 wt% to about 21.08 wt% of the aroma components used in the aroma composition, selected from: hexyl acetate; o-tert-butylcyclohexyl acetate; gluconate; allyl hexanoate; pineapple ester; allyl heptaate; amyl butyrate; avermanyl ester; apple oil, essential oil, extract, substitute or alternative, such as apple base ABF1016 - K108004; banana oil, essential oil, extract, substitute or alternative, such as banana base ABF0961A - K108784; benzyl butyrate; benzyl isobutyrate; benzyl propionate; butyl acetate; butyric acid; blackcurrant (Cassis) oil, essential oil, extract, substitute or alternative, such as blackcurrant base 345-F CS / 4 / 20; blackcurrant base 345B RECO TEC AB 8408D; Extra Grade Connaught White Oil DQ (AC) 41547TT; Cyclocarpine; Damascene; A-D ... 2927R; Diethyl malonate; Dimethyl benzyl acetate; Dimethyl benzyl butyrate; Dodecyl butyrate; Dodecyl butyrate; Ethyl acetoacetate; Ethyl butyrate; Ethyl hexanoate; Ethyl octanoate; Ethyl isopentyl ketone; Ethyl isobutyrate; Ethyl methyl-2-butyrate; Ethyl heptanoate; Ethyl nonanoate; Ethyl propionate; Ethyl crocinate; Tricyclodecenyl propionate; Strawberry ester; Apple ester; Fructose ester; Tricyclodecenyl isobutyrate; Chivadon; Guard oil, essential oil, extract, substitute or alternative, such as GUAVE DUPLICATION / 2; cis-3-hexenyl butyrate; cis-3-hexenyl isobutyrate; hexyl butyrate; hexyl isobutyrate; premium grade isoamyl acetate; isoamyl butyrate FR; tricyclodecenyl acetate; chamomile ester; melon oil, essential oil, extract, substitute or alternative, such as cantaloupe / 2; methoxyphenyl methyl ethyl ketone; pure methyl heptanone; methyl hexyl ketone; methyl-2-pentenoic acid; 2-fenazate; octyl lactone; peach aldehyde; phenoxyethyl isobutyrate; phenethyl isobutyrate; coconut aldehyde; raspberry aldehyde (N112); strawberry aldehyde;

[0145] B9) At least one fungal ingredient, selected from: pentylvinyl alcohol; ocimene, comprising about 0.001 wt% to about 0.01 wt%, more specifically about 0.001 wt% to about 0.002 wt% of the fragrance ingredients used in the fragrance composition;

[0146] B10) At least one gourmand ingredient, comprising about 0.01 wt% to about 1 wt%, more specifically about 0.01 wt% to about 0.86 wt%, of the flavoring ingredients used in the flavoring composition, selected from: acetyl methyl alcohol; acetyl pyrazine, such as acetyl pyrazine 1% / TEC; benzaldehyde; butyl butyryl lactate; chocolate oil, essential oil, extract, substitute or alternative, such as CHOCOLAT NOIR 1130 TEC / 3; CORYLONE DRIED; CYCLOTENE; ethyl maltol, such as ethyl maltol; ethyl maltol 1% / BA; high furanone, such as high furanone 20% / TEC; hydroxyethylmethylthiazole, such as hydroxyethylmethylthiazole 10% / TEC; vanillyl isobutyrate; maltol isobutyrate;

[0147] B11) At least one green fragrance component, comprising about 0.01 wt% to about 5 wt%, more specifically 0.041 wt% to about 4.28 wt% of the fragrance components used in the fragrance composition, selected from: acetal E; hexanol; food-grade hexanal; sec-butylquinoline; privet aldehyde; diphenyl ether; elintaal; ethyl decantereate (ETHYL) DECADIENOATE); Ethyl dimethyl pyrazine, e.g., pyrazine 1% / TEC; Grupone, e.g., Grupone 10%; Pure Grupone; Styrax acetate; trans-2-hexenal, e.g., trans-2-hexenal 10% / TEC; trans-2-hexenool; cis-3-hexenool; cis-3-hexeno acetate; cis-3-hexeno benzoate; cis-3-hexeno propionate; Isocyclocitral; Isohexylmethoxypyrazine, e.g., isohexylmethoxypyrazine 1% / TEC; Chlorpheniramine; Privet acetal; Marseillealdehyde; Octyryne carboxylate methyl ester; Neofull ester; Nonadienal, e.g., nonadienal; Nonadienal 1% / TEC C; 2,6-Nonadienol; cis-6-nonenal, e.g., cis-6-nonenal 10% / TEC; cis-6-nonenol; orange leaf oil, essential oil, extract, substitute or alternative, e.g., orange leaf ECO essential oil; Paraguayan orange leaf oil; phenoxyacetaldehyde, e.g., phenoxyacetaldehyde 50; phenylacetaldehyde, e.g., phenylacetaldehyde 50% / phenylethanol; pyralone; RESEDAL; rose ether; aromatic rose ether; olein; tricyclic terpenoid aldehyde; neoprivet aldehyde; undecanetriene; methyldecenol; iononitrile, e.g., iononitrile 0.1% / TEC; iononitrile 10% / TEC; phenylacetaldehyde dimethyl acetal;

[0148] B12) At least one herbal ingredient comprising about 0.01 wt% to about 0.5 wt%, more specifically 0.01 wt% to about 0.1 wt% of the fragrance ingredients used in the fragrance composition, selected from: basil oil, essential oil, extract, substitute or alternative, such as Egyptian basil oil ORPUR; chamomile oil, essential oil, extract, substitute or alternative, such as British chamomile DQ(AC) XN 41528TT; citronellal; clary sage oil, essential oil, extract, substitute or alternative, such as clary sage oil COSMOS; French clary sage oil ORPUR; CYPRISATE; eucalyptus oil, extract, essential oil, substitute or alternative, such as Brazilian lemon eucalyptus oil; lavender oxane; pinoacetal dehyde; tanaisone; thyme oil, essential oil, extract, substitute or alternative, such as thyme red oil 40-45%; thyme white oil DQ(AC). XN 41491TT; Thymol crystals;

[0149] B13) At least one marine / aquatic fragrance ingredient, comprising about 0.01 wt% to about 5 wt%, more specifically about 0.01 wt% to about 4.3 wt%, of the fragrance ingredients used in the fragrance composition, selected from: adolphin; azurone, such as AZURONE 10% / TEC; citrulline 1951; anisealdehyde; floralozone; anthocyanin; melon aldehyde; scentenal; jasmine aldehyde; senna aldehyde;

[0150] B14) At least one peppermint ingredient comprising about 0.01 wt% to about 0.5 wt%, more specifically about 0.01 wt% to about 0.47 wt% of the flavoring ingredients used in the flavoring composition, selected from: bromelain oil, essential oil, extract, substitute or alternative, such as South African bromelain oil COSMOS; L-carvone; Asian peppermint oil, essential oil, extract, substitute or alternative, such as Asian peppermint oil (CORNMINT OIL DEMENTHOLIZED); fresh peppermintone; isomenthone DL; L-menthol; menthol-DL; menthone; menthyl acetate; peppermint oil, essential oil, extract, substitute or alternative, such as PEPPERMINTAM FAR WEST DQ AC 41624TT; PEPPERMINT AM MID WEST MIW DQ AC 41253TT; PEPPERMINTAM WILL REDIST DQ AC 24150TT; PEPPERMINT AM WILLAM NAT DQ AC 37968TT; PEPPERMINT AMER 9303 DQ (AC) 37934TT; PEPPERMINT CHINESE T'LES (EXCN) DQ24329TT; PEPPERMINT CHINESE TR (CN) DQ 24109TT; PEPPERMINT CN TERPLESS FDC DQAC 37921TT; PEPPERMINT HMF DQ 24817TT; PEPPERMINT INDIAN TPC-1 DQ AC 24049TT; PEPPERMINT OIL BLEND; PEPPERMINT PIP IND REC.FDC DQ AC 24040TT; Spearmint oil, essential oil, extract, substitute or alternative, such as Spearmint AM FW NAT DQ AC XN 41610TT; Spearmint oil USA TYPE;

[0151] B15) At least one musk component, comprising about 0.01 wt% to about 50 wt%, more specifically about 0.01 wt% to about 44.43 wt% of the fragrance components used in the fragrance composition, selected from: asterolone; cashmere; musk; cyclopentadecanolone, such as cyclopentadecanolone DQ 1% PG; musk T; galacmus; galacmus S; cyclopentadecanolone; musk ketone; protomus C14; white musk (SERENOLIDE); cyclohexadecylolone; sylkolide; cyclohexadecylone;

[0152] B16) At least one iris component, comprising about 0.01 wt% to about 10 wt% of the fragrance components used in the fragrance composition, selected from: allyl ionone; dihydro-ethyl ionone; ethyl ionone; methyl ionone; pure ionone; isomethyl ionone 70; isomethyl ionone 95; irisone;

[0153] B17) At least one spice component comprising about 0.01 wt% to about 1 wt%, more specifically about 0.01 wt% to about 0.45 wt% of the spice components used in the spice composition, selected from: cardamom oil, essential oil, extract, substitute or alternative, such as cardamom seed oil ORPUR; cardamom substitute 1527 F; cardamom substitute 1527 F / 2; caryophyllene; cinnamyl alcohol; cinnamyl alcohol; cinnamaldehyde; cinnamon leaf oil, essential oil, extract, substitute or alternative, such as washed cinnamon leaf oil ORPUR; clove oil, essential oil, extract, substitute or alternative, such as clove bud oil; colorless clove leaf oil; refined clove leaf oil RB COSMOS; coriander oil, essential oil, extract, substitute or alternative, such as coriander seed oil ORPUR. COSMOS; elemenine oil, essential oil, extract, substitute or alternative, e.g., elemenine resin 50% / BB; ethyl cinnamate; eugenol; ginger oil, essential oil, extract, substitute or alternative, e.g., Indian ginger oil ORPUR; fresh ginger root slices; isoeugenol; methyl cinnamate; methyl isoeugenol; MYSTIKAL; nutmeg oil, essential oil, extract, substitute or alternative, e.g., Indonesian nutmeg oil; pepper oil, essential oil, extract, substitute or alternative, e.g., Madagascar black pepper oil ORPUR; Sichuan pepper (ASH BARK) DQ AF 24070TT;

[0154] B18) At least one sulfur-containing component, comprising about 0.01 wt% to about 0.5 wt%, more specifically about 0.01 wt% to about 0.21 wt% of the fragrance ingredients used in the fragrance composition, selected from: Anjeruk, e.g., ANJERUK 0.01% / TEC; Corps cassis, e.g., CORPS CASSIS 0.1% / TEC; CORPS CASSIS 10% / TEC; Corps pamplemousse, e.g., CORPS PAMPLEMOUSSE PURE 1% / TEC; CORPS PAMPLEMOUSSEPURE 10% / TEC; dimethyl sulfide, e.g., dimethyl sulfide; dimethyl sulfide 1% / TEC; cyclic amine (GARDAMIDE); rapin, e.g., rapin 1% / IPM-TEC; thiol compounds, e.g., mercapto-8-menthene-1 PARA 0.1% IN TEC; Methylisopropylthiazole; Nardozeste oil, essential oil, extract, substitute or alternative, such as NARDOZESTE ABQ5031; NEOCASPIRENE EXTRA; Nolanylamine 1% triacetin; Oxane, such as Oxane 50% / TEC; Fruit amide; Paramenthone, such as Paramenthone 1% / TEC;

[0155] B19) At least one sweet / powdery fragrance component, comprising about 0.01 wt% to about 10 wt%, more specifically about 0.2 wt% to about 7.83 wt%, of the fragrance components used in the fragrance composition, selected from: acetophenone; aubepine paracresol; dicyclononalactone; coumarin; ethyl lactone, such as ethyl lactone 1% / TEC; ethyl vanillin; jasmine aldehyde vanilla oil, essential oil, extract, substitute or alternative, such as vanilla absolute 20 FOLD DQ AC41493TT; vanilla S / ABS DEC 50% PG AAF0517 L228655; vanilla SUP ABS DEC DQ P17 SBAC 41561TT; vanilla DQ (AF) 41319TT; vanillin; vanillin DQ (AF) 41320TT; Vanolia Oil, essential oil, extract, substitute or alternative, such as VANOLIA fragrance base ABF0303B; veratraldehyde (VERATRIC ALDEHYDE);

[0156] B20) comprises, in about 0.01 wt% to about 15 wt%, more specifically about 0.01 wt% to about 10.37 wt%, of at least one woody / rosin component selected from: borneol; borneol acetate liquid; p-butylcyclohexanol; p-butylcyclohexyl acetate; cedarwood oil, essential oil, extract, substitute or alternative, such as Virginia cedarwood oil ORPUR; fennelol; ebony alcohol; synthetic oakmoss; fennel acetate; guaiac oil, essential oil, extract, substitute or alternative, such as Paraguayan guaiac oil; isononyl acetate; Java sandalwood; gentamicin; dihydrorosinyl acetate (MENTHANYL) ACETATE; methyl cedryl ketone; nobutyl acetate; spironolactone; oxyoctalineformate; patchouli oil, essential oil, extract, substitute or alternative, such as Indonesian colorless patchouli oil; Indonesian iron-free patchouli oil (COSMOS); methyl-pinene; ethyl-pinene; santalol; super santalol; turpentine oil, essential oil, extract, substitute or alternative, such as refined turpentine oil; superior grade methyl cedryl ketone; vetiver oil, essential oil, extract, substitute or alternative, such as Haitian vetiver oil (ORPUR ORGANIC COSMOS);

[0157] and optional

[0158] B21) At least one component comprising about 0.01 wt% to about 10 wt% of the fragrance ingredients used in the fragrance composition, selected from: C12 aldehyde (dodecanoic acid; menthyl acetate);

[0159] 4. A consumer product comprising the flavoring composition described in any one of items 1-3.

[0160] 5. The consumer products mentioned in item 4 are selected from laundry care products, personal care products, oral care products, air care products, or household care products.

[0161] 6. The air freshener product of item 5, comprising the fragrance composition as defined in item 1 or 2, comprising 0.01% to 25% by weight of the fragrance composition.

[0162] 7. The oral care product of claim 5, comprising the fragrance composition as defined in claim 1 or 2, comprising 0.01% to 60% by weight of the fragrance composition.

[0163] 8. The fabric care product of item 5, comprising the fragrance composition as defined in item 1 or 2, comprising 0.01% to 20% by weight of the fragrance composition.

[0164] 9. The personal care product of claim 5, comprising the fragrance composition as defined in claim 1 or 2, comprising 0.01% to 20% by weight of the fragrance composition.

[0165] 10. The home care product of item 5, comprising the fragrance composition as defined in item 1 or 2, comprising 0.01% to 34% by weight of the fragrance composition.

[0166] 11. A method for preparing a fragrance composition, the method comprising the step of combining functional fragrance ingredients in a manner such that the combination has a Sandman classification value greater than 1.35.

[0167] 12. A method for improving sleep quality by inhaling an effective amount of a fragrance composition as defined in items 1-3.

Claims

1. A consumer product comprising a flavoring composition, said flavoring composition comprising at least two, more specifically at least five, still more specifically ten or more flavoring ingredients having a known Sandman classification (SC) value of at least 1.35, wherein said Sandman classification value is determined by: - Brainwave activity in human subjects after inhalation of the flavoring composition was measured using electroencephalography (EEG) with a standard 10-20 electrode system; and - The Sandman Classification (SC) value is determined using the following formula: SC = ((а1 ce + Θ ce ) / δ tem ) + (Θ / а2) in: a1 ce This represents the amplitude value of α-1 brainwave activity with an oscillation frequency of 8-12 Hz at the central electrodes C3, C4, and Cz. Θ ce The amplitude values ​​of theta brainwave activity with an oscillation frequency of 4-7 Hz at the central electrodes C3, C4, and Cz are represented. δ tem The amplitude values ​​of theta brainwave activity with oscillation frequencies of 0.1–3 Hz at instantaneous electrodes T7 and T8; and Θ / а2 represents the ratio of the amplitude of theta brainwave activity with an oscillation frequency of 4-7 Hz through all electrodes to the amplitude of α-2 brainwave activity with an oscillation frequency of 12-15 Hz.

2. The consumer product according to claim 1, wherein the fragrance component with a known SC value accounts for 0.1 wt% to 100 wt% of the fragrance composition, more specifically 8.5 wt% to 100 wt%, and still more specifically 34 wt% to 71 wt%.

3. The consumer product according to claim 1 or 2, wherein the fragrance composition comprises at least 0.01% by weight of a fragrance material selected from the group consisting of: A) At least one citrus ingredient comprising 1 wt% to 30 wt% of the total flavor components used in the flavor composition, selected from: bergamot oil, essential oil, extract, fragrance base, substitute or alternative; citronellal; citral; citronellol; citronellal; p-cymene; dihydromyrcenol; dimethyloctenone; 2,6-dimethylheptanol; florfenicol; grapefruit oil, essential oil, extract, substitute or alternative; lemon oil, essential oil, extract, fragrance base, substitute or alternative; citronellal; linalool oxide; synthetic linalyl acetate; Litsea cubeba oil, essential oil; Extracts, substitutes, or alternatives; orange oil, essential oil, extract, fragrance base, substitutes, or alternatives; turmeric methane; myrcene 90; orange oil, essential oil, extract, fragrance base, substitutes, or alternatives; orange leaf oil, essential oil, extract, fragrance base, substitutes, or alternatives; cyclohexane B; isopentenyl acetate; cyclic ethers (RHUBAFURAN); tamarind oil, essential oil, extract, fragrance base, substitutes, or alternatives; mandarin orange oil, essential oil, extract, essential oil, fragrance base, substitutes, or alternatives; propylterpinene; isoprene; and terpineyl acetate; And at least one of at least five ingredients from groups B1-B20, in the amounts shown: B1) At least one aldehyde component comprising 0.01 wt% to 1.5 wt% of the fragrance components used in the fragrance composition, selected from: decanal; undecenal; undecenal; lauraldehyde; methyl nonanal; edible grade octanal; isononanal; edible grade nonanal; nonenal 1% / TEC; C12 aldehyde (dodecanal); isoundecenal; saffron aldehydes; trans-4-decenal; dihydrofarnesal; dodecanal; myraldene; and saffron ester; B2) At least one amber component comprising 0.01 wt% to 25 wt% of the fragrance components used in the fragrance composition, selected from: ambergris acetal; Ambermax; Ambrocenide; Ambrofuran; Ambrofuran tablets; Belambre; Ethoxymethoxycyclododecane; cypress acetate liquid; cypress methyl ether; super ambergris ether; ambergris ketone; carrageenan; KEPHALIS; TIMBEROL; TRIMFIX O; B3) At least one animalic / leather fragrance component, comprising 0.01wt% to 1.5wt% of the fragrance components used in the fragrance composition, selected from: ANIMALIS 1745 SUBST. PMF 2; juniper oil, essential oil, extract, substitute, alternative; guaiacol; indole; indole; indole solution; suederal components; B4) At least one anise component comprising 0.01wt%-0.2wt% of the flavoring components used in the flavoring composition, selected from: anethole; star anise oil; anisaldehyde; anisyl acetate; dihydroanenethole; tarragon; sweet cumin oil, essential oil, extract, flavor base, substitute or alternative; B5) At least one balsamic fragrance component comprising 0.01wt% to 0.2wt% of the fragrance components used in the fragrance composition, selected from: benzoin oil, essential oil, extract, substitute or alternative; benzyl alcohol; benzyl cinnamate; frankincense oil, essential oil, extract, substitute or alternative; phenylethylphenyl acetate; B6) At least one camphor-like / aromatic ingredient, comprising 0.01 wt% to 10 wt% of the fragrance ingredients used in the fragrance composition, selected from: artemisia oil, essential oil, extract, substitute or alternative; camphor and camphor oil, essential oil, extract, substitute or alternative; eucalyptol and eucalyptol oil, essential oil, extract, substitute or alternative; mixed lavender oil, essential oil, extract, substitute or alternative; lavender oil, extract, essential oil, substitute or alternative; rosemary oil, essential oil, extract, substitute or alternative; arborvitae oil, essential oil, extract, substitute or alternative; B7) At least one floral fragrance component comprising 30 wt% to 80 wt% of the fragrance components used in the fragrance composition, selected from: acetal (CD); pentyl cinnamaldehyde; amyl salicylate; pure nerolidin benzyl acetate; benzyl salicylate; berberine; citronellol; citronellol acetate; p-cresol methyl ether; extra fenestration aldehyde; cyclohexanal; cyclohexyl salicylate; methyl o-aminobenzoate; dimethyl phenyl thyl carbinol; dobicarbamate; ethyl linalool; lily of the valley pyran; lily of the valley pyran HC; geraniol; geranium oil, essential oil, extract, substitute or substituted product; geraniol; geraniol acetate; geraniol butyrate; methyl dihydrojasmonate; methyl dihydrojasmonate HC; geraniol salicylate; hexyl cinnamaldehyde; hexyl cinnamaldehyde DQ AC XI 41505TT; Hexyl salicylate; Hydroxycitronellal; Isobutylphenyl acetate; Isobutyl salicylate; Hexylcyclopentanone; Jasmine oil, essential oil, extract, substitutes or alternatives; cis-jasmineone; Jasmine ester; Jasmine furan; Lily of the valley aldehyde and its substitutes; Linalool; Rose alcohol; Methyl anthranilate; Extra grade methyl anthranilate; Methyl benzoate; Methyl phenyl acetate; Neroli oil, essential oil, extract, substitutes or alternatives; NEROLINE crystals; NEROLIONE; Sweet orange crystals; ORANGER FLEUR CREME 1103 / 20; Tetrahydrogeraniol; Paeonol; PETALIA; Phenylethyl acetate; Phenylethanol; Phenylethyl isovalerate; Phenylethyl salicylate crystals; Crystallized rose; 9-Decenol; Rose oil, essential oil, extract, substitutes or alternatives; Super Lily of the Valley (SUPER) MUGUET); pure terpineol; tetrahydrolinalool; linden ester; ethylnaphthalene methyl ether; ylang-ylang oil, essential oil, extract, substitute or alternative; B8) At least one fruity flavoring component, comprising 0.01 wt% to 22 wt% of the flavoring components used in the flavoring composition, selected from: hexyl acetate; o-tert-butylcyclohexyl acetate; gluconate; allyl hexanoate; pineapple ester; allyl heptaate; amyl butyrate; avermanyl acetate; apple oil, essential oil, extract, substitute or alternative; banana oil, essential oil, extract, substitute or alternative; benzyl butyrate; benzyl isobutyrate; benzyl propionate; butyl acetate; butyric acid; blackcurrant (Cassis) oil, essential oil, extract, substitute or alternative; Connaught White Oil DQ (AC) 41547TT; Cyclogalamyl; Damascene; A-damascene; B-damascene; C-damascene; D-decanolide; C-decanolide; Dewfruit oil, essential oil, extract, substitute or alternative; Diethyl malonate; Dimethyl benzyl acetate; Dimethyl benzyl butyrate; D-dodecanolide; C-dodecanolide; Ethyl acetoacetate; Ethyl butyrate; Ethyl hexanoate; Ethyl octanoate; Ethyl isopentyl ketone; Ethyl isobutyrate; Ethyl methyl-2-butyrate; Ethyl heptanoate; Ethyl nonanoate; Ethyl propionate; Ethyl crocinate; Tricyclodecenyl propionate; Strawberry ester; Apple ester; Fructose Esters (FRUITATE); Tricyclodecenyl isobutyrate; Chihuatan ketone; Guard oil, essential oil, extract, substitute or alternative; cis-3-hexenyl butyrate; cis-3-hexenyl isobutyrate; Hexyl butyrate; Hexyl isobutyrate; Extra grade isoamyl acetate; Isoamyl butyrate FR; Tricyclodecenyl acetate; Matricariacetin; Melon oil, essential oil, extract, substitute or alternative; Methoxyphenyl methyl ethyl ketone; Pure methyl heptanone; Methyl hexyl ketone; Methyl-2-pentenoic acid; 2-Zinc ketone; Octyl lactone; Prunal; Phenoxyethyl isobutyrate; Phenylethyl isobutyrate; Cocoaldehyde; Raspberry ketone (N112); Strawberry aldehyde; B9) At least one fungal ingredient, comprising 0.001 wt% to 0.01 wt% of the fragrance ingredients used in the fragrance composition, selected from: pentylvinyl alcohol; ocimene; B10) At least one gourmand ingredient comprising 0.01 wt% to 1 wt% of the flavoring ingredients used in the flavoring composition, selected from: acetyl methyl alcohol; acetyl pyrazine; butyl butyryl lactate; chocolate oil, essential oil, extract, substitute or alternative; CORYLONE DRIED; CYCLOTENE; ethyl maltol; high furanone; hydroxyethyl methylthiazole; vanillyl isobutyrate; maltol isobutyrate; B11) At least one green aromatic component, comprising 0.01 wt% to 5 wt% of the aromatic components used in the flavoring composition, selected from: acetal E; hexanol; food-grade hexanal; sec-butylquinoline; privet aldehyde; diphenyl ether; elintaal; ethyl sebacate. DECADIENOATE); Ethyl dimethylpyrazine; Grupone; Styrax acetate; trans-2-hexenal; trans-2-hexenol; cis-3-hexenol; cis-3-hexenyl acetate; cis-3-hexenyl benzoate; cis-3-hexenyl propionate; Citral; Isohexylmethoxypyrazine; Chlorophyll; Privet acetal; Marseilles aldehyde; Octyryne carboxylic acid methyl ester; Neofull ester; Nonadienal; 2,6-Nonadienol; cis-6-Nonenal; cis-6-Nonenol; Phenoxyacetaldehyde; Phenylacetaldehyde; Pyralone; RESEDAL; Rose ether; Aromatic rose ether; Olive ketone; Tricyclic terpenoid aldehyde; Neoprivet aldehyde; Undecanetriene; Methyldecenol; Iononitrile; Phenylacetaldehyde dimethyl acetal; B12) At least one herbal fragrance component, comprising 0.01 wt% to 0.5 wt% of the fragrance components used in the fragrance composition, selected from: basil oil, essential oil, extract, substitute or alternative; chamomile oil, essential oil, extract, substitute or alternative; citronellal; clary sage oil, essential oil, extract, substitute or alternative; CYPRISATE; eucalyptus oil, extract, essential oil, substitute or alternative; lavender oxane; pinoacetal dehyde; tanaisone; thyme oil, essential oil, extract, substitute or alternative; thymol crystals; B13) At least one marine / aquatic fragrance component, comprising 0.01 wt% to 5 wt% of the fragrance components used in the fragrance composition, selected from: adolphin; azurone; citrulline 1951; anisealdehyde; floralozone; anthocyanin; melon aldehyde; scentenal; jasmine aldehyde; senna aldehyde; B14) At least one peppermint ingredient, comprising 0.01 wt% to 0.5 wt% of the flavoring ingredients used in the flavoring composition, selected from: buchu leaf oil, essential oil, extract, substitute or alternative; L-carvone; Asian peppermint oil, essential oil, extract, substitute or alternative; fresh menthone; isomenthone DL; L-menthol; menthol-DL; menthone; menthyl acetate; peppermint oil, essential oil, extract, substitute or alternative; spearmint oil, essential oil, extract, substitute or alternative; B15) At least one musk component comprising 0.01 wt% to 50 wt% of the fragrance components used in the fragrance composition, selected from: asterolide; cashmere; musk; cyclopentadecanolide; musk T; galacmus; galacmus S; cyclopentadecanolide; musk ketone; proto-musk C14; white musk (SERENOLIDE); cyclohexadecylolide; sylkolide; cyclohexadecylone; B16) At least one iris component comprising 0.01 wt% to 10 wt% of the fragrance components used in the fragrance composition, selected from: allyl ionone; dihydro-ethyl ionone; ethyl ionone; methyl ionone; pure ionone; isomethyl ionone 70; isomethyl ionone 95; irisone; B17) At least one spice component comprising 0.01 wt% to 1 wt% of the spice components used in the spice composition, selected from: cardamom oil, essential oil, extract, substitute or alternative; caryophyllene; cinnamyl alcohol; cinnamaldehyde; cinnamon leaf oil, essential oil, extract, substitute or alternative; clove oil, essential oil, extract, substitute or alternative; coriander oil, essential oil, extract, substitute or alternative; elemi oil, essential oil, extract, substitute or alternative; ethyl cinnamate; eugenol; ginger oil, essential oil, extract, substitute or alternative; isoeugenol; methyl cinnamate; methyl isoeugenol; MYSTIKAL; nutmeg oil, essential oil, extract, substitute or alternative; pepper oil, essential oil, extract, substitute or alternative; Sichuan pepper (ASH BARK) DQ AF24070TT; B18) At least one sulfur-containing component, comprising 0.01 wt% to 0.5 wt% of the flavoring ingredients used in the flavoring composition, selected from: Anjeruk; Corps cassis; Corps pamplemousse; dimethyl sulfide; cyclic amine (GARDAMIDE); rapinol; thiol compounds; methyl isopropylthiazole; Nardozeste oil, essential oil, extract, substitute or alternative; NEOCASPIRENE EXTRA; novaline 1% triacetin; oxane; fruit amide; paramenthone; B19) At least one sweet / powdery fragrance component, comprising 0.01 wt% to 10 wt% of the fragrance components used in the fragrance composition, selected from: acetophenone; aubepine paracresol; dicyclononolactone; coumarin; ethyl lactone; ethyl vanillin; jasmine aldehyde; vanilla oil, essential oil, extract, substitute or alternative; vanilla oil, essential oil, extract, substitute or alternative; veratraldehyde; B20) At least one woody / rosin component, comprising 0.01 wt% to 15 wt% of the fragrance components used in the fragrance composition, selected from: borneol; borneol acetate liquid; p-butylcyclohexanol; p-butylcyclohexyl acetate; cedarwood oil, essential oil, extract, substitute or alternative; senna; ebony alcohol; synthetic oakmoss; fennel acetate; guaiac oil, essential oil, extract, substitute or alternative; isononyl acetate; Java sandalwood; senna alcohol; menthamyl acetate; methyl pine resin ketone; nobute acetate; spironolactone; oxyoctamethrin. FORMATE); Patchouli oil, essential oil, extract, substitute or alternative; methyl-pinene; ethyl-pinene; santalol; super santalol; turpentine oil, essential oil, extract, substitute or alternative; superior grade methyl cedar ketone; vetiver oil, essential oil, extract, substitute or alternative; and optional B21) At least one component comprising 0.01 wt% to 10 wt% of the flavoring components used in the flavoring composition, selected from: C12 aldehyde; and menthyl acetate.

4. The consumer product according to any one of the preceding claims, wherein the fragrance composition comprises at least one ingredient from group B7 in the indicated amount.

5. The consumer product according to any one of the preceding claims, wherein the fragrance composition comprises at least one ingredient in the indicated amount from at least four of the groups B1-B4, B6, B8, B10, B11 and B13-B20.

6. The consumer product according to any one of the preceding claims, wherein the fragrance composition comprises at least one ingredient from each of the groups B1, B11, B18 and B19 in the indicated amounts.

7. The consumer product according to any one of the preceding claims, wherein the fragrance composition comprises B1) 0.042% of at least one aldehyde component, A) 10.938% of at least one citrus component, B11) 4.271% of at least one green component, B13) 3.396% of at least one marine / aquatic component, B18) 0.208% of at least one sulfur-containing component, B7) 63.542% of at least one floral component, B16) 2.083% of at least one iris component, B8) 12.604% of at least one fruity component, B2) 2.083% of at least one amber component, B3) 0.042% of at least one animalic / leathery component, B19) 0.271% of at least one sweet / powdery component, and B20) 0.521% of at least one woody / pine component.

8. The consumer product according to any one of claims 1-7, wherein the fragrance composition comprises B1) 0.221% of at least one aldehyde component, A) 1.905% of at least one citrus component, B11) 3.087% of at least one green component, B13) 2.346% of at least one marine / aquatic component, B18) 0.060% of at least one sulfur-containing component, B7) 59.944% of at least one floral component, B16) 10.024% of at least one iris component, B8) 21.071% of at least one fruity component, B17) 0.441% of at least one spicy component, B10) 0.200% of at least one gourmet component, B19) 0.200% of at least one sweet / powdery component, and B20) 0.501% of at least one woody / pine component.

9. The consumer product according to any one of the preceding claims, wherein the product is selected from laundry care products, personal care products, oral care products, air care products, and home care products.

10. The consumer product according to claim 9, wherein the product is selected from: - Air freshener products containing 0.01%-25% by weight of a fragrance composition; - Oral care products containing 0.01% to 60% by weight of a fragrance composition; - Fabric care products containing 0.01%-20% by weight of a fragrance composition; - Personal care products containing 0.01%-20% by weight of a fragrance composition; and - Home care products containing 0.01%-34% by weight of a fragrance composition.

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