Bletilla striata gum submicron particles, and preparation method and application thereof
By using the Pickering emulsion template method and interfacial crosslinking technology, submicron particles of Bletilla striata gum were prepared, which solved the problems of poor permeability and safety concerns of Bletilla striata gum, and achieved efficient ultraviolet shielding and antioxidant effects, significantly reduced photodamage, and promoted skin barrier repair.
Patent Information
- Application Number
- CN202610571136.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Filing Date
- 2026-04-28
- Publication Date
- 2026-07-17
AI Technical Summary
When Bletilla striata gum is applied directly, it has poor permeability and low bioavailability. Traditional methods for preparing nanoparticles involve chemical cross-linking agents, which pose safety risks.
Using the Pickering emulsion template method and interfacial crosslinking technology, amphiphilic modified Bletilla striata gum nanocrystals and plant flavonoids were used as natural crosslinking agents to prepare Bletilla striata gum submicron particles, forming particles with a core-shell structure. Through oxidative crosslinking at the interface, a robust armor layer was formed.
It enhances the mechanical strength and colloidal stability of the particles, and integrates the barrier repair properties of Bletilla striata gum matrix, the physical light scattering ability of nanocrystalline shell and the chemical UV absorption/antioxidant activity of plant flavonoids into a single particle. It exhibits excellent in vitro function, with a shielding rate of up to 92.5% and 85.3% against UVB and UVA, respectively, and a DPPH free radical scavenging rate of 78.5%. It also significantly reduces photodamage and promotes barrier repair at the cellular and in vivo levels.
Smart Images
Figure CN122398699A_ABST