Agglutination experiment board and board frame thereof

Abstract

The utility model relates to the technical field of animal disease prevention and control biological experiment tools, and discloses an agglutination experiment board and a board frame thereof, which comprise a reaction board and a board frame. The reaction plate is of a whole-body transparent structure, lug type limiting and fixing devices are arranged on the two sides of the upper end of the reaction plate, and the upper surfaces of the lug type limiting and fixing devices are mark surfaces of ground glass-shaped plane structures. A plurality of reaction holes arranged in an array are formed in the reaction plate, each reaction hole is of a hollow and concave vertical cuboid structure, and an opening of each reaction hole is of a flat rectangular structure. The plate frame is composed of a plate frame panel and reinforcing ribs, the plate frame panel is made of transparent materials, a plurality of limiting and fixing clamping grooves are distributed in the upper end of the plate frame panel in an array mode, and the four corners of the plate frame panel are connected through the four reinforcing ribs. According to the utility model, detection personnel can conveniently judge the result of the agglutination experiment, and the high-throughput detection of the agglutination experiment can be met.

Description

Technical Field

[0001] The utility model relates to the technical field of biological experimental tools for animal disease prevention and control, in particular to an agglutination experimental plate and a plate frame thereof. Background Art

[0002] Agglutination test is a common detection method used by detection technicians for disease prevention, diagnosis and monitoring. Its principle is to generate agglutinated particles or flocculent precipitation by interaction between the detected sample and the detection reagent components based on the specific binding characteristics of antigen and antibody. For example, particulate antigens such as bacteria and red blood cells directly bind to the corresponding antibodies to produce agglutination. The positive or negative of the detected sample is determined by the generation of agglutinated particles or flocculent precipitation, thereby determining the infection status or antibody level of the sampled animal. Through agglutination experiments, animal diseases can be identified quickly, accurately and effectively, and the infection status or immune status of animals can be determined, which can assist clinical diagnosis and epidemiological investigation and research, so as to treat animals and purify diseases in the later stage.

[0003] Agglutination experiments are divided into glass slide method and test tube agglutination method. The main experimental tools used in the glass slide method are glass plates, and the main experimental tools used in the test tube agglutination method are test tubes and test tube racks. Existing glass slide type agglutination test flat products include glass plates, disposable agglutination test cards, 96-well disposable agglutination test plates, etc. Glass plates are easy to use, the results are better, and the liquid adsorption is not obvious, but they are easy to damage, and the liquid is easy to flow out when the glass plate is tilted. The glass plate material is relatively thick and heavy, and it is no longer produced on the market. There are many problems with disposable agglutination test cards in actual use, mainly manifested in that the test card is easy to bend and move, causing the added liquid to flow or cause pollution, the test card is opaque, and the liquid is easy to condense after adding the sample, which is not convenient for observation, and the liquid loss is large due to cardboard adsorption after adding the sample. Although the 96-well disposable agglutination test plate has a high-throughput design, there are too many 96-well reaction wells, which is easy to cause resource waste for the detection of a small number of samples. The test tubes used in the test tube agglutination experiment are mainly made of glass, which are easily damaged. In addition, the test tubes and test tube racks take up a lot of space, and it is not convenient to take photos and preserve images later.

[0004] Therefore, it is necessary to design a convenient, durable and easy-to-observe experimental tool as a reaction carrier for agglutination experiments to solve the above-mentioned problems such as being heavy, easy to damage, easy to flow or adsorb liquid, inconvenient to observe, and waste of resources. Summary of the invention

[0005] In view of the defects of existing product technology, the utility model provides an agglutination test plate and a plate rack thereof, which solve the problems raised in the above background technology, such as the glass plate is easy to be damaged, the liquid is easy to flow out and is relatively thick, the disposable agglutination test card is easy to bend and move, causing liquid to flow or be contaminated, the results are inconvenient to observe and the liquid loss is large after adding the sample, the 96-well disposable agglutination test plate is easy to cause waste of resources, the test tube is easy to be damaged, the test tube and the test tube rack take up a lot of space, and it is inconvenient to take pictures later.

[0006] To achieve the above purpose, the utility model is implemented through the following technical solutions: an agglutination test plate and a plate rack thereof, including an agglutination test reaction plate and a plate rack. Further, the reaction plate is a transparent structure throughout, with ear-type limit fixing devices on both sides of the upper end, and the upper surface of the ear-type limit fixing device is a marking surface of a frosted glass-like plane structure. Further, there are a plurality of reaction wells arranged in an array on the reaction plate, and preferably, the reaction wells are hollow and concave vertical rectangular structures. Further, the plate rack is composed of a plate rack panel and reinforcing ribs, the plate rack panel is made of a transparent material, and a plurality of limit fixing slots are arranged in an array on the upper end, and the four corners of the plate rack panel are connected by four reinforcing ribs.

[0007] The utility model provides an agglutination test plate and a plate frame thereof, which have the following beneficial effects.

[0008] The agglutination test plate and its plate rack can facilitate the mixing of experimental components by designing hollow vertical flat rectangular reaction holes, and the reaction results can be observed intuitively over a large area. Furthermore, the vertical flat reaction hole design can effectively prevent the loss or outflow of experimental component liquids.

[0009] The agglutination test plate and its plate rack can conveniently fix the agglutination test plate on the plate rack through the ear-type limiting fixing devices on both sides of the reaction plate and the limiting fixing slots on the plate rack. Furthermore, the plate rack is a rectangular three-dimensional structure, which can stably carry the agglutination test plate and avoid tipping, and the space between the plate rack panels except for the connection of the reinforcing ribs is a hollow structure, which can facilitate the observation of the experimental results.

[0010] The agglutination test plate and its plate rack have a plurality of reaction holes on the reaction plate, which is convenient for comparative observation. Furthermore, multiple agglutination test plates can be placed on the plate rack according to the number of test samples, so as to meet the needs of a large number of sample tests and reduce resource waste.

[0011] The agglutination test plate and its plate rack, the ear-type limiting fixtures at both ends of the reaction plate are provided with marking surfaces. Further, the marking surface is a frosted glass-like plane structure, which can be used to conveniently mark the experiment, and the marking symbol is not easy to wipe off with this plane design.

[0012] The agglutination test plate and its plate rack have a certain spacing between the limit fixing slots on the plate rack, and can meet the high-throughput detection of agglutination experiments in conjunction with a multi-channel pipette with adjustable spacing. Furthermore, a common pure color control bottom plate can be added to the gap between two adjacent reaction plates, making it more convenient to observe the experimental results.

[0013] The agglutination test plate and the plate frame thereof are made of a transparent, wear-resistant, reusable new material and can be reused after cleaning, thereby reducing the experimental cost and the waste of resources. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a schematic diagram of the overall structure of the agglutination test plate and its frame of the utility model;

[0015] Figure 2 This is a perspective schematic diagram of the overall structure of the reaction plate of the utility model;

[0016] Figure 3 It is a schematic diagram of the overall structure of the plate frame of the utility model.

[0017] In the figure: 1. reaction plate; 2. plate rack; 101. ear-type limit fixing device; 102. marking surface; 103. reaction hole; 201. reinforcing rib; 202. plate rack panel; 203. limit fixing slot.

[0018] Specific implementation method.

[0019] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0020] See also Figures 1 to 3The utility model provides a technical solution: an agglutination test plate and a plate rack thereof, comprising a reaction plate (1) and a plate rack (2). Furthermore, the reaction plate (1) is provided with a plurality of reaction wells (103) arranged in an array, and the reaction wells (103) are hollow, concave, vertical rectangular structures. Furthermore, the openings of the reaction wells (103) are flat rectangular structures and are flush with the upper surface of the reaction plate (1), so that the agglutination test results can be observed very conveniently, and the agglutination conditions can be displayed intuitively and three-dimensionally over a large area, meeting the requirements of multiple sample detection and comparison of experimental results, and at the same time, can effectively prevent the liquid in the reaction wells (103) from flowing out, thereby reducing the loss of experimental component liquid. Furthermore, covering the reaction plate (1) with a sealing film can prevent the loss of experimental components in the reaction wells (103). Furthermore, ear-type limiting fixing devices (101) are provided on both sides of the upper end of the reaction plate (1), and the reaction plate (1) can be stably placed in the plate frame (2) and not easily tipped over by means of the ear-type limiting fixing devices (101) and the limiting fixing slots (203) on the plate frame (2). Furthermore, the upper surface of the ear-type limiting fixing device (101) has a marking surface (102), and the marking surface (102) is a frosted glass-like plane structure, which can be convenient for detection personnel to mark and is not easy to wipe off.

[0021] Furthermore, the plate rack (2) is a rectangular three-dimensional structure, the reinforcing ribs (201) are connected to the plate rack panel (2) in a vertical direction, and the outer surface of the reinforcing ribs (201) is flush with the outer surface of the connected plate rack panel (202), so that the plate rack (2) can be stably placed on the test bench and not easily tipped over. Furthermore, there are a plurality of limit fixing slots (203) on the plate rack (2), which can simultaneously meet the placement requirements of multiple reaction plates and can simultaneously test multiple samples. Furthermore, the space between the plate rack panels (202) except for the connection of the reinforcing ribs (202) is a hollow structure, which can facilitate the observation and comparison of the experimental results of the reaction plate (1).

[0022] Furthermore, the material of the agglutination test plate is a transparent, wear-resistant, reusable new material, such as TPU, engineering plastics, resin, renewable polycarbonate, etc.

[0023] In the utility model, the steps of using the agglutination test plate and the plate rack thereof are as follows.

[0024] First, place the plate rack on the laboratory bench, take out the reaction plate and load it into the plate rack, pipette the detection reagent into the reaction well, then pipette the sample to be tested into the reaction well, stir and mix with a pipette tip or a mixing device, or gently shake the plate rack to fully mix the detection reagent and the sample to be tested, and control the liquid volume in the reaction well according to different experimental specifications.

[0025] Then, cover the upper surface of the reaction plate with a sealing film, a glass plate, or other materials commonly used in laboratories to prevent liquid loss, and leave it alone until the time requirements specified in the experimental test specifications are met.

[0026] Finally, directly observe the agglutination test results, or shake the plate rack to observe the agglutination, or take out the reaction plate to observe the agglutination, or add a pure color baffle or light source to the back of the reaction plate, so that the agglutination can be observed more clearly and the image data of the experimental results can be taken.

[0027] If there are many samples to be tested, multiple plate racks can be used and multiple reaction plates can be placed on the plate racks to meet the needs of testing a large number of samples at the same time.

[0028] After the experiment is completed and the reaction plate is used up, the experimental components in the reaction wells should be disposed of in accordance with the laboratory waste disposal regulations, the reaction plate should be rinsed or ultrasonically cleaned, and can be reused after being dried or baked.

[0029] It should be noted that although typical embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to these embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An agglutination test plate and a plate stand thereof, characterized in that: The invention comprises a reaction plate (1) and a plate frame (2), wherein the reaction plate (1) is provided with a plurality of reaction holes (103) arranged in an array, and the plate frame (2) is composed of two plate frame panels (202) connected by four reinforcing ribs (201).

2. The agglutination test plate and the plate stand thereof according to claim 1, characterized in that: Ear-type limiting fixing devices (101) are provided on both sides of the upper end of the reaction plate (1).

3. The agglutination test plate and the plate stand thereof according to claim 1, characterized in that: The reaction hole (103) is a hollow, concave vertical rectangular structure. The opening of the reaction hole (103) is a flat rectangular structure and is flush with the upper surface of the reaction plate (1). The bottom of the reaction hole (103) is a flat structure.

4. The agglutination test plate and the plate stand thereof according to claim 2, characterized in that: The upper surface of the ear-type limiting and fixing device (101) is a marking surface (102) of a frosted glass-like plane structure, and the marking surface (102) is flush with the upper surface of the reaction plate (1).

5. The agglutination test plate and the plate stand thereof according to claim 1, characterized in that: The upper end of the plate frame (2) is provided with a plurality of position-limiting and fixing slots (203), wherein the position-limiting and fixing slots (203) are concave slot-type structures, and a certain distance is provided between two adjacent position-limiting and fixing slots (203).

6. The agglutination test plate and the plate stand thereof according to claim 1, characterized in that: The panel frame (2) is a rectangular three-dimensional structure, and the reinforcing rib (201) is a rectangular parallelepiped structure, which is connected to the panel frame panel (202) in a vertical direction, and the outer surface of the reinforcing rib (201) is flush with the outer surface of the connected panel frame panel (202).

7. The agglutination test plate and the plate stand thereof according to claim 1, characterized in that: The reaction plate (1) and the plate frame (2) are made of a transparent, wear-resistant, reusable new material, such as TPU, engineering plastics, resin, and renewable polycarbonate.

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