Drug sterilization system

Through the circulating high-temperature airflow technology, the problems of water stain residues and bacterial contamination during the sterilization of drug powder are solved, and efficient synchronous sterilization of drug powder is achieved, and the quality of drug is improved.

CN222752334UActive Publication Date: 2025-04-15ZIBO HUIBANG ENVIRONMENTAL ENG CO LTD
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Patent Information

Application Number
CN202520460606.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-17
Publication Date
2025-04-15
Estimated Expiration
2035-03-17

AI Technical Summary

Technical Problem

The prior art has problems of water stain residues and bacterial contamination during the sterilization process of drug powder, especially when the drug powder is transported, it is easy to be contaminated by bacteria, resulting in poor quality of subsequent drugs.

Method used

Replace high-temperature airflow for sterilization, and the circulating contact between the drug powder and the high-temperature airflow is achieved through the Venturi jet pump and the cyclic flow assembly to ensure that the drug powder is fully sterilized at high temperatures and reduce water stain residues.

Benefits of technology

Synchronous high-temperature sterilization of the inside of the tank equipment and the drug powder is achieved, avoiding water stain residues and bacterial contamination, and improving the sterilization effect and drug quality.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of sterilization equipment, in particular to a medicine sterilization system. High-temperature steam sterilization is replaced by circulating high-temperature airflow, no water stain is left, medicine powder is synchronously sterilized while the interior of tank equipment is sterilized, and the sterilization effect is further improved; comprising a tank body, a Venturi jet pump, a draught fan, a backflow air pipe, an air duct heater and a rotational flow assembly installed at the top of the tank body, a first material bin communicated with the interior of the tank body is arranged at the bottom of the tank body, a material spraying pipe with the discharging end facing upwards is fixedly installed in the middle of the interior of the tank body, and the material input end of the Venturi jet pump extends into the first material bin; the material output end of the Venturi jet pump is communicated with the material spraying pipe, an air outlet of the fan is communicated with the airflow input end of the Venturi jet pump, and the rotational flow assembly comprises an air outlet barrel fixedly installed at the top of the tank body, a rotational flow air barrel rotationally installed at the inner bottom of the air outlet barrel and a motor providing power for rotation of the rotational flow air barrel.
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Description

Technical Field

[0001] The utility model relates to the technical field of sterilization equipment, in particular to a drug sterilization system. Background Art

[0002] As we all know, in pharmaceutical production, cleaning and sterilization are two crucial links, which are directly related to the quality of drugs and the safety of patients' medication.

[0003] For example, Chinese utility model patent CN211099000U discloses a sterilization device for preparing freeze-dried powder injection of protein drugs, including a tank body and tank legs; a steam inlet and a steam outlet are respectively provided on opposite sides of the side wall of the tank body; the tank body is sterilized by passing high-temperature steam to ensure that the drug production process is in a sterile environment.

[0004] However, water stains will remain on the inner wall of the tank after high-temperature steam treatment. These residual water stains are prone to breed bacteria and will cause secondary pollution to subsequent drug powders. Moreover, it can only sterilize the inside of the tank equipment, and the drug powder will also be contaminated by bacteria during transportation. There is still a risk of these bacteria growing after entering the tank. Utility Model Content

[0005] In view of the deficiencies in the prior art, the utility model provides a drug sterilization system which uses circulating high-temperature airflow instead of high-temperature steam for sterilization, has no water stains remaining, sterilizes the inside of the tank equipment and simultaneously sterilizes the drug powder, thereby further improving the sterilization effect.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: the drug sterilization system comprises a tank body, a venturi jet pump, a fan, a return air duct, an air duct heater and a swirl assembly installed on the top of the tank body, the bottom of the tank body is provided with a first silo connected to the inside of the tank body, a spray pipe with a discharge end facing upward is fixedly installed in the middle of the tank body, the material input end of the venturi jet pump extends into the first silo, the material output end of the venturi jet pump is connected to the spray pipe, the air outlet of the fan is connected to the airflow input end of the venturi jet pump, the input end of the return air duct extends into the air outlet cylinder, the output end of the return air duct is connected to the suction end of the fan, and the air duct heater is installed in the return air duct.

[0007] Preferably, the swirl assembly includes an air outlet cylinder fixedly mounted on the top of the tank body, a swirl air cylinder rotatably mounted on the bottom of the air outlet cylinder, and a motor providing power for the rotation of the swirl air cylinder, and the swirl air cylinder is used to generate a rotating airflow inside the tank body.

[0008] Preferably, the cyclone fan comprises two frame plates and blades uniformly distributed circumferentially between the two frame plates, and the blades are arranged along the radial direction of the tank body.

[0009] Preferably, a feeding pipe communicating with the interior of the tank body is provided on the upper portion of the outer wall of the tank body.

[0010] Preferably, a sealing door is hingedly mounted on the feeding pipe.

[0011] Preferably, it also includes a sedimentation tank, a volute deflector installed on the top of the sedimentation tank, an air outlet pipe and a connecting pipe extending into the middle of the volute deflector, one end of the connecting pipe is connected to the inside of the air outlet cylinder, the other end of the connecting pipe is connected to the input end of the volute deflector, and the output end of the air outlet pipe is connected to the input end of the return air duct.

[0012] Preferably, a second silo communicating with the interior of the sedimentation tank is installed at the bottom of the sedimentation tank, and valves are installed at the upper feed point and the bottom discharge point of the first silo and the second silo.

[0013] Preferably, a plurality of groups of ultraviolet fluorescent tubes are installed in the air outlet pipe, the central axis of the ultraviolet fluorescent tubes is parallel to the central axis of the air outlet pipe, and the ultraviolet fluorescent tubes are evenly distributed in the circumferential direction of the air outlet pipe.

[0014] Preferably, a conical disperser is fixedly installed in the tank body, and the conical disperser is located between the spray pipe and the swirl air cylinder.

[0015] Preferably, a conical impeller is fixedly mounted on the bottom of the cyclone fan.

[0016] Compared with the prior art, the utility model provides a drug sterilization system with the following beneficial effects: the drug sterilization system starts the fan, and the fan sucks the airflow from the air outlet and the upper part of the tank body through the return air duct, and the air duct heater heats the airflow passing through the return air duct to at least 121°C, so that the high-temperature airflow achieves high-temperature sterilization of the inside of the tank body; the fan stops running, and the drug powder is put into the tank body through the feeding pipe, and the drug powder falls into the first silo, and the fan is started again, and the fan blows the heated high-temperature airflow into the Venturi jet pump, and the Venturi jet pump generates negative pressure due to the passage of high-speed airflow, and the drug powder in the first silo is sucked into the Venturi jet pump, and the drug powder The material and the high-temperature airflow are dispersedly contacted in the Venturi jet pump, the injection pipe and the inside of the tank body. The motor drives the swirl wind tube to rotate, and a swirl is generated in the upper part of the tank body. The drug powder is re-settled into the first silo under the action of the swirl, and the high-temperature gas re-enters the return air duct through the air outlet tube. In this way, the high-temperature airflow and the drug powder are circulated and contacted. The drug powder is sterilized by the high-temperature airflow. At the same time, the drug powder is evenly mixed again during the sterilization process of the drug powder, and the uniform configuration of the drug powder is achieved. The circulating high-temperature airflow replaces the high-temperature steam sterilization, and there is no water stain residue. The drug powder is sterilized synchronously while the inside of the tank equipment is sterilized, which further improves the sterilization effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a three-dimensional structural schematic diagram of the utility model.

[0018] Figure 2 It is a schematic diagram of the top plan structure of the utility model.

[0019] Figure 3 The utility model Figure 2 Schematic diagram of the cross-sectional structure at AA in the middle.

[0020] Figure 4 The utility model Figure 3 Schematic diagram of the cross-sectional structure at BB in the middle.

[0021] Figure 5 The utility model Figure 3 Schematic diagram of the partial enlarged structure at point C in the middle.

[0022] Markings in the attached drawings: 1. tank body; 2. Venturi jet pump; 3. fan; 4. return air duct; 5. duct heater; 6. first silo; 7. spray pipe; 8. air outlet tube; 9. motor; 10. feeding pipe; 11. sedimentation tank; 12. volute guide; 13. air outlet pipe; 14. connecting pipe; 15. ultraviolet fluorescent lamp tube; 16. conical disperser; 17. conical impeller; 18. frame plate; 19. blade plate; 20. sealing door; 21. second silo; 22. valve. DETAILED DESCRIPTION

[0023] In order to enable those skilled in the art to better understand the solution of the utility model, the technical solution in the embodiment of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiment of the utility model. Obviously, the described embodiment is only a part of the embodiment of the utility model, not all of the embodiments. Based on the embodiment of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work should fall within the scope of protection of the utility model.

[0024] It should be noted that, in the absence of conflict, the embodiments of the present invention and the features and technical solutions in the embodiments may be combined with each other.

[0025] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, further definition and explanation thereof is not required in subsequent drawings.

[0026] Example 1

[0027] Please refer to Figure 1-3A drug sterilization system comprises a tank body 1, a venturi jet pump 2, a fan 3, a return air duct 4, an air duct heater 5 and a swirl assembly installed on the top of the tank body 1. A first silo 6 communicating with the inside of the tank body 1 is provided at the bottom of the tank body 1. A spray pipe 7 with a discharge end facing upward is fixedly installed in the middle of the tank body 1. The material input end of the venturi jet pump 2 extends into the first silo 6, the material output end of the venturi jet pump 2 is communicated with the spray pipe 7, the air outlet of the fan 3 is communicated with the airflow input end of the venturi jet pump 2, and the swirl assembly comprises an air outlet cylinder 8 fixedly installed on the top of the tank body 1, a swirl air cylinder rotatably installed at the bottom of the air outlet cylinder 8, and an electric motor that provides power for the rotation of the swirl air cylinder. The machine 9 and the swirl fan are used to generate a rotating airflow inside the tank body 1. The input end of the return air duct 4 extends into the air outlet 8, and the output end of the return air duct 4 is connected with the suction end of the fan 3. The air duct heater 5 is installed in the return air duct 4. The air duct heater 5 is used to heat the airflow in the return air duct 4. A feeding pipe 10 connected with the inside of the tank body 1 is provided on the upper part of the outer wall of the tank body 1; further, the output end of the motor 9 is connected to the swirl fan through a rotating shaft; it should be noted that the drug sterilization system is suitable for high-temperature non-denatured drug powder sterilization and ingredient processing; when high-temperature denatured drug powder is configured, the air duct heater 5 is not started, and the drug sterilization system is only used for sterilization of the inside of the tank body 1.

[0028] Please refer to Figure 3 A conical impeller 17 is fixedly mounted at the bottom of the swirl duct; further, the tip of the conical impeller 17 faces downward.

[0029] For details, please refer to Figure 3-Figure 5 The swirl duct includes two frame plates 18 and blades 19 uniformly distributed circumferentially between the two frame plates 18, and the blades 19 are arranged along the radial direction of the tank body 1.

[0030] For details, please refer to Figure 3 ; A conical disperser 16 is fixedly installed in the tank body 1, and the conical disperser 16 is located between the spray pipe 7 and the cyclone air cylinder; further, the conical disperser 16 is welded by two hollow conical shells, and the two tips of the conical disperser 16 are respectively facing the spray pipe 7 and the cyclone air cylinder, and the maximum outer diameter of the conical disperser 16 is greater than or equal to the inner diameter of the spray pipe 7, and an annular channel of at least 10 cm is left between the maximum outer diameter of the conical disperser 16 and the inner wall of the tank body 1.

[0031] Please refer to Figure 2 , Figure 4 A sealing door 20 is hingedly mounted on the feeding pipe 10.

[0032] In the drug sterilization system provided in this embodiment, after the drug powder is loaded from the loading pipe 10, the sealing door 20 is in a closed state, so that the entire system is in a closed circulation state, reducing the airflow exchange with the external environment, thereby further preventing external bacteria from entering the system; a gap is left between two adjacent blades 19 to allow airflow to pass through, and when the swirl blower rotates at a high speed, the blades 19 disturb the upper airflow in the tank body 1, so that the upper airflow in the tank body 1 produces a swirl effect; and the conical impeller 17 can further disturb the upper airflow in the tank body 1 to further improve the airflow in the tank body 1. The swirl effect at the top can reduce the amount of drug powder entering the air outlet tube 8; the conical disperser 16 can evenly disperse the drug powder sprayed from the spray pipe 7 to the surroundings to improve the mixing uniformity between the drug powders, while reducing the drug powder from falling back into the spray pipe 7, and ensuring that the airflow sprayed from the spray pipe 7 is upward along the inner wall of the tank body 1, which plays a positive role in the subsequent swirl wind tube forming a swirl on the upper part of the tank body 1, and the conical disperser 16 can also reduce the airflow pressure, thereby avoiding excessive wind pressure in the tank body 1, so as to reduce the amount of drug powder following the airflow into the air outlet tube 8.

[0033] Example 2

[0034] The drug sterilization system provided in Example 1 is further optimized. For details, please refer to Figure 3 The drug sterilization system of this embodiment also includes a sedimentation tank 11, a volute deflector 12 installed on the top of the sedimentation tank 11, an air outlet pipe 13 and a connecting pipe 14 extending into the middle of the volute deflector 12, one end of the connecting pipe 14 is connected to the inside of the air outlet tube 8, and the other end of the connecting pipe 14 is connected to the input end of the volute deflector 12, and the output end of the air outlet pipe 13 is connected to the input end of the return air duct 4.

[0035] Specifically, a plurality of groups of ultraviolet fluorescent tubes 15 are installed in the air outlet pipe 13 , the central axis of the ultraviolet fluorescent tubes 15 is parallel to the central axis of the air outlet pipe 13 , and the ultraviolet fluorescent tubes 15 are evenly distributed in the circumferential direction of the air outlet pipe 13 .

[0036] A second silo 21 communicating with the interior of the silo 11 is installed at the bottom of the silo 11 , and valves 22 are installed at the upper feed point and the bottom discharge point of the first silo 6 and the second silo 21 .

[0037] The drug sterilization system provided in the present embodiment carries a small amount of drug powder in the air flow discharged through the connecting pipe 14. Under the action of the volute guide device 12, a vortex is formed in the sedimentation tank 11, and the drug powder is settled in the sedimentation tank 11 to avoid direct contact between the drug powder and the high-temperature air duct heater 5; the ultraviolet fluorescent lamp in the outlet pipe 13 can perform ultraviolet sterilization on the circulating air flow flowing through, further reducing the survival rate of bacteria and improving the sterilization effect; the first silo 6 and the second silo 21 are used for storing pharmaceutical powder. When unloading is required, the valve 22 at the upper part of the first silo 6 and the second silo 21 is closed, and the lower valve 22 is opened to discharge the powder in the first silo 6 and the second silo 21. The valve 22 is used to isolate the interior of the system from the external environment, further reducing the entry of external bacteria into the system and further reducing the risk of bacterial growth in the system.

[0038] The use process of the drug sterilization system provided by the utility model is as follows: by starting the fan 3, the fan 3 sucks the air outlet 8 and the upper airflow in the tank body 1 through the return air duct 4, and the air duct heater 5 heats the airflow flowing through the return air duct 4 to at least 121°C, and the high-temperature airflow achieves high-temperature sterilization of the inside of the tank body 1; the fan 3 stops running, and the drug powder is put into the tank body 1 through the feeding pipe 10, and the sealing door 20 is closed, and the drug powder falls into the first silo 6 under the action of gravity; then the fan 3 is started again, and the fan 3 blows the heated high-temperature airflow into the Venturi jet pump 2, and the Venturi jet pump 2 generates negative pressure due to the passage of high-speed airflow, and the first silo The drug powder in the bin 6 is sucked into the Venturi jet pump 2, and the drug powder is dispersedly contacted with the high-temperature airflow in the Venturi jet pump 2, the injection pipe 7 and the inside of the tank body 1. The motor 9 drives the swirl wind tube to rotate, and a swirl is generated in the upper part of the tank body 1. The drug powder is re-settled into the first bin 6 under the action of the swirl, and the high-temperature gas enters the sedimentation tank 11 through the air outlet tube 8, the connecting pipe 14 and the volute guide 12. Part of the drug powder carried by the airflow is settled in the sedimentation tank 11, and the airflow re-enters the return air duct 4 through the air outlet pipe 13. In this way, the high-temperature airflow and the drug powder are circulated and contacted, and the drug powder is sterilized at high temperature by the high-temperature airflow.

[0039] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral one; it can be a mechanical connection, an electrical connection, or communication with each other; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

Claims

1. A drug sterilization system, characterized in that: The invention comprises a tank body (1), a venturi jet pump (2), a fan (3), a return air duct (4), an air duct heater (5), and a swirl assembly installed on the top of the tank body (1). The bottom of the tank body (1) is provided with a first material bin (6) which is connected to the inside of the tank body (1). A spray pipe (7) with a discharge end facing upward is fixedly installed in the middle of the tank body (1). The material input end of the venturi jet pump (2) extends into the first material bin (6). The material output end of the venturi jet pump (2) is connected to the spray pipe (7). The air outlet of the fan (3) is connected to the air flow input end of the venturi jet pump (2). The input end of the return air duct (4) extends into the air outlet cylinder (8). The output end of the return air duct (4) is connected to the air intake end of the fan (3). The air duct heater (5) is installed in the return air duct (4).

2. The drug sterilization system according to claim 1, characterized in that: The swirl assembly comprises an air outlet cylinder (8) fixedly mounted on the top of the tank body (1), a swirl air cylinder rotatably mounted on the bottom of the air outlet cylinder (8), and a motor (9) providing power for the rotation of the swirl air cylinder. The swirl air cylinder is used to generate a swirling airflow inside the tank body (1).

3. The drug sterilization system according to claim 2, characterized in that: The cyclone fan comprises two frame plates (18) and blade plates (19) uniformly distributed circumferentially between the two frame plates (18), wherein the blade plates (19) are arranged along the radial direction of the tank body (1).

4. The drug sterilization system according to claim 1, characterized in that: A feeding pipe (10) communicating with the interior of the tank body (1) is provided on the upper portion of the outer wall of the tank body (1).

5. The drug sterilization system according to claim 4, characterized in that: A sealing door (20) is hingedly mounted on the feeding pipe (10).

6. The drug sterilization system according to claim 1, characterized in that: It also includes a sedimentation tank (11), a volute flow guide (12) installed on the top of the sedimentation tank (11), an air outlet pipe (13) and a connecting pipe (14) extending into the middle of the volute flow guide (12), one end of the connecting pipe (14) is connected to the inside of the air outlet cylinder (8), the other end of the connecting pipe (14) is connected to the input end of the volute flow guide (12), and the output end of the air outlet pipe (13) is connected to the input end of the return air pipe (4).

7. The drug sterilization system according to claim 6, characterized in that: A second silo (21) communicating with the interior of the silo (11) is installed at the bottom of the silo (11), and valves (22) are installed at the upper feed point and the bottom discharge point of the first silo (6) and the second silo (21).

8. The drug sterilization system according to claim 6, characterized in that: A plurality of groups of ultraviolet fluorescent tubes (15) are installed in the air outlet pipe (13); the central axis of the ultraviolet fluorescent tubes (15) is parallel to the central axis of the air outlet pipe (13); and the ultraviolet fluorescent tubes (15) are evenly distributed in the circumferential direction of the air outlet pipe (13).

9. The drug sterilization system according to claim 2, characterized in that: A conical disperser (16) is fixedly installed in the tank body (1), and the conical disperser (16) is located between the spray pipe (7) and the cyclone cylinder.

10. The drug sterilization system according to claim 9, characterized in that: A conical impeller (17) is fixedly mounted on the bottom of the cyclone fan.

Citation Information

Patent Citations

  • Degerming device for preparing protein drug freeze-dried powder injection

    CN211099000U