Packaging containing desiccant entrained polymer parts

Abstract

The present disclosure provides a package comprising an enclosure defining an interior space. A desiccant-entrained polymer component is disposed within the interior space comprising an integral composition formed from 35-45 wt% base polymer, 50-60 wt% mineral desiccant, and 2-10 wt% ethylene-vinyl acetate (EVA) channel former. A product in powder form is disposed within the interior space. The desiccant-entrained polymer component scavenges moisture within the package to maintain a desired quality of the product, and complies with one or more of Chinese National Food Safety Standards GB 9685-2016, GB 4806.6-2016, GB 4806.7-2016, GB 4806.1-2016, and GB 31603-2015.

Description

Cross-reference to related applications

[0001] This application claims the benefit of priority to U.S. Provisional Patent Application Serial No. 63 / 547,753, filed November 8, 2023, entitled “PACKAGESCONTAINING DESICCANT ENTRAINED POLYMER COMPONENTS”, pursuant to 35 USC §119(e), the contents of which are incorporated herein by reference in their entirety.

[0002] 1. Field of the Invention This invention generally relates to desiccants encapsulated with plastic formulations. More specifically, this invention relates to the use of such formulations as dehumidifying components adjacent to the product in product packaging.

[0003] 2. Description of related technologies There are many articles that are preferably stored, transported, and / or used in environments where control and / or regulation are necessary. For example, in the field of moisture control, it has been recognized that containers and / or packaging capable of absorbing excess moisture trapped within are desirable. In medical, electronic, and food packaging applications, it may be desirable to control moisture, oxygen, ethylene, and other gaseous substances.

[0004] Conventionally, desiccants, oxygen absorbers, and other surfactants in their original form, such as loose granules contained in pouches or cans, are used within packaging to control the internal environment of the packaging. For many applications, such loosely stored active substances are undesirable. To address this issue, the agents of this application have developed active entrained polymers comprising surfactants, wherein such polymers can be extruded and / or molded into desired forms, such as container liners, stoppers, film sheets, granules, and other such substances. Optionally, such active entrained polymers may include a channel-forming agent, such as polyethylene glycol (PEG), which forms channels between the surface of the entrained polymer and its interior to transport selected materials (e.g., moisture) to the entrained surfactant (e.g., a desiccant to absorb moisture). The entrained polymer can be a two-phase formulation (i.e., comprising a base polymer and an surfactant without a channel-forming agent) or a three-phase formulation (i.e., comprising a base polymer, an surfactant, and a channel-forming agent). The entrained polymers are described, for example, in U.S. Patent Nos. 5,911,937, 6,080,350, 6,124,006, 6,130,263, 6,194,079, 6,214,255, 6,486,231, 7,005,459 and U.S. Patent Publication No. 2016 / 0039955, each of which is incorporated herein by reference as fully illustrated.

[0005] Entrained polymers can be advantageously molded to form components with specific geometries. However, high desiccant loads can make such components brittle. This is because typical desiccant materials are in mineral form, such as silica gel, molecular sieves, and bentonite. The more desiccant, the stronger the moisture absorption capacity, but the more brittle the resulting product. A desiccant load of 60-70% is typical for desiccant-entrained polymers in the form of discs, liners, and films used for product packaging. However, such desiccants often serve only a drying function or may provide a defined cavity for product storage (e.g., desiccant linings in diagnostic test strip vials). Due to the brittleness of high mineral desiccant-loaded components, they are generally unsuitable for actively and physically bonding (e.g., puncturing) other components, as there is a risk of breakage.

[0006] Many countries have established regulations or standards for food quality and integrity. In China, these matters are governed by the Food Safety Law of the People's Republic of China and numerous implementing regulations concerning the production, distribution, recall, and import / export of food in China. These regulations include food packaging standards. For example, GB 9685-2016 specifies a positive list of permitted additives that can be used in the production of food contact materials and articles. GB 4806.1-2016 specifies requirements for food contact materials applicable to food contact additives, including restrictions on the release of materials into food that may be harmful to human health or alter the composition, taste, or odor of food. GB 4806.6-2016 and GB 4806.7-2016 specify rules for the use of resins, resin blends, and other plastics in plastic materials and articles for food contact. GB 31603-2015 specifies extensive regulations and requirements for the production of food contact materials and articles, including production requirements and standards, inspection requirements, material requirements, and other production-related requirements. However, to the applicant's knowledge, no molded desiccant-encased polymer components for food contact applications meet these stringent regulatory requirements.

[0007] Therefore, there is a need for a desiccant-encapsulated polymer that complies with Chinese national food standards for packaging components in contact with food, while also providing a drying effect within an enclosed space. There is also a need for such a desiccant-encapsulated polymer that can maintain its structural integrity when used as a puncture element. Summary of the Invention

[0008] Therefore, in one respect, the disclosed concept relates to a package containing a desiccant-encased polymer component having a suitable composition to comply with all relevant food standards and regulations, while providing sufficient dehumidification and adsorption properties.

[0009] In an optional embodiment, the entire component is made from a formulation comprising 50-60 wt% mineral desiccant, 35-45 wt% base polymer, and 2-10 wt% ethylene vinyl acetate (EVA) channel forming agent. The mineral desiccant is optionally a molecular sieve. The base polymer is optionally polypropylene. The aforementioned desiccant-encapsulated polymer advantageously provides sufficient hygroscopicity for the intended application without making the component too brittle to be used as a puncture element.

[0010] The packaging is optionally a vial, bottle, or cap suitable for use as a container. In an optional embodiment, the desiccant-encapsulating polymer component is a piercing assembly comprising a cutting blade or tip disposed within the packaging. The piercing element is configured to pierce part of the packaging, thereby releasing the product stored within the packaging. For example, the piercing element may pierce the cap to release the product into a container containing liquid, thereby allowing the product to mix into the container. Attached Figure Description

[0011] The invention will be described in conjunction with the following drawings, in which the same reference numerals denote the same elements, and wherein: Figure 1 This is a perspective view of a plug formed by a desiccant entraining polymer, used to illustrate the structure of the entrained polymer.

[0012] Figure 2 It is along Figure 1 The cross section cut by line 2-2.

[0013] Figure 3 It is similar to Figure 2 The cross-section shows a plug formed from another embodiment of a desiccant-entrained polymer.

[0014] Figure 4 This is a schematic diagram of the polymer entrained in the desiccant.

[0015] Figure 5 It is an illustration of optional packaging based on the disclosed concept, before the product is filled into the packaging and without a cap.

[0016] Figure 6 yes Figure 5 The packaging is filled with the product and includes a cap at the opening of the packaging, thus providing a schematic diagram of the sealing position.

[0017] Figure 7 It is placed on the bottle Figure 6 A diagram illustrating the filling and sealing of the packaging.

[0018] Figure 8 yes Figure 7 A schematic diagram of a packaging and dispensing device, showing the product dispensing operation from the packaging. Detailed Implementation

[0019] As used herein, the term "base polymer" refers to a polymer that optionally has a gas permeability of the selected material that is substantially lower than, lower than, or substantially equivalent to the gas permeability of the channel forming agent. For example, in embodiments where the selected material is moisture and the active agent is a desiccant that absorbs or adsorbs water, such permeability would be water vapor permeability. The primary function of the base polymer is to provide the structure for entraining the polymer. Suitable base polymers may include thermoplastic polymers, such as polyolefins like polypropylene and polyethylene, polyisoprene, polybutadiene, polybutene, polysiloxanes, polycarbonates, polyamides, ethylene-vinyl acetate copolymers, ethylene-methacrylate copolymers, poly(vinyl chloride), polystyrene, polyesters, polyanhydrides, polyacrylonitrile, polysulfone, polyacrylates, acrylic acid, polyurethanes and polyacetals, or copolymers or mixtures thereof.

[0020] Referring to such a comparison of the water vapor transmission rates of the base polymer and the channel forming agent, in one embodiment, the water vapor transmission rate of the channel forming agent is at least twice that of the base polymer. In another embodiment, the water vapor transmission rate of the channel forming agent is at least five times that of the base polymer. In another embodiment, the water vapor transmission rate of the channel forming agent is at least ten times that of the base polymer. In yet another embodiment, the water vapor transmission rate of the channel forming agent is at least twenty times that of the base polymer. In yet another embodiment, the water vapor transmission rate of the channel forming agent is at least fifty times that of the base polymer. In yet another embodiment, the water vapor transmission rate of the channel forming agent is at least one hundred times that of the base polymer.

[0021] As used herein, the term "a channel-forming agent" or "multiple channel-forming agents" is defined as a material that is immiscible with a base polymer and has an affinity for transporting gaseous substances at a faster rate than the base polymer. Optionally, when formed by mixing the channel-forming agent with a base polymer, the channel-forming agent is able to form channels through the entrained polymer. Such channels are able to transport selected materials through the entrained polymer at a faster rate than the base polymer alone.

[0022] As used herein, the term “channel” or “interconnected channel” is defined as a pathway formed by a channel-forming agent that penetrates a base polymer and can interconnect with each other.

[0023] As used herein, the term "entrained polymer" is defined as a monolithic material formed together with at least a base polymer, a mineral desiccant, and optionally, an entrained or integrally distributed channel-forming agent. Entrained polymers therefore include both two-phase and three-phase polymers. "Desiccant-entrained polymers" are a type of entrained polymer in which the active agent is in the form of a desiccant, such as a mineral desiccant, for example, mineral particles, such as molecular sieves or silica gel.

[0024] As used herein, the term “mineral desiccant” is defined as a mineral material that: (1) is immiscible with the base polymer and will not melt when mixed with the base polymer and the channel forming agent and heated, i.e., has a melting point higher than that of the base polymer or the channel forming agent; and (2) absorbs, adsorbs or releases selected material with the aim of adsorbing moisture within a desired volume.

[0025] As used herein, the terms “monolithic,” “monolithic structure,” or “monolithic composition” are defined as compositions or materials that are not composed of two or more discrete macroscopic layers or portions. Therefore, “monolithic composition” does not include multilayer complexes.

[0026] As used herein, the term "phase" is defined as a portion or component of a structure or composition that is uniformly distributed throughout to provide its overall properties to the structure or composition.

[0027] As used herein, the term "selected material" is defined as a material that acts upon, interacts with, or reacts with a desiccant and is capable of being transported through channels that entrain polymers. For example, in embodiments using mineral desiccants, the selected material may be moisture or gas that can be absorbed or adsorbed by the mineral desiccant.

[0028] As used herein, the term "triphase" is defined as an integral composition or structure comprising three or more phases (i.e., at least a base polymer, an active agent, and a channel-forming agent). Optionally, a triphase composition or structure may include an additional phase, such as a colorant.

[0029] Figure 1-4An exemplary entrained polymer 10 is shown, which can be used according to various aspects of the disclosed concept. Each entrained polymer 10 includes a base polymer 25, a channel forming agent 35, and a mineral desiccant 30. As shown, the channel forming agent 35 forms interconnecting channels 45 through the entrained polymer 10. At least some of the mineral desiccants 30 are contained within these channels 45, such that the channels 45 communicate between the mineral desiccant 30 and the exterior of the entrained polymer 10 through channel openings 48 formed at the outer surface of the entrained polymer 25. The mineral desiccant 30 can be any of a variety of absorbent, adsorbent, or release materials, such as those described in further detail below. While a channel forming agent, such as 35, is preferred, the invention broadly encompasses entrained polymers that optionally do not contain a channel forming agent.

[0030] Suitable channel forming agents may include ethylene vinyl acetate (EVA), propylene oxide polymeric ester-monobutyl ether (e.g., Polyglykol B01 / 240, produced by CLARIANT), or propylene oxide polymeric ester (e.g., Polyglykol D01 / 240, produced by CLARIANT), or any combination thereof.

[0031] In any embodiment, the polymer 10 is in the form of an injection-molded component. Such an injection-molded component may have a complex three-dimensional geometry. Optionally, the component has a maximum thickness of at least 2 mm, or at least 3 mm, or at least 4 mm, and a width and height each greater than that thickness.

[0032] Figure 4 An embodiment of the entrained polymer 10 according to an optional aspect of the disclosed concept is shown, wherein the mineral desiccant 30 is an absorbent or adsorbent material. Arrows indicate the path of the selected material, such as moisture or gas, from the outside of the entrained polymer 10 through channel 45 to the mineral desiccant particles 30 that absorb or adsorb the selected material.

[0033] Any suitable desiccant can be used for a given application. Typically, physical adsorption desiccants are preferred for many applications. These physical adsorption desiccants may include molecular sieves, silica gel, clay, and starch. Optionally, the molecular sieve is a 3A molecular sieve. Alternatively, the desiccant may be a chemical compound that forms water-containing crystals or a compound that reacts with water to form a new compound. Optionally, in any embodiment, the desiccant is a mineral.

[0034] It is believed that a higher concentration of mineral desiccant in the mixture results in a greater absorption, adsorption, or release capacity (as the case may be) of the final composition. However, excessively high concentrations of mineral desiccant, particularly in the form of mineral particles, can cause the entrained polymer to become brittle once it solidifies. Furthermore, a high mineral loading in the entrained polymer can make the molten mixture of mineral desiccant, base polymer, and channel forming agent more difficult to thermoform, extrude, or injection mold. Therefore, the applicant has found that, when considering the brittleness of mineral-loaded entrained polymers, the mineral loading percentage (by weight) of the entrained polymer should preferably be only the amount absolutely necessary for its active function (e.g., moisture absorption). In one embodiment, the mineral desiccant loading level may range from 20% to 60% by weight, optionally from 30% to 50% by weight, relative to the total weight of the entrained polymer. Optionally, if used, a channel forming agent may be provided in the range of 2% to 10% by weight. Optionally, the base polymer may range from 40% to 80% by weight of the total composition. Optionally, a colorant may be added, for example, at about 2% by weight of the total composition. However, it should be understood that desiccants containing polymers may be free of colorants in order to comply with relevant food storage standards and regulations.

[0035] In some embodiments, the mineral-entrained polymer is a desiccant-entrained polymer. The desiccant-entrained polymer comprises an integral composition formed of a base polymer, a mineral desiccant, and a channel-forming agent. In a preferred embodiment, the channel-forming agent is ethylene vinyl acetate (EVA) to comply with one or more Chinese national food safety standards, including GB 9685-2016, GB 4806.6-2016, GB 4806.7-2016, GB 4806.1-2016, and GB 31603-2015. Furthermore, in some embodiments, the base polymer is polypropylene and the mineral desiccant is a molecular sieve, such as 3A molecular sieve. In any embodiment, the integral composition may be completely free of any colorants to comply with any applicable food material regulations or standards.

[0036] Optionally, the base polymer comprises 35-45% by weight, optionally 37-43% by weight, optionally 39-41% by weight, optionally 40% by weight, or about 40% by weight of the total composition; the mineral desiccant comprises 50-60% by weight, optionally 50-56% by weight, optionally 51-55% by weight, optionally 54-55% by weight, optionally 54% by weight, or about 54% by weight, or about 55% by weight, or about 55% by weight of the total composition; and the EVA channel forming agent comprises 2-10% by weight, optionally 3-8% by weight, optionally 4-6% by weight, optionally 5% by weight, or about 5% by weight of the total composition. Optionally, the base polymer is polypropylene and comprises about 40% by weight of the total composition; the mineral desiccant is molecular sieve and comprises about 55% by weight of the total composition; and the EVA channel forming agent comprises about 5% by weight of the total composition, wherein the total amount of molecular sieve, polypropylene, and EVA comprises 100% by weight of the total composition. In a further embodiment, polypropylene accounts for 40% by weight of the total composition, molecular sieve accounts for 55% by weight of the total composition, and EVA accounts for 5% by weight.

[0037] refer to Figure 1 An insert 20 constructed from an entrained polymer, which may be used according to optional aspects of the disclosed concepts, is shown. The insert 20 is in the form of a plug 55. It should be understood that the plug 55 represents only an optional configuration of the entrained polymer component, and the entrained polymer can be formed in different configurations and shapes, such as piercing elements, as discussed below.

[0038] refer to Figure 2 A cross-sectional view is shown of a plug 55 constructed from an entrained polymer 10 comprising a base polymer 25 uniformly blended with a mineral desiccant 30 and a hydrophilic agent or channel forming agent 35. Figure 2 In this example, the entrained polymer has been cured, such that interconnecting channels 45 have been formed throughout the entrained polymer 10, thereby establishing a pathway through the cured plug 55. From these two... Figure 1 and Figure 2 It can be seen that the passage terminates at the channel opening 48 on the outer surface of plug 55.

[0039] Figure 3 It shows the similarity in construction and composition to Figure 2 An alternative embodiment of plug 55 similar to plug 55, wherein interconnect channel 45 is... Figure 2The interconnecting channels are very fine compared to other materials. This is likely due to the use of a dimerizing agent (i.e., a plasticizer) with channel forming agent 35. The dimerizing agent enhances the compatibility between the base polymer 25 and the channel forming agent 35. This enhanced compatibility is facilitated by a lower viscosity blend, which promotes a more thorough blending of the base polymer 25 and the channel forming agent 35, which under normal conditions can resist combining into a homogeneous solution. When the entrained polymer 10 with the dimerizing agent added is cured, the interconnecting channels 45 formed therethrough have greater dispersion and smaller porosity, thereby establishing a higher density of interconnecting channels throughout the plug 55.

[0040] Interconnecting channels 45, as disclosed herein, facilitate the transport of desired materials, such as moisture, gases, or odors, throughout the base polymer 25, which typically resists the penetration of these materials, thus acting as a barrier. For this reason, the base polymer 25 itself acts as a barrier material in which the mineral desiccant 30 can be entrained. The interconnecting channels 45 formed by the channel forming agent 35 provide pathways for the movement of desired materials through the entrained polymer 10. Without these interconnecting channels 45, it is believed that a relatively small amount of desired material would be transported through or from the base polymer 25 to the mineral desiccant 30. In the case where the desired material is transported to the mineral desiccant 30, it can be absorbed by the mineral desiccant 30.

[0041] Now for reference Figure 5 and Figure 6 The illustration shows an optional embodiment of packaging 110 according to the disclosed concept. In the illustrated embodiment, packaging 110 is a cap configured to serve as a closure for a container. However, in alternative embodiments, packaging 110 may be a vial or bottle. When packaging 110 is a bottle, the bottle may be formed by a blow molding process. Figure 5 The packaging 110 is shown before the product is filled and sealed. Figure 6 Package 110 in a sealed position is shown. Package 110 may have any suitable configuration or orientation for containing the product therein. Optionally, in any embodiment, package 110 has a relatively small internal volume, for example, less than 25 mL, optionally less than 20 mL, optionally 5 mL to 20 mL, optionally 8 mL to 15 mL.

[0042] Package 110 includes an outer shell. The outer shell has a base 112 and sidewalls 114 extending therefrom, thereby defining an internal space 118 within package 110. Package 110 may include an opening 116 leading to the internal space 118 before being sealed. Figure 6As shown, when in the sealed position, package 110 optionally includes a lid 120 that seals the product 126 stored within the internal space 118. Optionally, in any embodiment, product 126 is a powder, such as a moisture-sensitive powder. Specifically, product 126 in powder form may be a probiotic, i.e., a powder containing live microorganisms that, when applied in sufficient quantities, confer health benefits to the host. Optionally, the powder may contain vitamins or other nutritional supplements or food in powder form. Additionally, product 126 in powder form may contain a moisture-sensitive active pharmaceutical ingredient (API), such that a mineral desiccant will maintain the shelf life of the API.

[0043] The cover 120 is optionally secured to the periphery of the opening 116 by a heat seal 122. The heat seal 122 (if used) can be applied by an inductive sealing process, as is known to those skilled in the art. Optionally, the cover 120 is made of foil.

[0044] Package 110 also includes a piercing element 130 disposed within the internal space 118. The piercing element 130 includes a cutting edge or tip 132 facing the cap 120. When package 110 is in the sealed position, the cutting edge or tip 132 optionally proximates or even contacts the cap 120. The piercing element 130, optionally including the cutting edge or tip 132, is composed of a mineral-loaded polymer comprising a monolithic material formed from at least a base polymer and a mineral desiccant, as described herein.

[0045] Optionally, in any embodiment, the bulk material comprises a channel forming agent. Optionally, in any embodiment, the mineral desiccant is a molecular sieve, such as a 3A or 4A molecular sieve, or silica gel, although 3A molecular sieves have been found to be preferred for small-volume applications, as described in Example 2 below. The mineral desiccant is a desiccant that absorbs moisture from the internal space 118 of the packaging 110 to maintain the desired quality of the product 126, such as prolonging the freshness of the product and / or (in the case of powder) preventing the product from clumping or agglomerating. Optionally, in any embodiment, the lid 120 comprises one or more layers, which may include paper, card, plastic, foil, or a combination of one or more of the foregoing. Optionally, in any embodiment, the lid is flexible and has a thickness of 0.01 mm to 1.00 mm, optionally 0.01 mm to 0.40 mm.

[0046] Now for reference Figure 7 and Figure 8 The following embodiment is shown, wherein packaging 110 is a cap suitable for use as a closure of container 134, which can be used according to a method for dispensing product 126 from packaging 110 into container 134. In the illustrated embodiment, container 134 is a bottle, and the dispensed product 126 is powder stored in the internal space 118 of packaging 110.

[0047] In an optional method, pressure is applied to the cap 120 in a direction perpendicular to the cutting edge or tip 132. Optionally, this can be achieved by applying pressure to the base 112 of the cap, causing the cutting edge or tip 132 to exert force on the cap 120. In any case, the aforementioned pressure applied to the cap 120 in a direction perpendicular to the cutting edge or tip 132 causes the cutting edge or tip 132 to pierce the cap 120 or separate a portion of the cap 120 from the package 110. This, in turn, changes the package 110 from a sealed position to a dispensing position, in which the product 126 is dispensed through the opening 116.

[0048] Optionally, product 126 is dispensed into container 134 below packaging 110 and filled with liquid 136. Optionally, product 126 is mixed with liquid 136 to form a solution.

[0049] Optionally, in any embodiment, the base polymer is polypropylene, for example, S-1005 P.

[0050] Optionally, in any embodiment, the disclosed concept broadly relates to piercing elements (e.g., 130) having a cutting edge or tip (e.g., 132), wherein the piercing element (optionally, the entire piercing element, preferably including the cutting edge or tip) is composed of a mineral-loaded polymer comprising a monolithic material formed of at least a base polymer and a mineral desiccant. The disclosed concept is not limited to the use of piercing elements in packaging (e.g., 110), but this is currently its preferred application.

[0051] Optionally, in any embodiment of the piercing element, the mineral loading level of the mineral-loaded polymer accounts for at most 60% by weight, optionally 20% to 55% by weight, and optionally 30% to 50% by weight of the total material. Optionally, in any embodiment of the piercing element, if the piercing element has a tip (i.e., a point, etc.), the diameter or cross-sectional width of the tip is less than 1.0 mm, optionally less than 0.75 mm, optionally 0.01 mm to 0.75 mm, and optionally 0.03 mm to 0.5 mm. Optionally, in any embodiment of the piercing element, if the piercing element has a cutting edge (i.e., a blade), the width of the cutting edge is less than 1.0 mm, optionally less than 0.75 mm, optionally 0.01 mm to 0.75 mm, and optionally 0.03 mm to 0.5 mm. Optionally, in any embodiment, the piercing element is configured to pierce a 40-micron-thick aluminum foil cap without breaking when sufficient pressure is applied. Optionally, the disclosed concepts relate to using any embodiment of the piercing element disclosed herein to pierce a cap, optionally piercing the cap (e.g., 120) of a sealed package (e.g., 110).

[0052] The following exemplary embodiments further describe optional aspects of the technology of this disclosure and are part of this detailed description. These exemplary embodiments are set forth in a format substantially similar to that of the claims, but are not technically claims of this application. The following exemplary embodiments are referred to as “embodiments” rather than “claims” in a dependent relationship.

[0053] 1A. A desiccant-encapsulated polymer assembly comprising an integral composition formed of at least a base polymer and a mineral desiccant.

[0054] 2A. The desiccant encapsulated polymer component of Example 1A, wherein the base polymer accounts for 35-45% by weight, optionally 37-43% by weight, optionally 39-41% by weight, optionally 40% by weight, or about 40% by weight of the total material.

[0055] 3A. The desiccant encapsulated polymer assembly of Example 1A or 2A, wherein the base polymer is made of polypropylene.

[0056] 4A. The desiccant-encased polymer component of any one of Examples 1A-3A, wherein the mineral desiccant accounts for 50-60% by weight, optionally 50-56% by weight, optionally 51-55% by weight, optionally 54-55% by weight, optionally 54% by weight, or about 54% by weight, or 55% by weight, or about 55% by weight of the total material.

[0057] 5A. A desiccant-encapsulated polymer component in any of Examples 1A-4A, wherein the mineral desiccant is a molecular sieve.

[0058] 6A. The desiccant encapsulated polymer assembly of Example 5A, wherein the molecular sieve is 3A molecular sieve.

[0059] 7A. The desiccant encapsulated polymer assembly of Example 5A, wherein the molecular sieve is 4A molecular sieve.

[0060] 8A. A desiccant-encapsulated polymer assembly of any one of Examples 1A-7A, wherein the integral material comprises a channel forming agent.

[0061] 9A. The desiccant-encased polymer assembly of Example 8A, wherein the channel forming agent accounts for 2-10% by weight, optionally 3-8% by weight, optionally 4-6% by weight, optionally 5% by weight, or about 5% by weight of the total material.

[0062] 10A. The desiccant entrained polymer assembly of Example 8A or 9A, wherein the channel forming agent is ethylene vinyl acetate.

[0063] 11A. A desiccant-encapsulated polymer assembly of any one of Examples 1A-10A, wherein the desiccant-encapsulated polymer assembly is free of colorant.

[0064] 12A. The desiccant encapsulated polymer component of any one of Examples 1A-11A, wherein the overall composition meets the requirements of the Chinese National Food Safety Standard GB 9685-2016: Standard for the Use of Additives in Food Contact Materials and Articles.

[0065] 13A. The desiccant encapsulated polymer component of any one of Examples 1A-12A, wherein the overall composition meets the requirements of Chinese National Food Safety Standard GB 4806.6-2016 Plastic Resins for Food Contact.

[0066] 14A. The desiccant encapsulated polymer component of any one of Examples 1A-13A, wherein the overall composition meets the requirements of Chinese National Food Safety Standard GB 4806.7-2016 Plastic Materials and Articles for Food Contact.

[0067] 15A. The desiccant encapsulated polymer component of any one of Examples 1A-14A, wherein the overall composition meets the requirements of the Chinese National Food Safety Standard GB 4806.1-2016 General Safety Requirements for Food Contact Materials Applicable to Food Contact Additives.

[0068] 16A. The desiccant encapsulated polymer component of any one of Examples 1A-15A, wherein the overall composition meets the requirements of the Chinese National Food Safety Standard GB 31603-2015 General Hygiene Specification for the Production of Food Contact Materials and Articles.

[0069] 17A. A desiccant-encapsulated polymer assembly of any one of Examples 1A-16A, wherein the desiccant-encapsulated polymer assembly is encapsulated within a package.

[0070] 18A. The desiccant-encapsulated polymer assembly of Example 17A, wherein the package further contains the product encapsulated in the package by a packaging insert.

[0071] 19A. Desiccant encapsulated polymer assembly of Example 18A, wherein the product is a powder and a packaging insert controls moisture within the packaging.

[0072] 20A. A desiccant-encapsulated polymer assembly of any one of Examples 1A-19A, wherein the packaging insert includes a puncture element.

[0073] 21A. A desiccant-encased polymer assembly of any one of Examples 17A-19A, wherein the desiccant-encased polymer assembly includes a puncture element configured to puncture the package.

[0074] 22A. A desiccant-encapsulated polymer assembly of any of Examples 20A-21A, wherein the piercing element is sufficiently rigid to pierce the cap.

[0075] 23A. A desiccant encapsulated polymer component in any of Examples 17A-22A, wherein the container is fixed to the packaging such that the packaging acts as a closure of the container.

[0076] 24A. The desiccant encapsulated polymer assembly of Example 23A, wherein the container is filled with liquid.

[0077] 25A. A desiccant-encapsulated polymer assembly of any of Examples 20A-23A, wherein the piercing element comprises one or more cutting blades.

[0078] The various aspects of the invention are further illustrated in more detail with reference to the following examples, but it should be understood that the invention is not to be considered limited thereto.

[0079] Example Example 1 Fifty (50) desiccant-filled tool parts were molded and tested to ensure compliance with GB 4806.7-2016. The tool parts were made from the following formulation: Table 1 Given the failure of previous GB migration tests using PEG as a channel forming agent, the inventors chose EVA as a channel forming agent for the test based on their insight that EVA can avoid migration from cutter parts into the liquid.

[0080] The cutter component is placed in a 100 mL container with a sealing surface area of ​​0.350 dm². 2 The total contact area of ​​the sealed product and the sealed container is 1.66592 dm². 2 The contents are in a sealed container. This study considers the intended use to be as a powdered food or a nutritional supplement in powder form (e.g., probiotics or vitamins).

[0081] As used in this example, LOD / LOQ = Limit of Detection / Limit of Quantification, ND = Not Detected (below LOD / LOQ). Food simulants are sourced from GB 4806.7-2016 and GB 31604.1-2015. Test conditions are sourced from GB 4806.7-2016. Test results are listed in the table below.

[0082] Table 2 Sensory requirements Conventional physicochemical indicators Table 3 Total migration (test conditions: 10% (v / v) ethanol, 40℃, 10d) Table 4 Potassium permanganate consumption (test conditions: water, 60℃, 2h) Table 5 Heavy metal - Pb (Test conditions: 4% (v / v) acetic acid, 60℃, 2h) Table 6 Decolorization test Specific migration Test conditions: 10% (v / v) ethanol, 60℃, 10 days In summary, the foregoing embodiments particularly demonstrate that the cutting tool components according to optional aspects of the disclosed concept meet the sensory requirements, conventional physicochemical properties, and vinyl acetate migration of GB4806.7-2016.

[0083] Example 2 Advantages of 3A molecular sieves in small-volume packaging Knife components made from the formulations in Table 1 were stored and sealed in small polymer packages, with the foil cap heat-sealed to the edge around the package opening. Other knife components were tested in the same manner, except that these included 4A molecular sieves instead of 3A and PEG as a channel-forming agent instead of EVA. The empty volume of all tested packages was approximately 10 to 15 mL. The volume of the knife component was approximately 20% of the empty volume of the package. It was found that the foil cap of the package used with 4A molecular sieves deformed due to overpressure within the cap. The inventors speculate that this was due to the 4A molecular sieve releasing gas when the ambient temperature increased. No such deformation of the foil cap was observed in the samples using 3A molecular sieves as the desiccant. This demonstrates the significant utility of using 3A molecular sieves in desiccant-encapsulated polymer formulations for foil-sealed packages with relatively small volumes (e.g., less than 20 mL).

[0084] Although the invention has been described in detail with reference to specific examples thereto, it will be apparent to those skilled in the art that various changes and modifications may be made thereto without departing from its spirit and scope.

Claims

1. A package comprising: a. An outer shell that defines the internal space; b. A desiccant-entrained polymer component disposed within the internal space, the desiccant-entrained polymer component comprising an integral composition of a base polymer, a mineral desiccant, and an ethylene-vinyl acetate (EVA) channel forming agent, wherein the base polymer comprises 35-45% by weight, optionally 37-43% by weight, optionally 39-41% by weight, optionally 40% by weight, or about 40% by weight of the integral composition; the mineral desiccant comprises 50-60% by weight, optionally 50-56% by weight, optionally 51-55% by weight, optionally 54-55% by weight, optionally 54% by weight, or about 54% by weight, or 55% by weight, or about 55% by weight of the integral composition; the EVA channel forming agent comprises 2-10% by weight, optionally 3-8% by weight, optionally 4-6% by weight, optionally 5% by weight, or about 5% by weight of the integral composition; the water vapor permeability of the EVA channel forming agent is greater than that of the base polymer; and the integral composition comprises interconnected channels formed by the EVA channel forming agent; and c. A product in powder form disposed within the internal space; The desiccant encapsulates polymer components to remove moisture from the packaging to maintain the desired quality of the product; and The desiccant-encapsulated polymer component described herein complies with at least one regulatory standard selected from the group consisting of: i. China's National Food Safety Standard GB 9685-2016: Standard for the Use of Additives in Food Contact Materials and Articles; ii. Chinese National Food Safety Standard GB 4806.6-2016 for plastic resins used in food contact; iii. Chinese National Food Safety Standard GB 4806.7-2016 for Plastic Materials and Products for Food Contact; iv. Chinese National Food Safety Standard GB 4806.1-2016, which addresses the general safety requirements for food contact materials applicable to food contact additives; and v. China's national food safety standard GB 31603-2015, which provides general hygiene guidelines for the production of food contact materials and articles.

2. The packaging according to claim 1, wherein the desiccant-enclosed polymer component is in direct contact with the product.

3. The packaging according to claim 1 or 2, wherein the desiccant entrained polymer component is free of colorants.

4. The packaging according to any of the preceding claims, wherein the mineral desiccant is a molecular sieve and the base polymer is polypropylene.

5. The packaging according to claim 4, wherein the molecular sieve comprises about 55% by weight of the total composition, the polypropylene comprises about 40% by weight of the total composition, and the EVA comprises about 5% by weight of the total composition, wherein the sum of the molecular sieve, polypropylene and EVA comprises 100% by weight of the total composition.

6. The packaging according to claim 4, wherein the molecular sieve comprises 55% by weight of the total composition, the polypropylene comprises 40% by weight of the total composition, and the EVA comprises 5% by weight of the total composition.

7. The packaging according to any one of claims 4 to 6, wherein the molecular sieve is a 3A molecular sieve.

8. The packaging according to any of the preceding claims, wherein the product comprises probiotics, vitamins or other nutritional supplements.

9. The packaging according to any one of claims 1 to 7, wherein the product contains a drug API that is unstable with moisture, and wherein the mineral desiccant maintains the shelf life of the product.

10. The packaging according to any of the preceding claims, wherein the packaging is a vial.

11. The packaging according to any one of claims 1 to 9, wherein the packaging is a bottle.

12. The packaging according to claim 11, wherein the bottle is formed by a blow molding process.

13. A container component comprising: a. A cap suitable for use as a closure for containers; b. The cap defines the internal space; c. A desiccant-entrained polymer component disposed within the internal space, the desiccant-entrained polymer component comprising an integral composition of a base polymer, a mineral desiccant, and an ethylene-vinyl acetate (EVA) channel forming agent, wherein the base polymer comprises 35-45% by weight, optionally 37-43% by weight, optionally 39-41% by weight, optionally 40% by weight, or about 40% by weight of the integral composition; the mineral desiccant comprises 50-60% by weight, optionally 50-56% by weight, optionally 51-55% by weight, optionally 54-55% by weight, optionally 54% by weight, or about 54% by weight, or 55% by weight, or about 55% by weight of the integral composition; the EVA channel forming agent comprises 2-10% by weight, optionally 3-8% by weight, optionally 4-6% by weight, optionally 5% by weight, or about 5% by weight of the integral composition; the water vapor permeability of the EVA channel forming agent is greater than that of the base polymer; and the integral composition comprises interconnected channels formed by the EVA channel forming agent. d. The desiccant-encapsulated polymer component is a piercing element, the piercing element comprising a cutting blade or tip configured to pierce a portion of the cap to dispense the powdered product into the container; and e. A product in powder form disposed within the internal space; The desiccant encapsulating the polymer component removes moisture from the packaging to maintain the desired quality of the product; and The desiccant-encapsulated polymer component described herein complies with at least one regulatory standard selected from the group consisting of: i. China's National Food Safety Standard GB 9685-2016: Standard for the Use of Additives in Food Contact Materials and Articles; ii. Chinese National Food Safety Standard GB 4806.6-2016 for plastic resins used in food contact; iii. Chinese National Food Safety Standard GB 4806.7-2016 for Plastic Materials and Products for Food Contact; iv. Chinese National Food Safety Standard GB 4806.1-2016, which addresses the general safety requirements for food contact materials applicable to food contact additives; and v. China's national food safety standard GB 31603-2015, which provides general hygiene guidelines for the production of food contact materials and articles.

14. The packaging according to any one of claims 1 to 12 or the container assembly according to claim 13, wherein the desiccant-encapsulated polymer component is injection molded.

15. The packaging or container assembly of claim 14, wherein the desiccant-encased polymer component has a maximum thickness of at least 2 mm and a width and height each greater than said thickness.

16. A method for dispensing a product from a cap into a container, the method comprising: a. Providing a product within the internal space defined by the cap, wherein the product is in powder form; b. Providing a piercing element within the internal space of the cap, the piercing element having a cutting edge or tip, the piercing element being made of a desiccant-encapsulated polymer comprising an integral composition of a base polymer, a mineral desiccant, and an ethylene-vinyl acetate (EVA) channel forming agent, wherein the base polymer comprises 35-45% by weight, optionally 37-43% by weight, optionally 39-41% by weight, optionally 40% by weight, or about 40% by weight of the integral composition, and the mineral desiccant comprises 5% by weight of the integral composition. The EVA channel forming agent comprises 0-60% by weight, optionally 50-56% by weight, optionally 51-55% by weight, optionally 54-55% by weight, optionally 54% by weight or about 54% by weight or 55% by weight or about 55% by weight of the total composition, wherein the EVA channel forming agent accounts for 2-10% by weight, optionally 3-8% by weight, optionally 4-6% by weight, optionally 5% by weight or about 5% by weight of the total composition, wherein the water vapor permeability of the EVA channel forming agent is greater than that of the base polymer, and the total composition comprises interconnected channels formed by the EVA channel forming agent; c. Enclose the product and the piercing element within the internal space; d. Secure the cap to the container, wherein the container contains liquid; e. Manipulate the piercing element to pierce a portion of the cap and release the product into the container.

17. The method of claim 16, wherein the mineral desiccant is 3A molecular sieve and the base polymer is polypropylene.

18. The method of claim 17, wherein the 3A molecular sieve comprises about 55% by weight of the total composition, the polypropylene comprises about 40% by weight of the total composition, and the EVA comprises about 5% by weight of the total composition, wherein the total of the molecular sieve, polypropylene, and EVA comprises 100% by weight of the total composition.

19. The method according to any one of claims 16 to 18, wherein the product and the piercing element are enclosed within the internal space by a cover, the cover optionally being a foil cover, the foil cover being heat-sealed to the edge surrounding the opening leading to the internal space.

20. The method of claim 19, wherein the step of manipulating the piercing element to pierce a portion of the cap and releasing the product into the container comprises moving the piercing element downward to contact and pierce the cap.

21. The method according to any one of claims 16 to 20, wherein the internal space has a volume of less than 25 mL, optionally less than 20 mL, optionally from 5 mL to 20 mL, or optionally from 8 mL to 15 mL.

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