Touchless transfer capping system for multi-specification packaging material filling

Abstract

This application relates to a contactless transfer and capping system for filling multi-specification packaging materials, including a turntable device that performs rotary feeding motion, multiple circumferentially distributed support seats, and a process module group containing filling, capping, and functional modules. The turntable device has a process execution station; when the bottle tray enters this station, it is mechanically decoupled from the turntable device to be in an independent state, allowing the corresponding module to perform independent process actions. After the action is completed, it is recoupled and reset. This system is configured with a first configuration state for handling unidirectional flow packaging materials and a second configuration state for handling dual-lumen syringes. The orientation of the packaging materials and forward / reverse processing are achieved by calling a flipping module. This application achieves compatible production of multi-specification single and dual-lumen packaging materials on the same turntable base, eliminating vibration and friction interference during high-precision weighing and inspection. Furthermore, the avoidance structure of the transfer mechanism allows laminar airflow penetration, meeting high-level aseptic production standards.

Description

Technical Field

[0001] This application relates to the field of biopharmaceutical technology, and in particular to a contactless transfer stoppering system for filling multi-specification packaging materials. Background Technology

[0002] In modern biopharmaceutical and sterile preparation production, filling and capping systems are core production equipment. With the development of pharmaceutical packaging technology, the types of packaging materials on the market are becoming increasingly diversified, mainly including single-cavity packaging materials such as pre-filled syringes, cartridges, and vials, as well as pre-filled double-cavity syringes with more complex processes.

[0003] Currently, existing filling and capping equipment typically suffers from the following technical defects: First, existing rotary filling machines are often custom-designed for specific packaging materials. Single-chamber packaging materials typically use a unidirectional continuous flow process; however, dual-chamber syringes, with two independent chambers (such as a lyophilized powder chamber and a solvent chamber), require filling and capping at both ends, necessitating in-situ inversion or even reverse flow capabilities. Existing equipment struggles to simultaneously accommodate these two drastically different process paths on a single rotary base, forcing pharmaceutical companies to purchase multiple custom-designed machines. This not only incurs high procurement costs but also significantly occupies space in high-level cleanrooms.

[0004] Secondly, in existing turntable systems, packaging materials or their pallets often remain in physical contact with the turntable base or guide rails during high-precision online weighing or 360-degree visual inspection. This mechanical coupling introduces equipment vibration and frictional resistance, leading to distortion of minute weighing (milligram-level) data. Simultaneously, physical friction easily scratches the outer walls of packaging materials made of polymers such as COP / COC, causing the product to be mistakenly identified as defective during subsequent pharmaceutical light inspection. Summary of the Invention

[0005] To address the aforementioned issues, this application provides a contactless transfer and inserting system that enables high-precision, lossless, and compatible production of multi-specification single and double-cavity packaging materials on the same equipment platform.

[0006] To achieve the above objectives, this application presents a contactless transfer and capping system for filling multi-specification packaging materials, comprising: The rotary table device is driven by a drive mechanism to perform rotary feed motion; Multiple bottle holders are distributed circumferentially along the turntable device, and each bottle holder has a positioning structure for carrying packaging materials; A process module group is arranged around the circumference of the turntable device, and the process module group includes at least a filling module, a stoppering module and at least one functional module; The turntable device is provided with at least one process execution station, and the bottle holder is mechanically decoupled from the turntable device to be in an independent state when it enters the process execution station. In the independent state, the corresponding module in the process module group can perform independent process actions for the bottle tray or the packaging material it carries; after the action is completed, the bottle tray is recoupled and reset to the turntable device.

[0007] Preferably, the system has a first configuration state for processing a first type of packaging material: In the first configuration state, the process execution station includes a weighing station, and the process module group further includes a weighing module; At the weighing station, the bottle tray in the independent state, together with the packaging material it carries, maintains a non-contact gap with the turntable device so that the weighing module can perform the weighing operation. The first type of packaging material maintains its initial rotation direction and flows unidirectionally on the turntable device, and sequentially completes the corresponding process steps through the corresponding process execution station.

[0008] Preferably, the system has a second configuration state for processing the second type of packaging materials: In the second configuration state, the process execution station includes a first flip station, and the functional module includes a first flip module located at the station; At the first flipping station, the first flipping module extracts the packaging material from the bottle tray in the independent state and performs a flipping and reversing action, and then puts it back into the bottle tray to switch the opening orientation of the packaging material.

[0009] Preferably, the process module group further includes a second flipping module located downstream of the first flipping module, and a capping module located upstream of the first flipping station; In the second configuration state, the processing operation of the second type of packaging material includes a first processing stage and a second processing stage: In the first processing stage, the drive mechanism drives the turntable device to perform a reverse rotation action opposite to the initial rotation direction. The packaging material moves in the opposite direction with the turntable device, and the first plugging and first filling process of the first end are completed in sequence while maintaining the initial orientation. In the second processing stage, the drive mechanism drives the turntable device to restore the initial rotation direction in a forward motion. The packaging material that has undergone the first processing stage moves forward with the turntable device. After the capping module performs the capping operation, the first flipping module extracts the packaging material and performs a flipping and reversing operation. After being flipped, the packaging material continues to move forward with the turntable device to reuse the filling module and the stoppering module in the process module group to perform a second filling and a second stoppering operation; then the second flipping module extracts and performs a flipping and reversing action to reset it to the initial orientation; The system is configured to support the packaging material to be continuously rotated online on the turntable device between the first processing stage and the second processing stage, or to be reloaded onto the turntable device for rotation after offline unloading.

[0010] Preferably, the process execution station further includes a vision inspection station, and the functional module includes a rotary drive mechanism located at the station; at the vision inspection station, the rotary drive mechanism is mechanically coupled to the bottle holder in an independent state, and drives the bottle holder and the packaging material it carries to rotate circumferentially, so that the laterally arranged vision sensor can acquire image data of the circumferential surface of the packaging material.

[0011] Preferably, the turntable device includes a rotating drive disc and a fixed support disc arranged at intervals; the rotating drive disc has a plurality of circumferentially distributed positioning grooves, the bottle holder is placed in the positioning grooves and a clearance gap is provided between its side wall and the inner wall of the positioning groove; the surface of the fixed support disc has a circumferentially extending raised slide rail, and the bottom surface of the bottle holder has a bottom groove into which the raised slide rail extends, and there is a non-contact gap between the raised slide rail and the inner wall of the bottom groove; in non-process execution positions, the rotating drive disc rotates so that the side wall of the positioning groove abuts against the outer side wall of the bottle holder to form a transmission and limiting engagement, thereby driving the bottle holder to move circumferentially with the rotating drive disc.

[0012] Preferably, the fixed support plate at the process execution station is provided with a guide rail notch, and a process execution support component is provided in the guide rail notch, which is independently configured from the fixed support plate; when the bottle holder moves to the guide rail notch, the bottle holder disengages from the raised slide rail and is supported by the process execution support component, and at this time the bottle holder is in a radial and circumferential suspended state in the positioning groove, so as to achieve the mechanical decoupling.

[0013] Preferably, the process execution station further includes a vision inspection station; the process execution support at the vision inspection station is a rotating support; the top support surface of the rotating support is provided with a limiting rib, and the rotating support is configured such that: in the independent state, the top support surface supports the bottom surface of the bottle holder upwards, thereby driving the bottle holder to perform circumferential rotation; at the same time, the limiting rib extends into the bottom groove of the bottom surface of the bottle holder and there is a gap between the two, so as to limit the bottle holder during the rotation process and prevent the bottle holder from having a positional deviation; so that the laterally arranged vision sensor can acquire image data of the circumferential surface of the packaging material.

[0014] Preferably, it further includes a linkage feeding mechanism, which includes a rotatable nesting board support platform and a rotatable feeding mechanical clamp. The rotation axis of the nesting board support platform is parallel to the rotation axis of the feeding mechanical clamp. The feeding mechanical clamp is configured to extract packaging materials at different coordinate positions inside the nesting board and transfer them to the bottle holder by rotating in a phase-coupled motion with the nesting board support platform.

[0015] Preferably, the feeding mechanism includes a support cantilever and a gripper located at the end of the support cantilever. The support cantilever and / or the gripper have a vertically penetrating clearance structure on their bodies. The clearance structure is configured to allow laminar airflow from top to bottom to vertically penetrate and blow toward the opening end of the packaging material.

[0016] The contactless transfer and capping system designed in this application for filling multi-specification packaging materials achieves this by setting up a mechanically decoupled process execution station on the turntable device. This allows the bottle tray to operate independently, eliminating interference from equipment vibration and physical friction, ensuring weighing and detection accuracy, and preventing damage to the packaging materials. The system, through the configuration of switchable configuration states and function flip modules, enables compatible production of single-cavity packaging materials with unidirectional flow and dual-cavity syringes requiring bidirectional processing on the same turntable base, improving equipment versatility and saving workshop space. Furthermore, the transfer mechanism with a clearance structure allows direct penetration of vertical laminar airflow, eliminating dead airflow angles above open packaging materials, reducing the risk of microbial contamination, and meeting the aseptic production standards of high-level clean areas. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the non-contact transfer and insertion system provided in the embodiments of this application.

[0018] Figure 2 This is a schematic diagram of the arrangement of the process module group provided in the embodiments of this application.

[0019] Figure 3 This is a schematic diagram of the structure of the turntable device provided in the embodiments of this application.

[0020] Figure 4 This is a schematic diagram of the structure of a contactless transfer and insertion system provided in another embodiment of this application.

[0021] Figure 5 yes Figure 4 Enlarged diagram of point A in the middle.

[0022] Figure 6 This is a schematic diagram of the arrangement of process module groups provided in another embodiment of this application.

[0023] Figure 7 This is a schematic diagram of the positional arrangement of the vision sensor provided in the embodiments of this application.

[0024] Figure 8 yes Figure 7 A three-dimensional exploded view.

[0025] Figure 9 This is a schematic diagram of the workflow of the contactless transfer and insertion system provided in the embodiments of this application.

[0026] The components include: a turntable device 10, a drive mechanism 11, a rotary drive disk 12, a positioning groove 121, a fixed support disk 13, a raised slide rail 131, a guide rail notch 132, a bottle holder 20, a positioning structure 21, a bottom groove 22, a first type of packaging material 31, a second type of packaging material 32, a process module group 40, a filling module 41, a stopper module 42, a weighing module 44, a first flipping module 45, a second flipping module 46, a capping module 47, a rotary drive mechanism 48, a process execution station 50, a weighing station 51, a first flipping station 52, a vision inspection station 53, a vision sensor 60, a process execution support component 70, a rotary support 71, a limiting rib 711, a linkage feeding mechanism 80, a nest board support platform 81, a feeding mechanical clamp 82, a support cantilever 821, a gripper 822, a clearance structure 823, and a nest board 90. Detailed Implementation

[0027] The preferred embodiments of this application are described below with reference to the accompanying drawings. It should be understood that the preferred embodiments described herein are for illustration and explanation only and are not intended to limit this application.

[0028] like Figures 1 to 9 As shown in the figure, this embodiment provides a contactless transfer and stoppering system for filling multi-specification packaging materials. Its overall architecture and the specific mechanical structure and motion logic of each functional module are described below.

[0029] Specifically, the main structure of the contactless transfer and capping system provided in this embodiment includes a turntable device 10 and a plurality of bottle holders 20 equidistantly distributed along the circumference of the turntable device 10. The turntable device 10 is driven by a drive mechanism 11 configured as a servo motor or indexing cam to perform a rotary feed motion with the desired accuracy. Each bottle holder 20 has a positioning structure 21 for independently carrying the packaging material. The inner surface of the positioning structure 21 is conformally adapted to the outer contour of the packaging material to ensure the posture stability of the packaging material during the transfer process. A process module group 40 is arranged circumferentially around the turntable device 10. The process module group 40 includes at least a filling module 41, a capping module 42, and at least one functional module.

[0030] like Figure 2 , Figure 3As shown, at least one process execution station 50 is set on the movement trajectory of the turntable device 10. Structurally, the turntable device 10 includes a rotating drive disk 12 and a fixed support disk 13 arranged at intervals. The outer circumferential edge of the rotating drive disk 12 is provided with a plurality of circumferentially distributed positioning grooves 121. The bottle holder 20 is fitted into the positioning grooves 121 with clearance, and the outer wall of the bottle holder 20 can be reserved with a clearance of 1 to 2 mm between itself and the inner wall of the positioning groove 121. The top surface of the fixed support disk 13 is provided with a raised slide rail 131 extending in the circumferential direction. Correspondingly, the bottom surface of the bottle holder 20 is provided with a bottom groove 22 that slides with the raised slide rail 131.

[0031] There is a non-contact gap between the raised slide rail 131 and the inner wall of the bottom groove 22. In non-processing areas, the bottom groove 22 and the raised slide rail 131 remain in a non-contact state. At this time, the raised slide rail 131 does not bear weight or provide friction guidance; it only serves as an initial positioning element to prevent the bottle holder 20 from deviating from its circumferential trajectory. The actual movement and precise positioning of the bottle holder 20 are achieved by the rotary drive disk 12. Specifically, when the rotary drive disk 12 rotates under the drive mechanism 11, the side wall of the positioning groove 121 abuts against the outer wall of the bottle holder 20. Through this abutment, the rotary drive disk 12 transmits circumferential thrust to the bottle holder 20 and also mechanically limits its movement, forming a stable transmission and limiting cooperation. Under this cooperation, the bottle holder 20 achieves precise positioning through the abutment drive of the side wall and moves smoothly circumferentially with the rotary drive disk 12. This design not only effectively overcomes the defects of rigid vibration transmission and bottom sliding friction interference that are common in traditional equipment, but also avoids the risk of particle shedding due to mechanical friction from a physical source, so as to adapt to the stringent clean production standards of sterile preparation workshops.

[0032] In particular, such as Figure 8 As shown, at the process execution station 50, the raised slide rail 131 on the fixed support plate 13 is partially cut off to form a guide rail notch 132 or a through hole structure. A process execution support member 70, structurally completely independent of the fixed support plate 13, is arranged within the guide rail notch 132. When the rotary drive plate 12 pushes the bottle holder 20 to a position directly above the guide rail notch 132, the bottom groove 22 of the bottle holder 20 completely detaches from the raised slide rail 131, and is instead supported from bottom to top by the process execution support member 70. At this time, thanks to the aforementioned clearance setting, the bottle holder 20 is in a suspended state within the positioning groove 121, where it does not contact the rotary drive plate 12 radially or circumferentially.

[0033] Through the aforementioned spatial avoidance and force conversion structure, the bottle holder 20, when entering the process execution station 50, can achieve complete mechanical decoupling from the turntable device 10, thus entering an absolutely static independent state. In this independent state, when the corresponding module in the process module group 40 performs independent process actions on the packaging material, the mechanical vibrations and stresses generated by the turntable device 10 and the drive mechanism 11 cannot be transmitted to the bottle holder 20 through the rigid medium, thereby ensuring high precision in process execution and zero loss of packaging material. After the process action at this station is completed, the rotary drive disk 12 resumes rotational feed, and the side wall of its positioning groove 121 abuts against the outer side wall of the bottle holder 20 again, pushing the bottle holder 20 out of the guide rail notch 132. During this process, the raised slide rail 131 on the fixed support plate 13 re-extends into the bottom groove 22 of the bottle holder 20 and the two maintain a non-contact gap to restore the initial positioning function of the bottle holder 20, thereby smoothly realizing the recoupling and reset of the kinematic chain.

[0034] In some embodiments, such as Figures 1 to 3 As shown, the contactless transfer and capping system is configured in a first configuration state for processing a first type of packaging material 31. The first type of packaging material 31 is a single-cavity vial or cartridge. In the first configuration state, the process execution station 50 is configured as a weighing station 51, the process module group 40 correspondingly includes a high-precision weighing module 44, and the process execution support 70 is constructed as a weighing tray of the weighing module 44. When the bottle tray 20 moves to the weighing station 51 and enters an independent state, the bottle tray 20 and the packaging material it carries are supported only from bottom to top by the weighing module 44, thereby maintaining a non-contact gap with the other structural components of the turntable device 10. The first type of packaging material 31 maintains an initial unidirectional rotation on the turntable device 10 and sequentially completes the corresponding process steps through the corresponding process execution station 50. Specifically, depending on different production needs, the process steps may include empty bottle weighing, liquid filling by the filling module 41, post-filling weighing, and capping by the capping module 42. It is understood that the above exemplary process steps can be changed in sequence according to the actual production line or product requirements, and are not specifically limited here. Through the aforementioned physically isolated support structure, the weighing module 44 can perform weighing operations in an environment free from external mechanical stress and rigid vibration interference, thereby obtaining high-precision liquid weight data. Furthermore, in specific implementations, depending on the actual product requirements, the first configuration state for processing the first type of packaging material 31 also includes a capping module. This capping module can be located downstream of the capping module 42 on the turntable device 10, or it can be located downstream of the material unloading position of the turntable device 10, depending on the actual production line layout requirements.

[0035] In other embodiments, such as Figures 4 to 6As shown, the contactless transfer and plugging system is also configured in a second configuration state for processing a second type of packaging material 32. The second type of packaging material 32 is a pre-filled dual-chamber syringe that requires different media to be injected into both ends. In the second configuration state, the process execution station 50 includes a first flipping station 52, the functional module includes a first flipping module 45 located at this station, and the process module group 40 further includes a second flipping module 46 located downstream of the first flipping module 45 and a capping module 47 located upstream of the first flipping station 52.

[0036] Specifically, in the second configuration state, the system divides the processing of the second type of packaging material 32 into a first processing stage and a second processing stage according to the actual product's process requirements. It is worth mentioning that this system has a high degree of process flexibility in its architecture design. It is configured to support the packaging material, after completing the first processing stage, either to remain continuously circulating online on the turntable device 10 to directly enter the second processing stage; or, after completing the first processing stage, to be removed from the turntable device 10 by the unloading mechanism for offline processing, such as entering a freeze dryer to perform a batch freeze-drying process, converting the internal liquid medicine into a powder cake state, and then reloading it onto the turntable device 10 to continue the circulation of the second processing stage.

[0037] In the first processing stage (i.e., the pre-processing stage of the first end of the double-cavity packaging material), the system controls the drive mechanism 11 to perform a reverse rotation action, opposite to that when processing single-cavity packaging materials (i.e., the initial rotation direction), such as counterclockwise. The second type of packaging material 32 moves in the opposite direction with the turntable device 10, and while maintaining the initial opening orientation (e.g., opening facing upwards), it passes through the corresponding workstations in sequence to complete the first plugging (adding an intermediate plug) and the first filling process of the first end.

[0038] In the second processing stage (i.e., the second end operation stage of the double-cavity packaging material), the drive mechanism 11 switches its operating logic, driving the turntable device 10 to return to the initial rotation direction in a forward motion, such as clockwise. The packaging material that has undergone the first processing stage, whether it is a continuously circulating packaging material online or a packaging material that has been freeze-dried offline and then reloaded, moves forward with the turntable device 10. First, the capping module 47 performs a capping and sealing operation on the first end of the packaging material; then, when the packaging material enters the first flipping station 52, the gripper mechanism of the first flipping module 45 vertically grips the packaging material downward, extracts it from the bottle holder 20 which is in an independent state, and performs a 180-degree flipping and reorientation operation in the vertical plane, and then vertically inserts it back into the bottle holder 20 to complete the inversion switch of the packaging material opening orientation.

[0039] After being flipped and inverted, the packaging material continues to move forward with the turntable device 10. In this process path, thanks to the system's initial reverse-then-forward motion chain design, the packaging material can reuse the original filling module 41 and stoppering module 42 in the process module group 40 to perform a second filling (e.g., solvent injection) and a second stoppering operation on the second end of the packaging material. After completing the second stoppering operation, the packaging material is fed forward again with the turntable device 10 to the second flipping module 46, where it is picked up and flipped 180 degrees to reset the second type of packaging material 32 to its initial orientation, so that the subsequent unloading mechanism can perform a unified unloading operation.

[0040] Through the aforementioned configuration state switching logic, reverse-then-forward trajectory planning, and streamlined design compatible with offline interruption mechanisms, the same turntable architecture can not only flexibly adapt to the complex process requirements of various packaging materials such as single-cavity and dual-cavity, effectively be compatible with different formulation processes such as liquid-lyophilized powder dual-cavity and liquid-liquid dual-cavity, but also significantly reduce the setting of redundant workstations by reusing processing modules, thereby improving the equipment's versatility while achieving a highly compact overall structure and minimizing the footprint.

[0041] Furthermore, in order to achieve the aforementioned smooth and precise flipping and directional movements, such as Figure 5 As shown, the first flipping module 45 specifically includes a fixed base, a lifting drive mechanism, a rotary drive mechanism, and a clamping assembly in its mechanical structure. The fixed end of the lifting drive mechanism is securely mounted on the fixed base, and its power output end is connected to the rotary drive mechanism. The rotary drive mechanism has a horizontally extending rotary output shaft, which is drively connected to the clamping assembly. During the flipping operation, the clamping assembly first closes radially to clamp the packaging material. Then, the lifting drive mechanism drives the clamping assembly to move vertically upward, pulling the packaging material upward and completely detaching it from the bottle holder 20. Next, the rotary drive mechanism drives the clamping assembly and the clamped packaging material to rotate 180 degrees in the vertical plane. Finally, the lifting drive mechanism moves in the opposite direction downward, vertically inserting the flipped packaging material back into the bottle holder 20 to complete the reorientation. In addition, the mechanical structure of the second flipping module 46 is the same as that of the first flipping module 45. The two are arranged at intervals along the process path of the turntable device 10, respectively responsible for the inversion switching and reset switching of the packaging material, and working together to realize the closed-loop flow operation of the dual-cavity packaging material.

[0042] In some preferred embodiments, such as Figure 4 , Figure 8As shown, to achieve comprehensive, blind-spot-free inspection of the packaging material's appearance and internal media, the process execution station 50 further includes a vision inspection station 53. At the vision inspection station 53, the process execution support 70 is specifically constructed as a rotating support 71, and the functional module correspondingly includes a rotary drive mechanism 48 that is pulverically connected to the rotating support 71.

[0043] In terms of structural fit, a limiting rib 711 is protruding from the top support surface of the rotating support 71. The limiting rib 711 is configured to form a continuous track structure with the raised slide rail 131 on the fixed support plate 13. When the bottle tray 20 is fed to the visual inspection station 53 and cuts into the independent state at the guide rail notch 132, the rotating support 71 moves upward, and its top support surface directly receives and abuts against the bottom surface of the bottle tray 20. Subsequently, the rotating drive mechanism 48 is activated, relying on the bearing friction between the top support surface and the bottom surface of the bottle tray 20 to smoothly drive the bottle tray 20 and the packaging material it carries to perform a 360-degree circumferential rotation. During this circumferential rotation, the limiting rib 711 extends into the bottom groove 22 of the bottom surface of the bottle tray 20, and a non-contact gap is left between the outer wall of the limiting rib 711 and the inner wall of the bottom groove 22. The limiting rib 711 does not transmit rotational driving force, but plays the role of limiting clearance, so as to prevent the bottle holder 20 from having a large positional deviation due to rotational inertia or mechanical vibration during high-speed rotation, thereby ensuring the concentricity and stability of the packaging material during rotation.

[0044] During this smooth circumferential rotation, the vision sensor 60, laterally positioned at the vision inspection station 53, continuously acquires images to obtain complete image data of the circumferential surface of the packaging material. This provides a basis for accurate analysis of the capping position and height, the stopper position, and the state of the freeze-dried powder cake. Understandably, the spatial arrangement of the vision sensor 60 is not limited to the single vision inspection station 53. In actual use, depending on the actual process monitoring needs, the vision sensor 60 can be integrated in an array or flexibly selected manner at various execution nodes of the process module group 40. For example, in an implementation scenario involving the processing of the second type of packaging material 32, the vision sensor 60 can be added off-axis to the station area where the capping module 47 is located to perform real-time online re-inspection of the end of the packaging material after the capping process. This identifies whether the capping position and height, the stopper position, and the state of the freeze-dried powder cake meet preset tolerance thresholds and quality standards, thereby ensuring the overall sealing integrity of the packaging material end and achieving early interception and closed-loop control of production defects.

[0045] In some embodiments, such as Figure 8 As shown, the weighing plate of the weighing module 44 can also be provided with a limiting rib 711 to improve stability.

[0046] In a further embodiment, such as Figure 1 , Figure 5 As shown, the feed end of the contactless transfer and filling system is equipped with a linked feeding mechanism 80. The linked feeding mechanism 80 includes a rotatable nesting tray support platform 81 and a rotatable feeding mechanical clamp 82. The nesting tray support platform 81 is used to support the nesting tray 90 containing matrix-arranged packaging materials. In terms of spatial layout, the vertical rotation axis of the nesting tray support platform 81 and the vertical rotation axis of the feeding mechanical clamp 82 are parallel to each other and maintain a preset center distance, so that the rotation trajectory circles of the two form a geometric intersection point in the spatial plane. In terms of operation logic, the feeding mechanical clamp 82 and the nesting tray support platform 81 perform rotational phase coupling motion. The feeding mechanical clamp 82 can accurately extract the packaging materials at different coordinate positions in the nesting tray 90 one by one at the intersection point of the above trajectory by only rotating around its own axis and lifting in the vertical direction, and smoothly transfer them into the bottle holder 20 of the turntable device 10. This pure rotary coupling transfer mechanism completely eliminates the need for traditional horizontal linear translation guides, effectively reducing the generation of mechanical friction particles and significantly reducing the overall footprint of the equipment.

[0047] In other embodiments, based on the configuration requirements of differentiated process flow lines, such as Figure 2 As shown, the transfer module, which is isomorphically designed with the linked feeding mechanism 80, can be equivalently configured as a linked unloading mechanism and is spatially arranged downstream of the turntable device 10's process flow (i.e., the discharge end). During the unloading operation, the linked unloading mechanism, by invoking motion control logic that is the reverse of the feeding process, utilizes the phase-coupled rotation and lifting motion of its mechanical clamps to precisely extract the finished packaging material that has completed all processing steps from the bottle holder 20 and smoothly unload it into the empty nesting plate on the discharge side. This isomorphic and modular design of the feeding mechanism not only achieves a high degree of standardization of the core components of the entire machine, significantly reducing the manufacturing cost of the equipment and the difficulty of spare parts maintenance, but also ensures the smoothness of the packaging material's movement when entering and exiting the turntable system and the consistency of the entire production line's cycle time.

[0048] In some embodiments, such as Figure 1 , Figure 5As shown, to meet the stringent air quality standards of high-level sterile cleanrooms, the loading mechanical clamp 82 specifically includes a horizontally extending support cantilever 821 and a gripper 822 located at the end of the support cantilever 821. Both the support cantilever 821 and the gripper 822 have vertically penetrating clearance structures 823, which are streamlined perforated grooves or guide holes. In terms of structural and airflow coordination, the clearance structure 823 allows the vertical laminar airflow output from the top of the cleanroom to smoothly penetrate the mechanical clamping components and directly act on the open end of the packaging material. This pneumatic clearance design effectively eliminates the laminar airflow obstruction, airflow vortices, and blind spots caused by traditional wide, translating robotic arms above open packaging materials, completely blocking the risk of environmental particles and microorganisms settling into the packaging material from a physical path.

[0049] In summary, the contactless transfer and capping system for filling multi-specification packaging materials provided in this application innovatively introduces a mechanically decoupled process execution station on the turntable device. This allows the bottle tray to enter a physically isolated independent state when performing key processes, fundamentally eliminating the interference of rigid vibration and sliding friction of the equipment. This ensures extremely high accuracy in micro-weighing and visual inspection, and effectively avoids scratches on the appearance of polymer packaging materials. At the same time, relying on a highly integrated turntable architecture and flexibly switchable operation control logic, combined with a function flipping module and a reverse rotation reuse mechanism, this system is perfectly compatible with unidirectional single-cavity packaging materials and dual-cavity syringes requiring bidirectional processing on the same basic hardware platform. This greatly improves the versatility of the equipment and achieves a compact overall structure and minimizes the workshop floor space. In addition, the feeding mechanism based on pure rotational coupling and the laminar flow wind avoidance design that conforms to fluid dynamics completely eliminates airflow obstruction and particulate vortices above open packaging materials, minimizing the risk of microbial contamination and fully complying with the aseptic production specifications of the new GMP high-level clean areas.

[0050] In the description of this application, it should be noted that the terms "vertical", "up", "down", "horizontal", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application.

[0051] In the description of this application, it should also be noted that, unless otherwise expressly specified and limited, the terms "set up," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0052] Finally, it should be noted that the above description is merely a preferred embodiment of this application and is not intended to limit this application. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. A contactless transfer and capping system for filling multi-specification packaging materials, characterized in that, include: The rotary table device is driven by a drive mechanism to perform rotary feed motion; Multiple bottle holders are distributed circumferentially along the turntable device, and each bottle holder has a positioning structure for carrying packaging materials; A process module group is arranged around the circumference of the turntable device, and the process module group includes at least a filling module, a stoppering module and at least one functional module; The turntable device is provided with at least one process execution station, and the bottle holder is mechanically decoupled from the turntable device to be in an independent state when it enters the process execution station. In the independent state, the corresponding module in the process module group can perform independent process actions for the bottle tray or the packaging material it carries; After the action is completed, the bottle holder is recoupled and reset to the turntable device.

2. The contactless transfer and capping system for filling multi-specification packaging materials according to claim 1, characterized in that, The system has a first configuration state for processing the first type of packaging materials: In the first configuration state, the process execution station includes a weighing station, and the process module group further includes a weighing module; At the weighing station, the bottle tray in the independent state, together with the packaging material it carries, maintains a non-contact gap with the turntable device so that the weighing module can perform the weighing operation. The first type of packaging material maintains its initial rotation direction and flows unidirectionally on the turntable device, and sequentially completes the corresponding process steps through the corresponding process execution station.

3. The contactless transfer and capping system for filling multi-specification packaging materials according to claim 2, characterized in that, The system has a second configuration state for processing the second type of packaging materials: In the second configuration state, the process execution station includes a first flip station, and the functional module includes a first flip module located at the station; At the first flipping station, the first flipping module extracts the packaging material from the bottle tray in the independent state and performs a flipping and reversing action, and then puts it back into the bottle tray to switch the opening orientation of the packaging material.

4. The contactless transfer and capping system for filling multi-specification packaging materials according to claim 3, characterized in that, The process module group also includes a second flipping module located downstream of the first flipping module, and a capping module located upstream of the first flipping station. In the second configuration state, the processing operation of the second type of packaging material includes a first processing stage and a second processing stage: In the first processing stage, the drive mechanism drives the turntable device to perform a reverse rotation action opposite to the initial rotation direction. The packaging material moves in the opposite direction with the turntable device, and the first plugging and first filling process of the first end are completed in sequence while maintaining the initial orientation. In the second processing stage, the drive mechanism drives the turntable device to restore the initial rotation direction in a forward motion. The packaging material that has undergone the first processing stage moves forward with the turntable device. After the capping module performs the capping operation, the first flipping module extracts the packaging material and performs a flipping and reversing operation. After being flipped, the packaging material continues to move forward with the turntable device to reuse the filling module and the stoppering module in the process module group to perform a second filling and a second stoppering operation; then the second flipping module extracts and performs a flipping and reversing action to reset it to the initial orientation; The system is configured to support the packaging material to be continuously rotated online on the turntable device between the first processing stage and the second processing stage, or to be reloaded onto the turntable device for rotation after offline unloading.

5. The contactless transfer and capping system for filling multi-specification packaging materials according to claim 2, 3, or 4, characterized in that, The process execution station also includes a vision inspection station, and the functional module includes a rotary drive mechanism located at the station. At the vision inspection station, the rotary drive mechanism is mechanically coupled to the bottle holder in an independent state and drives the bottle holder and the packaging material it carries to rotate circumferentially so that the laterally arranged vision sensor can acquire image data of the circumferential surface of the packaging material.

6. The contactless transfer and capping system for filling multi-specification packaging materials according to claim 1, characterized in that, The turntable device includes a rotating drive disc and a fixed support disc arranged at intervals. The rotating drive disc has multiple circumferentially distributed positioning grooves. The bottle holder is placed in the positioning grooves, and there is a clearance between its side wall and the inner wall of the positioning groove. The surface of the fixed support disc has a circumferentially extending raised slide rail. The bottom surface of the bottle holder has a bottom groove into which the raised slide rail extends. There is a non-contact gap between the raised slide rail and the inner wall of the bottom groove. In non-process execution positions, the rotating drive disc rotates so that the side wall of the positioning groove abuts against the outer wall of the bottle holder to form a transmission and limiting engagement, thereby driving the bottle holder to move circumferentially with the rotating drive disc.

7. The contactless transfer and capping system for filling multi-specification packaging materials according to claim 6, characterized in that, The fixed support plate at the process execution station is provided with a guide rail notch, and a process execution support component is provided in the guide rail notch, which is independently configured from the fixed support plate. When the bottle holder moves to the guide rail notch, the bottle holder is disengaged from the raised slide rail and is supported by the process execution support component. At this time, the bottle holder is in a radial and circumferential suspended state in the positioning groove, so as to achieve the mechanical decoupling.

8. The contactless transfer and capping system for filling multi-specification packaging materials according to claim 7, characterized in that, The process execution station also includes a vision inspection station; the process execution support at the vision inspection station is a rotating support; the top support surface of the rotating support is provided with a limiting rib, and the rotating support is configured such that: in the independent state, the top support surface supports the bottom surface of the bottle tray upwards to drive the bottle tray to perform circumferential rotation; at the same time, the limiting rib extends into the bottom groove of the bottom surface of the bottle tray and there is a gap between the two to limit the bottle tray during rotation and prevent the bottle tray from having a positional deviation; so that the laterally arranged vision sensor can acquire image data of the circumferential surface of the packaging material.

9. The contactless transfer and capping system for filling multi-specification packaging materials according to claim 1, characterized in that, It also includes a linkage feeding mechanism, which includes a rotatable nesting board support platform and a rotatable feeding mechanical clamp. The rotation axis of the nesting board support platform is parallel to the rotation axis of the feeding mechanical clamp. The feeding mechanical clamp is configured to extract packaging materials at different coordinate positions inside the nesting board and transfer them to the bottle tray by rotating in a phase-coupled motion with the nesting board support platform.

10. The contactless transfer and capping system for filling multi-specification packaging materials according to claim 9, characterized in that, The feeding mechanism includes a support cantilever and a gripper located at the end of the support cantilever. The support cantilever and / or the gripper have a vertically penetrating clearance structure on their bodies. The clearance structure is configured to allow laminar airflow from top to bottom to vertically penetrate and blow toward the opening end of the packaging material.

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