Filtering and regrinding device for biopharmacy

By designing a filter tank and a vibration motor in the biopharmaceutical grinding equipment to filter the drug raw materials, and then re-grinding with the belt transmission system, the problem of small particles in the drug raw materials affecting the quality of the drug is solved, and a more efficient drug polishing and filtration effect is achieved.

CN222766472UActive Publication Date: 2025-04-18KUNMING XUFENG BIOPHARMACEUTICAL CO LTD
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Patent Information

Application Number
CN202421273176.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-05
Publication Date
2025-04-18
Estimated Expiration
2034-06-05

AI Technical Summary

Technical Problem

After grinding the existing biopharmaceutical grinding equipment, there are still small particles that are difficult to deal with in the drug raw materials, which affects the quality of the drug and the effectiveness of use.

Method used

A filtration and re-grinding device for biopharmaceuticals is designed, including a filter tank and a vibrating motor to filter the drug raw materials, and the filtered drug raw materials are driven by the belt transmission system to drive the grinding shaft and grinding wheel to re-grind the filtered drug raw materials.

Benefits of technology

Through the combination of the filter tank and the vibration motor, the fine particles in the drug raw materials can be effectively removed and the drug quality is improved. At the same time, the use of the belt transmission system allows the drug raw materials to be evenly ground and improve the grinding efficiency.

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Abstract

The filtering and regrinding device comprises a main body installation frame, a feeding hopper is fixedly installed on the front side of the upper end of the main body installation frame in a supporting mode, an upper feeding groove is fixedly formed in the outer side of the lower end of the feeding hopper, and an upper electric telescopic rod is fixedly installed on the rear side of the upper end of the main body installation frame. An upper push plate is fixedly mounted on the telescopic part of the front end of the upper electric telescopic rod, a filter tank used for filtering medicine raw materials is fixedly mounted on the front side of the upper end of the middle of the main body mounting frame, and vibration motors are fixedly mounted in the middles of the two sides of the filter tank; a collecting tank is fixedly mounted on the front side of the lower end of the main body mounting frame, an auxiliary mounting frame is fixedly mounted on the front side of the lower end of the main body mounting frame, and an upper collecting box is fixedly mounted at the upper end of the auxiliary mounting frame. According to the medicine raw material filtering device, medicine raw materials can be conveniently filtered, and meanwhile the filtered medicine raw materials can be conveniently ground again.
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Description

Technical Field

[0001] The utility model relates to the technical field of biopharmaceuticals, in particular to a filtering and re-grinding device for biopharmaceuticals. Background Art

[0002] Biopharmaceuticals refer to a type of products used for prevention, treatment and diagnosis that are manufactured from organisms, biological tissues, cells, organs, body fluids, etc., using the research results of microbiology, biology, medicine, biochemistry, etc., and comprehensively utilizing the scientific principles and methods of microbiology, chemistry, biochemistry, biotechnology, pharmacy, etc. Biopharmaceutical raw materials are mainly natural biological materials, including microorganisms, human bodies, animals, plants, marine organisms, etc. With the development of biotechnology, purposefully artificially produced biological raw materials have become the main source of current biopharmaceutical raw materials.

[0003] When making biopharmaceuticals, grinding equipment is usually used to grind and crush the drug raw materials for subsequent production and use of the drug raw materials;

[0004] However, in actual use of the prior art, after the drug raw materials are ground and pulverized by a grinding device, some small particles that are difficult to handle still exist in the pulverized drug raw material powder, and these small particles will affect the subsequent quality and use effect of the drug. Utility Model Content

[0005] The purpose of the utility model is to provide a filtering and re-grinding device for biopharmaceuticals to solve the problem raised in the above-mentioned background technology that after the drug raw materials are usually ground and pulverized by grinding equipment, some difficult-to-handle fine particles still exist in the pulverized drug raw material powder, and these fine particles will affect the subsequent quality and use effect of the drug.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: comprising a main body mounting frame, a feeding hopper is fixedly installed on the front side support of the upper end of the main body mounting frame, an upper feeding trough is fixedly installed on the outer side of the lower end of the feeding hopper, an upper electric telescopic rod is fixedly installed on the rear side of the upper end of the main body mounting frame, an upper push plate is fixedly installed on the telescopic part of the front end of the upper electric telescopic rod, a filter tank for filtering drug raw materials is fixedly installed on the front side of the upper middle end of the main body mounting frame, a vibration motor is fixedly installed on the middle of both sides of the filter tank, a collecting tank is fixedly installed on the front side of the lower end of the main body mounting frame, a sub-mounting frame is fixedly installed on the front side of the lower end of the main body mounting frame, and an upper collecting box is fixedly installed on the upper end of the sub-mounting frame;

[0007] A guide groove is fixedly installed on the rear side of the upper middle part of the main body mounting frame, a lower feed trough is fixedly installed on the front side of the lower end of the main body mounting frame, a lower electric telescopic rod is fixedly installed on the rear side of the lower end of the main body mounting frame, and a lower push plate is fixedly installed on the telescopic part at the front end of the lower electric telescopic rod;

[0008] A driving motor is fixedly installed on the outer side of the front end of the auxiliary mounting frame, a main pulley is fixedly installed on the transmission shaft part inside the driving motor, the outer end of the main pulley is connected to the auxiliary pulley through belt transmission, a grinding shaft is fixedly installed in the middle of the auxiliary pulley, a grinding chamber is supported and fixedly installed on the upper end of the inner side of the auxiliary mounting frame, a main grinding wheel is fixedly installed on the outer curved surface in the middle of the grinding shaft, the inner wall of the lower end of the grinding chamber is rotatably connected to the auxiliary grinding wheel through a rotating shaft, a discharge port is opened through the bottom of the grinding chamber, and a lower collecting box is movably connected to the bottom of the auxiliary mounting frame.

[0009] Preferably, the outer side of the upper push plate is movably connected to the inner wall of the upper feed trough.

[0010] Preferably, the rear end of the filter tank is tilted downward, a filter hole for filtering drug raw materials is provided at the bottom of the filter tank, and the front side of the upper end of the filter tank and the front side of the lower end of the upper feed tank are interconnected.

[0011] Preferably, there are two vibration motors, which are symmetrically distributed in the middle of both sides of the filter tank, and the rear end of the collection tank extends upward to the bottom of the rear end of the filter tank.

[0012] Preferably, the front end of the guide groove is inclined downward, the upper end of the guide groove is located at the bottom of the lower end of the filter groove, the lower end of the guide groove extends to the rear side of the upper end of the lower feed groove, and the outer side of the lower push plate is movably connected to the inner wall of the lower feed groove.

[0013] Preferably, the front side of the upper end of the grinding chamber and the front end of the lower feed trough are connected to each other, and the grinding shaft is rotatably connected to the middle of the grinding chamber through a rotating shaft.

[0014] Preferably, there are three auxiliary grinding wheels, which are symmetrically distributed on the inner wall of the lower end of the grinding chamber.

[0015] Compared with the prior art, the beneficial effects of the utility model are:

[0016] 1. The utility model filters the drug raw materials through the filter holes at the bottom of the filter tank. When the drug raw materials are filtered, the vibration motor is turned on by control. When the vibration motor is turned on, the middle of the filter tank is driven to vibrate. The vibration of the middle of the filter tank can accelerate the filtering of the drug raw materials and avoid the accumulation of drug raw materials. At the same time, the filtered drug raw material powder will slide along the collection tank to the inside of the upper collection box, thereby facilitating the filtering of the drug raw materials.

[0017] 2. The utility model also controls to start the driving motor when the drug raw material particles are pushed into the grinding chamber. When the driving motor is turned on, it will drive the main pulley to rotate. When the main pulley rotates, it will drive the secondary pulley to rotate through the belt transmission. When the secondary pulley rotates, it will drive the grinding shaft to rotate. When the grinding shaft rotates, it will drive the main grinding wheel to rotate. When the main grinding wheel rotates, it will cooperate with the secondary grinding wheel to roll and grind the drug raw materials entering the grinding chamber, and discharge the ground drug raw material powder into the lower collection box through the discharge port, thereby facilitating the filtering of the drug raw materials and re-grinding the filtered drug raw materials. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 The overall structure of the utility model of a biopharmaceutical filtering and grinding device is shown in FIG. Figure 1 ;

[0019] Figure 2 The overall structure of the utility model of a biopharmaceutical filtering and grinding device is shown in FIG. Figure 2 ;

[0020] Figure 3 The overall structure of the utility model of a biopharmaceutical filtering and grinding device is shown in FIG. Figure 3 ;

[0021] Figure 4 The utility model is a schematic cross-sectional view of the overall structure of a filtering and regrinding device for biopharmaceuticals.

[0022] In the figure: 1. main mounting frame; 2. feeding hopper; 3. upper feed trough; 4. upper electric telescopic rod; 5. upper push plate; 6. filter trough; 7. vibration motor; 8. auxiliary mounting frame; 9. upper collecting box; 10. lower feed trough; 11. lower electric telescopic rod; 12. lower push plate; 13. driving motor; 14. main pulley; 15. auxiliary pulley; 16. grinding shaft; 17. grinding chamber; 18. main grinding wheel; 19. auxiliary grinding wheel; 20. discharge port; 21. lower collecting box; 22. collecting trough; 23. guide trough. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0024] See also Figure 1-4 The utility model provides a technical solution of a filtering and re-grinding device for biopharmaceuticals: it comprises a main body mounting frame 1, a feeding hopper 2 is fixedly mounted on the front side of the upper end of the main body mounting frame 1, an upper feeding trough 3 is fixedly mounted on the outer side of the lower end of the feeding hopper 2, an upper electric telescopic rod 4 is fixedly mounted on the rear side of the upper end of the main body mounting frame 1, an upper push plate 5 is fixedly mounted on the front end telescopic part of the upper electric telescopic rod 4, and the outer side of the upper push plate 5 is movably connected to the inner wall of the upper feeding trough 3, a filtering tank 6 for filtering drug raw materials is fixedly mounted on the front side of the upper end of the middle part of the main body mounting frame 1, and the filter tank 6 is fixedly mounted on the rear side of the filter tank 6. The end is tilted downward, and a filter hole for filtering the drug raw materials is opened in the bottom of the filter tank 6. The front side of the upper end of the filter tank 6 and the front side of the lower end of the upper feed tank 3 are mutually connected. A vibration motor 7 is fixedly installed in the middle of both sides of the filter tank 6, and there are two vibration motors 7, which are symmetrically distributed in the middle of both sides of the filter tank 6. A collection tank 22 is fixedly installed at the front side of the lower end of the main mounting frame 1, and the rear end of the collection tank 22 extends upward to the bottom of the rear end of the filter tank 6. A sub-mounting frame 8 is fixedly installed at the front side of the lower end of the main mounting frame 1, and an upper collecting box 9 is fixedly installed at the upper end of the sub-mounting frame 8;

[0025] A guide groove 23 is fixedly installed on the rear side of the upper middle part of the main mounting frame 1, and the front end of the guide groove 23 is inclined downward, the upper end of the guide groove 23 is located at the bottom of the lower end of the filter tank 6, and a lower feed trough 10 is fixedly installed on the front side of the lower end of the main mounting frame 1. The lower end of the guide groove 23 extends to the rear side of the upper end of the lower feed trough 10. A lower electric telescopic rod 11 is fixedly installed on the rear side of the lower end of the main mounting frame 1. A lower push plate 12 is fixedly installed on the telescopic part of the front end of the lower electric telescopic rod 11, and the outer side of the lower push plate 12 is movably connected to the inner wall of the lower feed trough 10;

[0026] A driving motor 13 is fixedly installed on the outer side of the front end of the auxiliary mounting frame 8, and a main pulley 14 is fixedly installed on the transmission shaft part inside the driving motor 13. The outer end of the main pulley 14 is connected to a secondary pulley 15 through belt transmission, and a grinding shaft 16 is fixedly installed in the middle of the secondary pulley 15. A grinding chamber 17 is supported and fixedly installed on the upper end of the inner side of the auxiliary mounting frame 8, and the front side of the upper end of the grinding chamber 17 is connected to the front end of the lower feed trough 10 through each other, and the grinding shaft 16 is rotatably connected to the middle of the grinding chamber 17 through a rotating shaft, and a main grinding wheel 18 is fixedly installed on the outer curved surface of the middle part of the grinding shaft 16, and the inner wall of the lower end of the grinding chamber 17 is rotatably connected to a secondary grinding wheel 19 through a rotating shaft, and there are three secondary grinding wheels 19, which are symmetrically distributed on the inner wall of the lower end of the grinding chamber 17, and a discharge port 20 is opened at the bottom of the grinding chamber 17, and a lower collecting box 21 is movably connected to the bottom of the auxiliary mounting frame 8.

[0027] Working principle: When in use, the utility model puts the drug raw materials that need to be filtered and then ground into the bottom of the feeding hopper 2. When the drug raw materials that need to be filtered and then ground are put into the bottom of the feeding hopper 2, the upper electric telescopic rod 4 is controlled to be turned on. When the upper electric telescopic rod 4 is turned on, it will drive the upper push plate 5 to move forward. When the upper push plate 5 moves forward, it will push the drug raw materials at the bottom of the feeding hopper 2 forward to the filter tank 6. When the drug raw materials are pushed forward to the upper end of the filter tank 6, the drug raw materials will fall downward due to the force of their own gravity. At the same time, the drug raw materials are filtered through the filter holes opened in the bottom of the filter tank 6. When the drug raw materials are filtered, the vibration motor 7 is controlled to be turned on. When the vibration motor 7 is turned on, it will drive the middle part of the filter tank 6 to vibrate. The vibration of the middle part of the filter tank 6 can accelerate the filtration of the drug raw materials and avoid the accumulation of drug raw materials. At the same time, the filtered drug raw material powder will slide along the collecting tank 22 to the inside of the upper collecting box 9, thereby facilitating the filtering of the drug raw materials.

[0028] At the same time, the drug raw material particles that have not been filtered through the filter holes will roll down along the filter groove 6 and fall into the guide groove 23, and roll down through the guide groove 23 and fall into the lower feed groove 10. When the drug raw material particles fall into the lower feed groove 10, the lower electric telescopic rod 11 is turned on by control. When the lower electric telescopic rod 11 is turned on, the lower push plate 12 is pushed forward. When the lower push plate 12 moves forward, the drug raw material particles in the lower feed groove 10 are pushed into the grinding chamber 17. When the drug raw material particles are pushed into the grinding chamber 17, the drive motor 13 is turned on by control. When the drive motor 13 is turned on, it drives the main The pulley 14 rotates. When the main pulley 14 rotates, it will drive the secondary pulley 15 to rotate through the belt transmission. When the secondary pulley 15 rotates, it will drive the grinding shaft 16 to rotate. When the grinding shaft 16 rotates, it will drive the main grinding wheel 18 to rotate. When the main grinding wheel 18 rotates, it will cooperate with the secondary grinding wheel 19 to roll and grind the drug raw materials entering the grinding chamber 17, and discharge the ground drug raw material powder into the lower collecting box 21 through the discharge port 20, so as to facilitate the filtering of the drug raw materials and the re-grinding of the filtered drug raw materials.

[0029] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0030] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A biopharmaceutical filtering and regrinding device, characterized in that: The invention comprises a main body mounting frame (1), wherein a feeding hopper (2) is fixedly mounted on the front support of the upper end of the main body mounting frame (1), an upper feeding trough (3) is fixedly mounted on the outer side of the lower end of the feeding hopper (2), an upper electric telescopic rod (4) is fixedly mounted on the rear side of the upper end of the main body mounting frame (1), an upper push plate (5) is fixedly mounted on the front telescopic part of the front end of the upper electric telescopic rod (4), a filter trough (6) for filtering drug raw materials is fixedly mounted on the front side of the middle upper end of the main body mounting frame (1), a vibration motor (7) is fixedly mounted on the middle of both sides of the filter trough (6), a collecting trough (22) is fixedly mounted on the front side of the lower end of the main body mounting frame (1), a sub-mounting frame (8) is fixedly mounted on the front side of the lower end of the main body mounting frame (1), and an upper collecting box (9) is fixedly mounted on the upper end of the sub-mounting frame (8); A guide groove (23) is fixedly installed on the rear side of the middle upper end of the main body mounting frame (1), a lower feed trough (10) is fixedly installed on the front side of the lower end of the main body mounting frame (1), a lower electric telescopic rod (11) is fixedly installed on the rear side of the lower end of the main body mounting frame (1), and a lower push plate (12) is fixedly installed on the front end telescopic part of the lower electric telescopic rod (11); A driving motor (13) is fixedly mounted on the outer side of the front end of the auxiliary mounting frame (8); a main pulley (14) is fixedly mounted on the transmission shaft portion inside the driving motor (13); the outer end of the main pulley (14) is connected to a secondary pulley (15) through a belt transmission; a grinding shaft (16) is fixedly mounted in the middle of the secondary pulley (15); a grinding chamber (17) is fixedly mounted on the upper end support of the inner side of the auxiliary mounting frame (8); a main grinding wheel (18) is fixedly mounted on the outer curved surface of the middle part of the grinding shaft (16); an auxiliary grinding wheel (19) is rotatably connected to the inner wall of the lower end of the grinding chamber (17) through a rotating shaft; a discharge port (20) is opened through the bottom of the grinding chamber (17); and a lower collecting box (21) is movably connected to the bottom of the auxiliary mounting frame (8).

2. A biopharmaceutical filtering and regrinding device according to claim 1, characterized in that: The outer side of the upper push plate (5) is movably connected to the inner wall of the upper feed trough (3).

3. A biopharmaceutical filtering and regrinding device according to claim 2, characterized in that: The rear end of the filter tank (6) is inclined downward, and a filter hole for filtering the drug raw materials is provided at the bottom of the filter tank (6). The front side of the upper end of the filter tank (6) and the front side of the lower end of the upper feed tank (3) are interconnected.

4. A biopharmaceutical filtering and regrinding device according to claim 3, characterized in that: There are two vibration motors (7), which are symmetrically distributed in the middle of both sides of the filter tank (6), and the rear end of the collection tank (22) extends upward to the bottom of the rear end of the filter tank (6).

5. A biopharmaceutical filtering and regrinding device according to claim 4, characterized in that: The front end of the guide groove (23) is inclined downward, the upper end of the guide groove (23) is located at the bottom of the lower end of the filter groove (6), the lower end of the guide groove (23) extends to the rear side of the upper end of the lower feed groove (10), and the outer side of the lower push plate (12) is movably connected to the inner wall of the lower feed groove (10).

6. A biopharmaceutical filtering and regrinding device according to claim 5, characterized in that: The front side of the upper end of the grinding chamber (17) and the front end of the lower feed trough (10) are connected to each other, and the grinding shaft (16) is rotatably connected to the middle of the grinding chamber (17) via a rotating shaft.

7. A biopharmaceutical filtering and regrinding device according to claim 6, characterized in that: There are three auxiliary grinding wheels (19), which are symmetrically distributed on the inner wall of the lower end of the grinding chamber (17).