ACI collection plate sample transfer device

Abstract

The utility model discloses an ACI collecting plate sample transfer device which comprises a collecting cup and a plurality of hooks used for hanging a collecting plate in the collecting cup, the cup opening of the collecting cup expands outwards to form an annular edge, and the top ends of the hooks are detachably connected with the annular edge. The collecting plate is horizontally suspended at a certain depth in the collecting cup through the hooks, all parts of the surface of the collecting plate are in sufficient contact with a solvent in the shaking process, so that a sample on the collecting plate is sufficiently eluted, and the depth of the collecting plate in the collecting cup can be adjusted by replacing the hooks with different lengths to adapt to different solvent amounts.

Description

Technical Field

[0001] The utility model relates to an experimental sampling device, in particular to an ACI collecting plate sample transfer device. Background Art

[0002] When analyzing drugs, it is necessary to transfer samples from the collection plate and / or stage of the ACI (Andersen Cascade Impactor) for analysis. During this process, the sample transfer must be thorough, otherwise it will affect the accuracy of the analysis. In order to ensure effective sample transfer, glycerol, silicone oil or other suitable liquids can be dissolved in a volatile solution and then coated on the surface of the collection plate (Chinese Pharmacopoeia 2020 Edition Part IV General Rules 0951).

[0003] The invention patent application with the publication number of CN 108421762 A discloses a drug cleaning and recovery system suitable for an ACI particle impactor, wherein the device for transferring samples comprises a sealing component and a clamping component, wherein the clamping component comprises a small plate cover and a small plate seat, wherein a first groove is provided inside the small plate seat, wherein a diluent and the ACI component are placed in the first groove, wherein the small plate cover is sealed and covered on the small plate seat, wherein the clamping component comprises a large plate seat and a large plate cover connected to each other, wherein a second groove for accommodating the small plate seat is provided on the large plate seat, wherein a third groove for positioning the small plate cover is provided on the large plate cover, wherein when the large plate seat and the large plate cover are closed, the small plate cover and the small plate seat are pressed and sealed. The device is suitable for co-eluting the drugs on the ACI particle impactor stage seat and the collecting plate when the amount of solvent is large, but is not suitable for the working condition of using a small amount of solvent to transfer the samples on the collecting plate separately. Utility Model Content

[0004] Purpose of the utility model: The purpose of the utility model is to provide an ACI collection plate sample transfer device that can fully transfer samples.

[0005] Technical solution: The utility model discloses an ACI collection plate sample transfer device, comprising a collection cup and a plurality of hooks for suspending the collection plate in the collection cup. The mouth of the collection cup expands outward to form an annular edge, and the top end of the hook is detachably connected to the annular edge.

[0006] The annular edge allows the collection cup to be connected to the shaking device. The hook suspends the collection plate horizontally at a certain depth inside the collection cup. The contact area between the hook and the collection plate is small. During the shaking process, the collection plate can move relative to the hook, and its surface is in contact with sufficient solvent everywhere, so the sample is fully eluted. By replacing hooks of different lengths, the depth of the collection plate in the collection cup can be adjusted to adapt to different solvent volumes.

[0007] Preferably, the annular edge is evenly provided with insertion holes, the top of the hook is provided with a latch, and the hook and the annular edge are detachably connected via the latch and the insertion holes.

[0008] Preferably, the hook is made of polytetrafluoroethylene material to facilitate sample transfer. The number of the hooks is not less than 3, and more than 3 hooks can ensure that the collection plate is placed horizontally.

[0009] Preferably, it also includes a support plate for connecting the collection cup and the shaking bed device, wherein the support plate is provided with a plurality of through holes for the collection cup body to pass through. The collection cup can be hung on the support plate by an annular edge and fixed relative to the support plate.

[0010] Preferably, the outer periphery of the through hole of the support plate is provided with positioning holes that are consistent with the number and arrangement of the sockets, and when the latch is inserted into the annular edge socket, it is also inserted into the positioning hole to complete the locking of the collection cup and the support plate.

[0011] Preferably, the annular edge is evenly provided with latches, the top of the hook is provided with a socket, and the hook and the annular edge are detachably connected via the socket and the latch.

[0012] Preferably, the bottom end of the hook is arranged in a groove for placing the edge of the collecting plate. The collecting plate can support the collecting plate and place the collecting plate and the collecting cup at the same time or the hook is fixedly connected, so as to facilitate the full transfer of the sample on the collecting plate.

[0013] Preferably, the two side walls of the groove are arc-shaped. The arc-shaped side walls increase the clamping stability of the collection plate and reduce the number of hooks. However, the arc-shaped side walls increase the contact area between the collection plate and the hooks, which is not conducive to sample transfer. Therefore, the width of the two ends of the arc-shaped side arms gradually decreases to ensure support strength while reducing contact.

[0014] Beneficial effects: Compared with the prior art, the utility model has the following advantages: 1. Full sample transfer: During the shaking process, all parts of the collection plate can be fully in contact with the diluent, and the transfer is thorough; 2. Light weight; 3. Simple structure and easy to assemble; 4. The height of the collection plate in the collection cup can be flexibly adjusted to meet the elution requirements of different amounts of diluent / elution solvent; 5. The hook is made of polytetrafluoroethylene, which reduces the friction between the collection plate and the stainless steel collection cup, and avoids scratches on the collection plate that affect the overall performance of the device; 6. The drugs on multiple collection plates are recovered at the same time with the same shaking frequency and cleaning time, which reduces manual operation errors and improves the reproducibility of experimental data. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 This is a front view of the structure of the first embodiment of the utility model.

[0016] Figure 2It is a schematic diagram of the three-dimensional structure of the first embodiment of the utility model.

[0017] Figure 3 It is a schematic diagram of the three-dimensional structure of the second embodiment of the utility model.

[0018] Figure 4 This is a schematic diagram of the hook structure of the first embodiment of the utility model.

[0019] Figure 5 This is a schematic diagram of the hook structure of the third embodiment of the utility model.

[0020] Figure 6 This is a schematic diagram of the collecting cup structure of the first embodiment of the utility model. DETAILED DESCRIPTION

[0021] The technical solution of the utility model is further described below in conjunction with the accompanying drawings.

[0022] Example 1: Figure 6 As shown, it is a schematic diagram of the structure of the collecting cup 2 of the utility model. The cup body of the collecting cup 2 is a straight cylinder. The cup mouth of the collecting cup 2 expands horizontally outward to form an annular edge. The annular edge is evenly provided with plug holes 21. The plug holes 21 can be blind holes or through holes.

[0023] like Figure 4 As shown, it is a schematic diagram of the structure of the hook 3 of the utility model. The cross section of the hook 3 is approximately Z-shaped, the top is horizontal, the free end is bent downward to form a latch 31, and the bottom is provided with clamping claws arranged up and down, and a groove 32 is formed between the two clamping claws. The height of the groove is greater than the thickness of the collecting plate 4 (to be confirmed), ensuring the clamping of the collecting plate 4, while preventing the collecting plate 4 from being fixed. In this way, the collecting plate 4 can move relative to the hook during the shaking process, and can be fully contacted with the diluent at all places. The hook 3 is made of polytetrafluoroethylene.

[0024] like Figure 2 As shown, it is a schematic diagram of the overall assembly state of the utility model, the support plate 1 is a long strip, and through holes are evenly opened on the support plate 1, and the diameter of the through holes is consistent with the outer diameter of the collection cup 2. Positioning holes (not shown) that are consistent in number and distribution with the insertion holes 21 can be evenly opened on the outer periphery of the through holes.

[0025] like Figure 1 and Figure 2As shown, when in use, the collection plate 4 (to be confirmed) taken out from the ACI is placed by its edge into the bottom groove 32 of the hook 3, and then the top pin 31 of the hook 3 is aligned with the socket 21 and pressed to complete the assembly of the device. Alternatively, the socket 21 and the positioning hole are aligned and then the pin 31 is pressed to complete the relative fixation of the collection cup 2 and the support plate 1. Finally, a certain volume of diluent is added to the collection cup 2, and the support plate 1 is fixed to the shaking device to start the sample transfer on the collection plate 1.

[0026] Embodiment 2: As a variation of Embodiment 1, Figure 3 As shown, a latch 21 is provided on the annular edge of the collecting cup 2, and a through hole 31 is provided on the top of the hook 3. The hook 3 is inserted into the latch 21 to complete the relative fixation of the hook and the collecting cup.

[0027] Embodiment 3: As a variation of Embodiment 2, Figure 5 As shown, the clamping claw at the bottom of the hook 3 is an arc-shaped clamping claw. By setting the clamping claw in an arc shape, the number of hooks 3 can be reduced. For example, in Example 1, only when the number of hooks is 3 can the collecting plate 4 be kept horizontal. When the hooks of this embodiment are used, only two are used, and the plug hole at the top of the hook can also be replaced with a pin. The width of the clamping claw gradually decreases from the middle to the two ends.

Claims

1. An ACI collection plate sample transfer device, characterized in that: It comprises a collection cup (2) and a plurality of hooks (3) for suspending a collection plate in the collection cup. The mouth of the collection cup (2) expands outwards to form an annular edge. The top end of the hook (3) is detachably connected to the annular edge.

2. The ACI collection plate sample transfer device according to claim 1, characterized in that: The annular edge is evenly provided with insertion holes (21), the top end of the hook is provided with a latch (31), and the hook and the annular edge are detachably connected via the latch and the insertion holes.

3. The ACI collection plate sample transfer device according to claim 1, characterized in that: The hook (3) is made of polytetrafluoroethylene material.

4. The ACI collection plate sample transfer device according to claim 2, characterized in that: It also comprises a support plate (1) for connecting the collection cup and the shaking bed device, wherein the support plate is provided with a plurality of through holes for the cup body of the collection cup (2) to pass through.

5. The ACI collection plate sample transfer device according to claim 4, characterized in that: The outer periphery of the through hole of the support plate (1) is provided with positioning holes whose number and arrangement are consistent with those of the insertion holes (21).

6. The ACI collection plate sample transfer device according to claim 1, characterized in that: The annular edge is evenly provided with latches, the top of the hook is provided with a socket, and the hook and the annular edge are detachably connected via the socket and the latch.

7. The ACI collection plate sample transfer device according to claim 1, characterized in that: The bottom end of the hook is arranged in a groove for placing the edge of the collecting plate.

8. The ACI collection plate sample transfer device according to claim 7, characterized in that: The two side walls of the groove are arc-shaped, and the width of the two ends of the side walls gradually decreases.

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