A rare ginsenoside self-assembled nanoparticle and a preparation method and application thereof
The method of preparing rare ginsenoside self-assembled nanoparticles solves the problems of efficient enrichment and safety of rare ginsenosides, achieving high drug loading and high bioavailability, suitable for large-scale production, and with significant anti-aging effects.
CN122398733APending Publication Date: 2026-07-17SHANGHAI KEDILIAN TECH CO LTD
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SHANGHAI KEDILIAN TECH CO LTD
- Filing Date
- 2026-04-29
- Publication Date
- 2026-07-17
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Figure CN122398733A_ABST
Abstract
本申请公开了一种稀有人参皂苷自组装纳米粒及其制备方法与应用，本申请以人参组培不定根为原料，先经分步水提获得含天然多糖、肽类稳定剂的水提液，再对水提残渣进行醇提得到富集稀有人参皂苷的醇提液；采用改良纳米沉淀法，将醇提液定量滴加水提液，利用稀有人参皂苷自身两亲性结构自发形成无载体核‑壳结构纳米粒，水提液中天然成分同步吸附形成水化膜稳定体系。所制备的纳米粒中稀有人参皂苷占总皂苷质量百分比≥50%，粒径100‑200nm。本申请无需引入任何外源载体和合成稳定剂，安全性高，制备工艺简单可控、能耗低，易于工业化生产；能够显著提高稀有人参皂苷的肠道吸收效率，通过多靶点发挥显著抗衰老功效，可广泛应用于各类抗衰老食品和保健品的开发。
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