Biological material disinfection device

Abstract

The utility model provides a biological material disinfection device. The device comprises a case, a disinfection bin, a microwave generator, a vortex tube and the like, and the microwave generator is arranged in the microwave generator, and microwaves emitted by the microwave generator can fully disinfect the biological material, so that the sterile effect of the acellular biological material is ensured. The vortex tube is arranged, so that the temperature can be effectively controlled in the decellularized biological material disinfection process, and the decellularized biological material is prevented from being degraded or damaged due to too high temperature. The sterile filter is arranged, so that the sterile state of the decellularized biological material can be maintained. By arranging components such as a controller and a power supply in the case, automation of microwave disinfection can be realized. And the transparent box door is made of a polymer transparent material, so that the disinfection state of the acellular biological material can be observed in real time, and temperature-controllable automatic microwave disinfection is realized. The device is simple in structure, convenient to operate, free of chemicals inside, free of pollution, low in cost, long in service life and suitable for disinfection treatment of various decellularized biological materials.

Description

Technical Field

[0001] The utility model belongs to the technical field of biological materials and relates to a biological material disinfection device. Background Art

[0002] Decellularized biomaterials are allogeneic tissues that have been decellularized to remove antigenic components that can cause immune rejection, while completely retaining the three-dimensional spatial structure of the extracellular matrix and some growth factors that play an important role in cell differentiation, such as fibroblast growth factor 2, transforming growth factor β, vascular endothelial growth factor, etc. Decellularized matrix materials have attracted much attention in the field of tissue repair and regenerative medicine in recent years due to their good biocompatibility, degradability and tissue-induced regeneration ability.

[0003] At present, the commonly used disinfection methods for decellularized biomaterials include antibiotic disinfection, irradiation disinfection, and ethylene oxide disinfection. Antibiotic disinfection is the simplest method and can effectively inhibit the proliferation of bacteria; however, antibiotics have no obvious disinfection effect on viruses and fungi, and the possibility of reinfection after disinfection is relatively high. Irradiation disinfection has the characteristics of strong penetration and good disinfection effect, but the irradiation dose and irradiation time are difficult to control, which can easily cause the breakage of macromolecular chains and discoloration of biomaterials, thereby causing degradation or hardening of decellularized biomaterials. Ethylene oxide disinfection is a commonly used disinfection method in clinical practice, but ethylene oxide disinfection is prone to produce highly toxic products in the form of chlorides as the main form, and they exist for a long time, which is not conducive to the patient's transplantation.

[0004] Therefore, the above-mentioned several disinfection methods are not able to disinfect the decellularized biomaterials well. Utility Model Content

[0005] The utility model aims to provide a biological material disinfection device to solve the problems of incomplete disinfection, large toxic residue and easy degradation of existing decellularized biological materials.

[0006] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0007] The utility model provides a biological material disinfection device, comprising a chassis and a disinfection chamber located inside the chassis, wherein a microwave generator and a vortex tube are respectively arranged on both sides of the disinfection chamber; a hot air outlet of the vortex tube is connected to the outside of the chassis through a first control valve, and a cold air outlet of the vortex tube is connected to the disinfection chamber; the vortex tube is also connected to a compressed air inlet pipe located outside the chassis through a second control valve.

[0008] Preferably, a sterile filter is provided at the cold air outlet, and the sterile filter is located inside the disinfection chamber.

[0009] Preferably, a gas dispersion plate is further provided on the inner wall of the disinfection chamber, and the gas dispersion plate covers the sterile filter and faces the interior of the disinfection chamber.

[0010] Preferably, a plurality of gas dispersion holes are provided on the gas dispersion plate.

[0011] Preferably, a temperature sensor is provided inside the disinfection chamber.

[0012] Preferably, a side of the chassis where the microwave generator is disposed is also provided with an electrically connected power supply and a controller, and the controller and the power supply are electrically connected to the microwave generator, the first control valve and the second control valve, respectively.

[0013] Preferably, a display screen is provided outside the chassis, and the display screen is electrically connected to the power supply.

[0014] Preferably, a transparent door is further provided on the outside of the chassis, and the transparent door is connected to the chassis via a hinge.

[0015] Preferably, a button is also provided on the outside of the chassis, and the button controls the opening and closing of the transparent door.

[0016] The utility model has the following beneficial effects:

[0017] (1) The microwave generator is installed inside the microwave generator. The microwaves emitted by the microwave generator can fully disinfect the biological materials and ensure the sterility of the decellularized biological materials.

[0018] (2) The setting of the vortex tube can ensure effective temperature control during the sterilization process of the decellularized biomaterials, avoiding degradation or damage of the decellularized biomaterials due to excessive temperature. The setting of the sterile filter can maintain the sterility of the decellularized biomaterials.

[0019] (3) The settings of the controller, power supply and other components in the chassis can realize the automation of microwave disinfection. The transparent door is made of transparent polymer material, which can observe the disinfection status of decellularized biological materials in real time and realize temperature-controlled automated microwave disinfection.

[0020] (4) The device has a simple structure, is easy to operate, contains no chemicals or pollution, has low cost, and has a long lifespan. It can be used for the disinfection of various decellularized biomaterials. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 A schematic diagram of the three-dimensional structure of a biological material disinfection device provided in an embodiment of the present application;

[0022] Figure 2 A transverse cross-sectional view of a biological material disinfection device provided in an embodiment of the present application;

[0023] Figure 3 A longitudinal cross-sectional view of a biological material disinfection device provided in an embodiment of the present application;

[0024] Symbols represent:

[0025] 1-chassis, 2-compressed air inlet pipe, 3-second control valve, 4-hot air outlet, 5-first control valve, 6-cold air outlet, 7-sterile filter, 8-gas dispersion plate, 9-transparent door, 10-hinge, 11-button, 12-display screen, 13-temperature sensor, 14-power supply, 15-controller, 16-microwave generator, 17-vortex tube, 18-disinfection chamber. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0027] Please refer to the attached Figure 1-3 , attached Figure 1-3 The three-dimensional structure diagram, transverse cross-sectional diagram and longitudinal cross-sectional diagram of the biomaterial disinfection device provided in the embodiment of the present application are respectively shown. Figure 1-3 It can be seen that the biological material disinfection device provided in the embodiment of the present application includes a chassis 1 and a disinfection chamber 18 located inside the chassis 1, wherein the chassis 1 is the external shell structure of the biological material disinfection device, and the disinfection chamber 18 is used to place the biological material to be disinfected. A transparent door 9 is provided on the outside of the chassis 1, and the transparent door 9 is connected to the chassis 1 through a hinge 10. In addition, a button 11 is also provided on the outside of the chassis 1, and the button 11 can control the opening and closing of the transparent door 9. Thus, when it is necessary to take and place the biological material, the transparent door 9 can be opened by pressing the button 11. In the embodiment of the present application, the transparent door 9 is made of a polymer transparent material so that the disinfection of the biological material in the disinfection chamber 18 can be visually observed.

[0028] A microwave generator 16 and a vortex tube 17 are respectively provided on both sides of the disinfection chamber 18, wherein a microwave generator is arranged inside the microwave generator 16, and the microwaves emitted by the microwave generator can disinfect the biological material to ensure the sterility of the decellularized biological material; the vortex tube 17 is used to effectively control the temperature in the disinfection chamber 18 to ensure that the decellularized biological material is not damaged during the microwave disinfection process.

[0029] Specifically, the vortex tube 17 is a tubular structure, with openings at both ends and the top, and the openings at both ends are hot air outlets 4 and cold air outlets 6, respectively. Figure 2 As shown. The hot air outlet 4 is connected to the outside of the chassis 1 through the first control valve 5, so that the hot air generated in the vortex tube 17 is discharged to the outside of the chassis 1 through the hot air outlet 4. The cold air outlet 6 is connected to the disinfection chamber 18, whereby the disinfection chamber 18 is connected to the outside of the chassis 1 through the vortex tube 17 and the first control valve 5. In addition, the opening at the top of the vortex tube 17 is connected to the compressed air inlet pipe 2 located outside the chassis 1 through the second control valve 3, and the compressed air inlet pipe 2 is connected to the external compressor. Thus, through the compressed air inlet pipe 2, the external compressor can discharge the compressed air into the vortex tube 17.

[0030] After the compressed air is discharged into the vortex tube 17 through the compressed air inlet pipe 2 and the second control valve 3, the compressed air rotates at a speed of up to one million revolutions per minute and flows to the hot air outlet 4 of the vortex tube 17. Part of the compressed air flows out through the first control valve 5 and the hot air outlet 4; after the other part of the compressed air is blocked, it rotates in the opposite direction at the same speed in the inner circle of the original air flow and flows to the cold air outlet 6 of the vortex tube 17. In this process, the two air flows undergo heat exchange, the inner ring air flow becomes very cold, and is discharged into the disinfection chamber 18 from the cold air outlet 6 of the vortex tube 17; the outer ring air flow becomes very hot and is discharged from the hot air outlet 4 of the vortex tube 17. As a result, low-temperature gas can be generated through the vortex tube 17, and the temperature and flow rate of the low-temperature gas are adjusted and controlled by the first control valve 5. When the opening of the first control valve 5 is larger, the proportion of hot air flow flowing out of the hot air outlet 4 is higher, and the temperature of the cold air flow generated at the cold air outlet 6 of the vortex tube 17 is lower, and the flow rate is reduced accordingly.

[0031] Furthermore, in order to control the first control valve 5, the second control valve 3, the microwave generator 16, etc., a power supply 14 and a controller 15 are also electrically connected on one side of the cabinet 1 where the microwave generator 16 is provided, and the power supply 14 and the controller 15 are electrically connected to the first control valve 5, the second control valve 3, and the microwave generator 16, respectively, so as to control the microwave disinfection time and temperature of the microwave generator 16 through the controller 15; and at the same time, control the opening of the first control valve 5 and the second control valve 3, thereby controlling the disinfection temperature in the disinfection chamber 18. In addition, the power supply 14 is also electrically connected to the button 11, so as to control the opening and closing of the transparent door 9 through the button 11.

[0032] Furthermore, a display screen 12 is provided outside the chassis 1, and the display screen 12 is electrically connected to a power supply 14. The microwave disinfection time and temperature can be observed in real time through the display screen 12.

[0033] In the embodiment of the present application, a sterile filter 7 is provided at the cold air outlet 6, and the sterile filter 7 is located inside the disinfection chamber 18. The cold air generated by the vortex tube 17 is sprayed on the sterile filter 7 through the cold air outlet 6, and after the bacteria are filtered out by the sterile filter 7, it enters the disinfection chamber 18 to ensure that the gas environment in the disinfection chamber 18 is a sterile environment. Furthermore, in order to ensure that the cold air is effectively dispersed in the disinfection chamber 18, a gas dispersion plate 8 is also provided on the inner wall of the disinfection chamber 18, and the gas dispersion plate 8 covers the sterile filter 7 and faces the inside of the disinfection chamber 18. In addition, a plurality of gas dispersion holes are provided on the gas dispersion plate 8 to facilitate gas dispersion. In order to monitor the temperature during the disinfection process of the decellularized biomaterial in real time, a temperature sensor 13 is provided inside the disinfection chamber 18, and the temperature sensor 13 is electrically connected to the controller 15, so that the controller 15 can adjust the opening of the first control valve 5, thereby adjusting the internal temperature of the disinfection chamber 18.

[0034] In the biomaterial disinfection device provided in the embodiment of the present application, the microwaves emitted by the microwave generator 16 can disinfect the biomaterial and ensure the sterility of the decellularized biomaterial. The setting of the vortex tube 17 can ensure effective temperature control during the disinfection of the decellularized biomaterial to avoid degradation or damage to the decellularized biomaterial due to excessive temperature. The setting of the sterile filter 7 can maintain the sterility of the decellularized biomaterial. The biomaterial disinfection device has a simple structure, simple control, and convenient operation. It is free of chemicals and pollution inside, has low cost, and has a long service life. It can be applied to the disinfection of various decellularized biomaterials.

[0035] The above description is only the preferred embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A biological material disinfection device, characterized in that: The invention comprises a case (1) and a disinfection chamber (18) located inside the case (1), wherein a microwave generator (16) and a vortex tube (17) are respectively provided on both sides of the disinfection chamber (18); a hot air outlet (4) of the vortex tube (17) is connected to the outside of the case (1) via a first control valve (5), and a cold air outlet (6) of the vortex tube (17) is connected to the disinfection chamber (18); and the vortex tube (17) is also connected to a compressed air inlet pipe (2) located outside the case (1) via a second control valve (3).

2. The biological material disinfection device according to claim 1, characterized in that: A sterile filter (7) is provided at the cold air outlet (6), and the sterile filter (7) is located inside the disinfection chamber (18).

3. The biological material disinfection device according to claim 2, characterized in that: A gas dispersion plate (8) is also provided on the inner wall of the disinfection chamber (18), wherein the gas dispersion plate (8) covers the sterile filter (7) and faces the interior of the disinfection chamber (18).

4. The biological material disinfection device according to claim 3, characterized in that: The gas dispersion plate (8) is provided with a plurality of gas dispersion holes.

5. The biological material disinfection device according to claim 1, characterized in that: A temperature sensor (13) is provided inside the disinfection chamber (18).

6. The biological material disinfection device according to claim 1, characterized in that: A side of the cabinet (1) on which the microwave generator (16) is disposed is also provided with an electrically connected power supply (14) and a controller (15); the controller (15) and the power supply (14) are respectively electrically connected to the microwave generator (16), the first control valve (5), and the second control valve (3).

7. The biological material disinfection device according to claim 6, characterized in that: A display screen (12) is provided outside the chassis (1), and the display screen (12) is electrically connected to the power supply (14).

8. The biological material disinfection device according to claim 1, characterized in that: A transparent door (9) is also provided on the outside of the chassis (1), and the transparent door (9) is connected to the chassis (1) via a hinge (10).

9. The biological material disinfection device according to claim 8, characterized in that: A button (11) is also provided on the outside of the cabinet (1), and the button (11) controls the opening and closing of the transparent cabinet door (9).

Images