Early enteral nutrition for postoperative rehabilitation assessment system in patients with abdominal trauma

Abstract

This invention relates to the field of medical data mining technology, specifically to a system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma. First, based on preoperative functional reserve data, patients with abdominal trauma of different severity are clustered. Then, within each patient cluster, the correlation between nutritional recovery is determined based on the correlation between the early enteral nutrition reference level (representing early enteral nutrition absorption) and the degree of intestinal blood regulation (representing abnormalities in postoperative intestinal indicators). Next, based on intestinal fat recording data and postoperative nutrient solution indicators, the fat tolerance influence (representing the impact of fat content on intestinal tolerance) is determined. Thus, by combining the nutritional recovery correlation and the fat tolerance influence, the postoperative rehabilitation effect of patients is comprehensively analyzed from the perspective of early enteral nutrition supply, resulting in a higher accuracy of the postoperative rehabilitation effect assessment value.

Description

Technical Field

[0001] This invention relates to the field of medical data mining technology, specifically to a system for evaluating the postoperative rehabilitation effect of early enteral nutrition on patients with abdominal trauma. Background Technology

[0002] Current technologies assess postoperative recovery outcomes by evaluating the patient's physical condition. However, patients with abdominal trauma often undergo extensive surgery, making their nutritional needs more complex than those of regular patients. The inflammatory response caused by abdominal trauma accelerates nutrient depletion, making appropriate nutritional support crucial for recovery. Inadequate nutrition can negatively impact postoperative recovery. For example, in early enteral nutrition, fat content is a key variable; high-fat formulas may cause diarrhea, while low-fat formulas may lead to insufficient calorie intake. This can result in unsuitable early enteral nutrition for the patient, affecting postoperative recovery. Furthermore, current technologies do not consider the impact of early enteral nutrition on postoperative recovery, leading to lower accuracy in the determined postoperative recovery outcome assessments. Summary of the Invention

[0003] To address the technical problem that existing technologies do not consider the impact of early enteral nutrition on postoperative recovery, resulting in low accuracy of postoperative recovery assessment values, this application aims to provide a system for assessing the postoperative recovery effects of early enteral nutrition in patients with abdominal trauma. The specific technical solution adopted is as follows: The first aspect of this application provides a system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma, including: The data acquisition and preprocessing module is used to acquire preoperative functional reserve data, intraoperative indicator data, postoperative nutritional fluid indicator data, postoperative intestinal indicator data, and intestinal fat record data for each abdominal trauma patient from the medical database; and to divide all abdominal trauma patients into at least two patient clusters based on the preoperative functional reserve data. The first determining module is used to determine the early postoperative enteral nutrition reference level for each abdominal trauma patient based on the distribution of intraoperative indicator data during the operation and the overall size of the postoperative nutritional fluid indicator data; and to determine the degree of postoperative intestinal blood regulation for each abdominal trauma patient based on the upward trend of the postoperative intestinal indicator data. The second determining module is used to determine the corresponding nutritional recovery correlation based on the correlation between the early enteral nutrition supply level and the degree of intestinal blood regulation of all abdominal trauma patients in each patient cluster; and to determine the corresponding fat tolerance influence based on the distribution of changes in intestinal fat recording data and the concentrated distribution of postoperative nutritional fluid index data of all abdominal trauma patients in each patient cluster. The rehabilitation effect assessment module is used to determine the postoperative rehabilitation effect assessment value for each abdominal trauma patient based on the nutritional recovery correlation and the fat tolerance influence.

[0004] Furthermore, the process of acquiring the preoperative functional reserve data includes: Obtain the post-traumatic ISS score and albumin concentration for each patient with abdominal trauma from the medical database; Preoperative functional reserve data for each patient with abdominal trauma were determined based on the normalization of the ratio between the post-traumatic ISS score and the albumin concentration.

[0005] Furthermore, the process of obtaining the early enteral nutrition supply level includes: The corresponding nutrient and energy absorption rate was determined based on the overall blood flow rate and the decreasing trend of lactate concentration during the operation of each abdominal trauma patient. The corresponding postoperative nutritional fluid supply intensity is determined based on the normalized value of the product between the average rate of nutritional fluid supply and the average concentration of nutritional fluid supply for each abdominal trauma patient after surgery. The reference level for early enteral nutrition for each abdominal trauma patient is determined based on the product of the nutrient energy absorption rate and the postoperative nutrient solution supply intensity.

[0006] Furthermore, the process of obtaining the nutrient energy absorption rate includes: The mean blood flow velocity at all sampling moments during the operation of each abdominal trauma patient was normalized to determine the blood flow velocity parameter. The lactate concentration at all sampling moments during the operation of each abdominal trauma patient was arranged in chronological order and then subjected to curve fitting to determine the lactate concentration time-series curve. The mean slope of the tangent line at all sampling moments on the lactate concentration time-series curve was normalized to determine the corresponding lactate change parameter. The corresponding nutrient energy absorption rate was determined based on the product of the negative correlation mapping value of the lactate change parameter and the blood flow velocity parameter.

[0007] Furthermore, the process of obtaining the degree of intestinal blood regulation includes: The serum protein concentrations of each abdominal trauma patient at all sampling times after surgery were arranged in chronological order and curve fitted to determine the serum protein concentration curve; the degree of intestinal blood regulation was determined based on the negative correlation mapping value of the mean slope of the tangent at all sampling times on the serum protein concentration curve.

[0008] Furthermore, the process of obtaining the nutritional restoration correlation includes: Within each patient cluster, the early enteral nutrition reference levels of all patients with abdominal trauma were arranged in chronological order of their registration in the medical database to determine the early enteral nutrition reference level sequence; the intestinal blood regulation degree of all patients with abdominal trauma was arranged in chronological order of their registration in the medical database to determine the intestinal blood regulation degree sequence; and the nutritional recovery correlation of each patient cluster was determined based on the Pearson correlation coefficient between the early enteral nutrition reference level sequence and the intestinal blood regulation degree sequence.

[0009] Furthermore, the process of obtaining the influence of fat tolerance includes: Obtain daily postoperative gastric residual volume and diarrhea frequency data for each abdominal trauma patient; determine intestinal tolerance for each abdominal trauma patient based on the temporal decay of gastric residual volume data and diarrhea frequency. Within each patient cluster, cluster analysis was performed based on the rate and concentration of nutrient solution administration for each abdominal trauma patient, dividing all abdominal trauma patients in each patient cluster into at least two sub-clusters; the fat content parameter was determined based on the mean fat content in enteral nutrition for each abdominal trauma patient at all postoperative sampling times. Within each sub-cluster, the corresponding local tolerance influence is determined based on the relative change trends of intestinal tolerance and early enteral nutrition reference levels in each abdominal trauma patient in the order of fat content parameters from smallest to largest. The corresponding fat tolerance influence is determined based on the mean of the local tolerance influence of all sub-clusters in each patient cluster.

[0010] Furthermore, the process of acquiring intestinal tolerance includes: The gastric residual volume data of each abdominal trauma patient on all postoperative days were arranged in chronological order and curve fitting was performed to determine the gastric residual volume time-series curve. The degree of increase in gastric residual volume was determined based on the normalized value of the mean slope of the tangent line on all days of the gastric residual volume time-series curve. The corresponding intestinal tolerance was determined by negatively mapping the product between the mean number of diarrheas on all postoperative days of each abdominal trauma patient and the degree of increase in gastric residual volume.

[0011] Furthermore, the process of obtaining the local tolerance influence degree includes: In each sub-cluster, the intestinal tolerance of all patients with abdominal trauma was arranged in ascending order of the corresponding fat content parameter and then curve-fitted to determine the corresponding intestinal fat tolerance curve; the early enteral nutrition reference level of all patients with abdominal trauma was arranged in ascending order of the corresponding fat content parameter and then curve-fitted to determine the corresponding early enteral nutrition reference curve. The mean slope of the tangent corresponding to all patients with abdominal trauma on the intestinal fat tolerance curve is negatively correlated to determine the tolerance decrease coefficient of each sub-cluster; the mean slope of the tangent corresponding to all patients with abdominal trauma on the early enteral nutrition reference curve is normalized to determine the supply level increase coefficient of each sub-cluster; the local tolerance influence of each sub-cluster is determined based on the product of the tolerance decrease coefficient and the supply level increase coefficient.

[0012] Furthermore, the process of obtaining the postoperative rehabilitation effect assessment value includes: The product between the negative correlation mapping value of the fat tolerance influence and the nutritional recovery correlation is normalized to determine the fat content recovery weight of each patient cluster. When the fat content recovery weight is greater than or equal to the preset high-fat threshold, the high-fat formula is used as the matching nutritional formula for the corresponding patient cluster; when the fat content recovery weight is greater than or equal to the preset low-fat threshold and less than the preset high-fat threshold, the standard fat formula is used as the matching nutritional formula for the corresponding patient cluster; when the fat content recovery weight is less than the preset low-fat threshold, the low-fat formula is used as the matching nutritional formula for the corresponding patient cluster. Obtain the standard range of fat content in the matching nutritional formula for each patient cluster corresponding to abdominal trauma patients; When the fat content of the early enteral nutrition formula for patients with abdominal trauma is within the corresponding standard range of fat content, the corresponding postoperative rehabilitation effect assessment value is set to 1. When the fat content of the early enteral nutrition formula for patients with abdominal trauma is outside the corresponding standard range of fat content, the difference between the fat content parameter of the abdominal trauma patient and the upper limit of the corresponding standard range of fat content is calculated to determine the first reference difference; the difference between the fat content parameter of the abdominal trauma patient and the lower limit of the corresponding standard range of fat content is calculated to determine the second reference difference; the minimum value between the first reference difference and the second reference difference is negatively correlated to determine the corresponding postoperative rehabilitation effect assessment value for the abdominal trauma patient.

[0013] Secondly, this application provides a computer device including a memory and a processor. The memory is used to store computer program code, and the processor is used to call and run the computer program code from the memory to execute a system as described in the first aspect of this application or any embodiment of the first aspect.

[0014] Thirdly, this application provides a computer program product, which includes computer program code that, when executed, performs a system as described in the first aspect of this application or any embodiment thereof.

[0015] Fourthly, this application provides a computer-readable storage medium that stores computer program code, which, when executed, performs a system as described in the first aspect of this application or any embodiment thereof.

[0016] This application has the following beneficial effects: This application first divides patients with abdominal trauma of different severity based on preoperative functional reserve data. Then, within each patient cluster, the nutritional recovery correlation, which represents the relationship between nutritional level and intestinal recovery, is determined based on the correlation between the early enteral nutrition reference level (characterizing early enteral nutrition absorption) and the degree of intestinal blood regulation (characterizing abnormalities in postoperative intestinal indicators). Subsequently, based on intestinal fat recording data and postoperative nutrient solution indicators, the fat tolerance influence, which represents the impact of fat content on intestinal tolerance, is determined. By combining the nutritional recovery correlation and the fat tolerance influence, the postoperative recovery effect of patients is comprehensively analyzed from the perspective of early enteral nutrition supply, resulting in a more accurate assessment of the postoperative recovery effect. Attached Figure Description

[0017] To more clearly illustrate the technical solutions and advantages in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a structural diagram of a system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma, provided in one embodiment of the present invention. Figure 2 This is a schematic diagram of a computer device structure provided in one embodiment of the present invention. Detailed Implementation

[0019] To further illustrate the technical means and effects adopted by the present invention to achieve its intended purpose, the following, in conjunction with the accompanying drawings and preferred embodiments, details the specific implementation, structure, features, and effects of an early enteral nutrition system for assessing the postoperative rehabilitation effect of abdominal trauma patients according to the present invention. In the following description, different "one embodiment" or "another embodiment" do not necessarily refer to the same embodiment, and specific features, structures, or characteristics in one or more embodiments can be combined in any suitable form. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as implying or suggesting relative importance or implicitly indicating the number of indicated technical features. Thus, a feature defined with "first" or "second" may explicitly or implicitly include one or more of that feature.

[0020] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains.

[0021] The following description, in conjunction with the accompanying drawings, details the specific scheme of the early enteral nutrition system for evaluating the postoperative rehabilitation effect of abdominal trauma patients provided by this invention.

[0022] This application provides a system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma. Please refer to [link to relevant documentation]. Figure 1 The diagram shows a structural diagram of a system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma, according to an embodiment of the present invention. The system includes: a data acquisition and preprocessing module 101, a first determination module 102, a second determination module 103, and a rehabilitation effect evaluation module 104.

[0023] The data acquisition and preprocessing module 101 is used to acquire preoperative functional reserve data, intraoperative indicator data, postoperative nutritional fluid indicator data, postoperative intestinal indicator data, and intestinal fat record data for each abdominal trauma patient from the medical database; and to divide all abdominal trauma patients into at least two patient clusters based on the preoperative functional reserve data.

[0024] Early enteral nutrition refers to the method of providing nutritional support to patients through the intestinal route within 48 hours after surgery. Therefore, in this embodiment of the invention, the data collection range for postoperative nutrient solution index data and postoperative intestinal index data that are directly related to early enteral nutrition is within 48 hours after surgery.

[0025] In one specific implementation of this invention, the process of acquiring preoperative functional reserve data includes: acquiring the post-traumatic ISS score and albumin concentration for each abdominal trauma patient from the hospital's electronic medical record system in the medical database; and determining the preoperative functional reserve data for each abdominal trauma patient based on the normalized ratio between the post-traumatic ISS score and albumin concentration. A higher post-traumatic ISS score indicates a greater degree of abdominal trauma. The preoperative albumin concentration in the patient's body is mainly used to maintain and assist in intraoperative and postoperative fluid management, and to prevent or treat complications caused by insufficient protein. Therefore, a higher preoperative albumin concentration and a lower post-traumatic ISS score indicate better preoperative functional reserve for the corresponding abdominal trauma patient, and thus a larger preoperative functional reserve data. It should be noted that the post-traumatic ISS score and albumin concentration in this embodiment of the invention are normalized data. The normalization method used is min-max normalization to reduce the influence of dimensions on the calculation process.

[0026] In one specific implementation of this invention, the process of dividing all abdominal trauma patients into at least two patient clusters based on preoperative functional reserve data includes: performing cluster analysis on the preoperative functional reserve data of all abdominal trauma patients using the K-means clustering algorithm to determine at least two patient clusters, wherein the K value of the K-means clustering algorithm is determined by the elbow method; and both the K-means clustering algorithm and the elbow method are well known to those skilled in the art, and will not be further limited or described here.

[0027] In one specific implementation of this invention, the intraoperative indicator data during the surgery includes: blood flow velocity data and lactate concentration data of intestinal blood at each sampling time for each abdominal trauma patient during the surgery, with the corresponding sampling frequency set to be collected once per second.

[0028] In one specific implementation of this invention, the postoperative nutritional fluid index data includes: the nutritional fluid supply rate and nutritional fluid concentration at each sampling time within 48 hours postoperatively for each abdominal trauma patient; wherein the unit of nutritional fluid supply rate is ml / h, the nutritional fluid supply concentration is kcal / ml, and the sampling frequency is set to collect data once per hour; the mean of the nutritional fluid supply rate at all corresponding sampling times is normalized to determine the average nutritional fluid supply rate; the mean of the nutritional fluid supply concentration at all corresponding sampling times is normalized to determine the average nutritional fluid supply concentration; the normalization method adopts the minimum-maximum normalization method.

[0029] In one specific implementation of this invention, the postoperative intestinal indicator data includes: the serum protein concentration of each abdominal trauma patient at each sampling time within 48 hours after surgery, with the sampling frequency set to once per second.

[0030] In one specific implementation of this invention, the intestinal fat recording data includes: gastric residual volume and diarrhea frequency data for each abdominal trauma patient per day after surgery, and fat content in enteral nutrition at each sampling time within 48 hours after surgery; wherein, the sampling frequency of fat content in enteral nutrition is set to be once per second, and the fat content in enteral nutrition is obtained by the ratio between the calories of fat at each sampling time in early enteral nutrition and the calories of enteral nutrition.

[0031] It should be noted that the data on the nutrient solution supply rate, nutrient solution concentration, and fat content in the enteral nutrition during the early stages of enteral nutrition were all collected using a total enteral nutrition method, which is a technique well-known to those skilled in the art and will not be further limited or elaborated upon here. Furthermore, unless otherwise specified, all data collected in the embodiments of this invention are normalized data to reduce the influence of dimensions on the calculation process. The normalization method used is the minimum-maximum normalization method, which will not be further elaborated upon here.

[0032] The first determining module 102 is used to determine the early postoperative enteral nutrition reference level for each abdominal trauma patient based on the distribution of intraoperative indicator data and the overall size of postoperative nutrient solution indicator data; and to determine the degree of intestinal blood regulation for each abdominal trauma patient based on the upward trend of postoperative intestinal indicator data.

[0033] For each patient with abdominal trauma, a stronger capacity for nutrient and energy absorption and a higher level of postoperative nutritional fluid supply indicate a higher level of early enteral nutrition absorption. Conversely, poor intestinal blood flow during surgery typically reflects poor postoperative digestive function. Furthermore, an upward trend in intestinal lactate levels usually indicates a strong intestinal stress response during surgery, resulting in poorer nutrient and energy absorption. In addition, postoperative nutritional fluid indicators reflect the level of nutritional fluid supply. Therefore, this embodiment of the invention determines the early postoperative enteral nutrition reference level for each patient with abdominal trauma based on the distribution of intraoperative indicators and the overall magnitude of postoperative nutritional fluid indicators.

[0034] Preferably, in some possible implementations of the embodiments of the present invention, the process of obtaining the early enteral nutrition supply level includes: The nutritional energy absorption rate is determined based on the overall blood flow velocity and the decreasing trend of lactic acid concentration during the operation of each abdominal trauma patient. In a specific implementation of this invention, the process of obtaining the nutritional energy absorption rate includes: normalizing the mean blood flow velocity at all sampling times during the operation of each abdominal trauma patient to determine the blood flow velocity parameter; the higher the blood flow velocity parameter, the better the blood flow in the intestines during the operation of the abdominal trauma patient, and the stronger the corresponding postoperative digestive function, that is, the higher the nutritional energy absorption rate should be.

[0035] Lactate concentration data at all sampling points during the surgical procedure for each abdominal trauma patient were arranged chronologically and subjected to curve fitting to determine a lactate concentration time-series curve. The mean slope of the tangent line at all sampling points on the lactate concentration time-series curve was normalized to determine the corresponding lactate change parameter. It should be noted that the curve fitting method used in all embodiments of this invention employs the least squares method, which can be adjusted according to the specific implementation environment. A larger lactate change parameter indicates a more pronounced upward trend in the lactate concentration time-series curve, a stronger intestinal stress response during surgery, and consequently, a poorer capacity for nutrient and energy absorption, meaning a lower nutrient and energy absorption rate.

[0036] Therefore, based on the correlation, the corresponding nutrient energy absorption rate is determined by multiplying the negative correlation mapping value of the lactate change parameter with the blood flow velocity parameter; thus, the greater the nutrient energy absorption rate, the stronger the nutrient energy absorption capacity of the intestines of patients with abdominal trauma.

[0037] Postoperative nutritional fluid indicators typically reflect the rate and concentration of nutrient fluid administration. A faster rate and higher concentration indicate a higher level of nutrient fluid administration. Therefore, this embodiment of the invention determines the corresponding postoperative nutritional fluid administration intensity based on the normalized value of the product between the average rate and average concentration of nutrient fluid administration for each abdominal trauma patient after surgery. This ensures that a higher postoperative nutritional fluid administration intensity corresponds to a higher level of nutrient fluid administration.

[0038] For each patient with abdominal trauma, the stronger their ability to absorb nutrients and the higher the level of nutrient solution supply, the higher their level of enteral nutrition absorption in the early postoperative period. Therefore, based on the correlation, the reference level of enteral nutrition for each patient with abdominal trauma in the early postoperative period is determined by multiplying the nutrient absorption rate and the intensity of postoperative nutrient solution supply.

[0039] In one specific implementation of this invention, the process of obtaining early enteral nutrition reference levels is expressed by the following formula: ;in, For patients with abdominal trauma Early enteral nutrition reference levels; For patients with abdominal trauma The mean blood flow velocity at all sampling points during the surgery. It is a minimum-maximum normalization function. For patients with abdominal trauma Blood flow velocity parameters; For patients with abdominal trauma The normalized value of the mean slope of the tangent line at all sampling times on the lactate concentration time-series curve, which is also the lactate change parameter; It is an exponential function with the natural constant as its base; For patients with abdominal trauma Average rate of postoperative nutrient fluid supply; For patients with abdominal trauma Average concentration of postoperative nutrient solution; For patients with abdominal trauma The corresponding intensity of postoperative nutritional fluid supply; For patients with abdominal trauma Nutritional energy absorption rate.

[0040] Early enteral nutrition during the postoperative recovery phase can affect the recovery of the intestines; the impact may vary among different patients, thus requiring consideration of the intestinal blood flow status under the patient's early enteral nutrition level. Early enteral nutrition for abdominal trauma patients provides energy and nitrogen, which can improve immune function indicators and increase serum protein concentration by reducing inflammatory cutoff levels. If the serum protein concentration rises slowly, it indicates poorer intestinal blood flow regulation. Therefore, this embodiment of the invention determines the degree of intestinal blood flow regulation for each abdominal trauma patient based on the upward trend of postoperative intestinal indicator data.

[0041] Preferably, in some possible implementations of the embodiments of the present invention, the process of obtaining the degree of intestinal blood regulation includes: Serum protein concentrations at all sampling times post-surgery for each abdominal trauma patient were arranged chronologically and curve-fitted to determine the serum protein concentration curve. The degree of intestinal blood regulation was determined based on the negative correlation mapping value of the mean slope of the tangent line at all sampling times on the serum protein concentration curve. For all sampling times, a smaller overall tangent slope indicates a slower rise in serum protein concentration, corresponding to poorer intestinal blood regulation in the patient; therefore, a greater degree of intestinal blood regulation indicates better intestinal blood regulation.

[0042] The second determining module 103 is used to determine the corresponding nutritional recovery correlation based on the correlation between the early enteral nutrition supply level and the degree of intestinal blood regulation of all abdominal trauma patients in each patient cluster; and to determine the corresponding fat tolerance influence based on the distribution of changes in intestinal fat recording data and the concentrated distribution of postoperative nutritional fluid index data of all abdominal trauma patients in each patient cluster.

[0043] For all abdominal trauma patients in each patient cluster, if there is a high correlation between early enteral nutrition reference level and intestinal blood regulation, it indicates that intestinal recovery is strongly correlated with enteral nutrition level, that is, the higher the enteral nutrition supply level, the better the intestinal recovery.

[0044] Furthermore, it is necessary to consider that fat content has a significant impact on calories, but different abdominal trauma patients have different intestinal tolerance. For example, high-fat formulas have a higher fat content and provide a greater increase in calories. When selecting a high-fat formula, abdominal trauma patients are usually required to have a high tolerance for fat, meaning that the fat content has a smaller impact on intestinal tolerance. In addition, high-fat formulas usually have a high calorie level. If the nutritional recovery of abdominal trauma patients is highly relevant, the high nutritional supply of high-fat formulas will promote intestinal blood regulation, thereby improving the intestinal recovery effect. Therefore, for each abdominal trauma patient, the higher the tolerance for fat and the greater the nutritional recovery, the more suitable a high-fat formula is.

[0045] When analyzing the impact of fat content on intestinal tolerance, it is necessary to combine intestinal fat recording data. Considering that different abdominal trauma patients may have different postoperative nutritional fluid index data characteristics, in order to control variables, it is necessary to combine intestinal fat recording data with postoperative nutritional fluid index data for analysis. Therefore, this embodiment of the invention determines the corresponding fat tolerance influence degree based on the distribution of changes in intestinal fat recording data of all abdominal trauma patients in each patient cluster and the concentrated distribution of postoperative nutritional fluid index data. The greater the corresponding fat tolerance influence degree, the less suitable a high-fat formula is.

[0046] Preferably, in a specific implementation of this invention, the process of obtaining the influence of fat tolerance includes: The study aimed to obtain daily postoperative gastric residual volume and diarrhea frequency data for each abdominal trauma patient; and to determine the intestinal tolerance of each abdominal trauma patient based on the temporal decay of the gastric residual volume data and diarrhea frequency. The process of obtaining intestinal tolerance included: arranging the gastric residual volume data of each abdominal trauma patient in chronological order for all postoperative days and performing curve fitting to determine the gastric residual volume time-series curve.

[0047] First, intestinal intolerance manifests as an increase in gastric residual volume and a higher frequency of diarrhea. The degree of increase in gastric residual volume is determined by the normalized value of the mean slope of the tangent line on the time-series curve of gastric residual volume for all days. Then, a negative correlation is established between the product of the mean number of diarrheas on all days after surgery and the degree of increase in gastric residual volume for each abdominal trauma patient to determine the corresponding intestinal tolerance. As a result, a higher level of intestinal tolerance is characterized by a more significant decreasing trend in gastric residual volume and fewer diarrheas.

[0048] In one specific implementation of this invention, the process of acquiring intestinal tolerance is expressed by the following formula: ;in, For patients with abdominal trauma Intestinal tolerance; For patients with abdominal trauma The mean slope of the tangent line on the time-series curve of gastric residual amount for all days; For patients with abdominal trauma The mean number of diarrhea episodes on all days post-surgery.

[0049] Within each patient cluster, cluster analysis is performed based on the nutrient solution infusion rate and concentration for each abdominal trauma patient, dividing all abdominal trauma patients in each cluster into at least two sub-clusters. In a specific implementation of this invention, a Cartesian coordinate system is constructed with nutrient solution infusion rate as the horizontal axis and nutrient solution concentration as the vertical axis to determine the data point positions of all abdominal trauma patients in each patient cluster within the Cartesian coordinate system. Cluster analysis is then performed on all data points, thereby dividing all abdominal trauma patients in each patient cluster into at least two sub-clusters. The cluster analysis method used is k-means clustering, and the K value is determined using the elbow method, which will not be further elaborated here. Abdominal trauma patients within sub-clusters have similar nutrient solution infusion rates and concentrations; therefore, when performing fat influence analysis within the same sub-cluster, the influence of other factors can be minimized.

[0050] The fat content parameter was determined based on the average fat content in enteral nutrition at all sampling times after surgery for each abdominal trauma patient. The higher the fat content parameter, the higher the proportion of fat energy supplied by the enteral nutrition formula received by the corresponding abdominal trauma patient, and the more calories in the nutrient solution came from the fat component.

[0051] Within each sub-cluster, the corresponding local tolerance influence was determined based on the relative trends of intestinal tolerance and early enteral nutrition reference levels in ascending order of fat content among patients with abdominal trauma. The process of obtaining the local tolerance influence included: Within each sub-cluster, the intestinal tolerance of all abdominal trauma patients was arranged in ascending order of corresponding fat content parameters, and curve fitting was performed to determine the corresponding intestinal fat tolerance curve; the early enteral nutrition reference levels of all abdominal trauma patients were arranged in ascending order of corresponding fat content parameters, and curve fitting was performed to determine the corresponding early enteral nutrition reference curve.

[0052] The intestinal fat tolerance curve can show the trend of intestinal tolerance changes in abdominal trauma patients with increased fat content parameters corresponding to sub-clusters. The more significant the overall downward trend, the greater the impact of fat changes on intestinal tolerance in the corresponding sub-clusters of abdominal trauma patients. Therefore, this embodiment of the invention further performs negative correlation mapping on the mean slope of the tangent line corresponding to all abdominal trauma patients on the intestinal fat tolerance curve to determine the tolerance reduction coefficient of each sub-cluster, so that the larger the tolerance reduction coefficient, the greater the local tolerance influence.

[0053] Early enteral nutrition reference curves can show the changing trend of early enteral nutrition reference levels for abdominal trauma patients corresponding to sub-clusters, as the fat content parameter increases. Since fat is a high-energy-density nutrient, a significant upward trend in the curve indicates that increasing fat content effectively improves the overall nutritional supply level of patients, resulting in higher caloric gains. Therefore, the mean slope of the tangent line corresponding to all abdominal trauma patients on the early enteral nutrition reference curves is normalized to determine the supply level increase coefficient for each sub-cluster. If the supply level increase coefficient is small, meaning that the increase in fat content only brings a slight improvement in nutritional supply but leads to a sharp deterioration in intestinal tolerance, it indicates that this patient group is very sensitive to fat, and the negative impact of fat far outweighs its positive effects; a larger value should be taken for the local tolerance impact. Conversely, if the supply level increase coefficient is large, increasing fat can significantly improve nutritional supply with minimal impact on tolerance, indicating that this patient group can well tolerate high-fat formulas; a smaller value should be taken for the local tolerance impact.

[0054] Therefore, based on the correlation, the local tolerance influence of each sub-cluster is determined by multiplying the tolerance decrease coefficient with the supply level increase coefficient. A higher local tolerance influence indicates a greater impact of fat content on intestinal tolerance in the corresponding sub-cluster of abdominal trauma patients. Finally, a comprehensive analysis is performed by combining the local tolerance influence of all sub-clusters within each patient cluster. Based on the mean of the local tolerance influence of all sub-clusters within each patient cluster, the corresponding fat tolerance influence is determined. A higher fat tolerance influence indicates a more suitable high-fat formula.

[0055] In one specific implementation of this invention, the process of obtaining the influence of fat tolerance is expressed by the following formula: ;in, For the first The impact of fat tolerance on individual patient clusters; For the first The number of sub-clusters in each patient cluster; For the first In the patient cluster, the first The mean slope of the tangent line corresponding to all patients with abdominal trauma on the intestinal fat tolerance curve of each sub-cluster. For the first In the patient cluster, the first The tolerance degradation coefficient of individual sub-clusters; For the first In the patient cluster, the first The mean slope of the tangent line corresponding to all patients with abdominal trauma on the early enteral nutrition reference curve of each sub-cluster. For the first In the patient cluster, the first The supply level increase coefficient of individual clusters; For the first In the patient cluster, the first Local tolerance to influence of individual clusters.

[0056] The rehabilitation effect assessment module 104 is used to determine the postoperative rehabilitation effect assessment value for each abdominal trauma patient based on the nutritional recovery correlation and the fat tolerance influence.

[0057] The greater the correlation with nutritional recovery and the smaller the impact of fat tolerance, the more suitable a high-fat formula is; conversely, the smaller the correlation with nutritional recovery and the greater the impact of fat tolerance, the less suitable a high-fat formula is. Therefore, the suitability of a high-fat formula, characterized by the correlation with nutritional recovery and the impact of fat tolerance, can be further combined with the fat content in the early enteral nutrition formula for patients with abdominal trauma to determine the corresponding postoperative rehabilitation effect assessment value.

[0058] Preferably, in some possible implementations of the embodiments of the present invention, the process of obtaining the postoperative rehabilitation effect assessment value includes: Since a greater correlation between nutritional recovery and a smaller influence of fat tolerance, a high-fat formula is more suitable, this embodiment of the invention normalizes the product between the negative correlation mapping value of fat tolerance and the correlation between nutritional recovery to determine the fat content recovery weight for each patient cluster. This makes a higher fat content recovery weight more suitable for a high-fat formula, i.e., a formula with a higher fat content. Therefore, the appropriate fat content nutritional formula for each patient cluster can be determined based on the magnitude of the fat content recovery weight.

[0059] When the fat content recovery weight is greater than or equal to a preset high-fat threshold, the high-fat formula is used as the matching nutritional formula for the corresponding patient cluster; when the fat content recovery weight is greater than or equal to a preset low-fat threshold and less than a preset high-fat threshold, the standard fat formula is used as the matching nutritional formula for the corresponding patient cluster; when the fat content recovery weight is less than a preset low-fat threshold, the low-fat formula is used as the matching nutritional formula for the corresponding patient cluster. In a specific implementation of this invention, the fat content of the high-fat formula is greater than 30%, the fat content of the standard fat formula is 20%-30%, and the fat content of the low-fat formula is less than 20%; and the preset low-fat threshold is set to 0.4 and the preset high-fat threshold is set to 0.7 in this embodiment, which can be adjusted according to the specific implementation environment, and will not be further elaborated here. Since the patient cluster division in this embodiment relies on preoperative data, for new abdominal trauma patients, the corresponding patient cluster can be determined preoperatively, thereby determining the corresponding matching nutritional formula.

[0060] For each abdominal trauma patient, a significant deviation between the fat content of their customized early enteral nutrition formula and the matching formula for their corresponding patient cluster indicates that the early enteral nutrition formula does not meet their needs, and the corresponding surgical recovery outcome is usually poor. Therefore, based on this characteristic, the standard range of fat content in the matching formula for each abdominal trauma patient's corresponding patient cluster is first obtained. When the fat content of the early enteral nutrition formula for an abdominal trauma patient falls within the corresponding standard range, the corresponding postoperative recovery outcome assessment value is set to 1. If it falls within the corresponding standard range, it indicates that the early enteral nutrition formula meets the expected fat content, and the patient's subsequent surgical recovery outcome is usually good. Here, the early enteral nutrition formula refers to the nutritional formula for the abdominal trauma patient prior to the analysis.

[0061] When the fat content of the early enteral nutrition formula for patients with abdominal trauma is outside the corresponding standard range, the difference between the fat content parameter of the abdominal trauma patient and the upper limit of the corresponding standard range is calculated to determine the first reference difference; the difference between the fat content parameter of the abdominal trauma patient and the lower limit of the corresponding standard range is calculated to determine the second reference difference; the minimum value between the first and second reference differences is negatively correlated to determine the corresponding postoperative recovery assessment value for the abdominal trauma patient. In other words, the greater the deviation of the fat content of the early enteral nutrition formula for abdominal trauma patients from the corresponding standard range, the less the early enteral nutrition formula meets the expected fat content, the worse the patient's subsequent surgical recovery, and the lower the corresponding postoperative recovery assessment value should be.

[0062] In one specific implementation of this invention, the process of negatively correlated mapping of the minimum value between the first reference difference and the second reference difference includes: normalizing the minimum value between the first reference difference and the second reference difference using a minimum-maximum-maximum method to determine a deviation reference value; and using the difference between the real number 1 and the deviation reference value as the corresponding negatively correlated value, which is also the corresponding postoperative rehabilitation effect evaluation value. It should be noted that, to ensure the completeness of the embodiments, the upper limit of the fat content standard range for the high-fat formula in this embodiment is set to 80%, and the lower limit of the fat content standard range for the low-fat formula is set to 0, which can be adjusted according to the specific implementation environment.

[0063] In summary, a system for assessing the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma first divides patients into clusters based on preoperative functional reserve data to determine the severity of abdominal trauma. Then, within each cluster, the system determines the nutritional recovery correlation, representing the relationship between nutritional levels and intestinal recovery, based on the correlation between the early enteral nutrition reference level (indicating early enteral nutrition absorption) and the degree of intestinal blood regulation (indicating abnormalities in postoperative intestinal indicators). Next, based on intestinal fat recording data and postoperative nutrient solution indicators, the system determines the fat tolerance influence, representing the impact of fat content on intestinal tolerance. By combining the nutritional recovery correlation and the fat tolerance influence, the system comprehensively analyzes the postoperative rehabilitation effect of patients across the dimensions of early enteral nutrition supply, resulting in a more accurate assessment of the postoperative rehabilitation effect.

[0064] This application also provides a computer device; please refer to [link / reference]. Figure 2 The diagram illustrates a computer device structure according to an embodiment of the present invention. The computer device includes a memory 201, a processor 202, and a computer program 203 stored in the memory 201 and running on the processor 202. When the processor 202 executes the computer program 203, the computer device can execute any of the aforementioned early enteral nutrition postoperative rehabilitation effect assessment systems for patients with abdominal trauma.

[0065] This application also provides a computer program product that, when run on a computer device, enables the computer device to execute any of the aforementioned early enteral nutrition postoperative rehabilitation effect assessment systems for patients with abdominal trauma.

[0066] This application also provides a computer-readable storage medium storing computer program code. When the computer program code is run on a computer device, the computer device can execute any of the aforementioned early enteral nutrition postoperative rehabilitation effect assessment systems for patients with abdominal trauma.

[0067] In the embodiments provided in this application, it should be understood that the computer device, computer program product and computer-readable storage medium provided are all used to execute the corresponding system provided above, and therefore the beneficial effects they can achieve can be referred to the beneficial effects of the system provided above, which will not be repeated here.

[0068] It should be noted that the order of the above embodiments of the present invention is merely for descriptive purposes and does not represent the superiority or inferiority of the embodiments. The processes depicted in the accompanying drawings do not necessarily require a specific or sequential order to achieve the desired result. In some embodiments, multitasking and parallel processing are also possible or may be advantageous.

[0069] The various embodiments in this specification are described in a progressive manner. The same or similar parts between the various embodiments can be referred to each other. Each embodiment focuses on describing the differences from other embodiments.

Claims

1. A system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma, characterized in that, The system includes: The data acquisition and preprocessing module is used to acquire preoperative functional reserve data, intraoperative indicator data, postoperative nutritional fluid indicator data, postoperative intestinal indicator data, and intestinal fat record data for each abdominal trauma patient from the medical database; and to divide all abdominal trauma patients into at least two patient clusters based on the preoperative functional reserve data. The first determining module is used to determine the early postoperative enteral nutrition reference level for each abdominal trauma patient based on the distribution of intraoperative indicator data during the operation and the overall size of the postoperative nutritional fluid indicator data; and to determine the degree of postoperative intestinal blood regulation for each abdominal trauma patient based on the upward trend of the postoperative intestinal indicator data. The second determining module is used to determine the corresponding nutritional recovery correlation based on the correlation between the early enteral nutrition supply level and the degree of intestinal blood regulation of all abdominal trauma patients in each patient cluster; and to determine the corresponding fat tolerance influence based on the distribution of changes in intestinal fat recording data and the concentrated distribution of postoperative nutritional fluid index data of all abdominal trauma patients in each patient cluster. The rehabilitation effect assessment module is used to determine the postoperative rehabilitation effect assessment value for each abdominal trauma patient based on the nutritional recovery correlation and the fat tolerance influence.

2. The system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma according to claim 1, characterized in that, The process of acquiring the preoperative functional reserve data includes: Obtain the post-traumatic ISS score and albumin concentration for each patient with abdominal trauma from the medical database; Preoperative functional reserve data for each patient with abdominal trauma were determined based on the normalization of the ratio between the post-traumatic ISS score and the albumin concentration.

3. The system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma according to claim 1, characterized in that, The process of obtaining the early enteral nutrition level includes: The corresponding nutrient and energy absorption rate was determined based on the overall blood flow rate and the decreasing trend of lactate concentration during the operation of each abdominal trauma patient. The corresponding postoperative nutritional fluid supply intensity is determined based on the normalized value of the product between the average rate of nutritional fluid supply and the average concentration of nutritional fluid supply for each abdominal trauma patient after surgery. The reference level for early enteral nutrition for each abdominal trauma patient is determined based on the product of the nutrient energy absorption rate and the postoperative nutrient solution supply intensity.

4. The system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma according to claim 3, characterized in that, The process of obtaining the nutrient energy absorption rate includes: The mean blood flow velocity at all sampling moments during the operation of each abdominal trauma patient was normalized to determine the blood flow velocity parameter. The lactate concentration at all sampling moments during the operation of each abdominal trauma patient was arranged in chronological order and then subjected to curve fitting to determine the lactate concentration time-series curve. The mean slope of the tangent line at all sampling moments on the lactate concentration time-series curve was normalized to determine the corresponding lactate change parameter. The corresponding nutrient energy absorption rate was determined based on the product of the negative correlation mapping value of the lactate change parameter and the blood flow velocity parameter.

5. The system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma according to claim 1, characterized in that, The process of obtaining the degree of intestinal blood regulation includes: The serum protein concentrations of each abdominal trauma patient at all sampling times after surgery were arranged in chronological order and curve fitted to determine the serum protein concentration curve; the degree of intestinal blood regulation was determined based on the negative correlation mapping value of the mean slope of the tangent at all sampling times on the serum protein concentration curve.

6. The system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma according to claim 1, characterized in that, The process of obtaining the correlation between nutritional recovery includes: Within each patient cluster, the early enteral nutrition reference levels of all patients with abdominal trauma were arranged in chronological order of their registration in the medical database to determine the early enteral nutrition reference level sequence; the intestinal blood regulation degree of all patients with abdominal trauma was arranged in chronological order of their registration in the medical database to determine the intestinal blood regulation degree sequence; and the nutritional recovery correlation of each patient cluster was determined based on the Pearson correlation coefficient between the early enteral nutrition reference level sequence and the intestinal blood regulation degree sequence.

7. The system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma according to claim 3, characterized in that, The process of obtaining the influence of fat tolerance includes: Obtain daily postoperative gastric residual volume and diarrhea frequency data for each abdominal trauma patient; determine intestinal tolerance for each abdominal trauma patient based on the temporal decay of gastric residual volume data and diarrhea frequency. Within each patient cluster, cluster analysis was performed based on the rate and concentration of nutrient solution administration for each abdominal trauma patient, dividing all abdominal trauma patients in each patient cluster into at least two sub-clusters; the fat content parameter was determined based on the mean fat content in enteral nutrition for each abdominal trauma patient at all postoperative sampling times. Within each sub-cluster, the corresponding local tolerance influence is determined based on the relative change trends of intestinal tolerance and early enteral nutrition reference levels in each abdominal trauma patient in the order of fat content parameters from smallest to largest. The corresponding fat tolerance influence is determined based on the mean of the local tolerance influence of all sub-clusters in each patient cluster.

8. The system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma according to claim 7, characterized in that, The process of acquiring intestinal tolerance includes: The gastric residual volume data of each abdominal trauma patient on all postoperative days were arranged in chronological order and curve fitting was performed to determine the gastric residual volume time-series curve. The degree of increase in gastric residual volume was determined based on the normalized value of the mean slope of the tangent line on all days of the gastric residual volume time-series curve. The corresponding intestinal tolerance was determined by negatively mapping the product between the mean number of diarrheas on all postoperative days of each abdominal trauma patient and the degree of increase in gastric residual volume.

9. A system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma according to claim 7, characterized in that, The process of obtaining the local tolerance influence includes: In each sub-cluster, the intestinal tolerance of all patients with abdominal trauma was arranged in ascending order of the corresponding fat content parameter and then curve-fitted to determine the corresponding intestinal fat tolerance curve; the early enteral nutrition reference level of all patients with abdominal trauma was arranged in ascending order of the corresponding fat content parameter and then curve-fitted to determine the corresponding early enteral nutrition reference curve. The mean slope of the tangent corresponding to all patients with abdominal trauma on the intestinal fat tolerance curve is negatively correlated to determine the tolerance decrease coefficient of each sub-cluster; the mean slope of the tangent corresponding to all patients with abdominal trauma on the early enteral nutrition reference curve is normalized to determine the supply level increase coefficient of each sub-cluster; the local tolerance influence of each sub-cluster is determined based on the product of the tolerance decrease coefficient and the supply level increase coefficient.

10. A system for evaluating the postoperative rehabilitation effect of early enteral nutrition in patients with abdominal trauma according to claim 7, characterized in that, The process of obtaining the postoperative rehabilitation effect assessment value includes: The product between the negative correlation mapping value of the fat tolerance influence and the nutritional recovery correlation is normalized to determine the fat content recovery weight of each patient cluster. When the fat content recovery weight is greater than or equal to the preset high-fat threshold, the high-fat formula is used as the matching nutritional formula for the corresponding patient cluster; when the fat content recovery weight is greater than or equal to the preset low-fat threshold and less than the preset high-fat threshold, the standard fat formula is used as the matching nutritional formula for the corresponding patient cluster; when the fat content recovery weight is less than the preset low-fat threshold, the low-fat formula is used as the matching nutritional formula for the corresponding patient cluster. Obtain the standard range of fat content in the matching nutritional formula for each patient cluster corresponding to abdominal trauma patients; When the fat content of the early enteral nutrition formula for patients with abdominal trauma is within the corresponding standard range of fat content, the corresponding postoperative rehabilitation effect assessment value is set to 1. When the fat content of the early enteral nutrition formula for patients with abdominal trauma is outside the corresponding standard range of fat content, the difference between the fat content parameter of the abdominal trauma patient and the upper limit of the corresponding standard range of fat content is calculated to determine the first reference difference; the difference between the fat content parameter of the abdominal trauma patient and the lower limit of the corresponding standard range of fat content is calculated to determine the second reference difference; the minimum value between the first reference difference and the second reference difference is negatively correlated to determine the corresponding postoperative rehabilitation effect assessment value for the abdominal trauma patient.

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