High-pressure connector for Sanger sequencer
By designing a high-pressure joint for Sanger sequencer using interference fit connection and high-pressure silicone seal, the existing high-pressure joints have solved the problem of complex structure and difficult to maintain stability in high pressure, achieving a simple, compact and stable high pressure effect.
Patent Information
- Application Number
- CN202323546590.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2023-12-25
- Publication Date
- 2025-02-18
- Estimated Expiration
- 2033-12-25
AI Technical Summary
The existing high-voltage joints have complex structures, difficult to install and use, and difficult to maintain stable high-voltage, and the actual boost is less than 20,000 volts.
A high-pressure joint for Sanger sequencer is designed, which uses a copper core to connect the matrix to the interference mating, and the end cap is connected to the substrate to the interference mating. The grooves in the substrate are filled with high-pressure silicone in advance, and the base is pressed into the matrix concave through the assembly end of the end cap. Grooves, extrude silicone, seal and fill gaps, achieving bonding, sealing and insulation effects.
It achieves a simple structure, compact, small space, and small use of parts. It reduces costs and is convenient for construction personnel to operate. It is suitable for a variety of high-voltage generators and generator cables to ensure the stability of high voltage and effective boosting of high voltage.
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Figure CN222508061U_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the field of high voltage generator accessories, in particular to a high voltage connector for a Sanger sequencer. Background Art
[0002] Gene sequencers based on Sanger technology require a 20,000-volt voltage difference to be applied to both ends of the capillary to allow DNA-level biological sample fragments to drift in the capillary; this requires a high-voltage generator. Currently, high-voltage generator manufacturers do not provide high-voltage connectors, so buyers / users must design and manufacture high-voltage connectors themselves;
[0003] There are two types of existing high-pressure joints, such as Figure 1-Figure 4 As shown:
[0004] Figure 1 The appearance is shown. Figure 2 The internal structure is shown. The main feature of this structure is that the high-voltage generator cable is welded into a copper core recess of a special structure. This copper core is the form required by the sequencer structure. When the copper core is slightly squeezed onto the electrode at one end of the capillary under the action of the compression spring, the movable lock needs to be rotated 90 degrees to lock the high-voltage connector in this state. In this way, the high voltage generated by the high-voltage generator is applied to one end of the capillary; the disadvantage of this structure is that screws and nuts are used, and a round nut is also used for internal connection. The technical solution is relatively traditional, and it is assembled from 10 parts. The structure is complex and requires a spacious space for installation and use; metal screws and nuts are also easy to discharge to the air, and it is difficult to keep the high voltage stable, and the actual rise is less than 20,000 volts;
[0005] Figure 3 The design is slightly improved compared to the above. Figure 4 The internal structure is shown, which uses a total of 4 parts, a copper core, a spring, a movable lock and a plastic base. It is more advanced than the first solution in that an interference fit is used internally to press the copper core into the plastic base, thus saving an internal round nut. At the same time, because there is no need for an upper round nut, the original end cap can be combined with the plastic base, saving both plastic parts and external screws and nuts. The disadvantage of this structure is that it has high requirements on the cable diameter of the high-voltage generator. Its diameter must be smaller than the small hole of the plastic interference fit, so that the cable can extend out of the plastic base and the movable lock, and be soldered into a whole with the copper core recessed hole. If the cable diameter is larger than the small hole of the interference fit, the cable wire must be manually peeled, causing inconvenience in production and increasing the workload of the operator. Summary of the invention
[0006] The object of the present invention is to provide a high-voltage connector for a Sanger sequencer to solve the problems in the prior art.
[0007] A high-voltage connector for a Sanger sequencer comprises a copper core, the copper core is provided with a movable lock buckle that can move along the axial direction of the copper core, one end of the copper core is provided with a concave hole that matches the core of a high-voltage cable, and one end of the copper core provided with the concave hole is sleeved with a base.
[0008] An end cap is also included, wherein the assembly end of the end cap is interference-fitted inside the base.
[0009] Furthermore, the base body is provided with a groove which is interference-fitted with the assembly end of the end cap.
[0010] The surface of the base groove is not higher than the surface of the copper core concave hole, and the inner hole structure of the base is abandoned, which is convenient for welding the cable and the copper core.
[0011] Furthermore, the groove is also used to fill with adhesive;
[0012] Furthermore, during the process of interference fitting of the end cap inside the base, the end cap squeezes the adhesive inside the groove into the gap between the end cap and the base, between the end cap and the high-voltage cable inserted in the recessed hole, between the copper core and the end cap, between the copper core and the base, and / or between the recessed hole and the high-voltage cable.
[0013] The copper core is connected to the base by interference fit, the end cap is connected to the base by interference fit, the groove in the base is filled with high-pressure silicone in advance, and when pressed into installation, the assembly end of the end cap is pressed into the groove of the base to squeeze the silicone and seal the gap to achieve the effect of bonding, sealing and insulation.
[0014] Furthermore, the adhesive may be a high-pressure silicone adhesive or an epoxy resin adhesive.
[0015] Furthermore, the assembly end of the end cap matches with one end of the copper core where the concave hole is arranged.
[0016] The traditional way of filling high-pressure joint adhesive is to fill from the outside to the inside. It is difficult for operators to judge the filling status of the small internal area. The adhesive of this solution is filled before installation. During the pressing process, the silicone flows from the inside to the outside to avoid the above situation.
[0017] Furthermore, a cavity adapted to the cable is provided through the clamping end of the end cap.
[0018] Furthermore, the clamping end is a flexible component that can movably clamp the cable.
[0019] Furthermore, the flexible component is rubber, a wing plate is provided on the flexible component, and a gap is provided between the wing plate and the end cap.
[0020] The flexible component facilitates the insertion of cables into the cavity, and the wing plate is tightened with the end cap by bolts, so that the cables can be easily fixed after being inserted.
[0021] Furthermore, the end cap is integrally formed.
[0022] Beneficial Effects
[0023] Compared with the prior art, the present invention has the following beneficial effects:
[0024] The present invention is simple and reasonable in structure. The copper core is connected to the base body by interference fit, the end cap is connected to the base body by interference fit, the groove in the base body is filled with high-pressure silica gel in advance, and when pressed into installation, the assembly end of the end cap is pressed into the base body groove to squeeze the silica gel and seal the filling gap, thereby achieving the effects of bonding, sealing and insulation.
[0025] At the same time, the present invention has a compact structure, occupies a small space, uses a small number of parts, reduces costs, and is convenient for construction personnel to operate, and is suitable for a variety of high-voltage generators and generator cables. BRIEF DESCRIPTION OF THE DRAWINGS
[0026] Figure 1 It is a schematic diagram of a high-voltage connector in which a cable is connected to a copper core through a nut in the prior art;
[0027] Figure 2 It is a cross-sectional view of a high-voltage connector in which a cable is connected to a copper core through a nut in the prior art;
[0028] Figure 3 A schematic diagram of a high-voltage connector in another prior art in which a cable is connected to a copper core through a plastic interference hole;
[0029] Figure 4 A cross-sectional view of a high-voltage connector in another prior art in which a cable is connected to a copper core through a plastic interference hole;
[0030] Figure 5 It is a schematic diagram of the three-dimensional structure of a high-voltage connector for a gene sequencer in the present invention;
[0031] Figure 6 This is a schematic diagram of the separation state of the end cap and the matrix in a high-voltage connector for a gene sequencer in the present invention;
[0032] Figure 7 This is a cross-sectional view of the overall structure of a high-voltage connector for a gene sequencer in the present invention.
[0033] In the figure: 1. copper core, 2. movable lock, 3. recessed hole, 4. base, 5. end cap, 6. groove, 7. wing plate, 8. high-voltage cable. DETAILED DESCRIPTION
[0034] In order to make the purpose, technical solutions and advantages of the present invention more clear, the present invention will be described in detail below with reference to the accompanying drawings and specific embodiments.
[0035] like Figure 5 As shown, a high-voltage connector for a Sanger sequencer includes a copper core 1, on which is provided a movable lock 2 that can move axially along the copper core 1, and an elastic component is provided at the assembly end of the copper core 1.
[0036] During installation, hold the active lock 2 for assembly. The copper core 1 is slightly squeezed to the electrode sheet at one end of the capillary by the elastic component. At this time, rotate the active lock 2 90 degrees to keep the high-voltage connector in this state.
[0037] The elastic component here can be a compression spring, a compression sponge, a compression elastic rubber sleeve, etc.
[0038] One end of the copper core 1 is provided with a recessed hole 3 which matches the core of the high-voltage cable 8. The high-voltage generator cable is installed in the recessed hole 3 of the copper core 1 and welded to the copper core 1. One end of the copper core 1 provided with the recessed hole 3 is sleeved with a base 4. The base 4 is made of plastic or metal and also includes an end cap 5. The assembly end of the end cap 5 is interference fit inside the base 4.
[0039] A groove 6 is provided inside the base body 4 and is interference-fitted with the assembly end of the end cap 5 .
[0040] like Figure 6 As shown, the groove 6 is also used to fill the adhesive;
[0041] During the process of interference fit of the end cap 5 inside the base 4, the end cap 5 squeezes the adhesive inside the groove 6 into the gap between the end cap 5 and the base 4, between the end cap 5 and the high-voltage cable 8 inserted in the recessed hole 3, between the copper core 1 and the end cap 5, between the copper core 1 and the base 4 and / or between the recessed hole 3 and the high-voltage cable 8.
[0042] The adhesive may be a high-pressure silicone adhesive or an epoxy resin adhesive.
[0043] like Figure 7 As shown, the assembly end of the end cap 5 matches with the end of the copper core 1 where the recessed hole 3 is provided.
[0044] The assembly end of the end cap 5 is tubular, and the groove 6 is filled with silicone. When the cable is installed, the silicone is filled in the groove 6, and the tubular assembly end of the end cap 5 is pressed into the groove 6 to squeeze the silicone. The silicone flows from the inside to the outside, changing the existing method of filling silicone from the outside to the inside. During the extrusion process, the silicone is pressed into the gap that needs to be sealed.
[0045] The clamping end of the end cap 5 is provided with a cavity adapted to the cable.
[0046] The clamping end is a flexible component that can movably clamp the cable.
[0047] The flexible component is rubber, and a wing plate 7 is provided on the flexible component. A movable gap is provided between the wing plate 7 and the end cap 5.
[0048] One or a pair of wing plates 7 are provided. When one side wing plate 7 is provided, the wing plate 7 is softly connected to the end cap 5 to facilitate the insertion of cables into the cavity. The wing plate 7 can be tightened with the end cap 5 by bolts to facilitate fixation after the cables are inserted.
[0049] When a pair of side wing plates 7 are provided, the two side wing plates 7 clamp the cables under the fixing of bolts.
[0050] The end cap 5 is integrally formed.
[0051] The above description is only a specific implementation of the present invention, but the protection scope of the present invention is not limited thereto. Any changes or substitutions that can be easily conceived by a technician familiar with the technical field within the technical scope disclosed by the present invention should be covered by the protection scope of the present invention.
Claims
1. A high-voltage connector for a Sanger sequencer, comprising a copper core (1), the copper core (1) being provided with a movable lock (2) that can move axially along the copper core (1), one end of the copper core (1) being provided with a recessed hole (3) that matches with a core of a high-voltage cable (8), and one end of the copper core (1) provided with the recessed hole (3) being sleeved with a base (4), characterized in that: It also includes an end cap (5), wherein the assembly end of the end cap (5) is interference-fitted inside the base body (4); The base body (4) is provided with a groove (6) which is interference-fitted with the assembly end of the end cap (5); The groove (6) is also used to fill with adhesive; During the process of interference fitting the end cap (5) inside the base (4), the end cap (5) squeezes the adhesive inside the groove (6) into the gap between the end cap (5) and the base (4), between the end cap (5) and the high-voltage cable (8) inserted in the recessed hole (3), between the copper core (1) and the end cap (5), between the copper core (1) and the base (4), and / or between the recessed hole (3) and the high-voltage cable (8).
2. A high-voltage connector for a Sanger sequencer according to claim 1, characterized in that: The adhesive is a high-pressure silicone adhesive or an epoxy resin adhesive.
3. A high-voltage connector for a Sanger sequencer according to claim 1, characterized in that: The assembly end of the end cap (5) matches with one end of the copper core (1) where the recessed hole (3) is provided.
4. A high-voltage connector for a Sanger sequencer according to claim 1, characterized in that: The clamping end of the end cap (5) is provided with a cavity adapted to the cable through it.
5. A high-voltage connector for a Sanger sequencer according to claim 4, characterized in that: The clamping end is a flexible component that can movably clamp the cable.
6. A high-voltage connector for a Sanger sequencer according to claim 5, characterized in that: The flexible component is rubber, a wing plate (7) is provided on the flexible component, and a movable gap is provided between the wing plate (7) and the end cap (5).
7. A high-voltage connector for a Sanger sequencer according to claim 4, characterized in that: The end cap (5) is integrally formed.