Method for efficiently preparing antioxidant active bovine bone collagen peptide and application thereof
By optimizing the enzymatic hydrolysis parameters through single-enzyme hydrolysis and response surface methodology, the problems of low purity, high energy consumption, and weak antioxidant activity in the traditional preparation of bovine bone collagen peptides have been solved, enabling efficient and green large-scale production. The product has strong antioxidant activity and is suitable for functional foods, health products, and cosmetics.
CN122404535APending Publication Date: 2026-07-17JILIN UNIVERSITY
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- JILIN UNIVERSITY
- Filing Date
- 2026-04-24
- Publication Date
- 2026-07-17
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Figure CN122404535A_ABST
Abstract
本发明属于生物活性肽领域，针对农畜产品加工中牛骨资源浪费与传统胶原肽制备工艺缺陷，提供一种高效制备具抗氧化活性牛骨胶原蛋白肽的方法及其应用。以预处理牛骨粉为原料，采用风味蛋白酶单酶酶解工艺，经精准控温酶解、灭酶、离心与冷冻干燥制得高活性牛骨胶原肽。该肽经结构表征显示保留Ⅰ型胶原蛋白三股螺旋结构与活性官能团，含17种氨基酸，肽段集中于2至10个氨基酸残基且含多种生物活性肽。体外抗氧化检测表明其ABTS自由基清除率呈浓度依赖性增强，10 mg / mL时达62.03%，ORAC值为0.193517 M TE / g，具备优异抗氧化活性。本工艺简化高效、能耗低，可实现牛骨高值化利用，契合扶农助农理念，为功能性食品创新开发与品类拓展提供优质原料与技术支撑。
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