Opto-electromagnetic field transparent skull window integrated with vertical multi-channel extracellular electrodes and methods of making

By setting a three-dimensional structure with the wire layer perpendicular to the insulation layer and double-layer insulation encapsulation on the transparent cranial window, the problems of traditional transparent cranial windows being unable to record neuronal action potentials and optical occlusion are solved, realizing multimodal neural monitoring with high light transmittance and high conductivity, and supporting brain-computer interface research.

CN122398320APending Publication Date: 2026-07-17INST OF SEMICONDUCTORS - CHINESE ACAD OF SCI

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF SEMICONDUCTORS - CHINESE ACAD OF SCI
Filing Date
2026-06-11
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Traditional transparent cranial windows with integrated electrodes can only record local field potential signals and cannot record neuronal action potentials. Furthermore, they cause severe optical obstruction, which affects neuronal observation and optical imaging.

Method used

A three-dimensional structure with the wire layer perpendicular to the first insulating layer and the conductive layer is adopted. Combined with the double-layer insulating encapsulation and adhesive layer design, a vertical multi-channel extracellular electrode is formed, which reduces the projection area of ​​the opaque material in the optical imaging direction, achieves high light transmittance and high conductivity, and enables simultaneous electrophysiological recording and optical imaging.

Benefits of technology

It enables extracellular recording of deep cortical neurons, maintains high light transmittance, reduces electrode interface impedance, and ensures long-term stable photoelectric dual-modal synchronous monitoring, supporting brain-computer interface research such as neural circuit analysis and brain function localization.

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Abstract

本公开提供了一种集成垂直多通道胞外电极的光电磁场透明颅窗和制备方法,属于脑机接口技术领域。该颅窗包括:第一绝缘层,设有多个第一接触点暴露孔;导电层,设置于第一绝缘层上,导电层包括多个第一接触点;以及导线层,导线层与第一绝缘层和导电层垂直,以降低导电层在光电磁场颅窗上的垂直投影面积;其中,导线层包括多个第二接触点,每个第二接触点通过每个第一接触点暴露孔与每个第一接触点连接。
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