A crystallization kettle for drug preparation intermediates

Abstract

The utility model relates to a crystallization kettle for preparing intermediates of drugs, comprising a tank body, a top cover is arranged on the top of the tank body, a supporting foot is arranged on the outer side of the bottom of the tank body, a discharge pipe is arranged in the middle of the bottom of the tank body, a liquid inlet and a feed inlet are arranged on both sides of the top of the top cover respectively, a stirring component is arranged in the middle of the top of the top cover, the stirring component comprises a supporting platform, a first driving mechanism, a stirring rod and stirring blades, a cooling component is arranged on the outer surface of the tank body, and the cooling component comprises an outer cylinder, a water inlet pipe and a drain pipe; the utility model can better dock and fix with the stirring rod through the arranged docking plate and mounting block, and cooperates with the arranged second driving mechanism and threaded rod and threaded groove, so that when stirring is performed, the scraper can be controlled to retract backwards, thereby preventing the scraper from contacting with the inner wall of the tank body during stirring, reducing the wear of the scraper and the tank body, and also reducing the load on the first driving mechanism.

Description

Technical Field

[0001] The utility model relates to the technical field of crystallization kettles, in particular to a crystallization kettle used for preparing intermediates of medicines. Background Art

[0002] When preparing drug intermediates, a crystallization kettle is generally required, and the drug is processed and prepared through the processes of heating, cooling, stirring and mixing in the crystallization kettle.

[0003] At present, most of the crystallization kettles are driven by a driving mechanism to drive a stirring rod and a stirring blade to stir and mix the drug when in use. However, since the inner wall of the crystallization kettle is not easy to clean, most of the crystallization kettles are equipped with a cleaning structure on the internal stirring rod. As the stirring rod rotates, the inner wall of the crystallization kettle is scraped and cleaned. However, since the crystallization kettle is used for stirring and mixing most of the time, the existing cleaning structure lacks an adjusting part, resulting in the cleaning structure scraping the inner wall while stirring when cleaning is not needed, which not only increases the wear on the scraper, but also increases the load on the driving mechanism. Therefore, it is necessary to design a crystallization kettle for drug preparation intermediates with a freely adjustable cleaning structure to solve the above problems. Utility Model Content

[0004] In view of the deficiencies in the prior art, the utility model provides a crystallization kettle for preparing drug intermediates, which is used to solve the problems raised by the above-mentioned background technology.

[0005] The utility model discloses a crystallization kettle for preparing intermediates of drugs, comprising a tank body, a top cover is arranged on the top of the tank body, a supporting foot is arranged on the outer side of the bottom of the tank body, a discharge pipe is arranged in the middle of the bottom of the tank body, a liquid inlet and a feed inlet are arranged on both sides of the top of the top cover respectively, a stirring component is arranged in the middle of the top of the top cover, the stirring component comprises a supporting platform, a first driving mechanism, a stirring rod and stirring blades, a cooling component is arranged on the outer surface of the tank body, the cooling component comprises an outer cylinder, a water inlet pipe and a drain pipe; a cleaning component is arranged in the middle of the stirring rod, and the cleaning component comprises a scraper, a sliding rod, a sliding sleeve, a docking plate, a mounting block, a power block, a mounting cavity, a second driving mechanism, a threaded rod and a threaded groove.

[0006] As a further improvement of the utility model, the outer cylinder is arranged on the outer surface of the tank body, a cooling cavity is opened inside the outer cylinder, the water inlet pipe is arranged on the left side of the outer cylinder near the top end, and the drain pipe is arranged on the right side of the outer cylinder near the bottom end, and the water inlet pipe and the drain pipe are both connected to the cooling cavity.

[0007] As a further improvement of the present invention, the support platform is arranged in the middle of the top end of the top cover, the first driving mechanism is installed on the top end of the support platform, and the support platform is designed in a truncated cone shape.

[0008] As a further improvement of the present invention, the top end of the stirring rod passes through the top cover and the support platform and is connected to the output shaft of the first drive mechanism, the other end of the stirring rod extends to the inner cavity of the tank body near the bottom end, and the stirring blade is installed on the outer surface of the stirring rod near the bottom end.

[0009] As a further improvement of the present invention, the middle section of the stirring rod is cut into two sections, and the ends of the two sections of the stirring rod that are close to each other are connected to the mounting block through a docking plate.

[0010] As a further improvement of the present invention, the installation cavity is opened inside the installation block, and the power block and the second driving mechanism are both installed inside the installation cavity and electrically connected.

[0011] As a further improvement of the utility model, there are two sliding sleeves and they are respectively arranged on both sides of the mounting block, the sliding rod is slidably connected to the end of the sliding sleeve away from the mounting block, the scraper is installed at the end of the sliding rod away from the sliding sleeve, the threaded rod is connected to the output rods at both ends of the second driving mechanism, and the threaded groove is opened on the side of the sliding rod close to the threaded rod and is threadedly connected to the threaded rod.

[0012] Compared with the prior art, the beneficial effects of the utility model are as follows:

[0013] 1. The utility model can better dock and fix with the stirring rod through the provided docking plate and the mounting block, and cooperate with the provided second driving mechanism, the threaded rod and the threaded groove, so that when stirring, the scraper can be controlled to retract backward, thereby preventing the scraper from contacting the inner wall of the tank body during stirring, reducing the wear of the scraper and the tank body, and also reducing the load on the first driving mechanism;

[0014] 2. At the same time, the provided sliding rod and sliding sleeve are used in conjunction with the mounting cavity and the power block, so that the second driving mechanism drives the scraper to move more stably, and the second driving mechanism can operate better in conjunction with the power block and the mounting cavity. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The drawings described herein are used to provide a further understanding of the present application and constitute a part of the present application. The illustrative embodiments of the present application and their descriptions are used to explain the present application and do not constitute an improper limitation on the present application. In the drawings:

[0016] Figure 1 It is a schematic diagram of the overall three-dimensional structure of the utility model;

[0017] Figure 2 This is a schematic diagram of the overall front view and cross-sectional structure of the utility model;

[0018] Figure 3 This is a schematic diagram of the three-dimensional structure of the installation block of the utility model;

[0019] Figure 4 For this utility model Figure 2 A is an enlarged structural diagram of FIG.

[0020] In the figure: 01, tank body; 011, supporting foot; 012, discharge pipe; 013, top cover; 014, liquid inlet; 015, feed port; 02, outer cylinder; 021, water inlet pipe; 022, discharge pipe; 03, supporting platform; 031, first driving mechanism; 032, stirring rod; 033, stirring blade; 04, scraper; 041, sliding rod; 042, sliding sleeve; 05, docking plate; 051, mounting block; 052, power block; 053, mounting cavity; 054, second driving mechanism; 055, threaded rod; 056, threaded groove. DETAILED DESCRIPTION

[0021] The following will disclose multiple embodiments of the utility model with diagrams. For the purpose of clear description, many physical details will be described together in the following description. However, it should be understood that these physical details should not be used to limit the utility model. In other words, in some embodiments of the utility model, these physical details are not necessary. In addition, for the purpose of simplifying the diagram, some conventional structures and components will be depicted in a simple schematic manner in the diagram.

[0022] In addition, the terms "horizontal", "vertical", "overhanging" and the like do not mean that the components are required to be absolutely horizontal or overhanging, but can be slightly tilted. For example, "horizontal" only means that its direction is more horizontal than "vertical", and does not mean that the structure must be completely horizontal, but can be slightly tilted.

[0023] In the description of this technology, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in this technology can be understood according to specific circumstances.

[0024] In addition, the technical solutions between the various embodiments can be combined with each other, but it must be based on the fact that ordinary technicians in the field can implement it. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such combination of technical solutions does not exist and is not within the scope of protection required by the present utility model.

[0025] See also Figure 1-4The utility model includes a tank body 01, a top cover 013 is arranged on the top of the tank body 01, a supporting foot 011 is arranged on the outer side of the bottom of the tank body 01, a discharge pipe 012 is arranged in the middle of the bottom of the tank body 01, a liquid inlet 014 and a feed inlet 015 are arranged on both sides of the top of the top cover 013 respectively, a stirring assembly is arranged in the middle of the top of the top cover 013, the stirring assembly includes a support platform 03, a first driving mechanism 031, a stirring rod 032 and a stirring blade 033, a cooling assembly is arranged on the outer surface of the tank body 01, the cooling assembly includes an outer cylinder 02, a water inlet pipe 021 and a drain pipe 022; a cleaning assembly is arranged in the middle of the stirring rod 032, and the cleaning assembly includes a scraper 04, a sliding rod 041, a sliding sleeve 042, a docking plate 05, a mounting block 051, a power block 052, a mounting cavity 053, a second driving mechanism 054, a threaded rod 055 and a threaded groove 056.

[0026] See also Figure 1 and Figure 2 In this embodiment, in order to better perform cooling and heating treatment on the inside of the tank body 01, the outer cylinder body 02 is arranged on the outer surface of the tank body 01, and a cooling cavity is opened inside the outer cylinder body 02. The water inlet pipe 021 is arranged on the left side of the outer cylinder body 02 near the top, and the drain pipe 022 is arranged on the right side of the outer cylinder body 02 near the bottom, and both the water inlet pipe 021 and the drain pipe 022 are connected to the cooling cavity.

[0027] When the inside of the tank body 01 needs to be cooled or heated, cooling water or hot steam is injected from the water inlet pipe 021 into the cooling cavity inside the outer cylinder body 02 to cool or heat the inside of the tank body 01 through heat conduction, and finally the cooling water or steam can be discharged from the drain pipe 022.

[0028] See also Figure 1 and Figure 2 It should be noted that, in order to better stir and mix the medicine, the support platform 03 is arranged at the middle of the top of the top cover 013, and the first driving mechanism 031 is installed at the top of the support platform 03, and the support platform 03 is designed in a truncated cone shape;

[0029] The top end of the stirring rod 032 passes through the top cover 013 and the support platform 03 and is connected to the output shaft of the first driving mechanism 031. The other end of the stirring rod 032 extends to the inner cavity of the tank body 01 near the bottom end. The stirring blade 033 is installed on the outer surface of the stirring rod 032 near the bottom end. The first driving mechanism 031 is a stepping motor and its model is: 35BYG101.

[0030] When stirring is required, the material and the mixed liquid are first poured into the tank body 01 from the material feed port 015 and the liquid inlet 014, and then the first driving mechanism 031 is started to drive the stirring rod 032 and the stirring blade 033 to stir and mix the material.

[0031] See also Figure 3 and Figure 4 Specifically, in order to better control the distance between the scraper 04 and the inner wall of the tank body 01, thereby reducing the wear on the scraper 04 and the inner wall of the tank body 01, the middle section of the stirring rod 032 is cut into two sections, and the ends of the two sections of the stirring rod 032 that are close to each other are connected to the mounting block 051 through the docking plate 05;

[0032] The installation cavity 053 is opened inside the installation block 051, and the power supply block 052 and the second driving mechanism 054 are both installed inside the installation cavity 053 and electrically connected;

[0033] There are two sliding sleeves 042 and they are respectively arranged on both sides of the mounting block 051. The sliding rod 041 is slidably connected to the end of the sliding sleeve 042 away from the mounting block 051. The scraper 04 is installed on the end of the sliding rod 041 away from the sliding sleeve 042. The threaded rod 055 is connected to the output rods at both ends of the second driving mechanism 054. The threaded groove 056 is opened on the side of the sliding rod 041 close to the threaded rod 055 and is threadedly connected to the threaded rod 055. The second driving mechanism 054 is a double-headed motor and its model is: WK-1625-02.

[0034] When stirring is required, the second driving mechanism 054 is controlled to rotate in the opposite direction, thereby driving the threaded rod 055 to rotate, and cooperating with the threaded groove 056 to drive the slide rod 041 to retract into the sleeve 042, thereby driving the scraper 04 away from the inner wall of the tank body 01. When cleaning is required, the second driving mechanism 054 is controlled to rotate forward, thereby driving the slide rod 041 to move to the side away from the sleeve 042, so that the scraper 04 fits the inner wall of the tank body 01, and then the first driving mechanism 031 is started to drive the stirring rod 032 to rotate, thereby driving the scraper 04 to scrape and clean the inner wall of the tank body 01.

[0035] The above description is only an embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the scope of the claims of the present invention.

Claims

1. A crystallization kettle for preparing drug intermediates, comprising a tank body (01), characterized in that: The top of the tank body (01) is provided with a top cover (013), the outer side of the bottom of the tank body (01) is provided with a supporting foot (011), the middle part of the bottom of the tank body (01) is provided with a discharge pipe (012), the two sides of the top of the top cover (013) are respectively provided with a liquid inlet (014) and a feed inlet (015), the middle part of the top of the top cover (013) is provided with a stirring assembly, the stirring assembly comprises a supporting platform (03), a first driving mechanism (031), a stirring rod (032) and a stirring blade (033), and the outer surface of the tank body (01) is provided with a cooling assembly, the cooling assembly comprises an outer cylinder (02), a water inlet pipe (021) and a drain pipe (022); A cleaning assembly is arranged in the middle of the stirring rod (032), and the cleaning assembly comprises a scraper (04), a sliding rod (041), a sliding sleeve (042), a docking plate (05), a mounting block (051), a power block (052), a mounting cavity (053), a second driving mechanism (054), a threaded rod (055) and a threaded groove (056).

2. A crystallization kettle for preparing a drug intermediate according to claim 1, characterized in that: The outer cylinder (02) is arranged on the outer surface of the tank body (01), and a cooling cavity is provided inside the outer cylinder (02). The water inlet pipe (021) is arranged on the left side of the outer cylinder (02) near the top end, and the drainage pipe (022) is arranged on the right side of the outer cylinder (02) near the bottom end. Both the water inlet pipe (021) and the drainage pipe (022) are connected to the cooling cavity.

3. A crystallization kettle for preparing a drug intermediate according to claim 1, characterized in that: The support platform (03) is arranged at the middle of the top end of the top cover (013), the first driving mechanism (031) is installed at the top end of the support platform (03), and the support platform (03) is designed in a truncated cone shape.

4. A crystallization kettle for preparing a drug intermediate according to claim 1, characterized in that: The top end of the stirring rod (032) passes through the top cover (013) and the support platform (03) and is connected to the output shaft of the first driving mechanism (031); the other end of the stirring rod (032) extends to a position near the bottom end of the inner cavity of the tank body (01); and the stirring blade (033) is installed on the outer surface of the stirring rod (032) near the bottom end.

5. A crystallization kettle for preparing a drug intermediate according to claim 1, characterized in that: The middle section of the stirring rod (032) is cut into two sections, and the ends of the two sections of the stirring rod (032) that are close to each other are connected to the mounting block (051) through a docking plate (05).

6. A crystallization kettle for preparing a drug intermediate according to claim 1, characterized in that: The installation cavity (053) is opened inside the installation block (051), and the power supply block (052) and the second driving mechanism (054) are both installed inside the installation cavity (053) and are electrically connected.

7. A crystallization kettle for preparing a drug intermediate according to claim 1, characterized in that: There are two sliding sleeves (042) and they are respectively arranged on both sides of the mounting block (051); the sliding rod (041) is slidably connected to one end of the sliding sleeve (042) away from the mounting block (051); the scraper (04) is installed on one end of the sliding rod (041) away from the sliding sleeve (042); the threaded rod (055) is connected to the output rods at both ends of the second driving mechanism (054); and the threaded groove (056) is opened on one side of the sliding rod (041) close to the threaded rod (055) and is threadedly connected to the threaded rod (055).

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