Extraction of total flavonoids from papaya and its application

CN122440682APending Publication Date: 2026-07-24GUANGXI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
GUANGXI UNIV
Filing Date
2025-01-24
Publication Date
2026-07-24

AI Technical Summary

Technical Problem

The lack of effective extraction processes for total flavonoids from papaya and their application in promoting lactation in existing technologies has prevented the full realization of its medicinal value.

Method used

The extraction process of total flavonoids from papaya was optimized using response surface methodology. Optimal extraction parameters, including the solid-liquid ratio, ethanol volume fraction, ultrasonic duration, and ultrasonic power, were determined through single-factor experiments and multinomial regression analysis. Component identification was performed using liquid chromatography-mass spectrometry (LC-MS) to derive the optimal extraction process.

Benefits of technology

This study provides an efficient and low-cost extraction process for total flavonoids from papaya, which significantly improves the extraction rate. The results also demonstrate its lactation-promoting effect through a lactation model, providing a research foundation for products that are both food and medicine.

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Abstract

The application discloses a kind of extraction process of papaya total flavone, comprising: step one, the optimum value of each influencing factor is determined by single factor experiment;Step two, with the optimum value of influencing factor as center, and with influencing factor as the independent variable of response surface experiment, with the content of papaya total flavone as response value, polynomial fitting regression is carried out to each independent variable to obtain equation, the optimum process parameter of influencing factor is obtained by response surface analysis of regression equation;Step three, with the optimum process parameter of each influencing factor as extraction parameter, papaya total flavone extraction is carried out.The application combines and applies single factor experiment and response surface method, optimizes the parameter of papaya total flavone extraction process, fills the blank of papaya total flavone extraction process at present, and the papaya total flavone extracted by the process has good lactation-promoting effect, which provides research basis for developing it into a kind of lactation-promoting good medicine of food and medicine.
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