Compound guanidine acetic acid feed nutrient additive and application thereof

Abstract

The application discloses a kind of composite guanidine group acetic acid feed nutrient additives and application, composite guanidine group acetic acid feed nutrient additives are according to dry base mass fraction, comprising the following components are made into composite granules by granulation processing: guanidine group acetic acid trace element complex: 30~70 parts;Methionine source: 20~60 parts;Carrier and binder: 5~25 parts;Wherein, the guanidine group acetic acid trace element complex is the chelation product of guanidine group acetic acid and trace element;The methionine source is selected from at least one of methionine, methionine salt, methionine hydroxyl analogue, methionine hydroxyl analogue calcium salt.This application integrates guanidine group acetic acid trace element complex, methionine and / or its hydroxyl analogue in a uniform solid particle, not only synergistic between components, and physical property uniform stable, convenient to use, can comprehensively improve the growth performance of animal, feed conversion rate and health condition.

Description

Technical Field

[0001] This invention relates to the field of feed additive technology, specifically to a compound guanidinoacetic acid feed nutrient additive and its application. Background Technology

[0002] In modern intensive livestock production, the precise supplementation of specific nutrients through feed additives is a core means to improve animal growth performance, feed conversion rate, carcass quality, and reduce breeding costs. Among them, guanidinoacetic acid, essential amino acids, and trace minerals are three key feed additives that have attracted much attention.

[0003] Guanidinoacetic acid (GAA) is a direct precursor for creatine synthesis in animals. The creatine-phosphocreatine system is central to the rapid energy supply of muscles and other tissues, playing a crucial role in maintaining energy homeostasis and promoting muscle development. Adding exogenous guanidinoacetic acid to the diet can effectively increase the body's phosphocreatine reserves, directing more energy towards muscle synthesis rather than fat deposition, ultimately improving daily weight gain and carcass lean meat percentage. Meanwhile, trace elements such as copper, iron, zinc, manganese, and chromium are also deeply involved in energy metabolism, protein synthesis, enzyme system activation, and immune function regulation in animals. Existing technologies have developed trace element complexes using guanidinoacetic acid as a ligand. These products chelate trace elements with guanidinoacetic acid ligands through chemical bonds to form stable complexes. However, the formulation design of these products still focuses on "energy metabolism regulation" and "mineral supplementation," failing to effectively integrate with another core limiting factor for animal growth—exogenous essential amino acids absorbed through the intestines. Its product functions have clear boundaries, and it is impossible to solve the problem of insufficient amino acid supply or imbalance in ratio at the same time in a single additive. Summary of the Invention

[0004] The problem to be solved by this invention is to provide a compound guanidinoacetic acid feed nutrient additive and its application, which integrates guanidinoacetic acid trace element complex, methionine and / or its hydroxy analogues into a uniform solid particle. Not only do the components have synergistic effects, but the physical properties are also uniform and stable, and it is easy to use. It can comprehensively improve the growth performance, feed conversion rate and health status of animals.

[0005] The technical solution provided by this invention to solve the above problems is: a compound guanidinoacetic acid feed nutrient additive, comprising, by dry basis mass parts, the following components processed into compound granules: Guanidinoacetic acid trace element complex: 30-70 parts; Methionine source: 20-60 parts; Carrier and adhesive: 5-25 parts; The guanidinoacetic acid trace element complex is a chelation product of guanidinoacetic acid and trace elements; the methionine source is selected from at least one of methionine, methionine salt, methionine hydroxy analog, and methionine hydroxy analog calcium salt.

[0006] Preferably, the trace element is at least one of chromium, iron, zinc, and copper.

[0007] Preferably, the methionine source is a mixture of methionine and methionine hydroxy analogs, with a mass ratio of 1:0.6~1.5.

[0008] Preferably, the carrier and adhesive are selected from at least one of diatomaceous earth, zeolite powder, bentonite, corn starch, dextrin, and sodium carboxymethyl cellulose.

[0009] Preferably, the particle size range of the composite particles is 90~900μm.

[0010] Preferably, the preparation method of the feed nutrient additive includes the following steps: S1. Prepare guanidinoacetic acid trace element complex, dry and pulverize it for later use; S2. Heat the liquid methionine hydroxy analogue of the formula to 40~80℃ to reduce its viscosity, and then spray it evenly onto the first batch of carriers to obtain premix A. S3. Mix the formulated amount of solid methionine crystals, the guanidinoacetic acid trace element complex from step (1), and the second batch of carrier to obtain premix B; S4. Place premix A and premix B together into the granulation equipment, spray a small amount of water or binder solution while stirring, and perform wet granulation to obtain wet granules. S5. Dry the wet granules in a fluidized bed at 50~70℃, controlling the moisture content to ≤5%, to obtain the compound guanidinoacetic acid feed nutrient additive.

[0011] Preferably, the method for preparing the guanidinoacetic acid trace element complex in S1 includes the following steps: S1.1 Add water and animal trace element source to the reaction vessel, start stirring to fully disperse the materials and obtain a dispersion; the animal trace element source is selected from one or more of sulfates, chlorides, carbonates, oxides, basic salts or their crystalline hydrates containing chromium, iron, zinc or copper. S1.2. Then, guanidinoacetic acid is added to the dispersion, and the amount added is controlled according to the molar ratio of guanidinoacetic acid to metal ions in the trace element source of 1.5~3.8:1; the pH of the reaction solution is adjusted to a weakly alkaline range of 7.5~11.0 with an alkaline regulator; the chelation reaction is carried out by continuous stirring under constant temperature conditions of 40℃~80℃ for 0.5~2 hours. S1.3 After the reaction endpoint is reached, the system temperature is lowered to 10℃~40℃, and the product crystals are allowed to fully separate by standing or stirring slowly. Then, the crystal slurry is separated into solid and liquid phases, and the solid phase product is collected. After washing to remove surface impurities, the solid phase product is dried, then pulverized and sieved to obtain powdered guanidinoacetic acid trace element complex for later use.

[0012] The present invention also discloses the application of the compound guanidinoacetic acid feed nutrient additive as described above in feed, wherein the compound guanidinoacetic acid feed nutrient additive is mixed with the base feed using a mixing device to obtain a mixed feed.

[0013] Preferably, the mixing device includes a mixing cylinder and a mixing component, wherein the mixing component is installed on the mixing cylinder for mixing the materials inside the mixing cylinder.

[0014] Preferably, the mixing assembly includes a motor, a main mixing mechanism, and multiple sets of auxiliary mixing mechanisms. The main mixing mechanism includes a rotating shaft and several mixing rods. The motor is mounted on the upper end of the mixing cylinder, and the rotating shaft is connected to the motor for transmission. The mixing rods are evenly distributed on the rotating shaft. The auxiliary mixing mechanisms include a movable rod, a spring, a roller, a drive block, and several mixing plates. The movable rod has an axial mounting hole that mates with the mixing rod. One end of the spring is fixedly connected to the bottom of the mounting hole, and the other end is fixedly connected to the mixing rod. The roller is rotatably mounted on the end of the movable rod away from the mixing rod. The drive block is mounted on the inner wall of the mixing cylinder. The inner surface of the drive block mates with the roller. The inner surface of the drive block is an outwardly convex arc-shaped convex surface. The two sides of the arc-shaped convex surface extend upward to form an inwardly concave first arc-shaped side surface and a second arc-shaped side surface, respectively. The arc-shaped convex surface and the first and second arc-shaped side surfaces are smoothly connected. The mixing plates are disposed on the outer circumferential surface of the movable rod.

[0015] Compared with the prior art, the advantages of the present invention are: the present invention integrates guanidinoacetic acid trace element complex, methionine and / or its hydroxy analogues into a uniform solid particle, which not only has synergistic effect between components, but also has uniform and stable physical properties, is convenient to use, and can comprehensively improve the growth performance, feed conversion rate and health status of animals. Attached Figure Description

[0016] The accompanying drawings, which are provided to further illustrate the invention and constitute a part of this invention, are illustrative embodiments of the invention and their descriptions are used to explain the invention and do not constitute an undue limitation of the invention.

[0017] Figure 1 This is a flowchart of the preparation method of the feed nutrient additive of the present invention; Figure 2This is a flowchart of the method for preparing the guanidinoacetic acid trace element complex of the present invention; Figure 3 This is a schematic diagram of the mixing device of the present invention; Figure 4 This is a front sectional view of the mixing device of the present invention; Figure 5 This is a top sectional view of the mixing apparatus of the present invention; Figure 6 This is a cross-sectional view of the mixing rod and the movable rod of the present invention; Figure 7 yes Figure 6 Enlarged view of point A in the middle; Figure 8 yes Figure 6 Enlarged view of point B in the middle; Figure 9 yes Figure 8 Enlarged view of point C in the middle; Figure 10 This is a schematic diagram of the mixing rod of the mixing device of the present invention.

[0018] Figure labels: 1. Motor; 2. Adjusting handle; 3. Lead screw; 4. Movable cavity; 5. Drive block; 6. Limit block; 7. Roller; 8. Movable rod; 9. Mixing plate; 10. Mixing rod; 11. Rotating shaft; 12. Mixing cylinder; 13. First arc-shaped side; 14. Arc-shaped convex surface; 15. Second arc-shaped side; 16. Spring; 17. Mounting hole; 18. Mounting ring one; 19. Corrugated hose; 20. Top rod; 21. Piston head; 22. Piston cavity; 23. Air outlet pipe; 24. Fixing rod; 25. One-way valve one; 26. Air inlet pipe; 27. Air outlet; 28. One-way valve two; 29. ​​Sealing ring; 30. Annular air groove; 31. Mounting ring three; 32. Mounting ring two. Detailed Implementation

[0019] The following will describe in detail the implementation of the present invention with reference to the accompanying drawings and embodiments, so that the process of how the present invention uses technical means to solve technical problems and achieve technical effects can be fully understood and implemented accordingly.

[0020] In the description of this invention, it should be noted that the directional terms such as "center", "lateral", "longitudinal", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", and "counterclockwise" indicate the orientation and positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. They should not be construed as limiting the specific protection scope of this invention.

[0021] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features. Thus, the use of "first" and "second" to define a feature may explicitly or implicitly include one or more of that feature, and in the description of this invention, "a number" means two or more, unless otherwise explicitly specified.

[0022] In this invention, unless otherwise explicitly specified and limited, the terms "assembly," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can also refer to a mechanical connection; they can refer to a direct connection or a connection through an intermediate medium; or they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0023] It should be understood that, when used in this specification and the appended claims, the terms "comprising" and "including" indicate the presence of the described features, integrals, steps, operations, elements and / or components, but do not exclude the presence or addition of one or more other features, integrals, steps, operations, elements, components and / or collections thereof.

[0024] It should also be understood that the terminology used in this specification of embodiments of the invention is for the purpose of describing particular embodiments only and is not intended to limit the embodiments of the invention. As used in this specification of embodiments of the invention and the appended claims, the singular forms “a,” “an,” and “the” are intended to include the plural forms unless the context clearly indicates otherwise. Example 1

[0025] This embodiment discloses a compound guanidinoacetic acid feed nutrient additive, which, by dry basis mass parts, comprises the following components processed into compound granules: Guanidinoacetic acid trace element complex: 30-70 parts; Methionine source: 20-60 parts; Carrier and adhesive: 5-25 parts; The guanidinoacetic acid trace element complex is a chelation product of guanidinoacetic acid and trace elements; the methionine source is selected from at least one of methionine, methionine salt, methionine hydroxy analog, and methionine hydroxy analog calcium salt.

[0026] The trace element is at least one of chromium, iron, zinc, and copper.

[0027] The methionine source is a mixture of methionine and methionine hydroxy analogs, with a mass ratio of 1:0.6~1.5.

[0028] The carrier and adhesive are selected from at least one of diatomaceous earth, zeolite powder, bentonite, corn starch, dextrin, and sodium carboxymethyl cellulose.

[0029] The particle size range of the composite particles is 90~900μm.

[0030] The above scheme has the following advantages: 1. Three-in-one efficacy, synergistic effect: This invention integrates "guanidinoacetic acid", "highly absorbed trace mineral elements" and "methionine source" into a single granule product, achieving triple nutritional enhancement of "energy substrate for promoting muscle growth (creatine precursor) + core component for promoting body protein synthesis (methionine) + key cofactor of enzyme system (trace elements)", which can achieve weight gain and feed conversion effects far exceeding those of using them alone or in combination.

[0031] 2. Stable physical properties and high utilization: The composite pellets prepared by this invention have uniform composition, are dust-free, and have good flowability, which can effectively prevent product grading during feed processing and transportation, ensuring the nutritional uniformity of each feed serving. At the same time, the pellet form also helps to reduce picky eating by animals and slow dissolution in the digestive tract, improving the continuous nutritional supply effect.

[0032] 3. High safety and environmental friendliness: The trace element portion of this invention exists in the form of guanidinoacetic acid complexes, rather than inorganic salts. This not only provides an absorption channel for trace elements that is not blocked by anti-nutritional factors such as phytic acid in feed, greatly improving the bioavailability of trace elements, but also significantly reduces the amount of inorganic trace elements added and the amount of fecal emissions, reducing the environmental burden. The raw materials used in the product do not contain harmful substances such as nitrates and perchlorates, and meet feed hygiene standards.

[0033] 4. Simplify breeding operations and reduce costs: Farmers do not need to purchase, weigh, and mix multiple single products such as guanidinoacetic acid, methionine, and organic trace elements separately. They only need to add one standardized compound product, which reduces the difficulty of inventory management and human operation errors, and lowers the overall cost of use. Example 2

[0034] This embodiment discloses a method for preparing a feed nutrient additive as described in Example 1, specifically including the following steps: S1. Prepare guanidinoacetic acid trace element complex, dry and pulverize it for later use; S2. Heat the liquid methionine hydroxy analogue of the formula to 40~80℃ to reduce its viscosity, and then spray it evenly onto the first batch of carriers to obtain premix A. S3. Mix the formulated amount of solid methionine crystals, the guanidinoacetic acid trace element complex from step (1), and the second batch of carrier to obtain premix B; S4. Place premix A and premix B together into the granulation equipment, spray a small amount of water or binder solution while stirring, and perform wet granulation to obtain wet granules. S5. Dry the wet granules in a fluidized bed at 50~70℃, controlling the moisture content to ≤5%, to obtain the compound guanidinoacetic acid feed nutrient additive.

[0035] The method for preparing the guanidinoacetic acid trace element complex in S1 includes the following steps: S1.1 Add water and animal trace element source to the reaction vessel, start stirring to fully disperse the materials and obtain a dispersion; the animal trace element source is selected from one or more of sulfates, chlorides, carbonates, oxides, basic salts or their crystalline hydrates containing chromium, iron, zinc or copper. S1.2. Then, guanidinoacetic acid is added to the dispersion, and the amount added is controlled according to the molar ratio of guanidinoacetic acid to metal ions in the trace element source of 1.5~3.8:1; the pH of the reaction solution is adjusted to a weakly alkaline range of 7.5~11.0 with an alkaline regulator; the chelation reaction is carried out by continuous stirring under constant temperature conditions of 40℃~80℃ for 0.5~2 hours. S1.3 After the reaction endpoint is reached, the system temperature is lowered to 10℃~40℃, and the product crystals are allowed to fully separate by standing or stirring slowly. Then, the crystal slurry is separated into solid and liquid phases, and the solid phase product is collected. After washing to remove surface impurities, the solid phase product is dried, then pulverized and sieved to obtain powdered guanidinoacetic acid trace element complex for later use. Example 3

[0036] This embodiment discloses the application of the compound guanidinoacetic acid feed nutrient additive as described in Example 1 in feed. The compound guanidinoacetic acid feed nutrient additive is mixed with the base feed using a mixing device to obtain a mixed feed. Example 4

[0037] This embodiment discloses a mixing device, which is applied in embodiment 3. Specifically, the mixing device includes a mixing cylinder 12 and a mixing component. The mixing component is installed on the mixing cylinder 12 for mixing the materials in the mixing cylinder 12.

[0038] The mixing assembly includes a motor 1, a main mixing mechanism, and multiple sets of auxiliary mixing mechanisms. The main mixing mechanism includes a rotating shaft 11 and several mixing rods 10. The motor 1 is mounted on the upper end of the mixing cylinder 12, and the rotating shaft 11 is connected to the motor 1 for transmission. The mixing rods 10 are evenly distributed on the rotating shaft 11. The auxiliary mixing mechanisms include a movable rod 8, a spring 16, a roller 7, a drive block 5, and several mixing plates 9. The movable rod 8 is provided with an axial mounting hole 17 that mates with the mixing rod 10. One end of the spring 16 is fixedly connected to the bottom of the mounting hole 17, and the other end is connected to the mixing rod 10. The material rod 10 is fixedly connected, and the roller 7 is rotatably mounted on the end of the movable rod 8 away from the mixing rod 10. The driving block 5 is mounted on the inner wall of the mixing cylinder 12. The inner surface of the driving block 5 cooperates with the roller 7. The inner surface of the driving block 5 is an outwardly convex arc-shaped convex surface 14. The two sides of the arc-shaped convex surface 14 extend upward to form an inwardly concave first arc-shaped side surface 13 and a second arc-shaped side surface 15, respectively. The arc-shaped convex surface 14 and the first arc-shaped side surface 13 and the second arc-shaped side surface 15 are all smoothly connected. The mixing plate 9 is disposed on the outer circumferential surface of the movable rod 8.

[0039] The auxiliary mixing mechanism further includes a sealing assembly and a purging assembly. The sealing assembly includes a first mounting ring 18, a second mounting ring, and a retractable corrugated hose 19. The first mounting ring 18 is disposed on the wall of the mounting hole 17, and the second mounting ring is disposed on the outer circumferential surface of the mixing rod 10. The corrugated hose 19 is fitted onto the mixing rod 10, with one end connected to the first mounting ring 18 and the other end connected to the second mounting ring. A third mounting ring is also disposed on the wall of the mounting hole 17, and an annular mounting groove is disposed on the inner wall of the third mounting ring, with a sealing ring 29 disposed in the annular mounting groove. The purging assembly includes a push rod 20, a piston head 21, and a fixing rod 24. One end of the push rod 20 is fixedly connected to one end of the mixing rod 10, and the other end is fixedly connected to the piston head 21. One end of the fixing rod 24 is fixedly connected to the bottom of the mounting hole 17. The fixed rod 24 is provided with an axial piston chamber 22. The piston head 21 cooperates with the piston chamber 22. The bottom of the piston chamber 22 is provided with an inlet pipe 26 and an outlet pipe 23 communicating with it. A one-way valve 25 is provided in the inlet pipe 26. The one-way valve 25 is used to control the one-way flow of gas from the outside of the piston chamber 22 to the inside of the piston chamber 22. A one-way valve 28 is provided in the outlet pipe 23. The one-way valve 28 is used to control the one-way flow of gas from the inside of the piston chamber 22 to the outside of the piston chamber 22. An annular air groove 30 is provided on the mounting ring 3. The end of the outlet pipe 23 away from the piston chamber 22 extends to the mounting ring 3 and communicates with the annular air groove 30. A plurality of air outlet holes 27 are provided on the annular air groove 30. The air outlet holes 27 are inclined and point away from the side of the mounting ring 2.

[0040] The inner wall of the mixing cylinder 12 is provided with several movable cavities 4 for the drive block 5 to move up and down. The drive block 5 is provided with a threaded hole, and a lead screw 3 is installed in the threaded hole. The inner wall of the mixing cylinder 12 is provided with a limiting block 6 for limiting the lead screw 3. The lead screw 3 is rotatably connected to the limiting block 6. One end of the lead screw 3 passes through the top cover of the mixing cylinder 12 and extends out of the mixing cylinder 12. An adjusting handle 2 is provided on the top of the lead screw 3.

[0041] In the above scheme, after the motor is started, it drives the rotating shaft and mixing rod to rotate, performing primary mixing of the material. During the normal mixing stage, the drive block can be raised along the movable cavity by rotating the adjustment handle, causing the lead screw to completely disengage the drive block from the rollers on the secondary mixing mechanism in the axial direction. At this time, the movable rod remains in its initial extended position under the action of the spring, only revolving circumferentially with the rotating shaft, without generating radial mixing of the material. The device is in normal working mode, which helps to reduce energy consumption and extend the service life of components such as sealing components and springs. When the process requires enhanced mixing effect, the motor is first turned off (when the motor is off, the control shaft drives the rollers to move horizontally to the position where they are disengaged from the drive block). Then, the operator rotates the adjustment handle to lower the drive block driven by the lead screw until the inner surface of the drive block enters the axial travel range of the rollers. Then the motor is turned on again, and as the rotating shaft drives the movable rod to rotate, the rollers begin to roll along the inner surface of the drive block. When the roller rolls to the convex arc-shaped surface on its inner surface, the convex surface pushes the roller and the movable rod radially inward along the mixing rod, compressing the spring. When the roller passes the convex surface and enters the concave first or second arc-shaped side area, the spring force pushes the movable rod outward, ensuring the roller remains in contact with the inner surface of the drive block. Because the arc-shaped convex surface and the arc-shaped side areas are smoothly transitioned, the movable rod can generate a smooth axial reciprocating motion while rotating circumferentially. This reciprocating motion causes radial displacement of the mixing plates on the outer circumference of the movable rod, creating a radial and circumferential composite mixing of the material, significantly improving mixing uniformity. To restore normal mixing, simply turn the handle again to raise the drive block, disengaging the roller from the drive block. During this reciprocating motion, sealing and purging protection work simultaneously. As the movable rod extends and retracts relative to the mixing rod, the corrugated hose extends and retracts accordingly, always covering the connection gap between the two to prevent material from entering the mounting hole; the sealing ring on the mounting ring provides further sealing. Simultaneously, the movement of the movable rod drives the piston action of the purging assembly: when the movable rod extends, the piston chamber volume increases, and external gas is drawn in through one-way valve one; when the movable rod retracts, the piston chamber volume decreases, and the gas inside the chamber is forced out through one-way valve two, enters the annular air groove through the air pipe, and finally is sprayed obliquely from multiple air outlets to the outside of the sealing ring, forming an air curtain that blows away material particles attempting to invade, achieving self-cleaning and ensuring the reliability of long-term operation.

[0042] This device achieves multi-dimensional composite mixing of materials through the coordinated operation of the main mixing mechanism and the auxiliary mixing mechanism. While the rotating shaft drives the mixing rod to perform circumferential rotation for main mixing, the drive block, rollers, and springs work together to force the movable rod and its mixing plate to reciprocate radially. This composite motion effectively disrupts the regular flow field that easily forms under single rotation, significantly reducing dead zones and ensuring that the material is fully agitated and convected in the axial, radial, and circumferential directions, greatly improving mixing uniformity and efficiency.

[0043] The adjustable drive block design provides the device with flexible operating modes and effectively extends the service life of key components. Operators can easily disengage or engage the drive block with the rollers by adjusting the handle according to actual process requirements. Under normal mixing conditions, the two are disengaged, the secondary mixing mechanism does not perform radial vibration, and the device operates smoothly with low energy consumption, while avoiding continuous mechanical wear of components such as springs, rollers, and sealing assemblies. The drive block is only engaged when a stronger mixing effect is needed, thus achieving an optimal balance between enhanced functionality and component lifespan protection.

[0044] The organic integration of the sealing and automatic purging systems fundamentally solves the dynamic sealing problem of rotating telescopic components under powder or particle conditions. The corrugated hose, acting as the first dynamic isolation barrier, deforms with the extension and retraction of the movable rod, effectively covering the movement gap at all times. Furthermore, this solution cleverly utilizes the reciprocating motion of the movable rod itself as a power source to drive the piston assembly, continuously spraying airflow at an angle from multiple air outlets in the annular air groove towards the outside of the sealing ring. This self-supplying air curtain purging eliminates the need for additional air sources and control systems, forming an active defense at the sealing area, blowing away any attempting intrusive material particles in real time. This achieves excellent self-cleaning functionality, significantly reducing the risk of seal failure and mechanical jamming caused by material intrusion, and ensuring the long-term reliability and maintenance-free operation of the device.

[0045] The above description only illustrates the preferred embodiments of the present invention and should not be construed as limiting the scope of the claims. The present invention is not limited to the above embodiments, and variations in its specific structure are permitted. All modifications made within the scope of the independent claims of this invention are also within the scope of protection of this invention.

Claims

1. A compound guanidinoacetic acid feed additive, characterized in that, Based on dry weight, the following components are granulated into composite particles: Guanidinoacetic acid trace element complex: 30-70 parts; Methionine source: 20-60 parts; Carrier and adhesive: 5-25 parts; The guanidinoacetic acid trace element complex is a chelation product of guanidinoacetic acid and trace elements; the methionine source is selected from at least one of methionine, methionine salt, methionine hydroxy analog, and methionine hydroxy analog calcium salt.

2. The compound guanidinoacetic acid feed additive according to claim 1, characterized in that, The trace element is at least one of chromium, iron, zinc, and copper.

3. The compound guanidinoacetic acid feed additive according to claim 1, characterized in that, The methionine source is a mixture of methionine and methionine hydroxy analogs, with a mass ratio of 1:0.6~1.

5.

4. The compound guanidinoacetic acid feed additive according to claim 1, characterized in that, The carrier and binder are selected from at least one of diatomaceous earth, zeolite powder, bentonite, corn starch, dextrin, and sodium carboxymethyl cellulose.

5. The compound guanidinoacetic acid feed additive according to claim 1, characterized in that, The particle size range of the composite particles is 90~900μm.

6. The compound guanidinoacetic acid feed additive according to claim 1, characterized in that, The preparation method of the feed nutrient additive includes the following steps: S1. Prepare guanidinoacetic acid trace element complex, dry and pulverize it for later use; S2. Heat the liquid methionine hydroxy analogue of the formula to 40~80℃ to reduce its viscosity, and then spray it evenly onto the first batch of carriers to obtain premix A. S3. Mix the formulated amount of solid methionine crystals, the guanidinoacetic acid trace element complex from step (1), and the second batch of carrier to obtain premix B; S4. Place premix A and premix B together into the granulation equipment, spray a small amount of water or binder solution while stirring, and perform wet granulation to obtain wet granules. S5. Dry the wet granules in a fluidized bed at 50~70℃, controlling the moisture content to ≤5%, to obtain the compound guanidinoacetic acid feed nutrient additive.

7. The compound guanidinoacetic acid feed additive according to claim 6, characterized in that, The method for preparing the guanidinoacetic acid trace element complex in S1 includes the following steps: S1.1 Add water and animal trace element source to the reaction vessel, start stirring to fully disperse the materials and obtain a dispersion; the animal trace element source is selected from one or more of sulfates, chlorides, carbonates, oxides, basic salts or their crystalline hydrates containing chromium, iron, zinc or copper. S1.

2. Then, guanidinoacetic acid is added to the dispersion, and the amount added is controlled according to the molar ratio of guanidinoacetic acid to metal ions in the trace element source of 1.5~3.8:1; the pH of the reaction solution is adjusted to a weakly alkaline range of 7.5~11.0 with an alkaline regulator; the chelation reaction is carried out by continuous stirring under constant temperature conditions of 40℃~80℃ for 0.5~2 hours. S1.3 After the reaction endpoint is reached, the system temperature is lowered to 10℃~40℃, and the product crystals are allowed to fully separate by standing or stirring slowly. Then, the crystal slurry is separated into solid and liquid phases, and the solid phase product is collected. After washing to remove surface impurities, the solid phase product is dried, then pulverized and sieved to obtain powdered guanidinoacetic acid trace element complex for later use.

8. The application of a compound guanidinoacetic acid feed additive as described in any one of claims 1-7 in feed, characterized in that: The compound guanidinoacetic acid feed nutrient additive is mixed with the base feed using a mixing device to obtain a mixed feed.

9. The application of the compound guanidinoacetic acid feed additive according to claim 8 in feed, characterized in that, The mixing device includes a mixing cylinder and a mixing component, wherein the mixing component is installed on the mixing cylinder for mixing the materials inside the mixing cylinder.

10. The application of the compound guanidinoacetic acid feed additive according to claim 9 in feed, characterized in that, The mixing assembly includes a motor, a main mixing mechanism, and multiple sets of auxiliary mixing mechanisms. The main mixing mechanism includes a rotating shaft and several mixing rods. The motor is mounted on the upper end of the mixing cylinder, and the rotating shaft is connected to the motor for transmission. The mixing rods are evenly distributed on the rotating shaft. The auxiliary mixing mechanisms include a movable rod, a spring, a roller, a drive block, and several mixing plates. The movable rod has an axial mounting hole that mates with the mixing rod. One end of the spring is fixedly connected to the bottom of the mounting hole, and the other end is fixedly connected to the mixing rod. The roller is rotatably mounted on the end of the movable rod away from the mixing rod. The drive block is mounted on the inner wall of the mixing cylinder. The inner surface of the drive block mates with the roller. The inner surface of the drive block is an outwardly convex arc-shaped surface. The two sides of the arc-shaped convex surface extend upward to form an inwardly concave first arc-shaped side surface and a second arc-shaped side surface, respectively. The arc-shaped convex surface and the first and second arc-shaped side surfaces are smoothly connected. The mixing plates are disposed on the outer circumferential surface of the movable rod.

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