A standardized processing method of salted radix astragali

By controlling the amount of water added, the soaking time, and the frying temperature and time in the salt-processing of Astragalus complanatus, and combining it with a multi-index quality evaluation system, the problem of unstable quality caused by unclear parameters in the existing technology has been solved, and the standardized production and efficacy improvement of salt-processed Astragalus complanatus have been achieved.

CN122398883APending Publication Date: 2026-07-17NORTHWEST A & F UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NORTHWEST A & F UNIV
Filing Date
2026-06-17
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

The existing salt-processing technique for Astragalus complanatus lacks quantitative parameters, resulting in strong operational subjectivity, poor quality stability, and a lack of a unified quality evaluation system, which affects the consistency of efficacy.

Method used

By controlling the amount of water added, the soaking time, and the frying temperature and time, a multi-index comprehensive quality evaluation system with Astragalus complanatus glycosides, alcohol-soluble extracts, and water extracts as the core was established. The weights were calculated using the CRITIC method, and the processing technology was optimized by combining the Box-Behnken response surface methodology to achieve standardization and controllability of the process.

Benefits of technology

This method enables quantitative control over the salt-processing of Astragalus complanatus, improving the stability and consistency of drug quality, reducing waste of medicinal materials due to operational differences, and making it suitable for industrial production.

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Abstract

本发明属于中药炮制技术领域,具体涉及一种盐炙沙苑子的标准化炮制方法。包括以下步骤:将沙苑子与盐水混合,加水后进行闷润2h~4h;所述盐水中,NaCl与水的质量体积比为1g:15~25mL,沙苑子与NaCl的质量比为50:1~1.01;在110℃~130℃下炒制15min~25min后,冷却,得到盐炙沙苑子。本发明实现炮制工艺量化控制,明确了盐炙沙苑子加水用量、闷润时间、炒制温度、炒制时间的精准参数,替代了传统经验化操作,消除了人为操作差异,解决了现有工艺“参数模糊、主观性强”的核心问题,使生产过程可重复、可控制。
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