Structural modification based on L-proline as well as synthesis method and application of structural modification based on L-proline

The 2-(diethylamino)ethyl-L-proline ester synthesized through biomimetic molecular design solves the problem of easy degradation of natural amino acids, improves the plant growth regulation activity and duration of effect, and is suitable for the development of green agrochemical products for wheat and soybeans.

CN122355897APending Publication Date: 2026-07-10HIGH & NEW TECH RES CENT OF HENAN ACAD OF SCI
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Patent Information

Application Number
CN202610482142.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-04-13
Publication Date
2026-07-10

AI Technical Summary

Technical Problem

In existing technologies, the natural amino acid L-proline is easily degraded rapidly by enzymes in plants, has a short duration of effect, requires frequent application, and needs further optimization in terms of controllability, diversity, and efficiency.

Method used

A novel compound, 2-(diethylamino)ethyl-L-proline ester, was synthesized using a biomimetic molecular design strategy. A bioactivator based on L-proline structural modification was then prepared by esterification of L-proline with N,N-diethylethanolamine.

Benefits of technology

The synthesized 2-(diethylamino)ethyl-L-proline ester has good water solubility and a long-lasting effect, significantly improving plant growth regulation activity, especially in wheat and soybeans. It avoids residual degradation in the soil and provides a green and environmentally friendly option for the development of agrochemical products.

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Abstract

The invention relates to a biological activator based on L-proline structure modification as well as a synthesis method and application thereof, and belongs to the technical field of agricultural chemistry. The activator is prepared by splicing active structural units by adopting a bionic molecular design strategy, and 2-(diethylamino) ethyl-L-proline ester is obtained by carrying out esterification reaction on unique natural source advantages of L-proline and an important active unit fragment N, N-diethylethanolamine in DA-6. The compound is respectively subjected to biological activity experiments on wheat and soybeans, and results show that the compound can promote plant growth at low concentration, and the growth effects of the compound in the aspects of germination rate, root length and stem length are far superior to those of a blank control. Besides, the preparation process is simple, the cost is low, the industrial production is easy to realize, the environmental compatibility is good, a new choice is provided for the development of the activating agent due to the unique natural source advantage of the activating agent, and the high agricultural development potential is achieved.
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