A hydrophilic recombinant human hair keratin and a biosynthetic method thereof
By splicing hydrophilic recombinant human collagen genes using genetic engineering technology, the problems of dissolution difficulties in natural keratin extraction and the introduction of harmful substances through chemical modification have been solved, resulting in high-purity, batch-consistent hydrophilic recombinant human hair keratin suitable for tissue repair, hemostatic materials, and cosmetic additives.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- JINGGANGSHAN UNIVERSITY
- Filing Date
- 2026-06-11
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies for extracting natural keratin suffer from problems such as difficulty in dissolving, inconsistent product quality, water insolubility limiting application, and the introduction of exogenous chemical components through chemical modification, making it difficult to meet the safety and stability requirements of the biopharmaceutical field.
Using genetic engineering technology, the hydrophilic recombinant human collagen gene is spliced with the human hair keratin gene to construct hydrophilic recombinant human hair keratin. The product is then fermented and purified using genetically engineered bacteria, avoiding the use of strong acids, strong alkalis or organic solvents, to ensure high purity and batch consistency.
It achieves high water solubility, good biocompatibility and bioactivity of hydrophilic recombinant human hair keratin, and solves the problems of dissolution difficulties and the introduction of harmful substances by chemical modification in traditional extraction methods. The product has high purity, accurate molecular weight and excellent batch-to-batch consistency, and is suitable for tissue repair, hemostatic materials and cosmetic additives.
Smart Images
Figure CN122404575A_ABST