A process for the production of sodium sarcosinate

By employing a continuous flow reaction process and precise parameter control, the problems of insufficient safety and poor controllability in sodium sarcosinate production have been solved, achieving efficient and stable sodium sarcosinate production suitable for large-scale industrialization.

CN122404170APending Publication Date: 2026-07-17
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Patent Information

Application Number
CN202610538268.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Filing Date
2026-04-22
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing sodium sarcosinate production processes suffer from insufficient safety, poor controllability, high raw material risks, and difficulty in large-scale, efficient production.

Method used

A three-stage series falling film reactor and a microchannel reactor are used for continuous flow reaction. Combined with a distributed control system and a safety instrument system, the cyanation and amination reactions are continuous and precisely controlled. Risks are reduced by using low-concentration raw materials and safety interlocking measures. In the hydrolysis step, alkali solution is added dropwise to buffer the exothermic reaction.

Benefits of technology

It has achieved efficient, safe and stable production of sodium sarcosinate, with a yield consistently above 96% and high batch consistency, making it suitable for large-scale industrial applications.

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Abstract

本发明属于化工合成技术领域,具体涉及一种肌氨酸钠的生产工艺方法。本发明通过采用三级串联降膜反应器和微通道反应器,将高风险放热反应改为连续流过程,系统持液量少、比表面积大,能即时移除反应热,从根本上抑制热累积,避免温度压力失控。结合精确的pH控制与低温操作,有效抑制了副反应。连续化平推流与DCS控制保障了物料配比与工艺参数稳定,强化了传质传热;水解阶段通过向碱液中滴加中间体,利用碱液热容缓冲放热,避免了喷料风险,使肌氨酸钠收率稳定在96%以上,产品浓度与纯度指标可靠,批次一致性好。此外,采用低浓度原料降低了储运风险,并设置独立的SIS、GDS及完备应急设施,构成多层防护,显著提升了装置应对异常工况的可靠性。
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